MedWorm: Psychiatry Top 20

Science News » Atypical antipsychotic more effective than older drugs in treating childhood mania, but side effects can be serious

National Institute of Mental Health — Thu, 12 Jan 2012 13:39:49 +0100

The antipsychotic medication risperidone is more effective for initial treatment of mania in children diagnosed with bipolar disorder compared to other mood stabilizing medications, but it carries the potential for serious metabolic side effects, according to an NIMH-funded study published online ahead of print January 2, 2012, in the Archives of General Psychiatry. (Source: National Institute of Mental Health)

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Completed suicide, ideation and attempts in Attention Deficit Hyperactivity Disorder

Acta Psychiatrica Scandinavica — Thu, 12 Jan 2012 13:31:57 +0100

(Source: Acta Psychiatrica Scandinavica)

Seizure risk increased before and after psychiatric hospitalization

MedWire News - Bipolar Disorder — Wed, 01 Feb 2012 10:50:57 +0100

Results from a Swedish study suggest the risk for unprovoked epileptic seizures is significantly increased before and after hospitalization for psychiatric disorders. (Source: MedWire News - Bipolar Disorder)

Functional impairments persist in remitted BD patients

MedWire News - Psychiatry — Mon, 16 Jan 2012 17:41:02 +0100

A significant proportion of bipolar disorder patients who receive specialized mental health care achieve symptomatic recovery, but functional recovery is much less common, study results show. (Source: MedWire News - Psychiatry)

The Brown University Psychopharmacology Update — Thu, 19 Jan 2012 14:48:44 +0100

AbstractNo Increased Risk of Serious Cardiovascular Events with ADHD Drugs in Children or AdultsZolpidem Safe for Long‐Term Use in Physically and Mentally Healthy PatientsMirtazapine Reduces Methamphetamine Use and Sexual Risk Behavior in Men Who Have Sex with MenMaintenance Treatment of Bipolar I DisorderWhy Psychiatrists Should Treat SmokingIncreased Risks of Suicidal Behavior and Depression with Varenicline in Smoking CessationMortality in Antipsychotic‐Induced Neuroleptic Malignant SyndromeDelirium Following Addition of Adjunctive Quetiapine/Valproate in BPRecommendations Unchanged on ADHD DrugsSSRIs in Pregnancy: No Change in RecommendationsNew ApprovalsSafety Labeling Changes (Source: The Brown University Psychopharmacology Update)

Differential neural activation patterns in children with BD and SMD

MedWire News - Psychiatry — Thu, 19 Jan 2012 14:51:03 +0100

Neural activation patterns differ between children with bipolar disorder and those with severe mood dysregulation during a motor inhibition task, researchers have found. (Source: MedWire News - Psychiatry)

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Symptom-specific associations between low cortisol responses and functional somatic symptoms: The TRAILS study

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Conclusion: Two clusters of FSS are differentially associated with the stress hormone cortisol. (Source: Psychoneuroendocrinology)

Science News » Gene Regulator in Brain’s Executive Hub Tracked Across Lifespan – NIH study

National Institute of Mental Health — Sat, 04 Feb 2012 14:45:47 +0100

For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain’s executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia and autism turn out to be members of a select club of genes in which regulatory activity peaks during an environmentally-sensitive critical period in development. (Source: National Institute of Mental Health)

Temperaments linked to clinical features and course in bipolar I disorder

MedWire News - Psychiatry — Tue, 07 Feb 2012 14:12:28 +0100

Research suggests that cyclothymic and hyperthymic temperaments are associated with differences in clinical features in patients with bipolar I disorder, such as number of hospitalizations, disease course, family history, and comorbid disorders. (Source: MedWire News - Psychiatry)

Commentary: Translating quantitative genetics into molecular genetics: decoupling reading disorder and ADHD – reflections on Greven et al. and Rosenberg et al. (2012)

Journal of Child Psychology and Psychiatry — Sun, 22 Jan 2012 15:27:52 +0100

(Source: Journal of Child Psychology and Psychiatry)

Vascular function ‘not impaired’ in young BD patients

MedWire News - Bipolar Disorder — Wed, 25 Jan 2012 16:39:02 +0100

US researchers have found no evidence for impaired vascular function among relatively young patients with bipolar disorder. (Source: MedWire News - Bipolar Disorder)

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Impact of childhood life events and trauma on the course of depressive and anxiety disorders

Acta Psychiatrica Scandinavica — Wed, 25 Jan 2012 16:29:22 +0100

Conclusion: Childhood trauma, but not childhood life events, was associated with an increased persistence of comorbidity and chronicity in adults with anxiety and/or depressive disorders. More unfavourable clinical characteristics at baseline mediate the relationship between childhood trauma and a poorer course of depressive and anxiety disorders. (Source: Acta Psychiatrica Scandinavica)

