MedWorm: Pediatrics

Risk score predicts asthma in preschool children

MedWire News - Pediatrics — Fri, 06 Nov 2009 14:58:22 +0100

A scoring system based on eight clinical parameters predicts future asthma risk in preschool children, say its developers. (Source: MedWire News - Pediatrics)

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Aren’t the lessons in violent or sexual media damaging regardless of how graphic they are?

Thrive, Children's Hospital Boston — Fri, 06 Nov 2009 13:00:57 +0100

Media expert Michael Rich, MD, MPH, director of the Center on Media and Child Health at Children’s Hospital Boston, answers your questions about media use. Last week, he discussed “s. lists” and sex in the media. Here’s this week’s question: Q: My 10 & 12-year-old children want to go to PG-13 and R rated movies with their friends, whose parents think that the sexual innuendo and violence “goes over their heads” because the movies don’t show the graphic details of the sex act or the actual bullet hitting the person. Aren’t the lessons implied and taught damaging to children regardless of the camera angle? -Anxious about Angles in Winnetka, IL A: Dear Anxious, The argument that violence and sex go over kids’ heads is faulty for a few reasons. One is that PG-13...

A Children’s expert answers parents’ questions about the swine flu

Thrive, Children's Hospital Boston — Fri, 06 Nov 2009 12:42:20 +0100

Joanne Cox, MD, director of Children’s Hospital Boston’s Primary Care Center, answers questions about H1N1 during a Karson & Kennedy Morning Show on MIX 104.1. She dispels common myths and answers questions about the swine flu virus and vaccine, like: How do you know if you have regular flu or H1N1? Can you be immune if you’ve already had swine flu? Is there harmful mercury in the vaccine? Related posts:Thimerosal, squalene and Guillain-Barré: Expert answers to your seasonal and H1N1 flu questionsWhy are you getting your child vaccinated? Four parents’ answers.Should my child get the swine flu (H1N1) shot? (Source: Thrive, Children's Hospital Boston)

Inappropriate Clothing Prevents Children Playing Outside

Pediatrics News From Medical News Today — Fri, 06 Nov 2009 11:00:00 +0100

Parents who dress their children in inappropriate clothing could be inadvertently hampering their child's physical activity in childcare settings. The study, reported in BioMed Central's open access journal, International Journal of Behavioral Nutrition and Physical Activity, suggests that inadequate or inappropriate clothing could restrict children's outdoor play. Three-quarters of children aged 3-6 years old in the U.S. (Source: Pediatrics News From Medical News Today)

Campaign Launches To Sound Alarm About The Misuse Of Prescription Drugs Among Teens

Pediatrics News From Medical News Today — Fri, 06 Nov 2009 10:00:00 +0100

The National Council on Patient Information and Education (NCPIE), along with the Substance Abuse and Mental Health Services Administration (SAMHSA) and representatives from 15 nationally recognized prevention, health professional and child advocacy organizations, are launching Maximizing Your Role as a Teen Influencer: What You Can Do to Help Prevent Teen Prescription Drug Abuse. (Source: Pediatrics News From Medical News Today)

Safe Schools/Healthy Students Initiative Can Reduce Violence And Promote Safer Schools

Pediatrics News From Medical News Today — Fri, 06 Nov 2009 09:00:00 +0100

In the wake of several recent highly-publicized stories about violence among school-aged children, a new report shows that school districts participating in the Safe Schools/Healthy Students Initiative substantially improved the safety of their students. (Source: Pediatrics News From Medical News Today)

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Less Brain Injury For Infants Starved Of Oxygen At Birth With Therapeutic Cooling And Accurate MRI Prognosis (TOBY Trial)

Pediatrics News From Medical News Today — Fri, 06 Nov 2009 08:00:00 +0100

An article published Online First and in the January edition of The Lancet Neurology reports that MRI scans on infants who's brains were oxygen deprived can predict with 80 percent accuracy the likelihood of death or disability by eighteen months. Children whose brains are starved of oxygen at birth suffer less brain injury if they undergo therapeutic cooling. The article is the work of Dr Denis Azzopardi, MRC Clinical Sciences Centre, Imperial College London, UK, and colleagues. (Source: Pediatrics News From Medical News Today)

HHS Secretary Calls On States And Communities To Get Health Coverage To Uninsured Children

Pediatrics News From Medical News Today — Fri, 06 Nov 2009 01:00:00 +0100

HHS Secretary Kathleen Sebelius today called on states and communities to join with HHS to redouble efforts to find and enroll the 5 million children who are currently eligible for Medicaid or the Children's Health Insurance Program (CHIP), but are not yet covered. The Secretary issued this call to action as she opened the National Children's Health Insurance Summit in Chicago, kicking off the nation's largest campaign to find and enroll uninsured children in over a decade. (Source: Pediatrics News From Medical News Today)

Continuous subcutaneous insulin infusion vs. multiple daily injections in children with type 1 diabetes: a systematic review and meta-analysis of randomized control trials

NeLM - Paediatrics — Fri, 06 Nov 2009 00:00:00 +0100

Source: DARE Area: Evidence > Drug Specific Reviews CRD Summary: This review concluded that in the short-term (up to 12 months), continuous subcutaneous insulin infusion (insulin pump) provided better control of type 1 diabetes than did multiple daily injections. As the authors stated, the limitations of the evidence, particularly the small numbers of trials and participants included, suggest that this conclusion should be treated with caution. CRD Commentary: The review had clear inclusion criteria. The authors searched a number of relevant sources without language restrictions. The review was restricted to peer-reviewed publications, which could have introduced publication bias. The authors did not attempt to assess the risk of publication bias. Validity was assessed using standard cr...

