MedWorm: Psychiatry

ISPNE Call for Abstracts

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

(Source: Psychoneuroendocrinology)

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ISPNE Conference Announcement

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

(Source: Psychoneuroendocrinology)

2012 Curt P. Richter Award of the International Society of Psychoneuroendocrinology (ISPNE)

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

(Source: Psychoneuroendocrinology)

Erratum to “Acknowledgement to Reviewers” [Psychoneuroendocrinology 37 (2012) I–VI]

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

The publisher regrets that A. Leslie Morrow, United States, was accidentally omitted from the list of reviewers. The publisher would like to apologise for any inconvenience caused. (Source: Psychoneuroendocrinology)

The steroid/peptide theory of social bonds: A reply to Goodson's Letter to the Editor

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

We welcome Dr. Goodson's response to our Steroid/Peptide (S/P) Theory of Social Bonds (2011, Psychoneuroendocrinology 36, 1365–1375) and appreciate the venue for additional discussion. We hope to clarify possible misreadings and foster dialogue about our differing levels of analysis. (Source: Psychoneuroendocrinology)

Nonapeptides are not just for bonding: A response to van Anders et al. (2011)

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Nonapeptides (vasopressin, oxytocin, and homologues) broadly influence vertebrate social behavior, and the functions of nonapeptides and sex steroid hormones are extensively intertwined. In an effort to synthesize the nonapeptide and hormone literatures, van Anders et al. (2011, Psychoneuroendocrinology 36: 1365–1375) recently proposed a “steroid/peptide theory of social bonding.” This ambitious undertaking included the proposition of a model that predicts the release of nonapeptides and testosterone in relation to a variety of stimuli, and predicts the downstream effects on social bonding. (Source: Psychoneuroendocrinology)

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A sniff of trust: Meta-analysis of the effects of intranasal oxytocin administration on face recognition, trust to in-group, and trust to out-group

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Summary: The neuropeptide oxytocin has a popular reputation of being the ‘love’ hormone. Here we test meta-analytically whether experiments with intranasal administration of oxytocin provide support for the proposed effects of oxytocin. Three psychological effects were subjected to meta-analysis: facial emotion recognition (13 effect sizes, N=408), in-group trust (8 effect sizes, N=317), and out-group trust (10 effect sizes; N=505). We found that intranasal oxytocin administration enhances the recognition of facial expressions of emotions, and that it elevates the level of in-group trust. The hypothesis that out-group trust is significantly decreased in the oxytocin condition was not supported. It is concluded that a sniff of oxytocin can change emotion perception and behavior in trust...

Regulation of corticoid and serotonin receptor brain system following early life exposure of glucocorticoids: Long term implications for the neurobiology of mood

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Summary: Potent glucocorticoids (GC) administered early in life have improved premature infant survival dramatically. However, these agents may increase the risk for physical, neurological and behavior alterations. Anxiety, depression and attention difficulties are commonly described in adolescent and young adult survivors of prematurity. In the present study we administered vehicle, dexamethasone, or hydrocortisone to Sprague-Dawley rat pups on postnatal days 5 and 6, mimicking a short term clinical protocol commonly used in human infants. Two systems that are implicated in the regulation of stress and behavior were assessed: the limbic–hypothalamic–pituitary–adrenal axis [LHPA; glucocorticoid and mineralocorticoid receptors within] and the Serotonin (5-HT) system. We found that as ...

Periodic maternal separation decreases hippocampal neurogenesis without affecting basal corticosterone during the stress hyporesponsive period, but alters HPA axis and coping behavior in adulthood

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Summary: Although not directly evaluated, the early rise of glucocorticoid (GC) levels, as occur after exposure to adverse early life experience, are assumed to affect hippocampal ontogeny by altering the hippocampus negative feedback on adult HPA axis. To test whether hippocampal ontogeny is affected by early exposure to stress we estimated the survival of recently formed hippocampal granule cells in rat pups subjected to periodic maternal separation (180min/day; MS180) from postnatal days (PND) 1 to 14. Accordingly, MS180 pups injected with bromodeoxyuridine (BrdU, 50mg/kg, ip) at PND 5 showed decreased density of doublecortin (DCX) positive BrdU-labeled cells at PND 15. MS180 and AFR pups showed similar corticosterone (CORT) basal levels between PND 3 and 12, whereas adult MS180 rats pr...

Effects of testosterone on attention and memory for emotional stimuli in male rhesus monkeys

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Summary: Increasing evidence in humans and other animals suggests that testosterone (T) plays an important role in modulating emotion. We previously reported that T treatment in rhesus monkeys undergoing chemically induced hypogonadism results in increased watching time of videos depicting fights between unfamiliar conspecifics (). In the current study, we aimed to further investigate the effect of T manipulations on attention and memory for emotional stimuli in male rhesus monkeys. Six males (7 years old) were administered Depot Lupron to suppress endogenous T levels and treated with either testosterone enanthate (TE, 5mg/kg) or oil, before crossing over to the alternate treatment. Animals were tested for 16 weeks on two computerized touchscreen tasks with both social and nonsocial emotio...

Mouse females devoid of exposure to males during fetal development exhibit increased maternal behavior

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Summary: Many sex differences can be found in the expression of aggression and parental nurturing behaviors. It is important to determine if these are modulated by prenatal conditions. Here, using assisted reproduction technologies, we generated females that were (mixed-sex) or were not (same-sex) exposed to males during fetal development, raised them by cross fostering among fosters’ own female only pups to control for effects of postnatal environment, and compared their reproductive abilities and behavior. There were no differences between females from the two prenatal conditions in estrus cycle length and length of time spent at individual estrus cycle stages. Both types of females had similar ovulation efficiency and bred equally well yielding comparable litter size and progeny sex r...

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Interactive effects of estrogen and serotonin on brain activation during working memory and affective processing in menopausal women

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

We examined the individual and combined effects of estradiol and serotonin on working memory, emotion processing and task-related brain activation. Eight healthy predominantly early postmenopausal women underwent TD or sham depletion followed by functional magnetic resonance imaging (fMRI) both before and after short-term transdermal estradiol 75–150μg/d administration. There was an estradiol treatment by TD interaction for brain activation during performance on both the N-back Task (working memory) and Emotion Identification Task (affective processing). During the 2-back condition, TD attenuated activation prior to, but not after, estradiol treatment in the right and left dorsal lateral prefrontal and middle frontal/cingulate gyrus. During emotion identification, TD heightened activati...

Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

In this study, we examined whether TOMM40 variants, which have been reported to influence age of onset of AD, also had an effect on CSF cortisol levels, in healthy, cognitively intact individuals with or without APOE ɛ4. In our results, the increase in CSF cortisol associated with the presence of the APOE ɛ4 allele was only detected when a short TOMM40 poly-T variant, shown to associate with later age of onset of AD in ɛ4 carriers, was not present. These results are consistent with previous reports (e.g., ) suggesting that TOMM40 poly-T variants influence the effects of APOE alleles. (Source: Psychoneuroendocrinology)

AMPK γ2 subunit gene PRKAG2 polymorphism associated with cognitive impairment as well as diabetes in old age

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Summary: Metabolic and cognitive disorders are closely related. However, the molecular mechanism underlying this association is still elusive. Given the importance of energy metabolism in neuronal cells, AMP-activated protein kinase (AMPK), a master switch of energy metabolism, could be an independent factor affecting cognitive as well as metabolic functions. Therefore, we examined the relationship between the AMPK γ2 gene, the PRKAG2 −26C/T polymorphism and cognitive impairment or diabetes in 1609 subjects aged from 60 to 80. We performed multivariate logistic regression analyses with adjustment for age, gender, education, smoking, alcohol, depression, waist circumference, APOE e4, and stroke history. We found a significant association between the −26C/T polymorphism (CC vs. CT/TT) a...

Neuroendocrine response to CRF stimulation in veterans with and without PTSD in consideration of war zone era

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Conclusions: A uniform pattern of PTSD-related alterations in the response to intravenous CRF was not found. Rather, PTSD-related alterations were found only in veterans of the 1991 Gulf War, and were characterized by an enhanced pituitary response to CRF which may reflect increased sensitivity of pituitary corticotrophs or CRF hyposecretion. Together with previous neuroendocrine findings, the data suggest the HPA axis is dysregulated in Gulf War veterans in unique ways which may reflect the long-term effects of environmental exposures in addition to disease effects. Further work is needed to characterize these effects and their impact on long-term psychological and medical outcomes. (Source: Psychoneuroendocrinology)

Ageing, physical function, and the diurnal rhythms of cortisol and dehydroepiandrosterone

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

In conclusion, this study suggests an association between cortisol, DHEA, ageing and physical function. (Source: Psychoneuroendocrinology)

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Symptom-specific associations between low cortisol responses and functional somatic symptoms: The TRAILS study

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Conclusion: Two clusters of FSS are differentially associated with the stress hormone cortisol. (Source: Psychoneuroendocrinology)

Adulthood trauma and HPA-axis functioning in healthy subjects and PTSD patients: A meta-analysis

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Conclusion: Neither adulthood trauma exposure nor PTSD were associated with differences in HPA-axis functioning, although adulthood trauma may augment cortisol suppression after the DST. More evidence on other dynamic tests of HPA-axis functioning in PTSD and adulthood trauma exposure is needed. (Source: Psychoneuroendocrinology)

Acute and chronic stress induced changes in sensitivity of peripheral inflammatory pathways to the signals of multiple stress systems – 2011 Curt Richter Award Winner

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

Summary: Exposure to psychosocial stress has been associated with increasing rates of morbidity in humans and in animal models, but the underlying mechanisms are not completely understood. Major stress responsive systems, such as the hypothalamus-pituitary adrenal (HPA) axis and the autonomic nervous system (ANS) are under investigation as underlying pathways, but although acute stress reliably activates these systems, findings of long-term alternations in baseline activity are inconsistent at present. Emerging evidence suggests that stress-related changes in the sensitivity of target systems toward glucocorticoid (GC) regulation, i.e. development of GC resistance, might help explain inflammatory disinhibition and development of disease related to inflammation. More recent findings further...

