MedWorm: Pediatrics

Circadian rhythm genes linked to pediatric bipolar disorder

MedWire News - Pediatrics — Fri, 20 Nov 2009 15:00:03 +0100

Polymorphisms in two genes related to the circadian rhythm may be associated with the development of pediatric bipolar disorder, although not with age at onset, US researchers have discovered. (Source: MedWire News - Pediatrics)

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My family’s story: surviving swine flu

Thrive, Children's Hospital Boston — Fri, 20 Nov 2009 13:38:11 +0100

Thanks to H1N1, Halloween came on November 15 for the Lord and Ladies of the Cyr household My wife, Sara, and I are the proud parents of newly minted 4-year-old triplets, and this fall we just haven’t been able to get healthy in our house. We get over one illness and another one crops up a week later. Fevers come and go. Coughs are incessant. Headaches bloom and recede. It’s been never-ending. So none of us was feeling particularly well on the Thursday before Halloween when Sara called me at work and told me she had spiked a fever. We weren’t sure it was H1N1, but working in the Public Affairs Department here at Children’s Hospital Boston, I spend much of my time communicating about swine flu, so I know fever is one of the bellwether symptoms. Alarm bells started going off in...

My 9 year old is imitating Michael Jackson’s dance moves, how can I talk to him about it?

Thrive, Children's Hospital Boston — Fri, 20 Nov 2009 13:00:43 +0100

Media expert Michael Rich, MD, MPH, director of the Center on Media and Child Health at Children’s Hospital Boston, answers your questions about media use. Last week, he discussed telenovelas and toddlers. Here’s this week’s question: Q: I have two kids, ages 6 and 9, and they are both big Michael Jackson fans. I don’t think the music is a problem, though some of the lyrics are, so I don’t let them listen to just any old song. But my question is about the dance moves in videos. The kids know they can get MJ on YouTube (my son simply presses the letter M, and Michael Jackson is the first suggestion), but I always insist on watching with them. My nine year old has recently started imitating the dance moves (crotch grabbing and all!). I am concerned that he doesn’t fully understan...

Optimizing neurodevelopmental outcomes in infants and children following prenatal SSRI exposure

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:58:02 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 511-514. (Source: Future Medicine: Pediatric Health)

Acute seizure management in children

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:38:16 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 543-549. (Source: Future Medicine: Pediatric Health)

Bulletin Board

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:38:14 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 521-523. (Source: Future Medicine: Pediatric Health)

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Adolescent attitudes towards tanning: does age matter?

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:38:11 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 565-578. (Source: Future Medicine: Pediatric Health)

Reducing global mortality from childhood diarrhea: future directions

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:38:05 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 515-519. (Source: Future Medicine: Pediatric Health)

Emergency treatment options for pediatric traumatic brain injury

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:38:00 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 533-541. (Source: Future Medicine: Pediatric Health)

Gemcitabine and vinorelbine therapy for patients with Hodgkin lymphoma

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:37:45 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 525-532. (Source: Future Medicine: Pediatric Health)

Suicidal events in adolescents: how clear are the warning signs?

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:37:35 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 551-563. (Source: Future Medicine: Pediatric Health)

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Pediatric Hodgkin lymphoma: past, present and future

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:37:24 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 593-606. (Source: Future Medicine: Pediatric Health)

Complications of infection in pediatric spine surgery

Future Medicine: Pediatric Health — Fri, 20 Nov 2009 12:37:17 +0100

Pediatric Health , December 2009, Vol. 3, No. 6, Pages 579-592. (Source: Future Medicine: Pediatric Health)

Tuberculosis

Acta Paediatrica — Fri, 20 Nov 2009 00:00:00 +0100

(Source: Acta Paediatrica)

How childhood stress can lead to adult depression

Thrive, Children's Hospital Boston — Thu, 19 Nov 2009 20:29:14 +0100

Childhood should be a happy time, not a stressful time—that’s something everyone can agree on. But for many children, childhood is very stressful. Family tragedy, natural disasters, poverty, abuse or exposure to violence (in the home, in the community, or when the country is at war) are just a few examples of what can turn childhood from a dream into a nightmare. This is terrible for children. It’s not just a matter of robbing them of happiness; more and more research is showing that stress early in life can actually change the way a child’s brain works—for life. A study in the journal Nature Neuroscience this month helps us understand why. Researchers stressed baby mice (by separating them from their mothers daily for the first 10 days of life). The mice that had this early life...

Social Skills Improved for Alcohol-Damaged Kids (CME/CE)

MedPage Today Pediatrics — Thu, 19 Nov 2009 20:00:00 +0100

Teaching children social skills can overcome some of the damage caused by prenatal alcohol exposure, researchers said. (Source: MedPage Today Pediatrics)

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Contaminants found in some Genzyme products [News and Features]

AAP News — Thu, 19 Nov 2009 19:56:58 +0100

(Source: AAP News)

More influenza vaccine FDA-approved for use in children [News and Features]

AAP News — Thu, 19 Nov 2009 19:56:57 +0100

(Source: AAP News)

Baby's Sleep Position Is The Major Factor In 'Flat-Headedness'

Pediatrics News From Medical News Today — Thu, 19 Nov 2009 18:00:00 +0100

A baby's sleep position is the best predictor of a misshapen skull condition known as deformational plagiocephaly - or the development of flat spots on an infant's head - according to findings reported by Arizona State University scientists in the December issue of the journal Pediatrics. (Source: Pediatrics News From Medical News Today)

H1N1 (swine flu) weekly update: Nov. 11 – 17

Thrive, Children's Hospital Boston — Thu, 19 Nov 2009 13:00:02 +0100

Here are this week’s H1N1 updates from the HealthMap team of the Children’s Hospital Informatics Program. Burundi and Greenland have reported their 1st cases of H1N1, while North Cyprus, Bosnia, Poland, Kosovo, Tunisia, and Morocco have reported their 1st H1N1 deaths. The World Health Organization (WHO) recommended early administration of antiviral medicines to prevent death in pregnant women, very young children, and people with underlying medical problems who fall ill with H1N1. Additionally, the WHO has warned of the dangers of H1N1 spreading rapidly at any big sporting or cultural events, as Saudi Arabia prepares for the arrival of 2.5 million pilgrims for the Hajj (November 25–29). Nine cases have already been diagnosed among the 500,000 early arrivals. Amidst recommendations t...

Health Overhaul Triggers Debate About What Lies Ahead For The Children's Health Program

Pediatrics News From Medical News Today — Thu, 19 Nov 2009 11:00:00 +0100

Kaiser Health News staff writer Mary Agnes Carey reports on the future of the Children's Health Insurance Program. One of its staunchest backers, Sen. Jay Rockefeller, "isn't ready to see it swallowed up by a new health insurance marketplace designed by Congress" (11/17). This information was reprinted from (Source: Pediatrics News From Medical News Today)

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Ending The 'Endless Adolescence': U.Va. Psychologists Tell How In New Book

Pediatrics News From Medical News Today — Thu, 19 Nov 2009 09:00:00 +0100

Parental nurturing is backfiring, and as a result a generation of teens is growing up less independent, less skilled at common tasks - from doing laundry to choosing college classes - and increasingly unprepared for adulthood, studies show. Even young adults often are highly reliant on their parents; more than 60 percent of 23-year-olds and 30 percent of 25-year olds are still financially supported by their parents. (Source: Pediatrics News From Medical News Today)

Prediction Of Shortage Of Intensive Care Beds For Children With Swine Flu (UK)

Pediatrics News From Medical News Today — Thu, 19 Nov 2009 08:00:00 +0100

Research published ahead of print in the Archives of Disease in Childhood reports that if UK swine flu resurges during the winter months, there may not be a sufficient amount of intensive care beds for one of the most seriously affected groups: children. More than half of admissions to pediatric intensive care units (PICUs) are unplanned. Respiratory illness is the second largest cause of admission. (Source: Pediatrics News From Medical News Today)

Are Teenagers Wired Differently Than Adults?