Bipolar offspring show highest risk during adolescence

MedWire News - Pediatrics — Fri, 06 Nov 2009 00:00:00 +0100

The children of bipolar disorder parents face the highest risk for mood episodes during adolescence, with depression almost always the index episode, the results of a Canadian and Czech study indicate. (Source: MedWire News - Pediatrics)

Antibiotic use linked to asthma in childhood

MedWire News - Pediatrics — Fri, 06 Nov 2009 00:00:00 +0100

Antibiotic use in early life is associated with an increased risk for asthma, rhinoconjunctivitis, and eczema in later childhood, study results suggest. (Source: MedWire News - Pediatrics)

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"Why do paediatricians prescribe antibiotics? Results of an Italian regional project"

BMC Pediatrics - Latest articles — Fri, 06 Nov 2009 00:00:00 +0100

Conclusion: A wide gap between perceived and real determinants of antibiotic prescription exists. This can promote antibiotic overuse. Inadequate parental knowledge can also induce inappropriate prescription. The value of this study is that it simultaneously explored all determinants of antimicrobial prescribing in an entire region involving both professionals and parents. (Source: BMC Pediatrics - Latest articles)

Very Early Bone Marrow Transplant Best for Severe Combined Immunodeficiency

Medscape Pediatrics Headlines — Thu, 05 Nov 2009 16:52:58 +0100

Most infants with severe combined immunodeficiency (SCID) do well with related donor marrow transplants, researchers report. However, those transplanted in the first few months of life tend to have even better survival rates, fewer clinical problems, less need for booster transplants, and better nutritional status. Reuters Health Information (Source: Medscape Pediatrics Headlines)

Steroids a concern in bodybuilding.com supplement recall [News and Features]

AAP News — Thu, 05 Nov 2009 14:50:34 +0100

(Source: AAP News)

'Red Flags Rule' delayed again - until June 2010 [News and Features]

AAP News — Thu, 05 Nov 2009 14:50:33 +0100

(Source: AAP News)

Recall of Centurion premie and meconium packs [News and Features]

AAP News — Thu, 05 Nov 2009 14:50:32 +0100

(Source: AAP News)

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Relationships Among Sleepiness, Sleep Time, and Psychological Functioning in Adolescents

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions Findings highlight the inter-relationships between sleepiness and psychological functioning and the potential importance of addressing sleepiness in health and psychological evaluations of adolescents. (Source: Journal of Pediatric Psychology)

Brief Report: Psychosocial Factors and Pediatric Noncardiac Chest Pain

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions These results suggest NCCP may be part of a broader pattern of somatic responding and sensitivity to physiological arousal. This pattern is associated with both child and maternal functioning. Suggestions for future research are provided. (Source: Journal of Pediatric Psychology)

Brief Report: Adherence to Fluid Recommendations in Children Receiving Treatment for Retentive Encopresis

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions Children's increased clear fluid intake did not equate to high fluid adherence. Children's high juice consumption is concerning as it could place them at risk for other negative health consequences. Future research should examine whether enhanced fluid education and use of behavior change strategies yield higher fluid adherence. (Source: Journal of Pediatric Psychology)

Increasing Parent-Pediatrician Communication about Children's Psychosocial Problems

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions Both the Staff-Scored and Parent-Scored administrations of the PSC improved parent–pediatrician communication on psychosocial issues. The Parent-Scored PSC removed the scoring burden on the medical personnel. (Source: Journal of Pediatric Psychology)

Self-perception and Body Image Associations with Body Mass Index among 8-10-year-old African American Girls

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusion Girls with higher BMI had greater body image discrepancy and were less confident in abilities to be active and eat healthy. Findings may inform the development of obesity interventions for preadolescents. (Source: Journal of Pediatric Psychology)

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The Role of Coping and Temperament in the Adjustment of Children with Cancer

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusion Results partially support the utility of an integrated model including cancer-related stress, coping, and NA in identifying children at risk for internalizing symptoms during treatment. Additional research is needed to inform interventions for this population. (Source: Journal of Pediatric Psychology)

Brief Report: Children's Response to Serious Illness: Perceptions of Benefit and Burden in a Pediatric Cancer Population

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusion The BBSC is internally reliable and preliminary data supports the validity of separate benefit and burden constructs. Children report positive and negative aspects of their illness simultaneously, and perceptions of benefit and burden function as independent constructs. The BBSC is a useful measure for pediatric cancer patients that could be applied to children experiencing other significant life events. (Source: Journal of Pediatric Psychology)

Survivors of Childhood Cancer and Comparison Peers: The Influence of Peer Factors on Later Externalizing Behavior in Emerging Adulthood

