MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'aspirin'. Sat, 03 Sep 2011 01:52:21 +0100 http://www.medworm.com/index.php?rid=5069479&cid=t_103336_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fnsaids-might-be-risky-for-people-with-heart-problems%2F2011.07.26 As if people with the combination of high blood pressure and heart disease don’t already have enough to worry about, a new study suggests that common painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) pose special problems for them. Among participants of an international trial called INVEST, those who often used NSAIDs such as ibuprofen (Advil, Motrin and others), naproxen (Aleve, Naprosyn, and others), or celecoxib (Celebrex) were 47% more likely to have had a heart attack or stroke or to have died for any reason over three years of follow-up than those who used the drugs less, or not at all. The results were published in the July issue of the American Journal of Medicine. Millions of people take NSAIDs to relieve pain and inflammation. They are generally safe and effectiv... Better Health blogs http://www.medworm.com/rss/comments.php?id=5069479 Tue, 26 Jul 2011 14:00:35 +0100 5069479 http://www.medworm.com/index.php?rid=4853221&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2Fpok9CMr79cQ%2F Hello, everyone, and welcome to the working week. Another overcast day is unfolding here on the Pharmalot corporate campus, where we will be hosting a webinar on the injectable delivery drug market, so please join us. Meanwhile, the time has come to grab a cup of stimulation and peruse the news of the world. Hope your day goes well and stay in touch… FDA Approves Vertex Pharma Hepatitis C Drug (Reuters) Lilly Helps Create Biotech To Develop And Sell Xigris (Associated Press) How PR Tactics Skew Medical Research Presentation (The Guardian) J&J Woes Mitigated By New Drug Bets? (Bloomberg News) Lilly Chops 70 Jobs In Ireland (InPharm) Two Men Convicted Of Selling HIV Meds (NewJerseyNewsroom) Google Warned About Rogue Drug Ads (Wall Street Journal) Provenge, Medicare And Costs (CNBC... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4853221 Mon, 23 May 2011 11:59:53 +0100 4853221 http://www.medworm.com/index.php?rid=4464706&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2Fl26BfErWhfw%2F And so, once again, another working week draws to a close. Already, we are penciling in our weekend plans - a stroll with the official Pharmalot mascots, spending time with our short people and maybe a nap or two. What about you? Will there be a chance to read a book or watch a movie? How about spending time with a special someone? Or maybe take a nap? Whatever you do, enjoy. Meanwhile, here are a few tidbits. Catch you soon… Cephalon Receives Subpoena From US Postal Service Over Provigil (Reuters) FDA To Outsource More Overseas Plant Inspections (Bloomberg News) J&J Cordis Unit Cuts Sales Jobs (Reuters) Gilead Files Again For HIV Drug Approval (Silicon Valley Business Journal) Bristol-Myers And Pfizer Clotbuster Beats Aspiring In Study (HealthDay) Pfizer And EPA To Clean Up Con... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4464706 Fri, 11 Feb 2011 13:00:21 +0100 4464706 http://www.medworm.com/index.php?rid=4419280&cid=t_103336_122_f&fid=35055&url=http%3A%2F%2Fwww.sarasotaneurology.com%2Fmedia%2FSarasota-Neurology-Podcast-Stroke-Prevention-201102 In this episode of the Sarasota Neurology Podcast, Dr. Kassicieh, a recognized expert in stroke prevention, provides an overview of  current techniques for preventing and managing risk of stroke. Stroke is the third leading cause of death in the United States. This combined with heart attacks and heart disease result in over 2 million deaths a year. The common underlying cause is vascular disease or hardening of the arteries. Heart attack and stroke can be prevented with simple life style changes and medications. Treatment of high cholesterol, high blood pressure, aspirin and stop smoking will significantly lower risk of suffering from these devastating conditions. Listen to this report to find out how you can reduce your risk of suffering from a stroke, heart attack or other cardiovascu... Sarasota Neurology blogs http://www.medworm.com/rss/comments.php?id=4419280 Mon, 31 Jan 2011 17:53:40 +0100 4419280 http://www.medworm.com/index.php?rid=4253137&cid=t_103336_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fdecline-in-stroke-deaths-reinforces-brain-attack-prevention%2F2010.12.13 Stroke killed 2,000 fewer Americans in 2008 (the last year with complete numbers) than it did in 2007, the Centers for Disease Control and Prevention (CDC) said yesterday in its latest annual Deaths report. That dropped stroke from the third leading cause of death in the United States to the fourth. Good news? Yes and no. It’s always good news when fewer people die. The reduction suggests a payoff for efforts to prevent stroke and improve the way doctors treat it. Yet the drop from third to fourth place is due largely to an accounting change. The CDC reorganized another category, “chronic lower respiratory diseases” (mainly chronic bronchitis and emphysema), to include complications of these diseases such as pneumonia. The change substantially increased the number of deaths in this c... Better Health blogs http://www.medworm.com/rss/comments.php?id=4253137 Mon, 13 Dec 2010 13:00:25 +0100 4253137 http://www.medworm.com/index.php?rid=4245603&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FmW_dDStfJV4%2F Hello, everyone. Another sunny - and cold - day here on the Pharmalot corporate campus, where we are, as usual, hustling the short people off to this or that school house. To keep warm, we are brewing the mandatory cup of stimulation and searching for some hot news. Meanwhile, here are a few items of interest. We hope your days goes well. Do stay in touch… Pfizer Names Simmons As Head Of Emerging Markets (Bloomberg News) Teva’s MS Drug Meets Primary Endpoint (Reuters) Nigeria Denies Blame For Delay In Pfizer Payments (AllAfrica) India Will Not Compromise Local Pharma In EU Pact (LiveMint) Roche Advances Schizophrenia And MS Drugs (Reuters) Daily Aspirin Slashes Cancer Risk: Study (PharmaTimes) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4245603 Thu, 09 Dec 2010 13:00:39 +0100 4245603 http://www.medworm.com/index.php?rid=4159276&cid=t_103336_107_f&fid=36672&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FSciencebaseScienceBlog%2F%7E3%2FZfVMnbGkAHs%2Falcohol-effects-giant-testicles-pennycress-diesel.html An alcoholic FAQ – Aspirin and other drugs prevent the enzyme alcohol dehydrogenase (found in the stomach and liver) from breaking down alcohol, thus slowing the liver’s ability to metabolise alcohol and so it accumulates in your blood faster and has longer-lasting effects, which means you get drunk faster and say drunk longer, but you will have an almighty hangover too (one that aspirin will not cure) The biggest balls of all – The largest testicles by mass as a proportion of body mass are those of the bush cricket. According to behavioural ecologist Karim Vahed who has presumably had a good look, the tuberous bush cricket has testes accounting for 14% of its body mass. Making pennycress pay its way – I'd never heard of this weed until today, but apparently, p... Sciencebase Science Blog blogs http://www.medworm.com/rss/comments.php?id=4159276 Wed, 10 Nov 2010 16:29:19 +0100 4159276 http://www.medworm.com/index.php?rid=4151855&cid=t_103336_107_f&fid=36672&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FSciencebaseScienceBlog%2F%7E3%2FZfVMnbGkAHs%2Falcohol-effects-giant-testicles-pennycress-diesel.html An alcoholic FAQ – Aspirin and other drugs prevent the enzyme alcohol dehydrogenase (found in the stomach and liver) from breaking down alcohol, thus slowing the liver’s ability to metabolise alcohol and so it accumulates in your blood faster and has longer-lasting effects, which means you get drunk faster and say drunk longer, but you will have an almighty hangover too (one that aspirin will not cure) The biggest balls of all – The largest testicles by mass as a proportion of body mass are those of the bush cricket. According to behavioural ecologist Karim Vahed who has presumably had a good look, the tuberous bush cricket has testes accounting for 14% of its body mass. Making pennycress pay its way – I'd never heard of this weed until today, but apparently, p... Sciencebase Science Blog