Pediatrics News From Medical News Today — Thu, 19 Nov 2009 08:00:00 +0100

Parents have long suspected that the brains of their teenagers function differently than those of adults. With the advent of magnetic resonance imaging, or MRI, we have begun to appreciate how the brain continues to develop structurally through adolescence and on into adulthood. High emotionality is a characteristic of adolescents and researchers are trying to understand how 'emotional areas' of the brain differ between adults and adolescents. (Source: Pediatrics News From Medical News Today)

Health Tip: When Infants Get Diarrhea

MedicineNet Kids Health General — Thu, 19 Nov 2009 07:00:00 +0100

Title: Health Tip: When Infants Get DiarrheaCategory: Health NewsCreated: 11/19/2009 8:10:00 AMLast Editorial Review: 11/19/2009 (Source: MedicineNet Kids Health General)

Toddlers, Obese Kids Suffer Most From Smoke

MedicineNet Kids Health General — Thu, 19 Nov 2009 07:00:00 +0100

Title: Toddlers, Obese Kids Suffer Most From SmokeCategory: Health NewsCreated: 11/18/2009 4:10:00 PMLast Editorial Review: 11/19/2009 (Source: MedicineNet Kids Health General)

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Late Preterm Births Increasing in U.S.

MedicineNet Kids Health General — Thu, 19 Nov 2009 07:00:00 +0100

Title: Late Preterm Births Increasing in U.S.Category: Health NewsCreated: 11/18/2009 12:10:00 PMLast Editorial Review: 11/19/2009 (Source: MedicineNet Kids Health General)

Wall Street community invests in future of groundbreaking research and lifesaving care for children battling cancer at St. Jude

St. Jude Children's Research Hospital — Thu, 19 Nov 2009 00:00:00 +0100

Wall Street celebrates 20 years of caring for St. Jude kids (Source: St. Jude Children's Research Hospital)

Body fluids and salt metabolism - Part I

Italian Journal of Pediatrics — Thu, 19 Nov 2009 00:00:00 +0100

There is a high frequency of diarrhea and vomiting in childhood. As a consequence the focus of the present review is to recognize the different body fluid compartments, to clinically assess the degree of dehydration, to know how the equilibrium between extracellular fluid and intracellular fluid is maintained, to calculate the effective blood osmolality and discuss both parenteral fluid requirments and repair. (Source: Italian Journal of Pediatrics)

Recurrent asthma attacks may accelerate airway remodeling

MedWire News - Pediatrics — Thu, 19 Nov 2009 00:00:00 +0100

Recurrent asthma attacks may aggravate airway remodeling, say Japanese researchers who found that acute attacks are associated with hypersecretion of epidermal growth factor and amphiregulin in the airways. (Source: MedWire News - Pediatrics)

Mouse Study Points to Possible Down Syndrome Treatment (CME/CE)

MedPage Today Pediatrics — Wed, 18 Nov 2009 20:27:11 +0100

Drugs that stimulate norepinephrine signaling might allow for normal cognitive development in children with Down syndrome, said researchers who tested the hypothesis in mice. (Source: MedPage Today Pediatrics)

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Massachusetts takes action on school bullying

Thrive, Children's Hospital Boston — Wed, 18 Nov 2009 18:50:06 +0100

Kids who have fell victim to taunts and ridicule in school may finally be awarded a victory this week as Massachusetts lawmakers hold hearings on nearly a dozen bills that aim to crack down on school bullying. Bullying, as defined by the American Psychological Association, is an aggressive behavior that’s intended to cause distress or harm, and involves an imbalance of power or strength between the aggressor and the victim.For every child who is or has been bullied, it’s stressful and distracting at best, and frightening, damaging to self-esteem and physically dangerous at worst. If you know a child that is being bullied, offer them these tips: Act brave. Hold your head up and walk by as if you are not afraid of the bully. Bullies often pick on kids they think are weak be...

Do Pacifiers Interfere With Breastfeeding Success?

Medscape Pediatrics Headlines — Wed, 18 Nov 2009 15:54:18 +0100

This study provides practical help for pediatric providers who are faced with the "pacifier question." Medscape Pediatrics (Source: Medscape Pediatrics Headlines)

Bottled Water a Risk Factor for Early Childhood Caries

Medscape Pediatrics Headlines — Wed, 18 Nov 2009 15:19:49 +0100

Young children who drink significant amounts of bottled water, which lacks fluoride because of the purification process, are at high risk for early childhood caries. Medscape Medical News (Source: Medscape Pediatrics Headlines)

Meet the Dean: Nancy C. Andrews, MD, PhD

DukeHealth.org: Duke Health Features — Wed, 18 Nov 2009 15:11:54 +0100

Meet the new dean of Duke University School of Medicine and learn about her vision and direction for the program. (Source: DukeHealth.org: Duke Health Features)

Sports violence: girls behaving badly?

Thrive, Children's Hospital Boston — Wed, 18 Nov 2009 13:40:43 +0100

New Mexico Lobos soccer player Elizabeth Lambert's actions led to her suspension. The media’s attention has been captured by recent incidents of violence in girls’ and women’s sports, including a bench clearing brawl during a high school soccer game in Providence, and the suspension of New Mexico Lobos soccer player Elizabeth Lambert for unsportsmanlike conduct. David Mooney, MD, MPH, director of the Trauma Program at Children’s Hospital Boston and girls soccer coach, addresses issues raised by this recent media coverage. Passion for the game is one of the central tenets of sports. Without passion, you might as well just watch the highlight tape. Soccer is one of many physical contact sports. Having played organized soccer for more than 30 years and...

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Robot-Assisted Surgery Unproven in Children (CME/CE)

MedPage Today Pediatrics — Wed, 18 Nov 2009 12:59:13 +0100

Robot-assisted surgery is safe for a number of procedures performed on children, but little evidence exists that it works better than conventional techniques, a new study found. (Source: MedPage Today Pediatrics)

Health, Policy Experts Gather For 3-Day Conference On Family Planning

Pediatrics News From Medical News Today — Wed, 18 Nov 2009 12:00:00 +0100

By offering family planning services to people seeking HIV/AIDS information and treatment, Africa's population growth rate could be curbed by 2.5 percent, health experts said Monday during an international family health conference in Kampala, Uganda, Agence France-Presse reports (11/16). (Source: Pediatrics News From Medical News Today)

STI Rates Increase Among Mississippi Teens

Pediatrics News From Medical News Today — Wed, 18 Nov 2009 12:00:00 +0100

Teenagers ages 15 through 19 now comprise nearly 40% of Mississippi's sexually transmitted infection cases, the Jackson Clarion-Ledger reports. The number of chlamydia cases among teens increased 25% over the last five years, and numbers of cases in 2008 were close to the 2007 total. (Source: Pediatrics News From Medical News Today)

States Take Action To Reduce Risk Factors For Preterm Birth

Pediatrics News From Medical News Today — Wed, 18 Nov 2009 12:00:00 +0100

For the second consecutive year, the United States earned only a "D" on the March of Dimes Premature Birth Report Card, demonstrating that more than half a million of our nation's newborns didn't get the healthy start they deserved. In the 2009 Premature Birth Report card, seven states improved their performance by one letter grade and two fared worse. (Source: Pediatrics News From Medical News Today)

Studies Suggest Parental Monitoring Can Help Decrease Adolescent Marijuana Use

Pediatrics News From Medical News Today — Wed, 18 Nov 2009 10:00:00 +0100

Marijuana is the most widely used illicit drug by adolescents, with almost 42% of high school seniors admitting to having experimented with it. Continued marijuana use may result in a number of serious consequences including depression, cognitive impairment, cardiovascular disease, and certain forms of cancer. As such, it is critical to prevent marijuana use by adolescents and numerous behavioral and medical scientists have been trying to establish the best means of prevention. (Source: Pediatrics News From Medical News Today)

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New presenting symptoms of Chiari I malformation: report of two cases

Child's Nervous System — Wed, 18 Nov 2009 09:23:29 +0100

Conclusions These case reports can suggest the association of hemihypertrophy and claw hand with Chiari I malformation and syringomyelia. Further studies are necessary to assess the real incidence of focal motor deficits and mesodermic disorders in Chiari I malformation in order to clarify their pathogenetical mechanisms. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00381-009-1043-zAuthors Benedetta Ludovica Pettorini, Birmingham Children’s Hospital Paediatric Neurosurgery Birmingham UKChenur Oesman, Birmingham Children’s Hospital Paediatric Neurosurgery Birmingham UKShailendra Magdum, Birmingham Children’s Hospital Paediatric Neurosurgery Birmingham UK Journal Child's Nervous SystemOnline ISSN 1433-0350Print ISSN 0256-7040 (Source: Child'...