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions Mean externalizing behaviors and substance use generally fell within normative ranges for both survivors and peers. Some survivors may benefit from interventions to reduce risk behavior. (Source: Journal of Pediatric Psychology)

A Group Social Skills Intervention Program for Survivors of Childhood Brain Tumors

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions The intervention is feasible and outcomes based on parental reports provide preliminary support for the efficacy of the program. (Source: Journal of Pediatric Psychology)

Family Therapy for Adolescents with Poorly Controlled Diabetes: Initial Test of Clinical Significance

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions BFST produced change in family conflict, a variable shown through previous research to relate to treatment adherence in adolescents with diabetes. The test of clinical significance represents an example of a method useful for pediatric research. (Source: Journal of Pediatric Psychology)

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A Randomized Controlled Trial of Massage Therapy in Children with Sickle Cell Disease

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions These results offer preliminary support for parent-delivered massage therapy as an intervention for SCD pain. (Source: Journal of Pediatric Psychology)

Brief Report: Don't Kiss a Sleeping Dog: The First Assessment of "The Blue Dog" Bite Prevention Program

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:21 +0100

Conclusions Children learned successfully about safe behavior with dogs; thus, the CD can help educate children about dog-bite prevention. (Source: Journal of Pediatric Psychology)

A Mediation Analysis of the ATHENA Intervention for Female Athletes: Prevention of Athletic-Enhancing Substance Use and Unhealthy Weight Loss Behaviors

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:20 +0100

Conclusions ATHENA successfully modified mediators that in turn related to athletic-enhancing substance use and unhealthy weight loss practices. Mediation analyses aid in the understanding of health promotion interventions and inform program development. (Source: Journal of Pediatric Psychology)

Brief Report: Young Children's Risk of Unintentional Injury: A Comparison of Mothers' and Fathers' Supervision Beliefs and Reported Practices

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:20 +0100

Conclusions Maternal supervision has more impact on children's risk of injury than paternal supervision, possibly because mothers spend more time with children than fathers. (Source: Journal of Pediatric Psychology)

Parental HIV/AIDS and Psychosocial Adjustment among Rural Chinese Children

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:20 +0100

Conclusion The findings underscore the urgency and importance of culturally and developmentally appropriate intervention efforts targeting psychosocial problems among children affected by AIDS and call for more exploration of risk and resilience factors, both individual and contextual, affecting the psychosocial wellbeing of these children. (Source: Journal of Pediatric Psychology)

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Cultural Factors and Family-Based HIV Prevention Intervention for Latino Youth

Journal of Pediatric Psychology — Thu, 05 Nov 2009 13:48:20 +0100

Latino youth are the fastest growing ethnic group in the United States and are at considerable risk for HIV and other sexually transmitted infections (STIs), given that they have an earlier onset of sexual activity and use condoms less consistently than European American adolescents. Theorists and scholars have emphasized the importance of taking culture into account in sexuality interventions with Latino adolescents, yet few culturally tailored interventions have been developed for this population. Given the emphasis on familismo and collectivism among Latinos, family-based programs are likely to be well received and could contribute to long-term maintenance of adolescent safety. In this synthesis of the relevant literature, cultural factors that have been identified as relevant to Latino...

Does sleeping late keep you slim?

Thrive, Children's Hospital Boston — Thu, 05 Nov 2009 13:08:18 +0100

Is it possible that children who sleep in on the weekends and holidays are less likely to be overweight than their sleep-deprived counterparts? A recent study suggests as much. But Children’s Hospital Boston sleep specialist Dennis Rosen, MD, says that the study’s findings are problematic. Here, he explains why letting your child sleep in isn’t such a good idea. by Dennis Rosen, MD The connection between insufficient sleep and overweight and obesity is well recognized and has been demonstrated in multiple studies over the last several years. In the November 2009 issue of Pediatrics, researchers report the results of a study conducted in Hong Kong in which they looked at whether differences in sleeping patterns that allowed school-age children to “catch up” on the sl...

H1N1 (swine flu) weekly update: Oct. 28 – Nov. 3

Thrive, Children's Hospital Boston — Thu, 05 Nov 2009 13:00:22 +0100

Here are this week’s H1N1 updates from the HealthMap team of the Children’s Hospital Informatics Program. Afghanistan, Ukraine, Moldova, Croatia, Belarus, Slovenia, Austria, and the Canadian provinces of Newfoundland and Yukon reported their first H1N1 deaths. The World Health Organization (WHO) reported the number of global H1N1 deaths jumped to over 5,700 worldwide. In other statements, WHO reiterated that the vaccines are safe, that one dose is sufficient for adults and children over 10, and that pregnant women should be vaccinated since they are a high-risk group. Researchers at the annual meeting of the Infectious Diseases Society of America reported that influenza vaccination of pregnant women was “85 percent effective in preventing hospitalization in their infants under 6...

