MedWorm: Laser Surgery

In vivo comparison of near infrared lasers for skin welding

Lasers in Medical Science — Tue, 17 Nov 2009 23:47:10 +0100

Abstract The skin closure abilities of near infrared lasers and suturing were compared by histological examination and mechanical tensile tests during a 21-day healing period. One-centimeter incisions on the dorsal skin of Wistar rats were treated by one of the closing techniques: (a) soldering, using an 809 nm diode laser (0.5 W, 5 s) with 25% bovine serum albumin (BSA) and 2.5 mg/ml indocyanine green (ICG); (b) direct welding with a 980 nm diode laser (0.5 W, 5 s); (c) direct welding with a 1,070 nm fiber laser (0.5 W, 5 s); (d) suturing. Six spots (79.61 J/cm2 for each spot) were applied through the incisions. Healing was inspected on the 1st, 4th, 7th, 14th, and 21st post-operative days. The closure index (CI), ther...

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Laser Photobiomodulation of Wound Healing in Diabetic and Non-Diabetic Mice: Effects in Splinted and Unsplinted Wounds

Photomedicine and Laser Surgery — Mon, 16 Nov 2009 18:03:59 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

As Seen in Forbes Magazine Top 10 LASIK centers in the United States

Dishler Laser — Sun, 15 Nov 2009 15:49:50 +0100

In 1995 we were one of the first ten LASIK providers in the United States. This was a new procedure at that time almost 15 years ago, and since that time the success of that procedure has blossomed into an industry with over 10,000 LASIK providers today. It is certainly impossible to say who or where is the very best LASIK providers, but it is always good to be considered amongst the best. When one reviews the doctors and centers picked for the prestigious Goldline independent consumer research of best or most dependable LASER VISION providers in the last few years, it is obvious that they have picked very well recognized and credible choices. This year we were notified a few weeks ago, that we were selected by Goldline as one of only 10 LASIK practices in the entir...

One Picture is Worth a Thousand Words

Dishler Laser — Sat, 07 Nov 2009 15:48:35 +0100

www.dishler.com/pages/technology#zywave (Source: Dishler Laser)

Changes in Cell Viability of Wounded Fibroblasts following Laser Irradiation in Broad-Spectrum or Infrared Light

Laser Chemistry — Tue, 03 Nov 2009 16:02:49 +0100

Conclusion. Wounded cells irradiated in IR light showed an undesirable thermal effect that was proportional to the duration of exposure. (Source: Laser Chemistry)

Managing Postmastectomy Lymphedema with Low-Level Laser Therapy

Photomedicine and Laser Surgery — Sun, 01 Nov 2009 12:16:59 +0100

Photomedicine and Laser Surgery Oct 2009, Vol. 27, No. 5: 763-769. (Source: Photomedicine and Laser Surgery)

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Assessment of Neodymium:Yttrium-Aluminum-Garnet (Nd:YAG) Laser Fiber Wear and Tear Grade During Visual Laser Ablation of Prostatic Adenoma

Photomedicine and Laser Surgery — Sun, 01 Nov 2009 12:16:42 +0100

Photomedicine and Laser Surgery Oct 2009, Vol. 27, No. 5: 799-805. (Source: Photomedicine and Laser Surgery)

Dental Enamel Irradiated with Infrared Diode Laser and Photo-Absorbing Cream: Part 2—EDX Study

Photomedicine and Laser Surgery — Sun, 01 Nov 2009 12:16:21 +0100

Photomedicine and Laser Surgery Oct 2009, Vol. 27, No. 5: 771-782. (Source: Photomedicine and Laser Surgery)

Laser Light May Improve the Symptoms of Oral Lesions of Cicatricial Pemphigoid: A Case Report

Photomedicine and Laser Surgery — Sun, 01 Nov 2009 12:15:07 +0100

Photomedicine and Laser Surgery Oct 2009, Vol. 27, No. 5: 825-828. (Source: Photomedicine and Laser Surgery)

Calendar of Laser Courses and Meetings

Photomedicine and Laser Surgery — Sun, 01 Nov 2009 12:12:15 +0100

Photomedicine and Laser Surgery Oct 2009, Vol. 27, No. 5: 831-832. (Source: Photomedicine and Laser Surgery)

Photomedicine and LLLT Literature Watch

Photomedicine and Laser Surgery — Sun, 01 Nov 2009 12:12:14 +0100

Photomedicine and Laser Surgery Oct 2009, Vol. 27, No. 5: 829-829. (Source: Photomedicine and Laser Surgery)

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Synergistic Increase in Osteosarcoma Cell Sensitivity to Photodynamic Therapy with Aminolevulinic Acid Hexyl Ester in the Presence of Hyperthermia

Photomedicine and Laser Surgery — Sun, 01 Nov 2009 12:11:46 +0100

Photomedicine and Laser Surgery Oct 2009, Vol. 27, No. 5: 791-797. (Source: Photomedicine and Laser Surgery)

Molecular Perspectives of Wound Healing—Cellular Models*

Photomedicine and Laser Surgery — Sun, 01 Nov 2009 12:11:27 +0100

Photomedicine and Laser Surgery Oct 2009, Vol. 27, No. 5: 693-694. (Source: Photomedicine and Laser Surgery)

Effect of Low-Level Laser Therapy on Malondialdehyde Concentration in Random Cutaneous Flap Viability

Photomedicine and Laser Surgery — Fri, 30 Oct 2009 16:12:53 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Investigation of the Effect of GaAs Laser Therapy on Lateral Epicondylitis

Photomedicine and Laser Surgery — Fri, 30 Oct 2009 16:02:49 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

How to know if you will be happy with LASIK vision correction

Dishler Laser — Fri, 30 Oct 2009 16:00:30 +0100

If you are the kind of person who is extremely difficult to satisfy, who demands absolute perfection, and who gets easily flustered with even the slightest delay, then LASIK may not be your best option. If on the other hand, you are looking for a substantial improvement in your vision to improve your quality of life which you overall find satisfactory except for the problems associated with glasses or contact lenses, then you are probably a good LASIK candidate. If you meet this test, then the next step is to find your best option for obtaining your vision improvement. To be happy with LASIK you must believe that you made a reasoned choice in LASIK providers. Most importantly, try to find a good referral source to a doctor beyond advertising o...

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Therapeutic Effects of Low-Level Laser on Lateral Epicondylitis from Differential Interventions of Chinese-Western Medicine: Systematic Review

Photomedicine and Laser Surgery — Fri, 30 Oct 2009 10:55:45 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Low-Level Laser Therapy for Implants Without Initial Stability

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 22:10:35 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Evaluation of Oxygen Consumption of Culture Medium and In Vitro Photodynamic Effect of Talaporfin Sodium in Lung Tumor Cells

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 22:05:10 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effect of Biostimulation on Healing of Bone Defects in Diabetic Rats

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 21:58:01 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Validating a Nonacupoint Sham Control for Laser Treatment of Knee Osteoarthritis

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 21:58:00 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Effect of Two Kinds of Er:YAG Laser Systems on Root Surface in Comparison to Ultrasonic Scaling: An in Vitro Study

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 21:49:52 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Root Surface Biomodification With Nd:YAG Laser For The Treatment Of Gingival Recession With Subepithelial Connective Tissue Grafts

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 21:46:52 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

The Association of Low and High Laser Treatments on Self-Inflicted Lip Injury: A Case Report

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 21:42:27 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effects of Combined Use of Light Irradiation and 35% Hydrogen Peroxide for Dental Bleaching on Human Enamel Mineral Content

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 18:25:54 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

FT-Raman and Energy Dispersive X-Ray Fluorescence Spectrometric Analyses of Enamel Submitted to 38% Hydrogen Peroxide Bleaching, an Acidic Beverage, and Simulated Brushing

Photomedicine and Laser Surgery — Tue, 27 Oct 2009 18:21:58 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Are there advantages to i-LASIK?

Dishler Laser — Mon, 26 Oct 2009 16:33:37 +0100

It is important to distinguish real technological advancements, from marketing hype and this is especially true when it comes to laser vision correction. There is not much question that I-LASIK is the latter of these in that it was the matching of two existing technologies. The VISX laser was one of the first approved lasers, and although there have been some improvements, it is still a broad beam first generation technology which is limited as compared to many newer lasers that have been available for a number of years since. Yes, there is a good chance of getting to 20/20 vision with VISX but no greater than any other platform, and it has limitations in the type of ablation that can be created. This gets into subtler issues than just 20/20. For instance, it ...

