MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'carcinoma'. Sat, 03 Sep 2011 02:00:48 +0100 http://www.medworm.com/index.php?rid=5159877&cid=t_105639_155_f&fid=38410&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FOncopathology%2F%7E3%2FctuWglwyQno%2Fprotocolfor-of-breast-diagnosis-of.html Protocol for Synpotic reporting of Breast  excision specimen with diagnosis of  Ductal Carcinoma In Situ (DCIS) of the Breast Protocol applies to DCIS without invasive carcinoma or microinvasion. The complete pathology report should include following parameters. Specimen type. ___ Partial breast ___ Total breast (including nipple and skin) ___ Other (specify):  ___ Not specified Procedure  ___ Excision without wire-guided localization ___ Excision with wire-guided localization ___ Total mastectomy (including nipple and skin) ___ Other (specify): ____________________________ ___ Not specified Lymph Node Sampling (select all that apply)  ___ No lymph nodes present ___ Sentinel lymph node(s) ___ Axillary disse... Oncopathology blogs http://www.medworm.com/rss/comments.php?id=5159877 Thu, 25 Aug 2011 21:27:00 +0100 5159877 http://www.medworm.com/index.php?rid=5125976&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2011%2F08%2Fwclc-2011-oral-presentations-squamous-cell-carcinoma.html This study involved a tissue microarray constructed from 568 patients with stage 1 NSCLC with detailed histopathological and clinical data.  SOX2 gene data was determined by FISH and SOX2 protein expression was assessed by IHC.  This data was correlated then with clinicopathological findings and OS and cancer-specific survival. Increased SOX2 gene amplification or polysomy was found in 4% of (17/429) evaluable samples but 16/17 (94%) were associated with non-ADC histology.  SOX2 protein expression was found in 48% of NSCLC and was associated with non-ADC histology (P<0.001): SOX2 expression was identified in 78% of SQC specimens (178/227) but only in 15% of ADC (29/191).  Further, SOX2 protein expression was significantly associated with high grade tumors, patien... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=5125976 Fri, 12 Aug 2011 12:05:00 +0100 5125976 http://www.medworm.com/index.php?rid=5119013&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2011%2F08%2Fwclc-2011-summary-from-plenary-session.html There were three themes from the Monday, July 3 plenery session at the 2011 14th World Conference on Lung Cancer.  First, the effect of smoking cessation on lung cancer incidence was discussed in relation to a recent study showing that women who smoke 20 cigarettes a day have a risk of developing lung cancer 30 times higher than non-smokers.  However, the study also showed that quitting before age 50 reduced the risk to sic times higher and quitting before age 40 reduced it to 1.2 times higher almost completely eliminating the risk from smoking. The second major theme discussed the shift from squamous cell carcinoma (SQC) to adenocarcinoma (ADC) as the most prevalent histologic type of lung cancer.  The development of cigarette filters was discussed as one reason for this... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=5119013 Wed, 10 Aug 2011 20:30:00 +0100 5119013 http://www.medworm.com/index.php?rid=5035787&cid=t_105639_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FVa5oMI-q_js%2F Hosts: Vincent Racaniello, Rich Condit, and Alan Dove Vincent, Rich, and Alan discuss a method for identifying viruses of individual environmental bacteria, and the using a picornavirus for oncotherapy. Click the arrow above to play, or right-click to download TWiV 142 (69 MB .mp3, 95 minutes). Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Probing individual bacteria for their viruses (Science) Looking in vivo at virus-bacterium interactions (ScienceDaily) Integrated fluidic circuit (Fluidigm) Oncotherapy with Seneca Valley Virus (Clin Cancer Res) Epidemiology of Seneca Valley virus (pdf) Senecavirus at ViralZone Small cell lung cancer (NCBI) ECOG performance st... virology blog blogs http://www.medworm.com/rss/comments.php?id=5035787 Sun, 17 Jul 2011 12:30:20 +0100 5035787 http://www.medworm.com/index.php?rid=4992689&cid=t_105639_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2F5-important-reasons-to-protect-your-eyes-from-the-suns-uv-radiation%2F2011.07.01 A Pterygium Dermatologists have done a great job promoting sun safety. We all know that we should use sunscreen or sunblock to avoid burns, and to reapply it religiously when we plan to be outdoors for long periods of time. But how often do we think about protecting our eyes from the same UV rays? A dear friend of mine has been on a long-term medicine that makes her skin especially sun-sensitive. She did not take sufficient precautions to protect her eyes from UV radiation (though she always wore sunscreen on her skin), and she developed a pterygium that looks just like the photograph above. Her condition reminded me of the importance of eye protection, and I thought I’d offer you 5 excellent reasons to start shielding your eyes from the sun. UV protection is critical for avoiding: 1... Better Health blogs http://www.medworm.com/rss/comments.php?id=4992689 Fri, 01 Jul 2011 18:00:52 +0100 4992689 http://www.medworm.com/index.php?rid=4795068&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2011%2F05%2Fddr2-kinase-mutations-in-lung-squamous-cell-carcinoma.html Yes--you read that right! The journal Cancer Discovery reports in a publish ahead-of-print article (abstract)the discovery of mutations in the discoidin domain receptor 2 tyrosine kinase (DDR2) gene in a series of lung squamous cell carcinomas (SQC) that may identify a  potential therapeutic target similar to those described for lung adenocarcinomas.  Interestingly, DDR2 is a receptor kinase that normally binds collagen as its ligand and has been shown to promote cell migration, proliferation, and survival when activated by ligand binding and phosphorylation. While subtypes of lung adenocarcinoma (ADC) have been increasingly better defined and characterized on multiple levels with respect to identifying therapeutic targets/responses, minimal progress has been made with squamous... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=4795068 Fri, 06 May 2011 16:40:35 +0100 4795068 http://www.medworm.com/index.php?rid=4684777&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2011%2F04%2Faberrant-wnt1-and-beta-catenin-expression-in-nsclc.html This month's April 2011 Journal of Thoracic Oncology has an interesting paper by Xu and colleagues (abstract) that examines Wnt1 expression in non-small cell lung cancer (NSCLC) in relation to downstream Wnt signaling molecules, including beta-catenin, and correlates different marker expression with traditional clinicopathological parameters. This is an immunohistochemical study of a tissue microarray composed of 262 NSCLC resected specimens.    The authors define aberrant beta-catenin expression as: 1) decreased membranous pattern in less than 70% of tumor cells, 2) cytoplasmic pattern of expression, or 3) nuclear pattern of expression.  As expected, the majority of patients are stage 1 or 2 but nearly 36% of the study population are never-smokers--over 50% in ... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=4684777 Tue, 05 Apr 2011 19:55:50 +0100 4684777 http://www.medworm.com/index.php?rid=4298808&cid=t_105639_155_f&fid=38410&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FOncopathology%2F%7E3%2FFsQnflY9WE8%2Fbreast-carcinoma-vs-pulmonary.html Some authors have estimated that 4-9% of patients with breast carcinoma will eventually develop second pulmonary carcinomas. As a result, many pathologists have been faced with the problem of trying to determine whether a particular lung carcinoma represents metastatic breast carcinoma or a new primary pulmonary adenocarcinoma. This month, we will briefly review antibodies that may be useful in addressing this differential diagnostic problem. GCDFP-15 (gross cystic disease fluid protein-15): This marker has good specificity for breast carcinoma, although its sensitivity is not high, as only about 50% of breast carcinomas express this marker. Another potential problem with this marker (particularly when dealing with small biopsy specimens) is that it is often expressed in a focal ... Oncopathology blogs http://www.medworm.com/rss/comments.php?id=4298808 Thu, 30 Dec 2010 03:51:00 +0100 4298808 http://www.medworm.com/index.php?rid=4275599&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F12%2Foptimal-panel-for-differentiating-nsclc-in-small-specimens.html This study makes several practical points that can be nicely summarized as bullets: For ADC the most sensitive marker and best negative predictor is CK7: 93% sensitivity, 91% NPV. For ADC the most specific marker and best positive predictor is Napsin A: 94% specificity, 90% PPV. TTF-1 has similar specificity as Napsin A for ADC. For SQC the most sensitive marker and best negative predictor is p63: 84% sensitivity, 86% NPV. For SQC the most spepcific marker and best positive predictor is NTKR2 (a neurotrophic tyrosine kinase receptor, rarely used outside of research labs) but CK5/6 has a nearly identical specificity and PPV: about 95% specificity, about 95% PPV. No single marker is BOTH highly sensitive and specific for either ADC or SQC. The authors identified a 6-marker panel that inclu... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=4275599 Tue, 21 Dec 2010 12:22:00 +0100 4275599 http://www.medworm.com/index.php?rid=4175981&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F11%2Fassociation-between-egfr-mutations-and-ercc1-expression-in-nsclc.html Gandara and colleagues from UC Davis Cancer Center have published ahead-of-print on October 21, 2010 in Journal of Thoracic Oncology an interesting article examining the association between EGFR activating mutations and ERCC1 gene expression in NSCLC. NSCLC tumors that show EGFR activating mutations are also more likely to show low expression of ERCC1 mRNA levels according to this study.  This might explain (at least in part) the clinical observation that suggest enhanced efficacy of platinum-based chemotherapy in patients with EGFR-mutant NSCLCs. The authors performed microdissection of tumors from 1207 patients with NSCLC and analyzed EGFR mutation by allele-specific by PCR and ERCC1 mRNA expression by RT-PCR. Median ERCC1 expression was histology-related: adenocarcinoma (ADC... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=4175981 Wed, 17 Nov 2010 12:04:00 +0100 4175981 http://www.medworm.com/index.php?rid=4164490&cid=t_105639_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2010%2F11%2Fage-distribution-adrenal-carcinoma%2F Although usually thought of as a condition presenting in the 5th and 6th decade of life, adrenal carcinoma actually has a bimodal age distribution, wtih the incidence increasing in the first decade and then again between 40 and 50 years of age. In children it can present with hypertension, pubic hair, and genital enlargement or in girls virilization. The optimal treatment is always surgery. (Source: Inside Surgery) Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=4164490 Sun, 14 Nov 2010 07:41:44 +0100 4164490 http://www.medworm.com/index.php?rid=4086528&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F10%2Fa-little-bit-more-about-bac-of-lung.html Literally within minutes of publishing my previous post following up on a digital case challenge on bronchioloalveolar carcinoma (BAC) of the lung, I discover this month's (October 2010) Archives of Pathology and Laboratory Medicine on my desk which contains a nice article by Lindsay Schmidt and Jeffrey Myers titled, "Bronchioloalveolar Carcinoma and the Significance of Invasion: Predicting Biologic Behavior" (Arch Pathol Lab Med 2010;134:1450-1454). The issue is how to designate tumors that show stromal invasion but are mostly BAC (think Miracle Max from The Princess Bride: "It just so happens that your friend here is only MOSTLY dead. There's a big difference between mostly dead and all dead.").  Ah, but how much is mostly?  This ... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=4086528 Wed, 20 Oct 2010 10:56:00 +0100 4086528 http://www.medworm.com/index.php?rid=4036956&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F10%2Ffollow-up-on-adenocarcinoma-with-bac-features.html My last post was a "Digital Case Challenge" presenting a case of pulmonary adenocarcinoma with non-mucinous bronchioloalveolar (BAC) features. Here's my synopsis of 3 recent papers on bronchioloalveolar carcinoma that focus on the clinicopathological, histological, and molecular differences between the two subtypes, non-mucinous and mucinous, as well as the practical importance in distinguishing these two subtypes. 