Analysis Of Data From Japan Suggests A Protocol For Schools To Decide When Flu Should Trigger A Shutdown

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 13:00:00 +0100

As flu season approaches, parents around the country are starting to face school closures. But how bad should an influenza outbreak be for a school to shut down? A study led by epidemiologists John Brownstein, PhD, and Anne Gatewood Hoen, PhD of the Children's Hospital Boston Informatics Program, in collaboration Asami Sasaki of the University of Niigata Prefecture (Niigata, Japan), tapped a detailed set of Japanese data to help guide decision making by schools and government agencies. (Source: Pediatrics News From Medical News Today)

Teen Girls Diagnosed With STI More Likely To Tell And Seek Treatment For Partners After Watching Video

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 12:00:00 +0100

A study at Johns Hopkins Children's Center found that girls diagnosed with pelvic inflammatory disease (PID) who watched a short educational video were three times more likely to discuss their condition with their partners and to ensure partner treatment than girls diagnosed and treated without seeing the film. (Source: Pediatrics News From Medical News Today)

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Drug Candidate For Treating Spinal Muscular Atrophy Identified By Researchers

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 12:00:00 +0100

A chemical cousin of the common antibiotic tetracycline might be useful in treating spinal muscular atrophy (SMA), a currently incurable disease that is the leading genetic cause of death in infants. This is the finding of a research collaboration involving Adrian Krainer, Ph.D., of Cold Spring Harbor Laboratory (CSHL) and scientists from Paratek Pharmaceuticals and Rosalind Franklin University of Medicine and Science. (Source: Pediatrics News From Medical News Today)

Is Surgery The Best Answer For Children With Sleep Apnea?

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 12:00:00 +0100

For children with obstructive sleep apnea, standard care often includes a tonsillectomy and adenoidectomy. But researchers at Saint Louis University say further research is needed to determine if surgery is the best option for these patients. "We know surgery is associated with improvements in children with sleep apnea, but this research will be the first to allow us to investigate whether or not the surgery causes those improvements," says Ron Mitchell, M.D. (Source: Pediatrics News From Medical News Today)

New Sleep Medicine Research Presented At CHEST 2009

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 12:00:00 +0100

CPAP Therapy Associated With Slight Weight Gain (#7833) Continuous positive airway pressure (CPAP), a common therapy for sleep apnea, is associated with a slight but temporary weight gain in patients. Researchers from the University of Toledo Medical College in Ohio followed 152 patients who underwent CPAP therapy for 1 month. Of the patients, 119 (78 percent) gained an average of 3 lbs. Weight gain occurred in 81 percent of men and 73 percent of women. (Source: Pediatrics News From Medical News Today)

Also In Global Health News: Childhood Vaccines; USAID Administrator; Pakistan Polio Fight; UNICEF Fundraising; Measles In India

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 12:00:00 +0100

The International Examines Contributing Factors To Uneven Distribution Of Childhood Vaccines As a follow-up to the release of the State of the World's Vaccines and Immunization by the WHO, UNICEF and World Bank last month, (Source: Pediatrics News From Medical News Today)

Decision Expected On Enforcement Of Illinois Parental Notification Law

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 11:00:00 +0100

The Illinois Medical Disciplinary Board on Wednesday is expected to decide when to begin enforcement of a state law requiring doctors to notify the parents of minors seeking abortion procedures, the (Source: Pediatrics News From Medical News Today)

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Abortion Not The Only Sticky Issue In Health Care Debate - News Outlets Examine Others

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 10:00:00 +0100

News coverage focuses on some of the sticky issues in health reform, including immigrants' coverage, long term care for the disabled, CHIP and insurance discounts for healthy habits. (Source: Pediatrics News From Medical News Today)

Long-Term Follow-Up Of Children Enrolled In Mexico's Conditional Cash Transfer (CCT) Program 'Oportunidades'

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 08:00:00 +0100

An article published Online First and in a future edition of The Lancet reports that long-term follow-up of children enrolled in Mexico's conditional cash transfer (CCT) program 'Oportunidades' has shown a range of benefits for child health and development. Also, an additional eighteen months of inclusion in the Oportunidades program in very early childhood reduced the number of socio-emotional problems reported in children aged 8 to10 years. (Source: Pediatrics News From Medical News Today)

Long-Term Follow-Up Shows Mexico's Conditional Cash Transfer Programme Confers Health Benefits On Children

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 08:00:00 +0100

Long-term follow-up of children enrolled in Mexico's conditional cash transfer (CCT) programme 'Oportunidades' has shown a range of benefits for child health and development. Furthermore, an additional 18 months of inclusion in the Oportunidades programme in very early childhood reduced the number of socioemotional problems reported in children aged 8-10 years. (Source: Pediatrics News From Medical News Today)

First National Zinc Campaign For Childhood Diarrhea Increases Awareness, But Use Lags Behind

Pediatrics News From Medical News Today — Thu, 05 Nov 2009 08:00:00 +0100

In a study assessing the impact of the first national campaign to scale up zinc treatment of diarrhea in Bangladesh, researchers found that awareness was high but usage lagged behind. In this weeks open access journal PLoS Medicine, Charles Larson and colleagues from International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) report the results of seven repeated ecologic surveys in four areas in Bangladesh, representing 1. (Source: Pediatrics News From Medical News Today)