Effect of GaAlAs Laser Irradiation on Enzyme Activity

Photomedicine and Laser Surgery — Mon, 26 Oct 2009 14:54:22 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Healing of Surgical Wounds Made with λ970-nm Diode Laser Associated or Not with Laser Phototherapy (λ655 nm) or Polarized Light (λ400–2000 nm)

Photomedicine and Laser Surgery — Mon, 26 Oct 2009 14:50:40 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Treatment of Faun-Tail Naevus with Intense Pulsed Light

Photomedicine and Laser Surgery — Mon, 26 Oct 2009 14:50:39 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Shear Bond Strength of Repair Composite Resin to an Acid-Etched and a Laser-Irradiated Feldspathic Ceramic Surface

Photomedicine and Laser Surgery — Fri, 23 Oct 2009 15:25:01 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Fractional Photothermolysis: Non-Ablative and Ablative

Aesthetic Lasers — Fri, 23 Oct 2009 14:14:27 +0100

The concept of non-ablative fractional photothermolysis was introduced to the market in 2003 as an answer to the need for effective, yet low risk, skin resurfacing techniques. Unlike conventional ablative (CO2 and Erbium) and non-ablative lasers, fractional ablative and non-ablative photothermolysis treats only a fraction of the skin, leaving up to a maximum of 95% [...]Post from: Aesthetic Laser OffersFractional Photothermolysis: Non-Ablative and Ablative (Source: Aesthetic Lasers)

Laser Florence 2009

Lasers in Medical Science — Thu, 22 Oct 2009 05:58:22 +0100

Content Type Journal ArticleDOI 10.1007/s10103-009-0735-7 Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 Journal Volume Volume 24 Journal Issue Volume 24, Supplement 1 / October, 2009 (Source: Lasers in Medical Science)

Who is the 'LASIK patient counselor' and why should you care?

Dishler Laser — Wed, 21 Oct 2009 15:16:31 +0100

Concierge is a French term and originally applied only to hotels as a person who helped guests with services related to their stay. In America and elsewhere the term has been extended to a broader range of meanings. The Wikipedia defines a "Hospital Concierge" as: 'In hospitals, concierge services are becoming increasingly available. A hospital concierge provides similar services to those of a hotel concierge, but serve patients and employees as well'. It is not so important what the term is but rather the qualifications and duties of the person involved. At Dishler Laser Institute, our patient counselor, Dana C., is a registered nurse (RN). She has worked at our facility for a number of years in a variety of nursing duties including scr...

Nd:YAG Laser Treatment of Warts

Aesthetic Lasers — Wed, 21 Oct 2009 14:13:46 +0100

Warts are ugly but they are common, and there are many ways and means to remove them. I prefer to use a YAG laser to remove warts. Surprisingly, this simple technique is not very common among dermatologists who typically freeze warts with nitrogen. That is painful and not very effective as in many cases more than [...]Post from: Aesthetic Laser OffersNd:YAG Laser Treatment of Warts (Source: Aesthetic Lasers)

Ultrasonographic evaluation of plantar fasciitis after low-level laser therapy: results of a double-blind, randomized, placebo-controlled trial

Lasers in Medical Science — Wed, 21 Oct 2009 02:55:38 +0100

Abstract The aim of this study was to investigate the effect of low-level laser therapy (LLLT) on plantar fasciitis documented by the ultrasonographic appearance of the aponeurosis and by patients’ pain scores. Thirty individuals with diagnosis of unilateral plantar fasciitis were enrolled in a randomized, double-blind, placebo-controlled trial, but 25 participants completed the therapeutic protocol. The contralateral asymptomatic fascia was used as control. After enrolment, symptomatic individuals were randomly assigned to receive LLLT, or identical placebo, for 6 weeks. Ultrasonography was performed at baseline and after completion of therapy. The subjective subcalcaneal pain was recorded at baseline and after treatment on a visual analogue scale (VAS). After LLLT...

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Nothing to fear but fear itself

Dishler Laser — Sun, 18 Oct 2009 14:40:19 +0100

It was not that long ago that in the American West where we now reside, patients were given something to bite on, like a soft bullet to reduce the pain of surgery. Modern anesthesia has made remarkable advances in that while unconscious patients can be treated oblivious to their surroundings. It is a different matter for LASIK vision correction. Here we need the patient to cooperate and to fixate on a lighted target in order to properly perform the procedures. We also have advanced in that there are eye trackers, all laser procedures, and much improved technology but in the end we require an awake and cooperative patient to perform this procedure. One of the benefits of having a surgery center as opposed to an office environment is that we can confidently give our p...

Bite The Bullet

Dishler Laser — Sat, 17 Oct 2009 14:35:57 +0100

Influence of the Use of Laser Phototherapy (λ660 or 790 nm) on the Survival of Cutaneous Flaps on Diabetic Rats

Photomedicine and Laser Surgery — Thu, 15 Oct 2009 12:25:45 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Martino TV

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Dr. Dishler appears weekly on Martino TV as a vision expert. Martino TV is on channel 31 from 9-10 AM on Tuesday mornings. He is also on Channel 2 from 11AM until noon. Tune in to find out the latest on LASIK. His appearances can be found on the channel 31 website or KDVR Denver. During his first appearance Dr. Dishler explained how LASIK works and what is different about the blade free or all laser LASIK. Video that was taken at his office was shown demonstrating how the procedure is done. On the second appearance June 9th one of Dr. Dishler's patients, Brian, explained his experiences just three weeks before during his procedure and how he now can see better than 20/20 in both eyes. Brian wants to be a pilot in the air force, and his excellent vi...

20/20 vision and what it means in laser vision correction

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

The number which is most familiar to people when we discuss vision is 20/20. This is so much so that there is a television show with this title. 20/20 simply means being able to see at 20 feet what a "normal person" can see at 20 feet. There is a line on the eye chart which signifies this level of vision. Therefore 20/40, the minimum vision to drive, is that vision which can be seen at 20 feet that a "normal person" could see if they were farther away, in fact twice as far at 40 feet. While this is important, and a standard measure of vision, it does not explain all of what is important in vision. For instance, it says nothing about near vision, and in older patients, presbyopia or difficulty seeing at near is a consideration. A...

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Astigmatism First

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Did you ever wonder why almost everyone can hear the same, but so many people don’t see the same? Most people love the sound they hear from an Apple i-Pod™, but many cannot enjoy a movie without their glasses or contact lenses. Somehow, evolution just hasn’t completely perfected vision, at least for many of us. And that is especially true when it comes to astigmatism, the most challenging form of vision imperfection. Astigmatism is when the front of the eye is not round like it is supposed to be. There just isn’t any good reason for an eye to be warped, and we just don’t see this kind of distortion when it comes to ears. Of course vision is a lot more complicated than hearing, and therefore this is understandable. Mayb...

What LASIK costs

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

There are several web sites that track the cost of LASIK procedures by geographic region, by year, and by other metrics. It is surprising how little the costs of this procedure have changed over the last 10 years, and how little it varies between providers. There is a range of costs which are certainly more in places like New York or Los Angeles, but in the midwest including Colorado, these costs are fairly stable. In general LASIK costs between $1000 and $3000 per eye or $2000 to $6000 total. For the quality centers which offer blade free LASIK with state of the art lasers, the average cost is about $2500 per eye or $5000. Our charges are significantly lower than these averages. Some centers market directly to perspective patients with "teaser"...

Choose the Doctor that Doctors choose

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Doctor Dishler began performing LASIK in 1995 as the first doctor in Colorado, and the region to perform LASIK. In 2000 he was the first to perform IntraLASIK, the all blade free LASIK procedure. Over the years we have led in the laser vision correction field, including participation in numerous clinical studies, and being admitted to the organization "Trusted LASIK Surgeons." Throughout this period, most of the patients that have been treated by Dr. Dishler have been referred to him by other doctors in Denver, Centennial, Aurora, and Littleton as well as Highlands Ranch and other areas in metro Denver. Many patients have come from Boulder, Colorado Springs, Loveland, Fort Collins and mountain areas such as Aspen and Grand Junction. Most of these patients ...

Dry Eye

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

The eye is covered in a tear layer, and we all know that tears can be increased with stress, sorrow, or even the wind, sometimes rolling down the cheek in a torrent. The tears both keep the eye clean and also are the critical front optical surface of the eye. What is less appreciated, is that a decrease in tears can actually result in blurred vision. This blurry vision is many times thought to be due to some other problem than a dry eye cause. We have to understand that the tears are actually made of three separate layers. The outer or lipid oil layer slows tear evaporation. The main layer is the liquid layer which is mostly water and some solutes such as sodium which is what makes tears salty. The inner layer which smoothly attaches the tears is a...

