MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'cancer stem cell'. Sat, 03 Sep 2011 02:21:42 +0100 http://www.medworm.com/index.php?rid=4424396&cid=t_141049_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2011%2F01%2F31%2Fyale-university-scientists-synthesize-long-sought-after-anticancer-agent%2F A team of Yale University scientists has synthesized for the first time a chemical compound  called “lomaiviticin aglycon, ” which led to the development of a new class of molecules that appear to target and destroy cancer stem cells. A team of Yale University scientists has synthesized for the first time a chemical compound called [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=4424396 Tue, 01 Feb 2011 07:25:18 +0100 4424396 http://www.medworm.com/index.php?rid=4190208&cid=t_141049_106_f&fid=36682&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FSutureForALiving%2F%7E3%2FWU2DY-YNwLo%2Frisks-of-fat-grafting-in-breast-cancer.html Fat grafting as a means of either (cosmetically) enlarging breasts or (reconstructively) correcting defects / asymmetries after breast cancer surgery/radiation therapy has been gaining ground as an acceptable method in the past few years.  True, much debate is still occurring but research is being encouraged to answer questions regarding safety (short and long-term) and efficacy. The two articles (full references below) from researchers at the University of Pittsburgh School of Medicine suggests that it is NOT safe to use adipose-derived stem cells (ADSC) that may be part of fat grafting in any patient with active tumor cells.  From the first article’s abstract (bold emphasis is mine): Adipose-derived stem cells (ASCs) have been proposed to stabilize autologous fat grafts fo... Suture for a Living blogs http://www.medworm.com/rss/comments.php?id=4190208 Mon, 22 Nov 2010 12:15:00 +0100 4190208 http://www.medworm.com/index.php?rid=4134164&cid=t_141049_136_f&fid=39026&url=http%3A%2F%2Fcarolinemfr.blogspot.com%2F2010%2F11%2Finteresting-adventure.html Cancer relapse or the 'Cancer Sleeper Cell' are oh-so-reassuring (NOT!). I read this article and paid attention to it - through all five pages. So they are now trying to figure out if cancer has its own stem cells. But they haven't quite figured it out yet. They are trying. They have been working in this area since at least 1974 - so in 36+ years they still aren't sure.On one level its quite interesting and almost exciting that they are looking at cancer down at the cell level to see which ones are stem cells - capable of regenerating themselves. They are this deep into cancer biology that they are looking at it cell by cell, detail by detail. They can define different kinds of cells and know which ones they should treat differently.On the other hand, its been more than 36 years so this mu... Caroline's Breast Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=4134164 Wed, 03 Nov 2010 10:25:00 +0100 4134164 http://www.medworm.com/index.php?rid=2424420&cid=t_141049_136_f&fid=36070&url=http%3A%2F%2Fnetwork.nature.com%2Fpeople%2Fbasanta%2Fblog%2F2009%2F05%2F20%2Fwhy-dont-tumours-grow-in-muscles I am currently in Trento, Italy, visiting CoSBI, the Microsoft/University of Trento Centre for Computational and Systems Biology and while preparing my own talk I decided to look for inspiration watching a couple of TED talks talks. I got more than what I bargained for. One that caught my attention was a rather brief one by a very young scientist, Eva Vertes. Her talk was entitled My dreams about the future of medicine but more than a view on the future of medicine the talk was about something quite relevant to me. Her question was why does cancer arise in tissues like the prostate, the breast, the brain, etc but not in the heart or the skeleton muscle?. She makes other interesting points like assuming that all cancers are the results of stem cells (which would surprise me if it were true)... Cancerevo: Evolution and cancer blogs http://www.medworm.com/rss/comments.php?id=2424420 Wed, 20 May 2009 06:36:10 +0100 2424420 http://www.medworm.com/index.php?rid=2013937&cid=t_141049_136_f&fid=36162&url=http%3A%2F%2Fmyelomablog.com%2F2008%2F12%2F04%2Fsend-positive-thoughts%2F I’ve been writing to Suleyman, who is in the Netherlands and is undergoing an allo stem cell transplant to treat and hopefully cure his leukemia.  He had to undergo some high dose chemo (busulfan and cyclophosphamide). He’s having a rough time, so he needs some healing thoughts sent his way.  The stem cells from his brother will take about three weeks to engraft.  I hope I can get him to send a picture! (Source: beth's myeloma blog) beth's myeloma blog blogs http://www.medworm.com/rss/comments.php?id=2013937 Thu, 04 Dec 2008 23:28:33 +0100 2013937 http://www.medworm.com/index.php?rid=810000&cid=t_141049_107_f&fid=36045&url=http%3A%2F%2Fbayblab.blogspot.com%2F2007%2F08%2Fstem-cell-delusion-are-they-still-stem.html On a previous episode of the bayblab podcast, I argued (rather poorly) that so-called mammalian "stem" cells are not so magical and deterministic as we think (ie they do not "exist"). Rather, I attempted to argue, the stem cell illusion is an emergent property of fundamental cell population dynamics and is even exhibited by the lowly unicellular prokaryotes, as exemplified by the phenomenon of bacterial persistence. A new PLOSone paper explores the theoretical basis of bacterial persistence as population bet-hedging:"Within a population of bacteria there exists a subgroup of cells that do not grow at the normal rate but exists in a quiescent, non-growing or slow-growing state. These cells are sometimes called persister cells [1], because they are able to persist in the face of catastrophic... Bayblab blogs http://www.medworm.com/rss/comments.php?id=810000 Fri, 17 Aug 2007 04:52:00 +0100 810000 http://www.medworm.com/index.php?rid=810006&cid=t_141049_107_f&fid=36045&url=http%3A%2F%2Fbayblab.blogspot.com%2F2007%2F08%2Fcreating-cancer-stem-cells.html Ok maybe I'm thick, but this latest paper still doesn't make it clear to me that static cancer stem cells exist. A team at MIT has developed a kind of media that promotes the growth of cancer stem cells. When growing identical breast tissue samples in normal or "special" media and then transforming them with the same oncogene, two types of cells are formed. Each line produced different tumours when xenografted, with the cells growing in the "special" media forming more agressive, metastasis prone cancers. Furthermore those special cells were 4 orders of magnitude more likely to form tumours (i.e. it took 10^4 less cells). The researchers concluded that they had a found a way to make cancer stem cells.Lets get back to the definition of cancer stem cell: it's a cell which has the ability to ... Bayblab blogs http://www.medworm.com/rss/comments.php?id=810006 Thu, 16 Aug 2007 01:30:00 +0100 810006