MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'buse'. Sat, 03 Sep 2011 02:58:39 +0100 http://www.medworm.com/index.php?rid=1037877&cid=t_124383_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F187721284%2F A US Senate committee has asked to interview the Bill & Melinda Gates Foundation’s top health official as part of an ongoing investigation into whether he and others at his former company attempted to intimidate a scientist who revealed dangers about Glaxo’s Avandia diabetes pill, The Seattle Times reports. The Senate Finance Committee is reviewing allegations that Tadataka “Tachi” Yamada and other former SmithKline Beecham execs tried to stifle criticism from John Buse, a University of North Carolina diabetes expert, who told a medical conference that Avandia could cause potential fatal side effects, including heart attacks. Yamada, who is now president of the Gates Foundation’s global health program, was head of research for SmithKline - which later mer... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1037877 Tue, 20 Nov 2007 14:16:22 +0100 1037877 http://www.medworm.com/index.php?rid=1033102&cid=t_124383_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F185953393%2F The headline may have grabbed your attention, but the thrust of a report released late yesterday by the Senate Finance Committee is anti-climatic. For those who don’t recall, however, we will remind you that John Buse, a diabetes expert and professor at the University of North Carolina was systmetically threatened by Glaxo because he publicly expressed concerns that the Avandia diabetes pill may cause cardiovascular risks. This became known last spring in the run up to Congressional hearings into the FDA’s review of Avandia, which was linked to a 43 percent increased risk of heart attacks in a controversial meta-analysis published last May in The New England Journal of Medicine. The Glaxo drug now carries two Black Box warnings - for heart failure and heart attack risks. But th... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1033102 Fri, 16 Nov 2007 20:23:57 +0100 1033102 http://www.medworm.com/index.php?rid=908787&cid=t_124383_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F162053124%2F Which doctor? John Buse, the University of North Carolina diabetes researcher, who several years ago complained to Glaxo about Avandia risks and marketing. To keep him quiet, Glaxo threatened him with a $4 billion lawsuit. This became known shortly before Congress held hearings into Avandia last June. Now, The New Scientist reports (subscription required) that written conversations about how to deal with Buse took place at Glaxo’s “highest levels.” Apparently, internal e-mails given to Senate investigators this month show that several execs, including Garnier, Glaxo’s ceo, knew of plans to pressure Buse, according to the mag. One email, entitled “Avandia Renegade”, was sent in June 1999 by senior vp William Claypool (of the former SmithKline Beecham) to... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=908787 Thu, 27 Sep 2007 16:12:15 +0100 908787 http://www.medworm.com/index.php?rid=674826&cid=t_124383_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F6%2F9%2Ftruth-and-consequences-the-sad-tale-of-avandia-gsk-the-fda-a.html Medical science has always benefited from a healthy debate about the risks and benefits of various treatments. Doctors and other health professionals are trained to think critically about published data and to be cautious about recommending new (and old) treatments that have not met the highest standards of safety and efficacy. GSK's Avandia (from the News&Observer)Then they leave the relatively protected environment of their training institutions and enter the real world of high pressure, big business that is medicine today. Squeezed by time pressures, struggles over reimbursement, marketeers pushing their products, and patients demanding stuff they see on TV, they start to prescribe products and recommend treatments that they may not have under different circumstances. I’ve bee... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=674826 Sat, 09 Jun 2007 22:22:07 +0100 674826 http://www.medworm.com/index.php?rid=676283&cid=t_124383_134_f&fid=35137&url=http%3A%2F%2Fdiabetesupdate.blogspot.com%2F2007%2F06%2Fresearcher-threatened-with-4b-suit-for.html Here, from the Boston Globe, are more details about how John Buse, the mainstream researcher who will be the next ADA presidents, was threatened by GlaxoSmithKline, the maker of Avandia, for calling attention to its tendency to cause heart problems.Scientist says executive of Avandia firm tried to bully - Boston GlobeFrom the article:"An executive of the company that makes the diabetes drug Avandia said a researcher who was among the first to link it to heart problems would be held liable for the $4 billion GlaxoSmithKline PLC lost in stock value as a result of his findings, Dr. John B. Buse testified before congressional investigators yesterday.This information came from testimony, under oath, to congress."Buse told the House Committee on Oversight and Government Reform that he raised con... Diabetes Update blogs http://www.medworm.com/rss/comments.php?id=676283 Fri, 08 Jun 2007 12:42:00 +0100 676283