Guaranteed Lowest Price

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

There is a perception that if one goes to a large corporate entity, one will get better value than a small boutique individually owned store. While this has proven true for big box stores like Walmart or Home Depot, it is not necessarily true for service based businesses. As an example, large corporate tax preparation entities are not going to be less expensive than your local tax accountant. In the field of medical services, we rarely have to consider cost since most medical care is covered, at least in part, by health insurance. For health care that is outside of that system, we can look at plastic surgery for example and find that the costs for most procedures are fairly constant and the differences are largely due to the reputation of the doctor involved. When i...

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Location, Location, Location

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Denver, Colorado is what we say when people ask where we are located. True, we are not actually within Denver city limits, but we are located at what many believe is the most convenient spot for everyone within the greater Denver metropolitan area to easily come and visit. In normal conditions, you can reach our office within 15-20 minutes from downtown Denver, Cherry Creek, most of Aurora, Centennial, and Highlands Ranch. And within 30 minutes we are from Arvada, Wheatridge and Castle Rock or Denver International Airport. This is because we close to the intersection of all the major freeways in the Denver area. We are virtually on I-25 between I-225 to the north, and I-470 to the south. This means convenient travel from the newly improved highway system...

Measure Twice, Cut Once

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Great results require great data. When we reach the step of applying laser energy to the eye, we are on almost the last step of a checklist that has many steps preceding it. To begin with we must take a careful history of the patient, their vision, and their eye and medical history. We need to understand their visual needs, what they are currently wearing (contact lenses or glasses or nothing) and how effective these have been. Then we want to understand what the patients expectations are with laser vision (ususally LASIK) correction, make sure that they are a suitable candidate mentally and physically for this procedure, and discuss alternatives and options that are available to them. They need to decide whether to have one eye done at a time or both the same...

LASIK -- What does it mean?

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

LASIK is an acronym which means the letters each stand for a word. In this case it is Laser Assisted Stromal In-situ Keratomileusis. This is definitely a mouthful, and when we were in the early 1990's trying to come up with a word describing this procedure, this seemed to make sense. It was preceded by another acronym, ALK, which stood for Automated Lamellar Keratoplasty, and was the non-laser predecessor of the LASIK procedure. We began doing ALK in the early 1990's and this was a procedure where a flap was made with a microkeratome, some tissue was cut using the same microkeratome with some special settings, and the flap was replaced. It worked fairly well, but when lasers came along, it seemed obvious that the increased accuracy of the laser would make this...

Dishler Introduces Latisse

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

We have signed on with Allergan Pharmaceuticals to dispense Latisse for our patients in Denver, Centennial, Aurora and from Colorado Springs and Fort Collins who wish to have longer, thicker, and darker eyelashes. We have received numerous requests from existing patients to offer this product, and although it does not have the "gravity" of LASIK or laser vision correction, it is something that many of our female patients have been requesting. Since Latisse can only be prescribed by medical doctors (MD) and not optometrists (OD) we are also providing this for patients referred by our network of co-managing Optometrists. Tomorrow I am going for my weekly segment on the Tom Martino Show on Channel 31 and channel 2 in Denver, to introduce our Latisse program, and to...

Blade free LASIK is better LASIK

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

LASIK has been a breakthrough in vision correction in that it is quick, virtually pain free and in most cases eliminates the need for glasses or contact lenses. The achilles heel of LASIK was always the first step, making a corneal flap. Here was the non-laser part and in about 50% of cases this technique based on technology that is about 50 years old, is still in use today. Basically a motor driven electric disposable razor blade cuts the cornea to remove the top layers and allows the laser to treat the inner cornea with the flap replaced and in hours the eye is functionally healed and vision is restored. The cutting of this flap is in most cases reliable, but as one can imagine, sometimes there can be problems which include tears, holes, incomplete and mis-created...

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We are Denver LASIK

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

For all of the convenient restaurants and hotels near our office and a map please go here to find more about Denver's first Denver LASIK laser vision correction center. (Source: Dishler Laser)

LASIK alternative: Advanced Surface Ablation

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Patients need to have their individual needs evaluated from both a safety and effectiveness standpoint when considered for laser vision correction surgery. The first laser treatment, and the one that the laser companies thought was going to be the only laser treatment was to treat the front of the eye with the laser and let a new skin or epithelium heal with the eye patched. Although this was the most simple approach, it had several limitations. For one, there was considerable discomfort, and this made it none to popular. There were other problems such as haze or scarring of the cornea, decreased vision, and others. When LASIK came along, as an upgrade to a previous procedure, ALK, it seemed to resolve most of these problems and was quickly adopted as the trea...

Take a tour of the LASIK facility

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

When you visit the Dishler Laser Institute, you will take an elevator to the 12th floor where you will enter to a panoramic view of the Rocky Mountains (we used to be called Laser Institute of the Rockies). You will be greeted by our receptionists/patient counselors who are highly trained to not only get you checked in, but to answer your questions and make you feel at home. You can use your cell phone, our courtesy phone, have a cup of java, and relax in our spacious waiting area. You will be seen by a patient counselor, an ophthalmic technician, and either Dr. Brownfield or Dr. Petraitis during your free screening. You will have some quick an painless diagnostic scans taken of your eyes, answer a few questions about your general and eye health, and see a short vid...

Denver Lasik Blog summer LASIK special

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Contact us at Dishler Laser Institute to learn more about our summer special. Not valid with any other offers. This is definitely the best deal you can get on the most advanced laser vision correction in Denver Colorado and it has brought patients from throughout the region to enjoy this opportunity for better eyesight. If you live anywhere within a few hundred miles of Denver Colorado, you might want to consider this offer. And with financing from either Care Credit or Chase, we have the most competitive rates for vision correction affordability, including no interest financing for 24 months (wac). We also work with hundreds of referring doctors and you can get LASIK or PRK from us at this unbelievable price including your own personal doctor's fees which ar...

What is a femtosecond and why is that important?

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Back in the year 2000 (almost 10 years ago) I was approached by some people that I knew in the vision correction industry and was told that they were working on a new laser which among other things could be a better way to do LASIK. Intrigued, I flew to San Diego and watched Dr. Lee Nordan (now retired) perform some of the first uses of this new device, a femtosecond laser, to make a corneal flap. It was much different than the production devices we have today, slower for one thing, but it did make cornea flaps with light, which was a really neat trick. The company which had just started was called Intralase, and the core of its competence was drawn from scientists and physicists who had worked on this project at the University of Michigan. I became one of the group of th...

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In Denver Colorado for a trusted Lasik surgeon look to "Trusted LASIK Surgeons"

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Trusted LASIK surgeons is an organization that states on their website you must have the following qualifications: Have over 10 years experience and have performed at least 2,000 refractive surgery procedures Offer Intralase ("all-laser") LASIK and Wavefront ("custom") LASIK & PRK Offer complete refractive care, not just LASIK Are leaders in LASIK and refractive surgery research and cataract surgery Have treated other eye surgeons and eye professionals or their families Have treated patients who had problems with a previous LASIK surgery Trusted by the manufacturers of lasers to perform studies to obtain FDA approval Teach and certify other LASIK and re...

LASIK is about how you feel about the world not just how you see it

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

When a patient comes to us or any doctor, we are supposed to not be treating just a complaint or an illness, but rather the whole individual. This means taking into account a broad range of factors that includes not only what brings them to visit with us today, but also, what they are about and where they have been and where they hope to be going in the future. It is much more than taking a reading from their glasses, and then putting them under a laser for a few minutes. We must make a clinical determination if and what would be the best treatment for a particular patient. Also we consider what would suit their particular needs not only now but into the future. Contrary to popular opinion, most of the patients that we treat have significant corrections that w...

What to do when your perfect vision gets blurry at age 40

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

A brief anatomy and optics discussion is needed because this is not really easy to understand. In contrast to nearsightedness where the eye is too long for the corneal shape, in farsightedness the opposite occurs. Light rays want to focus behind the eye rather than on the retina where they belong, and this blurs the vision. Unlike nearsightedness, the youthful eye can overcome this with the lens inside the eye which can focus and overcome this defect in the shape. However, as we age, the lens loses this ability, and things get out of focus. For these eyes this is more true the closer something is that we are looking at, so this is why reading up close is the first thing to go. With LASIK or any of the flavors of laser vision correction (such as PRK), we ...

How is LASIK similar to a Ziploc bag and why should you care?

