MedWorm: Ophthalmology

Birthday Special! IOL Calculation After LASIK

As Seen From Here — Sat, 20 Mar 2010 12:07:00 +0100

Subject: Birthday Special! Video Presentation: IOL Calculation After Excimer Refractive Surgery As Seen From Here turns 5 this month! (Source: As Seen From Here)

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Disparity In Cataract Surgery: Medicare Patients 5.5 Times More Likely To Get Surgery Than VA Patients

Eye Health / Optometry News From Medical News Today — Sat, 20 Mar 2010 07:00:00 +0100

Patients seen at private facilities reimbursed by Medicare were more than 550 percent more likely to have routine cataract surgery than those who received their care from the Department of Veterans Affairs, a strong indication that the frequency of cataract surgery may be responsive to financial incentives to either or both the medical facility and the physicians who perform the procedure... (Source: Eye Health / Optometry News From Medical News Today)

Lack of effect of short-term treatment with Amlodipine and Lisinopril on retinal autoregulation in normotensive patients with type 1 diabetes and mild diabetic retinopathy

Acta Ophthalmologica — Sat, 20 Mar 2010 00:00:00 +0100

Conclusions: Short-term treatment with amlodipine and lisinopril had no significant effect on retinal autoregulation in young normotensive patients with T1D and mild retinopathy, and this lack of effect was similar for the two drugs. A possible normalizing effect of antihypertensive treatment on retinal autoregulation was not observed; however, it might take longer time to improve autoregulation than to reduce the arterial blood pressure. (Source: Acta Ophthalmologica)

Subretinal Implant Restores Unprecedented Level Of Vision To Blind Patients

Eye Health / Optometry News From Medical News Today — Fri, 19 Mar 2010 08:00:00 +0100

Retina Implant, AG, a leading developer of subretinal implants for the visually impaired, today announced scientific revelations discovered during the company's first human clinical trial. The results achieved in the 11 patients that were involved in the trial exceeded the company's expectations for their first trial... (Source: Eye Health / Optometry News From Medical News Today)

Acucela And Otsuka Pharmaceutical Receive FDA Fast Track Designation For ACU-4429 In Patients With Dry AMD

Eye Health / Optometry News From Medical News Today — Fri, 19 Mar 2010 08:00:00 +0100

Acucela Inc., a clinical-stage biotechnology company focused on developing new treatments for blinding eye diseases, and Otsuka Pharmaceutical Co., Ltd., today announced that they have received Fast Track designation from the U.S. Food and Drug Administration (FDA) for ACU-4429, an investigational oral treatment for dry age-related macular degeneration (dry AMD)... (Source: Eye Health / Optometry News From Medical News Today)

[Intraocular hyperintense structure in MRI in a female patient with vertigo.]

Der Ophthalmologe — Fri, 19 Mar 2010 00:00:00 +0100

We present the case of a 77-year-old female patient who complained of dizziness. Consequently, a magnetic resonance imaging (MRI) examination was performed to rule out an intracranial tumor. The examination revealed an intraocular structure with signal hyperintensity in the left eye. The patient was referred to our clinic to screen for an intraocular tumor. Ophthalmological findings together with the medical history unmasked the "tumor" as residual perfluorodecaline vesicles. PMID: 20238222 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe)

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Functional and morphological long-term results after arteriovenous crossing sheathotomy

Acta Ophthalmologica — Fri, 19 Mar 2010 00:00:00 +0100

(Source: Acta Ophthalmologica)

Autologous translocation of the retinal pigment epithelium and choroid in the treatment of neovascular age-related macular degeneration

Acta Ophthalmologica — Fri, 19 Mar 2010 00:00:00 +0100

Conclusion: Functional results of a translocation of RPE and choroid were heterogeneous and rather disappointing in this study. Results may have been influenced negatively by case selection. We found a relatively high rate of adverse events in the postoperative course. In selected cases, e.g. massive submacular haemorrhage or progressive neovascular AMD unresponsive to other treatment options, autologous translocation of RPE and choroid may still be considered. (Source: Acta Ophthalmologica)

Clinical assessment of the optic disc at risk of nonarteritic anterior ischaemic optic neuropathy

Acta Ophthalmologica — Fri, 19 Mar 2010 00:00:00 +0100

(Source: Acta Ophthalmologica)

Retinal attachment after transconjunctival exocryocoagulation of retinal horse shoe tears

Acta Ophthalmologica — Fri, 19 Mar 2010 00:00:00 +0100

(Source: Acta Ophthalmologica)