School Violence Drops With Federal Program

MedicineNet Kids Health General — Thu, 05 Nov 2009 07:00:00 +0100

Title: School Violence Drops With Federal ProgramCategory: Health NewsCreated: 11/5/2009 8:10:00 AMLast Editorial Review: 11/5/2009 (Source: MedicineNet Kids Health General)

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What to Do if You Think You Have H1N1 Swine Flu Virus

MedicineNet Kids Health General — Thu, 05 Nov 2009 07:00:00 +0100

Title: What to Do if You Think You Have H1N1 Swine Flu VirusCategory: Health FactsCreated: 11/5/2009 10:55:00 AMLast Editorial Review: 11/5/2009 10:55:39 AM (Source: MedicineNet Kids Health General)

Help!!!! Out of control 2 year old

Blog from a Pediatrician — Thu, 05 Nov 2009 01:01:50 +0100

Hi, i have a 2 year old son and he is driving me crazy! He sits on, pushes and snatches from his baby sister who is 9 months old. He will not get (Source: Blog from a Pediatrician)

ICS plus LABA best for children with poorly controlled asthma

MedWire News - Pediatrics — Thu, 05 Nov 2009 00:00:00 +0100

Treatment with standard doses of inhaled corticosteroids plus a long acting β2-agonist is more effective for reducing asthma symptoms in children with poorly-controlled disease than simply increasing the ICS dose, research indicates. (Source: MedWire News - Pediatrics)

The burden of influenza in children under 5 years admitted to the Children's Hospital at Westmead in the winter of 2006

Journal of Paediatrics and Child Health — Thu, 05 Nov 2009 00:00:00 +0100

Objective: Active surveillance to determine influenza disease burden in children admitted to hospital with influenza-like illness (ILI).Methods: A prospective hospital-based cohort study conducted June[ndash]October 2006 in children (Source: Journal of Paediatrics and Child Health)

Perceptions of vaccine safety in a global context

Acta Paediatrica — Thu, 05 Nov 2009 00:00:00 +0100

Conclusion: For the implementation of immunization programmes, it is important to develop an in-depth understanding of mechanisms underlying decisions to accept or reject the vaccination of a child. Theoretical models may aid in the understanding of these mechanisms. (Source: Acta Paediatrica)

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Unicare terminating their coverage in illinois

Pediatric Health Associates — Wed, 04 Nov 2009 16:36:00 +0100

ATTENTION UNICARE PATIENTS: Unicare will be leaving the Chicago market by the end of the year. Please contact your employer for information on whom your new health insurance carrier will be. Please note: Although Unicare is recommending employers to switch to HMO of Illinois (Blue Cross Blue Shield HMO), Pediatric Health Associates are not participating providers in that plan. If your employer chooses a different carrier and you are not currently required to choose a PCP, we strongly advise you to check with your employer whether this has changed for you. Please feel free to contact the carrier or our office if you are unsure whether we are participating providers in your new health plan.Unicare will officially end their contracts before January 1, 2010. (Source: Pediatric Health Associate...

Acknowledgment.

Paediatric Drugs — Wed, 04 Nov 2009 16:10:02 +0100

Authors: PMID: 19877721 [PubMed - in process] (Source: Paediatric Drugs)

Juvenile dermatomyositis: advances in pathogenesis, evaluation, and treatment.

Paediatric Drugs — Wed, 04 Nov 2009 16:10:02 +0100

Authors: Huber AM Juvenile dermatomyositis (JDM) is a rare, presumably autoimmune illness that causes proximal muscle weakness and a variety of typical cutaneous features. The study of this illness has been hampered by its rarity but, in recent years, important developments have increased our understanding of JDM. Genetic factors are likely important in the pathogenesis of JDM. These include several Human Leukocyte Antigen alleles, in particular those associated with the 8.1 ancestral haplotype and the tumor necrosis factor-alpha gene 308 polymorphism. Microchimerism, activation of plasmacytoid dendritic cells, and upregulation of type-1 interferon inducible genes also appear to play an important role in the pathogenesis of JDM. The study of JDM has also been limited by a lack of valid...

Vasculitis in children and adolescents: clinical presentation, etiopathogenesis, and treatment.

Paediatric Drugs — Wed, 04 Nov 2009 16:10:02 +0100

Authors: Tullus K, Marks SD The childhood vasculitides are a group of diseases affecting small to large blood vessels. The two most common conditions are Henoch-Schönlein purpura (HSP) and Kawasaki disease (KD). HSP is diagnosed on the basis of typical clinical findings and is mostly a self-limiting disease. KD is the most common vasculitis in infants and the development of coronary artery aneurysms is the major complication. Early treatment with intravenous immunoglobulin and aspirin (acetylsalicylic acid) is required to minimize this risk. All other vasculitides are very rare in children and include anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis, polyarteritis nodosa and Takayasu disease. The etiology of all these vasculitic diseases is generally unknown a...

Treatment strategies to minimize or prevent chronic allograft dysfunction in pediatric renal transplant recipients: an overview.

