MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'analytical'. Sat, 03 Sep 2011 02:11:56 +0100 http://www.medworm.com/index.php?rid=5069472&cid=t_153734_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fmed-school-applicants-is-the-interview-becoming-as-influential-as-the-grades%2F2011.07.27 This week the Times ran a leading story on a new med school admission process, with multiple, mini-interviews, like speed dating. The idea is to assess applicants’ social, communication and ethical thinking (?) skills: …It is called the multiple mini interview, or M.M.I., and its use is spreading. At least eight medical schools in the United States — including those at Stanford, the University of California, Los Angeles, and the University of Cincinnati — and 13 in Canada are using it. At Virginia Tech Carilion, 26 candidates showed up on a Saturday in March and stood with their backs to the doors of 26 small rooms. When a bell sounded, the applicants spun around and read a sheet of paper taped to the door that described an ethical conundrum. Two minutes later, the bell sounded aga... Better Health blogs http://www.medworm.com/rss/comments.php?id=5069472 Wed, 27 Jul 2011 18:00:31 +0100 5069472 http://www.medworm.com/index.php?rid=4968908&cid=t_153734_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FoxxvlqvSqOs%2F Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us and we’ll share with it others. That’s right. Send us your announcements and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going, especially with all the layoffs. Despite the downsizing, there is movement. Here are some of the latest changes. Recognize anyone? And here is our regular feature. Send us a photo and we will spotlight a different person each week. This time around, we note that Health Market Science hired John Schultz, as executive vp of sales for all HMS business units, including life sciences and pharmacy. Previously, he was senior vp of sales and marketing at MedAssurant. And before that, he led sales and marketing... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4968908 Fri, 24 Jun 2011 12:00:22 +0100 4968908 http://www.medworm.com/index.php?rid=4934333&cid=t_153734_109_f&fid=34750&url=http%3A%2F%2Fpsychcentral.com%2Fblog%2Farchives%2F2011%2F06%2F15%2F4-fascinating-facts-you-might-not-know-about-carl-jung%2F In case you missed it, June 6th, 2011 marked the 50th anniversary of Swiss psychiatrist Carl Jung’s passing. Jung, born July 26, 1875, is one of the most compelling figures in psychology. Many people are familiar with Jung for his famous friendship and eventual split from Sigmund Freud, who considered their relationship at first to be one of father and son. Jung strongly disagreed with Freud’s sole emphasis on sex and other parts of his theories, and their relationship soon deteriorated. However, the two pioneers did agree on one thing: an individual must analyze his mind’s inner workings, including his dreams and fantasies. Jung founded analytical psychology, which emphasizes the importance of exploring both conscious and unconscious processes. According to one of his theories, all ... World of Psychology blogs http://www.medworm.com/rss/comments.php?id=4934333 Wed, 15 Jun 2011 10:12:12 +0100 4934333 http://www.medworm.com/index.php?rid=4436942&cid=t_153734_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FFoD7p_TQbwc%2F Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us and we’ll share with it others. That’s right. Send us your announcements and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going, especially with all the layoffs. Despite the downsizing, there is movement. Here are some of the latest changes. Recognize anyone? And here is our regular feature. Send us a photo and we will spotlight a different person each week. This time around, we note that Qforma hired Ted Pine as vice president of business development. He was previously vice president of sales at openQ, which markets programs for key opinion leader management and compliance, and was senior director of strategic accounts at Leade... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4436942 Fri, 04 Feb 2011 13:11:44 +0100 4436942 http://www.medworm.com/index.php?rid=4349677&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2011%2F01%2F14%2Ffishing_around_for_biomarkers.php Everyone in this industry wants to have good, predictive biomarkers for human diseases. We've wanted that for a very long time, though, and in most cases, we're still waiting. [For those outside the field, a biomarker is some sort of easy-to-run test that for a factor that correlates with the course of the real disease. Viral titer for an infection or cholesterol levels for atherosclerosis are two examples. The hope is to find a simple blood test that will give you advance news of how a slow-progressing disease is responding to treatment]. Sometimes the problem is that we have markers, but that no one can quite agree on how relevant they are (and for which patients), and other