Impact of iris pigment and pupil size in ultraviolet radiation cataract in rat

Acta Ophthalmologica — Fri, 19 Mar 2010 00:00:00 +0100

Conclusions: Pigmented rats develop less UVR cataract and less ocular inflammation than non-pigmented rats. Pupil size plays a smaller role in UVR cataract development in pigmented rats than in non-pigmented. The role of UVR-induced ocular inflammation in cataract development is still ambiguous. (Source: Acta Ophthalmologica)

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Bilateral macular hole formation secondary to sclopetaria caused by shockwaves transmitted by a posterior vector: case report

BMC Ophthalmology - Latest articles — Fri, 19 Mar 2010 00:00:00 +0100

Conclusion: To our knowledge, this is the first reported case in which trauma posterior to the globes caused bilateral macular hole formation (Source: BMC Ophthalmology - Latest articles)

Increased oxidative DNA damage, lipid peroxidation, and reactive oxygen species in cultured orbital fibroblasts from patients with Graves’ ophthalmopathy: evidence that oxidative stress has a role in this disorder

Eye — Fri, 19 Mar 2010 00:00:00 +0100

Increased oxidative DNA damage, lipid peroxidation, and reactive oxygen species in cultured orbital fibroblasts from patients with Graves’ ophthalmopathy: evidence that oxidative stress has a role in this disorder Eye advance online publication, March 19, 2010. doi:10.1038/eye.2010.31 Authors: C-C Tsai, S-B Wu, C-Y Cheng, S-C Kao, H-C Kau, S-H Chiou, W-M Hsu & Y-H Wei (Source: Eye)

Recurrent endothelial graft rejection after DSAEK triple procedure

Eye — Fri, 19 Mar 2010 00:00:00 +0100

Authors: V Jhanji & R B Vajpayee (Source: Eye)

The effect of preservative-free HP-Guar on dry eye after phacoemulsification: a flow cytometric study

Eye — Fri, 19 Mar 2010 00:00:00 +0100

Authors: M A Sánchez, P Arriola-Villalobos, P Torralbo-Jiménez, N Girón, B de la Heras, R Herrero Vanrell, A Álvarez-Barrientos & J M Benítez-del-Castillo (Source: Eye)

Intravitreal bevacizumab vs intravitreal triamcinolone combined with macular laser grid for diffuse diabetic macular oedema

Eye — Fri, 19 Mar 2010 00:00:00 +0100

Authors: R Forte, G L Cennamo, M Finelli, E Farese, G D'Amico, G Nicoletti, G de Crecchio & G Cennamo (Source: Eye)

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The challenge of uncorrected refractive error: driving the agenda of the Durban Declaration on refractive error and service development

Clinical and Experimental Optometry — Fri, 19 Mar 2010 00:00:00 +0100

The purpose of this article is to highlight the challenge of uncorrected refractive error globally, as well as to discuss recent advocacy successes and innovative programs designed to address the need for broader refractive error service development, particularly in developing countries. The World Health Organization's VISION 2020: The Right to Sight program first posed the challenge to national governments to give priority to strategies and resources targeted towards avoidable causes of blindness and visual impairment, so that these unnecessary forms of blindness or visual impairment can be eliminated globally by the year 2020. The blindness prevention community is challenged to increase in scale its initiatives, which support the attainment of VISION 2020: The Right to Sight goals primar...

Necrologia / Varia

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:230 (DOI:10.1159/000302686) (Source: Ophthalmologica)

Sur la «duplicatio supercilii»

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:231-243 (DOI:10.1159/000302688) (Source: Ophthalmologica)

Statistische Betrachtungen an 426 in der Basler SPACEugenklinik behandelten Fallen von Herpes corneae

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:244-271 (DOI:10.1159/000302689) (Source: Ophthalmologica)

Role of Aqueous Humour Cytopathology in Differential Diagnosis of Iridocyclitis

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:272-282 (DOI:10.1159/000302690) (Source: Ophthalmologica)

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The Head Tilting Test in the Study of Vertical Component Associated with Convergent or Divergent Squint

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:283-294 (DOI:10.1159/000302691) (Source: Ophthalmologica)

Vergleichende Eichversuche mit dem Angiotonometer nach Baurmann und dem Ophthalmodynamometer nach H. K. Müller

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:295-311 (DOI:10.1159/000302692) (Source: Ophthalmologica)

Untersuchungen des Augendruckes nach Verabreichung blutdrucksenkender Mittel

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:312-320 (DOI:10.1159/000302693) (Source: Ophthalmologica)

Sur linsufusance de la capacité du regard

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:321-328 (DOI:10.1159/000302694) (Source: Ophthalmologica)