blogs http://www.medworm.com/rss/comments.php?id=4151855 Wed, 10 Nov 2010 16:29:19 +0100 4151855 http://www.medworm.com/index.php?rid=3987017&cid=t_103336_87_f&fid=34872&url=http%3A%2F%2Fblisstree.com%2Ffeel%2F200791%2F Aspirin Prevents Colon Cancer: A new study found that daily use of low-dose aspirin cuts colorectal cancer risk by a third. (via ABC News) Post from: BlissTree (Source: Healthbolt) Healthbolt blogs http://www.medworm.com/rss/comments.php?id=3987017 Mon, 20 Sep 2010 17:15:15 +0100 3987017 http://www.medworm.com/index.php?rid=3798819&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FM-x7b-V2W30%2F After an intriguing debate over the mysterious outcome of a clinical trial, an FDA advisory committee has voted 7-to-1 to recommend that the agency approve AstraZeneca’s Brilinta blood thinner. The outcome increases the likelihood the FDA will, in fact, endorse the medication, even though a clinical trial found an unexpected - and adverse - result only in patients from the US. The key clinical trial compared Brilinta to Plavix in 18,624 patients in 43 countries who were being treated for a blocked artery or heart attack. The results showed the med reduced heart attacks, strokes and cardiovascular death 16 percent compared with Plavix after a year’s treatment. And all of the patients were given aspirin. But about 9 percent - who were from the US - saw no benefit. The FDA had exp... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3798819 Wed, 28 Jul 2010 21:55:50 +0100 3798819 http://www.medworm.com/index.php?rid=3683870&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FQ3WgLWefK3Q%2F Four years ago, Boehringer Ingelheim set out to prove that its Aggrenox heart drug could beat a basic dose of aspirin in preventing strokes. The results came back in March, but the drugmaker hasn’t worked very hard to publicize them. Why? The trial was a bust - Aggrenox failed to meet the primary endpoint of reducing the risk of secondary ischemic stroke in 1,294 patients in Japan. The incidence among patients given Aggrenox was 6.9 percent compared with 5 percent for those on aspirin (look here). This is a problem for Boehringer, which markets Aggrenox to “reduce the risk of a subsequent stroke in patients who have had a transient ischemic attack, or TIA, or stroke due to a blood clot.” After all, Aggrenox is rather pricey, costing about $3 per pill, and it must be taken... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3683870 Mon, 21 Jun 2010 12:52:49 +0100 3683870 http://www.medworm.com/index.php?rid=3607559&cid=t_103336_109_f&fid=34750&url=http%3A%2F%2Fpsychcentral.com%2Fblog%2Farchives%2F2010%2F05%2F27%2Faspirin-for-schizophrenia%2F Could inflammation be a contributing factor to some symptoms in schizophrenia? And if inflammation is a significant factor in schizophrenia, could ordinary aspirin help? Researchers (Lann et al., 2010) from the Netherlands (I love researchers from the Netherlands!) set to find out. They looked at 70 inpatients in ten psychiatric hospitals who were already taking antipsychotic medications to help treat their schizophrenia (or a related schizophrenia disorder). They randomly divided the 70 patients into two groups — a control group that received placebo, and another group who received 1,000 mg of aspirin per day. Patient functioning and psychopathology was tested with a common assessment, the Positive and Negative Syndrome Scale (PANSS). The researchers also looked at cognitive functio... World of Psychology blogs http://www.medworm.com/rss/comments.php?id=3607559 Thu, 27 May 2010 21:19:03 +0100 3607559 http://www.medworm.com/index.php?rid=3404143&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FuzDwPCt43xM%2F Top of the morning to you. We are hustling about as we get ready to deliver the short people to various schoolhouses. But as you know, we enjoy challenges. Of course, another challenge beckons - preparing for the day ahead. With meetings and deadlines looming, here are a few items that should help. Good luck, everyone, and keep in touch… UBS Broker Charged In Insider Trading Pharma Case (NBC New York) Biogen And Elan Plan Tysabri-Comparison Study (MarketWatch) Medicare Panel Sees Anemia Drug Risks In Kidney Patients (Reuters) Two AVI BioPharma Directors Won’t Return (press release) Aspirin Use In Unexplained Recurrent Miscarriage Studied (HealthDay) Coffee pix thx to chichcacha flickr creative commons (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3404143 Thu, 25 Mar 2010 11:50:21 +0100 3404143 http://www.medworm.com/index.php?rid=3408340&cid=t_103336_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D8446 Our Cardiologist blogger, Heart of the Matter, has an update on Aspirin in the primary prevention of heart attacks. Primary prevention means preventing something which has not happened, and in the case of aspirin, it means people who have not had a heart attack before but take aspirin to prevent one from ever happening. At the just concluded ACC Annual Scientific Meeting at Atlanta, Georgia, Dr Jay Das and group re-reviewed the ATTC data, plus another three aspirin trials ( the JPAD, POPADAD, AAA ) and also concluded basically, that althought there was some small benefit with aspirin, there was a significant level of side effects. They concluded that there was no role for aspirin in the primary prevention of heart attacks. So once again, the message needs to go out to primary care doctors ... Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=3408340 Thu, 25 Mar 2010 00:00:00 +0100 3408340 http://www.medworm.com/index.php?rid=3395249&cid=t_103336_117_f&fid=38158&url=http%3A%2F%2Fwww.twitter.com%2Famacupuncturehttp%3A%2F%2Famericanacupuncture.blogspot.com%2F2010%2F03%2Fis-daily-aspirin-harmful-or-helpful.html Does an aspirin a day, keep the doctor away?  Millions of people today are taking aspirin for primary prevention of heart disease. Half of men over 50, take daily low-dose aspirin.  Can  doctors tell those who are healthy, to stop?As a medical physician for over 51 years, I strive to give you the best medical information on controversial medical subjects, and help your read betwwen the lines. You must come to your own conclusions. I have no ties to any organization, pharmaceutical, or lobby group. As an practicing medical acupuncturist since 1982, I find western medicine and medical acupuncture are very complimentary. This results in astounding healing in pain management, addictions to cigarettes and food, and a host of other maladies. Visit drneedles is blogg... Dr. Needles Medical Blogs blogs http://www.medworm.com/rss/comments.php?id=3395249 Tue, 23 Mar 2010 14:25:00 +0100 3395249 http://www.medworm.com/index.php?rid=3370342&cid=t_103336_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F03%2F16%2Fjournal-of-the-american-medical-association-2010-vol-303-no-9%2F This article aims to determine the effectiveness of aspirin in preventing events in people with a low ABI identified on screening the general population. An NHS Athens password is required to access this article online or contact the library for a print copy. Filed under: Current Awareness, E-Journals, Journals Tagged: Ankle Brachial Index, Aspirin, Atherosclerosis, Cardiovascular Disease, Stroke (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3370342 Tue, 16 Mar 2010 12:02:16 +0100 3370342 http://www.medworm.com/index.php?rid=3298275&cid=t_103336_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2010%2F02%2F23%2Faspirin-keeps-breast-cancer-at-bay%2F Filed under: Breast Cancer, Cancer SurvivorsBreast cancer survivors who took aspirin -- a baby aspirin or one adult pill -- after completing treatment were half as likely to die or have their tumors spread than those survivors who did not, according to a recent study published in the Journal of Clinical Oncology. According to study author Michelle Holmes, M.D., of Harvard Medical School and Brigham and Women's Hospital, aspirin may help control cancer by fighting inflammation. Cancers cells produce more inflammatory chemicals than normal breast cells. Of the women who were followed during the study, those who regularly took aspirin were 71 percent less likely to relapse with a deadly form of breast cancer than those who avoided the pain reliever. That's good news for the 2 million Amer... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=3298275 Tue, 23 Feb 2010 00:00:00 +0100 3298275 http://www.medworm.com/index.php?rid=3149114&cid=t_103336_109_f&fid=34750&url=http%3A%2F%2Fpsychcentral.com%2Fblog%2Farchives%2F2010%2F01%2F06%2Fplacebo-as-good-as-paxil-tofranil-for-most-depression%2F From the “What the…?!” file, new research we reported on today found that two antidepressants — Paxil (still commonly prescribed) and Tofranil (not commonly prescribed) — seem to only really work for the most severe kind of depression. When prescribed for mild to moderate — the vast majority of depression diagnosed today — these two antidepressants did not any better than a sugar pill placebo. The researchers for this new study pooled together the results of six previously published research studies that compared the effects of antidepressants to placebo for 718 adults with varying levels of depression — from very severe depression, to moderate depression, to mild depression. Three of the studies looked at paroxetine (Paxil) and the others l... World of Psychology blogs http://www.medworm.com/rss/comments.php?id=3149114 Wed, 06 Jan 2010 22:06:39 +0100 3149114 http://www.medworm.com/index.php?rid=2930999&cid=t_103336_101_f&fid=38969&url=http%3A%2F%2Ftheemtspot.com%2F2009%2F10%2F27%2Fare-all-aspirin-created-equal%2F “I took an Aspirin when I started feeling the pain.” Close to a decade after the Aspirin for chest pain idea hit the main-stream, more and more folks are medicated themselves at the onset of chest pain. But are all Aspirin created equal? Does chewing make any difference in the rate of absorption? No … and yes. A recent study out of the University of California, San Diego took 14 healthy volunteers and feed them a moderate dose of Aspirin on three separate occasions. First they were asked to swallow adult size tablets, then they were asked to chew adult sized tablets and last they were asked to chew children’s chewable Aspirin tablets. After each administration the volunteers had blood drawn at set intervals. The results were predictable, but telling. After swa... The EMT Spot blogs http://www.medworm.com/rss/comments.php?id=2930999 Tue, 27 Oct 2009 12:00:44 +0100 2930999 http://www.medworm.com/index.php?rid=2851801&cid=t_103336_105_f&fid=39005&url=http%3A%2F%2Fwww.allkidney.com%2F2009%2F09%2Fchronic-use-of-aspirinparacetamol-containing-drugs-and-chronic-kidney-disease.html photo credit: Wallula Junction Chronic use of over the counter pain killers have previously been cited as something to avoid if you have kidney disease. There is well established evidence that mixed analgesics have negative effects on kidney function. So much so that a specific disorder chronic analgesic nephropathy has been described. It has been defined as the renal damage that occurs when two analgesics and caffeine or another drug is taken routinely over years. You may ask yourself who would take such medication on a chronic basis? However many people with chronic disease particularly painful conditions for which there is no definitive therapy such as chronic osteoarthritis or nerve damage take these drugs for relief of chronic pain. Problems occur with dependence induced because of ... All Kidney News blogs http://www.medworm.com/rss/comments.php?id=2851801 Thu, 01 Oct 2009 01:12:18 +0100 2851801 http://www.medworm.com/index.php?rid=2757710&cid=t_103336_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D7814 I have seen local community forums where lay persons are advising others to take aspirin like “multivitamins” to prevent strokes and heart attacks. We do not have sound evidence for doing so in the healthy population. In fact indiscriminately popping low dose aspirin would probably result in seeing more bleeding complications. Recent research from Britain shows that Aspirin does more harm than good in healthy people At a conference for leading doctors, British scientists said they have found that for healthy people taking aspirin does not significantly reduce the risk of a heart attack. At the same time they found it almost doubles the risk of being admitted to hospital due to internal bleeding. The findings show that for otherwise healthy people the risks of taking aspirin ou... Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=2757710 Mon, 31 Aug 2009 23:00:00 +0100 2757710 http://www.medworm.com/index.php?rid=2751980&cid=t_103336_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FUQphnFTa97A%2F We’ve heard for years now that taking a daily dose of aspirin may help prevent heart attacks. Certainly, for those who have already had heart trouble, aspirin has proven to be a great benefit. But new research looked at healthy people who were taking aspirin as a precaution, and found that it may do more harm than good. Researchers have found that is a person is healthy, taking aspirin does not necessarily reduce the risk of having a future heart attack. More than that, however, daily aspirin use in healthy people may up the risk of internal bleeding at some point. This research clearly contradicts the advice to take an aspirin every day if you’re healthy. What should you do? Discuss the risks and benefits with your doctor. Aspirin may still be a good choice for you, but only ... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2751980 Mon, 31 Aug 2009 17:44:51 +0100 2751980 http://www.medworm.com/index.php?rid=2610867&cid=t_103336_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F07%2F16%2Fheart-2009-volume-95-no-15%2F Contents Page Title: Assessment of aspirin resistance varies on a temporal basis in patients with ischaemic heart disease Fade Skinny: Finds the prevalence of aspirin resistance is dependent on the method of testing. Response varies on a temporal basis, indicating that testing on a single occasion is inadequate to diagnose resistance or guide therapy in a clinical setting. (Requires NHS Athens Password for access) Posted in Access, Access from Home, Access from Work, Access in the Library, Athens Password, Current Awareness, E-Journals, Heart Diseases Tagged: Aspirin, Athens Password, Current Awareness, E-Journals, Heart Diseases (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2610867 Thu, 16 Jul 2009 14:01:57 +0100 2610867 http://www.medworm.com/index.php?rid=2561350&cid=t_103336_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FSOL1TA2liQY%2F Have a headache? Take a Tylenol or some other brand of acetamenophen, right? Howe about a toothache? Menstrual cramps? Broken arm? There are many types of over-the-counter pain relievers available to the consumer, namely acetaminophen, ibuprofen (Advil) and ASA (Aspirin). And, for many people, they’re very effective. The problem is, who is monitoring how much of these medications they take and how often? It must be safe! “I can buy it off the shelf, it’s got to be safe.” Sound familiar? That’s the way many people think about medications they can just walk in and buy. That’s not always the case. Yes, the medication itself is usually safe for most people if taken in the right way, but that leaves a lot of “ifs” in there, doesn’t it? A maj... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2561350 Wed, 01 Jul 2009 17:16:45 +0100 2561350 http://www.medworm.com/index.php?rid=2477512&cid=t_103336_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F06%2F15%2Farchives-of-neurology-volume-66-number-6%2F Contents Page Fade Fave: Use of Antithrombotic Drugs and the Presence of Cerebral Microbleeds: The Rotterdam Scan Study Fade Skinny: This cross-sectional study shows that use of platelet aggregation inhibitors is related to the presence of cerebral microbleeds. Furthermore, aspirin and carbasalate calcium use may differently relate to the presence of strictly lobar microbleeds. (NHS Athens is required to access this article online) Posted in Current Awareness Tagged: Aspirin, Athens Password, Current Awareness, E-Journals, Neurology (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2477512 Mon, 15 Jun 2009 08:37:05 +0100 2477512 http://www.medworm.com/index.php?rid=2441535&cid=t_103336_107_f&fid=36698&url=http%3A%2F%2Fminingdrugs.blogspot.com%2F2009%2F05%2Fdrug-popularity-via-google-queries-yet.html Here some drug popularity trends based on automatic Google queries. The drug names were taken from DrugBank.The top ten areCholesterolAspirinEthanolIbuprofenInsulinAcetaminophenTestosteroneCocaineOxycodoneVardenafilReferencesI used a Python script for the Google data fetching. Let me know, if you need more details.The Long Tail @WikipediaDrugBank: a knowledgebase for drugs, drug actions and drug targets. Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M.Nucleic Acids Res. 2008, 36, (Database issue):D901-6.PMID: 18048412DrugBank: a comprehensive resource for in silico drug discovery and exploration.Wishart DS, Knox C, Guo AC, Shrivastava S, Hassanali M, Stothard P, Chang Z, Woolsey J.Nucleic Acids Res. 2006, 34, (Database issue):D668-72. PMID: 16381955 (So... Mining Drug Space blogs http://www.medworm.com/rss/comments.php?id=2441535 Fri, 29 May 2009 22:09:00 +0100 2441535 http://www.medworm.com/index.php?rid=2405245&cid=t_103336_97_f&fid=35606&url=http%3A%2F%2Fwww.theangriestpharmacist.com%2F2009%2F05%2F14%2F7-to-10-of-the-10-things-your-pharmacist-wont-tell-you%2F The first part of this post containing number 1 to 6 can be found at: http://www.theangriestpharmacist.com/2009/05/12/1-to-6-of-10-things-your-pharmacist-wont-tell-you/ Let’s get back to ripping this bitch up… [The Article was originally published in "Smartmoney Magazine" on April 28th, 2009. No primary author was identified -- that was smart...otherwise I would be CALLING him/her.] Update: Their main source for information is a man named Larry Sasich of Pennsylvania. I visited the PA Board of Pharmacy and he is NOT a registered pharmacist in the state of PA. Way to verify your sources there Smartmoney.com — BTW, I’m sure he’s a nice man and very smart. You can’t be an idiot and make it to his position at what seems to be a very innovative, accredited  ... The Angriest Pharmacist blogs http://www.medworm.com/rss/comments.php?id=2405245 Thu, 14 May 2009 09:23:50 +0100 2405245 http://www.medworm.com/index.php?rid=2285061&cid=t_103336_97_f&fid=35606&url=http%3A%2F%2Fwww.theangriestpharmacist.com%2F2009%2F03%2F20%2Fstupid-patient-questions%2F This post will be dedicated to stupid patient questions. I will update it as more are submitted via comments and email. I would prefer to cite, link, and date them if able — so, please include that information if available. I’d like to limit these to those that HAPPENED TO YOU! Not a, “my friend told me he had the suppository unwrap thing happen.” -=+=- A father asks, with a very serious/concerned look, “Can my daughter eat Hot Cheetos with her Claritin prescription?” ~WAGBoy (March 09) “My mother is having a reaction to her Levaquin. I see on the warnings that she should not take this with calcium. Do you think I should give her some calcium to counteract the effects of the Levaquin?” ~Erin ( March 09) “My eye has been really irritated and... The Angriest Pharmacist blogs http://www.medworm.com/rss/comments.php?id=2285061 Sat, 21 Mar 2009 02:53:59 +0100 2285061 http://www.medworm.com/index.php?rid=2216627&cid=t_103336_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D6212 strWebsiteID = window.document.location.toString();strSplitWeb = strWebsiteID.split("/")strWebsiteID = strSplitWeb[2];document.write(”“); from the Malaysian Medical Resources VIDEO: Drinking Soda May Increase Kidney Damage in Women, Urine Test Studied for Prostate Cancer Detection, Daily Aspirin May Reduce Colon Polyp Risk (Source: Malaysian Medical Resources) Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=2216627 Tue, 24 Feb 2009 05:00:00 +0100 2216627 http://www.medworm.com/index.php?rid=2134858&cid=t_103336_134_f&fid=36049&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FDiabetesNotes%2F%7E3%2Fi42VdiOBM0M%2F var iamInit = function() {try{initIamServingHandler(320,212,536684,"http://cdn.pis.picapp.com/IamProd/Resources/Css/css2.css")}catch(ex){}}() Have you heard the thought that aspirin, specifically anti-inflammatory aspirin, is helpful in preventing diabetes? Well researchers took this same concept and applied it to low-dose aspirin. The result? That low-dose aspirin, while having many other healthful benefits, does not help prevent Type 2 diabetes. David S. H. Bell, MD, an Endocrine Today Editorial Board member, said: “This finding is not surprising since low dose aspirin was utilized. High dose aspirin or other salicylates, which are truly anti-inflammatory, have been shown to decrease insulin resistance and perhaps improve beta cell function. Clinical trials to evaluate the effect... Diabetes Notes blogs http://www.medworm.com/rss/comments.php?id=2134858 Mon, 26 Jan 2009 14:38:03 +0100 2134858 http://www.medworm.com/index.php?rid=2074611&cid=t_103336_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FAp5DYSTpTWQ%2F Before you start any drug regiment, make sure to ask your health care provider first. This is even more important if you have any health issues. Some over the counter drugs can cause problems for a number of people, especially those with heart problems and high blood pressure. Not everyone can take an aspirin daily due to the fact some people are resistant to them. Women have proven to be more likely to be resistant to the blood-thinning effects of aspirin. An aspirin daily is used by millions of people to prevent heart attacks. The aspirin breaks up platelets in the blood that could eventually form blood clots. I found this information on the CNN health, click on the CNN site to view more information.  Tags: aspirin, blood clots, heart-attack, high-blood-pressureShare This (So... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2074611 Tue, 30 Dec 2008 15:00:35 +0100 2074611 http://www.medworm.com/index.php?rid=1952312&cid=t_103336_134_f&fid=36049&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FDiabetesNotes%2F%7E3%2FzYiU7duedzU%2F var iamInit = function() {try{initIamServingHandler(420,280,257067,"http://cdn.pis.picapp.com/IamProd/Resources/Css/css2.css")}catch(ex){}}() According to BD Diabetes: “Doctors should not routinely give aspirin to people with diabetes to help guard against a heart attack or stroke, researchers conclude based on a study they conducted. While it was effective for those who had already developed heart disease or suffered a stroke, regular aspirin offered no benefit for patients with diabetes and a common circulatory problem, researchers said.” However, if you’ve already had a stroke or heart disease, aspirin remains an effective treatment. Tags: aspirin, Diabetes, diabetics, findings, heart-disease, prevention, Research, stroke, studyShare This (Source: Diabetes Notes) Diabetes Notes blogs http://www.medworm.com/rss/comments.php?id=1952312 Wed, 12 Nov 2008 13:55:44 +0100 1952312 http://www.medworm.com/index.php?rid=1948504&cid=t_103336_167_f&fid=37833&url=http%3A%2F%2Fnutrition.edublogs.org%2F2008%2F10%2F30%2Faspirin-101%2F Estimates figure that about 60 percent of people ages 65 and older take an aspirin at least once a week, some on the recommendation of their doctor (to prevent heart disease) some now. This common, over-the-counter medication can cause some serious side effects. Regular use should be discussed with a doctor. Aspirin is routinely recommended by the American Heart Association for people who’ve had a heart attack, stroke caused by blood clot, unstable angina, or “ministrokes.” Further more the American Heart Association recommends that people who have yet to experience an event but who are at increased risk because of family history, say, may also stand to gain from aspirin therapy. Here are some things you may not know about Aspirin. 1. Aspirin would have a hard time gettin... Nutrition and Wellness Biology 50 blogs http://www.medworm.com/rss/comments.php?id=1948504 Thu, 30 Oct 2008 22:41:38 +0100 1948504 http://www.medworm.com/index.php?rid=1948505&cid=t_103336_167_f&fid=37833&url=http%3A%2F%2Fnutrition.edublogs.org%2F2008%2F10%2F29%2Ftruth-in-advertising-bayer-warned-aspirin-claims%2F According to Federal regulators from the Food and Drug Administration, Bayer has been illegally marketing two aspirin products that make unsubstantiated health claims about fighting heart disease and osteoporosis. In both cases, the aspirin has been combined with a dietary supplement into a single pill. Aspirin is often recommended by doctors to treat general aches and pains and in small doses (baby aspirin) as a blood thinner for patients with heart disease. The two products in question: Bayer Aspirin with Heart Advantage (Bayer Heart Advantage)–aspirin combined with phytosterols (a plant-based supplement also known as plant sterols) Bayer Women’s Low Dose Aspirin + Calcium (Bayer Women’s)–aspirin combined with calcium These product formulations are not approved by FDA. ... Nutrition and Wellness Biology 50 blogs http://www.medworm.com/rss/comments.php?id=1948505 Wed, 29 Oct 2008 21:49:11 +0100 1948505 http://www.medworm.com/index.php?rid=1918199&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F434839486%2F The agency sent a pair of warning letters to Bayer HealthCare concerning what it calls two “unlawful,” over-the-counter aspirin products — Bayer Women’s Low Dose Aspirin + Calcium (Bayer Women’s) and Bayer Aspirin with Heart Advantage (Bayer Heart Advantage). Here is letter one and letter two. The products, which contain aspirin with either phytosterols or calcium, are unapproved new drugs that require an approved new drug application in order to be legally marketed, according to an FDA statement. In addition to being labeled for use as a pain reliever, both products are labeled for use in reducing the risks of heart disease. Bayer Women’s is also labeled for use in “fighting” osteoporosis. However, the FDA says that “neither product has b... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1918199 Tue, 28 Oct 2008 15:56:20 +0100 1918199 http://www.medworm.com/index.php?rid=1888136&cid=t_103336_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D4942 This study also showed that antioxidant use was also not beneficial in the primary prevention of cardiovascular events in diabetics. a Routine aspirin use questionable in diabetics (Source: Malaysian Medical Resources) Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=1888136 Fri, 17 Oct 2008 04:00:00 +0100 1888136 http://www.medworm.com/index.php?rid=1880157&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F420811435%2F As part of its ongoing investigation into direct-to-consumer advertising, the House Energy & Commerce Committee is exploring two new lines of inquiry - why Bayer ignored FDA recommendations to refrain from marketing a version of its aspirin that is also a dietary supplement, and why the FDA hired a public relations firm that works for pharma to develop a consumer web site. The committee wants to know why Bayer promoted its Bayer Aspirin with Heart Advantage as safe and effective, when the FDA had warned against marketing such a combo. The tablet combines aspirin with a supplement Bayer claims can lower cholesterol. The FDA, however, only regulates the drug. In a letter to Bayer Healthcare prez Gary Balkema, committee chairman John Dingell and Bart Stupak, who heads the Oversight and I... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1880157 Tue, 14 Oct 2008 19:05:52 +0100 1880157 http://www.medworm.com/index.php?rid=1733978&cid=t_103336_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D4217 Looks like there is no end to this “universal” aspirin recommendation controversy. It’s not controversial in people at risk e.g. previous AMI, ischaemic stroke But for otherwise healthy people? There are more important lifestyle adjustments like diet, exercise, smoking cessation that one should entertain. I’ve just recently seen two elderly patients with potentially fatal upper GI bleed from aspirin ingestion and I fear that if everyone pops an aspirin every day, we’ll be seeing more. Of course you may argue that an individual doctor’s view is biased as he sees more things which go wrong. However I would also argue that not all populations are the same so we should not extrapolate one study and blindly apply it here without proper evidence. a An As... Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=1733978 Tue, 26 Aug 2008 04:00:00 +0100 1733978 http://www.medworm.com/index.php?rid=1709157&cid=t_103336_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D4109 Prehospital treatment with tirofiban plus standard anti-platelet therapy improves clinical outcomes in patients with ST-elevation myocardial infarction (STEMI), according to research published in The Lancet Looks like just getting aspirin in at the first signs of a heart attack is not enough! a Tirofiban Plus Standard Anti-Platelet Therapy Beneficial for STEMI Patients (Source: Malaysian Medical Resources) Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=1709157 Fri, 15 Aug 2008 04:00:00 +0100 1709157 http://www.medworm.com/index.php?rid=1700781&cid=t_103336_122_f&fid=35055&url=http%3A%2F%2Fsarasotaneurology.com%2F2008%2F08%2F12%2Foccipital-neuralgia-many-symptoms-of-headaches%2F Occipital neuralgia is a commonly missed headache diagnosis. The symptoms for headaches can be quite different. Occipital neuralgia can mimic migraine headaches but do not respond to standard migraine medications. Occipital neuralgia rarely occurs as a headache syndrome by itself. The majority of patients with occipital neuralgia have one or more other types of headache including: migraines, tension headache, rebound headache and cluster headaches. Occipital neuralgia is frequently misdiagnosed as migraine or cluster headaches. Patients with prominent face pain as part of their occipital neuralgia may be incorrectly diagnosed with tic delaroux (trigeminal neuralgia.) Occipital neuralgia is caused by an irritation of the occipital nerve as is comes through the muscles in the back of the nec... Sarasota Neurology blogs http://www.medworm.com/rss/comments.php?id=1700781 Tue, 12 Aug 2008 14:42:53 +0100 1700781 http://www.medworm.com/index.php?rid=2725088&cid=t_103336_122_f&fid=35055&url=http%3A%2F%2Fsarasotaneurology.com%2F2008%2F08%2F12%2Foccipital-neuralgia-many-symptoms-of-headaches%2F Occipital neuralgia is a commonly missed headache diagnosis. The symptoms for headaches can be quite different. Occipital neuralgia can mimic migraine headaches but do not respond to standard migraine medications. Occipital neuralgia rarely occurs as a headache syndrome by itself. The majority of patients with occipital neuralgia have one or more other types of headache including: migraines, tension headache, rebound headache and cluster headaches. Occipital neuralgia is frequently misdiagnosed as migraine or cluster headaches. Patients with prominent face pain as part of their occipital neuralgia may be incorrectly diagnosed with tic delaroux (trigeminal neuralgia.) Occipital neuralgia is caused by an irritation of the occipital nerve as is comes through the muscles in the back of the nec... Sarasota Neurology blogs http://www.medworm.com/rss/comments.php?id=2725088 Tue, 12 Aug 2008 13:43:17 +0100 2725088 http://www.medworm.com/index.php?rid=1689049&cid=t_103336_122_f&fid=35055&url=http%3A%2F%2Fsarasotaneurology.com%2F2008%2F08%2F07%2Fhealth-benefits-from-omega-3-fish-oil%2F There are many studies that have shown excellent health benefits from taking omega 3 type fish oil. Omega 3 oils are found in fish oils, flax seed and several vegetable oils including canola, soybean and olive oils. There are different components to these oils that provide health benefits. The DHA and EPA oils in fish oil have been linked to reducing hardening of the arteries and lowering triglycerides. They also have the benefit of lowering blood pressure and heart rate to a mild degree. This all results in an overall reduction in risk for coronary artery disease, heart attack, sudden death, irregular heart beat and stroke. Fish oil can also have a blood thinning effect to reduce abnormal blood clotting, similar to that of aspirin. This latter effect is a two edge sword because too much f... Sarasota Neurology blogs http://www.medworm.com/rss/comments.php?id=1689049 Thu, 07 Aug 2008 13:19:26 +0100 1689049 http://www.medworm.com/index.php?rid=1475415&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F300062809%2F The drugmaker was fined for fixing the price of aspirin and other over-the-counter medications in Germany, the Associated Press reported. Bayer Vital, a subsidiary, made illegal deals with more than half of Germany’s 21,000 pharmacies, according to Germany’s cartel office. Bayer offered rebates for the sale of its products at a certain price. In a statement, the Bayer unit declared that “Bayer Vital does not agree with the legal position” of the cartel office, but agreed to pay the fine in order to avoid a protracted legal fight. Since 2004, German pharmacies have been allowed to set their own prices for nonprescription medication. While pharmacies are allowed to offer reduced prices for shorter terms, long-term agreements are against the law. (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1475415 Wed, 28 May 2008 20:07:05 +0100 1475415 http://www.medworm.com/index.php?rid=1419140&cid=t_103336_134_f&fid=36049&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FDiabetesNotes%2F%7E3%2F282985839%2F