Viagra Helpful for Children With Heart Defect

MedicineNet Kids Health General — Wed, 18 Nov 2009 07:00:00 +0100

Title: Viagra Helpful for Children With Heart DefectCategory: Health NewsCreated: 11/17/2009 4:10:00 PMLast Editorial Review: 11/18/2009 (Source: MedicineNet Kids Health General)

Folic Acid, B12 May Increase Cancer Risk

MedicineNet Kids Health General — Wed, 18 Nov 2009 07:00:00 +0100

Title: Folic Acid, B12 May Increase Cancer RiskCategory: Health NewsCreated: 11/18/2009 9:39:00 AMLast Editorial Review: 11/18/2009 9:39:21 AM (Source: MedicineNet Kids Health General)

Tween: Child Development

MedicineNet Kids Health General — Wed, 18 Nov 2009 07:00:00 +0100

Title: Tween: Child DevelopmentCategory: Health and LivingCreated: 11/18/2009 10:41:00 AMLast Editorial Review: 11/18/2009 10:41:12 AM (Source: MedicineNet Kids Health General)

Most common allergic march sequences identified

MedWire News - Pediatrics — Wed, 18 Nov 2009 00:00:00 +0100

There are numerous variants of the “allergic march,” with eczema followed by asthma and then rhinitis being the most common sequence, say UK researchers. (Source: MedWire News - Pediatrics)

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Correlation between 6-min walk test and exercise stress test in healthy children

Acta Paediatrica — Wed, 18 Nov 2009 00:00:00 +0100

Conclusions: SMWT distance is significantly correlated with the eVO2 obtained during the EST. This indicates that SMWT is also one of the predictive markers for EST performance. (Source: Acta Paediatrica)

Cytokine levels in neonatal necrotizing enterocolitis and long-term growth and neurodevelopment

Acta Paediatrica — Wed, 18 Nov 2009 00:00:00 +0100

Conclusion: This study suggests that increased serum levels of pro-inflammatory cytokines may play a role in the poor growth and neurodevelopment associated with this high-risk population. (Source: Acta Paediatrica)

High-dose Folic Acid and B12 May Hike Cancer Risk (CME/CE)

MedPage Today Pediatrics — Tue, 17 Nov 2009 20:00:00 +0100

High-dose folic acid and vitamin B12 supplements were associated with an increased incidence of cancer (MedPage Today) -- particularly lung cancer -- in a post-hoc analysis of two Norwegian trials. (Source: MedPage Today Pediatrics)

Uninsured trauma victims more likely to die of their injuries

Thrive, Children's Hospital Boston — Tue, 17 Nov 2009 18:37:59 +0100

Research from Children’s Hospital Boston’s Heather Rosen, MD, MPH, finds that people who are admitted to the hospital for trauma are more likely to die from their injuries if they don’t have health insurance than if they do. In this WBUR report, Rosen offers some possible explanations for the alarming disparity. Her research was also reported on by the Associated Press. Related posts:Health headlines: Premature babies, burn injuries and cherry flavored TamifluGlass-table injuries to children prompts industry changesConcussion injuries in youth athletes (Source: Thrive, Children's Hospital Boston)

A New Normal for Cancer Survivors

DukeHealth.org: Duke Health Features — Tue, 17 Nov 2009 15:05:50 +0100

Learn how Duke is changing care to meet the needs of an exploding patient population -- cancer survivors (Source: DukeHealth.org: Duke Health Features)

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More and more teens infected with STDs

Thrive, Children's Hospital Boston — Tue, 17 Nov 2009 14:11:31 +0100

The CDC just released its annual report on sexually transmitted diseases and the results for teens are pretty disturbing. Although 15- to 24-year-olds represent only 25% of the sexually experienced population, they acquire nearly half of all new STDs. The report notes that sexually active teens are at a higher risk of contracting an STD because of a combination of behavioral, biological and cultural reasons. Barriers to accessing quality STD prevention services– like lack of insurance and transportation, or concerns about confidentiality, may also play a big role, the study concludes. It’s well known that alcohol and drug use can contribute to adolescents making dangerous choices when it comes to sexual activity. But even so, pediatricians don’t routinely screen patients...

Boys, Twins And Firstborn Babies More Likely To Have Flat Spots

Pediatrics News From Medical News Today — Tue, 17 Nov 2009 14:00:00 +0100

Since the American Academy of Pediatrics recommended in 1992 that all infants sleep on their back to reduce the risk of Sudden Infant Death Syndrome, pediatricians have seen an increased number of infants who develop flat spots on the back of their head - a condition called deformational plagiocephaly (DP). In a study, "Risk Factors Associated With Deformational Plagiocephaly," published in the December issue of Pediatrics (appearing online Nov. (Source: Pediatrics News From Medical News Today)

Exergen TemporalScanner Effective In Detecting Fevers In Children Aged 1 - 4 Years, Study Finds

Pediatrics News From Medical News Today — Tue, 17 Nov 2009 09:00:00 +0100

"Temporal artery thermometry is an effective screening tool in identifying fever in children one to four years of age," according to a recent study published in the journal Clinical Pediatrics. The study investigated the sensitivity and specificity of scanning the forehead area to detect temporal artery temperature, as a substitute for rectal temperatures in children 1-4 years old. (Source: Pediatrics News From Medical News Today)

FDA Expands Use Of CSL Limited's Seasonal And H1N1 Vaccines To Infants And Children

Pediatrics News From Medical News Today — Tue, 17 Nov 2009 08:00:00 +0100

The U.S. Food and Drug Administration has approved the use of the CSL Limited's seasonal and 2009 H1N1 influenza vaccines to include children ages 6 months and older. These vaccine were previously approved for use in adults, ages 18 years and older "Because children are among those most vulnerable to the 2009 H1N1 virus, having a broader range of vaccines available for use in children is an important step in responding to the H1N1 outbreak," said Margaret A. Hamburg, M.D. (Source: Pediatrics News From Medical News Today)

Psychologists Welcome Tobacco Curbs In New Health Act

Pediatrics News From Medical News Today — Tue, 17 Nov 2009 08:00:00 +0100

The British Psychological Society welcomes the passage of measures protecting young people from harm caused by tobacco into law in the Health Act 2009. The President of the Society, Sue Gardner, says: "We regard the protection of children and young people from smoking as an extremely high priority. All the available evidence suggests that the earlier young people start to smoke the more difficult they will find it to quit. (Source: Pediatrics News From Medical News Today)

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'Fearless' 3-Year-Olds Might Be Tomorrow's Criminals

MedicineNet Kids Health General — Tue, 17 Nov 2009 07:00:00 +0100

Title: 'Fearless' 3-Year-Olds Might Be Tomorrow's CriminalsCategory: Health NewsCreated: 11/17/2009 8:10:00 AMLast Editorial Review: 11/17/2009 (Source: MedicineNet Kids Health General)

Young Children: Child Development

MedicineNet Kids Health General — Tue, 17 Nov 2009 07:00:00 +0100

Title: Young Children: Child DevelopmentCategory: Health and LivingCreated: 11/17/2009 3:25:00 PMLast Editorial Review: 11/17/2009 3:25:05 PM (Source: MedicineNet Kids Health General)

CKS topic review: Teething

NeLM - Paediatrics — Tue, 17 Nov 2009 00:00:00 +0100

Source: No information given Area: Evidence > Guidelines This Topic Review from the Clinical Knowledge Service (CKS) covers the management of teething in infants under 3 years. (Source: NeLM - Paediatrics)

A stump appendicitis in a child: a case report

Italian Journal of Pediatrics — Tue, 17 Nov 2009 00:00:00 +0100

Conclusions: Stump appendicitis is rare and should be considered in any patient with right lower quadrant pain even if there is a history of appendectomy. Complete removal of the appendix is the only mean to prevent the occurrence of this complication. (Source: Italian Journal of Pediatrics)

Should babies watch videos or tv?