Correction of Unilateral Aphakia with Contact Lens

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:329-335 (DOI:10.1159/000302695) (Source: Ophthalmologica)

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Contribution à la technique de la trépanation de los au cours de la dacryo-cysto-rhinostomie

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:336-339 (DOI:10.1159/000302696) (Source: Ophthalmologica)

Das polarisationsoptische Verhalten von Hornhaut und Lederhaut unter verschiedenen Bedingungen

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:340-343 (DOI:10.1159/000302697) (Source: Ophthalmologica)

Examen histologique dun greffon de cornée transparent après la kératoplastie

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:344-353 (DOI:10.1159/000302698) (Source: Ophthalmologica)

Buchbesprechungen

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:353-356 (DOI:10.1159/000302699) (Source: Ophthalmologica)

Experimentelle Untersuchungen über den Zusammenhang von Augendrucksteigerung und Gesichtsfeldschädigung

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:357-377 (DOI:10.1159/000302700) (Source: Ophthalmologica)

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Conjunctival Smear Cytology in Xerosis

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:378-386 (DOI:10.1159/000302701) (Source: Ophthalmologica)

Beiträge zu den Augenhintergrundsveränderungen bei Sclerosis multiplex

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:387-396 (DOI:10.1159/000302702) (Source: Ophthalmologica)

Cataracte par rayons X et cystéamine

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:397-402 (DOI:10.1159/000302703) (Source: Ophthalmologica)

Die Behandlung des Glaucoms mit Megaphen

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:403-412 (DOI:10.1159/000302704) (Source: Ophthalmologica)

Posttraumatic Neoformation in the Iris, with Atypical Aspect and Constitution

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:412-416 (DOI:10.1159/000302705) (Source: Ophthalmologica)

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Contents, Vol. 130, 1955

Ophthalmologica — Thu, 18 Mar 2010 23:00:00 +0100

Ophthalmologica 1955;130:I (DOI:10.1159/000302706) (Source: Ophthalmologica)

Mechanisms of macular degeneration.

Vision Research — Thu, 18 Mar 2010 16:12:06 +0100

Authors: Baehr W, Hageman G, Wensel T, Wu S, Zack D PMID: 20230928 [PubMed - in process] (Source: Vision Research)

Health Tip: Recovering From LASIK

MedicineNet Eyesight General — Thu, 18 Mar 2010 07:00:00 +0100

Title: Health Tip: Recovering From LASIKCategory: Health NewsCreated: 3/17/2010 10:10:00 AMLast Editorial Review: 3/18/2010 (Source: MedicineNet Eyesight General)

Intraocular pressure reduction with a fixed treatment protocol in the Early Manifest Glaucoma Trial

Acta Ophthalmologica — Thu, 18 Mar 2010 00:00:00 +0100

Conclusion: With a fixed treatment protocol, the IOP reduction achieved depended very strongly on baseline untreated IOP levels. There seemed to be a lower threshold around 15 mmHg, where therapy did not result in any reduction of IOP. Our results suggest that when effects of IOP-lowering treatment are reported, whether expressed in mmHg or as a percentage of untreated pressure levels, the baseline IOP levels should be specified as well. (Source: Acta Ophthalmologica)

Inspire Announces Results From AZASITE(R) Phase 2 Blepharitis Trials And Plans To Continue Clinical Development In Anterior And Posterior Blepharitis

Eye Health / Optometry News From Medical News Today — Wed, 17 Mar 2010 08:00:00 +0100

Inspire Pharmaceuticals, Inc. (NASDAQ: ISPH) announced the results from two Phase 2 clinical trials with AZASITE (azithromycin ophthalmic solution) 1% for the treatment of blepharitis. Inspire will conduct additional clinical work to continue pursuing a potential indication for treatment of anterior and posterior forms of blepharitis... (Source: Eye Health / Optometry News From Medical News Today)

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Are You Aware March 16, 2010

Are You AWARE Newsfeed — Tue, 16 Mar 2010 23:15:04 +0100

read more (Source: Are You AWARE Newsfeed)

Myopie glaucomateuse

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:316-319 (DOI:10.1159/000300903) (Source: Ophthalmologica)

Optic Coordinates Vertigo

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:320-324 (DOI:10.1159/000300904) (Source: Ophthalmologica)

Angiodiathermy and its Application in Glaucoma

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:325-333 (DOI:10.1159/000300905) (Source: Ophthalmologica)

Zyklanämisation, ein neues Verfahren gegen Glaukom

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:334-348 (DOI:10.1159/000300906) (Source: Ophthalmologica)

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Neuartiges Verfahren für die Plastik des oberen Augenlids