Psychosocial functioning reduced in multiple-episode BD patients

MedWire News - Psychiatry — Wed, 01 Feb 2012 10:50:58 +0100

Patients with bipolar disorder who have experienced multiple mood episodes show poorer psychosocial functioning over time than first-episode patients, Spanish study results show. (Source: MedWire News - Psychiatry)

Genomic Tics in Tourette Syndrome

Biological Psychiatry — Tue, 07 Feb 2012 14:12:03 +0100

It is a striking observation that studies of copy number variation (CNV) in neurodevelopmental phenotypes continue to report an excess of rare variants in case populations. This astonishing result has been observed and replicated in studies of intellectual disability (), autism (), schizophrenia (), and epilepsy (). In a study published this month in Biological Psychiatry, Tourette syndrome (TS) is now added to this growing list (). (Source: Biological Psychiatry)

Antidepressants and Sleep: Neurophysiology and Clinical Correlates

Current Psychiatry Reviews — Mon, 16 Jan 2012 17:41:36 +0100

(Source: Current Psychiatry Reviews)

Chinese version of MDQ effective for BD screening

MedWire News - Bipolar Disorder — Tue, 07 Feb 2012 14:12:27 +0100

The Chinese version of the Mood Disorder Questionnaire is an effective screening tool for bipolar disorder among patients who have experienced a major depressive episode, say researchers. (Source: MedWire News - Bipolar Disorder)

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ADHD Drug Rarely Prompts ECG Screen (CME/CE)

MedPage Today Psychiatry — Mon, 16 Jan 2012 04:01:00 +0100

(MedPage Today) -- Most pediatricians skip the ECG before starting kids on stimulant medication for attention-deficit hyperactivity disorder, a survey suggested. (Source: MedPage Today Psychiatry)

Customized adherence enhancement for individuals with bipolar disorder receiving antipsychotic therapy

NeLM - Mental Health — Tue, 07 Feb 2012 05:00:00 +0100

Source: Psychiatric Services Area: Evidence > Medicines Management > References Objective: A 3-month prospective trial of a psychosocial intervention - customised adherence enhancement (CAE) - was conducted with 43 medication-nonadherent individuals with bipolar disorder. Methods: CAE modules were administered as indicated by a screen that identifies reasons for nonadherence. The primary outcome was change in adherence to mood-stabilising medications as measured by the Tablet Routines Questionnaire and pill counts. Secondary outcomes included change in symptoms, measured by the Hamilton Rating Scale for Depression (HAM-D), Young Mania Rating Scale (YMRS), and Brief Psychiatric Rating Scale (BPRS). Results: Participants completed 76% of sessions. ...

Electroconvulsive Therapy

About.com Bipolar Disorder — Mon, 16 Jan 2012 05:00:00 +0100

Electroconvulsive therapy or ECT is a treatment in which a convulsion is produced by passing an electric current through the brain. More ... (Source: About.com Bipolar Disorder)

Australian study links diet with anxiety

ANXIETY UK News — Wed, 25 Jan 2012 16:39:43 +0100

A change to your diet could be the step you need to take to improve your state of mind. A study conducted by Dr Felice Jacka in Australia has shown that what we eat can have a profound effect on our mental health in the long term, reducing the risk of depression and anxiety. Dr [...] (Source: ANXIETY UK News)

MedWorm: Psychiatry Top 20

Science News » Atypical antipsychotic more effective than older drugs in treating childhood mania, but side effects can be serious

Completed suicide, ideation and attempts in Attention Deficit Hyperactivity Disorder

Seizure risk increased before and after psychiatric hospitalization

Functional impairments persist in remitted BD patients

Table of Contents

Differential neural activation patterns in children with BD and SMD

Symptom-specific associations between low cortisol responses and functional somatic symptoms: The TRAILS study

Science News » Gene Regulator in Brain’s Executive Hub Tracked Across Lifespan – NIH study

Temperaments linked to clinical features and course in bipolar I disorder

Commentary: Translating quantitative genetics into molecular genetics: decoupling reading disorder and ADHD – reflections on Greven et al. and Rosenberg et al. (2012)

Vascular function ‘not impaired’ in young BD patients

Impact of childhood life events and trauma on the course of depressive and anxiety disorders

Psychosocial functioning reduced in multiple-episode BD patients

Genomic Tics in Tourette Syndrome

Antidepressants and Sleep: Neurophysiology and Clinical Correlates

Chinese version of MDQ effective for BD screening

ADHD Drug Rarely Prompts ECG Screen (CME/CE)

Customized adherence enhancement for individuals with bipolar disorder receiving antipsychotic therapy

Electroconvulsive Therapy

Australian study links diet with anxiety