MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'calorie restriction'. Sat, 03 Sep 2011 02:17:30 +0100 http://www.medworm.com/index.php?rid=4183294&cid=t_103888_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fthe-twinkie-diet%2F2010.11.19 “Hey…where did those cupcakes go?” Like a never-ending western North Carolina climb where each switchback reveals another uphill, and the finish is shielded by tall pines, the struggle to lose weight and to stay lean is incessant. In wrestling weight gain, competitive cyclists share the same mat as “regular” Americans. Like jockeys, all competitive bike racers strive for maximal leanness. It’s physics: Weigh less and the same number of watts push you farther and faster, especially when going uphill or accelerating from a slow speed. Remember those velocity problems in Physics 101? But is it conceivable that losing weight — even if accompanied by lower cholesterol levels — could be detrimental to long-term wellness? Obviously, the question answers itself... Better Health blogs http://www.medworm.com/rss/comments.php?id=4183294 Fri, 19 Nov 2010 21:00:00 +0100 4183294 http://www.medworm.com/index.php?rid=3762903&cid=t_103888_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fwill-science-succeed-with-an-anti-aging-revolution%2F2010.07.17 Wouldn’t it be great if we could find a way to prolong our lives and to keep us healthy right up to the end? Ponce de León never found that Fountain of Youth, but science is still looking. What are the chances science will succeed? How’s it doing so far? In his new book The Youth Pill: Scientists at the Brink of an Anti-Aging Revolution, David Stipp tries to answer those questions. From the title of the book, I expected hype about resveratrol or some other miracle pill, but instead it is a nuanced, levelheaded, entertaining, informative account of the history and current state of longevity research. It makes that research come alive by telling stories about the people involved, the failures and setbacks, and the agonizingly slow process of teasing out the truth with a series of experi... Better Health blogs http://www.medworm.com/rss/comments.php?id=3762903 Sat, 17 Jul 2010 12:00:59 +0100 3762903 http://www.medworm.com/index.php?rid=3545642&cid=t_103888_160_f&fid=36189&url=http%3A%2F%2Fwww.skinmdblog.com%2F74%2Fskin-pigmentation-genetics-the-sun-aging%2F Skin pigmentation is caused by the hormone melanin.  It is produced by specialized cells called melanocytes located in the deepest of the skin’s layers. Your genes are partially responsible for the amount of melanin present in your skin’s cells.  Other than that, sun exposure is the primary cause of increased melanin production. There are some medical conditions (mostly hormonal changes) that will cause increased melanin production.  Sometimes the melanin clumps or forms patches.  The appearance of clumps or patches can be distressing.  They are sometimes referred to as age spots. Although getting older may play a role, everyone wants to live a long life.  So, inevitably everyone will get older. What many people hope to do is to minimize the damage that time does to their faces a... Skin MD blogs http://www.medworm.com/rss/comments.php?id=3545642 Sat, 08 May 2010 12:40:59 +0100 3545642 http://www.medworm.com/index.php?rid=2406284&cid=t_103888_167_f&fid=38271&url=http%3A%2F%2Frebeccascritchfield.wordpress.com%2F2009%2F05%2F11%2Ffeeling-the-squeeze-of-restrictive-dieting%2F Thanks to Brandi for letting me troll as a guest blogger at Diets In Review. Read an excerpt from my post below and then check out the full article! Originally published at DietsInReview.com If you’ve ever lost weight by cutting calories then you can understand the allure of restricting further to accelerate weight loss. But just because a little is good – more is not better. An eating plan that is too restrictive is a first-class ticket to sabotage. Find out if your current plan needs loosening up. You cut out foods you love. If your diet has you avoiding specific foods, especially ones you love, it is essentially setting you up for failure. There’s no reason that even the most “forbidden” food can’t be included in a healthy eating plan. You deserve to love the foods you eat. ... Balanced Health and Nutrition Rebecca Scritchfield's Blog blogs http://www.medworm.com/rss/comments.php?id=2406284 Mon, 11 May 2009 05:37:26 +0100 2406284 http://www.medworm.com/index.php?rid=2173829&cid=t_103888_122_f&fid=36582&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FSharpBrains%2F%7E3%2F536195658%2F Welcome to the 8th edition of Hourglass, the blog carnival devoted to biogerontology. Enjoy! --- Use It or Lose It Existence is Wonderful, by Anne C. Neither A Transhumanist Nor a "Pessimist", And That's Okay "I can't survive cognitively in environments that force everything into false dichotomies, and nobody should feel hurt, slighted, or bitter because of my doing what I need to do for the sake of being able to actually use my brain." "Just because I think superlativity tends to distort dialogue and make it difficult to focus on what can actually be done in the real world does not mean I disparage the power of human imagination or our capacity to change things for the better." --- Cognitive Enhancement, Health and Assessments Ouroboros, by Chris Pa... SharpBrains blogs http://www.medworm.com/rss/comments.php?id=2173829 Tue, 10 Feb 2009 15:00:32 +0100 2173829 http://www.medworm.com/index.php?rid=1432386&cid=t_103888_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2008%2F5%2F9%2Fwant-to-live-to-100-read-this.html By Dov Michaeli MD, Ph.DIn 2005 National Geographic magazine had a fascinating article by Dan Buettner, about the “Blue Zones”, areas where people live to the ages of 90, 100 and older. These areas included Loma Linda, CA, Sardinia Italy, Okinawa Japan, and the Nicoya peninsula in Costa Rica. He followed up his trip to Costa Rica with a more extensive visit, including a team of researchers, in 2007. One of the pitfalls of studies of this sort is the verification of claims of age. For instance, a claim that made a big splash in the media several years ago concerned Bulgarian villagers who claimed that their secret to longevity is eating yogurt. A craze of yogurt swept the U.S. following publication of this story, which I am not sure has completely disappeared. That "study&q... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=1432386 Fri, 09 May 2008 03:34:55 +0100 1432386 http://www.medworm.com/index.php?rid=1057285&cid=t_103888_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F11%2F28%2Fwant-to-live-longer-forget-starvation-diet.html By Dov Michaeli MD, Ph.D“Go to the ant, my sonObserve her waysAnd wisen”King Solomon, Proverbs (free translation).Undoubtedly you have seen pictures of those emaciated characters who practice calorie restriction in the name of living a long, long life. The normal daily diet of an adult male contains about 2000-2400 calories. The ‘calorie restriction’ people limit their diet to about half of that. They may live longer, but are they happier? Hard to tell; they are going to die hungry but maybe also happy, for the ordeal is finally over. One of the organisms that provided the ‘intellectual’ basis for this cruel and unusual experiment in long living is called C. elegans.Where in the world is C. elegans?Caenorhabditis elegans (Caeno, recent; rhabditis, rod; e... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=1057285 Wed, 28 Nov 2007 02:16:05 +0100 1057285 http://www.medworm.com/index.php?rid=797967&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001283.php The science behind the work of groups like Sirtris Pharmaceuticals is based on the study of calorie restriction (CR) and sirtuins - but are sirtuins actually at the root of the biology that drives extended health and longevity through CR? A few contrary positions exist, as is usually the case when research in a field is still dynamic and unfolding. An informative post from Michael Rae can be found in the Methuselah Foundation forums: "Sirtuin Activation" as the Mechanism of CR and its Putative Mimetics Kaeberlein is a former grad student of Leonard Guarente's, and collaborated with him on many studies on "long-lived" mutants of the common yeast Saccharomyces cerevisiae. However, he's become an increasingly vocal critic of the thesis -- first advanced by Guarente, and promulgated even mor... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=797967 Mon, 13 Aug 2007 04:00:00 +0100 797967 http://www.medworm.com/index.php?rid=714760&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001255.php The fifth annual Calorie Restriction Society conference will be held later this year - another good chance to learn more about the science and practice of calorie restriction with the intent to extend healthy longevity and reduce risk of age-related disease. One of the highlights of the healthy life extension community, they illustrate the right way to develop ties to the scientific community and help to push forward and encourage research: The fifth CR Society Conference (CR V) will be held in San Antonio Texas, November 7-11, 2007. The current roster of participating scientists includes Steven Austad, Rochelle Buffenstein, John Holloszy, Jim Nelson, Jay Phelan, Arlan Richardson, Walter Ward, and Bradley Willcox. We also will include presentations by members of the Society. More informa... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=714760 Wed, 04 Jul 2007 04:00:00 +0100 714760 http://www.medworm.com/index.php?rid=693217&cid=t_103888_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F6%2F25%2Fwomen-with-breast-cancer-can-lower-their-risk-of-dying-by-50.html It has been well-documented that women could reduce their risk of being diagnosed with breast cancer by eating vegetables and fruits, exercising and keeping a non-obese BMI (>25). But the pervasive feeling among physicians (yours truly included) was that once cancer is diagnosed, changes in life style are too little too late. But a recent study (Journal of Clinical Oncology, vol. 25, pp. 2345-2351, 2007) looked at this issue, and the results were totally unexpected. How the study was done A prospective study was performed of 1,490 women diagnosed and treated for early-stage breast cancer between 1991 and 2000. Enrollment was an average of 2 years postdiagnosis. An analysis of the effect of interaction between different factors on survival (called multivariate analysis) found t... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=693217 Mon, 25 Jun 2007 00:32:52 +0100 693217 http://www.medworm.com/index.php?rid=645118&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001226.php The folk of the Calorie Restriction (CR) Society are continuing their efforts to raise funds to broaden human CR research with a fundraising event in August. As for many successful health-oriented organizations, the Society prospers through close ties with the research community - just look at any of their conferences in recent years. As Mary Robinson relates: At last year's CR Conference, we all told Dr. Spindler that we would raise the money for him to do a human study on gene expression in CR - on us. This is a cool idea in so many ways. From all the moaning and groaning from the calorie restriction researchers at the conference, it is very clear that they are having a hard time getting funding from NIH. It's not a disease, after all - aging. Or is it? Spindler also thought it would be... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=645118 Sun, 27 May 2007 04:00:00 +0100 645118 http://www.medworm.com/index.php?rid=577156&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001197.php If you haven't been practicing calorie restriction for most of your life, there's not a lot you can do (yet) about the irreversible damage done to your body so far - broken molecules and broken systems that cannot be repaired naturally. Aging is nothing more than the consequences of that irreversible damage, and you've been accumulating it faster than you might have been. That's past and done now. Still, it appears that adopting calorie restriction even late in life brings meaningful benefits: Physiological changes associated with ageing include cell damage and the emergence of cancer cells. The most important effects of low calorie diets and longevity therapeutics given late in life may not be to prevent this damage, but instead to stimulate the body to eliminate damaged cells that may b... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=577156 Sat, 28 Apr 2007 04:00:00 +0100 577156 http://www.medworm.com/index.php?rid=565561&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001192.php Following feelings - or even experience - rather than the findings of the scientific community is not the best path forward under most circumstances. A piece on calorie restriction and anorexia by a recovered anorexic at Slate is very illustrative of this point: As a former anorexic, I've found it strange to hear scientists hail low metabolism - a central feature of that disease - as a sign of health and potential longevity. When I was being treated, my doctors invoked my low metabolism as a catchall for the physical damage I was doing. My low heart rate, amenorrhea (the loss of my period), and the goose bumps I got in 70-degree weather were all signs of illness. So, how can something that is a symptom of disease in one person be a marker of good health in another? ... The same thing ha... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=565561 Mon, 23 Apr 2007 04:00:00 +0100 565561 http://www.medworm.com/index.php?rid=542785&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001182.php There certainly is a great deal of published work coming out on calorie restriction and the related regulation of metabolism for greater health and longevity; funding for development based upon this field over the past year or two has no doubt further accelerated basic research. For all that I feel this ongoing metabolic examination and manipulation - aimed at slowing rather than repairing aging - is not the best path forward, it is still interesting work. Here are pointers to a couple of recent papers: Ruminations on dietary restriction and aging: Calorie restriction has been known for many decades to extend the life span of rodents. Since the more recent discovery that a long-term reduction in nutrient intake also extends life span in nearly every invertebrate model organism used for a... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=542785 Fri, 13 Apr 2007 04:00:00 +0100 542785 http://www.medworm.com/index.php?rid=520497&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001172.php Scientists are chewing over the past year of advances in calorie restriction and calorie restriction mimetic research, as indicated by a couple of recent papers on the subject. Vertebrate aging research 2006: The year's highlights include studies of oxidation damage in the very-long-lived naked mole-rat, and of caloric restriction in monkeys, humans, and growth hormone-unresponsive mice. Two studies of resveratrol, one showing its ability to extend lifespan in a short-lived fish, the other demonstrating beneficial effects in mice subjected to a diet high in fat, may well be harbingers of a parade of intervention studies in the coming decade. Starving for Life: What Animal Studies Can and Cannot Tell Us about the Use of Caloric Restriction to Prolong Human Lifespan: Caloric restriction ... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=520497 Tue, 03 Apr 2007 04:00:00 +0100 520497 http://www.medworm.com/index.php?rid=506081&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001165.php The Calorie Restriction Society is making available DVDs of the last three Society conferences, held in 2003, 2004 and 2006. There are two DVDs for each conference (Volume 1 and Volume 2). Each stores about 7 hours of video, for a total of about 14 hours of video for each conference. This allows essentially all the talks at each conference to fit onto the two DVD set. The DVDs are packaged in a slim plastic case, which takes up very little space. They use the DVD-R media type and the VCD encoding format which play on most (more than 90%) of DVD players, and essentially all computers with a working DVD ROM drive. You can find a list of the contents by following the links below: CR-IV (2006 Conference) DVDs 2004 Conference (CR-III) DVDs CR-II (2003 Conference) DVDs There is a strong emp... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=506081 Tue, 27 Mar 2007 04:00:00 +0100 506081 http://www.medworm.com/index.php?rid=482273&cid=t_103888_87_f&fid=34980&url=http%3A%2F%2Fwww.fightaging.org%2Farchives%2F001146.php CONCLUSIONS: Calorie restriction in adult men and women causes beneficial metabolic, hormonal, and functional changes, but the precise amount of calorie intake or body fat mass associated with optimal health and maximum longevity in humans is not known. In addition, it is possible that even moderate calorie restriction may be harmful in specific patient populations, such as lean persons who have minimal amounts of body fat. All of this should be just as much common sense on diet and health as avoiding the accumulation of excess fat and exercising regularly. Eat less, but obtain adequate nutrition - calorie restriction is not starvation No-one knows the absolute, optimal, best level of calorie restriction for you - and no-one is likely to find out any time soon But an 80/20, unoptimized... Fight Aging! blogs http://www.medworm.com/rss/comments.php?id=482273 Thu, 08 Mar 2007 05:00:00 +0100 482273