Paediatric Drugs — Wed, 04 Nov 2009 16:10:02 +0100

Authors: Höcker B, Tönshoff B Long-term allograft survival poses a major problem in pediatric renal transplantation, with allograft nephropathy being the principal cause of graft failure after the first post-transplant year. The mechanisms of nephron loss resulting in graft dysfunction are multiple, comprising both immunologic factors such as acute and chronic antibody- or T-cell-mediated rejection and non-immunologic components. The latter include peri-transplant injuries and renovascular lesions (renal artery stenosis, thrombosis) as well as cardiovascular risk factors such as arterial hypertension and hyperlipidemia. Another relevant issue leading to progressive nephron loss and declining kidney transplant function is acute and chronic nephrotoxicity induced by the calcine...

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Pediatric safety of tizanidine: clinical adverse event database and retrospective chart assessment.

Paediatric Drugs — Wed, 04 Nov 2009 16:10:02 +0100

Authors: Henney HR, Chez M Tizanidine is an imidazoline with central alpha(2)-adrenoceptor agonist activity at both spinal and supraspinal levels, which is indicated as a short-acting drug for the management of spasticity. Despite being used in pediatric populations, there is no adequate information or well controlled studies to document the safety and efficacy of tizanidine in this group. To evaluate the safety of tizanidine in the pediatric population. We compared spontaneous adverse event reports in the Acorda Therapeutics worldwide clinical adverse event database for children (</=16 years; n = 99) and adults (>16 years; n = 1153) who had received tizanidine and for whom at least one adverse event was reported, and performed a retrospective chart review of the safety of tizani...

Topical pimecrolimus: a review of its use in the management of pediatric atopic dermatitis.

Paediatric Drugs — Wed, 04 Nov 2009 16:10:02 +0100

Authors: Yang LP, Curran MP Topical pimecrolimus 1% cream (Elidel(R)) [hereafter referred to as topical pimecrolimus] is a nonsteroidal alternative in the treatment of pediatric atopic dermatitis. In vehicle-controlled, short-term, continuous-use trials in pediatric patients with mild to moderate atopic dermatitis, topical pimecrolimus was effective in treating disease symptoms. Topical pimecrolimus was effective in preventing disease flares and reducing the need for topical corticosteroids in longer term, intermittent-use trials. In addition, topical pimecrolimus was associated with improvements in the health-related quality of life (HR-QOL) of pediatric patients with atopic dermatitis and their parents. In vehicle-controlled trials, topical pimecrolimus was generally as well tolerate...

Best Doctors 2009 Award Winners

DukeHealth.org: Duke Health Features — Wed, 04 Nov 2009 15:09:11 +0100

More than 250 Duke physicians are recognized by fellow doctors throughout North Carolina as among the state’s finest. (Source: DukeHealth.org: Duke Health Features)

An unprecedented partnership with the state’s largest health plans

Thrive, Children's Hospital Boston — Wed, 04 Nov 2009 13:07:34 +0100

As Washington works toward national health reform, we’re pleased to announce that Children’s has established an unprecedented partnership with the state’s largest health plans to help accelerate the transformation of the pediatric care delivery system by expanding innovative approaches and models of care. Working with Blue Cross Blue Shield of Massachusetts, Harvard Pilgrim Health Care and Tufts Health Plan, Children’s and its physicians volunteered to cut its fiscal year 2010 payment rates. A portion of these savings will be targeted to support such efforts as: SCAMPs (Standardized Clinical Assessment and Management Plans) – a revolutionary way to provide clinicians with immediate feedback on the success of their treatments. It uses the best evidence to guide testing and treatm...

Trauma Deadlier for Kids Without Insurance

MedicineNet Kids Health General — Wed, 04 Nov 2009 07:00:00 +0100

Title: Trauma Deadlier for Kids Without InsuranceCategory: Health NewsCreated: 11/3/2009 4:10:00 PMLast Editorial Review: 11/4/2009 (Source: MedicineNet Kids Health General)

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Preemies Raise U.S. Infant Mortality Rate

MedicineNet Kids Health General — Wed, 04 Nov 2009 07:00:00 +0100

Title: Preemies Raise U.S. Infant Mortality RateCategory: Health NewsCreated: 11/4/2009 10:39:00 AMLast Editorial Review: 11/4/2009 10:39:01 AM (Source: MedicineNet Kids Health General)

Dr. Anthony David Hockley

Child's Nervous System — Wed, 04 Nov 2009 06:58:30 +0100

Content Type Journal ArticleCategory ObituaryDOI 10.1007/s00381-009-1010-8Authors Concezio Di Rocco, Rome ItalyPatric M. Schweder, Oxford UKT. Z. Aziz, Oxford UKGuirisk A. Solanki, Birmingham UKHarold L. Rekate, Phoenix USAMarion L. Walker, Salt Lake City USAElizabeth Lewis, East Melbourne AustraliaCarlo Mazza, Verona Italy Journal Child's Nervous SystemOnline ISSN 1433-0350Print ISSN 0256-7040 (Source: Child's Nervous System)