Editorial Board

Psychoneuroendocrinology — Tue, 07 Feb 2012 14:13:24 +0100

(Source: Psychoneuroendocrinology)

Anxiety UK is seeking a Peer M…

ANXIETY UK News — Tue, 07 Feb 2012 14:13:16 +0100

Anxiety UK is seeking a Peer Mentoring Project Coordinator. To find out more & apply, visit http://t.co/QpYEFkxo (Source: ANXIETY UK News)

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Depression symptoms common in schizophrenia patients

MedWire News - Schizophrenia — Tue, 07 Feb 2012 14:12:28 +0100

Clinically relevant symptoms of depression are common in schizophrenia patients who have not been diagnosed with the mood disorder, results from a Spanish study suggest. (Source: MedWire News - Schizophrenia)

Temperaments linked to clinical features and course in bipolar I disorder

MedWire News - Psychiatry — Tue, 07 Feb 2012 14:12:28 +0100

Research suggests that cyclothymic and hyperthymic temperaments are associated with differences in clinical features in patients with bipolar I disorder, such as number of hospitalizations, disease course, family history, and comorbid disorders. (Source: MedWire News - Psychiatry)

Chinese version of MDQ effective for BD screening

MedWire News - Bipolar Disorder — Tue, 07 Feb 2012 14:12:27 +0100

The Chinese version of the Mood Disorder Questionnaire is an effective screening tool for bipolar disorder among patients who have experienced a major depressive episode, say researchers. (Source: MedWire News - Bipolar Disorder)

Manuscript Submission Form

Biological Psychiatry — Tue, 07 Feb 2012 14:12:03 +0100

This form should be completed by every author and accompany every new manuscript submission. It must be fully complete and accurate, with signatures from ALL authors, before a manuscript can be finalized. Please scan the completed form(s) and attach them electronically during the submission process. If you are unable to do so, fax the completed form(s) to the Editorial Office at (214) 645-9208. (Source: Biological Psychiatry)

Guide for Authors

Biological Psychiatry — Tue, 07 Feb 2012 14:12:03 +0100

Biological Psychiatry is the official journal of the Society of Biological Psychiatry. The Journal rapidly publishes reports of novel results on a broad range of topics related to the pathophysiology and treatment of major neuropsychiatric disorders. Both basic and clinical neuroscience contributions are encouraged, particularly those addressing genetic and environmental risk factors, neural circuitry and neurochemistry, and important new therapeutic approaches. Except where explicitly stated otherwise, Biological Psychiatry conforms to the guidelines set forth by the International Committee of Medical Journal Editors (ICMJE) (see Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writing and Editing for Biomedical Publication (April 2010): Available from http://www.ICM...

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Biological Psychiatry — Tue, 07 Feb 2012 14:12:03 +0100

(Source: Biological Psychiatry)

Subscribers Page

Biological Psychiatry — Tue, 07 Feb 2012 14:12:03 +0100

Biological Psychiatry (ISSN 0006-3223) is published semimonthly by Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710. Periodicals postage paid at New York, NY and additional mailing offices. (Source: Biological Psychiatry)

Editorial Board

Biological Psychiatry — Tue, 07 Feb 2012 14:12:03 +0100

(Source: Biological Psychiatry)

Genomic Tics in Tourette Syndrome

Biological Psychiatry — Tue, 07 Feb 2012 14:12:03 +0100

It is a striking observation that studies of copy number variation (CNV) in neurodevelopmental phenotypes continue to report an excess of rare variants in case populations. This astonishing result has been observed and replicated in studies of intellectual disability (), autism (), schizophrenia (), and epilepsy (). In a study published this month in Biological Psychiatry, Tourette syndrome (TS) is now added to this growing list (). (Source: Biological Psychiatry)

A brief summary of the articles appearing in this issue of Biological Psychiatry

Biological Psychiatry — Tue, 07 Feb 2012 14:12:03 +0100

Studies of copy number variation (CNV) have pointed to areas of the genome and biological pathways involved in several neuropsychiatric disorders. In a CNV study of Tourette syndrome (TS) subjects and controls, Fernandez et al. (pages 392–402) report evidence supporting recent findings implicating histaminergic and gamma-aminobutyric acidergic mechanisms in the etiology of TS, as well as an overlap of rare CNVs in TS and autism spectrum disorders (ASDs). (Source: Biological Psychiatry)

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Parental depressive symptoms and children’s sleep: the role of family conflict

Journal of Child Psychology and Psychiatry — Tue, 07 Feb 2012 14:06:06 +0100

Conclusions: Findings build on this scant literature and highlight the importance of identifying pathways of risk and familial and environmental influences on children’s sleep problems. (Source: Journal of Child Psychology and Psychiatry)

The Invisible Disease Depression

About.com Mental Health — Tue, 07 Feb 2012 05:00:00 +0100

Research information on Depression, Dysthymia, and Affective Disorders (Source: About.com Mental Health)

Exercise Can Help Depression in Those With Chronic Illness

About.com Depression — Tue, 07 Feb 2012 05:00:00 +0100

If you have a chronic illness and are battling depression, exercise may be just what you need to lift your mood, according to University of Alabama, Birmingham researchers. For the study, Matthew Herring and his team examined 90 previous studies of 10,500 sedentary patients with chronic illness. Each study included people who had been randomly assigned to either an exercise group or a non-exercise group. In addition, the study participants had had their depression levels measured both before and after exercise....Read Full Post (Source: About.com Depression)

Drug Development in Pediatric Psychiatry: Current Status, Future Trends

Child and Adolescent Psychiatry and Mental Health — Tue, 07 Feb 2012 05:00:00 +0100

n/a (Source: Child and Adolescent Psychiatry and Mental Health)

The acute effects of kava and oxazepam on anxiety, mood, neurocognition; and genetic correlates: a randomized, placebo‐controlled, double‐blind study

Human Psychopharmacology: Clinical and Experimental — Tue, 07 Feb 2012 05:00:00 +0100

ConclusionAcute “medicinal level” doses of this particular kava cultivar in naive users do not provide anxiolytic activity, although the phytomedicine also appears to have no negative effects on cognition. Copyright © 2012 John Wiley & Sons, Ltd. (Source: Human Psychopharmacology: Clinical and Experimental)

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The game's afoot: seeking viruses that cause chronic and degenerative neurologic and psychiatric disorder

Molecular Psychiatry — Tue, 07 Feb 2012 05:00:00 +0100

Molecular Psychiatry advance online publication, February 7, 2012. doi:10.1038/mp.2012.5 Author: M B A Oldstone (Source: Molecular Psychiatry)

Concordance between psychotropic prescribing for Veterans with PTSD and clinical practice guidelines

NeLM - Mental Health — Tue, 07 Feb 2012 05:00:00 +0100

This study aimed to determine which characteristics of veterans with diagnosed PTSD were associated with receiving prescriptions for benzodiazepines and mood stabilisers and second-generation antipsychotics. Methods: The survey responses of 482 veterans with PTSD were combined with prescription information from the US Veterans Affairs national pharmacy databases. The researchers assessed the use of eight classes of psychotropics prescribed for patients with PTSD in the year after a new PTSD diagnosis. Multivariate logistic regressions identified demographic ... (Source: NeLM - Mental Health)

Customized adherence enhancement for individuals with bipolar disorder receiving antipsychotic therapy

NeLM - Mental Health — Tue, 07 Feb 2012 05:00:00 +0100

Source: Psychiatric Services Area: Evidence > Medicines Management > References Objective: A 3-month prospective trial of a psychosocial intervention - customised adherence enhancement (CAE) - was conducted with 43 medication-nonadherent individuals with bipolar disorder. Methods: CAE modules were administered as indicated by a screen that identifies reasons for nonadherence. The primary outcome was change in adherence to mood-stabilising medications as measured by the Tablet Routines Questionnaire and pill counts. Secondary outcomes included change in symptoms, measured by the Hamilton Rating Scale for Depression (HAM-D), Young Mania Rating Scale (YMRS), and Brief Psychiatric Rating Scale (BPRS). Results: Participants completed 76% of sessions. ...