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Many people do not understand the revolution in vision correction surgery ushered in by LASIK and why it works so well. The eye, like the rest of the body, has a defense mechanism that when anything more than touches us we have response to repel the invader. This is the limitation of PRK, or surface ablation where the outside of the eye is reshaped. The eye shortly after this knows that something drastic has happened and a healing response begins. We can blunt this response with things like mitomycin C (off label) and a contact lens, and other medications, but there is a battle to calm the eye while it heals. LASIK was an evolution from ALK (Automated Lamellar Keratoplasty) where a flap is made and tissue was removed using the same cutting device. Althou...

Relax, the eye trackers are fully engaged

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Modern cameras have image stabilization which can make a jittery photographer take great pictures. Using a similar principle, modern lasers employ eye trackers to "lock on" to reference areas of the eye and makes small movements invisible to the laser which is providing the correction. Many different types of eye trackers have been utilized but most rely on the pupil and use infrared imaging to obtain the high contrast needed for effective tracking. Once the patient is under the laser, and in the case of LASIK, after the flap has been lifted, the eye tracker is engaged and almost instantaneously knows where the pupil is throughout the treatment. If the patient moves their fixation too drastically, the laser will stop until fixation is within a safe range to trea...

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We are so glad that the competition is trying to catch up!

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

Being one of the small handful of doctor/investigators to usher in the femtosecond lasik procedure almost 10 years ago, and with a long period before general acceptance by most of our competitors, I am always amused to notice just how many local "experts" there now are on the all blade free procedure. It was five years before a second Colorado doctor stepped up to this technology, and it was not a center in Denver. Today there are a whole bunch of doctors with a variety of femtosecond lasers, all claiming to be the latest and greatest. Lasers are tools, and a better tool can do a better job. It is equally important that the person who is using that tool understands its application and its limitations. There are private web discussion groups where doctors ...

No one can guarantee you 20/20 vision

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

One thing is for sure about medical procedures, and that is, that nothing is for sure. On rare occasion even relatively trivial procedures can turn into disasters, and most often very complex surgery goes extremely well. Doctors are taught and ethics demands that we cannot promise any result since there are so many variables that such a promise is not reliable. What we can do is show our past experiences in similar cases and there is a good chance that your experience will follow others like you. This is where it is important to ask your doctor not for the experience of dozens of doctors from around the country who pool their numbers and experiences, but rather from your specific doctor in treating others with your specific problem. We at Dishler LASIK have data bas...

Own The Night

Dishler Laser — Wed, 14 Oct 2009 14:59:22 +0100

When laser vision was first conceived, an optical engineer named Dr. Charles Munnerlyn developed a mathematical model for reshaping the front of the eye in the 1980's to correct nearsightedness and he received a patent for his work. I met Dr. Munnerlyn recently and he is still very interested in the field of laser vision correction. His formula was to flatten the cornea the correct amount to achieve a desired result without much emphasis on real world issues such a night vision. As it turned out, this formula worked quite well and was the basis of a company and a laser very familiar to many called VISX. Without delving into a tremendous amount of detail, it became understood over time that although these lasers could correct vision predictably and became FDA approve...

Biomodulative Effects of Visible and IR Laser Light on the Healing of Cutaneous Wounds of Nourished and Undernourished Wistar Rats

Photomedicine and Laser Surgery — Mon, 12 Oct 2009 16:36:35 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Pain Threshold Improvement for Chronic Hyperacusis Patients in a Prospective Clinical Study

Photomedicine and Laser Surgery — Mon, 12 Oct 2009 16:33:41 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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High-Intensity Laser and Photodynamic Therapy as a Treatment for Recurrent Herpes Labialis

Photomedicine and Laser Surgery — Mon, 12 Oct 2009 16:33:38 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Evaluation of Low-Level Laser Therapy with a He–Ne Laser on the Healing of an Osteochondral Defect using a Biomechanical Test

Photomedicine and Laser Surgery — Mon, 12 Oct 2009 16:33:38 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effects of Low-Level Laser Therapy on Pain and Scar Formation after Inguinal Herniation Surgery: A Randomized Controlled Single-Blind Study

Photomedicine and Laser Surgery — Mon, 12 Oct 2009 15:55:57 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Analysis of Low-Level Laser Radiation Transmission in Occlusive Dressings

Photomedicine and Laser Surgery — Fri, 09 Oct 2009 12:01:36 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Green Tea and Red Light—A Powerful Duo in Skin Rejuvenation

Photomedicine and Laser Surgery — Fri, 09 Oct 2009 11:57:51 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Effect of 830 nm Laser Phototherapy on Osteoblasts Grown In Vitro on Biosilicate® Scaffolds

Photomedicine and Laser Surgery — Fri, 09 Oct 2009 11:42:30 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Laser Phototherapy as Topical Prophylaxis Against Radiation-Induced Xerostomia

Photomedicine and Laser Surgery — Fri, 09 Oct 2009 11:42:24 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Semi-Automated method of analysis of horizontal histological sections of skin for objective evaluation of fractional devices

Lasers in Surgery and Medicine — Thu, 08 Oct 2009 23:00:00 +0100

The treatment of skin with fractional devices creates columns of micro-ablation or micro-denaturation depending on the device. Since the geometric profiles of thermal damage depend on the treatment parameters or physical properties of the treated tissue, the size of these columns may vary from a few microns to a few millimeters. For objective evaluation of the damage profiles generated by fractional devices, this report describes an innovative and efficient method of processing and evaluating horizontal sections of skin using a novel software program.Ex vivo porcine skin was treated with the Lux1540/10, Lux1540 Zoom and Lux2940 with 500 optics. Horizontal (radial) sections of biopsies were obtained and processed with H&E and NBTC staining. Digital images of the histologic sections were tak...

Methodological quality of systematic reviews analyzing the use of laser therapy in restorative dentistry

Lasers in Medical Science — Thu, 08 Oct 2009 06:55:48 +0100

Abstract The purpose of this study was to identify systematic reviews (SRs) that compared laser with other dental restorative procedures and to evaluate their methodological quality. A search strategy was developed and implemented for MEDLINE, the Cochrane Library, LILACS, and the Brazilian Dentistry Bibliography (1966–2007). Inclusion criteria were: the article had to be an SR (± meta-analysis); primary focus was the use of laser in restorative dentistry; published in English, Spanish, Portuguese, Italian, German. Two investigators independently selected and evaluated the SRs. The overview quality assessment questionnaire (OQAQ) was used to evaluate methodological quality, and the results were averaged. There were 145 references identified, of which seven were SRs...

Comparison of clinical outcomes of oral erythroleukoplakia treated with photodynamic therapy using either light-emitting diode or laser light

Lasers in Surgery and Medicine — Wed, 07 Oct 2009 23:00:00 +0100

This study tested whether topical ALA-PDT using either the LED or laser light was also an effective treatment modality for oral erythroleukoplakia (OEL) lesions.In this prospective but non-randomized study, 20 OEL lesions were treated with topical ALA-PDT using the 635-nm LED light and 26 OEL lesions were treated with topical ALA-PDT using the 635-nm laser light. The difference in clinical outcomes was compared between the two groups by Fisher exact test.We found that the 20 LED light-treated OEL lesions showed complete response (CR) in 17 and partial response (PR) in 3. The 17 CR OEL lesions required an average of 3.7 (range, 2-7) treatments of ALA-PDT to achieve CR of the lesions. The 26 laser light-treated OEL lesions showed CR in 25 and PR in 1. The 25 CR OEL lesions needed an average ...

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Utilization of excimer laser debulking for critical lesions unsuitable for standard renal angioplasty

Lasers in Surgery and Medicine — Wed, 07 Oct 2009 23:00:00 +0100

We describe early experience with revascularization of critical renal artery lesions deemed unsuitable for standard renal angioplasty. Institutional Review Board permission to conduct the data analysis was obtained.Among 130 percutaneous renal artery interventions with balloon angioplasty and adjunct stenting, there were 12 (9%) patients who underwent laser debulking prior to stenting. These patients presented with critical (95±3.5% stenoses) lesions (11 de novo, 1 stent restenosis) deemed unsuitable for standard renal angioplasty because of marked eccentricity and presence of thrombus. Indications for intervention included preservation of kidney function, treatment of uncontrolled hypertension, management of congestive heart failure, and treatment of unstable angina. Blood pressure and e...

