MedWorm: OBGYN Top 20

Near-miss maternal mortality: cardiac dysfunction as the principal cause of obstetric intensive care unit admissions.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:43:50 +0100

CONCLUSION: : In this obstetric population, the leading reason for ICU admissions was cardiac disease. The increasing prevalence of advanced maternal age, congenital heart disease, obesity, diabetes, and hypertension among women who are of childbearing age may be contributing factors. LEVEL OF EVIDENCE: : III. PMID: 22270275 [PubMed - in process] (Source: Obstetrics and Gynecology)

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Proteomics Analysis of Plasma for Early Diagnosis of Endometriosis.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:43:08 +0100

CONCLUSION:: A noninvasive test using proteomic analysis of plasma samples obtained during the menstrual phase enabled the diagnosis of endometriosis undetectable by ultrasonography with high sensitivity and specificity. LEVEL OF EVIDENCE:: II. PMID: 22270279 [PubMed - as supplied by publisher] (Source: Obstetrics and Gynecology)

Adjuvant bevacizumab could delay ovarian cancer progression

MedWire News - Ob/Gyn — Mon, 09 Jan 2012 03:39:41 +0100

Treatment with bevacizumab as an addition to standard chemotherapy could delay the progression of advanced epithelial ovarian cancer, two studies in The New England Journal of Medicine suggest. (Source: MedWire News - Ob/Gyn)

Maternal cardiac disease: update for the clinician.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:41:37 +0100

Authors: Simpson LL Abstract Heart disease complicates more than 1% of pregnancies and is now the leading cause of indirect maternal deaths. The spectrum and severity of heart disease observed in reproductive-aged women is changing. Today, congenital heart disease accounts for more than half of cardiac disease in pregnancy, and ischemic heart disease is on the rise as a result of obesity, hypertension, diabetes, and delayed childbearing. Pregnancy is still contraindicated in women with pulmonary hypertension, severe systemic ventricular dysfunction, dilated aortopathy, and severe left-sided obstructive lesions, but advances in medical and surgical management have resulted in an increasing number of patients with congenital heart defects reaching childbearing age who are interested ...

Effect of a best-practice alert on the rate of influenza vaccination of pregnant women.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:42:46 +0100

CONCLUSION: : Both our rate of vaccination of pregnant women against influenza and the rate of a documented discussion regarding vaccination increased after implementation of the best-practice alert. We recommend that users of electronic medical records add a best-practice alert to improve influenza vaccination rates. LEVEL OF EVIDENCE: : II. PMID: 22270281 [PubMed - in process] (Source: Obstetrics and Gynecology)

Dextranomer-hyaluronic Acid implants misdiagnosed as bladder tumor on transvaginal ultrasonography.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:31:14 +0100

CONCLUSION: : It is important for health care providers to be aware of the radiographic appearance of dextranomer-hyaluronic acid implants in adults and to elicit an appropriate past medical history to avoid misdiagnosis and invasive diagnostic procedures. PMID: 22270444 [PubMed - in process] (Source: Obstetrics and Gynecology)

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Ovarian cancer: current management and future directions

Obstetrics, Gynaecology and Reproductive Medicine — Sat, 21 Jan 2012 03:20:54 +0100

Abstract: Ovarian cancer has the highest mortality of all the gynaecological malignancies. Epithelial ovarian cancer is the most common subtype. Approximately 5–10% occur in women with an inherited predisposition. These patients may benefit from prophylactic surgery. Diagnosis involves measurement of CA 125 and ultrasound. The results of both are combined to give a risk of malignancy index; this is used to decide where treatment takes place. Treatment of advanced epithelial ovarian cancer usually involves debulking surgery and chemotherapy. The correct order of these treatments is currently being evaluated. There are survival benefits if surgery is performed by a specialist gynaecological oncologist. Current standard chemotherapy for epithelial ovarian cancer is carboplatin with paclitax...