1.  Wislez et al, in a recently published paper in Lung Cancer (2010;68:185-191), studied 50 cases of non-resectable adenocarcinoma with bronchioloalveolar (ADC-BAC) features who were enrolled in a multicenter study to evaluate gefitinib as a first-line therapy for non-resectable ADC-BAC.  Previous trials (SWOG S0126 and IFCT0401) have shown that ... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=4036956 Wed, 06 Oct 2010 21:13:32 +0100 4036956 http://www.medworm.com/index.php?rid=4031515&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F09%2Fdigital-case-challenge-non-mucinous-bronchioloalveolar-adenocarcinoma.html It has been a long while since I've posted one of the cases I've worked on and now its time to clear off my desk (before our CAP inspection). The patient is an 83-year-old white man, non-smoker, who presented 2 months prior to surgery with cough and shortness-of-breath and was found to have a left lower lobe infiltrate and pleural effusion.  After hospital admission and a course of antibiotics, the patient's symptoms initially improved.  However, he returned again about one month later with the same symptoms and persistent infiltrate.  Bronchoscopy revealed a mass-like lesion but cytologic studies were negative.  He underwent CT-guided biopsy of the infiltrate which showed adenocarcinoma.  He subsequently underwent lobectomy and that specimen showe... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=4031515 Tue, 05 Oct 2010 14:58:42 +0100 4031515 http://www.medworm.com/index.php?rid=3807528&cid=t_105639_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F07%2Fmrna-subtypes-in-lung-squamous-cell-carcinoma.html With all the recent studies looking at various distinct histological and molecular subtypes in lung adenocarcinoma, lung squamous cell carcinoma has been somewhat neglected.  Pathologists have recognized variability in morphological appearances in squamous cell carcinomas and there is a wide range of clinical outcomes.  Although the recent WHO classification recognizes four uncommon histological variants, their biological and clinical significance is not clear.  Moreover, clinical differences between other less-defined morphological patterns are unknown.A paper published online on July 19, 2010 on Clinical Cancer Research by Wilkerson et al. from University of North Carolina sheds a new light of lung squamous cell carcinoma (abstract).  They describe four novel repr... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=3807528 Sat, 31 Jul 2010 14:19:12 +0100 3807528 http://www.medworm.com/index.php?rid=3746687&cid=t_105639_87_f&fid=34872&url=http%3A%2F%2Fblisstree.com%2Ffeel%2F187954%2F Link Between HPV and Skin Cancer: A new study suggests that the risk for developing squamous cell carcinoma is higher if you have HPV, especially if you’re taking drugs like glucocorticoids to suppress the immune system. (via US News and World Report) Post from: BlissTree (Source: Healthbolt) Healthbolt blogs http://www.medworm.com/rss/comments.php?id=3746687 Fri, 09 Jul 2010 18:40:16 +0100 3746687 http://www.medworm.com/index.php?rid=3635504&cid=t_105639_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Fwww.twiv.tv%2FTWiV085.mp3 Hosts: Vincent Racaniello and Michael Gale On episode 85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses. This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo. Download TWiV #85 (40 MB .mp3, 56 minutes) Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio. Links for this episode: The Gale Laboratory at the University of Washington Incredible view from the Gale laboratory (jpg) Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review) New potent HCV inhibitor HCV virion and genome s... virology blog blogs http://www.medworm.com/rss/comments.php?id=3635504 Sun, 06 Jun 2010 15:33:31 +0100 3635504 http://www.medworm.com/index.php?rid=3538091&cid=t_105639_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fa-science-based-view-of-the-complexity-of-cancer%2F2010.05.06 [Recently] I participated in a panel discussion at the Northeast Conference of Science and Skepticism (NECSS) with John Snyder, Kimball Atwood, and Steve Novella, who also reported on the conference. What I mentioned to some of the attendees is that I had managed to combine NECSS with a yearly ritual that I seldom miss, namely the yearly meeting of the American Association for Cancer Research (AACR) meeting. There are two huge cancer meetings every year — AACR and the annual meeting of the American Society for Clinical Oncology (ASCO). AACR is the meeting dedicated to basic and translational research. ASCO, as the word “clinical” in its name implies, is devoted mainly to clinical research. Personally, being a translational researcher myself and a surgeon, I tend to prefer the ... Better Health blogs http://www.medworm.com/rss/comments.php?id=3538091 Thu, 06 May 2010 12:00:09 +0100 3538091 http://www.medworm.com/index.php?rid=3526355&cid=t_105639_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Fwww.twiv.tv%2FTWiV080.mp3 Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Michael Bouchard Vincent, Alan, and Rich speak with Michael Bouchard about hepatitis B virus discovery, replication, and pathogenesis. This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo. Win a free Drobo S! Contest rules here. Download TWiV #80 (58 MB .mp3, 80 minutes) Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email. Links for this episode: The enigmatic X gene of hepatitis B virus Tableau public (thanks Ricardo!) Molecular phylogeny of Archaea from soil (thanks Etienne!) Habitats of Archaea (thanks Cedric!) Timer remote controls (thanks Bill!) Letters read in episode 80 Weekly Science Picks Rich PBS Frontline: The Vaccine War Alan ... virology blog blogs http://www.medworm.com/rss/comments.php?id=3526355 Mon, 03 May 2010 00:39:31 +0100 3526355 http://www.medworm.com/index.php?rid=3519554&cid=t_105639_115_f&fid=34670&url=http%3A%2F%2Fsumerdoc.blogspot.com%2F2010%2F04%2Fcarcinoma-stomach-with-peritoneal.html Note the antropyloric mass with peritoneal