times we have nothing to work with at all. A patient's antibodies might, in theory, be a good place to look for m... In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=4349677 Fri, 14 Jan 2011 12:58:24 +0100 4349677 http://www.medworm.com/index.php?rid=4241934&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2010%2F12%2F08%2Fnasas_arsenic_bacteria_a_call_for_followup_experiments.php Since the posts here on the possible arsenic-using bacteria have generated so many comments, I'd like to try to bring things together. If you think that the NASA results need shoring up - and a lot of people do, including me - please leave a comment here about what data or new experiments you'd want to see. I'll assemble these into a new post and try to get some attention for it. The expertise among the readership here is largely in chemistry, so it would make sense to have suggestions from that angle - I assume that microbiologists are putting together their own lists elsewhere! I know that several readers have already put forward some ideas in the comment threads from the earlier posts - I'll go back and harvest those, but feel free to revise and extend your remarks for this one. So, t... In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=4241934 Wed, 08 Dec 2010 19:59:10 +0100 4241934 http://www.medworm.com/index.php?rid=4098410&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2010%2F10%2F22%2Fthe_latest_technology.php Well, the latest for 1960, anyway. That's the Bruker KIS-1 NMR machine there, folks, operating at 25 MHZ, and ready to dim the lights in the whole building when you switch on that electromagnet. Allow about 12 hours of acquisition time to get a decent spectrum. For those of you outside the field, a 300 MHZ NMR machine is now considered a average workhorse instrument, and should give you a spectrum (with resolution that would have made someone back then faint with joy) in a minute or so of acquisition time. We can do things with modern machines that they wouldn't have even dreamed of back in 1960, and people are still thinking up new tricks. All hail NMR! (Source: In the Pipeline) In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=4098410 Fri, 22 Oct 2010 15:35:28 +0100 4098410 http://www.medworm.com/index.php?rid=3823147&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2010%2F08%2F04%2Frunning_your_fingers_over_a_single_molecule.php Readers will remember the extraordinary pictures of individual pentacene molecules last fall. Well, the same IBM team, working with a group at Aberdeen, has struck again. This time they've imaged a much more complex organic molecule, cephalandole A. As that link details, the structure of this natural product has recently been revised - it's one of those structural-isomer problems that NMR won't easily solve for you. Here's a single molecule of it, imaged by the same sort of carbon-monoxide-tipped atomic force microscope probe used in the earlier work> Now, it's not like you can just look at that and draw the structure, although it is vaguely alarming to see the bonding framework begin to emerge. If you calculate the electon densities around the structure, though, it turns out that the re... In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=3823147 Wed, 04 Aug 2010 15:02:19 +0100 3823147 http://www.medworm.com/index.php?rid=3699497&cid=t_153734_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fmicrobiology-and-the-cooties-epidemic%2F2010.06.25 Remember “cooties” in grade school? You know, the germs or disease that girls gave boys or boys gave girls in grade school if they touched? Well, it seems they’re becoming an epidemic. Thank goodness someone checked for “cooties” on the Stanley Cup: The NHL champion Blackhawks’ beloved trophy stopped by the Chicago Tribune newsroom, and so we took the opportunity to do something the Cup’s keeper said had never been done: We swabbed it for germs. We sent the samples to the Chicago lab EMSL Analytical, which found very little general bacteria and no signs of staph, salmonella or E. coli. “It’s surprisingly clean,” lab manager Nancy McDonald said. Just 400 counts of general bacteria were found, she said. By comparison, a desk in an o... Better Health blogs http://www.medworm.com/rss/comments.php?id=3699497 Fri, 25 Jun 2010 14:00:00 +0100 3699497 http://www.medworm.com/index.php?rid=3585818&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2010%2F05%2F20%2Ffloyd_landis_the_isotopes_werent_lying_after_all.php This post from 2006 on the science behind Floyd Landis's suspicious steroid blood tests set my blog record for comments - the debate went on and on about Landis, about the lab that reported the results, about how the samples were handled, etc. Well, Landis has now admitted using performance-enhancing drugs for most of his career. Widely, expensively, and thoroughly did he use them. The blood test was correct. Carbon isotopes don't lie. (Source: In the Pipeline) In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=3585818 