Cesarean scar molar pregnancy.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:33:06 +0100

CONCLUSION: : A high index of suspicion is needed for early diagnosis and management of cesarean scar molar pregnancy. PMID: 22270435 [PubMed - in process] (Source: Obstetrics and Gynecology)

Viagra Shrinks Lymphatic Growths in Three Children

MedPage Today OB/GYN — Mon, 30 Jan 2012 03:13:06 +0100

(MedPage Today) -- Sildenafil (Viagra) appears to lessen severe lymphatic malformations in children, according to researchers who have used the drug successfully in three pediatric patients. (Source: MedPage Today OB/GYN)

Cost-benefit analysis of in-hospital influenza vaccination of postpartum women.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:42:35 +0100

CONCLUSION: : Our model suggests that postpartum influenza vaccination is a cost-beneficial approach for prevention of maternal and infantile influenza from a societal perspective. LEVEL OF EVIDENCE: : III. PMID: 22270282 [PubMed - in process] (Source: Obstetrics and Gynecology)

Analysis of the effectiveness of visual inspection with acetic acid/Lugol’s iodine in one-time and annual follow-up screening in rural China

Archives of Gynecology and Obstetrics — Thu, 05 Jan 2012 17:06:19 +0100

Conclusion In a rural, low-resource setting in China, one-time VIA/VILI screening detected more than a half of CIN2 cases, most CIN3 cases and all the cervical cancer cases. Detection rates of CIN2 lesions significantly increased with a 1-year follow-up VIA/VILI screen. Therefore, if multiple cervical cancer screenings are not feasible logistically or financially, a one-time VIA/VILI may be the most efficient strategy to detect cervical cancer and most CIN3 lesions in women in low-resource settings. Content Type Journal ArticleCategory General GynecologyPages 1-6DOI 10.1007/s00404-011-2203-4Authors Rong Li, Department of Gynecological Oncology, Chongqing Cancer Institute/Hospital, 181 Hanyu Lane, Shapingba District, Chongqing, 400030 People’s Republic of ChinaAda...

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Using a multivariate index assay to assess malignancy in a pelvic mass.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:41:11 +0100

Authors: Kim KH, Alvarez RD Abstract A multivariate index assay recently was developed to assist physicians in the assessment of the risk of ovarian cancer in women with pelvic masses undergoing operative intervention. Its aim is to improve the identification of patients with ovarian malignancy so that these patients can be appropriately referred to a subspecialist with ovarian cancer-management expertise, thereby affording the opportunity for improved outcome. This commentary questions the need to obtain a multivariate index assay test in all women with pelvic masses who are scheduled for operative intervention. Common-sense guidelines for more judicious use of this new triage test in the evaluation of these patients also are provided. PMID: 22270289 [PubMed - in process] (Sou...

Pandemic (H1N1) 2009 in pregnant Japanese women in Hokkaido

Journal of Obstetrics and Gynaecology Research — Wed, 28 Sep 2011 04:00:00 +0100

Conclusion: Frequent use of antiviral drugs for prophylaxis and treatment may partially explain the low infection rate and no maternal mortality from pandemic (H1N1) 2009 in Japan. Vaccination reduced infection by 89% in pregnant Japanese women. (Source: Journal of Obstetrics and Gynaecology Research)

Re‐consideration of lymphadenectomy for stage Ib1 cervical cancer

Journal of Obstetrics and Gynaecology Research — Tue, 10 Jan 2012 05:00:00 +0100

Conclusion: The extent of LA can be routinely completed with the removal of Ob, Ii, Ei, Sc and Cd nodes, which may provide a higher quality of life, including the reduction of lymphedema by preventing the removal of the inguinal nodes. (Source: Journal of Obstetrics and Gynaecology Research)

Preimplantation genetic diagnosis for fetal neonatal alloimmune thrombocytopenia due to antihuman platelet antigen maternal antibodies.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:41:49 +0100

CONCLUSION: : In cases in which there is antihuman platelet antigen incompatibility and IVIG cannot be administered, preimplantation genetic diagnosis is a reliable alternative to enable birth of unaffected children. PMID: 22270286 [PubMed - in process] (Source: Obstetrics and Gynecology)

