MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'biomarker'. Sat, 03 Sep 2011 02:01:27 +0100 http://www.medworm.com/index.php?rid=5140182&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2011%2F08%2F18%2Fmesothelin-antibodies-occur-in-some-women-with-an-epidemiologic-risk-for-ovarian-cancer%2F Researchers at Rush University Medical Center discover mesothelin antibodies in the bloodstream of infertile women, who possess a higher risk of ovarian cancer. Using a new approach to developing biomarkers for the very early detection of ovarian cancer, researchers at Rush University Medical Center have identified a molecule in the bloodstream of infertile women, who [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=5140182 Thu, 18 Aug 2011 16:32:48 +0100 5140182 http://www.medworm.com/index.php?rid=4841885&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2011%2F05%2F19%2Fasco-2011-genetic-biomarker-predicts-taxane-drug-induced-neuropathy%2F A new study has identified the first genetic biomarkers for taxane-induced peripheral neuropathy, a potentially severe complication of taxane chemotherapy that affects nerves in about one-third of patients with cancer receiving such treatment. ASCO Releases Studies From Upcoming Annual Meeting – Important Advances in Targeted Therapies, Screening, and Personalized Medicine The American Society of Clinical Oncology (ASCO) today highlighted [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=4841885 Thu, 19 May 2011 23:39:33 +0100 4841885 http://www.medworm.com/index.php?rid=4592642&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2011%2F03%2F15%2F2011-nccn-conference-new-treatment-options-lead-to-steady-progress-against-ovarian-cancer%2F Recommendations stemming from recent clinical trials highlight notable updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines™) for Ovarian Cancer at the National Comprehensive Cancer Network® (NCCN®) 16th Annual Conference. Although finding effective screening tools remains a priority, new treatment options for women with ovarian cancer, such as the ones outlined in the [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=4592642 Wed, 16 Mar 2011 01:20:30 +0100 4592642 http://www.medworm.com/index.php?rid=4360981&cid=t_110280_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fovarian-cancer-screening-is-still-subpar%2F2011.01.17 Cancer of the ovary is a particularly nasty disease. It often remains asymptomatic until it has reached an advanced, incurable stage, and scientists have been unable to develop an effective screening test for the disease like the ones in widespread use for cancers of the breast and cervix. The dismal status of ovarian cancer screening was underscored a year ago when an NIH-sponsored study showed that over 70 percent of cancers detected by transvaginal ultrasound and CA 125 biomarker testing — the two best ovarian screening tests we’ve got — had reached stage III or IV at the time the patients screened positive. That’s about what happens when women aren’t screened at all. That wasn’t the worst of it, however. In just the first year of that screening program, positiv... Better Health blogs http://www.medworm.com/rss/comments.php?id=4360981 Tue, 18 Jan 2011 02:00:12 +0100 4360981 http://www.medworm.com/index.php?rid=4349659&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2011%2F01%2F14%2Fcaris-life-sciences-launches-molecular-profiling-service-for-ovarian-cancer-patients%2F Caris Life Sciences announces the launch of a new molecular profiling service for ovarian cancer patients Caris Life Sciences, Inc. (Caris), a leading biosciences company focused on enabling precise and personalized healthcare through the highest quality anatomic pathology, molecular profiling, and blood-based diagnostic services, announced the launch of a new, Caris Target Now™ molecular profile [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=4349659 Fri, 14 Jan 2011 22:11:53 +0100 4349659 http://www.medworm.com/index.php?rid=4331094&cid=t_110280_113_f&fid=39278&url=http%3A%2F%2Fblogsite.mdbuyline.com%2F%3Fp%3D142 There is great news for cardiology: the reimbursement level for Myeloperoxidase will more than double for FY 2011. Myeloperoxidase is a protein biomarker found in the blood and is more commonly referred to as MPO.  First studied in 2003, it is an early predictor for chest pain patients who are at risk of a heart attack.  Each year, over 5 million patients seek treatment for chest pain in an ER and encounter a long list of possible chest pain causes; some causes can be ruled out with basic tests.  