Aspirin has been around forever and is still a miracle drug of sorts. What is one of our first lines of defense when people infarct? Four baby aspirin. What do we use to help prevent stroke? Aspirin. And now aspirin-like compounds can claim yet another huge health benefit- increasing the amount of insulin produced by ‘healthy’ obese people. This is a very promising discovery towards treating type 2 diabetes. The researchers found that administration of triflusal led to decreased fasting serum glucose. Contrary to their expectations, insulin sensitivity did not significantly change during the trial. Insulin secretion, however, significantly increased in relation to the dose size. In conjunction with the human samples, mice and human cells from a lab setting were also examined. ... Diabetes Notes blogs http://www.medworm.com/rss/comments.php?id=1419140 Sat, 03 May 2008 23:10:19 +0100 1419140 http://www.medworm.com/index.php?rid=1316753&cid=t_103336_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F254914457%2F A new group of aspirin type substances have been developed in Italy. Physicians know that a low daily dose of aspirin, or acetylsalicylic acid, reduces the risk of heart attacks and strokes in some, but we also know that aspirin causes an upset belly as well. A safer form of aspirin is needed and that is exactly what these researchers have set out to accomplish. In the new study, Alberto Gasco and colleagues designed a new form of aspirin by attaching a special chemical structure — called a nitrooxy-acyl group — that allows the drug to resist breakdown by stomach acidity while promoting its absorption by the blood. The results were positive among the mice that were used.  Time will tell, but I am in hopes for this to pan out! via American Chemical Society  Tags: aspirin, bloo... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=1316753 Thu, 20 Mar 2008 13:34:08 +0100 1316753 http://www.medworm.com/index.php?rid=1314061&cid=t_103336_87_f&fid=34595&url=http%3A%2F%2Fnhsblogdoc.blogspot.com%2F2008%2F03%2Fcrippen-diaries-2008-march-3.html What do you want to do when you grow up...March 2008 (3)The sad news that Terry Pratchett has, at the relatively young age of 59, been diagnosed as suffering from an unusual form of Alzehimer’s has understandably caused yet more concern about this wretched disease. Terry has coined a delightful neologism. He calls it an “embuggerance”.It seems only yesterday that we were all worried about BSE and frantically trying to avoid hamburgers and British meat. That fad is now long forgotten. Is British meat now any safer than it was before? I haven’t a clue. They never had BSE in the USA. American meat was always safe. Of course it was. They would have told us if it had not been. You can believe that if you want to.Yesterday, I saw a 77 year old lady. We will call her Enid. She is a widow.... NHS Blog Doctor blogs http://www.medworm.com/rss/comments.php?id=1314061 Wed, 19 Mar 2008 11:54:00 +0100 1314061 http://www.medworm.com/index.php?rid=1288469&cid=t_103336_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F247918482%2F What dose of Aspirin do you take? enteric coated 325 mg baby asa 81 mg different dose per my doctor I do not take aspirin Add an Answer View Results Tags: aspirin, blood thinner, cardiac disease, heart diseaeShare This (Source: A Hearty Life) A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=1288469 Sat, 08 Mar 2008 14:29:39 +0100 1288469 http://www.medworm.com/index.php?rid=1268660&cid=t_103336_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F243261697%2F Vitamin D has the potential to become the “new aspirin“, the little inexpensive pill that may be able to block the development of some cancers, strengthen bones, prevent multiple sclerosis and alleviate winter depression. Such were the findings of a new Canadian study: But it’s not science fiction. The “new aspirin” could be Vitamin D. Just as we discovered that aspirin can guard against heart disease, Vitamin D could become a useful weapon in the fight against MS, osteoporosis, mild depression and one of the most devastating diseases of our time – cancer. “As time has gone by, Vitamin D has raised its head as a sort of ambrosia for cancers,” says Dr. Louise Parker, an epidemiologist and a world expert in the environmental exposures that can lead to cancer. Or, in t... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=1268660 Fri, 29 Feb 2008 11:17:14 +0100 1268660 http://www.medworm.com/index.php?rid=1187255&cid=t_103336_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F225558102%2F Before it was an aspirin a day keeps the heart doctor away. Now, according to a study published in Gastroenterology (the official journal of the American Gastroenterological Association (AGA) Institute), the use of regular, long-term aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) reduces the risk associated with colorectal cancer. According to Andrew T. Chan, MD, MPH, Massachusetts General Hospital and lead author of the study: “While the results of our study show that aspirin should not currently be recommended for the chemoprevention of colorectal cancer in a healthy population, there is a need for further studies to help identify for which patients the potential benefits outweigh the risks. We also need to improve our understanding of how aspirin works to prevent and i... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=1187255 Wed, 30 Jan 2008 00:00:10 +0100 1187255 http://www.medworm.com/index.php?rid=1128883&cid=t_103336_117_f&fid=36026&url=http%3A%2F%2Fblog.healthtalk.com%2Fzimney%2Faspirin-may-interfere-with-treatment-for-advanced-prostate-cancer%2F If you or someone you love has advanced prostate cancer and is receiving hormone treatments, it may not be wise also to be taking aspirin. That’s because of recent findings that show that for some men the aspirin, which is commonly used in low daily doses for prevention of heart attack and stroke, may result in liver toxicity, which shows itself as elevations in liver enzymes on blood tests. While this liver toxicity might not be that significant in and of itself, in men who are receiving hormone treatment for their prostate cancer with the antiandrogen drug Eulexin (flutamide), any sign of liver injury will result in its immediate discontinuation because of its known potential to cause serious liver toxicity. The problem is that it might be the aspirin that’s causing the elevated live... Dr. Z's Medical Report blogs http://www.medworm.com/rss/comments.php?id=1128883 Thu, 03 Jan 2008 18:45:37 +0100 1128883 http://www.medworm.com/index.php?rid=1022141&cid=t_103336_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F11%2F13%2Fh-pylori-and-humans-an-ambivalent-relationship.html  By Dov Michaeli MD, Ph.D Several months ago I received an alarming phone call from my nephew: he had terrific pain in his abdomen which caused him to double over. His stool was pitch black. It was obvious that he had an acute stomach ulcer, probably bleeding. What could cause this painful disease?Since the late 19th century doctors described the existence of bacteria in the stomach, but for a variety of reasons these reports did not gain traction, or were simply not believed. The bacterium, later named Helicobacter pylori was rediscovered in 1979 by Australian pathologist Robin Warren, who did further research on it with Barry Marshall beginning in 1981; they isolated the organisms from mucosal specimens from human stomachs and were the first to successfully cultu... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=1022141 Tue, 13 Nov 2007 07:21:20 +0100 1022141 http://www.medworm.com/index.php?rid=968377&cid=t_103336_122_f&fid=35055&url=http%3A%2F%2Fsarasotaneurology.com%2F2007%2F10%2F22%2Fstroke-prevention-a-better-way-of-stroke-treatment%2F The objective is to have a total cholesterol less than 180, good cholesterol (HDL) of greater than 50 and bad cholesterol (LDL) less than 100. A recent study published in the journal Stroke reported that discontinuing statin therapy in the year after a stroke is associated with a significant increase in the risk for death, even in the absence of heart disease. Medications are not the only treatment for stroke prevention. Smoking is associated with a 2-3 times greater risk of stroke and bleeding in the brain. Smoking also contributes to the accelerated development of heart disease, emphysema and peripheral artery disease. Chantix is a new medication that received FDA approval to help stop smoking. Exercise is important in maintaining overall body conditioning and weight control. This in tur... Sarasota Neurology blogs http://www.medworm.com/rss/comments.php?id=968377 Mon, 22 Oct 2007 11:15:34 +0100 968377 http://www.medworm.com/index.php?rid=945310&cid=t_103336_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F10%2F12%2Fstress-the-silent-killer.html Conclusion On the biological level, this is yet another demonstration of the mind-body relationship. In fact, a whole field of research called psychoneuroimmunology (I know, it’s a mouthful, but if you break it up to its component words, psycho-neuro-immunology, it makes sense) is thriving and is uncovering new connections between brain, mind and immune response on an almost daily basis. On the clinical level, the strengthening evidence of the effect of stress on health and disease suggests new modalities and approaches to treatment. What is most intriguing and potentially far-reaching, are the societal consequences. Now that we accrue more and more evidence on the effects of stress on health, it would make economic sense to pay attention to the work environment. An enlightened manag... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=945310 Fri, 12 Oct 2007 05:29:39 +0100 945310 http://www.medworm.com/index.php?rid=941987&cid=t_103336_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F168048188%2F Germany’s antitrust agency has launched an investigation into the German drugmaker for reportedly conspiring with some 11,000 pharmacies to artifically inflate the price of its popular aspirin. The probe was first reported by Stern magazine and later confirmed by the agency. Bayer allegedly offered to sell the painkiller to pharmacies for a discount of up to 3 percent if, in return, the pharmacies agreed to put the pill on sale in their store for only up to four weeks - and for a price reduction of no more than 20 percent. “We are investigating the accusations,” says Silke Kaul, a spokeswoman for the antitrust agency. A Bayer spokesman denies the allegations. “There has been no illegal price-fixing,” sniffs Hartmut Alsfasser, adding that Bayer had contacted th... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=941987 Wed, 10 Oct 2007 18:22:02 +0100 941987 http://www.medworm.com/index.php?rid=928758&cid=t_103336_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F10%2F5%2Fthe-age-of-individual-medicine-is-dawning.html  By Dov Michaeli MD, Ph.DHere is some exciting news from the Biotech world: the time is fast approaching when your personal DNA sequence will be readily available. So what’s the big deal? Read on.The human genome projectIn 2003, the first complete genetic blueprint was published with great fanfare (President Bush, believe it or not, was present at the announcement). At the time, scientific pundits, journalists, and self-appointed crystal ball-gazers, fell over each other proclaiming the benefits of this scientific feat. Indeed, the possibilities were, and still are, simply huge. People expected the advances to come tumbling down almost immediately; it did not happen. Why? Money! It cost about 3 billion dollars to complete the first sequencing in 2003. At that price, it would hav... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=928758 Fri, 05 Oct 2007 06:10:13 +0100 928758 http://www.medworm.com/index.php?rid=886425&cid=t_103336_109_f&fid=35671&url=http%3A%2F%2Fwww.anxietyinsights.info%2Fabstract_aspirin_lowers_acute_stressinduced_atherothrombot.htm Brain Behav Immun. 2007;doi:10.1016/j.bbi.2007.07.005 Aspirin, but not propranolol, attenuates the acute stress-induced increase in circulating levels of interleukin-6: A randomized, double-blind, placebo-controlled study von Känel R, Kudielka BM, Metzenthin P, Helfricht S, Preckel D, Haeberli A, Stutze M, Fischer JE. Department of General Internal Medicine, University Hospital Bern, CH-3010 Bern, Switzerland; Psychocardiology Unit, Cardiac Prevention and Rehabilitation, Swiss Cardiovascular Center University Hospital Bern, Bern, Switzerland; Department of Theoretical and Clinical Psychobiology, University of Trier, Trier, Germany; Faculty of Health, Bern University of Applied Sciences, Bern, Switzerland; Department of Clinical Research, University Hospital Bern, Bern, Switzerland; De... Latest entries from www.anxietyinsights.info blogs http://www.medworm.com/rss/comments.php?id=886425 Thu, 20 Sep 2007 08:27:00 +0100 886425 http://www.medworm.com/index.php?rid=733633&cid=t_103336_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F07%2F13%2Farthritis-drug-could-prevent-diabetes%2F Filed under: Type 2, Drugs, ResearchA major study of patients with rheumatoid arthritis (RA) is just out. It found that those treated with hydroxychloroquine (HCQ) - brand name: Plaquenil - an antimalarial drug also prescribed for RA, are much less likely to develop Type 2 diabetes. The study was conducted over a period of more than twenty years and analyzed the treatment of 4,905 adult patients with RA. Bottom line: relative risk for T2 diabetes declined by up to seventy-seven percent in patients who took HCQ for four years. Wow. But that's not all. The researchers also say the RA patient who did develop diabetes were less likely to need medications for blood sugar control. Moreover, according to Mary Chester M. Wasko, a rheumatologist and professor of medicine at the University of Pittsb... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=733633 Fri, 13 Jul 2007 04:00:00 +0100 733633 http://www.medworm.com/index.php?rid=698081&cid=t_103336_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F6%2F26%2Fthe-aspirin-dilemma-to-take-or-not-to-take.html A recent study from the Mayo Clinic, published in the Journal of the National Cancer Institute (JNCI, vol. 99, p. 825, 2007), looks at the relationship between the use of aspirin and non-aspirin NSAID (non steroidal anti inflammatory drugs) in postmenopausal women and the incidence of death from cancer, heart disease, and death from any cause.  How the study was done The investigators studied data on about 22,500 women who were enrolled in the Iowa Women's Health Study, a long-term health study of women living in Iowa. Starting in 1986, the women completed surveys periodically about their medical history, diet, physical activity, smoking, and other factors every year until 1992. In that year, the women also reported their use of aspirin and nonaspirin nonsteroidal anti-... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=698081 Tue, 26 Jun 2007 03:31:13 +0100 698081 http://www.medworm.com/index.php?rid=650911&cid=t_103336_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F05%2F31%2Fmedications-that-cause-high-blood-sugar%2F Filed under: Type 1, Type 2, Childhood, Adult Onset, Drugs, Research, SupportSeveral commonly used drugs have adverse effects on glucose metabolism. Among these drugs are: aspirin, and an antibiotic. Aspirin is a commonly used drug to relieve minor aches and pains, to reduce fever, as an anti-inflammatory and as a blood-thinner. However, studies show it leads to glucose metabolism impairment in insulin-sensitive tissues. A 3g daily dose of aspirin was administered over a three-day period. Although insulin release increased after the aspirin, the glucose remained unchanged. Despite the increased insulin, the body seemed to decrease cellular sensitivity to insulin in the aftermath of aspirin. A healthcare facility in Scottsdale, AZ advises doctors to avoid giving gatifloxacin to patients wit... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=650911 Thu, 31 May 2007 04:00:00 +0100 650911 http://www.medworm.com/index.php?rid=612085&cid=t_103336_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F05%2F15%2Fregular-vs-baby-aspirin-which-to-take%2F Filed under: Prevention, ResearchIf you're swallowing an aspirin a day, are you taking a regular or baby aspirin? If you're taking a regular dose, it may be time to discuss it with your doctor. A recent research review found that baby aspirin does the job preventing clots and that the higher dose pill may not be more effective. What a higher dose does do is increase the risk of developing bleeding of the stomach or intestines, and taking a baby aspirin may reduce that risk.Don't change your aspirin dose on your own, however. Though the research seems to indicate that a baby aspirin is plenty, the jury's still out on whether a higher dose aspirin may be more appropriate for certain people.Read | Permalink | Email this | Linking Blogs | Comments (... The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=612085 Tue, 15 May 2007 04:00:00 +0100 612085 http://www.medworm.com/index.php?rid=604128&cid=t_103336_97_f&fid=35050&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmaGazette%2F%7E3%2F115620626%2Finteresting_finds_pharmarelate_7.html Check out the following great posts from the blogosphere that I think would interest pharma business readers as well: Centrally Active ACE inhibitors May Help Reduce Risk of Cognitive Decline in Older Adults Twinject, Now With Enhanced Features Diabetes Drug Avandia® (rosiglitazone maleate) Boosts Potency of Platinum Chemotherapy Curecumin™ Could be an Effective Treatment for Skin Cancer Aspirin Resistance Growing Concern for Cardiovascular PatientsLink Between Tamiflu and Abnormal Behavior - Still Confusing?Enjoy, have a great read! (Source: PharmaGazette) PharmaGazette blogs http://www.medworm.com/rss/comments.php?id=604128 Thu, 10 May 2007 14:57:24 +0100 604128 http://www.medworm.com/index.php?rid=566393&cid=t_103336_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F04%2F24%2Faspirin-overlooked-for-heart-health%2F Filed under: Prevention, ResearchA few weeks ago I posted something on TheDiabetesBlog related to the use of aspirin. Researchers found it to be insufficient in helping blood flow in people with diabetes. For people who do not have diabetes, however, aspirin is a known combatant against heart attack and stroke -- yet only 41 percent of Americans over the age of 40 regularly take it. Researchers involved in the study, which will be published in the May issue of the American Journal of Preventative Medicine, were admittedly surprised to find that such a low percentage of aspirin users. Stephen Wesimana, PhD, one of the lead researchers in the study, stated "We expected to see greater than 70% utilization rates." Aspirin should not be taken by everyone, particularly by people who are allergic... The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=566393 Tue, 24 Apr 2007 04:00:00 +0100 566393 http://www.medworm.com/index.php?rid=563662&cid=t_103336_97_f&fid=35050&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmaGazette%2F%7E3%2F111170992%2Finteresting_finds_pharmarelate_5.html Dear readers, I hope you’ve enjoyed your weekend. With your nightcap, let me direct you to great posts from my immediate blogosphere: Allergizer: Tropicana® Healthy Heart with Omega-3: Not For the Fish Allergic Cancer Commentary: Long Term Daily Dose of Adult-Strength Aspirin = Reduced Cancer Risk? Straight From The Doc: Sugar Substitute Aspartame is No Carcinogen, FDA Says Well Woman Blog: The Truth About Birth Control Pills Well it seems the blogosphere never sleeps, even on a fine weekend! Have a great read. (Source: PharmaGazette) PharmaGazette blogs http://www.medworm.com/rss/comments.php?id=563662 Mon, 23 Apr 2007 03:11:43 +0100 563662 http://www.medworm.com/index.php?rid=525556&cid=t_103336_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F04%2F06%2Fibuprofen-reduces-blood-thinning-effects-of-aspirin%2F Filed under: Prevention, ResearchThe first randomized trial evidence revealing the dangers of taking ibuprofen and aspirin together was recently released by the Mount Sinai School of Medicine. The research suggests that the ibuprofen inhibits the blood thinning properties of aspirin, leaving patients at a reported nine-times higher risk of heart attack. The cardiovascular health of 18,523 patients who are over 50 years old and had osteoarthritis (which is why they were likely taking the ibuprofen) was reviewed by the researchers involved with this study. The researchers concluded that doctors should seriously reconsider ever giving patients, who are at risk of cardiovascular problems, ibuprofen to deal with pain.Read | Permalink | Email this | Linking Blo... The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=525556 Fri, 06 Apr 2007 04:00:00 +0100 525556 http://www.medworm.com/index.php?rid=522062&cid=t_103336_97_f&fid=35050&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmaGazette%2F%7E3%2F106752080%2Fof_christs_passion_holiday_tem.html It is already Maundy Thursday here in the Philippines. In observance of Semana Santa (Holy Week) in a Catholic country like ours, Maundy Thursday until Easter Sunday is a National Holiday. Offices and business, commercial establishments are mostly closed and even if not all are in observance of the Passion of Christ, almost everyone around me is on vacation mode: people in fact take this opportunity to be home with their families.Unfortunately (or fortunately!) this year, Easter Monday (April 9) is National Heroes’ Day, another official holiday: making the already long weekend even longer. (Yes, we are one of those countries in the world with the most national holidays in a year.) For a full time problogger like me when everyday is mostly business as usual, it is very difficult ... PharmaGazette blogs http://www.medworm.com/rss/comments.php?id=522062 Thu, 05 Apr 2007 04:35:32 +0100 522062 http://www.medworm.com/index.php?rid=521805&cid=t_103336_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F04%2F04%2Faspirinsufficient%2F Filed under: Type 1, Type 2, ResearchYou hear it from your doctors. You hear it from your friends and relatives. You hear it on TV. You hear it, well, all the time: Aspirin can help prevent future heart attacks. You hear it for good reason, because it does. That is, unless you are a person with diabetes. Researchers from the Sianai Hospital of Baltimore recently demonstrated that the standard dose of aspirin may not provide adequate protection against future heart attack. Studying 120 aspirin treated patients -- 30 of which had diabetes -- with stable coronary artery disease, the researchers discovered that diabetic patients showed a greater proclivity to aspirin resistance than non-diabetic patients. This does not mean that aspirin cannot help people with diabetes in preventing future he... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=521805 Wed, 04 Apr 2007 04:00:00 +0100 521805 http://www.medworm.com/index.php?rid=479947&cid=t_103336_130_f&fid=34941&url=http%3A%2F%2Forthosportsrehab.blogspot.com%2F2007%2F03%2Fcaution-for-aspirin-users.html Not to deviate much from the sports/orthopaedic focus of this blog, but I came across another article on the caution for patients taking Aspirin. We posted last week on the American Heart Association's new guidelines which encourages physicians to limit drug therapy for pain, especially NSAIDs. Today there was a new report that people at average risk for colon cancer should not take aspirin or ibuprofen and similar painkillers to try to prevent the disease because of the risk of developing bleeding and other problems. Just something else to think about regarding patient care in states with direct access to physical therapy services.Washington PostTuesday, March 6, 2007; Page A08Aspirin Taken as Cancer Preventative Has Risks Save This Page (Source: Concepts in Orthopaedic and Sports Medicin... Concepts in Orthopaedic and Sports Medicine Rehab blogs http://www.medworm.com/rss/comments.php?id=479947 Wed, 14 Mar 2007 23:41:00 +0100 479947 http://www.medworm.com/index.php?rid=486634&cid=t_103336_87_f&fid=35047&url=http%3A%2F%2Fwww.ideasforwomen.com%2Fnews%2Fwomens-health%2F2007%2F02%2F20%2F119%2F (I’ve been having ergonomic problems again and have not been able to post too much.) The American Heart Association just released new guidelines for women to help prevent cardiovascular disease. The emphasis of the updated guidelines is on long term, lifetime risk reduction not just short term reduction. The recommendations include the reduction of alcohol consumption and sodium intake, controling weight and increasing physical activity. The physical activity levels recommended for women trying to lose weight or keep it off are to exercise at an intensity level to that of brisk walking for a minimum of 60 to 90 minutes a day - everyday! While I don’t doubt that that is a good idea I do doubt that most women would have time for that. After working 8+ hours a day, driving back a... Ideas For Women News Blog blogs http://www.medworm.com/rss/comments.php?id=486634 Tue, 20 Feb 2007 19:20:55 +0100 486634