Smoking Speeds Up Male Cognitive Decline

Health News from Medical News Today — Tue, 07 Feb 2012 03:00:00 +0100

A male regular smoker has a higher risk of rapid cognitive decline, compared to his counterparts who do not smoke, researchers from University College London, England, reported in Archives of General Psychiatry. The authors add that the evidence has been mounting regarding the link between smoking and dementia in elderly individuals - smoking has been found to push up the total number of patients with dementia around the world. SÃ©verine Sabia, Ph.D., and team set out to determine what impact smoking might have on men during their transition from middle age to old age... (Source: Health News from Medical News Today)

Free Depression Screening

About.com Depression — Tue, 07 Feb 2012 00:00:51 +0100

Do you believe that the symptoms you are experiencing could be caused by depression? Our online depression screening tool is quick, easy and completely confidential. Try it now! (Source: About.com Depression)

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General visual processing deficits may underlie social difficulties in schizophrenia

MedWire News - Psychiatry — Tue, 07 Feb 2012 00:00:00 +0100

Patients with schizophrenia respond more slowly and less appropriately to face, body, and car images than do healthy individuals, reports a German research team. (Source: MedWire News - Psychiatry)

Antidepressants May Not Raise Suicide Risk in Youth: Study

The Doctors Lounge - Psychiatry — Mon, 06 Feb 2012 22:00:00 +0100

Despite 'black box warning' for drugs such as Prozac, no increase -- or decrease -- was found (Source: The Doctors Lounge - Psychiatry)

Impaired memory following repeated pentylenetetrazol treatments in kindled mice.

Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan — Mon, 06 Feb 2012 21:06:03 +0100

Authors: Takechi K, Suemaru K, Kawasaki H, Araki H Abstract Epilepsy is characterized by recurrent seizures, which are caused by excessive discharges from cerebral neurons. Currently, antiepileptic drugs that possess sodium channel blocking activities and also mediate GABA-ergic systems are primarily used to prevent epileptic seizure. However, approximately 40% of patients with epilepsy suffer from interictal psychiatric comorbidities in clinical practice. Furthermore, it is unclear whether epilepsy is associated with psychic function. The aim of the present study was to clarify the effects of kindling-induced epileptic seizures on psychic functioning using behavioral pharmacological tests. Pentylenetetrazol (PTZ)-kindled mice demonstrated no significant differences in locomotor ac...

The Gentle Self: How to Overcome Your Difficulties with Depression, Anxiety, Shyness, and Low Self-Esteem

Psych Central — Mon, 06 Feb 2012 20:35:16 +0100

I think everyone’s a little narcissistic. We all have moments when we wish everyone would be more like us—when we get upset that no one seems to care about what we are feeling. We also often put others ahead of ourselves and deny ourselves the satisfaction of saying “I need to do this for me.” If either of these becomes an extreme, psychologists may diagnose it as Narcissistic Personality Disorder. The Gentle Self by Gerti Schoen addresses the second type of narcissist. Drawing on her own experiences and her observations of others, Schoen explains exactly what a “gentle self” is. This type of narcissist puts others ahead of themselves because the narcissist feels that he or she is unworthy of love or respect. I can definitely relate to the gentle self. Schoen spen...

Psych Signs Common in Kids With HIV (CME/CE)

MedPage Today State Required CME — Mon, 06 Feb 2012 20:13:13 +0100

(MedPage Today) -- In a snapshot study of children and adolescents with HIV, about a third met criteria for at least one psychiatric disorder, researchers reported. (Source: MedPage Today State Required CME)

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Smoking Clouds Men's Minds (CME/CE)

MedPage Today Psychiatry — Mon, 06 Feb 2012 20:00:00 +0100

(MedPage Today) -- Middle-age men who smoke may be setting themselves up for rapid cognitive decline, researchers found. (Source: MedPage Today Psychiatry)

Genotype Distributions and Allele Frequencies of Possible Major Depressive Disorder-Associated Single Nucleotide Polymorphisms, Cyclic Adenosine Monophosphate Response Element Binding Protein 1 rs4675690 and Piccolo rs2522833, in a Japanese Population.

Biological and Pharmaceutical Bulletin — Mon, 06 Feb 2012 19:48:04 +0100

Authors: Inoue K, Ando N, Suzuki E, Hayashi H, Tsuji D, Itoh K Abstract It is known that the onset of major depressive disorder (MDD) would be associated with genetic factors. To investigate the susceptibility to psychiatric disorders, e.g. MDD, schizophrenia etc., it is necessary to compare the genetic differences of objective polymorphisms between in patients and in relative contol subjects. Recently, an increasing number of studies focused on the role of cyclic adenosine monophosphate response element binding protein 1 (CREB1) and Piccolo (PCLO) on MDD. However, there was no report about genetic characterization of polymorphisms in between MDD patients and healthy subjects in Japanese population. We analized genotype distributions and allele frequencies of CREB1 rs4675690 and PC...

Anxiety Therapy Doesn't Work as Well in ElderlyAnxiety Therapy Doesn't Work as Well in Elderly

Medscape Medical News Headlines — Mon, 06 Feb 2012 19:40:36 +0100

Cognitive behavioral therapy appears to help older adults battle anxiety disorders slightly better than other approaches, but not as well as in younger adults. Reuters Health Information (Source: Medscape Medical News Headlines)

"Malaria cure" claim sparks Vienna probe

Reuters: Health — Mon, 06 Feb 2012 18:08:28 +0100

VIENNA (Reuters) - A Vienna hospital is searching for long-retired staff who might hold clues to a man's claim that he was deliberately infected with malaria when he was a psychiatric patient nearly half a century ago. (Source: Reuters: Health)

College Degree Lowers Marriage Odds for Those From Disadvantaged Backgrounds

The Doctors Lounge - Psychiatry — Mon, 06 Feb 2012 18:00:00 +0100

Education can bridge the income gap, but not social or cultural differences, study says (Source: The Doctors Lounge - Psychiatry)

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Spanking Produces Troubled Kids, Study Contends

The Doctors Lounge - Psychiatry — Mon, 06 Feb 2012 18:00:00 +0100

Punishment linked to more aggression in children, two decades of research shows (Source: The Doctors Lounge - Psychiatry)

The Case for Retaining Bereavement Exclusion in DSM-5The Case for Retaining Bereavement Exclusion in DSM-5

Medscape Today Headlines — Mon, 06 Feb 2012 17:50:27 +0100

Two researchers argue that existing data do not support expanding the category of major depression by removing the bereavement exclusion. Medscape Medical News (Source: Medscape Today Headlines)

Am J Geriatr Psychiatry; +17 new citations

Am J Geriatr Psychia... — Mon, 06 Feb 2012 15:06:02 +0100

17 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Geriatr Psychiatry These pubmed results were generated on 2012/02/06PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resources. (Source: Am J Geriatr Psychia...)

Thousands of U.S. Kids Hospitalized for Abuse

The Doctors Lounge - Psychiatry — Mon, 06 Feb 2012 15:00:00 +0100

Infants, poor children most vulnerable, study suggests (Source: The Doctors Lounge - Psychiatry)

Parenting after Traumatic Events: Ways to Support Children

Psych Central — Mon, 06 Feb 2012 14:35:07 +0100

One of the most important messages for parents about traumatic experiences—such as car accidents, medical trauma, exposure to violence, disasters—that may impact them and their children is that while children of all ages can be impacted, most are resilient and able to cope and recover. Dr. Ann Masten from the University of Minnesota wrote in the journal American Psychologist (2001) about resilience as “ordinary magic.” That is, given normal protective factors, most children will be able to cope, recover, and be fine after witnessing or experiencing a traumatic event. Some children and adolescents may develop symptoms following a disaster, especially if they have experienced traumatic events earlier such as losses or other difficult situations. The symptoms related to trauma may ap...

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Magic mushrooms, international law and the failed 'war on drugs'

Guardian Unlimited Science — Mon, 06 Feb 2012 12:36:26 +0100

Recent research suggesting potential therapeutic benefits of psilocybin focus attention on the need to reform drug lawsIt's been a busy fortnight. First the publication of two major peer-reviewed research papers about magic mushrooms that attracted worldwide publicity. Then off to Prague for an international drugs policy symposium. And just last week, news of a large grant for our next collaborative study with Imperial College. But I'm getting ahead of myself.I established the Beckley Foundation some 14 years ago as a think tank on drugs policy. It was apparent even then that the "war on drugs" had failed. A 1997 report by the United Nations Drugs Control Programme put the value of the global trade in illicit drugs at around $400bn. Recent UN figures show that global production of opium (u...

Hospitalization for psychiatric disorders before and after onset of unprovoked seizures/epilepsy. - Adelöw C, Andersson T, Ahlbom A, Tomson T.

SafetyLit: All (Unduplicated) — Mon, 06 Feb 2012 11:54:53 +0100

OBJECTIVE:To study hospitalization for psychiatric disorders before and after onset of unprovoked epileptic seizures/epilepsy. METHOD:In this population-based case-control study, the cases were 1,885 persons from Stockholm with new onset of unprovoked seiz... (Source: SafetyLit: All (Unduplicated))

Expressed emotion and its relationship to anxiety and depression after traumatic brain injury. - Alway Y, McKay A, Ponsford J, Schönberger M.

SafetyLit: All (Unduplicated) — Mon, 06 Feb 2012 11:54:53 +0100

This study aimed to examine the relationship ... (Source: SafetyLit: All (Unduplicated))

The Factors Influencing Decision Making on Children's Psychiatric Hospitalization: A Retrospective Chart Review. - Golubchik P, Sever J, Finzi-Dottan R, Kosov I, Weizman A.