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:349-354 (DOI:10.1159/000300907) (Source: Ophthalmologica)

Goethes Lehre von den «pathologischen Farben»

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:354-364 (DOI:10.1159/000300908) (Source: Ophthalmologica)

The Netherlands Ophthalmological Society 117th Meeting, held on Sunday, 18th September, 1949, in the Wilhelmina-Gasthuis, Amsterdam

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:365-374 (DOI:10.1159/000300909) (Source: Ophthalmologica)

Buchbesprechungen

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:374-380 (DOI:10.1159/000300910) (Source: Ophthalmologica)

Acetylcholin zur Behandlung von Augenverätzungen

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:381-390 (DOI:10.1159/000300911) (Source: Ophthalmologica)

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Diagnostische Hilfsmittel bei der Antihistamintherapie

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:391-399 (DOI:10.1159/000300912) (Source: Ophthalmologica)

Hormone Excretion of Glaucomatous Patients. Comments on the Paper of M. Radnót and M. Csillag

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:400 (DOI:10.1159/000300913) (Source: Ophthalmologica)

Beitrag zur angeborenen Totaltrübung der Hornhaut

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:401-410 (DOI:10.1159/000300914) (Source: Ophthalmologica)

Cas de pseudogliome familial héréditaire dans trois generations (Retinitis exsudativa Coats)

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:411-415 (DOI:10.1159/000300915) (Source: Ophthalmologica)

A Modification of the Suture, Recommended by Kalt a.o.

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:416-417 (DOI:10.1159/000300916) (Source: Ophthalmologica)

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Les penicillium dans les cultures de champignons et de bactéries

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:418-425 (DOI:10.1159/000300917) (Source: Ophthalmologica)

The Oblique Prisma

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:426-427 (DOI:10.1159/000300918) (Source: Ophthalmologica)

Basis and Applications of the Accommodative Unit

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:428-434 (DOI:10.1159/000300919) (Source: Ophthalmologica)

F. C. Donders Last Writings

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:434-436 (DOI:10.1159/000300920) (Source: Ophthalmologica)

Buchbesprechungen

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:437-440 (DOI:10.1159/000300921) (Source: Ophthalmologica)

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Contents, Vol. 120, 1950

Ophthalmologica — Tue, 16 Mar 2010 23:00:00 +0100

Ophthalmologica 1950;120:I (DOI:10.1159/000300922) (Source: Ophthalmologica)

Scoring and Psychometric Properties of the Eye-Drop Satisfaction Questionnaire (EDSQ), An Instrument to Assess Satisfaction and Compliance With Glaucoma Treatment

Medscape Ophthalmology Headlines — Tue, 16 Mar 2010 20:05:50 +0100

A 43-item patient-reported outcome instrument developed to assess patients' satisfaction and compliance with glaucoma treatment shows promise. BMC Ophthalmology (Source: Medscape Ophthalmology Headlines)

Incidence and Management of Acute Endophthalmitis After Intravitreal Bevacizumab (Avastin) Injection

Medscape Ophthalmology Headlines — Tue, 16 Mar 2010 16:54:48 +0100

What's the risk of acute endophthalmitis after intravitreal bevacizumab injection and what can be done to lower the risk? Eye (Source: Medscape Ophthalmology Headlines)

Visually Impaired Students Benefit From New Teaching Tools

Eye Health / Optometry News From Medical News Today — Tue, 16 Mar 2010 11:00:00 +0100

Mastering mathematics can be daunting for many children, but researchers have found that children with visual impairments face disproportionate challenges learning math, and by the time they reach the college level, they are significantly under-represented in science, technology, mathematics and engineering disciplines... (Source: Eye Health / Optometry News From Medical News Today)

Intravitreal bevacizumab alone versus in combination with photodynamic therapy for the treatment of neovascular maculopathy in patients aged 50 years or older: 1-year results of a prospective clinical study

Acta Ophthalmologica — Tue, 16 Mar 2010 00:00:00 +0100

Conclusion: The results of our 12-month prospective study indicate that intravitreal bevacizumab alone has similar efficacy and safety to bevacizumab plus PDT for treatment of patients with neovascular AMD, even treatment-naïve patients. The addition of PDT did not assist in reducing the required total number of bevacizumab injections. (Source: Acta Ophthalmologica)

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Tobacco optic neuropathy (TON) – the historical and present concept of the disease