The Effect of Laser Irradiation on Proliferation of Human Breast Carcinoma, Melanoma, and Immortalized Mammary Epithelial Cells

Photomedicine and Laser Surgery — Wed, 07 Oct 2009 15:27:00 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Venous Lake of the Lips Treated Using Photocoagulation with High-Intensity Diode Laser

Photomedicine and Laser Surgery — Wed, 07 Oct 2009 15:23:18 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

A Comparative Study of the Effects of Ab Externo Superpulse Carbon Dioxide Laser-Assisted Trabeculectomy with Conventional Trabeculectomy in Rabbits

Photomedicine and Laser Surgery — Wed, 07 Oct 2009 15:19:55 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effectiveness of 980-mm Diode and 1064-nm Extra-Long-Pulse Neodymium-Doped Yttrium Aluminum Garnet Lasers in Implant Disinfection

Photomedicine and Laser Surgery — Wed, 07 Oct 2009 15:15:47 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Financing Aesthetic Services

Aesthetic Lasers — Mon, 05 Oct 2009 15:14:17 +0100

Patients can have bigger dreams when you break costs into smaller pieces. When the economy is down, people tend to cut cosmetic procedures from their budgets, as they see it as a “want” instead of a “need.” For doctors this can mean fewer procedures in their practices. There are many credit card based financial products that [...]Post from: Aesthetic Laser OffersFinancing Aesthetic Services (Source: Aesthetic Lasers)

Acid Resistance and Structural Changes of Human Dental Enamel Treated with Er:YAG Laser

Photomedicine and Laser Surgery — Mon, 05 Oct 2009 14:44:52 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Diode Laser Decreases the Activity of Catalase on Submandibular Glands of Diabetic Rats

Photomedicine and Laser Surgery — Mon, 05 Oct 2009 14:37:52 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Comparative Study of Wavelengths for Laser Lipolysis

Photomedicine and Laser Surgery — Mon, 05 Oct 2009 14:37:52 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Molecular Perspectives of Wound Healing - Cellular Models

Photomedicine and Laser Surgery — Mon, 05 Oct 2009 14:10:03 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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The Effects of 660 nm and 780 nm Laser Irradiation on Viability of Random Skin Flap in Rats

Photomedicine and Laser Surgery — Mon, 05 Oct 2009 14:10:03 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

The influence of erbium:yttrium–aluminum–garnet laser ablation with variable pulse width on morphology and microleakage of composite restorations

Lasers in Medical Science — Sun, 04 Oct 2009 05:42:17 +0100

The objective of this study was to evaluate the influence of various pulse widths with different energy parameters of erbium:yttrium–aluminum–garnet (Er:YAG) laser (2.94 μm) on the morphology and microleakage of cavities restored with composite resin. Identically sized class V cavities were prepared on the buccal surfaces of 54 bovine teeth by high-speed drill (n = 6, control, group 1) and prepared by Er:YAG laser (Fidelis 320A, Fotona, Slovenia) with irradiation parameters of 350 mJ/ 4 Hz or 400 mJ/2 Hz and pulse width: group 2, very short pulse (VSP); group 3, short pulse (SP); group 4, long pulse (LP); group 5, very long pulse (VLP). All cavities were filled with composite resin (Z-250-3 M), stored at 37°C in distilled water, polished after 2...

Monitoring interstitial m-THPC-PDT in vivo using fluorescence and reflectance spectroscopy

Lasers in Surgery and Medicine — Fri, 02 Oct 2009 23:00:00 +0100

In order to understand the mechanisms of photodynamic therapy (PDT) it is important to monitor parameters during illumination that yield information on deposited PDT dose. The aim of this study is to investigate the possibility of monitoring implicit parameters, such as photobleaching, in addition to monitoring explicit parameters (fluence (rate), oxygenation, photosensitizer concentration) directly or indirectly. These parameters are monitored during PDT without interrupting the therapeutic illumination.Rats were injected with 0.3 mg kg-1 m-THPC. Sixteen hours after administration the abdominal muscle in rats was irradiated for 1,500 seconds using clinically relevant fluence rates of 50, 100, and 250 mW cm-1 of diffuser length at 652 nm. In addition to the linear diffuser for delivering t...

OB/GYNs and Laser Hair Removal

Aesthetic Lasers — Fri, 02 Oct 2009 14:33:59 +0100

Some people wonder why OB/GYN practices offer LHR. Isn’t it the realm of plastic surgeons and dermatologists? For gynecologists laser hair removal is a natural transition and a perfect fit as they can perform these procedures in discrete areas of the female body in a comfortable setting of a medical office. Permanent reduction of hair in [...]Post from: Aesthetic Laser OffersOB/GYNs and Laser Hair Removal (Source: Aesthetic Lasers)

Choosing Laser Can Be Daunting

Aesthetic Lasers — Fri, 02 Oct 2009 14:18:54 +0100

Doctors Arielle N. B. Kauvar from New York Laser & Skin Care and E. Victor Ross, M.D., director of laser and cosmetic dermatology, Scripps Clinic, San Diego, provided a quick overview of different aesthetic lasers for medical practice in this article published by Modern Medicine yesterday. The overview is a good basic briefing on most of [...]Post from: Aesthetic Laser OffersChoosing Laser Can Be Daunting (Source: Aesthetic Lasers)

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Effect of Titanium Tetrafluoride and Amine Fluoride Treatment Combined with Carbon Dioxide Laser Irradiation on Enamel and Dentin Erosion

Photomedicine and Laser Surgery — Fri, 02 Oct 2009 01:45:56 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effect of the Nd:YAG and the Er:YAG Laser on the Adhesive–Dentin Interface: A Scanning Electron Microscopy study

Photomedicine and Laser Surgery — Fri, 02 Oct 2009 01:33:24 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Er:YAG Laser Ablation of Bone in Experimental Diabetics

Photomedicine and Laser Surgery — Fri, 02 Oct 2009 01:31:21 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effects of 780-nm Low-level Laser Therapy with a Pulsed Gallium Aluminum Arsenide Laser on the Healing of a Surgically Induced Open Skin Wound of Rat

Photomedicine and Laser Surgery — Fri, 02 Oct 2009 01:29:18 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Salivary Levels of TNF-α and IL-6 in Patients with Denture Stomatitis Before and After Laser Phototherapy

Photomedicine and Laser Surgery — Fri, 02 Oct 2009 01:27:00 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Effect of Low-Level Laser Irradiation on Bisphosphonate-Induced Osteonecrosis of the Jaws: Preliminary Results of a Prospective Study

Photomedicine and Laser Surgery — Fri, 02 Oct 2009 00:07:35 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Poly (N-Isopropylacrylamide)-Coated Multifunctional Nanoparticles for Cell Tracking

Photomedicine and Laser Surgery — Fri, 02 Oct 2009 00:05:14 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Novel wavelengths for laser nerve stimulation

Lasers in Surgery and Medicine — Thu, 01 Oct 2009 23:00:00 +0100

This study investigated alternative wavelengths for nerve stimulation.The sciatic nerves of rats were irradiated with four different lasers - a Ho:YAG (2100 nm), a Yb:glass fiber laser (1495 nm) and diode lasers (1450 nm and 1540 nm).All lasers evoked a visible leg twitch response, and electromyography confirmed muscle activation. The Yb:glass laser at 1495 nm delivered through a single mode fiber was found to be the most effective stimulus. The stimulation threshold for a 2 millisecond pulse from the Yb:glass laser was determined to be 3.7±2.8 mJ/cm2.The Yb:glass laser has the potential for use in neurostimulation, as an alternative to electrical stimulation. Lasers Surg. Med. © 2009 Wiley-Liss, Inc. (Source: Lasers in Surgery and Medicine)

Ablation of articular cartilage with an erbium:YAG laser: An ex vivo study using porcine models under real conditions - ablation measurement and histological examination

Lasers in Surgery and Medicine — Thu, 01 Oct 2009 23:00:00 +0100

The use of an erbium:YAG laser in arthroscopic surgery has the advantage of a precise treatment of soft tissue. Due to the high absorption in water, the laser energy is perfectly matched to smoothing the hydrous, fibrillated articular cartilage surface. In minimal invasive surgery, the workspace is filled with aqueous liquids for enlargement. This appears contrary to the absorption characteristics of erbium:YAG laser radiation in water. The purpose of this study was to evaluate the ablated volume per pulse of cartilage lesions and the potential side effects including thermal damage and tissue necrosis.Twenty-four osteochondral specimens of porcine knee joints were irradiated with an Er:YAG laser completely submerged in water, with distances to the cartilage surface of 1, 3 and 5 mm and pul...