Pediatric Health Associates — Mon, 16 Nov 2009 21:10:00 +0100

You may have heard the recent controversy about “Baby Einstein” videos. Originally touted as educational products for babies, in 2006 the Disney Company stopped marketing the videos as educational. This was due to studies coming out showing that infants and toddlers exposed to daily doses of television has a propensity to develop attention disorders by age 7. Attention disorders include ADHD and ADD, which affects a child’s ability to focus, their attention span, leading them to have learning and behavior disorders.Of concern is children’s perception of events they see on television. When they see violence, do they see that as a normal part of life? Studies have found that violent content, whether a child is directly viewing or just in the room while someone is watching the program...

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Robots in the OR

DukeHealth.org: Duke Health Features — Mon, 16 Nov 2009 19:53:12 +0100

Learn how robots are changing the face of surgery. (Source: DukeHealth.org: Duke Health Features)

Rationing Health Care: Why We Shouldn't Always Get What We Need

DukeHealth.org: Duke Health Features — Mon, 16 Nov 2009 18:26:06 +0100

Bioethicist Gopal Sreenivasan, PhD, asserts that a seemingly severe approach to health care reform -- rationing -- is not only part of a workable solution, but a moral duty. (Source: DukeHealth.org: Duke Health Features)

One son’s story: Getting to know my father thanks to advances in epilepsy medication

Thrive, Children's Hospital Boston — Mon, 16 Nov 2009 18:11:21 +0100

Steve Coldwell and his father, Stephen, in 1974 When I think of my father’s epilepsy, I always go back to a seizure he had during one of my Boy Scout camping trips. It wasn’t the first time I saw my dad have an epileptic seizure, but it was the first time I was the only member of our family around to deal with it. We were playing softball and he was at bat. After a pitch or two went past him, he simply let the bat fall to the ground and sat down on home plate. I immediately knew he was having a seizure, so I helped him up, walked him off the field and talked to him until he came back around. When my mother heard about it later, she was upset, asking why I hadn’t called her after it happened. I told her there was no point. It wasn’t like I had never seen my father have a seizure; t...

Reply

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:16 +0100

To the Editor: Kahn and Courtney have written a Letter to the Editor in response to the recent publication of Gupta et al (and my accompanying editorial) comparing CPAP delivered by Infant Flow Driver with a Bubble CPAP device. The letter raises a few issues pertinent to the debate about the best way to deliver CPAP. (Source: The Journal of Pediatrics)

Reply

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:16 +0100

To the Editor: We thank Kahn and Courtney for their comments. As they note, some studies, including their own, have compared the physiological effects of “continuous flow” with “variable flow” CPAP and shown advantages of the variable flow system. The clinical outcome of interest, however, can only be judged when the devices are used in vivo, and any conclusions of superiority can only be made after studying the safety and long-term outcomes data in human subjects. For instance, despite the stated putative advantages, a large randomized controlled trial comparing “variable flow” CPAP and “continuous flow” ventilator-derived CPAP failed to show any differences in outcomes between the 2 CPAP study groups. (Source: The Journal of Pediatrics)

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Nasal continuous positive airway pressure devices: Separating science from religion

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:16 +0100

To the Editor: We read with great interest the article by Gupta et al comparing bubble continuous positive airway pressure (BCPAP) with Infant Flow Driver CPAP (IFD-CPAP), along with the accompanying editorial by Polin. It is commendable that neonatologists are actively investigating different methods of delivering CPAP, a therapy that we use with regularity. Although the authors found no significant differences between the 2 devices in terms of the primary outcome of extubation failure rate within 72 hours, given what we know about the devices, we are surprised by the large difference in extubation success rates favoring BCPAP in the subgroup ventilated for less than 14 days. In previous randomized trials, compared with continuous-flow CPAP, variable-flow CPAP has afforded improved short...

Reply

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:16 +0100

To the Editor: We appreciate the interest of Ting and Cheung in our report of similar cerebral blood flow velocities in extremely low birth weight (ELBW) infants with and without hypotension (before treatment). We, too, feel that our case-control study provides valuable information to the literature and hope it will aid in the design of a large scale, multi-center trial evaluating the treatment of hypotension (including permissive hypotension) in ELBW infants. As addressed in their letter, it was previously reported that cerebral blood flow (CBF) was reduced in ELBW infants with hypotension. However, the 12 infants with hypertension in the study by Munro et al were approximately 2 weeks more immature (although not statistically significantly different likely because of the smaller sample ...

Cerebral blood flow velocities in extremely low birth weight infants

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:15 +0100

To the Editor: We read with great interest the article of Lightburn et al, which reported similar cerebral blood flow (CBF) velocities of extremely low birth weight (ELBW) infants with and without hypotension. The relationship between low early postnatal CBF and subsequent neurodisability is always the concern of clinicians. Hypotension in ELBW infants during the first postnatal day is not uncommon and may be caused by delayed adaptation of the immature myocardium, the sudden increase in systemic vascular resistance, and/or vasodilatation related to chorioamnionitis and funisitis. Munro et al reported that CBF was reduced in ELBW infants with hypotension, whereas the early neonatal course and the causes of hypotension in these patients were not addressed. The case-control study by Lightb...

Unrecognized Invasive Infection in a Neonate Colonized with Methicillin-Resistant Staphylococcus aureus

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:15 +0100

A 3-month-old, 26-week premature infant presented to a regional hospital with macrocephaly. Head computed tomography revealed abnormal brain with limited cortical tissue, ventriculomegaly, and ring-enhancing foci, prompting referral to our center. Magnetic resonance imaging confirmed extensive cerebral abscesses (). (Source: The Journal of Pediatrics)

An Unusual Case of Cardiomegaly

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:15 +0100

An otherwise healthy 9-year-old boy with a history of asthma was referred to our institution secondary to cardiomegaly observed on a chest radiograph. His history was significant for several weeks of intermittent epigastric pain, 2 days of fever, and mild shortness of breath. Results of his physical examination, routine laboratory data, and electrocardiogram (; available at www.jpeds.com) were within normal limits. His chest radiograph demonstrated severe cardiomegaly and left-sided basilar streaky opacities (). (Source: The Journal of Pediatrics)

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Effective Desensitization to Imiglucerase in a Patient with Type I Gaucher Disease

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:15 +0100

We describe a child who had anaphylactic hypersensitivity to imiglucerase therapy for Gaucher disease. Treatment was stopped and symptoms returned. After immune desensitization to imiglucerase using a rush protocol, the patient was able to resume treatment and has not had further hypersensitivity complications to date. (Source: The Journal of Pediatrics)

Hepatoblastoma in a Patient with Sotos Syndrome

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:15 +0100

We report a case of hepatoblastoma that developed in a child with Sotos syndrome, an overgrowth syndrome with an increased risk of neoplasms. Genome-wide analysis of copy number alterations showed a gain of chromosome 2, uniparental disomy of 18q, and microdeletion of 5q35. (Source: The Journal of Pediatrics)

Neoplasia in Familial Dysautonomia: A 20-Year Review in a Young Patient Population

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:15 +0100

We reviewed the charts of all patients with familial dysautonomia (n = 631) and found that 2% had been diagnosed with tumors. We hypothesize that the IκB Kinase-associated protein gene mutation, which causes aberrant RNA splicing in patients with familial dysautonomia, may contribute to tumorigenesis in this genetically homogenous patient population. (Source: The Journal of Pediatrics)