deposits.From Sumer's Radiology Site http://www.sumerdoc.blogspot.com -The Top Radiology Magazine. Teleradiology Providers at www.teleradproviders.com Mail us at teleradproviders@gmail.com (Source: Sumer's Radiology Site) Sumer's Radiology Site blogs http://www.medworm.com/rss/comments.php?id=3519554 Fri, 30 Apr 2010 09:38:00 +0100 3519554 http://www.medworm.com/index.php?rid=3468045&cid=t_105639_155_f&fid=38410&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FOncopathology%2F%7E3%2FVhQmIUgOzag%2Fmicrocystic-adenocarcinoma-of-prostate.html Reference :Microcystic Adenocarcinoma of the Prostate: A Variant of Pseudohyperplastic and Atrophic Patterns : Yaskiv, Oksana et al.The American Journal of Surgical Pathology: April 2010 - Volume 34 - Issue 4 - pp 556-561Do you see anything in this prostate that's worrisome for malignancy? dilated glands admixed with small acini in a noduleI don't, at least not at this power, and yet this is an example of "microcystic" adenocarcinoma of the prostate. Higher power will show clear-cut cytologic features of malignancy.If this doesn't concern you about the risk of scanning prostate slides at 4x, it should!Microcystic adenocarcinoma with dilated and crowded glands displaying a predominantly flat lining layerMicrocystic adenocarcinoma with jumbled arrangement of dilated malignant glands.Microcys... Oncopathology blogs http://www.medworm.com/rss/comments.php?id=3468045 Tue, 13 Apr 2010 20:43:00 +0100 3468045 http://www.medworm.com/index.php?rid=3408632&cid=t_105639_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FLiUgnNH3qCw%2F Here’s the connection: the human papillomavirus, which can cause cervical cancer, is also linked to head and neck cancer, including one form called oropharyngeal squamous cell carcinoma, or OSCC, which is spread by oral sex, according to a piece in BMJ. And more cases, particularly in the developing world, are being reported, and so the BMJ researchers suggest wider use of HPV vaccines should be explored - for boys as well as girls. “We need to look at the evidence again to re-evaluate the cost-effectiveness of male children in light of this new and rapidly rising incidence,” Hisham Mehanna of the Institute of Head and Neck Studies at University Hospital Coventry, one of the BMJ researchers, told Reuters. Currently, however, the HPV vaccines - Merck’s Gardasil and G... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3408632 Fri, 26 Mar 2010 12:57:33 +0100 3408632 http://www.medworm.com/index.php?rid=2966799&cid=t_105639_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F11%2Febv-nuclear-antigen-family-3.html Epstein-Barr virus (EBV) infects over 90% of the world's population, and like other herpesviruses it establishes a permanent latent infection in the host. The native B-lymphocyte is the preferred target of EBV, which after differentiation into memory B-cells contains the latent reservoir of virus subsequent to the resolution of acute infection. Several malignancies have been associated with EBV infection, including nasopharyngeal carcinoma, endemic Burkitt's lymphoma, AIDS-related lymphoma and post-transplant lymphoproliferative disorder, among others. During the latent phase of infection and in EBV-associated tumors, a limited number of viral proteins are expressed, among them the Epstein-Barr nuclear antigen 3 (EBNA3) family of proteins. Of these three proteins, two (EBNA3A and 3C) are a... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2966799 Fri, 06 Nov 2009 09:23:00 +0100 2966799 http://www.medworm.com/index.php?rid=2593220&cid=t_105639_136_f&fid=35300&url=http%3A%2F%2Fwww.metastaticlivercancer.org%2F2009-06-15-cancer-treatment%2Fsmall-cell-carcinoma-of-the-lungs%2F What do you do when your oncologist gives you a small cell lung cancer prognosis of 6 months with chemotherapy and half as long without chemotherapy?   Gary wants to know. Please share your experience like we share ours.   Small cell lung cancer prognosis and secondary liver cancer   As far as I have experienced: as soon as doctors and oncologists hear "secondary liver cancer", they reason that:   "with a normal effort" there is no cancer treatment.   We stress "with normal effort". With a huge extra effort and doing everything right, our few secondary cancer survivors are living proof that you can survive secondary liver cancer much longer than the prognosis done in your hospital.   If you want to go the "do everything rig... Metastatic liver cancer blogs http://www.medworm.com/rss/comments.php?id=2593220 Mon, 15 Jun 2009 08:09:21 +0100 2593220 http://www.medworm.com/index.php?rid=3416368&cid=t_105639_155_f&fid=38410&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FOncopathology%2F%7E3%2FVOo1wd6vvek%2Fpathologic-work-up-of-carcinoma-of.html It is often important to determine the site of origin of a metastatic carcinoma of unknown primary site, particularly because this may affect the choice of the treatment. Determination of the primary site may take several steps.Clinical features, such as age, sex, and site of metastases may give a first indication.A detailed pathologic examination of the most accessible biopsied tissue specimen is mandatory in CUP cases. Pathologic evaluation typically consists of hematoxylin-and-eosin stains and immunohistochemical tests. Electron microscopy is rarely used currently, although it may beselectively useful when making treatment decisions.Role of Serum Tumor Markers and CytogeneticsMost tumor markers, including CEA, CA-125, CA 19-9, and CA 15-3, when elevated, are nonspecific and not helpful ... Oncopathology blogs http://www.medworm.com/rss/comments.php?id=3416368 Mon, 04 May 2009 14:45:00 +0100 3416368 http://www.medworm.com/index.php?rid=2387244&cid=t_105639_155_f&fid=38410&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FOncopathology%2F%7E3%2F6KV0hVhepGs%2Fpathologic-work-up-of-carcinoma-of.html It is often important to determine the site of origin of a metastatic carcinoma of unknown primary site, particularly because this may affect the choice of the treatment. Determination of the primary site may take several steps. Clinical features, such as age, sex, and site of metastases may give a first indication. A detailed pathologic examination of the most accessible biopsied tissue specimen is mandatory