EKGs have been an excellent test for heart problems, but in more recent years, MPO has proven very effective as an early indicator.  When discovered early, physicians can prescribe preventative treatment before damage can occur.  However, reimbursement, in most cases was below the cost of the... MD Buyline blogs http://www.medworm.com/rss/comments.php?id=4331094 Tue, 11 Jan 2011 14:24:35 +0100 4331094 http://www.medworm.com/index.php?rid=4159429&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2010%2F11%2F11%2Fnew-assay-test-predicts-that-50-of-ovarian-cancers-will-respond-to-in-vitro-parp-inhibition%2F U.K. researchers develop a new test that could be used to select ovarian cancer patients who will benefit from a new class of drugs called “PARP inhibitors.” U.K. researchers have developed a new test that could be used to select which patients with ovarian cancer will benefit from a new class of drugs called “PARP [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=4159429 Fri, 12 Nov 2010 00:19:19 +0100 4159429 http://www.medworm.com/index.php?rid=4134151&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2010%2F11%2F02%2Fpeptide-being-tested-for-atherosclerosis-inhibits-ovarian-cancer-growth-clinical-trial-planned%2F A drug in testing to treat atherosclerosis significantly inhibited growth of ovarian cancer in both human cell lines and mouse models, marking the first such report of a peptide being used to fight malignancies, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center. A drug in testing to treat atherosclerosis significantly inhibited [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=4134151 Tue, 02 Nov 2010 22:59:25 +0100 4134151 http://www.medworm.com/index.php?rid=4133942&cid=t_110280_113_f&fid=39278&url=http%3A%2F%2Fblogsite.mdbuyline.com%2F%3Fp%3D79 Because the same vital angiogenic process that allows your body to heal itself also causes tumors to grow, computer-assisted tortuosity has emerged as a fascinating concept of identifying cancerous tumors by their blood vessel patterns.  With this method, researchers use the rapid formation of blood vessels as a physiological cancer biomarker, enabling a more accurate diagnosis and the rapid tracking of cancer therapy.  New perfusion imaging technologies have been used to study blood vessels at the micro level for years.  However, these were focused on flow and volume of blood, which has lead to an increased number of false positives and false negatives.  The next natural step in the evolution of angiogensis imaging is computerized blood vessel tortuosity.  I spoke to one of the leadi... MD Buyline blogs http://www.medworm.com/rss/comments.php?id=4133942 Tue, 02 Nov 2010 14:11:16 +0100 4133942 http://www.medworm.com/index.php?rid=4060591&cid=t_110280_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fdisease-detected-in-exhaled-breath%2F2010.10.12 A new sensor developed at Stony Brook University may become a clinically useful tool for detecting disease biomarkers in breath. The nanoprobe-based technology is currently able to detect acetone, but should be modifiable to spot other compounds. From the study abstract: This paper describes a sensor nanotechnology suitable for non-invasive monitoring of a signaling gas, such as acetone, in exhaled breath. This is a nanomedicine tool comprised of a selective acetone nanoprobe working on the principle of ferroelectric poling sensing, and a microelectronics circuit for comparing the actual sensor signal to a predetermined threshold value, displaying the result using LED signals. This on/off type non-invasive diagnostics platform technology is based on nanotechnology, gives a fast response, i... Better Health blogs http://www.medworm.com/rss/comments.php?id=4060591 Tue, 12 Oct 2010 12:00:13 +0100 4060591 http://www.medworm.com/index.php?rid=4055815&cid=t_110280_113_f&fid=39278&url=http%3A%2F%2Fblogsite.mdbuyline.com%2F%3Fp%3D56 I’m sure I’m not the only one who wonders why an early diagnosis for Alzheimer’s is so important if there is no cure.  In fact, there are several drugs out that can slow the disease progression and several on the way that promise to reverse the effects of Alzheimer’s.  Considering Alzheimer’s costs over $170 billion each year and is the seventh leading cause of death, early diagnosis can be crucial. Currently, PET scans are the only FDA-approved test to diagnose Alzheimer’s.  Other tests, such as clinical assessment, spinal fluid (tau protein), and EEGs, are used together in a process of elimination, diagnosing the disease with 80 to 90% accuracy.  