Pachydermatodactyly Mimics Polyarticular Juvenile Idiopathic Arthritis

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:14 +0100

We report 2 cases erroneously diagnosed as polyarticular juvenile idiopathic arthritis, then referred to pediatric rheumatology for further assessment because of lack of improvement after initial treatment. (Source: The Journal of Pediatrics)

The Importance of Sweat Testing for Older Siblings of Patients with Cystic Fibrosis Identified by Newborn Screening

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:14 +0100

We report cystic fibrosis (CF) care center instructions for sweat testing in older siblings after implementation of the French nationwide newborn screening program, and we evaluate the incidence of unrecognized CF. Nearly 9% of families with an infant screened for CF were unaware of an affected older sibling. We strongly recommend sweat testing for all first-degree older children. (Source: The Journal of Pediatrics)

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Asymptomatic Maternal Combined Homocystinuria and Methylmalonic Aciduria (cblC) Detected through Low Carnitine Levels on Newborn Screening

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:13 +0100

A symptom-free woman gave birth to a girl with a low carnitine level on newborn screening. The baby was unaffected, but the mother had biochemical abnormalities and mutations characteristic of the cblC defect of vitamin B12 metabolism (late-onset form). This patient with cblC was detected through her infant's newborn screening. (Source: The Journal of Pediatrics)

Update on “The Choking Game”

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:03 +0100

This report summarizes the current understanding of a risk-taking behavior by older children and young adolescents. Asphyxial games, often referred to as “the choking game” by the media and in the medical literature, are now a recognized thrill-seeking behavior among young people. Recent reports indicate that knowledge of and participation in such activities is more common than previously recognized by most adults, and that death can occur, particularly when the activity is solitary in nature. Most pediatricians recognize that the behavior itself is not new, but there are critical differences in how this “game” is played by some youth today. (Source: The Journal of Pediatrics)

Treatment of the Patent Ductus Arteriosus: When, How, and for How Long?

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:03 +0100

In the vast majority of neonates, both term and preterm, the decrease in pulmonary vascular resistance after birth reverses the direction of the shunt flow through the ductus arteriosus to primarily left to right. In healthy term neonates, the ductus then closes within the first 2 to 3 postnatal days, but the shunt persists in most of the very preterm infants (≤28 weeks). With the lungs becoming the organ of gas exchange after birth, the systemic and pulmonary circulations separate and the cardiovascular system functions as a circulation in series. Under these circumstances there are no hemodynamic benefits of shunts between the two circulations and therefore a persistent patent ductus arteriosus (PDA) cannot be considered physiological. Indeed, the adverse hemodynamic effects of PDA on ...

Inflaming the Debate on Infant Colic

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:03 +0100

Research in infant colic is beleaguered in its progress toward etiology and subsequent targeted therapy by the lack of a precise definition, relying on pattern recognition from the history, which is usually provided by the infant's mother. Consequently, little reliable and reproducible epidemiology has been generated due to the inevitable variability in reported frequency of the disorder. A systematic review of the frequency of infant colic in community-based prospective and retrospective studies found that the incidence of infant colic ranged widely, from 3% to 40%. Even with the authors selecting studies with the perhaps overly strict diagnostic criteria of Wessel et al, paroxysms of crying of more than 3 hours per day for more than 3 days per week, the reported cumulative incidence of i...

Genes, Environment, Child Care, and Asthma

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

The presence and severity of asthma reflect the interaction between a child's genes and the environment. Twin studies demonstrate convincingly that a child's genetic endowment is the most important predictor of the diagnosis of asthma. Although genetics appears to play the major role in determining asthma, the dramatic increase in the prevalence of childhood asthma over the last 30 years bears testimony to the importance of environmental factors as well. This increase has been too rapid to be explained by genetic drift. Identifying the environmental factor(s) responsible for this change could provide clues to environmental modifications or treatment strategies that might reverse the recent increase in asthma prevalence, perhaps to a level below that before the increase. A particularly popu...

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The Continuing Challenge of “Indeterminate” Acute Liver Failure in Children

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

One of the most challenging problems in pediatric hepatology is the child who presents with acute liver failure (ALF). The barriers to determining a specific diagnosis are multiple and daunting. There is a very limited time frame for completing an evaluation before liver transplantation. Many diagnostic tests for specific causes do not have high sensitivity or specificity and are not standardized across institutions that care for these patients. Liver biopsy is often not possible because of coagulopathy, and transjugular biopsy is often insufficient for a diagnosis. Even adequate tissue sampling often does not yield a specific diagnosis, especially in the presence of massive necrosis and parenchymal collapse. Finally, even after an exhaustive workup is completed, there will still be a sign...

Report on AMSPDC Activities and Initiatives: 2007 to 2009

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

Because so many readers of The Journal are members of academic departments, the leadership of the Association of Medical School Pediatric Department Chairs, Inc (AMSPDC) has decided to use this venue to keep them informed about the activities of the pediatric chairs' group. The past 2 years (2007-2009) have been particularly busy for AMSPDC, with several new initiatives. (Source: The Journal of Pediatrics)

Information for Readers

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

(Source: The Journal of Pediatrics)

Editorial Board

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

(Source: The Journal of Pediatrics)

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

(Source: The Journal of Pediatrics)

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Pulmonary vasodilation with sildenafil in newborns

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

Although inhaled nitric oxide (iNO) is widely used for pulmonary hypertension from multiple causes in newborns, not all patients respond. The iNO works as a vasodilator by increasing cGMP in pulmonary vascular smooth muscle. There are other ways to increase cGMP levels, and one is to prevent degradation of cGMP by inhibition of the type 5 phosphodiesterase in the lung with sildenafil. This drug is available as a pill but not as an intravenous preparation. In this issue of The Journal, Steinhorn et al report a multicenter dose range study of intravenous sildenafil for infants with severe pulmonary hypertension. The infants had a consistent improvement in oxygenation with few side effects. These early results are remarkable because the systemic administration of a vasodilator improved oxygen...

Changing providers is associated with poor asthma control

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

In this issue of The Journal, Dombkowski et al from the University of Michigan have studied the relationship between continuity of medical providers and exacerbations of asthma. The results showed that children with multiple prescribers in different practices had an increased risk of requiring a visit to the emergency room; this relationship was true for those with both high and those with low prescription frequency. The results suggest that relative disorganization of care is associated with poor asthma control. They also show that providers may not be able to identify high risk patients based simply on the number of prescriptions for symptom-relieving medication. (Source: The Journal of Pediatrics)

“Simple dimples” and deviated gluteal folds

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

Pediatricians have been comfortable with assessing as insignificant the common low-lying midline dimple or deviated gluteal folds found at the nursery or first well-infant examination. The current prospective study from Tel Aviv assessed 254 infants less than 6 months of age who were referred for neurosurgical consultation; 154 had these isolated, low-risk skin findings – “simple dimple” (ie, midline, within 2.5 cm of the anus, and with no other abnormality) or deviated gluteal folds (ie, abnormal folds whether bifid, split symmetrically, or asymmetrically without a mass). Of 151 ultrasound examinations performed on these infants, 147 were conclusive and normal, and 4 were inconclusive. Authors conclude that with technical and interpreter expertise, ultrasonography is a sensitive scr...

Early child care exposure and risk of childhood asthma

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

Gurka et al from the University of Virginia recently completed a study of 939 children and their families enrolled in the National Institute of Child Health and Development Study of Early Child Care and Youth Development. They assessed risk factors for persistent or late onset asthma by 15 years of age and found that the number of children in the child care environment when the child was a toddler was significantly associated with the odds of asthma, even after adjusting for respiratory illnesses and other risk factors. The fewer the children exposed to as toddlers, the higher of the probability of persistent or late onset asthma by age 15. This supports the theory of a protective effect of exposure to other children at an early age. (Source: The Journal of Pediatrics)

Pediatric sudden death

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

Sudden death is often thought of as an adult phenomenon, usually the result of cardiovascular disease. However, sudden death does occur in the pediatric age range and may have a variety of causes. Unfortunately, there are fewer population-based data than optimum on this subject. In this issue of The Journal, Wu et al report on a population-based study of pediatric sudden death in Taiwan. They used a National Health Insurance database, and they found that the incidence of sudden death for individuals age 1-18 years was 2.7 / 100 000 person years. Incidence rates reached a peak in infancy, then declined and reached a nadir at 11-12 years of age, and then gradually increased to reach another peak at age 16-18 years. There was also a male predominance for sudden death. These incidence rates re...