Anesthesia and intraoperative neurophysiological monitoring in children

Child's Nervous System — Wed, 04 Nov 2009 06:58:29 +0100

Conclusion Anesthesia for pediatric patients undergoing surgery where IONM is being performed is consistent with the practice and principles of anesthesia for adults. Although PRIS has not caused major alterations in most patients, concern has modified the practice of some anesthesiologists. Content Type Journal ArticleCategory Focus SessionDOI 10.1007/s00381-009-1023-3Authors Tod Sloan, University of Colorado at Denver and Health Sciences Center Department of Anesthesiology MS 8202, Anschutz Office West (AO1), 12631 E 17th Avenue P.O. Box 6511 Aurora CO 80045 USA Journal Child's Nervous SystemOnline ISSN 1433-0350Print ISSN 0256-7040 (Source: Child's Nervous System)

Laparoscopic retrieval of disconnected shunt catheters from the peritoneal cavity as a day-case procedure in children—early feasibility report

Child's Nervous System — Wed, 04 Nov 2009 06:58:28 +0100

Conclusions Peritoneally migrated shunt catheters have a risk of viscus injury, particularly bowel perforation. In our experience, laparoscopic retrieval of migrated shunt catheters was safe both as an emergency procedure and electively, when it was performed as a day-case basis in selected patients with excellent outcome. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00381-009-1013-5Authors Melissa Short, Birmingham Children’s Hospital Department of Paediatric Surgery Steelhouse Lane Birmingham B4 6NH UKGuirish Solanki, Birmingham Children’s Hospital Department of Neurosurgery Steelhouse Lane Birmingham B4 6NH UKGirish Jawaheer, Birmingham Children’s Hospital Department of Paediatric Surgery Steelhouse Lane Birmingham B4 6NH UK Journal ...

Colesevelam effective in pediatric familial hypercholesterolemia

MedWire News - Pediatrics — Wed, 04 Nov 2009 00:00:00 +0100

Treatment with colesevelam hydrochloride markedly reduces low-density lipoprotein cholesterol levels in children with heterozygous familial hypercholesterolemia, research shows. (Source: MedWire News - Pediatrics)

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Use of hypertonic saline in treatment of bronchiolitis remains unclear

MedWire News - Pediatrics — Wed, 04 Nov 2009 00:00:00 +0100

Hypertonic saline plus epinephrine offers no extra benefit over normal saline plus epinephrine in the treatment of infants with acute bronchiolitis, study findings show. (Source: MedWire News - Pediatrics)

Can procalcitonin measurement help the diagnosis of osteomyelitis and septic arthritis? A prospective trial.

Italian Journal of Pediatrics — Wed, 04 Nov 2009 00:00:00 +0100

Conclusion: PCT is not a good screening test for identifying skeletal infection in children. Larger studies are needed to evaluate still more the place of PCT measurements in the diagnosis of osteomyelitis and septic arthritis. (Source: Italian Journal of Pediatrics)

Sucking characteristics of successfully breastfeeding infants with ankyloglossia: a case series

Acta Paediatrica — Wed, 04 Nov 2009 00:00:00 +0100

(Source: Acta Paediatrica)

A clinical review of 105 patients with PFAPA (a periodic fever syndrome)

Acta Paediatrica — Wed, 04 Nov 2009 00:00:00 +0100

We describe the presentations and clinical outcomes of pediatric patients diagnosed with PFAPA (Periodic Fever, Aphthous lesions, Pharyngitis, and cervical Adenitis).Materials and methods: The medical records of children with recurrent fever and referred between 1998 and 2007 to a tertiary pediatric care hospital were reviewed. Children who met clinical criteria for PFAPA were then asked to participate in a follow-up study.Results: One hundred and five children met study criteria for PFAPA which included at least six episodes of periodic fever. Most (62%) were males, the mean age at onset of PFAPA was 39.6 months (80% were (Source: Acta Paediatrica)

Cardiac troponin-I as a screening tool for myocarditis in children hospitalized for viral infection

Acta Paediatrica — Wed, 04 Nov 2009 00:00:00 +0100

Conclusion: The incidence of myocarditis during viral infections is low and a routine TnI screening for asymptomatic myocarditis is not useful. (Source: Acta Paediatrica)

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The prognostic value of amplitude integrated EEG in neonatal sepsis and/or meningitis

Acta Paediatrica — Wed, 04 Nov 2009 00:00:00 +0100

Conclusion: Low voltage background pattern, SWC and EA on aEEG are helpful to predict neurological outcome in infants with neonatal sepsis or meningitis. (Source: Acta Paediatrica)

Tick-borne encephalitis presenting as fever without localising signs—a case series

European Journal of Pediatrics — Tue, 03 Nov 2009 21:15:54 +0100

Conclusion TBE infection has to be considered in the differential diagnosis of FWLS in endemic areas. Foremost, FWLS characterised by a biphasic fever course and accompanied by headache in patients in a reduced general condition. Affirming that in patients presenting as FWLS also cases of TBE are contained, this disease is underreported. Content Type Journal ArticleCategory Short ReportDOI 10.1007/s00431-009-1097-7Authors Patrick Michael Meyer, Triemli Hospital Zurich Department of Paediatrics Birmensdorferstrasse 497 8063 Zurich SwitzerlandHanspeter Zimmermann, Swiss Federal Office of Public Health Division of Communicable Diseases 3003 Bern SwitzerlandPhilippe Goetschel, Triemli Hospital Zurich Department of Paediatrics Birmensdorferstrasse 497 8063 Zurich Switzerla...