Acta Ophthalmologica — Tue, 16 Mar 2010 00:00:00 +0100

This article reviews the historical and current concepts of 'tobacco optic neuropathy' (TON) a rare disorder of optic nerve function related to the toxic effects of an unidentified constituent of tobacco. It is considered to be an entity distinct from that often described as 'tobacco-alcohol amblyopia', a disorder better described as a nutritional optic neuropathy. It is suggested that 'tobacco-alcohol amblyopia' is an inappropriate term, because the condition to which it refers is not an amblyopia, and there is little evidence to implicate a toxic effect of either tobacco or alcohol in the pathogenesis of that disorder. (Source: Acta Ophthalmologica)

Acupuncture for treating dry eye: a systematic review

Acta Ophthalmologica — Tue, 16 Mar 2010 00:00:00 +0100

Conclusion: These results provide limited evidence for the effectiveness of acupuncture for treating dry eye. However, the total number of RCTs, the total sample size and the methodological quality were too low to draw firm conclusions. (Source: Acta Ophthalmologica)

Complication Rate Higher With Combined Cataract/glaucoma Surgery

Medscape Ophthalmology Headlines — Mon, 15 Mar 2010 18:56:36 +0100

In patients with cataracts and glaucoma, phacotrabeculectomy to treat both conditions at once produces more surgical complications than phacoemulsification for just the cataracts, researchers say in the March Archives of Ophthalmology. Reuters Health Information (Source: Medscape Ophthalmology Headlines)

The electroretinogram: a useful tool for evaluating age-related macular disease?

Documenta Ophthalmologica — Mon, 15 Mar 2010 17:56:38 +0100

Abstract With an ageing population, the number of age-related macular disease (ARMD) cases will inevitably rise. This gives greater impetus for the need to identify the disease earlier and assess treatments to slow disease progression. Differing electroretinogram (ERG) modalities have been reviewed in relation to the objective assessment of retinal function in ARMD and for monitoring the effectiveness of clinical interventions. Conflicting results have been found with regard to the efficacy of ERG findings in the investigation of ARMD in previous years. The newer multifocal ERG paradigm provides spatial topographical information about retinal function in ARMD. It has shown promising results in monitoring effectiveness of clinical interventions and studies are continuing in...

Feasibility and outcome of automated kinetic perimetry in children

Graefe's Archive for Clinical and Experimental Ophthalmology — Mon, 15 Mar 2010 17:54:58 +0100

Conclusion In 49 out of 50 children (98%) automatic kinetic perimetry was possible in a clinical setting using a commercially available Twinfield perimeter in a session of clinically practical duration. A major advantage is constant test velocity, independent of the examiner. Test performance was not only dependent on age, but also on the child’s maturity and ability to concentrate. Older children tended to detect the stimuli more peripherally. Older children got better results from the examiner evaluation parameters attention and central fixation. Content Type Journal ArticleCategory PediatricsDOI 10.1007/s00417-010-1342-9Authors Stephanie Wilscher, Affiliated Teaching Hospital of the Technical University Kreiskrankenhaus Erding Munich GermanyBettina Wabbels, U...

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Contrast sensitivity after intravitreal antivascular endothelial growth factor therapy for myopic choroidal neovascularization

Graefe's Archive for Clinical and Experimental Ophthalmology — Mon, 15 Mar 2010 17:54:58 +0100

Conclusions Improvements in Pelli-Robson CS scores were observed during the first year after IVR/IVB in eyes with mCNV. Content Type Journal ArticleCategory Retinal DisordersDOI 10.1007/s00417-010-1341-xAuthors Sarah Moussa, The Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery Vienna AustriaSiamak Ansari-Shahrezaei, The Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery Vienna AustriaEva Smretschnig, The Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery Vienna AustriaStefan Hagen, The Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery Vienna AustriaKerstin Steindl-Kuscher, The Ludwig Boltzmann Institute for Retinology and Biomicroscopic Laser Surgery Vienna AustriaIlse Kre...

Refractive lens exchange with distance-dominant diffractive bifocal intraocular lens implantation

Graefe's Archive for Clinical and Experimental Ophthalmology — Mon, 15 Mar 2010 17:54:56 +0100

Conclusions Six-month results of bilateral implantation of a distance-dominant diffractive bifocal IOL for RLE demonstrated efficacy, safety, and predictability in correcting ametropia and presbyopia. Content Type Journal ArticleCategory Refractive SurgeryDOI 10.1007/s00417-010-1345-6Authors José F. Alfonso, Fernández-Vega Ophthalmological Institute Avda. Dres. Fernández-Vega 34 33012 Oviedo SpainLuis Fernández-Vega, Fernández-Vega Ophthalmological Institute Avda. Dres. Fernández-Vega 34 33012 Oviedo SpainSusana Ortí, University of Valencia Optics Department, Faculty of Physics Valencia SpainRobert Montés-Micó, University of Valencia Optics Department, Faculty of Physics Valencia Spain Journal Graefe's Archive for Clinical and Experimental Ophthalmolo...

