MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with '454'. Sat, 03 Sep 2011 02:38:16 +0100 http://www.medworm.com/index.php?rid=5029208&cid=t_136511_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FxS7A0T_xTzA%2F Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us and we’ll share with it others. That’s right. Send us your announcements and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going, especially with all the layoffs. Despite the downsizing, there is movement. Here are some of the latest changes. Recognize anyone? And here is our regular feature. Send us a photo and we will spotlight a different person each week. This time around, we note that Sangamo BioSciences hired Geoffrey Nichol as executive vp for research and development. From 2002 to 2010, he was senior vp of product development at Medarex, which is now part of Bristol-Myers Squibb, and before that, he held various senior ma... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=5029208 Fri, 15 Jul 2011 12:53:56 +0100 5029208 http://www.medworm.com/index.php?rid=3453446&cid=t_136511_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FdgubNvhu0Tg%2F The contamination of the rotavirus vaccine Rotarix with porcine circovirus 1 DNA was revealed by deep sequencing. The same technique was also used to demonstrate that oral poliovirus vaccine does not contain viruses that can cause poliomyelitis. The oral poliovirus vaccine strains developed by Albert Sabin (pictured) were licensed in the United States in 1962, and over the next 37 years immunization with these vaccines lead to the eradication of poliomyelitis in this country. During that period, the vaccine was responsible for 5-10 cases of poliomyelitis each year, either in recipients of the vaccine or in their contacts. Some of these individuals have sued the manufacturers of the vaccine, claiming that they made a defective product. OPV contains three different poliovirus strains which w... virology blog blogs http://www.medworm.com/rss/comments.php?id=3453446 Thu, 08 Apr 2010 20:51:45 +0100 3453446 http://www.medworm.com/index.php?rid=1258595&cid=t_136511_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F241437369%2F The genetic mutations in cancer cells may vary in every patient, a study found, suggesting that drugs will need to be tailored more finely to small groups, The Wall Street Journal reports. The small study, by doctors at the Brigham and Women’s Hospital in Boston and scientists from a gene-reading unit of Roche Holding AG, is among the first to look comprehensively at the genes in cancerous tumors to find which genes went awry. The docs examined four patients with a rare and deadly lung-sac cancer called pleural mesothelioma, which strikes about 3,000 people a year. Every patient’s tumor had a different group of mutated genes, and no gene was mutated in more than one patient. That could explain why chemotherapy drugs work well in some patients and not at all in others, but it a... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1258595 Tue, 26 Feb 2008 11:35:34 +0100 1258595 http://www.medworm.com/index.php?rid=928808&cid=t_136511_131_f&fid=35005&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Ffungalcompgenomics%2F%7E3%2F165538880%2F Nature has an overview of what goes in and out of next generation sequencers with an interview with a smiling Chad Nusbaum from the Broad Institute. Most of these have been out and about for a while, but it seems that the hayride/bandwagon is starting to pick up more steam as GT's Genome Scan has several posts about sequencing referencing J. Craig V, George Church, and the Nature news article (not free). Note that Solexa is no longer the cool name - "Genome analyzer" being the name for the machine that was previously called Solexa 1G. I'm holding out hope for funnier names in the future. I do feel that ABI's choice of SOLiD is more exciting than 310/3700/3730 that is as inspiring as HAL9000. But I mean if your technology is called pyrosequencing, I am hoping Roche will come up with a firey... Fungal Genomes and Comparative Genomics blogs http://www.medworm.com/rss/comments.php?id=928808 Fri, 05 Oct 2007 04:42:56 +0100 928808 http://www.medworm.com/index.php?rid=918131&cid=t_136511_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F10%2Fwhat-f.html After reading Hsien's recent post, I am convinced how very much the UK needs a Sherpa. Listen to what is going on in Great Britain from Eye On DNA. "The UK Human Fertilisation and Embryology Authority has approved the use of preimplantation genetic diagnosis (PGD) to select embryos free of the gene for early-onset Alzheimer’s disease (AD). The couple who applied has a family history of the disease on the man’s side. His mother, grandmother, and two uncles all died from early-onset Alzheimer’s."Human Genetics Alert has been fighting the good Sherpa fight for years. The problem....the UK is still approving these techniques. I hate to tell all of you, but this is what is coming. Why scan a genome? Why do lightspeed sequencing when you have time to wait? Why? The answer is simple. To rap... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=918131 Mon, 01 Oct 2007 23:09:00 +0100 918131 http://www.medworm.com/index.php?rid=811311&cid=t_136511_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F08%2Fvineyards-and-longevity.html A friend of mine told me that she was on a wine tour and went to a Vineyard called Chamard. While there she was given a brochure.....The brochure contained information regarding the Methusaleh Project. It turns out that the vineyard was recently bought by Dr Rothberg. I found this an interesting place to recruit for the study. True, the elderly have imbibed, and those visiting vineyards often are retired. So perhaps this is an adequate place for sampling.I just wanted to mention the Methusaleh project again. Personally I think this is an intriguing idea. I have examined Nir Barzilai's project as well. Imagine...go to a vineyard, get a cheek swab. (Source: Gene Sherpas: Personalized Medicine and You) Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=811311 Mon, 20 Aug 2007 18:03:00 +0100 811311 http://www.medworm.com/index.php?rid=773486&cid=t_136511_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F08%2Flongevity-geneticswhats-old-is-new.html Today in the news there are reports of Dr. Jonathan Rothberg's plans to extract DNA from the saliva of 100 people over the age of 95. It was also posted on back in July on ABC. I would just like to bring attention to it again and compare this with the work that has already been done by one scientist.The idea is to study those who have lived a long time. Perhaps there is something in their make up which keeps them alive despite the stressors which all of us face. This is nothing new. Nir Barzilai at Albert Einstein College of Medicine has been doing this for years. I have been at several of his lectures. There is a nice video on SAGE Crossroads about what he is and has done.Rothberg's project is aptly named the Methselah Project after the famed biblical man who live to be 969 years of age. ... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=773486 Wed, 01 Aug 2007 14:48:00 +0100 773486