Subjective assessment of ovarian masses using pattern recognition: the impact of experience on diagnostic performance and interobserver variability

Archives of Gynecology and Obstetrics — Fri, 20 Jan 2012 07:05:20 +0100

Conclusions Diagnostic performance of pattern recognition significantly improves with an increasing level of experience, emphasizing the importance of standardized ultrasound training programs with supervision by experts. Content Type Journal ArticleCategory General GynecologyPages 1-7DOI 10.1007/s00404-012-2229-2Authors Florian Faschingbauer, Department of Obstetrics and Gynecology, Erlangen University Hospital, Universitätsstrasse 21–23, 91054 Erlangen, GermanyMichaela Benz, Fraunhofer Institute for Integrated Circuits (IIS), Erlangen, GermanyLothar Häberle, Department of Obstetrics and Gynecology, Erlangen University Hospital, Universitätsstrasse 21–23, 91054 Erlangen, GermanyTamme W. Goecke, Department of Obstetrics and Gynecology, Erlangen University Hosp...

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The quality of sexual life in women with gynaecological cancers

Archives of Gynecology and Obstetrics — Mon, 09 Jan 2012 19:35:21 +0100

Conclusions According to the results obtained from the study, it can be stated that the sexual quality of life of women with gynaecological cancers is moderate and social support, especially support from a significant person, may affect quality of sexual life positively. Content Type Journal ArticleCategory Gynecologic OncologyPages 1-5DOI 10.1007/s00404-011-2210-5Authors Zehra Golbasi, Department of Nursing, Faculty of Health Sciences, Cumhuriyet University, Sivas, TurkeyAyten Senturk Erenel, Department of Nursing, Faculty of Health Sciences, Gazi University, Ankara, Turkey Journal Archives of Gynecology and ObstetricsOnline ISSN 1432-0711Print ISSN 0932-0067 (Source: Archives of Gynecology and Obstetrics)

Agreement between colposcopic impression and histological diagnosis among human papillomavirus type 16‐positive women: a clinical trial using dynamic spectral imaging colposcopy

BJOG: An International Journal of Obstetrics and Gynaecology — Fri, 03 Feb 2012 05:00:00 +0100

Conclusions The sensitivity of DSI colposcopy for CIN2+ is higher in HPV16+ than in non‐16 hrHPV+ women. Furthermore, regardless of HPV16 status, the sensitivity of DSI for CIN2+ is higher than that of the colposcopist, probably because colposcopists tend to miss smaller cervical lesions. (Source: BJOG: An International Journal of Obstetrics and Gynaecology)

New laboratory procedures and rh blood type changes in a pregnant woman.

Obstetrics and Gynecology — Thu, 26 Jan 2012 20:34:56 +0100

CONCLUSION: : Revisions in laboratory procedures for Rh typing may present as a change in the Rh blood type of pregnant women-and as a change in their eligibility for Rh immune globulin. PMID: 22270426 [PubMed - in process] (Source: Obstetrics and Gynecology)

Right endometrioma is related with more extensive obliteration of the Douglas pouch

Archives of Gynecology and Obstetrics — Sat, 24 Dec 2011 16:41:55 +0100

Conclusion Moreover, we also showed that in women with a right endometrioma, incidence of the pouch of Douglas obliteration is higher and the endometriosis tends to be more severe compared to women with a left endometrioma. Our most relevant observation is obliteration of Douglas pouch which was found to be more extensive in women with right ovarian endometrioma. Our results showing left lateral predisposition of endometriomas are in agreement with the previous reports and highlight the retrograde menstruation theory for the pathogenesis of this enigmatic disorder. Content Type Journal ArticleCategory Reproductive MedicinePages 1-4DOI 10.1007/s00404-011-2189-yAuthors Murat Ulukus, Department of Obstetrics and Gynecology, Ege University Faculty of Medicine, Bornova...