Simulations of measured photobleaching kinetics in human basal cell carcinomas suggest blood flow reductions during ALA-PDT

Lasers in Surgery and Medicine — Thu, 01 Oct 2009 23:00:00 +0100

In a recently completed pilot clinical study at Roswell Park Cancer Institute, patients with superficial basal cell carcinoma (sBCC) received topical application of 20% 5-aminolevulinic acid (ALA) and were irradiated with 633 nm light at 10-150 mW cm-2. Protoporphyrin IX (PpIX) photobleaching in the lesion and the adjacent perilesion normal margin was monitored by fluorescence spectroscopy. In most cases, the rate of bleaching slowed as treatment progressed, leaving a fraction of the PpIX unbleached despite sustained irradiation. To account for this feature, we hypothesized a decrease in blood flow during ALA-photodynamic therapy (PDT) that reduced the rate of oxygen transported to the tissue and therefore attenuated the photobleaching process. We have performed a detailed analysis of this...

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Comparison of Nd:YAG Lasers to IPL Devices

Aesthetic Lasers — Wed, 30 Sep 2009 14:27:44 +0100

YAG 1064 nm Lasers Intense Pulsed Light (IPL) Devices Applications Hair Removal, Photorejuvenation, Skin Tightening, Active Acne treatment, Telangiectasias (spider veins), Rosacea, Sun & Age Spots, Pseudofolliculitis Barbae. Hair Removal, Photorejuvenation, Sun & Age Spots, Rosacea. Efficacy High power to dermis: more energy to follicles, vessels, collagen, sebaceous glands. High power absorption in epidermis: less energy to deep dermal structures. Comfort Less painful due [...]Post from: Aesthetic Laser OffersComparison of Nd:YAG Lasers to IPL Devices (Source: Aesthetic Lasers)

Assessment of a sheep animal model to optimise photodynamic therapy in the oesophagus

Lasers in Surgery and Medicine — Tue, 29 Sep 2009 23:00:00 +0100

In conclusion, this model showed many similarities with humans as to mTHPC's plasma and tissue pharmacokinetics, and for tissue PDT response, making it suitable to optimise oesophagus PDT. Lasers Surg. Med. © 2009 Wiley-Liss, Inc. (Source: Lasers in Surgery and Medicine)

Gingival curettage study comparing a laser treatment to hand instruments

Lasers in Medical Science — Tue, 29 Sep 2009 16:56:04 +0100

Abstract The purpose of this clinical study was to examine nonsurgical treatments of periodontal disease comparing a diode laser to subgingival curettage with conventional hand instruments. The study group comprised 18 patients with moderate periodontal degradation who were treated without local anesthesia. Each quadrant was randomly allocated in a split-mouth design either to treatment with a 810-nm diode laser using an energy of 2 W (test group) or to gingival curettage using hand instruments (control group). Clinical data, including plaque index (PI), gingival index (GI), sulcus bleeding index (SBI), pocket depth (PD), clinical attachment level (CAL) and visual analog scale (VAS) score were acquired prior to and 4 weeks after treatment. The treatment time for ...

Fractional photothermolysis—an update

Lasers in Medical Science — Tue, 29 Sep 2009 07:33:03 +0100

Abstract The novel concept of non-ablative fractional photothermolysis was introduced to the market in 2003 as an answer to the need for effective, yet low risk, resurfacing techniques. Unlike conventional ablative and non-ablative lasers, fractional ablative and non-ablative photothermolysis treats only a fraction of the skin, leaving up to a maximum of 95% of the skin uninvolved. The undamaged surrounding tissue allows for a reservoir of viable tissue, permitting rapid epidermal repair. Non-ablative fractional photothermolysis is currently approved by the US Food and Drug Administration (FDA) for the treatment of pigmented lesions, periorbital rhytides, skin resurfacing, melasma and soft tissue coagulation, acne and surgical scars, and actinic keratoses. However, its off...

In situ and in vitro comparison of laser fluorescence with visual inspection in detecting occlusal caries lesions

Lasers in Medical Science — Tue, 29 Sep 2009 01:06:08 +0100

Abstract The aim of this study was to compare the in situ and in vitro performances of a laser fluorescence (LF) device (DIAGNOdent 2095) with visual inspection for the detection of occlusal caries in permanent teeth. Sixty-four sites were selected, and visual inspection and LF assessments were carried out, in vitro, three times by two independent examiners, with a 1-week interval between evaluations. Afterwards, the occlusal surfaces were mounted on the palatal portion of removable acrylic orthodontic appliances and placed in six volunteers. Assessments were repeated and validated by histological analysis of the tooth sections under a stereomicroscope. For both examiners, the highest intra-examiner values were observed for the visual inspection when in vitro and in situ e...

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Visible light induces no formation in sperm and endothelial cells

Lasers in Surgery and Medicine — Mon, 28 Sep 2009 23:00:00 +0100

Visible light-based stimulation using low-intensity lasers, LEDs, and broadband visible light devices has been recently introduced for therapy of human tissues in the absence of exogenous photosensitizers. Nitric oxide (NO) formation might be a potential mechanism for photobiomodulation because it is synthesized in cells by nitric oxide synthase (NOS), which contains both flavin and heme groups that absorb visible light. NO synthesis may also result from increased reactive oxygen species (ROS), which are found in various cell cultures following visible light illumination. NO is mainly known for inducing blood vessel dilation by endothelial cells, and in sperm cells NO is considered as an important agent in acrosome reaction and capacitation process, which are essential for successful ferti...

Metallo-naphthalocyanines as photothermal sensitisers for experimental tumours: In Vitro and in vivo studies

Lasers in Surgery and Medicine — Mon, 28 Sep 2009 23:00:00 +0100

This study aims to investigate the molecular features of the photosensitiser which optimise the photothermal activity.Two octabutoxy-naphthalocyanines centrally coordinated with Pd(II) or Pt(II) ions were prepared by chemical synthesis and tested for their affinity and photothermal sensitisation activity toward a selected tumour cell line, namely B78H1 amelanotic melanoma. Irradiations were performed by using a Ti:sapphire laser operated in a pulsed regime (10 Hz, 30 nanosecond pulses, 120 mJ) at 809 nm (Pt) or 826 nm (Pd). The subcellular distribution pattern of the photosensitiser was also assessed by optical microscopy, while the nature of the photoinduced cell damage was determined by scanning electron microscopy. The results thus obtained provided a basis for subsequent in vivo studie...

Dangers of Spa Hopping

Aesthetic Lasers — Fri, 25 Sep 2009 22:02:11 +0100

We stumbled upon an old (March 7, 2007) article in ABC News – Spa Left Woman With Skin ‘Like Raw Meat’ – a story about a 52-year-old stay-at-home mom who saw the ugly side of medical spas. She went to one in Panama City, Fla., for what she thought was a routine procedure – laser [...]Post from: Aesthetic Laser OffersDangers of Spa Hopping (Source: Aesthetic Lasers)

Anti-Inflammatory Effect of Low-Level Laser and Light-Emitting Diode in Zymosan-Induced Arthritis

Photomedicine and Laser Surgery — Fri, 25 Sep 2009 12:42:46 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Influence of Aluminum Oxide Sandblasting Associated with Nd:YAG or Er:YAG Lasers on Shear Bond Strength of a Feldspathic Ceramic to Resin Cements

Photomedicine and Laser Surgery — Fri, 25 Sep 2009 12:34:52 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Root Surface Biomodification with an Er:YAG Laser for the Treatment of Gingival Recession with Subepithelial Connective Tissue Grafts

Photomedicine and Laser Surgery — Fri, 25 Sep 2009 12:29:33 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Photodynamic Therapy in Planktonic and Biofilm Cultures of Aggregatibacter actinomycetemcomitans

Photomedicine and Laser Surgery — Fri, 25 Sep 2009 12:25:04 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

The Basics of the Fractional Technology

Aesthetic Lasers — Thu, 24 Sep 2009 15:38:06 +0100

Why the newer fractional technologies are so popular? The latest fractional laser technologies offer a better balance of efficacy, patient tolerance and lack of side effects compared to older lasers. For better results the depth of the laser beam penetration and the depth of skin resurfacing are important. But even more important is an optimal combination of [...]Post from: Aesthetic Laser OffersThe Basics of the Fractional Technology (Source: Aesthetic Lasers)

Energy output reduction and surface alteration of quartz and sapphire tips following Er:YAG laser contact irradiation for tooth enamel ablation

Lasers in Surgery and Medicine — Wed, 23 Sep 2009 23:00:00 +0100

This study examined the changes in energy output and surface condition of quartz and sapphire contact tips after Er:YAG laser contact irradiation for tooth enamel ablation.Ten sets of unused quartz or sapphire contact tips were employed for contact irradiation to sound enamel of extracted teeth. The teeth were irradiated with Er:YAG laser at approximately 75 J/cm2/pulse and 20 Hz under water spray for 60 minutes. The energy output was measured before and every 5 minutes after irradiation, and the changes in morphology and chemical composition of the contact surface were analyzed.The energy output significantly decreased with time in both tips. The energy output from the sapphire tips was generally higher on average than that of the quartz. The contact surfaces of all the used quartz tips w...