in CUP cases. Pathologic evaluation... This is the content of summary only. Please visit www.oncopathology.blogspot.com for complete details. Thank you. (Source: Oncopathology) Oncopathology blogs http://www.medworm.com/rss/comments.php?id=2387244 Mon, 04 May 2009 14:45:00 +0100 2387244 http://www.medworm.com/index.php?rid=2218537&cid=t_105639_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2009%2F02%2F25%2Fsometimes-more-is-less-evaluation-of-experimental-platinum-based-treatment-regimens-in-advanced-stage-ovarian-cancer-a-phase-iii-trial-of-the-gynecologic-cancer-intergroup%2F “… Compared with standard paclitaxel and carboplatin, addition of a third cytotoxic agent [gemcitibine, liposomal doxorubicin or topotecan] provided no benefit in PFS [progression-free survival] or OS [overall survival] after optimal or suboptimal cytoreduction. Dual-stage, multiarm, phase III trials can efficiently evaluate multiple experimental regimens against a single reference arm. The development of new interventions [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=2218537 Wed, 25 Feb 2009 23:36:44 +0100 2218537 http://www.medworm.com/index.php?rid=2078803&cid=t_105639_136_f&fid=35300&url=http%3A%2F%2Fwww.metastaticlivercancer.org%2F2009-01-05-cancer-treatment%2Fliver-cancer-treatments%2F All liver cancer treatments explained clearly. Starting from which 3 types of liver cancer exist, causes of primary liver cancer and hepatitis b and c prevention.   We explain all curative liver cancer treatment options and when they are used: resection, liver transplantation, PEI, RF, cryoablation, chemotherapy, radiotherapy and chemoembolisation.   Liver Cancer   There are 3 very different kind of liver cancers to consider:   1. Metastatic liver cancer     (father’s metastatic liver cancers like raisins in a raisin bread)   Also called secondary liver cancer is a cancer that started in another organ (colon, pancreas, stomach, lung or breast) and is now growing in the liver as well.   A cancer that started in the liver therefore is called ... Metastatic liver cancer blogs http://www.medworm.com/rss/comments.php?id=2078803 Sun, 04 Jan 2009 16:00:22 +0100 2078803 http://www.medworm.com/index.php?rid=1886433&cid=t_105639_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F7AGPP4X5_9o%2F Traditionally, it is difficult to predict whether a cancer will recur, but recently biomarkers have been increasingly used that predict the recurrence of disease such as in prostate or bladder cancer, or chances of survival as in breast cancer. Another milestone has recently been reached, this time with liver cancer - a genetic signature has been identified that predicted whether a liver tumor is likely to occur. A signature made of 186 genes were found by an international team of scientists by probing the gene expression of 6,000 human genes. Correlating the gene expression of some 6,000 human genes with the recurrence at least two years after surgery, and also survival, led to a list of 186 genes as the probable signature for liver cancer recurrence. The team still have to validate the... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1886433 Sat, 18 Oct 2008 06:27:51 +0100 1886433 http://www.medworm.com/index.php?rid=1730740&cid=t_105639_136_f&fid=35300&url=http%3A%2F%2Fwww.metastaticlivercancer.org%2F2008-08-25-cancer-treatment%2Favastin-for-metastatic-liver-cancer%2F What can Avastin do in the treatment of metastatic liver cancer? Reading the avastin.com website says that Avastin in combination with intravenous 5FU based chemotherapy is indicated for first- or second-line treatment of patients with metastatic carcinoma of the colon or rectum.   In other words: it’s added to the 5FU chemotherapy cocktail, 5FU that father’s oncologist wanted to give father to treat his metastatic liver cancer. But the oncologist advised father to consider not to undergo 5FU (see Fu like in F… you!) treatment because:   at the age of 75 and in a weak condition due to the cancer, father could not survive the treatment  the chemotherapy side-effects could really spoil father’s quality of life in the few extra months the chemotherapy... Metastatic liver cancer blogs http://www.medworm.com/rss/comments.php?id=1730740 Mon, 25 Aug 2008 08:22:59 +0100 1730740 http://www.medworm.com/index.php?rid=1700567&cid=t_105639_115_f&fid=34670&url=http%3A%2F%2Fsumerdoc.blogspot.com%2F2008%2F08%2Fcarcinoma-stomach-with-krukenberg.html Dr.Sumer K Sethi, MDSr Consultant Radiologist ,VIMHANS and CEO-Teleradiology Providers Editor-in-chief, The Internet Journal of Radiology Director, DAMS (Delhi Academy of Medical Sciences) From Sumer's Radiology Site http://www.sumerdoc.blogspot.com -The Top Radiology Magazine. Mail us at teleradproviders@gmail.com (Source: Sumer's Radiology Site) Sumer's Radiology Site blogs http://www.medworm.com/rss/comments.php?id=1700567 Wed, 13 Aug 2008 10:01:00 +0100 1700567 http://www.medworm.com/index.php?rid=1727808&cid=t_105639_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2008%2F07%2F21%2Ftp53-gene-mutation-found-in-80-of-high-grade-ovarian-serous-carcinomas-tp53-not-directly-involved-in-the-development-of-drug-resistance%2F “… [T]he [Johns Hopkins] research team concluded that the frequency of TP53 gene mutations using purified tumor DNA from ovarian serous carcinomas was 80.3%, which is much higher than previously reported in the medical literature. Furthermore, the research team found that TP53 is not directly involved in the development of drug resistance in high-grade ovarian [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=1727808 Tue, 22 Jul 2008 05:42:32 +0100 1727808 http://www.medworm.com/index.php?rid=1622242&cid=t_105639_136_f&fid=35300&url=http%3A%2F%2Fwww.metastaticlivercancer.org%2F2008-07-15-cancer-treatment%2Fhow-do-you-prevent-liver-cancer%2F Since there is no miracle liver cancer treatment, you better read our answers about how do your prevent liver cancer. Liver cancer is the most common cancer in the world. It is also the third leading cause of cancer-related deaths worldwide. You might enjoy the stories of cancer survivors, but reality is bitter. The prognosis for HCC is never good with a liver cancer survival rate of less than a year. It may be impossible to prevent metastatic liver cancer, but