Thu, 20 May 2010 16:07:45 +0100 3585818 http://www.medworm.com/index.php?rid=3508437&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2010%2F04%2F27%2Fmasses_of_data_in_every_sample.php I've said several times that I think that mass spectrometry is taking over the analytical world, and there's more evidence of that in Angewandte Chemie. A group at Justus Liebig University in Giessen has built what has to be the finest imaging mass spec I've ever seen. It's a MALDI-type machine, which means that a small laser beam does the work of zapping ions off the surface of the sample. But this one has better spatial resolution than anything reported so far, and they've hooked it up to a very nice mass spec system on the back end. The combination looks to me like something that could totally change the way people do histology. For the non-specialist readers in the audience, mass spec is a tremendous workhorse of analytical chemistry. Basically, you use any of a whole range of techniq... In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=3508437 Tue, 27 Apr 2010 11:17:52 +0100 3508437 http://www.medworm.com/index.php?rid=3071456&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2009%2F12%2F09%2Fwater_and_proteins_inside_cells_sloshing_around_or_not.php Back in September, talking about the insides of cells, I said: There's not a lot of bulk water sloshing around in there. It's all stuck to and sliding around with enzymes, structural proteins, carbohydrates, and the like. . ." But is that right? I was reading this new paper in JACS, where a group at UNC is looking at the NMR of fluorine-labeled proteins inside E. coli bacteria. (It's pretty interesting, not least because they found that they can't reproduce some earlier work in the field, for reasons that seem to have them throwing their hands up in the air). But one reference caught my eye - this paper from PNAS last year, from researchers in Sweden. That wasn't one that I'd read when it came out - the title may have caught my eye, but the text rapidly gets too physics-laden for me to ... In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=3071456 Wed, 09 Dec 2009 13:45:07 +0100 3071456 http://www.medworm.com/index.php?rid=3067137&cid=t_153734_109_f&fid=38950&url=http%3A%2F%2Fwww.shockmd.com%2F2009%2F12%2F08%2Flove-is-great-for-creativity-sex-for-analytical-thinking%2F Most people think that love and sex are tightly related. Nevertheless the size of the overlap between these two varies with culture, history, education and social values. In the United States, males report having less problems imagining sex without love than females do; in China, however the link between love and romance seems to be generally less pronounced than in Western cultures; and in the West, the views of sexuality and love differed between the Victorian and the Freudian eras On a neurobiological level the brain systems for love, sex and attachment communicate and coordinate with one another. But if love and lust aren’t completely the same, what different psychological effects do they have in humans? Researchers from The Netherlands and Germany proposed a cognitive model for... Dr Shock MD PhD blogs http://www.medworm.com/rss/comments.php?id=3067137 Tue, 08 Dec 2009 07:40:18 +0100 3067137 http://www.medworm.com/index.php?rid=2762004&cid=t_153734_122_f&fid=36582&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FSharpBrains%2F%7E3%2FYWJmrAaDs8I%2F (Editor's Note: we are pleased to bring you this article thanks to our collaboration with Greater Good Magazine.) Changing our Minds By imagining many possible worlds, argues novelist and psychologist Keith Oatley, fiction helps us understand ourselves and others. -By Keith Oatley For more than two thousand years people have insisted that reading fiction is good for you. Aristotle claimed that poetry—he meant the epics of Homer and the tragedies of Aeschylus, Sophocles, and Euripides, which we would now call fiction—is a more serious business than history. History, he argued, tells us only what has happened, whereas fiction tells us what can happen, which can stretch our moral imaginations and give us insights into ourselves and other people. This is a strong argument for schools to c... SharpBrains blogs http://www.medworm.com/rss/comments.php?id=2762004 Wed, 02 Sep 2009 22:27:46 +0100 2762004 http://www.medworm.com/index.php?rid=2556344&cid=t_153734_149_f&fid=35784&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FTheChemBlog%2F%7E3%2FrcCWFvB1Qmk%2F The US supreme court ruled a few weeks ago that the chemists that perform tests in forensic analysis are not immune from cross examination by defense attorneys.  It’s not surprising that the American judicial system did not inherently allow for this, since it’s a very biased and f.ed up system.  With this tool in the briefs of attorneys, it sets up a very real and very likely chance that a number of methods used in forensic science, as conducted in the state crime labs, will not hold up to scrutiny.  