CET multiple choice answer sheet

Contact Lens and Anterior Eye — Mon, 15 Mar 2010 15:09:27 +0100

(Source: Contact Lens and Anterior Eye)

CET multiple choice questionnaire

Contact Lens and Anterior Eye — Mon, 15 Mar 2010 15:09:27 +0100

(Source: Contact Lens and Anterior Eye)

Evaluation of the effects on conjunctival tissues of Optive eyedrops over one month usage

Contact Lens and Anterior Eye — Mon, 15 Mar 2010 15:09:27 +0100

The objective was to compare the effect on conjunctival tissues of the repeated use, over a one-month period, of Optive compared to Hylocomod eyedrops by a population of dry eye sufferers. The rationale for the study was that among dry eye sufferers who attend eye care practices for symptomatic relief, a large number present with conjunctival anomalies evidenced by tissue staining and that conjunctival recovery is essential to their successful long term management. The hypothesis tested was that the decrease in conjunctival staining with Optive is at least as good, and possibly greater, than that with Hylocomod. The cohort population was made up of 47 subjects (11 male and 26 female) aged 42±16 years with at least mild dry eye symptoms and conjunctival and/or corneal staining. The populat...

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The new role for eye care practitioners in management of dry eye—with and without contact lenses

Contact Lens and Anterior Eye — Mon, 15 Mar 2010 15:09:25 +0100

Twenty-four years ago, BCLA Gold Medal honoree Professor Charles McMonnies, first published a paper on the use of questionnaires to measure and classify patients’ dry eye symptoms . A year later, in 1987, his team deepened that effort by publishing the questions for screening dry eye patients as well . They found that 5% of patients may have been in need of further diagnostic workup for dry eye. If this issue has been researched for so many years, why is the British Contact Lens Association dedicating this special issue to clinical research aspects of dry eye in 2010? The fact remains that the clinical conundrum of determining effective, easy-to-use treatments for dry eye remains an innovating, complex area in clinical research and practice alike and remains worthy of our attention. (Sou...

Editorial Board

Contact Lens and Anterior Eye — Mon, 15 Mar 2010 15:09:25 +0100

(Source: Contact Lens and Anterior Eye)

More Adequate Provision Of Eye Care Services Need To 'Close The Gap' In Vision Loss In Indigenous People, Australia

Eye Health / Optometry News From Medical News Today — Mon, 15 Mar 2010 09:00:00 +0100

Blindness rates in Indigenous Australians are still much higher than in non-Indigenous Australians, despite a probable fall in overall rates of blindness in Indigenous people in the past 30 years, according to research published in the Medical Journal of Australia... (Source: Eye Health / Optometry News From Medical News Today)

Eye Health and Safety Should Be Job One

MedicineNet Eyesight General — Mon, 15 Mar 2010 07:00:00 +0100

Title: Eye Health and Safety Should Be Job OneCategory: Health NewsCreated: 3/13/2010 10:10:00 AMLast Editorial Review: 3/15/2010 (Source: MedicineNet Eyesight General)

Potential anti-angiogenic role of Slit2 in corneal neovascularization.

Experimental Eye Research — Mon, 15 Mar 2010 00:00:00 +0100

Authors: Han X, Zhang MC Slits are large secreted proteins critical for axon guidance and neuronal precursor cell migration in nervous system. Evidence suggests that classical neuronal guidance cues also regulate vascular development. Our objective was to investigate whether neuronal guidance cue Slit2 and Roundabout (Robo) receptors are involved in corneal neovascularization (NV). Corneal NV model in rats was induced by implantation of agarose-coated gelfoam pellets containing basic fibroblast growth factor (bFGF) into corneal stroma. Differential expression of Slit2 and Robo1-4 between normal and neovascularized cornea was detected by real-time RT-PCR and visualized by immunohistochemistry and in situ hybridization. Primary human umbilical vein endothelial cells (HUVECs) were harvest...

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Pigment epithelium-derived factor inhibits erythropoietin- induced retinal endothelial cell angiogenesis by suppression of PI3K/Akt Pathway.