SafetyLit: All (Unduplicated) — Mon, 06 Feb 2012 11:54:53 +0100

Indications and criteria for psychiatric hospitalization (PH) continue to be questioned and assessed. We investigated the major clinical criteria affecting child psychiatrists' decision to recommend hospitalization. Records of 80 children (aged 7-13 years... (Source: SafetyLit: All (Unduplicated))

Memory And Silence - A Complex Relationship

Health News from Medical News Today — Mon, 06 Feb 2012 09:00:00 +0100

People who suffer a traumatic experience often don't talk about it, and many forget it over time. But not talking about something doesn't always mean you'll forget it; if you try to force yourself not to think about white bears, soon you'll be imagining polar bears doing the polka. A group of psychological scientists explore the relationship between silence and memories in a new paper published in Perspectives on Psychological Science, a journal of the Association for Psychological Science... (Source: Health News from Medical News Today)

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Psychedelic drugs: more a case of 'turn off, tune in, drop out' | Johnjoe McFadden

Guardian Unlimited Science — Mon, 06 Feb 2012 08:00:00 +0100

Magic mushrooms work by shutting down parts of the brain, not expanding the mind, according to new researchSix thousand years ago palaeolithic hunters painted images on the walls of the Selva Pascuala caves in Spain that look remarkably similar to locally abundant Psilocybe hispanica, one of the many "magic mushrooms" that contains the hallucinogen psilocybin. The same or similar mushrooms have been used throughout the ages to induce states of religious ecstasy, spiritual enlightenment, mystical meanderings or simply to have a great time. But how do they work? Timothy Leary, who famously told a generation of Americans to "turn on, tune in, drop out", claimed these "mind-expanding chemicals … acts as a chemical key – it opens the mind, frees the nervous system of its ordinary patterns a...

fluvoxamine, Luvox, Luvox CR

MedicineNet Depression General — Mon, 06 Feb 2012 07:00:00 +0100

Title: fluvoxamine, Luvox, Luvox CRCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 2/6/2012 (Source: MedicineNet Depression General)

Highly Sensitive to Noise?

About.com Bipolar Disorder — Mon, 06 Feb 2012 06:00:00 +0100

On our Main Forum, Drop-In Jane writes: "I was wondering, are any of you highly sensitive to noise? I'm moving, and part of the reason is that the walls here are ...Read Full Post (Source: About.com Bipolar Disorder)

Clinical differences between early‐ and late‐onset social anxiety disorders

Early Intervention in Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusion: Symptom severity and behavioural inhibitions, especially in social/school situations, were clinical characteristics that differentiated between early‐ and late‐onset SAD. (Source: Early Intervention in Psychiatry)

What Is Schizoaffective Disorder?

About.com Bipolar Disorder — Mon, 06 Feb 2012 05:00:00 +0100

Schizoaffective disorder is one of the least understood mental illnesses. Authorities differ on the description of the illness, and to make matters worse, the European and American definitions are quite a bit different. In the US, patients with schizoaffective disorder have symptoms of both schizophrenia and bipolar disorder - but there is a lot more to it. Misdiagnosis is common, but fortunately, even when the condition isn't properly diagnosed, treatment may still be effective. Read the best available information, what the problems in diagnosis are, and why treatment doesn't depend on the right diagnosis: What Is Schizoaffective Disorder?.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Learn more or join the conversation! NEWSLETTER | FORUM | ...

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Mental Health Weekly — Mon, 06 Feb 2012 05:00:00 +0100

AbstractColorado Promoting Efficient BH Care Delivery Through Telehealth ProgramTechnology, Work of Change Teams Enhance Access at Kentucky CenterEmployment Program Positive for Veterans With PTSDHouse Votes to Repeal Long‐Term Care Insurance ProgramGroups Prepare to File Brief to Support ACA Medicaid ExpansionBriefly NotedState NewsBusinessComing up (Source: Mental Health Weekly)

Does Abortion in First Trimester Raise Risk of Mental Ills’ Return?

The Doctors Lounge - Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Danish study found women who gave birth were more likely to be readmitted in the month afterwards (Source: The Doctors Lounge - Psychiatry)

Error in Text in: Chauvet Cave: The Panel of Horses [Correction]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

(Source: Archives of General Psychiatry)

Brain Anatomy and Its Relationship to Behavior in Adults With Autism Spectrum Disorder: A Multicenter Magnetic Resonance Imaging Study [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Adults with ASD have distributed differences in brain anatomy and connectivity that are associated with specific autistic features and traits. These results are compatible with the concept of autism as a syndrome characterized by atypical neural "connectivity." (Source: Archives of General Psychiatry)

Assessment of Pedophilia Using Hemodynamic Brain Response to Sexual Stimuli [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Functional brain response patterns to sexual stimuli contain sufficient information to identify pedophiles with high accuracy. The automatic classification of these patterns is a promising objective tool to clinically diagnose pedophilia. (Source: Archives of General Psychiatry)

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Altered Neural Reward Representations in Pathological Gamblers Revealed by Delay and Probability Discounting [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions The results extend previous reports of a generally hypoactive reward system in pathological gamblers by showing that, even when subjective reward valuation is accounted for, gamblers still show altered reward representations. Furthermore, results point toward a gradual degradation of mesolimbic reward representations for delayed rewards during the course of pathological gambling. (Source: Archives of General Psychiatry)

Prevention of Posttraumatic Stress Disorder by Early Treatment: Results From the Jerusalem Trauma Outreach and Prevention Study [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Prolonged exposure, CT, and delayed PE effectively prevent chronic PTSD in recent survivors. The lack of improvement from treatment with escitalopram requires further evaluation. Trauma-focused clinical interventions have no added benefit to survivors with subthreshold PTSD symptoms. Trial Registration clinicaltrials.gov Identifier: NCT00146900 (Source: Archives of General Psychiatry)

First-Time First-Trimester Induced Abortion and Risk of Readmission to a Psychiatric Hospital in Women With a History of Treated Mental Disorder [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Risk of readmission is similar before and after first-time first-trimester abortion, contrasting with a marked increased in risk of readmission post partum. We speculate that recent psychiatric episodes may influence women's decisions to have an induced abortion; however, this decision does not appear to influence the illness course in women with a history of treated mental disorders. (Source: Archives of General Psychiatry)

Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions The findings of this study support the long-term safety and antidepressant efficacy of subcallosal cingulate DBS for TRD and suggest equivalent safety and efficacy for TRD in patients with BP. Trial Registration clinicaltrials.gov Identifier: NCT00367003 (Source: Archives of General Psychiatry)

Anterior Cingulate Cortex {gamma}-Aminobutyric Acid in Depressed Adolescents: Relationship to Anhedonia [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions These findings suggest that GABA, the major inhibitory neurotransmitter in the brain, may be implicated in adolescent MDD and, more specifically, in those with anhedonia. In addition, use of a continuous rather than categorical scale of anhedonia, as in the present study, may permit greater specificity in evaluating this important clinical feature. (Source: Archives of General Psychiatry)

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Negative Symptoms and the Failure to Represent the Expected Reward Value of Actions: Behavioral and Computational Modeling Evidence [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Negative symptoms in schizophrenia are associated with a specific reinforcement learning abnormality: patients with high-negative symptoms do not represent the expected value of rewards when making decisions but learn to avoid punishments through the use of prediction errors. This computational framework offers the potential to understand negative symptoms at a mechanistic level. (Source: Archives of General Psychiatry)

Randomized Trial to Evaluate the Efficacy of Cognitive Therapy for Low-Functioning Patients With Schizophrenia [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusion Cognitive therapy can be successful in promoting clinically meaningful improvements in functional outcome, motivation, and positive symptoms in low-functioning patients with significant cognitive impairment. Trial Registration clinicaltrials.gov Identifier: NCT00350883 (Source: Archives of General Psychiatry)

Cognitive Therapy for Negative Symptoms of Schizophrenia [Editorial]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

(Source: Archives of General Psychiatry)

Washington Crossing the Delaware [Art and Images in Psychiatry]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

(Source: Archives of General Psychiatry)

This Month in Archives of General Psychiatry [This Month in Archives of General Psychiatry]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

(Source: Archives of General Psychiatry)

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About This Journal [About This Journal]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

(Source: Archives of General Psychiatry)

Differences in the Circuitry-Based Association of Copy Numbers and Gene Expression Between the Hippocampi of Patients With Schizophrenia and the Hippocampi of Patients With Bipolar Disorder [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusion Insertions and deletions of genomic DNA in -aminobutyric acid cells at a key locus of the hippocampal circuit are reflected in transcriptional changes in GAD67 regulation that are circuitry-based and diagnosis-specific. (Source: Archives of General Psychiatry)

Impact of Smoking on Cognitive Decline in Early Old Age: The Whitehall II Cohort Study [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Compared with never smokers, middle-aged male smokers experienced faster cognitive decline in global cognition and executive function. In ex-smokers with at least a 10-year cessation, there were no adverse effects on cognitive decline. (Source: Archives of General Psychiatry)

Influence of Patient Race and Ethnicity on Clinical Assessment in Patients With Affective Disorders [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions African American individuals exhibited significantly higher rates of clinical diagnoses of schizophrenia than non-Latino white subjects, even after controlling for covariates such as serious affective disorder. (Source: Archives of General Psychiatry)

Suicidal Thoughts and Behavior With Antidepressant Treatment: Reanalysis of the Randomized Placebo-Controlled Studies of Fluoxetine and Venlafaxine [Meta-analysis]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Fluoxetine and venlafaxine decreased suicidal thoughts and behavior for adult and geriatric patients. This protective effect is mediated by decreases in depressive symptoms with treatment. For youths, no significant effects of treatment on suicidal thoughts and behavior were found, although depression responded to treatment. No evidence of increased suicide risk was observed in youths receiving active medication. To our knowledge, this is the first research synthesis of suicidal thoughts and behavior in depressed patients treated with antidepressants that examined the mediating role of depressive symptoms using complete longitudinal person-level data from a large set of published and unpublished studies. (Source: Archives of General Psychiatry)

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Self-Diagnosing Your Marriage Problems? Beware!