Unfortunately, this combination of tests can total thousands of dollars and is far too expensive to be considered as a scre... MD Buyline blogs http://www.medworm.com/rss/comments.php?id=4055815 Mon, 11 Oct 2010 16:18:11 +0100 4055815 http://www.medworm.com/index.php?rid=3862152&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2010%2F08%2F12%2Fthe-cancer-biomarker-conundrum-too-many-false-discoveries%2F The boom in cancer [including ovarian] biomarker investments over the past 25 years has not translated into major clinical success. The reasons for biomarker failures include problems with study design and interpretation, as well as statistical deficiencies, according to an article published online August 12 in The Journal of the National Cancer Institute. The boom [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=3862152 Fri, 13 Aug 2010 04:40:30 +0100 3862152 http://www.medworm.com/index.php?rid=3858333&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2010%2F08%2F11%2Fgeorgia-techs-ovarian-cancer-early-detection-blood-test-exhibits-high-accuracy-in-small-study-larger-study-planned%2F Scientists at the Georgia Institute of Technology have attained very promising results on their initial investigations of a new test for ovarian cancer. Using a new technique involving mass spectrometry of a single drop of blood serum, the test correctly identified women with ovarian cancer in 100 percent of the 94 patients tested. Because of the extremely [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=3858333 Thu, 12 Aug 2010 02:50:07 +0100 3858333 http://www.medworm.com/index.php?rid=3269774&cid=t_110280_122_f&fid=34755&url=http%3A%2F%2Fneuropsychological.blogspot.com%2F2010%2F02%2Fneuropsychology-abstract-of-day.html Fjell AM, Walhovd KB, Fennema-Notestine C, McEvoy LK, Hagler DJ, Holland D, Brewer JB, Dale AM; for the Alzheimer's Disease Neuroimaging Initiative. CSF Biomarkers in Prediction of Cerebral and Clinical Change in Mild Cognitive Impairment and Alzheimer's Disease.J Neurosci., 2010 Feb, 10; 30(6): 2088-2101.Center for the Study of Human Cognition, Department of Psychology, University of Oslo, NO-0317 Oslo, Norway, Department of Neuropsychology, Ullevaal University Hospital, NO-0407 Oslo, Norway, and Departments of Radiology, Psychiatry, and Neuroscience, University of California, San Diego, La Jolla, California 92093.Brain atrophy and altered CSF levels of amyloid beta (Abeta(42)) and the microtubule-associated protein tau are potent biomarkers of Alzheimer's disease (AD)-related pathology. ... BrainBlog blogs http://www.medworm.com/rss/comments.php?id=3269774 Sat, 13 Feb 2010 09:57:00 +0100 3269774 http://www.medworm.com/index.php?rid=3259189&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2010%2F02%2F09%2Fabbott-labs-seeks-fda-510k-clearance-for-new-automated-ovarian-cancer-detection-test%2F A new diagnostic tool physicians can use to monitor patients for the most common form of ovarian cancer may soon be available in the United States. A new diagnostic tool physicians can use to monitor patients for the most common form of ovarian cancer may soon be available in the United States.  Abbott Laboratories’ (Abbott’s) ARCHITECT [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=3259189 Tue, 09 Feb 2010 22:24:31 +0100 3259189 http://www.medworm.com/index.php?rid=3208446&cid=t_110280_109_f&fid=34750&url=http%3A%2F%2Fpsychcentral.com%2Fblog%2Farchives%2F2010%2F01%2F26%2Fptsd-brain-scan-hype%2F Last week, we noted along with many news outlets that a biomarker had been apparently discovered for PTSD. The researchers claimed they had a new tool to help make a differential diagnosis of posttraumatic stress disorder (PTSD). The tool is a brain scanning technology that, like EEG, measures the brain’s electrical activity. But instead of directly measuring such activity, it measures magnetic fluctuations in the electrical activity. The technique is called MEG. There are certain technical benefits to this method as compared to a traditional EEG, so some researchers are exploring its greater use. Mind Hacks has a very good analysis of why the researchers’ claims were overreaching and a bit ridiculous: Crucially, the scan didn’t pick out cases of PTSD among people with ... World of Psychology blogs http://www.medworm.com/rss/comments.php?id=3208446 Tue, 26 Jan 2010 14:00:08 +0100 3208446 http://www.medworm.com/index.php?rid=3153592&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2010%2F01%2F07%2Felevated-proteins-may-warn-of-ovarian-cancer-but-sufficient-lead-time-predictive-value-still-lacking%2F Fred Hutchinson Cancer Center researchers