Laser Skin Resurfacing and Chemical Peels

Aesthetic Lasers — Wed, 23 Sep 2009 15:15:45 +0100

CO2 and Erbium laser skin resurfacing is a very efficient procedure to remove wrinkles, acne scars, blemishes, growths, and sun-damaged skin blemishes. The laser allows the body to produce new collagen and generate new skin. The result is usually “years younger” skin. Improvement continues as the aged and sun-damaged deep collagen areas continue to regenerate [...]Post from: Aesthetic Laser OffersLaser Skin Resurfacing and Chemical Peels (Source: Aesthetic Lasers)

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In Vivo Effects on the Expression of Vascular Endothelial Growth Factor-A165 Messenger Ribonucleic Acid of an Infrared Diode Laser Associated or Not with a Visible Red Diode Laser

Photomedicine and Laser Surgery — Tue, 22 Sep 2009 13:13:44 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Long-Term Hair Removal Results with a Novel Nd:YAG Laser

Aesthetic Lasers — Tue, 22 Sep 2009 02:39:25 +0100

A White Paper by David J. Friedman, MD I recently completed a clinical study of laser hair removal using the LightPod Neo, a 1064nm Nd:YAG laser from Aerolase. I was requested to conduct this study because I have a well established cosmetic dermatology practice in which I perform the laser treatments myself, and hair removal is [...]Post from: Aesthetic Laser OffersLong-Term Hair Removal Results with a Novel Nd:YAG Laser (Source: Aesthetic Lasers)

What Lasers Offer for Pigmented and Spotted Skin

Aesthetic Lasers — Mon, 21 Sep 2009 20:41:24 +0100

Treatment of pigmentation is a complex subject. Determining the type of lesion will help to establish which laser or light device to use and what parameters to set. Hyperpigmentation is a broad descriptive term, offering us little information about etiology or pathophysiology of the lesion. Dividing this expansive category into primary versus secondary helps with treatment decision-making [...]Post from: Aesthetic Laser OffersWhat Lasers Offer for Pigmented and Spotted Skin (Source: Aesthetic Lasers)

Noteworthy Facts About Your Skin

Aesthetic Lasers — Mon, 21 Sep 2009 19:30:17 +0100

1. It’s your body’s largest organ: an average adult’s skin spans 21 square feet, weighs 9 pounds and contains more than 11 miles of blood vessels. 2. The skin releases as much as 3 gallons of sweat a day in hot weather. The areas that don’t sweat are the nail bed, the margins of the lips, [...]Post from: Aesthetic Laser OffersNoteworthy Facts About Your Skin (Source: Aesthetic Lasers)

The Effect of Irradiance Level in 980-nm Diode Laser Skin Welding

Photomedicine and Laser Surgery — Mon, 21 Sep 2009 10:09:50 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Use of 660-nm Diode Laser in the Prevention and Treatment of Human Oral Mucositis Induced by Radiotherapy and Chemotherapy

Photomedicine and Laser Surgery — Mon, 21 Sep 2009 09:58:39 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Laser Therapy in the Tissue Repair Process: A Literature Review

Photomedicine and Laser Surgery — Mon, 21 Sep 2009 09:58:37 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Analysis of Permeability and Morphology of Root Canal Dentin After Er,Cr:YSGG Laser Irradiation

Photomedicine and Laser Surgery — Mon, 21 Sep 2009 09:53:21 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effect of Low-Level Laser Therapy with Output Power of 30 mW and 60 mW in the Viability of a Random Skin Flap

Photomedicine and Laser Surgery — Mon, 21 Sep 2009 09:48:50 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Low-Level Laser Irradiation (InGaAlP-660 nm) Increases Fibroblast Cell Proliferation and Reduces Cell Death in a Dose-Dependent Manner

Photomedicine and Laser Surgery — Mon, 21 Sep 2009 09:30:06 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Combination 830-nm and 633-nm Light-Emitting Diode Phototherapy Shows Promise in the Treatment of Recalcitrant Psoriasis: Preliminary Findings

Photomedicine and Laser Surgery — Mon, 21 Sep 2009 09:30:04 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Evaluation of the furcation area permeability of deciduous molars treated by neodymium:yttrium–aluminum–garnet laser or adhesive

Lasers in Medical Science — Thu, 17 Sep 2009 23:28:33 +0100

Abstract The purpose of this in vitro study was to compare the effects of a self-etch adhesive system and neodymium:yttrium–aluminum–garnet (Nd:YAG) laser application on the dentinal permeability of the furcation area of primary molars. After endodontic access, 39 extracted human deciduous molars were divided into three groups: control group (CG), no treatment; adhesive group (AG), self-etching adhesive was applied to the furcation area; laser group (LG), specimens were irradiated with Nd:YAG laser. To evaluate dentin permeability of the furcation area, we immersed the specimens in 0.5 % methylene blue dye for 4 h. Then, they were longitudinally sectioned into two halves and photographed. The images were analyzed by two qualified evaluators using TpsDig software t...

Preliminary results on the use of a noninvasive instrument for the evaluation of the depth of pigmented skin lesions: numerical simulations and experimental measurements

Lasers in Medical Science — Thu, 17 Sep 2009 23:28:28 +0100

Abstract The early detection of cutaneous pigmented lesions is an important aid to the clinician in recognizing malignant melanoma. In an attempt to correlate the depth of a pigmented skin lesion with its malignant potential, phantoms able to simulate the diffuse reflectance of some lesions of different thicknesses were manufactured and tested to validate a diagnostic instrument developed in-house. Such optical skin-tissue phantoms may be useful for accelerating and optimizing the diagnosis of suspicious lesions of the skin. In fact, benign melanocytic lesions are different in terms of their diffuse reflectance from melanoma. The diffuse reflectance of pigmented skin lesions depends on the amount and distribution of the absorbing/diffusing chromophores embedded in the skin...

Apoptosis- and necrosis-induced changes in light attenuation measured by optical coherence tomography

Lasers in Medical Science — Tue, 15 Sep 2009 21:41:13 +0100

Abstract Optical coherence tomography (OCT) was used to determine optical properties of pelleted human fibroblasts in which necrosis or apoptosis had been induced. We analysed the OCT data, including both the scattering properties of the medium and the axial point spread function of the OCT system. The optical attenuation coefficient in necrotic cells decreased from 2.2 ± 0.3 mm−1 to 1.3 ± 0.6 mm−1, whereas, in the apoptotic cells, an increase to 6.4 ± 1.7 mm−1 was observed. The results from cultured cells, as presented in this study, indicate the ability of OCT to detect and differentiate between viable, apoptotic, and necrotic cells, based on their attenuation coefficient. This functional supplement to high-resolution OCT imaging can be ...

Advantages and esthetic results of erbium, chromium:yttrium–scandium–gallium–garnet laser application in second-stage implant surgery in patients with insufficient gingival attachment: a report of three cases

Lasers in Medical Science — Tue, 15 Sep 2009 21:41:12 +0100

We report on three patients with implants in the anterior area who were operated on under the above conditions. Traditionally, the tissue overlying the implants is removed and eliminated. In seeking a way to preserve the attached gingiva, we raised a trapezoidal flap, uncovering each implant and allowing apical repositioning and transpositioning of keratinized gingiva to the buccal side. The results obtained were compared with those from other patients operated on by conventional scalpel. The erbium, chromium:yttrium–scandium–gallium–garnet (Er,Cr:YSGG) laser minimized postoperative pain, and the time to prosthetic rehabilitation was also shortened. The esthetic results were far superior, and no complications were recorded. Content Type Journal ArticleCategory Brief ReportDO...