Psychology Today Anxiety Center — Mon, 06 Feb 2012 00:26:35 +0100

Eric Clapton's famed song suggests "Before you accuse me, take a look at yourself." If you are going to try to understand and fix problems that come up in your marriage, sit down and look inward instead of pointing fingers at your spouse's errors.read more (Source: Psychology Today Anxiety Center)

What Are the Major Diseases Involving Copper Metabolism?

PediatricEducation.org — Mon, 06 Feb 2012 00:08:49 +0100

Discussion Nutritional problems can occur in all parts of the world and in all socioeconomic strata. Caloric and/or protein inadequacy unfortunately plagues too many people because of inadequate supplies or availability. Supplemental food programs around the world attempt to provide appropriate nutrition, but can be stymied because of war, political instability, economic instability and many other social factors. The most common specific nutrient deficiencies are iron and Vitamin D deficiencies. Minerals important for essential nutrition include copper, iodine, selenium and zinc. A typical mixed diet usually provides enough minerals. In the United States, mineral deficiencies are usually uncommon unless there is an underlying disease process or abnormal food restrictions or diet. Vegan an...

Social Support Is Critical for Depression Recovery

Psych Central — Sun, 05 Feb 2012 20:38:51 +0100

Every human being wants to belong. This need is so strong that people will do nearly anything to feel like they are part of something. Personal relationships form a safety net around individuals to protect them from too much isolation. Long ago, people who strayed from a group had a much harder time surviving the elements or avoiding starvation. While it’s physically safer now to live a solitary life, emotional isolation can still threaten a person’s mental well-being. Social support is a vital and effective part of depression recovery. It can turn around damaging isolation, affect a person’s life focus, and generate solutions for depression management. Learn more about how this powerful social force can positively effect someone living with depression. Social Connection Curbs You...

Even pediatricians want suicide warning placed on ADHD drugs

NaturalNews.com — Sun, 05 Feb 2012 06:00:00 +0100

Both ADHD's diagnosis and treatment with mild altering psychiatric drugs have been frequently contested topics. Much of the vague criteria for diagnosis is highly subjective, as many of the symptoms associated with the "disorder" are obvious consequences of forcing young... (Source: NaturalNews.com)

Distress, defiance or adaptation? A review paper of at‐risk mental health states in young offenders

Early Intervention in Psychiatry — Sun, 05 Feb 2012 05:00:00 +0100

Conclusion: The main conclusion is that this population have many risk factors which increase the possibility of developing serious mental health problems, therefore highlighting the need for early intervention. (Source: Early Intervention in Psychiatry)

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Increased medial orbitofrontal [18F]fluorodopa uptake in Parkinsonian impulse control disorders

Movement Disorders — Sun, 05 Feb 2012 05:00:00 +0100

Conclusions:Increased monoaminergic activity in the medial orbitofrontal cortex might be associated with increased sensitivity for ICDs under dopamine‐replacement therapy in PD. © 2012 Movement Disorder Society (Source: Movement Disorders)

The prevalence of children affected by parental cancer and their use of specialised psychiatric services: The 1987 finnish birth cohort study

International Journal of Cancer — Sun, 05 Feb 2012 05:00:00 +0100

This study examined the prevalence of children affected by parental cancer at national level and whether these children use specialised psychiatric services more than their peers. The study is a retrospective population‐based registry study. All 60,069 children born in Finland in 1987 were followed up with various health and social registers from 1987 to 2008. The associations of parental cancer treatments with children's psychiatric service use were analysed with logistic regressions. During the 21‐year follow‐up 3,909 (6.6%) of the children had a parent suffering from cancer. The children of the cancer patients used more specialised psychiatric care than their peers and the service use depended on parent's gender, as well as cohort members' gender and the age at occurrence. The com...

Test–retest reliability of the Xhosa version of the Diagnostic Interview Schedule for Children

Child: Care, Health and Development — Sat, 04 Feb 2012 23:54:28 +0100

Conclusion The results of this study suggest that the test–retest reliability of the Xhosa version of the DISC‐IV is similar to the reliability reported in other translated versions of the instrument. The satisfactory reliability and straightforward application make this instrument suitable for use in South Africa. (Source: Child: Care, Health and Development)

Science News » Gene Regulator in Brain’s Executive Hub Tracked Across Lifespan – NIH study

National Institute of Mental Health — Sat, 04 Feb 2012 14:45:47 +0100

For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain’s executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia and autism turn out to be members of a select club of genes in which regulatory activity peaks during an environmentally-sensitive critical period in development. (Source: National Institute of Mental Health)

Anxiety UK is seeking a Peer M…

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

Anxiety UK is seeking a Peer Mentoring Project Coordinator. To find out more & apply, visit http://t.co/PLJnswV4 (Source: ANXIETY UK News)

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Anxiety UK is seeking a Peer Mentoring Project Coordinator

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

Anxiety UK is seeking a Coordinator to lead on the charity’s successful Peer Mentoring Project. Funded by Big Lottery, the project supports peer mentors and mentees in their journey back into employment, training or further volunteering. To find out more about the vacancy and to apply, click here. Closing date for applications is 12:00 pm on [...] (Source: ANXIETY UK News)

A failure to treat people with…

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

A failure to treat people with mental health problems & help them back into work costs society £67bn annually, says New Philanthropy Capital (Source: ANXIETY UK News)

Mental illness receives only 6…

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

Mental illness receives only 6.5% of total health spending & will soon be biggest burden on society, says Andy Burnham. http://t.co/ySFR8jcc (Source: ANXIETY UK News)

Hooray! More than 6,000 people…

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

Hooray! More than 6,000 people have downloaded our Smartphone App, Stress Tips. It’s free to download via http://t.co/C5WSqXgB. (Source: ANXIETY UK News)

Visit http://t.co/DhONeR3W to …

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

Visit http://t.co/DhONeR3W to see Ursula James’ appearance on @thismorning Tuesday , talking about emetophobia. (Source: ANXIETY UK News)

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What did you think about our helpline?

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

Anxiety UK has agreed to take part in an external evaluation which is being carried out by the Mental Health Foundation, an independent UK charity. The purpose of the evaluation is to see whether our helpline service is useful to you, and also how we could improve our services. What is your experience of using [...] (Source: ANXIETY UK News)

What is your experience of usi…

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

What is your experience of using our helpline? We’d love to hear about it. Please complete this online survey by 26/2 http://t.co/Jl4JnoKj (Source: ANXIETY UK News)

Data from 50s shows we worked …

ANXIETY UK News — Sat, 04 Feb 2012 14:45:45 +0100

Data from 50s shows we worked longer hours & took fewer holidays, yet anxiety in the workplace has risen in that time. http://t.co/jM1u8Wtr (Source: ANXIETY UK News)

Chinese version of MDQ effective for BD screening

MedWire News - Psychiatry — Sat, 04 Feb 2012 14:44:52 +0100

The failure of perivascular drainage of amyloid beta and pathogenesis of Alzheimer's Disease (2012-02-14)

Institute of Psychiatry | Events — Sat, 04 Feb 2012 14:42:27 +0100

Proteomics Interest Group at the Institute of Psychiatry Title: “The failure of perivascular drainage of amyloid beta and pathogenesis of Alzheimer’s Disease” Speaker: Dr Roxana Carare MD PhD Seminar Room 3, Institute of Psychiatry, Denmark Hill Campus Tuesday 14th February, 12:00-13:00Hrs<br style="mso-special-character:&am (Source: Institute of Psychiatry | Events)

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Journal Club and Grand Round (2012-02-08)

Institute of Psychiatry | Events — Sat, 04 Feb 2012 14:42:27 +0100

<h3 dir="ltr" align="left:: <span class="Apple-style-span&qu (Source: Institute of Psychiatry | Events)

Dynamic Genetics and the SGDP spACE Program (2012-02-08)

Institute of Psychiatry | Events — Sat, 04 Feb 2012 14:42:27 +0100

Recent large-scale genome-wide association studies have been successful in identifying some of the genetic variants associated with complex human disorders. We often assume these associations will hold true within the same population irrespective of age or environmental context. However, twin and family studies tell us that for some traits heritability increases throughout childhood and adolescen (Source: Institute of Psychiatry | Events)

Erratum

Journal of Child Psychology and Psychiatry — Sat, 04 Feb 2012 14:41:12 +0100

(Source: Journal of Child Psychology and Psychiatry)

Editorial: Can we dissect the interplay of genes and environment across development?