discovered that concentrations of the serum biomarkers CA125, human epididymis protein 4 (HE4), and mesothelin began to rise 3 years before clinical diagnosis of ovarian cancer, according to a new study published online December 30 in the Journal of the National Cancer Institute. However, the biomarkers became substantially elevated only [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=3153592 Thu, 07 Jan 2010 22:22:08 +0100 3153592 http://www.medworm.com/index.php?rid=2984987&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2009%2F11%2F11%2Fucla-researchers-significantly-inhibit-growth-of-ovarian-cancer-cell-lines-with-fda-approved-leukemia-drug-dasatinib-sprycel%25c2%25ae%2F The drug dasatinib (Sprycel®), approved for use by the U.S. Food and Drug Administration in patients with specific types of leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, say UCLA researchers in the November 10th issue of the British Journal of Cancer. The drug, when paired with [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=2984987 Thu, 12 Nov 2009 00:45:53 +0100 2984987 http://www.medworm.com/index.php?rid=2800663&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2009%2F09%2F15%2Ffda-clears-vermillions-ova1-test-to-determine-likelihood-of-ovarian-cancer-in-women-with-pelvic-mass%2F The U.S. Food and Drug Administration cleared a test that can help detect ovarian cancer in a pelvic mass that is already known to require surgery. The test, called OVA1, helps patients and health care professionals decide what type of surgery should be done and by whom. First Lab Test That Can Indicate Ovarian Cancer Prior [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=2800663 Wed, 16 Sep 2009 04:45:59 +0100 2800663 http://www.medworm.com/index.php?rid=2670952&cid=t_110280_122_f&fid=34755&url=http%3A%2F%2Fneuropsychological.blogspot.com%2F2009%2F08%2Fneuropsychology-abstract-of-day_04.html CONCLUSIONS: This multicenter study found that CSF Abeta42, T-tau, and P-tau identify incipient AD with good accuracy, but less accurately than reported from single-center studies. Intersite assay variability highlights a need for standardization of analytical techniques and clinical procedures.PMID: 19622817 [PubMed - indexed for MEDLINE] (Source: BrainBlog) BrainBlog blogs http://www.medworm.com/rss/comments.php?id=2670952 Tue, 04 Aug 2009 13:52:00 +0100 2670952 http://www.medworm.com/index.php?rid=2662627&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2009%2F08%2F01%2Fnew-study-shows-four-year-window-for-early-detection-of-ovarian-cancer%2F A new study by Howard Hughes Medical Institute researchers shows that most early stage ovarian tumors exist for years at a size that is a thousand times smaller than existing tests can detect reliably.  But the researchers say their findings also point to new opportunities for detecting ovarian cancer—a roughly four-year window during which most [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=2662627 Sat, 01 Aug 2009 22:45:36 +0100 2662627 http://www.medworm.com/index.php?rid=2602203&cid=t_110280_137_f&fid=35426&url=http%3A%2F%2Fwww.alz.org%2Ficad%2Fdocuments%2Fabstracts%2Fabstracts_biomarkers_ICAD09.pdf Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer's, according to new research reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna.For more Insight into Alzheimer's DiseaseSubscribe to The Alzheimer's Reading RoomNew Results from ADNI Data Bring Us Closer to Earlier Detection of Alzheimer's Vienna, July 14, 2009 – Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer's, according to new research reported today at the Alzheimer's Association 2009 Inter... Alzheimer's Reading Room, The blogs http://www.medworm.com/rss/comments.php?id=2602203 Tue, 14 Jul 2009 16:24:42 +0100 2602203 http://www.medworm.com/index.php?rid=2523685&cid=t_110280_137_f&fid=35426&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FTheAlzheimersReadingRoom%2F%7E3%2FYZPGY8BrptI%2Fearly-and-easy-detection-of-alzheimers.html In this study, an NIR biospectroscopy analysis was conducted on blood plasma samples from a total of 63 subjects, 19 with Alzheimer’s disease, 27 with mild cognitive impairment (a frequent indication of Alzheimer’s disease) and 17 normal elderly controls, to measure the degree of oxidative stress in plasma. OS is caused by a chemical imbalance that can damage critical components of cells and biofluids, including proteins, lipids and DNA. OS is known to be involved in many neurological diseases, including Alzheimer's and Parkinson’s disease.In differentiating Alzheimer’s disease patients