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The choking game

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:02 +0100

refers to risk taking behavior by older children and adolescents that involve asphyxia; the name “The Choking Game” has appeared in the media and the medical literature. In this issue of The Journal, Andrew et al present a Medical Progress article concerning this disturbing epidemic. (Source: The Journal of Pediatrics)

Bone marrow transplant for severe combined immunodeficiency

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:01 +0100

In this issue of The Journal, Railey et al report a quarter-century experience at Duke University Medical Center and the long-term outcome of non-ablative bone marrow transplantation for severe combined immunodeficiency (SCID) in a cohort of 161 infants who had related, predominantly non-identical, donors. Outcome at 6 months to 27 years follow-up (mean 8.7 years) showed 77% survival. Critical determinant of survival was early transplant at (Source: The Journal of Pediatrics)

Associations between physical activity, fitness, and academic achievement

The Journal of Pediatrics — Mon, 16 Nov 2009 15:11:01 +0100

The role for physical activity and fitness in the school setting has been controversial. With increasing pressure for children and adolescents to perform better in school, administrators and teachers have often responded by increasing classroom time. Because the time available is finite, this has often resulted in less time spent on physical activity. The reduction in physical education and other activities in school has been cited as one reason for the increasing prevalence of childhood obesity. Others have challenged the concept that more classroom time and less activity will lead to enhanced academic performance. (Source: The Journal of Pediatrics)

Overhaul Could Leave Kids' Hospitals Strapped For Cash

Pediatrics News From Medical News Today — Mon, 16 Nov 2009 10:00:00 +0100

Industry advocates say health reform could place a disproportionate burden on children's hospitals, because they will face cuts along with other hospitals, but do not stand to benefit from expansions in insurance coverage, USA Today reports. Children's hospitals "serve a high share of patients on Medicaid, which pays hospitals less than private insurance. (Source: Pediatrics News From Medical News Today)

'Love Hormone' May Trigger Jealousy, Too

MedicineNet Kids Health General — Mon, 16 Nov 2009 07:00:00 +0100

Title: 'Love Hormone' May Trigger Jealousy, TooCategory: Health NewsCreated: 11/15/2009 8:10:00 AMLast Editorial Review: 11/16/2009 (Source: MedicineNet Kids Health General)

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Kids Kept Indoors Due to Poor Clothing Choices

MedicineNet Kids Health General — Mon, 16 Nov 2009 07:00:00 +0100

Title: Kids Kept Indoors Due to Poor Clothing ChoicesCategory: Health NewsCreated: 11/13/2009 4:10:00 PMLast Editorial Review: 11/16/2009 (Source: MedicineNet Kids Health General)

New Understanding of How the Brain Detects Emotion

MedicineNet Kids Health General — Mon, 16 Nov 2009 07:00:00 +0100

Title: New Understanding of How the Brain Detects EmotionCategory: Health NewsCreated: 11/13/2009 4:10:00 PMLast Editorial Review: 11/16/2009 (Source: MedicineNet Kids Health General)

Another Swine Flu Vaccine Approved for Children

MedicineNet Kids Health General — Mon, 16 Nov 2009 07:00:00 +0100

Title: Another Swine Flu Vaccine Approved for ChildrenCategory: Health NewsCreated: 11/13/2009 4:10:00 PMLast Editorial Review: 11/16/2009 (Source: MedicineNet Kids Health General)

Folic Acid Late in Pregnancy Tied to Asthma in Kids

MedicineNet Kids Health General — Mon, 16 Nov 2009 07:00:00 +0100

Title: Folic Acid Late in Pregnancy Tied to Asthma in KidsCategory: Health NewsCreated: 11/13/2009 2:10:00 PMLast Editorial Review: 11/16/2009 (Source: MedicineNet Kids Health General)

Many Kids Feel Threatened in the Classroom

MedicineNet Kids Health General — Mon, 16 Nov 2009 07:00:00 +0100

Title: Many Kids Feel Threatened in the ClassroomCategory: Health NewsCreated: 11/13/2009 12:10:00 PMLast Editorial Review: 11/16/2009 (Source: MedicineNet Kids Health General)

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Imagination Helps Tame Young Kids' Fears

MedicineNet Kids Health General — Mon, 16 Nov 2009 07:00:00 +0100

Title: Imagination Helps Tame Young Kids' FearsCategory: Health NewsCreated: 11/16/2009 11:51:00 AMLast Editorial Review: 11/16/2009 11:51:02 AM (Source: MedicineNet Kids Health General)

What Types of Community Services Are Available?

PediatricEducation.org — Mon, 16 Nov 2009 00:01:16 +0100

Discussion Health care providers often view the patient through the medical lens and may not see the full view of all aspects of patients and families lives. Even many who work in community centered locations may not be aware of the breadth of services wanted and needed by families. Medical and community services are diverse in every location and often change as funding becomes available or dries up. One of the most difficult tasks for a health care provider (and patients and families) is to move to a new location and need to locate and access various services. Health care providers who take care of patients and families from a wide geographical area are at an additional disadvantage as the practitioner often is not aware of the availability or non-availability of local community services...

Hispanic listeners tune in to support St. Jude

St. Jude Children's Research Hospital — Mon, 16 Nov 2009 00:00:00 +0100

Hispanic radio listeners in more than a dozen cities tuned in to help fight against childhood cancer, raising more than $633,000 in cash and pledges during the second annual "Promesa y Esperanza" (Promise and Hope) radiothon to benefit St. Jude Children’s Research Hospital. (Source: St. Jude Children's Research Hospital)

Smoking cessation program offers childhood cancer survivors help to quit the habit

St. Jude Children's Research Hospital — Mon, 16 Nov 2009 00:00:00 +0100

As health advocates gear up for this year’s Great American Smokeout, childhood cancer survivors who need help with smoking cessation can receive free counseling and nicotine replacement therapy from St. Jude Children’s Research Hospital. (Source: St. Jude Children's Research Hospital)

Hydrogen-ion potential of dobutamine hydrochloride solutions exposed to environmental conditions of neonatal intensive care units.

Jornal de Pediatria — Mon, 16 Nov 2009 00:00:00 +0100

CONCLUSION: There was higher variation in the pH of the solutions exposed to phototherapy, and the use of amber intravenous sets reduced such effect. PMID: 19918623 [PubMed - as supplied by publisher] (Source: Jornal de Pediatria)

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Congenital toxoplasmosis from a chronically infected woman with reactivation of retinochoroiditis during pregnancy - an underestimated event?

Jornal de Pediatria — Mon, 16 Nov 2009 00:00:00 +0100

Authors: Andrade GM, Vasconcelos-Santos DV, Carellos EV, Romanelli RM, Vitor RW, Carneiro AC, Januario JN OBJECTIVE: To report a rare case of congenital toxoplasmosis from an immunocompetent mother with chronic infection who had reactivation of ocular disease during pregnancy. DESCRIPTION: The newborn was asymptomatic at birth and identified by neonatal screening (IgM anti-Toxoplasma gondii in dried blood) among other 190 infants with congenital toxoplasmosis during a 7-month period. His mother had had a non-treated episode of reactivation of toxoplasmic retinochoroiditis during pregnancy, with stable IgG titers and negative IgM results. Results of IgM and IgG in the newborn's serum, as well as IgG immunoblotting were positive and active retinochoroidal lesions were detected in his per...