Experimental Eye Research — Mon, 15 Mar 2010 00:00:00 +0100

We report that EPO stimulates EC proliferation, migration, tube formation and permeability whereas PEDF inhibits the EPO-induced ECs proliferation and permeability. Over expression of DN Akt blocked EPO stimulation of proliferation and permeability, while over expression of CA Akt rescues the inhibitory effect of PEDF on proliferation and permeability. These results demonstrate that PEDF may inhibit the EPO-induced proliferation and permeability via PI3K/Akt-dependent pathway. PMID: 20298690 [PubMed - as supplied by publisher] (Source: Experimental Eye Research)

The causes of uveitis in a referral centre of Northern Italy

International Ophthalmology — Sun, 14 Mar 2010 12:26:42 +0100

Abstract Uveitis is a complex intraocular inflammatory disease resulting from several aetiological entities that are linked to geographical, genetic and socioeconomic variables. The purpose of this study was to provide an overview of the distribution patterns of uveitis as seen in a nationwide referral centre at a community hospital in Reggio Emilia, northern Italy, and to compare our data with those reported in previously published international series. The records of 1064 patients of Italian origin with uveitis referred to the Immunology Ocular Unit of the Arcispedale S. Maria Nuova Hospital in Reggio Emilia from 2002 to 2008 were classified and analysed. Data regarding sex, race, residence, age at presentation and at onset of uveitis, ocular involvement, clinical charac...

Exogenous modulation of intrinsic optic nerve neuroprotective activity

Graefe's Archive for Clinical and Experimental Ophthalmology — Sun, 14 Mar 2010 11:30:17 +0100

Conclusions Continuous release of neurotrophic growth factors (NGFs) significantly protects optic nerve function in the experimental model of retinal ischemia observed by PLR analysis. Content Type Journal ArticleCategory Basic ScienceDOI 10.1007/s00417-010-1336-7Authors Sinisa D. Grozdanic, Iowa State University Department of Veterinary Clinical Sciences, College of Veterinary Medicine Ames IA 50011 USATatjana Lazic, Iowa State University Department of Veterinary Clinical Sciences, College of Veterinary Medicine Ames IA 50011 USAMarkus H. Kuehn, University of Iowa Hospitals and Clinics Department of Ophthalmology and Visual Sciences Iowa City IA 52242 USAMatthew M. Harper, Iowa State University Department of Veterinary Clinical Sciences, College of Veterinary Medici...

Thickness of photoreceptor layers in polypoidal choroidal vasculopathy and central serous chorioretinopathy

Graefe's Archive for Clinical and Experimental Ophthalmology — Sun, 14 Mar 2010 11:30:17 +0100

Conclusions Thinning of each photoreceptor layer was observed in the eyes of PCV patients as compared to that observed in the case of normal individuals. The differentiating factors between PCV and CSC, observed using SD-OCT, include the thinning of the OS in eyes with PCV, which makes SD-OCT helpful in differentiating PCV from CSC. More severe photoreceptor alterations were seen in PCV, because fibrin and hemorrhage were present in the subretinal space, which correlated with poorer vision. Content Type Journal ArticleCategory Retinal DisordersDOI 10.1007/s00417-010-1338-5Authors Sotaro Ooto, Kyoto University Graduate School of Medicine Department of Ophthalmology and Visual Sciences 54 Kawahara-cho, Shogoin, Sakyo-ku Kyoto 606-8507 JapanAkitaka Tsujikawa, Kyoto Un...

Attention deficit hyperactivity disorder: diagnosis and treatment masking the ophthalmic clinical presentation of a pineal gland tumour in a teenager

International Ophthalmology — Fri, 12 Mar 2010 06:50:35 +0100

Abstract A 17-year-old male was found to have a fourth cranial nerve palsy and chronic papilloedema following his presentation to our institution with a 6-week history of blurred vision in both eyes and vertical binocular diplopia. A diagnosis of pineal germinoma was made following imaging studies and endoscopic neurosurgical biopsy of the tumour. He was diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) 3 years earlier and treated with amphetamines. Since this diagnosis, he continued to suffer from hyperactive behaviour, poor concentration, worsening headaches and insomnia. Pineal pathology has a known association with sleep disturbance through the disturbance of melatonin synthesis and/or metabolism. This case report serves to highlight how the presence ...

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Variations in the rheostat model of apoptosis: What studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins.

Experimental Eye Research — Fri, 12 Mar 2010 00:00:00 +0100

Authors: Nickells RW Studies of the functions of members of the Bcl2 gene family suggested that apoptosis was controlled by a rheostat in which anti-apoptotic proteins like BCL2 bound and sequestered pro-apoptotic proteins like BAX. Our current understanding of these proteins suggests that this is a simplistic model. The new rheostat model predicts that BH3-only peptides act as neutralizing ligands for the anti-apoptotic proteins, thus allowing molecules like BAX to become activated and initiate mitochondrial dysfunction - a critical step in the intrinsic apoptotic program. Studies of retinal ganglion cell apoptosis indicate that a threshold of BAX expression is required for its successful activation, which is independent of the overall concentration of anti-apoptotic proteins in these...