from the normal elderly control group, NIR achieved a sensitivity of 80% and specificity of 77%. Fifteen and twelve patients with mild cognitive impairment were classified with the normal elderly co... Alzheimer's Reading Room, The blogs http://www.medworm.com/rss/comments.php?id=2523685 Wed, 17 Jun 2009 18:58:46 +0100 2523685 http://www.medworm.com/index.php?rid=2453074&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2009%2F05%2F31%2Fearly-treatment-of-recurrent-ovarian-cancer-based-upon-rising-ca-125-levels-does-not-increase-survival%2F “European researchers report [at the 2009 American Society of Clinical Oncology Annual Meeting being held in Orlando, Florida from May 29 through June 2nd] that starting treatment early for an ovarian cancer relapse based on CA125 blood levels alone does not improve overall survival, compared with delaying treatment until symptoms arise.” PLENARY PRESENTATION SUNDAY, MAY 31, 1:45 [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=2453074 Sun, 31 May 2009 23:41:47 +0100 2453074 http://www.medworm.com/index.php?rid=2349514&cid=t_110280_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2009%2F04%2F15%2Fsenator-barbara-boxer-reintroduces-legislation-to-better-diagnosis-ovarian-cancer%2F On March 31, 2009, U.S. Senator Barbara Boxer (D-CA) reintroduced the Ovarian Cancer Biomarker Research Act of 2009 (H.R. 1816) legislation to develop new technologies to detect and fight ovarian cancer.  The Ovarian Cancer Biomarker Research Act bill, if ultimately enacted as law, would authorize $30 million each year for four years to fund research [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=2349514 Thu, 16 Apr 2009 03:44:30 +0100 2349514 http://www.medworm.com/index.php?rid=1769440&cid=t_110280_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F383877706%2F Conclusion My thanks to everyone that contributed articles — it’s been great hosting the Cancer Research Blog Carnival for a second time this year. Be sure to take a moment and let your fellow bloggers know this issue is available so that everyone’s hard work can be appreciated and enjoyed by all. The Cancer Research Blog Carnival is looking for future hosts. You can find both the hosting schedule and past editions at the Cancer Research Blog Carnival website. For more information on the U.S. investment in cancer research, you can read the NCI’s plan and budget proposal for fiscal year 2009. References Niederhuber JE. A look inside the National Cancer Institute budget process: implications for 2007 and beyond. Cancer Res. 2007 Feb 1;67(3):856-62. View abstract The ... Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1769440 Fri, 05 Sep 2008 04:49:31 +0100 1769440 http://www.medworm.com/index.php?rid=1689065&cid=t_110280_133_f&fid=35096&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2FkbEbbL-9wK0%2F Tomorrow, August 7th, from 11 am to 3 pm EST, there will be a meeting of the Meeting of the Interagency Autism Coordinating Committee (IACC) Autism Strategic Plan Implementation Workgroup. The purpose of the meeting is to discuss budgetary requirements for the IACC Strategic Plan for Autism Spectrum Disorders (ASD) Research; workgroup findings will be forwarded to the IACC for consideration and discussion at the next committee meeting on November 21, 2008. You can listen in to the workgroup meeting through a conference call phone number and a web presentation tool on the Internet. Click this link to join the Webinar: https://www1.gotomeeting.com/register/921061447 [(Please note this information has been corrected, thanks to Regan] Or, call this conference call phone number: (888) 455-2920 ... Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1689065 Thu, 07 Aug 2008 11:23:41 +0100 1689065 http://www.medworm.com/index.php?rid=1531376&cid=t_110280_133_f&fid=35096&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2F315546894%2F The earlier part of this year saw the publication of a number of studies about the genetics of autism, with one scientist speculating about a unified theory of autism. The July 2008 Nature Genetics has a review of psychiatric genetics that considers progress and controversy. Here is the abstract: Several psychiatric disorders — such as bipolar disorder, schizophrenia and autism — are highly heritable, yet identifying their genetic basis has been challenging, with most discoveries failing to be replicated. However, inroads have been made by the incorporation of intermediate traits (endophenotypes) and of environmental factors into genetic analyses, and through the identification of rare inherited variants and novel structural mutations. Current efforts aim to increase sample sizes by ga... Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1531376 Thu, 19 Jun 2008 16:39:08 +0100 1531376 http://www.medworm.com/index.php?rid=1478520&cid=t_110280_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F300767873%2F This article was published on Highlight HEALTH. Related articlesCancer Research Carnival #7Treating Cancer with Personalized MedicineHEALTH Highlights - August 9th, 2007March is National Colorectal Cancer Awareness MonthCancer Prevention (Source: Highlight HEALTH) Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1478520 Thu, 29 May 2008 20:22:36 +0100 1478520 http://www.medworm.com/index.php?rid=1478018&cid=t_110280_131_f&fid=34989&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F300502200%2F P52 gene, arrows show locations of common mutations  (Image courtesy www.bioinf.org) Following on from my last article on using gene therapy for increasing survival in head and neck cancer, Professor Jack Roth, M.D., professor in M. D. Anderson’s Department of Thoracic & Cardiovascular Surgery and colleagues are now focusing on ways to deliver p53 and other tumor-suppressing genes systemically - through intravenous delivery. The p53 gene is inactivated in many types of cancer. Its normal role is to halt the division of a defective cell and then force the cell to kill itself. Advexin has to be injected straight into the tumor, but that’s not workable for many cancers. Head and neck cancer kills patients by recurring, not spreading to other organs, but most cancer deaths in... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1478018 Thu, 29 May 2008 11:47:11 +0100 1478018 http://www.medworm.com/index.php?rid=1420488&cid=t_110280_133_f&fid=35096&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2F284107843%2F What do TV, ultrasounds, insufficient vitamin D, air pollution, a mother having the flu while pregnant, mercury, have to do with each other? All have been named as possible causes of autism. TK Kenyon looks at the puzzling spectrum of research into the cause of autism, some of which he labels as “just plain stupid”—the theory by economist Michael Waldman that tv causes autismautism causes tv—while others are “brilliant”—a 2006 study published in the Proceedings of the National Academy of Sciences (PNAS), about a genetic variant that disrupts the transcription of MET, a gene that is a tyrosine kinase receptor and that “participates in brain growth and maturation, immune function, and repair of the digestive system.” As Kenyon further not... Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1420488 Mon, 05 May 2008 19:10:45 +0100 1420488 http://www.medworm.com/index.php?rid=1389077&cid=t_110280_133_f&fid=35096&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2F274756290%2F Today, April 21st, from 11 am to 6 pm EST, there will be a meeting of the Strategic Planning Workgroup formed by the Interagency Autism Coordinating Committee (IACC). You can “attend” the workgroup meeting through a conference call phone number and a web presentation tool on the Internet. Click this link to join the Webinar: https://www1.gotomeeting.com/join/630812808/106536587 Webinar ID: 630-812-808 Or, call this conference call phone number: (641) 715-3222 Access code: 693-119-10. More details about the meeting here. Tags: asd, asperger, autism, biology, biomarker, Diagnosis, Environment, funding, Genetics, Health, nih, pdd-nos, Science, VaccinesShare This (Source: Autism Vox) Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1389077 Mon, 21 Apr 2008 15:00:31 +0100 1389077 http://www.medworm.com/index.php?rid=1368412&cid=t_110280_133_f&fid=35096&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2F268992437%2F The Interagency Autism Coordinating Committee (IACC) coordinates efforts to research, educate, and screen for autism with the Department of Health and Human Services (go here for more information on the IACC). On Monday, April 21st from 11 am to 6 pm EST, there will be a meeting of the Strategic Planning Workgroup formed by the IACC. Workgroup members will review the current funding for research on autism, as well as proposed research initiatives and resources, and will discuss and make recommendations on what research initiatives to prioritize for the IACC’s strategic plan for ASD research. You can “attend” the workgroup meeting through a conference call phone number and a web presentation tool on the Internet. Members of the public who participate using the conference c... Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1368412 Sat, 12 Apr 2008 15:16:13 +0100 1368412 http://www.medworm.com/index.php?rid=1344332&cid=t_110280_133_f&fid=35096&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2F262500753%2F The April 1st CNN Money.com reviews the “recent brouhaha about 9-year-old Hannah Poling,” whose family received a settlement under the federal government’s Vaccine Injury Compensation Program “based on their claim that childhood vaccinations aggravated a rare metabolic disorder in Hannah, triggering autism symptoms.” Writer David Stipp notes that, in a 2006 survey, 54% of families claimed that vaccines caused their children to become autistic and comments on how proponents of such a view have “hailed the decision as unprecedented support” that vaccines or something in vaccines can be linked to autism and to rising autism rates, in despite of more and more scientific evidence that dispute an autism-mercury link. Herein lies, Stipp writes, “one... Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1344332 Wed, 02 Apr 2008 08:00:20 +0100 1344332 http://www.medworm.com/index.php?rid=1340673&cid=t_110280_133_f&fid=35096&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2F261737668%2F It’s April 1st and the start of “Autism Awareness Month”: There’ll be plenty in the news about autism and also appeals to support research—and what kind of research, in particular? Last year (FY 2007), the National Institutes of Health (NIH) devoted $127 million to research autism spectrum disorders through “grants, contracts, research projects conducted as part of the NIH Intramural Research Program, and other mechanisms of support.” In addition, NIH invested $3.9 million in the development of the National Database for Autism Research (NDAR). In FY 2006, $108 million was devoted to research on ASD’s. By way of comparison, in FY 2007, $107 million was devoted by the NIH to research on ADHD; $16 million was devoted to research on Cerebral Pals... Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1340673 Tue, 01 Apr 2008 05:15:50 +0100 1340673 http://www.medworm.com/index.php?rid=1049082&cid=t_110280_134_f&fid=36049&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FDiabetesNotes%2F%7E3%2F190390259%2F Glucose and fructose are metabolized in the liver. When there’s too much sugar in the diet, the liver converts it to lipid. Using a mouse model and human liver cell cultures, the scientists discovered that the increased production of lipid shut down a gene called SHBG (sex hormone binding globulin), reducing the amount of SHBG protein in the blood. SHBG protein plays a key role in controlling the amount of testosterone and estrogen that’s available throughout the body. This would indicate that the bodies liver metabolism is all “out of whack” before there are even disease symptoms and we could in turn use SHGB as a bio-marker for liver function. Pretty good idea, huh? Less SHGB protein means more testosterone and estrogen released in the body and an increased risk for infer... Diabetes Notes blogs http://www.medworm.com/rss/comments.php?id=1049082 Sun, 25 Nov 2007 21:30:42 +0100 1049082 http://www.medworm.com/index.php?rid=989975&cid=t_110280_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F176992243%2F A possible biomarker for colon cancer in people aged 50 and younger have been identified by Mayo Clinic researchers. Colon cancer, also called colorectal cancer or bowel cancer, includes cancerous growths in the colon, rectum and appendix. It’s the second leading cause of cancer death in the United States, affecting nearly 145,000 people each year. The first cases tend to appear in people in their 40s, but most patients tend to be in their mid 60s by the time they are diagnosed. The said biomarker – shortened telomeres - is the same abnormality of chromosomes previously associated with diseases of aging. The Mayo Clinic team led by Lisa Boardman, M.D., a specialist in gastrointestinal malignancies, investigated the structures inside of cells known as telomeres, which are the caps o... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=989975 Tue, 30 Oct 2007 03:19:59 +0100 989975 http://www.medworm.com/index.php?rid=524347&cid=t_110280_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F04%2F05%2Fnew-test-confirms-the-danger-of-trans-fats%2F This study will appear in the April 10, 2007 print issue of Circulation: Journal of the American Heart Association.Read | Permalink | Email this | Linking Blogs | Comments (Source: The Cardio Blog) The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=524347 Thu, 05 Apr 2007 04:00:00 +0100 524347