Hispanic listeners tune in to support St. Jude

St. Jude Children's Research Hospital — Mon, 16 Nov 2009 00:00:00 +0100

Smoking cessation program offers childhood cancer survivors help to quit the habit

St. Jude Children's Research Hospital — Mon, 16 Nov 2009 00:00:00 +0100

Late preterm birth is a risk factor for growth faltering in early childhood: a cohort study

BMC Pediatrics - Latest articles — Mon, 16 Nov 2009 00:00:00 +0100

Conclusions: Late preterm children grow faster than children born at term, but they are at increased risk of underweight and stunting in the first two years of life. Failure to thrive in the first two years may put them at increased risk of future occurrences of serious morbidity in late childhood and of chronic disease development in adult life. (Source: BMC Pediatrics - Latest articles)

This week on Thrive: Nov. 9 – 13

Thrive, Children's Hospital Boston — Sun, 15 Nov 2009 13:00:31 +0100

Here’s a quick look at what Thrive was up to last week. An eco-perspective is explored on H1N1. Survivors of childhood brain cancer face a variety of late effects and why you need to get rid of your old glass thermometers. Children’s explores how babies understand expressions and emotions and offers tips on how to prepare your child for a flu vaccine. A new study reveals that parents are out of touch about knowing their kids’ stress levels and a Children’s expert gives tip on how to help kids cope with the stress of having a parent at war. The HealthMap team gives us our weekly H1N1 update and your questions are answered about whether or not your asthmatic child should get the H1N1 vaccine. Children are increasingly relying on food stamps and the Mediatrician dishes on telenovelas ...

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Health headlines: H1N1 news, yoga for kids and peanut-sniffing dogs

Thrive, Children's Hospital Boston — Sat, 14 Nov 2009 13:00:28 +0100

Other stories we’ve been reading: Educators are turning to yoga to connect with kids, with positive results. Once again, Children’s made the honor roll. We found out that childhood scents occupy a special spot in our brains, and that autistic children often struggle with handwriting. Many adults, including parents and high-priority adults still don’t have access to the H1N1 vaccine. A new experimental drug, Peramivir, is being used in emergencies to treat patients hospitalized with H1N1. College students don’t plan on getting the H1N1 vaccine and at least 540 children have been killed by H1N1 in the United States since April. Man’s best friend is helping out children in all kinds of ways: Dogs are teaching kids to read and are being trained to sniff our peanut products for kids w...

Scientists And Children's Hospice Team Up On Unique Study

Pediatrics News From Medical News Today — Sat, 14 Nov 2009 09:00:00 +0100

A partnership between researchers at the University of Leeds and Martin House Children's Hospice has resulted in the world's first comprehensive study of palliative care received by children and young people. (Source: Pediatrics News From Medical News Today)

Study Aims To Find Fun, Effective Way To Combat Pediatric Obesity

Pediatrics News From Medical News Today — Sat, 14 Nov 2009 09:00:00 +0100

Childhood obesity is on the rise, and with it comes an increased risk for developing health problems such as type 2 diabetes. The best way to reduce the risk of serious weight-related health issues such as diabetes is to eat healthy and increase physical activity. (Source: Pediatrics News From Medical News Today)

Shire Reports Analysis Examining Emotional Lability In Children With ADHD Taking Vyvanse

ADHD News From Medical News Today — Sat, 14 Nov 2009 09:00:00 +0100

In this study, Vyvanse demonstrated significant improvement in Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms as measured by the ADHD Rating Scale IV (ADHD-RS IV) and Connors' Parent Rating Scale-Revised Short (CPRS-RS) in children with ADHD aged 6 to 12 years. (Source: ADHD News From Medical News Today)

Tips On Taming The Boogie Monster

Pediatrics News From Medical News Today — Sat, 14 Nov 2009 08:00:00 +0100

Many parents of preschoolers struggle with their children's fears of real and imaginary creatures. A new study offers some ideas on how they can better manage their children's worries. The study, which was carried out by researchers at the University of California, Davis, appears in the November/December 2009 issue of the journal Child Development. (Source: Pediatrics News From Medical News Today)

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Youths See All Parental Control Negatively When There's A Lot Of It

Pediatrics News From Medical News Today — Sat, 14 Nov 2009 08:00:00 +0100

A new study has found that young people feel differently about two types of parental control, generally viewing a type of control that's thought to be better for their development more positively. However, when parents are very controlling, young people no longer make this distinction and view both types of parental control negatively. (Source: Pediatrics News From Medical News Today)

Diffusion tensor tractography detection of functional pathway for the spread of epileptiform activity between temporal lobe and Rolandic region

Child's Nervous System — Sat, 14 Nov 2009 06:54:27 +0100

Conclusion We have found aberrant tractography pathway traversing through the external capsule, connecting two distant foci of epileptiform activity. Chronic interictal epileptogenic discharge could play a causal role in the de novo organization of these tracts. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00381-009-1017-1Authors Ratan D. Bhardwaj, The Hospital for Sick Children Division of Neurosurgery, Department of Surgery Suite 2608—12 Yonge Street Toronto ON Canada M5E 1Z9Sina Zarei Mahmoodabadi, The Hospital for Sick Children Division of Neuroradiology, Department of Radiology Toronto ON CanadaHiroshi Otsubo, The Hospital for Sick Children Division of Neurology, Department of Pediatrics Toronto ON CanadaO. Carter Snead, The Hospital for Sick ...

Chronic uncal herniation secondary to posterior fossa shunting: case report and literature review

Child's Nervous System — Sat, 14 Nov 2009 06:54:26 +0100

Conclusion We conclude that a negative pressure gradient in the posterior fossa, relative to the supratentorial compartment, is the etiology of the chronic uncal herniation in our patient. Comparing the case reports in the literature with our case, we postulate that chronic uncal herniation is a complication of shunting of a posterior fossa fluid cavity in children, many of them with Dandy–Walker syndrome and/or other cerebellar cystic formations. The treatment priority at presentation should be to rule out shunt malfunction. In the event of association with clinical over-drainage syndrome, there may be a role for changing the shunt system into a more conservative drainage combination. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00381-009-1027-zAut...

Neuroprotective effect of combined hypoxia-induced VEGF and bone marrow-derived mesenchymal stem cell treatment

Child's Nervous System — Sat, 14 Nov 2009 06:54:26 +0100

Conclusions These results suggest that combined pEpo-SV-VEGF and BMSC treatment is effective in protecting neurons against hypoxic ischemic injury. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00381-009-1040-2Authors Sung Su An, Yonsei University Department of Neurosurgery, Spine & Spinal Cord Institute, College of Medicine Seoul 120-752 South KoreaHong Lian Jin, Yonsei University Department of Neurosurgery, Spine & Spinal Cord Institute, College of Medicine Seoul 120-752 South KoreaKeung Nyun Kim, Yonsei University Department of Neurosurgery, Spine & Spinal Cord Institute, College of Medicine Seoul 120-752 South KoreaHyun Ah Kim, Hanyang University Department of Bioengineering, College of Engineering Seoul South KoreaDong Seok Kim, Yonsei University...

Endoscopic third ventriculostomy for obstructive hydrocephalus in children younger than 6 months of age

Child's Nervous System — Sat, 14 Nov 2009 06:54:25 +0100

Conclusions Based on our experience, ETV could be the first method of choice for hydrocephalus in children younger than 6 months of age, especially in patients older than 3 months of age. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00381-009-1019-zAuthors Hideki Ogiwara, Children’s Memorial Hospital Division of Neurosurgery Chicago IL USAArthur J. Dipatri, Children’s Memorial Hospital Division of Neurosurgery Chicago IL USATord D. Alden, Children’s Memorial Hospital Division of Neurosurgery Chicago IL USARobin M. Bowman, Children’s Memorial Hospital Division of Neurosurgery Chicago IL USATadanori Tomita, Children’s Memorial Hospital Division of Neurosurgery Chicago IL USA Journal Child's Nervous SystemOnline ISSN 1433-0350...

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Continuous intrathecal baclofen therapy in children with cerebral palsy – when does improvement emerge?