PI3K/Akt and mTOR/p70S6K Pathways Mediate Neuroprotectin D1-Induced Retinal Pigment Epithelial Cell Survival during Oxidative Stress-Induced Apoptosis.

Experimental Eye Research — Fri, 12 Mar 2010 00:00:00 +0100

Authors: Faghiri Z, Bazan NG The initiation and progression of several forms of retinal degenerations involve excessive, repetitive, and/or sustained oxidative stress that, in turn, mediate photoreceptor cell damage and death. Since phosphatidylinositol 3-kinase (PI3K)/Akt and mTOR/p70S6-kinase pathways are part of survival signaling in cells confronted with oxidative stress, we asked whether or not docosahexaenoic acid-derived neuroprotectin D1 (NPD1) mediates survival upon single-dose and/or repetitive oxidative stress through this pathway. For this purpose, we used human retinal pigment epithelial (ARPE-19) cells challenged by exposure to hydrogen peroxide (H(2)O(2)) plus tumor necrosis factor alpha (TNF-alpha). We found that in single-dose oxidative stress-induced apoptosis, phosph...

Iron, the retina and the lens: A focused review.

Experimental Eye Research — Fri, 12 Mar 2010 00:00:00 +0100

Authors: García-Castiñeiras S This review is focused on iron metabolism in the retina and in the lens and its relation to their respective age-related pathologies, macular degeneration (AMD) and cataract (ARC). Several aspects of iron homeostasis are considered first in the retina and second in the lens, paying particular attention to the transport of iron through the blood-retinal barrier and through the lens epithelial cell barrier, to the immunochemistry of iron-related proteins and their expression in both the retina and the lens, and to the nature of the photochemical damage caused by UV light on both tissues. A comparative overview of some iron related parameters (total iron, transferrin (Tf), transferrin saturation and total iron binding capacity), in plasma and ocular...

A study comparing ocular pressure pulse and ocular fundus pulse in dependence of axial eye length and ocular volume

Acta Ophthalmologica — Fri, 12 Mar 2010 00:00:00 +0100

Conclusion: The present study confirms experimentally that PA, FPA and POBF are dependent on ocular volume and indicates that the pulsatile component of ocular blood flow is not reduced in myopic patients. Accordingly, the relationship between AEL and POBF described previously appears to be a consequence of different ocular volumes. Our findings have important implications for studies using PA or POBF. (Source: Acta Ophthalmologica)

Predictable signs of benign course of polypoidal choroidal vasculopathy: based upon the long-term observation of non-treated eyes

Acta Ophthalmologica — Fri, 12 Mar 2010 00:00:00 +0100

Conclusions: There is certainly a group of PCV eyes with a benign prognosis. Considering the huge cost and risk of current therapies, the initial ocular findings could be deciding factors that determine the necessity for further treatment. (Source: Acta Ophthalmologica)

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Forgotten achievements of Polish retinal research in international ophthalmology

Acta Ophthalmologica — Fri, 12 Mar 2010 00:00:00 +0100

The development of ophthalmology was greatly restricted in Poland in the 19th century, because it was partitioned and occupied by its three dominant neighbours. Polish medical universities were closed, and in Polish hospitals, only clinical work was possible. Those who wanted to study medicine and become ophthalmologists were forced to live and work in exile. Nevertheless, there were some Polish ophthalmologists at that time who had some international influence on retinal research. They contributed to colour vision physiology and pathology, ophthalmoscopy, retinal detachment and gyrate chorioretinal atrophy and congenital choroidal coloboma. The most prominent were Wiktor Szokalski, Ksawery Gałęzowski, Bolesław Wicherkiewicz, Kaziemierz Noiszewski and Michał Bor...

Comparison of higher order aberration profiles between normal and amblyopic eyes in children with idiopathic amblyopia

Acta Ophthalmologica — Fri, 12 Mar 2010 00:00:00 +0100

Conclusion: It seems a strong possibility that a subset of 'idiopathic' amblyopia may be associated with loss of symmetry in wavefront patterns of the two eyes. (Source: Acta Ophthalmologica)

Use of pegaptanib for recurrent and non-clearing vitreous haemorrhage in proliferative diabetic retinopathy

Eye — Fri, 12 Mar 2010 00:00:00 +0100

Authors: D Hornan, N Edmeades, R Krishnan, J Khan & J Lochhead (Source: Eye)

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