Not because they’re necessarily invalid (though, we shall see about that), but because they’ve not been done with the appropriate controls – an argument mentioned in the majority arguments by Scalia: He cited one report, for example, that said “there is wide ... The Chem Blog blogs http://www.medworm.com/rss/comments.php?id=2556344 Tue, 30 Jun 2009 13:14:58 +0100 2556344 http://www.medworm.com/index.php?rid=1815727&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2008%2F09%2F23%2Fyou_call_that_an_xray_source.php Over the years, when some puzzling feature of a drug candidate’s binding to a target came up, I’ve often said “Well, we’re not going to know what’s happening until some lunatic builds a femtosecond X-ray laser”. Various lunatics are now pitching in to build some. I’m going to have to revise my lines. The reason I’d say such a mouthful is that we already, of course, get a lot of structural information from X-ray beams. Shining them through crystals of various substances can, after a good deal of number-crunching in the background, give you a three-dimensional picture of how the unit molecules have packed together. Proteins can be crystallized, too, although it can be something of a black art, and they can be either crystallized with or soaked with our small molecules, givin... In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=1815727 Tue, 23 Sep 2008 12:10:04 +0100 1815727 http://www.medworm.com/index.php?rid=1764219&cid=t_153734_149_f&fid=35776&url=http%3A%2F%2Fpipeline.corante.com%2Farchives%2F2008%2F09%2F04%2Fxray_structures_handle_with_care.php X-ray crystallography is wonderful stuff – I think you’ll get chemists to generally agree on that. There’s no other technique that can provide such certainty about the structure of a compound – and for medicinal chemists, it has the invaluable ability to show you a snapshot of your drug candidate bound to its protein target. Of course, not all proteins can be crystallized, and not all of them can be crystallized with drug ligands in them. But an X-ray structure is usually considered the last word, when you can get one – and thanks to automation, computing power, and to brighter X-ray sources, we get more of them than ever. But there are a surprising number of ways that X-ray data can mislead you. For an excellent treatment of these, complete with plenty of references to the rece... In the Pipeline blogs http://www.medworm.com/rss/comments.php?id=1764219 Thu, 04 Sep 2008 12:41:13 +0100 1764219 http://www.medworm.com/index.php?rid=1635189&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D2321 Kudos to Agilent Technologies for being a bit zany in its advertising. A new “music video” brings Barry White sound to the Mass Spec crowd (courtesy of Agilent Technologies)….and hat tip to Chris Truelove, Pharma Blogs in Review. AMS (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1635189 Thu, 17 Jul 2008 21:02:07 +0100 1635189 http://www.medworm.com/index.php?rid=1631586&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D2301 We received an office visit today from Dr. Prabir Basu, executive director of the National Institute for Pharmaceutical Technology and Education, or NIPTE. (He’s also head of Purdue University’s Pharmaceutical Technology Education Center.) NIPTE, in case you haven’t heard, is a not-for-profit consortium of 11 universities whose mission is to further scientific education and training [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1631586 Wed, 16 Jul 2008 21:11:14 +0100 1631586 http://www.medworm.com/index.php?rid=1526782&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D2041 After numerous travel delays and “customer service” by surly ground crew, I finally arrived to face the blazing heat of summertime in Phoenix, AZ. I like the laissez faire customer service of today’s airline industry just about as much as I enjoy 105 degree temperatures. However, I was excited to attend Honeywell’s 2008 User Group [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1526782 Tue, 17 Jun 2008 17:30:19 +0100 1526782 http://www.medworm.com/index.php?rid=1526783&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D2021 That’s how Control magazine’s executive editor Jim Montague described the pharmaceutical industry in a recent and very memorable op-ed (read it here), in which he interviews experts including E-55 insider Gawayne Mahboubian-Jones. Jim brings to the the “so what” detachment of one who has covered PAT and process control as it has advanced in other industries over [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1526783 Tue, 17 Jun 2008 03:20:32 +0100 1526783 http://www.medworm.com/index.php?rid=1516790&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1951 Ever see the old Abbott and Costello “who’s on first” baseball routine?  “I don’t know” was on third base. Pharma is not the only industry that suffers from less-than-perfect supply chain risk management, as Juran Institute CEO Joe De Feo pointed out in a recent audio interview.  