Acta Paediatrica — Sat, 14 Nov 2009 00:00:00 +0100

Conclusion: There seems to be a sequence of changes after introduction of continuous intrathecal baclofen in a child with cerebral palsy that may guide the multidisciplinary team in their timing of therapy during post-surgical follow-up. (Source: Acta Paediatrica)

How hospitals are keeping up with the surge of H1N1 cases

Thrive, Children's Hospital Boston — Fri, 13 Nov 2009 19:43:04 +0100

Visit msnbc.com for Breaking News, World News, and News about the Economy NBC Nightly News features Children’s in a story about how hospitals are keeping up with treating H1N1. Below, check out more footage of Patty Dauksevicz, RN, discussing how Children’s Emergency Department has seen a 50 percent increase in patients due to H1N1. Visit msnbc.com for Breaking News, World News, and News about the Economy Related posts:Tracking H1N1 in the digital ageNo one’s worried about H1N1?H1N1 (swine flu) weekly highlights: August 21 to 27 (Source: Thrive, Children's Hospital Boston)

Should my asthmatic child get the H1N1 vaccine?

Thrive, Children's Hospital Boston — Fri, 13 Nov 2009 15:33:13 +0100

We’ve received a lot of questions from parents who want to know if the H1N1 vaccine is safe for children with asthma and what complications could result if an asthmatic child is infected with H1N1. We consulted with Children’s Hospital Boston’s associate chief of general pediatrics, Joanne Cox, MD, and reviewed the latest reports from the Centers for Disease Control and Prevention to bring you the most recent information. Is the H1N1 vaccine safe for my child with asthma? Children with asthma or a reactive airways disease should receive the H1N1 vaccine shot, not the H1N1 nasal spray vaccine. The nasal-spray flu vaccine is approved for use only in healthy people 2-49 years of age who are not pregnant. Is my asthmatic child at a higher risk of infection with H1N1? If your ...

Maternal trauma linked to allergy risk in children

MedWire News - Pediatrics — Fri, 13 Nov 2009 15:09:00 +0100

Maternal levels of lifetime interpersonal trauma are associated with cord blood total immunoglobulin E levels in urban newborns, researchers have found. (Source: MedWire News - Pediatrics)

Kids' Health Q&A

DukeHealth.org: Duke Health Features — Fri, 13 Nov 2009 15:06:45 +0100

Duke pediatricians William Lawrence, Martha Gagliano, and Michael Land talk turkey on school lunches, nasty noses, seasonal sneezes, and scabs. (Source: DukeHealth.org: Duke Health Features)

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Kids with CKD Often Have Masked Hypertension (CME/CE)

MedPage Today Pediatrics — Fri, 13 Nov 2009 13:11:08 +0100

Many children with chronic kidney disease may have undetected hypertension, placing them at risk for enlarged hearts and future cardiovascular disease, a cross-sectional study showed. (Source: MedPage Today Pediatrics)

Will watching telenovelas harm my 2 year old?

Thrive, Children's Hospital Boston — Fri, 13 Nov 2009 12:54:22 +0100

Media expert Michael Rich, MD, MPH, director of the Center on Media and Child Health at Children’s Hospital Boston, answers your questions about media use. Last week, he discussed graphic violent and sexual content in the media. Here’s this week’s question: Q: My husband and I immigrated to the United States from the Philippines in 2003, and since then, we had a son, who is now 2. We have The Filipino Channel at home, and my husband and I watch telenovelas and variety shows on that channel all the time. Should we let our son watch with us? I know some telenovelas can be emotional and disturbing. How will I know if they affect him negatively? -Telenovelas at Two in Lubbock, TX A: Dear Telenovelas, It can be challenging for families—including those like yours that have recently ...

Preschoolers Demand Explanations

Pediatrics News From Medical News Today — Fri, 13 Nov 2009 12:00:00 +0100

Curiosity plays a big part in preschoolers' lives. A new study that explored why young children ask so many "why" questions concludes that children are motivated by a desire for explanation. The study, by researchers at the University of Michigan, appears in the November/December 2009 issue of the journal Child Development. (Source: Pediatrics News From Medical News Today)

How Modernization Affects Children's Cognitive Development

Pediatrics News From Medical News Today — Fri, 13 Nov 2009 12:00:00 +0100

Societal and technological changes have taken place at a dizzying pace over recent decades. A new cross-cultural study aimed to determine whether these dramatic changes have had an effect on the thinking skills that are learned over the course of childhood. The study, by researchers at the University of California, Riverside, and Pitzer College, is published in the November/December 2009 issue of the journal Child Development. (Source: Pediatrics News From Medical News Today)

African-American Teens' Mental Health May Be Boosted By Ethnic Pride

Pediatrics News From Medical News Today — Fri, 13 Nov 2009 12:00:00 +0100

Most adolescents who belong to an ethnic minority group wrestle not only with their self-esteem (like most teens), but also with identity issues unique to their ethnic group, such as dealing with social stigma. A new study tells us that young people's ethnic pride may affect their mental health. (Source: Pediatrics News From Medical News Today)

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Awareness Of Racism Affects How Children Do Socially And Academically

Pediatrics News From Medical News Today — Fri, 13 Nov 2009 12:00:00 +0100

This study looked at more than 120 elementary school children from an ethnically and socioeconomically diverse area of the United States. (Source: Pediatrics News From Medical News Today)

Almost 200M Undernourished Children Worldwide, Report Says

Pediatrics News From Medical News Today — Fri, 13 Nov 2009 12:00:00 +0100

In developing countries, almost 200 million children under the age of 5 "suffer from stunted growth and health problems due to poor nutrition in their early years," according to a UNICEF report released on Wednesday, Reuters reports. (Source: Pediatrics News From Medical News Today)

Shire Reports Findings From An Analysis Examining Emotional Lability In Children With ADHD Taking Vyvanse(R) (lisdexamfetamine Dimesylate) Capsules

ADHD News From Medical News Today — Fri, 13 Nov 2009 09:00:00 +0100

Reduced basal salivary cortisol in children with asthma and allergic rhinitis

Acta Paediatrica — Fri, 13 Nov 2009 00:00:00 +0100

Conclusion: Asthmatic children on moderate or high doses of inhaled corticosteroids had reduced salivary cortisol, but co-morbidity of asthma and rhinitis was also associated with reduced cortisol levels. (Source: Acta Paediatrica)

Length of the treatment and number of doses per day as major determinants of child adherence to acute treatment

Acta Paediatrica — Fri, 13 Nov 2009 00:00:00 +0100

Conclusion: This study suggests that simplifying treatment schedules is an effective strategy for improving compliance in paediatric emergency departments. (Source: Acta Paediatrica)

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Neonatal alloimmune thrombocytopenia caused by anti-HLA-A24 alloantibodies

Acta Paediatrica — Fri, 13 Nov 2009 00:00:00 +0100

Conclusion: This case supports the idea that some anti-HLA class I antibodies could cause NAIT. (Source: Acta Paediatrica)

Announcements

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Erratum

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Erratum

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Congenital upper thoracic spondyloptosis with multiple other associated anomalies

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

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Fatal degeneration of specialized cardiac muscle associated with chronic active Epstein–Barr virus infection

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Oral megadose methylphenidate ingestion for suicide attempt

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Diagnostic and therapeutic value of naloxone after intoxication with tramadol in a young girl

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Successful bone marrow transplantation in chronic granulomatous disease

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Acute renal failure caused by fungus balls in renal pelvises

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

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Congenital systemic juvenile xanthogranuloma with placental lesion

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Hajdu–Cheney syndrome: Infantile onset of hydrocephalus and serpentine fibulae

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Bilateral basal ganglia infarction after mild head trauma

Pediatrics International — Fri, 13 Nov 2009 00:00:00 +0100

(Source: Pediatrics International)

Influenza B-associated rhabdomyolysis in Taiwanese children

Acta Paediatrica — Fri, 13 Nov 2009 00:00:00 +0100

Aim: Influenza B-associated rhabdomyolysis (IBAR) is an infrequent and little-known complication of influenza B virus infection in children. Diagnosis is usually made based on clinical history, the presence of influenza in the community and detection of virus in nasopharyngeal specimens. The aim of this study was to describe the clinical and laboratory manifestations, complications and outcomes of IBAR in Taiwanese children.Methods: A retrospective analysis was conducted in patients aged (Source: Acta Paediatrica)