Journal of Child Psychology and Psychiatry — Sat, 04 Feb 2012 14:40:51 +0100

(Source: Journal of Child Psychology and Psychiatry)

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Whatever Happened to Speculative Thought? Some Historical Evidence Against Evidence-Based Medicine

Psychiatric Times — Sat, 04 Feb 2012 14:30:01 +0100

Any physician can predict death as the outcome of a fatal illness, but the physician who can predict death from among seeming randomness has certainly acquired a superior level of insight. (Source: Psychiatric Times)

Sleep Troubles May Up Prostate Cancer Risk

MedPage Today Psychiatry — Sat, 04 Feb 2012 13:13:09 +0100

SAN FRANCISCO (MedPage Today) -- Severe sleep problems suggestive of insomnia are associated with an increased risk of prostate cancer among older men, researchers found. (Source: MedPage Today Psychiatry)

Brain Injury Rate 7 Times Greater among U.S. Prisoners

Scientific American - Official RSS Feed — Sat, 04 Feb 2012 13:00:00 +0100

A car accident, a rough tackle, an unexpected tumble. The number of ways to bang up the brain are almost as numerous as the people who sustain these injuries. And only recently has it become clear just how damaging a seemingly minor knock can be. Traumatic brain injury (TBI) is no longer just a condition acknowledged in military personnel or football players and other professional athletes. Each year some 1.7 million civilians will suffer an injury that disrupts the function of their brains, qualifying it as a TBI. [More] (Source: Scientific American - Official RSS Feed)

Genetic Connection To Traumatic Experience

Health News from Medical News Today — Sat, 04 Feb 2012 08:00:00 +0100

Rutgers scientists have uncovered genetic clues as to why some mice no longer in danger are still fearful while others are resilient to traumatic experiences - knowledge that could help those suffering with crippling anxiety and PTSD. "Our work with mice demonstrates how genes play a role in developing and extinguishing pathological fear like Post Traumatic Stress Disorder," says Gleb Shumyatsky, an associate professor in the Department of Genetics in the School of Arts and Sciences... (Source: Health News from Medical News Today)

All bath salts are not mephedrone

The Poison Review — Sat, 04 Feb 2012 05:56:41 +0100

2.5 out of 5 stars “Bath Salt” Ingestion Leading to Severe Intoxication Delirium: Two Cases and a Brief Review of the Emergence of Mephedrone Use. Kasick DP et al. Am J Drug Alcohol Abuse 2012 Jan 5 [Epub ahead of print] Abstract This paper from the Ohio State Department of Psychiatry is worth reading for vivid descriptions of acute toxic delirium in two patients after they used a product sold as “bath salts”: Patient A presented after ingesting “bath salts” sold under the label “Arctic Blast”. He was tachycardic (heart rate = 144.min), anxious and paranoid, and suffering visual hallucinations of snakes. For some bizarre reason he was given 2 mg naloxone in the field. At the hospital, he slowly improved after treatment with fluids, lorazep...

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What Are the Causes of Bipolar Disorder?

About.com Bipolar Disorder — Sat, 04 Feb 2012 05:00:00 +0100

In Part 2 of Bipolar for Beginners, we take a look at what scientists believe are the causes - genetic, physical and psychological - of bipolar disorder. For whatever reason you want to know more about this illness, here is information in clear English that will answer some of your questions about things like whether bipolar is inherited, the part brain chemistry plays in bipolar, and how researchers believe it all fits together. (Source: About.com Bipolar Disorder)

DIY science: should you try this at home?

Guardian Unlimited Science — Fri, 03 Feb 2012 22:59:00 +0100

When Richard Handl was arrested for attempting to split the atom on his stove, he joined a growing band of home experimenters cooking up all kinds of trouble behind the kitchen doorÄngelholm is a pretty southern Swedish town, famed for its clay cuckoo manufacturing, a clay cuckoo being a kind of ocarina, which is a kind of flute. The crime rate here is practically zero. Except one of its residents was last year arrested for trying to split the atom in his kitchen. His name is Richard Handl and he buzzes me into his first-floor flat.I wanted to meet Richard because I keep seeing reports of home science experimenters clashing with the authorities. There's been a spate of them this past year or two.I glance into Richard's kitchen and recognise his cooker from the news. It was horrendously, a...

What’s My Zip Code?

Psych Central — Fri, 03 Feb 2012 19:31:54 +0100

When I first saw this book “What’s My Zip Code?” by David Stringer, it was in download format and I wondered what exactly it would be about because it seemed like an odd title to me. After reading the book I feel as though the title is very fitting. I’ve now seen the cover and how telling even that is! The picture of a forlorn young man standing at a rundown “campsite” is exactly as the reader will feel about the main character. David Stringer has a well-written account of how a family member can feel about their mentally ill, substance-abusing sibling and son. In his first-person memoir the reader can’t help but empathize with David and his family but also feel strong emotions for David’s brother John who is riddled with problems. ...

Who Is Left Out of the DSM-5 Debate? Of Course, Consumers

Psychology Today Parenting Center — Fri, 03 Feb 2012 17:50:12 +0100

To my ears, the current DSM-5 debate comes down to the question of who has the right to decide when an individual and a family have suffered enoughread more (Source: Psychology Today Parenting Center)

Obesity, Mental Illness 'Dangerously Linked'Obesity, Mental Illness 'Dangerously Linked'

Medscape Today Headlines — Fri, 03 Feb 2012 17:19:00 +0100

The complex link between obesity and mental illness involves several driving factors, all of which should be considered when choosing effective interventions, researchers say. Medscape Medical News (Source: Medscape Today Headlines)

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Genetic Variation in the Epigenetic Machinery and Mental Health

Current Psychiatry Reports — Fri, 03 Feb 2012 17:11:15 +0100

Abstract DNA methylation and chromatin modifications regulate gene expression and contribute to changes in brain transcriptomes underlying neurodevelopmental and psychiatric disorders. Clinical genetics and preclinical animal models highlight the crucial importance of the correct establishment of epigenetic marks during sensitive windows of development for normal brain function. On the same side of the coin, some of the concerned factors also appear engaged in the programming of experience-dependent long-term effects on mental health following exposure to relevant early-life events. Delineating the particular role of genetic variations in these players could provide new insights into the molecular basis of vulnerability and resilience and advance tailored therapies. C...

Treatment Options for Tauopathies

Current Treatment Options in Neurology — Fri, 03 Feb 2012 17:11:02 +0100

Opinion statement To date, there are no approved and established pharmacologic treatment options for tauopathies, a very heterogenous group of neuropsychiatric diseases often leading to dementia and clinically diagnosed as atypical Parkinson syndromes. Among these so-called Parkinson plus syndromes are progressive supranuclear palsy (PSP), also referred to as Steele-Richardson-Olszewski syndrome; frontotemporal dementia (FTD); and corticobasal degeneration (CBD). Available treatment strategies are based mainly on small clinical trials, miscellaneous case reports, or small case-controlled studies. The results of these studies and conclusions about the efficacy of the medication used are often contradictory. Approved therapeutic agents for Alzheimer´s dementia, such as acet...

'Deep Mistrust' of Psychoactive Meds' Efficacy Unfounded'Deep Mistrust' of Psychoactive Meds' Efficacy Unfounded

Medscape Today Headlines — Fri, 03 Feb 2012 16:15:10 +0100

Drugs used to treat psychiatric illnesses are just as effective as those used to treat common medical illnesses, according to a new meta-analysis. Medscape Medical News (Source: Medscape Today Headlines)

The Science of Concussion and Brain Injury

Scientific American - Official RSS Feed — Fri, 03 Feb 2012 16:00:00 +0100

How medicine, sports and society are trying to heal and protect the brains of millions amidst the growing awareness of the long-lasting effects of traumatic head injury [More] (Source: Scientific American - Official RSS Feed)

Questionnaire Could Help Predict Alzheimer’s: Study

The Doctors Lounge - Psychiatry — Fri, 03 Feb 2012 15:00:00 +0100

21 simple questions may help docs determine which patients need more testing, researchers say (Source: The Doctors Lounge - Psychiatry)

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Could a Blood Test Help Spot Depression?

The Doctors Lounge - Psychiatry — Fri, 03 Feb 2012 15:00:00 +0100

Small study suggests 'biomarker' levels might help support a diagnosis, but more research needed (Source: The Doctors Lounge - Psychiatry)

Measures Must Be Taken To Prevent Depression In Adolescents

Health News from Medical News Today — Fri, 03 Feb 2012 15:00:00 +0100

As one of the most common, unrecognized and untreated health problems among young people, tackling depression is a serious priority for countries worldwide. The psychiatric disorder causes serious social and educational problems for patients, as well as leading to increased risk of suicide and substance abuse. A review of a published article in The Lancet urges that more measures are needed to prevent depression in non-specialist settings, such as schools and communities... (Source: Health News from Medical News Today)

What Real Commitment To Your Marriage Means

Health News from Medical News Today — Fri, 03 Feb 2012 09:00:00 +0100

What does being committed to your marriage really mean? UCLA psychologists answer this question in a new study based on their analysis of 172 married couples over the first 11 years of marriage. "When people say, 'I'm committed to my relationship,' they can mean two things," said study co-author Benjamin Karney, a professor of psychology and co-director of the Relationship Institute at UCLA. "One thing they can mean is, 'I really like this relationship and want it to continue.' However, commitment is more than just that... (Source: Health News from Medical News Today)

For Those With Low Self-Esteem, Facebook Is Not Such A Good Thing

Health News from Medical News Today — Fri, 03 Feb 2012 09:00:00 +0100

In theory, the social networking website Facebook could be great for people with low self-esteem. Sharing is important for improving friendships. But in practice, people with low self-esteem seem to behave counterproductively, bombarding their friends with negative tidbits about their lives and making themselves less likeable, according to a new study which will be published in Psychological Science, a journal of the Association for Psychological Science... (Source: Health News from Medical News Today)