As the heparin tragedy has pointed out, many companies may not [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1516790 Fri, 13 Jun 2008 15:21:37 +0100 1516790 http://www.medworm.com/index.php?rid=1488708&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1881 Just filing a few more notes on the Yale Green Processing conference from last week.  Afternoon sessions during the first day focused on the “hot” topic of continuous processing and use of process intensification to improve reaction chemistry. The question above came up; supporters for the concept of using multiple microreactors in series or parallel [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1488708 Tue, 03 Jun 2008 01:54:27 +0100 1488708 http://www.medworm.com/index.php?rid=1480919&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1871 Sharon Flank, CEO of InfraTrac (which has commercialized a potential anticounterfeiting solution) recently wrote about what she saw during a recent trip to Hong Kong.  Read on for more. (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1480919 Fri, 30 May 2008 23:36:48 +0100 1480919 http://www.medworm.com/index.php?rid=1449574&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1811 OK, Rockville’s a long way from Miami…but the analytical detective work that FDA, MIT scientists and some companies did into potential root causes of heparin contamination makes a great whodunit.  C&EN, an outstanding publication, beat us to it by several months with this gem, published in late November. In case you missed it, here it is. There are [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1449574 Fri, 16 May 2008 18:07:44 +0100 1449574 http://www.medworm.com/index.php?rid=1311477&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1591 Forget about championing one side or another. The politically charged “generics vs. namebrand drug” debate offers an opportunity to study the impacts of process and ingredient variability on drug manufacturing and on clinical effects in patients.   (For material to analyze, click here). At IFPAC 2008 in January, FDA’s Dr. Janet Woodcock noted the fact that [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1311477 Tue, 18 Mar 2008 13:20:37 +0100 1311477 http://www.medworm.com/index.php?rid=1309132&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1581 …taught by Jack Carroll and Emil Ciurczak….tune in here. (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1309132 Mon, 17 Mar 2008 21:53:54 +0100 1309132 http://www.medworm.com/index.php?rid=1256361&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1471 Spatially Offset Raman Spectroscopy (SORS—oh, no, not another analytical acronym) , under development in the U.K. at academic labs and a spinoff, promises to facilitate non-invasive testing in the pharmaceutical industry. For more information, read on. (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1256361 Tue, 26 Feb 2008 03:07:17 +0100 1256361 http://www.medworm.com/index.php?rid=1232040&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1444 To some people, Process Analytical Technologies (PAT) and Quality by Design (QbD) might seem like the dullest topics imagineable.  But they just might be the salvation of an industry dogged by recalls and adverse reaction reports, lawsuits, 483’s and other compliance issues (and that’s just on the GMP and non sales and marketing side!) We think [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1232040 Thu, 14 Feb 2008 16:41:22 +0100 1232040 http://www.medworm.com/index.php?rid=1188769&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1437 We love the progressive thinking that’s going on in pharma. That’s why I enjoy my job and what makes covering this side of the industry so much more interesting and positive than looking at the financial side and all the marketing scandals. As we do every year, we’ve covered this year’s IFPAC process analytics conference, [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1188769 Wed, 30 Jan 2008 18:32:42 +0100 1188769 http://www.medworm.com/index.php?rid=1187241&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1435 Our editors are keeping busy at the IFPAC 2008 Show in Baltimore. Check our landing page for daily show coverage including video interviews, articles, and product announcements. IFPAC 2008 Show Coverage (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1187241 Tue, 29 Jan 2008 22:47:16 +0100 1187241 http://www.medworm.com/index.php?rid=1158450&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1432 This is pretty old news, but it certainly took me by surprise. Just glanced at the online masthead and the byline of an article from the November 2007 issue of Biopharm International and learned that Dr. Hussain has moved from Sandoz to… Philip Morris International?  (OK.  