MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'cancer drug'. Sat, 03 Sep 2011 02:11:00 +0100 http://www.medworm.com/index.php?rid=4976158&cid=t_131465_136_f&fid=39212&url=http%3A%2F%2Fbahtocancer.com%2F2011%2F06%2Ftennis-again-2%2F This time last year, I wrote this post, about how tennis and birthdays are all wrapped up in memory with the drug trial that left me looking like a sunburned turnip and afraid I was going to die. (Or look like a sunburned turnip forever.) And this time last year, I wondered how I’d be feeling about it all now. Well, the short answer is.. not as good as I’d hoped. The fact that the anniversary of the Amazing Exploding Head is all tied up with tennis and my approaching birthday means that it’s impossible to miss. All of us are a little bit shaky. Alan and I were talking about it the other day, and we think the whole thing was so horrible not just because of the whole turnip/death thing, but because we were utterly unprepared for it. If we were Andy Murray, we’d have ... Bah! to cancer blogs http://www.medworm.com/rss/comments.php?id=4976158 Mon, 27 Jun 2011 07:40:33 +0100 4976158 http://www.medworm.com/index.php?rid=4945201&cid=t_131465_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FCwErfhk-Fqs%2F The FDA is often criticized for moving too slowly to approve new drugs, especially those for cancer. But is the agency as slow as some believe? To explore the question, researchers examined 35 oncology meds that were reviewed by the FDA and the European Medicines Agency between 2003 and 2010, and found the median approval time in the US took about half the time spent in Europe. Specifically, the median time for approval for new cancer meds in the US was six months, according to the paper by Friends of Cancer Research, a non-profit think tank that published the results in Health Affairs (read the abstract). However, they did not review initial approvals or supplemental applications, so their analysis did not include prominent secondary uses for drugs already on the market. The FDA approved ... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4945201 Thu, 16 Jun 2011 13:50:37 +0100 4945201 http://www.medworm.com/index.php?rid=4758709&cid=t_131465_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2011%2F04%2F27%2Fjournal-of-the-american-medical-association-2011-vol-305-no-5%2F The objective of this study is to perform a systematic review and meta-analysis of published randomised controlled trials (RCTs) to determine the overall risk of fatal adverse effects (FAEs) associated with bevacizumab, an angiogenesis inhibitor, used in conjunction with chemotherapy. The article concludes that in a meta-analysis of RCTs, bevacizumab in combination with chemotherapy or biological therapy, compared with chemotherapy alone, was associated with increased treatment-related mortality. An NHS Athens password is required to access this article online, alternatively contact the Library for a copy of this article Filed under: Athens Password, Current Awareness, E-Journals, Journals Tagged: Bevacizumab, Cancer, Drug Therapy, Fatal Adverse Effects, Randomised Controlled Trials (Sourc... Fade Library blogs http://www.medworm.com/rss/comments.php?id=4758709 Wed, 27 Apr 2011 10:26:16 +0100 4758709 http://www.medworm.com/index.php?rid=4429224&cid=t_131465_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2F1F3Beuifq9s%2F Certainly, at hospitals. In fact, the shortage of injectable generics for cancer and other serious diseases is forcing many hospitals to scramble to locate meds or find alternatives. In some cases, the FDA has allowed imports, but the agency approval process has also meant fewer new available generics. “We think this is near a crisis situation,” Bona Benjamin, a director at the American Society of Health-System Pharmacists, a pharmacist trade group, tells The Wall Street Journal. Numbers, of course, help tell the story. The FDA reports a record 178 drug shortages in 2010, up from 157 the year earlier and 55 five years ago. And here is the latest list. You’ll notice this is much shorter than the list indicating shortages that have been resolved (take a peek). The problem,... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4429224 Wed, 02 Feb 2011 18:03:31 +0100 4429224 http://www.medworm.com/index.php?rid=3903132&cid=t_131465_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FCrRCUDEW_yE%2F Good morning, everyone. Nice to see you again. After a protracted stretch, we have returned to the Pharmalot corporate campus, where a spot of rain is falling. We are keeping busy, of course, with the usual routine. What about you? Meetings and deadlines beckon, no doubt. Meanwhile, a hearty thanks to the many folks who attended our panel discussion at the American Chemical Society meeting yesterday. And now, as the world turns… India’s Health Minister Worries About Takeovers And Rx Prices (DNA) Drug Combo Helped Kill Cancer In Mice (Reuters) Insulin Users Have Higher Cancer Risk (Bloomberg News) Drugs And Talk Therapy May Ease Adult ADHD (Reuters) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3903132 Wed, 25 Aug 2010 12:08:40 +0100 3903132 http://www.medworm.com/index.php?rid=3885343&cid=t_131465_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Favastin-for-breast-cancer-will-the-fda-revoke-it%2F2010.08.19 Time to get back up on my soap box. Next month the FDA is supposed to consider taking the unique, first-time-ever step of revoking a drug’s indication not because it’s dangerous, but because it doesn’t work well enough to offset its risks. Never mind that it costs about $8,000 a month. The drug is Avastin (bevacizumab), a targeted monoclonal antibody that prevents tumors from creating and maintaining their own blood supply, a process called angiogenesis. Without oxygen and nutrients from blood, tumors can’t keep growing. Avastin is the world’s best-selling cancer drug, approved for use with chemotherapy to treat lung cancer and metastatic colorectal and breast cancer. It is also being investigated (and, likely, being prescribed off label) for numerous other c... Better Health blogs http://www.medworm.com/rss/comments.php?id=3885343 Thu, 19 Aug 2010 20:00:00 +0100 3885343 http://www.medworm.com/index.php?rid=3552548&cid=t_131465_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FMS-PTE-LQVU%2F Hello, everyone. Nice to see you again. Another shiny day here on the Pharmalot corporate campus where the grounds are being spruced up in a long overdue move. What will today bring? Important meetings and deadlines, no doubt. As you ready yourself, here are a few items to help you along. Best of luck and catch you later… Galapagos Widens Lung Drug Deal With Roche (Reuters) Drugmakers Leave New Jersey’s Medicine Chest Bare (NJ Spotlight) Purdue Files Patent Infringement Suit Against Ranbaxy (Business Standard) Merck And Glenmark Settle Zetia Patent Suit (Bloomberg News) UK Drug Shortages May Last Until 2011 (PharmaTimes) Proton Pump Inhibitors Increase Bone Fracture Risk (Los Angeles Times) Cost Of Treating Cancer Doubles (Associated Press) Roche Seeks Deal Approval In Accutane... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3552548 Tue, 11 May 2010 11:31:23 +0100 3552548 http://www.medworm.com/index.php?rid=2807838&cid=t_131465_136_f&fid=35294&url=http%3A%2F%2Fwww.psa-rising.com%2Fblog%2F2009%2F09%2Furologists-huddle-with-drug-companies-in-montreal-canada-meeting%2F the 4th C2 Academic Retreat (C2R) being organized jointly by the Canadian Urologic Oncology Group (CUOG) and the Canadian Urology Research Consortium (CURC) is scheduled for the weekend of September 25 to 27, 2009 at the fashionable hotel called W in Montreal. According to UroToday, “this three-day educational event will include provocative ‘Town Hall’ sessions [...] (Source: psa-rising.com/blog) psa-rising.com/blog blogs http://www.medworm.com/rss/comments.php?id=2807838 Fri, 18 Sep 2009 03:55:30 +0100 2807838 http://www.medworm.com/index.php?rid=2367355&cid=t_131465_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2Fearly-and-locally-advanced-breast-cancer-diagnosis-and-treatment%2F Title: Early and locally advanced breast cancer: diagnosis and treatment Source: NICE The Skinny: This guideline covers: some of the tests and treatments that patients with early and locally advanced breast cancer should be offered, in particular: – reducing the amount of surgery under your arm – breast reconstruction when breast conservation is not possible – chemotherapy and endocrine treatments – biological treatments. It does not specifically look at: the care of patients with advanced breast cancer or those with rare or non-cancerous tumours of the breast the care of people who do not have breast cancer themselves but have a family history of the disease. This guideline updates the following technology appraisals: TA107 Breast cancer (early) - trastuzumab (published Augu... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367355 Wed, 15 Apr 2009 09:38:01 +0100 2367355 http://www.medworm.com/index.php?rid=1969221&cid=t_131465_134_f&fid=36049&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FDiabetesNotes%2F%7E3%2FnclkDZjJgbY%2F var iamInit = function() {try{initIamServingHandler(420,297,269464,"http://cdn.pis.picapp.com/IamProd/Resources/Css/css2.css")}catch(ex){}}() Well this is super exciting news! “Two popular leukemia drugs, Gleevec and Sutent, kept lab mice from developing type 1 diabetes and put 80 percent of diabetic mice in remission, an international team said on Monday.” The mice that went into remission happened after 8-10 weeks on the drug. Can you imagine the potential for this? It could mean a cure is very close. But we’ve heard that several times over the last few years, so I won’t get (too) excited. Yet. The article further quotes that, “The fact that the treated mice maintained normal blood glucose levels for some time after the drug treatment was stopped suggests ... Diabetes Notes blogs http://www.medworm.com/rss/comments.php?id=1969221 Tue, 18 Nov 2008 13:35:46 +0100 1969221 http://www.medworm.com/index.php?rid=1769440&cid=t_131465_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F383877706%2F Conclusion My thanks to everyone that contributed articles — it’s been great hosting the Cancer Research Blog Carnival for a second time this year. Be sure to take a moment and let your fellow bloggers know this issue is available so that everyone’s hard work can be appreciated and enjoyed by all. The Cancer Research Blog Carnival is looking for future hosts. You can find both the hosting schedule and past editions at the Cancer Research Blog Carnival website. For more information on the U.S. investment in cancer research, you can read the NCI’s plan and budget proposal for fiscal year 2009. References Niederhuber JE. A look inside the National Cancer Institute budget process: implications for 2007 and beyond. Cancer Res. 2007 Feb 1;67(3):856-62. View abstract The ... Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1769440 Fri, 05 Sep 2008 04:49:31 +0100 1769440 http://www.medworm.com/index.php?rid=1679392&cid=t_131465_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D3922 We now know, due to the pioneering work of Warren and Marshall (the duo won the Nobel prize in Medicine in 2005) that Helicobacter pylori is the cause of most stomach ulcers. It has also been linked with stomach cancer. But will eradication of Helicobacter pylori prevent the development of stomach cancer? Previous trials in this area have shown inconclusive results. Recently, Japanese workers published work in The Lancet which shows that eradication of H. pylori has an impact on preventing recurrence of gastric cancer. The BBC reports: Patients with early stomach cancer underwent a procedure to remove the cancerous cells and surrounding tissue. Half of them were then treated with a course of drugs designed to eradicate H. pylori - lansoprazole, amoxicillin and clarithromycin - and half rec... Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=1679392 Mon, 04 Aug 2008 04:00:00 +0100 1679392 http://www.medworm.com/index.php?rid=1556545&cid=t_131465_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F323340828%2F Shocks it’s July and I am working out of the house. I barely made it through June…maybe it is time to get a new computer set? We’ll see… Anyways, here are a few stuff on cancer I might have missed in the recent days: ‘Designer baby’ to be free from breast cancer? Men’s cancer vaccine Accidental fungus leads to promising cancer drug That’s all for now folks..I gotta run! Tags: 'designer baby', accidental cancer drug, breast-cancer, cancer-drug, cancer-vaccine, free of hereditary breast cancer, fungus, Gardasil, men cancer vaccine, MerckShare This (Source: Cancer Commentary) Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=1556545 Mon, 30 Jun 2008 16:00:43 +0100 1556545 http://www.medworm.com/index.php?rid=1301914&cid=t_131465_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F251076162%2F An allergic reaction to the cancer drug cetuximab has been found. Sometimes the reaction includes anaphylaxis, a life-threatening condition characterized by a drop in blood pressure, fainting, difficulty breathing, and wheezing. Now researchers funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have discovered that specific pre-existing antibodies cause the severe reaction to the drug. Cetuximab is an immune-based therapy commonly used to treat persons diagnosed with head and neck cancer, or colon cancer, marketed as the popular brand Erbitux — a product of ImClone Systems Inc. and Bristol-Myers Squibb Company. Find more details from NIAD/NIH. Tags: allergic reaction, cancer-drug, cetuximab, colorectal-cancer, Erbit... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=1301914 Fri, 14 Mar 2008 00:19:39 +0100 1301914 http://www.medworm.com/index.php?rid=1156938&cid=t_131465_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHealth%2F%7E3%2F218040975%2F This article was published on Highlight HEALTH. Related articlesLack of Health Insurance Increases Risk of Cancer DeathDecrease in US Cancer DeathsThe Best of Highlight HEALTH 2007 - The Year in ReviewQuitWinLive - The Great American SmokeoutSmoking Duration vs. Intensity and the Impact on Lung Cancer Risk (Source: Highlight HEALTH) Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1156938 Thu, 17 Jan 2008 05:48:00 +0100 1156938 http://www.medworm.com/index.php?rid=2510405&cid=t_131465_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F09%2F14%2Feli-lillys-evista-cancer-drug-approved-by-fda%2F Filed under: Drug, All CancersIt's interesting when a drug is re-purposed into something aimed at fighting cancer, but that is what has happened to Evista, a prescription drug made by Eli Lilly which was originally for osteoporosis patients.The FDA has officially approved Evista for use in breast cancer patients as of late this week, although the drug will now come with a box warning advising patients of a heightened risk for stroke by taking the drug.I'm not sure -- are some drugs worth the possible benefits when certain side effects can be just as bad as what is trying to be treated?Read | Permalink | Email this | Linking Blogs | Comments (Source: The Cancer Blog) The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=2510405 Thu, 13 Sep 2007 23:00:00 +0100 2510405 http://www.medworm.com/index.php?rid=733624&cid=t_131465_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F07%2F13%2Fmerck-and-ariad-to-team-no-new-cancer-drug%2F Filed under: Drug, All CancersIt appears pharmaceutical giant Merck is wanting to get a larger piece of the cancer drug pie. The company iaspartnering with Ariad Pharmaceuticals to develop a new cancer treatment (in an experimental stage) with the potential to make the smaller Ariad over a billion greenbacks.Genentech's Avastin has been selling like hotcakes lately, and the world is sure to see a slew of new-generation cancer drugs by 2010 if my crystal ball is correct. Right now, Ariad's experimental cancer drug -- known as 'AP23573' -- is helping define a new category of cancer drugs that block certain proteins and effectively "starve" cancer cells.To the delight of both Ariad and Merck, AP23573 is on "fast track" mode for a quicker review (and most likely, approval) and it's also been s... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=733624 Fri, 13 Jul 2007 04:00:00 +0100 733624 http://www.medworm.com/index.php?rid=579293&cid=t_131465_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F04%2F30%2Ftoenail-fungal-drug-can-block-angiogenesis%2F Filed under: Drug, All Cancers, Research, Daily newsResearchers at Johns Hopkins discovered that a drug commonly used to treat toenail fungus could block angiogenesis, blood vessels that feed a tumor. The drug, itraconazole, is FDA approved for human use, which may fast-track its availability as an anti-cancer drug. If you are interested in reading more about Angiogenesis and cancer growth you can read my post back in July. The researchers at this point have yet to determine exactly how itraconazole works to stop vessel growth. Read | Permalink | Email this | Linking Blogs | Comments (Source: The Cancer Blog) The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=579293 Mon, 30 Apr 2007 04:00:00 +0100 579293 http://www.medworm.com/index.php?rid=566338&cid=t_131465_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F04%2F24%2Ffound-four-genes-that-spread-breast-cancer-to-lungs%2F Filed under: Breast Cancer, Research, Daily newsA new study of mice implanted with human breast cancer cells shows the spread of the disease to the lungs -- a common metastasis site -- is caused by the abnormal activation of four specific genes working together.The study, published in the journal Nature, indicates that shutting off the genes one by one can slow the growth and spread of this cancer. But turning off all four at one time almost completely stops the process. In mice anyway.These genes are no strangers to researchers who have known for some time about their existence and functions. They just know more about them now.The four genes work together at every step of the metastatic process to allow a breast tumor to develop blood vessels, let tumor cells enter the vessel walls and lu... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=566338 Tue, 24 Apr 2007 04:00:00 +0100 566338