Depressed Patients Accurately Distinguished From Healthy Controls By Blood Test

Health News from Medical News Today — Fri, 03 Feb 2012 09:00:00 +0100

The initial assessment of a blood test to help diagnose major depressive disorder indicates it may become a useful clinical tool. In a paper published in the journal Molecular Psychiatry, a team including Massachusetts General Hospital (MGH) researchers reports that a test analyzing levels of nine biomarkers accurately distinguished patients diagnosed with depression from control participants without significant false-positive results... (Source: Health News from Medical News Today)

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Mentoring Helps Survivors Of Violence, Child Abuse

Health News from Medical News Today — Fri, 03 Feb 2012 09:00:00 +0100

Can mentoring relationships help female students who survive childhood abuse or domestic violence? Absolutely, according to new research from Concordia University, published in the Journal of College Student Development. "Studies have shown that childhood abuse unleashes a chain of negative emotions that can impact an individual's future, producing feelings of shame, isolation, self-loathing and educational underachievement," says first author Rosemary C. Reilly, an associate professor in the Concordia Department of Applied Human Sciences... (Source: Health News from Medical News Today)

People-Pleasers Feel Pressure To Eat When They Believe It Will Help Another Person Feel More Comfortable

Health News from Medical News Today — Fri, 03 Feb 2012 08:00:00 +0100

If you are a people-pleaser who strives to keep your social relationships smooth and comfortable, you might find yourself overeating in certain social situations like Super Bowl watch parties. A new study from Case Western Reserve University found that, hungry or not, some people eat in an attempt to keep others comfortable. "They don't want to rock the boat or upset the sense of social harmony," says Julie Exline, a Case Western Reserve psychologist and lead author of the study... (Source: Health News from Medical News Today)

Child psychiatry and the developmental perspective

European Child and Adolescent Psychiatry — Fri, 03 Feb 2012 07:21:27 +0100

Content Type Journal ArticleCategory EditorialPages 1-2DOI 10.1007/s00787-012-0251-3Authors Guilherme V. Polanczyk, Department of Psychiatry, University of São Paulo Medical School, National Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), Rua Dr. Ovídio Pires de Campos 785, São Paulo, SP 05403-010, Brazil Journal European Child & Adolescent PsychiatryOnline ISSN 1435-165XPrint ISSN 1018-8827 (Source: European Child and Adolescent Psychiatry)

Inappropriate Medication in Home Health Care

Journal of General Internal Medicine — Fri, 03 Feb 2012 07:20:48 +0100

Content Type Journal ArticleCategory LettersPages 1-1DOI 10.1007/s11606-012-1997-5Authors Yuhua Bao, Department of Public Health, Weill Cornell Medical College, 402 E. 67th St., New York, NY 10065, USAHuibo Shao, Department of Public Health, Weill Cornell Medical College, 402 E. 67th St., New York, NY 10065, USATara F. Bishop, Departments of Public Health and Medicine, Weill Cornell Medical College, New York, NY, USABruce R. Schackman, Department of Public Health, Weill Cornell Medical College, 402 E. 67th St., New York, NY 10065, USAMartha L. Bruce, Department of Psychiatry, Weill Cornell Medical College, White Plains, NY, USA Journal Journal of General Internal MedicineOnline ISSN 1525-1497Print ISSN 0884-8734 (Source: Journal of General Internal Medicine)

Effects of ecstasy/polydrug use on memory for associative information

Psychopharmacology — Fri, 03 Feb 2012 07:19:30 +0100

Conclusions Overall, the results suggest that long-term ecstasy exposure may induce a deficit in associative learning and this may be in part a consequence of users adopting a more liberal decision criterion value. Content Type Journal ArticleCategory Original InvestigationPages 1-13DOI 10.1007/s00213-012-2652-xAuthors Denis T. Gallagher, School of Psychology, University of Central Lancashire, Darwin Building, Preston, Lancashire PR1 2HE, UKJohn E. Fisk, School of Psychology, University of Central Lancashire, Darwin Building, Preston, Lancashire PR1 2HE, UKCatharine Montgomery, Liverpool John Moores University, Liverpool, L3 3AF UKJeannie Judge, School of Psychology, University of Central Lancashire, Darwin Building, Preston, Lancashire PR1 2HE, UKSarita J. Robinson,...

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Itch Intensity and Scratching Pleasure Vary at Different Body Sites

MedicineNet Depression General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Itch Intensity and Scratching Pleasure Vary at Different Body SitesCategory: Health NewsCreated: 2/3/2012 11:01:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Depression General)

Could a Blood Test Help Spot Depression?

MedicineNet Depression General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Could a Blood Test Help Spot Depression?Category: Health NewsCreated: 2/3/2012 10:05:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Depression General)

Some Stroke Survivors Can't Recognize Fear, Anger in Others

MedicineNet Depression General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Some Stroke Survivors Can't Recognize Fear, Anger in OthersCategory: Health NewsCreated: 2/2/2012 6:06:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Depression General)

Is It a Disorder?

Psychology Today — Fri, 03 Feb 2012 07:00:00 +0100

Drawing the line between quirkiness and illness. (Source: Psychology Today)

Hurry Up! Let's Talk About Anxiety!

Psychology Today Anxiety Center — Fri, 03 Feb 2012 06:32:23 +0100

It's a catch phrase, "I'm nervous". My seven year-old is anxious his basketball team might lose against the orange team this weekend. Anxiety and the anxious lexicon have crept into our society over the past decades and we as a culture have turned into a bundle of nervous. So many people are placed on anxiolytics like Xanax or Ativan; which is like getting a brand new car.&nbsread more (Source: Psychology Today Anxiety Center)

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Intersubunit Bridge Formation Governs Efficacy of {alpha}4{beta}2 Agonists [Molecular Biophysics]

Journal of Biological Chemistry — Fri, 03 Feb 2012 05:00:00 +0100

The α4β2 subtype of the nicotinic acetylcholine receptor has been pursued as a drug target for treatment of psychiatric and neurodegenerative disorders and smoking cessation aids for decades. Still, a thorough understanding of structure-function relationships of α4β2 agonists is lacking. Using binding experiments, electrophysiology and x-ray crystallography we have investigated a consecutive series of five prototypical pyridine-containing agonists derived from 1-(pyridin-3-yl)-1,4-diazepane. A correlation between binding affinities at α4β2 and the acetylcholine-binding protein from Lymnaea stagnalis (Ls-AChBP) confirms Ls-AChBP as structural surrogate for α4β2 receptors. Crystal structures of five agonists with efficacies at α4β2 from 21–76% were determined in complex with Ls-A...

Biased Analogs at Individual G Protein Family Subtypes [Membrane Biology]

Journal of Biological Chemistry — Fri, 03 Feb 2012 05:00:00 +0100

We used a bioluminescence resonance energy transfer biosensor to screen for functional selective ligands of the human oxytocin (OT) receptor. We demonstrated that OT promoted the direct engagement and activation of Gq and all the Gi/o subtypes at the OT receptor. Other peptidic analogues, chosen because of specific substitutions in key OT structural/functional residues, all showed biased activation of G protein subtypes. No ligand, except OT, activated GoA or GoB, and, with only one exception, all of the peptides that activated Gq also activated Gi2 and Gi3 but not Gi1, GoA, or GoB, indicating a strong bias toward these subunits. Two peptides (DNalOVT and atosiban) activated only Gi1 or Gi3, failed to recruit β-arrestins, and did not induce receptor internalization, providing the first cl...

Benefits and Mechanisms of Recovery Among Peer Providers With Psychiatric Illnesses

Qualitative Health Research — Fri, 03 Feb 2012 05:00:00 +0100

Providing peer support to individuals with psychiatric disabilities has emerged as a promising modality of mental health services. These services are delivered by individuals who experience mental illnesses themselves. The purpose of this study was to explore how working as a peer provider can enhance personal recovery. The study was conducted with 31 peer providers employed in a variety of mental health agencies. Data were collected through face-to-face semistructured interviews and analyzed using a grounded theory approach. Qualitative analysis revealed a wide range of recovery benefits for the peer providers. The benefits span across five wellness domains: foundational, emotional, spiritual, social, and occupational. In addition, analysis revealed five role-related and five work-environ...

[Original Articles] Altered Psychobiological Responsiveness in Women With Irritable Bowel Syndrome

Psychosomatic Medicine — Fri, 03 Feb 2012 05:00:00 +0100

Conclusions The enhanced morning cortisol levels in one subgroup of IBS patients may indicate an association between basal HPA axis activity and predominant bowel habit. The downregulated HPA axis reactivity in IBS after the TSST suggests a downregulated sensitivity of the endocrine system. On the contrary, all subjective stress ratings were increased in the IBS group, which may indicate increased stress susceptibility. (Source: Psychosomatic Medicine)

[Original Articles] Emotional Stress and Heart Rate Variability Measures Associated With Cardiovascular Risk in Relocated Katrina Survivors

Psychosomatic Medicine — Fri, 03 Feb 2012 05:00:00 +0100

Conclusions Results showed this multilayer trauma’s impact on emotional health and HRV-based measures of autonomic nervous system dysregulation. Specifically, dysregulation of depressed survivors’ HRV in response to trauma reminders supports more autonomic involvement in traumatic loss/depression than in PTSD. Diagnostic criteria for PTSD include physiologic reactivity, and the present findings suggest that, in this setting, altered physiologic reactivity observed when PTSD coexists with depression. (Source: Psychosomatic Medicine)

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Community-Based Case Management for the Prevention of Suicide Reattempts in Kaohsiung, Taiwan.