Talk amongst yourselves….) His new title is :  Vice President of [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1158450 Thu, 17 Jan 2008 14:37:44 +0100 1158450 http://www.medworm.com/index.php?rid=1022536&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1382 The American Association of Pharmaceutical Scientists (AAPS) has announced its 2007 AAPS Fellows, cited for making “remarkable scholarly and research contributions to the pharmaceutical sciences.” They will be recognized at the group’s annual meeting this week in San Diego, which Bill Swichtenberg will be attending. Congratulations to each and every one of them.  (If PhRMA would [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=1022536 Mon, 12 Nov 2007 16:10:01 +0100 1022536 http://www.medworm.com/index.php?rid=976757&cid=t_153734_122_f&fid=36582&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FSharpBrains%2F%7E3%2F174600734%2F Charles Darwin (1809-1882)'s autobiography (full text free online) includes some very insightful refections on the evolution of his own mind during his middle-age, showcasing the power of the brain to rewire itself through experience (neuroplasticity) during our whole lifetimes-not just when we are youngest. He wrote these paragraphs at the age of 72 (I have bolded some key sentences for emphasis, the whole text makes great reading): "I have said that in one respect my mind has changed during the last twenty or thirty years. Up to the age of thirty, or beyond it, poetry of many kinds, such as the works of Milton, Gray, Byron, Wordsworth, Coleridge, and Shelley, gave me great pleasure, and even as a schoolboy I took intense delight in Shakespeare, especially in the historical plays.... SharpBrains blogs http://www.medworm.com/rss/comments.php?id=976757 Thu, 25 Oct 2007 01:22:23 +0100 976757 http://www.medworm.com/index.php?rid=961810&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1335 Polymorphism, a condition in which an active ingredient can exist in more than one crystal form (each with a potentially different impact), has long bedeviled drug makers and QA/QC departments. Researchers in the U.K. (at the University of Warwick and AstraZeneca) have discovered a new way of using NMR that can detect polymorphism in crystalline [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=961810 Thu, 18 Oct 2007 18:10:48 +0100 961810 http://www.medworm.com/index.php?rid=961813&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1332 Big Pharma may be feeling the cost pinch in manufacturing, but generic pharma feels it much, much more.  Recently, two experts at Dr. Reddy’s Laboratories in India discussed the drive to smaller pharma batches and the need for better line balancing.  Note their mention of PAT.  For more, read on.   Manufacturing should be more closely tied to supply chain [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=961813 Thu, 18 Oct 2007 16:30:50 +0100 961813 http://www.medworm.com/index.php?rid=944712&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1326 At the very least, let’s rename QbD “Intelligent Design.” That way, columnist Emil Ciurczak quips, we can get faith-based government funding to teach it in U.S. public schools.  For more on Quality by Design and the disconnect with some Pharma H.R. departments read Emil’s latest column (posted below for the link-averse): -AMS The Perfect Storm* I was perusing the “Positions Available” section of Chemical [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=944712 Thu, 11 Oct 2007 15:40:49 +0100 944712 http://www.medworm.com/index.php?rid=770842&cid=t_153734_150_f&fid=35779&url=http%3A%2F%2Fwww.pharmamanufacturing.com%2Fonpharma%2F%3Fp%3D1297 There are no whole truths; all truths are half-truths. It is trying to treat them as whole truths that plays the devil.”b       “Truth is rarely pure, and never simple.”c       The news is again a-twitter with stories of another fallen hero: Avandia. While I have no need for the drug, it seems to echo the Vioxx and Celebrex [...] (Source: On Pharma) On Pharma blogs http://www.medworm.com/rss/comments.php?id=770842 Tue, 31 Jul 2007 17:25:25 +0100 770842 http://www.medworm.com/index.php?rid=478755&cid=t_153734_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F03%2F06%2Fthe-first-urine-test-to-detect-insulin-doping-in-athletes%2F Filed under: Type 1, Type 2, Childhood, Adult Onset, Lifestyle, Drugs, SupportScientists in Germany are reporting development of a urine test that finally can identify athletes who misuse certain kinds of insulin in an illicit attempt to enhance performance. An article scheduled to appear in an April edition of Analytical Chemistry says it is possible to detect the misuse of insulin in a urine sample. Scientists had not attempted to develop a test in the past because of the presumption that it was impossible to detect misuses of insulin. Because insulin is rationed and used efficiently by the body, a byproduct of insulin would be theoretically undetectable. However, with the advent of the newer long-acting insulin analogues, scientists are now able to identify degradation product in the ur... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=478755 Tue, 06 Mar 2007 05:00:00 +0100 478755