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Biophoton Detection and Low-Intensity Light Therapy: A Potential Clinical Partnership

Photomedicine and Laser Surgery — Tue, 15 Sep 2009 19:47:16 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

The Effect of Low-Level Laser Therapy on Healing of Skin Incisions Made Using a Diode Laser in Diabetic Rats

Photomedicine and Laser Surgery — Tue, 15 Sep 2009 19:34:11 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effects of Laser Photobiomodulation on Cutaneous Wounds Treated with Mitomycin C: A Histomorphometric and Histological Study in a Rodent Model

Photomedicine and Laser Surgery — Fri, 11 Sep 2009 12:49:11 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Comparison of Diode Laser and Er:YAG Lasers in the Treatment of Ankyloglossia

Photomedicine and Laser Surgery — Fri, 11 Sep 2009 11:58:24 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

The Effect of Equal Daily Dose Achieved by Different Power Densities of Low-Level Laser Therapy at 635 and 670 nm on Wound Tensile Strength in Rats: A Short Report

Photomedicine and Laser Surgery — Fri, 11 Sep 2009 11:53:05 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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In Vivo Comparison of Simple and Double-Fractionated Low-Level Laser Irradiation Schemes on the Healing of Rat Skin Lesions

Photomedicine and Laser Surgery — Fri, 11 Sep 2009 11:50:43 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Helium-Neon Laser Reduces the Inflammatory Process of Arthritis

Photomedicine and Laser Surgery — Thu, 10 Sep 2009 23:59:10 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Bond Strength of an Etch-and-Rinse Adhesive to KrF Excimer Laser-Treated Dentin

Photomedicine and Laser Surgery — Thu, 10 Sep 2009 23:56:18 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Randomized controlled trial: Comparative efficacy for the treatment of facial telangiectasias with 532 nm versus 940 nm diode laser

Lasers in Surgery and Medicine — Thu, 10 Sep 2009 23:00:00 +0100

While the 532 nm wavelength has been demonstrated to be effective for facial telangiectasias, 940 nm is a novel wavelength which has only been reported in case reports. While both the 532 and 940 nm wavelengths are effective for facial telangiectasias, we lack evidence to support whether one wavelength is superior.Randomized, blinded split-faced trial for the 532 and 940 nm diode laser wavelengths. Side effects of erythema, crusting, swelling, and blistering (0-5 scale, 0 = not present, 1 = trace, 5 = severe) were assessed. Prior to treatment and at 2 months after a series of two treatments, telangiectasias were assessed (1-10 scale, 1 = focal telangiectasias, 10 = diffuse telangiectasias). Assessment of the degree of improvement in facial telangiectasias was performed by two blinded non-t...

Pulsed dye laser-induced inflammatory response and extracellular matrix turnover in rat vocal folds and vocal fold fibroblasts

Lasers in Surgery and Medicine — Wed, 09 Sep 2009 23:00:00 +0100

In this study, we examined the inflammatory and ECM modulating effects of PDL irradiation on normal vocal fold tissues and cultured vocal fold fibroblasts (VFFs).We evaluated the effects of 585 nm PDL irradiation on inflammatory cytokine and collagen/collagenase gene transcription in normal rat vocal folds in vivo (3-168 hours following delivery of [sim]39.46 J/cm2 fluence) and VFFs in vitro (3-72 hours following delivery of 4.82 or 9.64 J/cm2 fluence). We also examined morphological vocal fold tissue changes 3 hours, 1 week, and 1 month post-irradiation.PDL irradiation altered inflammatory cytokine and procollagen/collagenase expression at the transcript level, both in vitro and in vivo. Additionally, PDL irradiation induced an inflammatory repair process in vivo that was completed by 1 m...

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Ablative Potential of the Erbium–Doped Yttrium Aluminium Garnet Laser and Conventional Handpieces: A Comparative Study

Photomedicine and Laser Surgery — Fri, 04 Sep 2009 15:39:24 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Effects of ablative 10,600-nm carbon dioxide fractional laser therapy on suppurative diseases of the skin: A case series of 12 patients

Lasers in Surgery and Medicine — Thu, 03 Sep 2009 23:00:00 +0100

We have used an ablative 10,600-nm carbon dioxide fractional laser system (CO2 FS) for suppurative diseases in order to attempt improvement. The purpose of our study was to demonstrate the effect of CO2 FS on the course of inflammatory reactions in suppurative diseases.We reviewed a total of 12 Korean patients with suppurative diseases of the skin who had a history of treatment failure with several therapeutic modalities as well as active and multiple inflammatory lesions at the time of CO2 FS treatment.Improvement scores considering the number of suppurative lesions revealed that 3 of the 12 patients demonstrated clinical improvement of grade 4. Seven had clinical improvement of grade 3 and two showed improvement of grade 2. Improvement scores in severity were also evaluated; 2 of the 12 ...

In vivo study of age-related changes in the optical properties of the skin

Lasers in Medical Science — Thu, 03 Sep 2009 06:32:25 +0100

Abstract The optical properties of the skin (absorption coefficient, scattering coefficient, refractive index) may serve to characterize the skin and are important for correct light dosimetry in many optical diagnostic procedures and laser treatments especially photodynamic therapy and laser therapy. We determined in vivo the optical properties of tissues near the wrist, elbow and knee in subjects of different ages using diffuse reflectance spectroscopy, having in view the establishment of laser system types for the laser treatment of posttraumatic lesions in subjects of different ages. Diffuse reflection of light from biological tissue is due to the variation in refractive index of tissular and cellular components and the surrounding medium and depends on the wavelength o...

In vitro investigation of intra-canal dentine–laser beam interaction aspects: II. Evaluation of ablation zone extent and morphology

Lasers in Medical Science — Thu, 03 Sep 2009 06:32:24 +0100

Abstract Laser endodontic tips appear to provide a promising alternative to available treatment modalities in the field of endodontology. With the shortcomings in published results regarding the intra-canal behavioural aspects of those tips, it was the aim of this study to investigate the extent of the intra-canal ablation zone and the pattern associated with those tips. Ninety intact extracted bovine teeth were used to prepare mid-root testing cylinders. The samples were divided into three groups (A, B, C), corresponding to the tip diameters. Each group was further subdivided to be irradiated at three different power settings (1500 mW, 1750 mW, 2000 mW) with an erbium, chromium:yttrium–scandium–gallium–garnet (Er,Cr:YSGG) laser with a 65% water to 35%...

Blood flow dynamics after laser therapy of port wine stain birthmarks

Lasers in Surgery and Medicine — Wed, 02 Sep 2009 23:00:00 +0100

The objective of this study was to use objective feedback to assess the acute vascular response to laser therapy.A clinic-friendly laser speckle imaging (LSI) instrument was developed to provide the clinician with real-time images of blood flow during laser therapy. Images were acquired from patients undergoing laser therapy of PWS birthmarks at Scripps Clinic and the Beckman Laser Institute and Medical Clinic. Blood flow maps were extracted from the acquired imaging data. Histogram-based analysis was applied in grading the degree of heterogeneity present in the blood flow maps after laser therapy.Collectively, two types of patient responses were observed in response to laser exposure: (1) an immediate increase in perfusion within minutes after laser therapy; and (2) an overall decrease in...

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Effect of cluster multi-diode light emitting diode therapy (LEDT) on exercise-induced skeletal muscle fatigue and skeletal muscle recovery in humans

Lasers in Surgery and Medicine — Wed, 02 Sep 2009 23:00:00 +0100

In this study we wanted to test if light emitting diode therapy (LEDT) can alter muscle performance, fatigue development and biochemical markers for skeletal muscle recovery in an experimental model of biceps humeri muscle contractions.Ten male professional volleyball players (23.6 [SD ±5.6] years old) entered a randomized double-blinded placebo-controlled crossover trial. Active cluster LEDT (69 LEDs with wavelengths 660/850 nm, 10/30 mW, 30 seconds total irradiation time, 41.7 J of total energy irradiated) or an identical placebo LEDT was delivered under double-blinded conditions to the middle of biceps humeri muscle immediately before exercise. All subjects performed voluntary biceps humeri contractions with a workload of 75% of their maximal voluntary contraction force (MVC) until exh...

Is a vein filled with blood a good model for studying endovenous laser ablation?

Lasers in Surgery and Medicine — Wed, 02 Sep 2009 23:00:00 +0100

No. Abstract. (Source: Lasers in Surgery and Medicine)

The effects of ultra low fluence rate single and repetitive photodynamic therapy on glioma spheroids

Lasers in Surgery and Medicine — Wed, 02 Sep 2009 23:00:00 +0100

Achieving local control of gliomas with photodynamic therapy (PDT) requires the delivery of adequate light fluences to depths of 1-2 cm in the resection margin where the majority of local recurrences originate. This is clinically impractical with current single-shot, intraoperative PDT treatments due to the length of time required to deliver adequate fluences. Multiple or extended treatment protocols would therefore seem to be required. The response of human glioma spheroids to 5-aminolevulinic acid (ALA)-mediated PDT using single or, repetitive light delivery protocols was investigated at both low and ultra low fluence rates.Human glioma spheroids (400 µm diameter) were subjected to sub-threshold light fluence (1.5, 3, or 6 J cm-2) ALA-PDT consisting of four light delivery schemes: singl...

The Effects of Light-Emitting Diode Irradiation at 610 nm and 710 nm on Murine T-Cell Subset Populations

Photomedicine and Laser Surgery — Sat, 29 Aug 2009 21:12:53 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)