Community Mental Health Journal — Fri, 03 Feb 2012 05:00:00 +0100

Authors: Chen WJ, Chen CC, Ho CK, Lee MB, Lin GG, Chou FH Abstract Although a previous suicide attempt constitutes a major risk factor for an eventual completed suicide, few interventions specifically designed to prevent suicide reattempts have been evaluated. The aim of this study was to determine the effectiveness of case management for the prevention of suicide reattempts. A total of 4,765 subjects with a recent suicide attempt referred from medical and non-medical organizations were consecutively recruited from July 2006 to June 2008. The suicide prevention program of Kaohsiung Suicide Prevention Center (KSPC) provided case management and followed up suicide-attempt cases for 6 months. Survival analysis showed that the risk of suicide reattempt was significantly lower in the c...

The Alabama Coalition for a Healthier Black Belt: A Proof of Concept Project.

Community Mental Health Journal — Fri, 03 Feb 2012 05:00:00 +0100

Authors: Savage RM, Dillon JM, Hammel JC, Lewis TC, Johnson NC, Barlow LM, Brooms MM, Moore PM, Parker HE, Rodney KZ Abstract The Alabama Coalition for a Healthier Black was a demonstration of concept project. This paper is a descriptive and qualitative overview of this 2.5 year project. Limited key project results are reported here. Located in the rural Black Belt region of Alabama this coalition had several key aims: to develop a collaboration between primary care and mental health care through co-location of services; use of video-conferencing capability to provide mental health services more efficiently; enhanced training in rural healthcare; and development of stigma reduction campaigns along with other coalition partner specific initiatives. Co-location and telepsychiatry im...

Early Intervention Services for Psychosis and Time Until Application for Disability Income Support: A Survival Analysis.

Community Mental Health Journal — Fri, 03 Feb 2012 05:00:00 +0100

Authors: Krupa T, Oyewumi K, Archie S, Stuart Lawson J, Nandlal J, Conrad G Abstract Ensuring the financial security of individuals recovering from first episode psychosis is imperative, but disability income programs can be powerful disincentives to employment, compromising the social and occupational aspects of recovery. Survival analysis and Cox regression analysis were used to examine the rate at which individuals served by early intervention for psychosis (EIP) services apply for government disability income benefits and factors that predict rate of application. Health records for 558 individuals served by EIP programs were reviewed. Within the first year of receiving services 30% will make application for disability income; 60% will do so by 5 years. Rate of application is p...

Smaller Plate Won’t Help Your Diet, Research Shows

The Doctors Lounge - Psychiatry — Fri, 03 Feb 2012 05:00:00 +0100

People eat until full regardless of the dinnerware, researcher says (Source: The Doctors Lounge - Psychiatry)

MedWorm: Psychiatry

ISPNE Call for Abstracts

ISPNE Conference Announcement

2012 Curt P. Richter Award of the International Society of Psychoneuroendocrinology (ISPNE)

Erratum to “Acknowledgement to Reviewers” [Psychoneuroendocrinology 37 (2012) I–VI]

The steroid/peptide theory of social bonds: A reply to Goodson's Letter to the Editor

Nonapeptides are not just for bonding: A response to van Anders et al. (2011)

A sniff of trust: Meta-analysis of the effects of intranasal oxytocin administration on face recognition, trust to in-group, and trust to out-group

Regulation of corticoid and serotonin receptor brain system following early life exposure of glucocorticoids: Long term implications for the neurobiology of mood

Periodic maternal separation decreases hippocampal neurogenesis without affecting basal corticosterone during the stress hyporesponsive period, but alters HPA axis and coping behavior in adulthood

Effects of testosterone on attention and memory for emotional stimuli in male rhesus monkeys

Mouse females devoid of exposure to males during fetal development exhibit increased maternal behavior

Interactive effects of estrogen and serotonin on brain activation during working memory and affective processing in menopausal women

Cerebrospinal fluid cortisol concentrations in healthy elderly are affected by both APOE and TOMM40 variants

AMPK γ2 subunit gene PRKAG2 polymorphism associated with cognitive impairment as well as diabetes in old age

Neuroendocrine response to CRF stimulation in veterans with and without PTSD in consideration of war zone era

Ageing, physical function, and the diurnal rhythms of cortisol and dehydroepiandrosterone

Symptom-specific associations between low cortisol responses and functional somatic symptoms: The TRAILS study

Adulthood trauma and HPA-axis functioning in healthy subjects and PTSD patients: A meta-analysis

Acute and chronic stress induced changes in sensitivity of peripheral inflammatory pathways to the signals of multiple stress systems – 2011 Curt Richter Award Winner

Editorial Board

Anxiety UK is seeking a Peer M…

Depression symptoms common in schizophrenia patients

Temperaments linked to clinical features and course in bipolar I disorder

Chinese version of MDQ effective for BD screening

Manuscript Submission Form

Guide for Authors

Table of Contents

Subscribers Page

Editorial Board

Genomic Tics in Tourette Syndrome

A brief summary of the articles appearing in this issue of Biological Psychiatry

Parental depressive symptoms and children’s sleep: the role of family conflict

The Invisible Disease Depression

Exercise Can Help Depression in Those With Chronic Illness

Drug Development in Pediatric Psychiatry: Current Status, Future Trends

The acute effects of kava and oxazepam on anxiety, mood, neurocognition; and genetic correlates: a randomized, placebo‐controlled, double‐blind study

The game's afoot: seeking viruses that cause chronic and degenerative neurologic and psychiatric disorder

Concordance between psychotropic prescribing for Veterans with PTSD and clinical practice guidelines

Customized adherence enhancement for individuals with bipolar disorder receiving antipsychotic therapy

Smoking Speeds Up Male Cognitive Decline

Free Depression Screening

General visual processing deficits may underlie social difficulties in schizophrenia

Antidepressants May Not Raise Suicide Risk in Youth: Study

Impaired memory following repeated pentylenetetrazol treatments in kindled mice.

The Gentle Self: How to Overcome Your Difficulties with Depression, Anxiety, Shyness, and Low Self-Esteem

Psych Signs Common in Kids With HIV (CME/CE)

Smoking Clouds Men's Minds (CME/CE)

Genotype Distributions and Allele Frequencies of Possible Major Depressive Disorder-Associated Single Nucleotide Polymorphisms, Cyclic Adenosine Monophosphate Response Element Binding Protein 1 rs4675690 and Piccolo rs2522833, in a Japanese Population.

Anxiety Therapy Doesn't Work as Well in ElderlyAnxiety Therapy Doesn't Work as Well in Elderly

"Malaria cure" claim sparks Vienna probe

College Degree Lowers Marriage Odds for Those From Disadvantaged Backgrounds

Spanking Produces Troubled Kids, Study Contends

The Case for Retaining Bereavement Exclusion in DSM-5The Case for Retaining Bereavement Exclusion in DSM-5

Am J Geriatr Psychiatry; +17 new citations

Thousands of U.S. Kids Hospitalized for Abuse

Parenting after Traumatic Events: Ways to Support Children

Magic mushrooms, international law and the failed 'war on drugs'

Hospitalization for psychiatric disorders before and after onset of unprovoked seizures/epilepsy. - Adelöw C, Andersson T, Ahlbom A, Tomson T.

Expressed emotion and its relationship to anxiety and depression after traumatic brain injury. - Alway Y, McKay A, Ponsford J, Schönberger M.

The Factors Influencing Decision Making on Children's Psychiatric Hospitalization: A Retrospective Chart Review. - Golubchik P, Sever J, Finzi-Dottan R, Kosov I, Weizman A.

Memory And Silence - A Complex Relationship

Psychedelic drugs: more a case of 'turn off, tune in, drop out' | Johnjoe McFadden

fluvoxamine, Luvox, Luvox CR

Highly Sensitive to Noise?

Clinical differences between early‐ and late‐onset social anxiety disorders

What Is Schizoaffective Disorder?

Table of Contents

Does Abortion in First Trimester Raise Risk of Mental Ills’ Return?

Error in Text in: Chauvet Cave: The Panel of Horses [Correction]

Brain Anatomy and Its Relationship to Behavior in Adults With Autism Spectrum Disorder: A Multicenter Magnetic Resonance Imaging Study [Original Article]

Assessment of Pedophilia Using Hemodynamic Brain Response to Sexual Stimuli [Original Article]

Altered Neural Reward Representations in Pathological Gamblers Revealed by Delay and Probability Discounting [Original Article]

Prevention of Posttraumatic Stress Disorder by Early Treatment: Results From the Jerusalem Trauma Outreach and Prevention Study [Original Article]

First-Time First-Trimester Induced Abortion and Risk of Readmission to a Psychiatric Hospital in Women With a History of Treated Mental Disorder [Original Article]

Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression [Original Article]

Anterior Cingulate Cortex {gamma}-Aminobutyric Acid in Depressed Adolescents: Relationship to Anhedonia [Original Article]

Negative Symptoms and the Failure to Represent the Expected Reward Value of Actions: Behavioral and Computational Modeling Evidence [Original Article]

Randomized Trial to Evaluate the Efficacy of Cognitive Therapy for Low-Functioning Patients With Schizophrenia [Original Article]

Cognitive Therapy for Negative Symptoms of Schizophrenia [Editorial]