An experimental heart valve saves a child with H1N1

Thrive, Children's Hospital Boston — Tue, 03 Nov 2009 16:26:11 +0100

The Wall Street Journal features a story about a Children’s Hospital Boston patient with congenital heart disease who was stricken with H1N1 and required a new heart valve. Because the boy was too sick to undergo open-heart surgery, James Lock, MD, led a team that implanted the new valve using a catheter. Lock and Peter Laussen, MD, chief of cardiovascular critical care at Children’s, talk about how H1N1 presents a serious problem for children with heart disease. Last week, a multicenter study led by Children’s reported good preliminary results in 30 patients receiving this catheter-implanted valve, which is threaded up a leg vein to the heart. Related posts:One patient’s story: in utero heart surgery saves a babyOne mother’s story: our baby’s congenit...

Is autism really on the rise?

Thrive, Children's Hospital Boston — Tue, 03 Nov 2009 14:21:25 +0100

Photo by Webb Chappell By Ellen Hanson, PhD, Developmental Medicine Center “Has autism increased or hasn’t it?” As a researcher and psychologist with a specialty in developmental disabilities and autism spectrum disorders (ASDs), this is a question I get all the time. I wish I had a short answer, but I don’t. On the other hand, if you have a few minutes, read on. The question is a really important one. A study just came out in Pediatrics, saying that the prevalence of ASDs is now one in 91 U.S. children – and one in 58 boys. This is much higher than the most recently quoted rate of one in 150. And that is up from one in 1500 in the early 1990s. That jump would scare anyone! But is it real? This should be a “yes” or “no” question, right? But the first thing to remember is...

CDC Study Links 2 Antibiotics to Birth Defects

MedicineNet Kids Health General — Tue, 03 Nov 2009 07:00:00 +0100

Title: CDC Study Links 2 Antibiotics to Birth DefectsCategory: Health NewsCreated: 11/2/2009 6:10:00 PMLast Editorial Review: 11/3/2009 (Source: MedicineNet Kids Health General)

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Food Stamps Help Stave Off Hunger in Many U.S. Homes

MedicineNet Kids Health General — Tue, 03 Nov 2009 07:00:00 +0100

Title: Food Stamps Help Stave Off Hunger in Many U.S. HomesCategory: Health NewsCreated: 11/2/2009 4:10:00 PMLast Editorial Review: 11/3/2009 (Source: MedicineNet Kids Health General)

TV Linked to More Child Aggression

MedicineNet Kids Health General — Tue, 03 Nov 2009 07:00:00 +0100

Title: TV Linked to More Child AggressionCategory: Health NewsCreated: 11/3/2009 10:31:00 AMLast Editorial Review: 11/3/2009 10:31:07 AM (Source: MedicineNet Kids Health General)

Birthweight and breastfeeding influence childhood asthma risk

MedWire News - Pediatrics — Tue, 03 Nov 2009 00:00:00 +0100

Low birthweight is associated with an increased risk for childhood asthma that is not modified by breastfeeding, results of a US study show. (Source: MedWire News - Pediatrics)

Air filtration/ventilation device reduces pediatric asthma symptoms

MedWire News - Pediatrics — Tue, 03 Nov 2009 00:00:00 +0100

Air cleaning combined with improved ventilation can reduce the symptoms of asthma in children with the condition, study findings published in the journal Building and Environment show. (Source: MedWire News - Pediatrics)

Health related quality of life of Dutch children: psychometric properties of the PedsQL in the Netherlands

BMC Pediatrics - Latest articles — Tue, 03 Nov 2009 00:00:00 +0100

Conclusions: The Dutch version of the PedsQL has adequate psychometric properties and can be used as a health related quality of life instrument in paediatric research in the Netherlands. (Source: BMC Pediatrics - Latest articles)

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Research Notes

Child and Adolescent Psychopharmacology News — Tue, 03 Nov 2009 00:00:00 +0100

Child and Adolescent Psychopharmacology News 14(2): 13-14 (Source: Child and Adolescent Psychopharmacology News)

Post-Test and Evaluation for Child & Adolescent Psychopharmacology News 14(2)

Child and Adolescent Psychopharmacology News — Tue, 03 Nov 2009 00:00:00 +0100

Child and Adolescent Psychopharmacology News 14(2): 12-12 (Source: Child and Adolescent Psychopharmacology News)

Autism and Sleep: Basics for the Clinician

Child and Adolescent Psychopharmacology News — Tue, 03 Nov 2009 00:00:00 +0100

Child and Adolescent Psychopharmacology News 14(2): 9-11 (Source: Child and Adolescent Psychopharmacology News)

Long-term effects of rapid weight gain in children, adolescents and young adults with appropriate birth weight for gestational age: the kiel obesity prevention study

Acta Paediatrica — Tue, 03 Nov 2009 00:00:00 +0100

Conclusion: Rapid weight gain was related to increases in height, weight, a higher prevalence of overweight and central fat distribution. In addition, rapid weight gain was related to a higher REE in boys, but not to cardio-metabolic risk factors. (Source: Acta Paediatrica)

Bronchiolitis and Respiratory Syncytial Virus [Advice for Patients]