MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'antagonist'. Sat, 03 Sep 2011 02:53:10 +0100 http://www.medworm.com/index.php?rid=4968494&cid=t_178406_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fwhen-is-it-appropriate-to-disregard-guidelines-in-medical-care%2F2011.06.24 Podcast: In an article appearing last week in the American Heart Journal, investigators concluded that if American doctors would prescribe for their patients with heart failure each of the six therapies which are most strongly recommended in current heart failure guidelines, 68,000 lives per year could be saved. The following (for the interest of the reader, and for the convenience of any attorneys who may follow DrRich’s offerings), is an ordered list of these six proven, life-saving heart failure therapies, along with the number of American lives that could be saved each year if only American doctors would stop grossly under-utilizing them in violation of published guidelines: aldosterone antagonist therapy – 21,407 lives beta blockers – 12,922 lives implantable defibrillators ... Better Health blogs http://www.medworm.com/rss/comments.php?id=4968494 Fri, 24 Jun 2011 21:00:47 +0100 4968494 http://www.medworm.com/index.php?rid=4245613&cid=t_178406_151_f&fid=36896&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FSuboxoneTalkZone%2F%7E3%2FNlNRq7VNamk%2F Physical dependence vs. addiction Tolerance and withdrawal are signs of ‘physical dependence’ on a substance.  Addiction, on the other hand, is a complicated term that has different meanings in different contexts, but generally refers to an obsession or attachment to a behavior, person, or substance.  Many people mistakenly consider physical dependence and addiction to be the same.  To illustrate the difference, there are many medications that cause physical dependence that are not addictive.  Effexor and Paxil, two common antidepressants, cause physical dependence and have very uncomfortable withdrawal symptoms.  Physical dependence occurs in non-psychiatric medications as well; suddenly stopping some blood pressure medications will cause an upward spike in blood pressure... Suboxone Talk Zone blogs http://www.medworm.com/rss/comments.php?id=4245613 Fri, 10 Dec 2010 03:05:34 +0100 4245613 http://www.medworm.com/index.php?rid=2458375&cid=t_178406_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FRdUHmqA3XeA%2F My heart breaks when I see photos of children suffering from genetic disorders, such as the nine babies from this story. But this story also lauds to the use of genetically modified organisms for producing drugs for treatment. Recently, scientists discovered a new genetic disorder in nine newborn to 2-week old babies. The infants had swollen bone tissues, bone pain and deformity, and rashes that can range in size from small fluid-filled blisters or pustules to blisters that covered the whole body. The researchers immediately realized they were looking at an unrecognized auto-inflammatory syndrome, where recurring episodes of inflammation occur without any pathogens or immune cells triggering the reaction. All nine babies had mutations of IL1RN, a gene involved in the immune response whic... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2458375 Fri, 05 Jun 2009 20:34:11 +0100 2458375 http://www.medworm.com/index.php?rid=1376693&cid=t_178406_109_f&fid=34750&url=http%3A%2F%2Fpsychcentral.com%2Fblog%2Farchives%2F2008%2F04%2F16%2Fcp-316-311-fails-trials-pfizer%2F An experimental drug, called CP-316, 311 and made by Pfizer, was as effective as placebo (a sugar pill) in its initial clinical trials. At the interim analysis to determine efficacy, the researchers found the drug not to be working to help people with depression, and so the trial was terminated. CP-316, 311 is a selective nonpeptide antagonist of corticotropin-releasing hormone type 1 (CRH1) receptors. Hormone receptors? you might ask. Well, it turns out that the corticotropin-releasing hormone (CRH) system has been implicated as a possible contributing factor (or, perhaps, cause) of several psychiatric disorders, including major depressive disorder. Back to the drawing board for Pfizer. Reference: Binneman, B., Feltner, D., Kolluri, S., Shi, Y., Qiu, R. & Stiger, T. (2008). A 6-W... World of Psychology blogs http://www.medworm.com/rss/comments.php?id=1376693 Wed, 16 Apr 2008 12:03:15 +0100 1376693 http://www.medworm.com/index.php?rid=1133982&cid=t_178406_134_f&fid=36049&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FDiabetesNotes%2F%7E3%2F212714380%2F This study showed that blocking GIP activity using (Pro3)GIP in mice with established, high fat diet-induced obesity and diabetes results in significant weight loss, improvement of insulin resistance and amelioration of diabetes. Researchers are now examining the findings as an interesting new way to battle obesity and metabolic disorders. Share This (Source: Diabetes Notes) Diabetes Notes blogs http://www.medworm.com/rss/comments.php?id=1133982 Mon, 07 Jan 2008 18:09:39 +0100 1133982