there are possibilities of reducing the risks of getting primary liver cancer… or so says the medical world:   Maintaining a healthy lifestyle and getting the Hepatitis B vaccine is the most effective way of preventing liver cancer   There are 2 parties involved in maintaining a healthy lifestyle:   your per... Metastatic liver cancer blogs http://www.medworm.com/rss/comments.php?id=1622242 Tue, 15 Jul 2008 09:05:11 +0100 1622242 http://www.medworm.com/index.php?rid=1454885&cid=t_105639_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F294196026%2F The well known major risk factors for developing bladder cancer are prolonged exposure to certain environmental pollutants and chemicals. As the body absorbs carcinogenic chemicals, such as cigarette smoke, the chemicals are transferred to the blood, filtered out by the kidneys and expelled from the body through the urine. Greater concentrations of chemicals in the urine can damage the endothelial lining of the bladder and increase a patient’s odds of developing transitional cell carcinoma (TCC). One group of people that are regularly exposed to smoke and chemical fumes are firefighters – more than any other group. Now, University of California –San Francisco reported at the Annual Scientific Meeting of the American Urological Association (AUA), research findings suggesting that... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=1454885 Tue, 20 May 2008 11:21:14 +0100 1454885 http://www.medworm.com/index.php?rid=1454242&cid=t_105639_115_f&fid=34670&url=http%3A%2F%2Fsumerdoc.blogspot.com%2F2008%2F05%2Fhepatocellular-carcinoma-with-inferior.html HCC is a malignant tumor of hepatocellular origin that develops in patients with risk factors such as alcohol abuse, viral hepatitis, and metabolic liver disease. It can also occur, rarely, in patients with normal liver parenchyma. Grossly, HCC can undergo hemorrhage and necrosis because of a lack of fibrous stroma. Vascular invasion, particularly of the portal system, is common. This is a known case of HCC with raised alphfetoprotein with MRI showing inferior vena cava and right atrial thrombus.Dr.Sumer K Sethi, MDConsultant Radiologist ,VIMHANS and CEO-Teleradiology Providers Editor-in-chief, The Internet Journal of Radiology Director, DAMS (Delhi Academy of Medical SciencesFrom Sumer's Radiology Site http://www.sumerdoc.blogspot.com -The Top Radiology Magazine (Source: Sumer's Radiology... Sumer's Radiology Site blogs http://www.medworm.com/rss/comments.php?id=1454242 Tue, 20 May 2008 05:27:00 +0100 1454242 http://www.medworm.com/index.php?rid=1426548&cid=t_105639_136_f&fid=35300&url=http%3A%2F%2Fwww.metastaticlivercancer.org%2F2008-05-07-cancer-treatment%2F2-responses-to-metastatic-liver-cancer%2F Sandra and Glen left a comment on our April Metastatic Liver Cancer post, which we will add below in italics and our feedback in normal script. Glen’s Liver Cancer story Thank you for sharing your story. My mom, aged 71, has been diagnosed as having HHC (Hepatocellular Carcinoma) in April 08. Her MRI indicated multiple Metastasis in her liver (innumerable large and small tumors). Sounds like father’s diagnosis: lots of words we heard for the first time and when we saw the picture of his liver it became all clear to us: innumerable small tumors scattered in his liver… Her blood tests indicated elevated Alpha Fetoprotein, and her history of chronic Hepatitis added to the diagnosis of liver tumor. The liver tumor involves both lobes (which makes it not curable by resection,... Metastatic liver cancer blogs http://www.medworm.com/rss/comments.php?id=1426548 Wed, 07 May 2008 10:19:42 +0100 1426548 http://www.medworm.com/index.php?rid=1294838&cid=t_105639_117_f&fid=36026&url=http%3A%2F%2Fblog.healthtalk.com%2Fzimney%2Fskin-cancer-what-we-can-learn-from-greys-anatomy-star-eric-mcsteamy-dane%2F Skin cancer is far and away the most common type of cancer. Fortunately, the cure rate is so high that it makes skin cancer distinctly different from nearly all other forms of cancer - so distinct, in fact, that when you hear about cancer statistics like the most common types of cancer, they are not even considering or including skin cancer. Typically, we hear that lung, breast, prostate and colon cancers are the most common types, but you should be aware that this means “excluding skin cancer.” There are three types of skin cancer, each named for the type of skin cell from which it originates. The two most common types are called squamous cell and basal cell carcinoma, and the third is melanoma. Squamous cell and basal cell carcinomas together are often called non-melanoma skin cancer... Dr. Z's Medical Report blogs http://www.medworm.com/rss/comments.php?id=1294838 Tue, 11 Mar 2008 19:42:35 +0100 1294838 http://www.medworm.com/index.php?rid=1176219&cid=t_105639_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F222582280%2F According to a study that appeared online in the January 22 issue of Lancet Oncology, patients taking Nexavar® (sorafenib) need to be carefully monitored and treated. In clinical testing, Nexavar improved overall survival by 44 percent among people with HCC. Median overall survival was 10.7 months among those treated with the drug, versus 7.9 months among those who took a placebo. This was considered a major inroad against one of the most voracious cancers. Nexavar is also being assessed to treat small-cell lung cancer, prostate cancer and melanoma.Earlier trials, however, had shown a 16 percent to 42.6 percent incidence of hypertension in patients taking the drug. If not properly controlled, hypertension can lead to strokes and heart attacks, as well as kidney failure. For this paper, re... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=1176219 Fri, 25 Jan 2008 00:00:41 +0100 1176219 http://www.medworm.com/index.php?rid=1141024&cid=t_105639_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F214242047%2F The Moffitt Cancer Center in Tampa, Florida is seeking patients who have primary liver cancer (hepatocellular carcinoma) that has spread to other organs or is too advanced to be treated by surgery and must have had prior chemotherapy treatments. The said patients are being recruited by Moffitt for the phase II study of the oral medication AZD6244 — an experimental anti-cancer drug that may stop the growth of cancer cells and is designed to block the pathway of a protein called MEK (important for cell survival). According to Dr. Chris R. Garrett, principal investigator with Moffitt’s Gastrointestinal Oncology program: “There’s no cure for advanced liver cancer that’s not amenable to surgery. We’re looking for a novel therapy to improve the outcome for patients with the disea... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=1141024 Thu, 10 Jan 2008 07:14:45 +0100 1141024 http://www.medworm.com/index.php?rid=809591&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F08%2F20%2Fthought-for-the-day-mri-as-a-gold-standard%2F Filed under: Breast Cancer, Prevention, Thought for the DayJust recently, European researchers announced that MRI scans offer a new way to detect breast cancer in its earliest form. They can even prevent cancer among high-risk women.Better than standard mammograms, MRI can detect a nonmalignant tumor called ductal carcinoma in-situ, or DCIS. Once found, the lesion can be surgically removed before it becomes cancerous.Think about this: It is believed that almost all breast cancer starts out as DCIS. And this: if MRI were the gold standard breast cancer screening tool, we might be able to prevent a lot more breast cancer cases than we do now. It seems researchers agree."MRI should thus no longer be regarded as an adjunct to mammography but as a distinct method to detect breast cancer at its ... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=809591 Mon, 20 Aug 2007 04:00:00 +0100 809591 http://www.medworm.com/index.php?rid=800060&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F08%2F15%2Fcancer-by-the-numbers-basal-cell-carcinoma%2F Filed under: Skin Cancer, Cancer by the NumbersMy sister has skin cancer -- the basal cell variety. She has two spots, both on her chest, each one scheduled to be surgically removed in a few weeks. If it were me with this new diagnosis, I'm sure I'd be freaking out, maybe because I've already had breast cancer and tend to panic about any cancer or maybe just because I'm a worrier by nature. But my sister is taking her cancer news in stride, and I am too -- because now that I've done a little research, it seems this type of cancer is pretty easy to beat.Here's a little refresher lesson on the skin: The skin is the largest organ in the body, and is made of three layers -- the epidermis (top layer), dermis (middle layer), and subcutis (deepest layer). For the purpose of this post, let's focus... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=800060 Wed, 15 Aug 2007 04:00:00 +0100 800060 http://www.medworm.com/index.php?rid=794147&cid=t_105639_115_f&fid=34670&url=http%3A%2F%2Fsumerdoc.blogspot.com%2F2007%2F08%2Fhepatocellular-carcinoma-mri-findings.html Notes for residents---A patient of alcoholic disease with raised alfa foetoprotein (can be more than 1000 ng/ml in 50% cases) and FNAC postive HCC. Features include capsule formation, presence of fat, suppressed on out of phase GRE images, no definite portal venous or hepatic venous invasion, No MR demonstrable calcification or biliary dilatation.Color doppler showed plenty of vascularity with increased diastolic flow.More common in males (7 to 8 times) more in 30-60 yrs. Contrast study would show increased early arterial enhancement, No significant contrast on equilibrium stage or hepatobiliary phase (1 hour) because hepatocytes are unable to excrete gadolinium in to bile and show it. Another feature would be peripheral washout in portal venous pahse. Pseudocapsule can enhance in portal v... Sumer's Radiology Site blogs http://www.medworm.com/rss/comments.php?id=794147 Sun, 12 Aug 2007 14:45:00 +0100 794147 http://www.medworm.com/index.php?rid=745509&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F07%2F20%2Fsurvival-spotlight-cancer-again%2F Filed under: Breast Cancer, Skin Cancer, Survivor SpotlightI did a post back in August of last year about my friend Larissa's journey through breast cancer. Larissa was just recently diagnosed with cancer again. This time it was skin cancer, basal cell carcinoma. I asked Larissa if she would talk about her experience and how it felt to be diagnosed with cancer yet again. Larissa blogs at Welcome to the Dallehouse. How did you find out you had skin cancer? I had a red patch on my face that didn't go away for several months. I kept an eye on it and noticed it was getting larger so I made an appointment with a dermatologist. The dermatologist thought it looked suspicious and did a shave biopsy. The biopsy came back positive for basal cell carcinoma. What types treatments were recommended? MO... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=745509 Fri, 20 Jul 2007 04:00:00 +0100 745509 http://www.medworm.com/index.php?rid=699265&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F06%2F27%2Fkidney-cancer-makes-david-foster-sick%2F Filed under: Kidney Cancer, BlogsDavid Foster was diagnosed with Advanced Renal Cell Carcinoma in April 2005. Translation: stage four kidney cancer and the sixth deadliest form of cancer. Not a great disease to acquire. Also not the end of the world. Just ask David who is busy working as a National Strategic Advisor in Augusta, Georgia, headlining within the independent magazine community, hanging out with dog Gracie, and documenting his journey in a blog he calls David Foster's Kicking Kidney Cancer's Arse.He's no wimp, this guy. Just read his June 23 post, titled May kill me, but it ain't gonna beat me. He didn't let that hard-nosed kid Jerry whip him when he was eight -- he smacked him so hard in the lunchroom, Jerry was left stumbling and bleeding -- and he won't let cancer bully him e... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=699265 Wed, 27 Jun 2007 04:00:00 +0100 699265 http://www.medworm.com/index.php?rid=650892&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F06%2F01%2Finterferon-may-improve-survival-in-advanced-liver-cancer%2F Filed under: Drug, Liver Cancer, Research, SurgeryInterferon is an immune stimulating agent. According to an article recently published in the Annals of Surgery, administration of interferon following surgery may improve survival among patients with advanced hepatitis B-related hepatocelluar carcinoma. Hepatocelluar carcinoma (HCC) is the most common type of liver cancer. Unfortunately for this disease, recurrences often happen after surgical removal of the cancer. Researchers continue to evaluate ways to reduce these recurrences. A clinical trial was conducted to evaluate the use of interferon following surgery in patients with HCC. The trial included 80 patients, one group received the interferon after surgery and the other group received no further treatment. The researchers found that ... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=650892 Fri, 01 Jun 2007 04:00:00 +0100 650892 http://www.medworm.com/index.php?rid=612004&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F05%2F16%2F3d-model-of-breast-cancer-created-in-test-tube%2F Filed under: Breast Cancer, Research, Daily newsUK researchers have developed a 3D laboratory model of human breast cancer, specifically ductal carcinoma in situ (DCIS). The model, complete with normal cells and tumor cells, should help experts understand how the disease develops in its early stages, and it could replace the need for experiments in animals.About one in five breast cancers in the UK start out as DCIS. Researchers wanted to learn more about how the early cancerous changes in cells develop into larger tumors, and they chose to fashion a 3D test tube model because it is more complex than a layer of cells in a Petri dish.Once this experiment is proved successful, it could reduce and perhaps replace animal studies."With breast cancer, there is an urgent need to move away from an... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=612004 Wed, 16 May 2007 04:00:00 +0100 612004 http://www.medworm.com/index.php?rid=601859&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F05%2F11%2Ftea-time-can-lower-your-risk-of-skin-cancer%2F Filed under: Skin Cancer, PreventionThose who drink one or two cups of tea daily may have a lower risk of developing two types of skin cancer by 20 to 30 percent. In a study conducted on nearly 2,200 adults, researchers found that tea drinkers had a lower risk of developing squamous cell and basal cell carcinoma, the two most common forms of skin cancer. The findings were published in the Journal of the American Academy of Dermatology. Tea drinking did not show any effect on the worst skin cancer, melanoma. Still, the findings support the theory that tea antioxidants may limit the damage UV radiation inflicts on the skin, according to the study authors, led by Dr. Judy R. Rees of Dartmouth Medical School in Lebanon, New Hampshire. The researchers do warn that it is not okay to bake in the... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=601859 Fri, 11 May 2007 04:00:00 +0100 601859 http://www.medworm.com/index.php?rid=566334&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F04%2F24%2Fblack-raspberries-slowing-growth-of-skin-cancer%2F Filed under: Skin Cancer, Prevention, Non-toxic alternatives, Cancer prevention foodsUVB radiation is thought to be the most dangerous light in the solar spectrum. Scientists think that UVB light causes most of the non-melanoma skin cancers. When you're exposed to UVB radiation for a period of time, it inflames the skin and causes sunburn. Squamous cell carcinoma is diagnosed in about 250,000 people each year in the United States. The cancer can arise from the inflammation of the skin by possible DNA damage. Even though the scientist's discovery was only so far seen in mice, the researchers at the Ohio State University Medical Center say that a topical compound made of black raspberries significantly slows the growth of Squamous cell skin cancer. The scientists think that the cancer fighti... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=566334 Tue, 24 Apr 2007 04:00:00 +0100 566334 http://www.medworm.com/index.php?rid=530928&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F04%2F09%2Fcollege-basketball-grad-coby-karl-resting-up-for-nba%2F Filed under: Thyroid Cancer, Daily news, Cancer Survivors, SportsIt's been a rough road for former Boise State basketball player Coby Karl, son of Denver Nuggets coach George Karl. The younger Karl, 23, had his thyroid removed 13 months ago due to papillary carcinoma, a treatable form of cancer. And he returned to the operating room just last week for the removal of cancerous lymph nodes.Karl's recent surgery, intended to take two to three hours, lasted for seven hours. This worried Dad. ''When it goes longer and longer, you always think the worst, and start worrying about things like being under anesthesia that long and all the nightmares you have about surgeries,'' George Karl said. But it turns out Coby was just fine -- doctors just wanted to be thorough -- and the ambitious young man p... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=530928 Mon, 09 Apr 2007 04:00:00 +0100 530928 http://www.medworm.com/index.php?rid=522844&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F04%2F05%2Fnuggets-coach-misses-lakers-game-cares-for-son%2F Filed under: Prostate Cancer, Thyroid Cancer, Daily news, SportsDenver Nuggets coach George Karl missed his team's match-up against the Lakers Tuesday night so he could spend some quality time with his son, Coby, who had surgery for the removal of cancerous lymph nodes on Monday.Coby Karl, 23, spent seven hours in surgery. It was his second surgery in 13 months -- he had his thyroid removed last year after he was diagnosed with a treatable form of cancer called papillary carcinoma. Chemotherapy followed the first surgery to kill off any remaining cancer cells.All reports indicate both Karls are doing fine and Coach Karl, who has been surviving prostate cancer since 2005, was back to his coaching duties last night. His team took on the Sacramento Kings -- and won. Coby Karl is taking it eas... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=522844 Thu, 05 Apr 2007 04:00:00 +0100 522844 http://www.medworm.com/index.php?rid=489979&cid=t_105639_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F03%2F21%2Fson-of-denver-nuggets-coach-battles-cancer%2F Filed under: Thyroid Cancer, Daily news, Sports, SurgeryBoise State basketball player Coby Karl, son of Denver Nuggets coach George Karl, had surgery 13 months ago to remove his thyroid after he was diagnosed with papillary carcinoma, a form of treatable cancer. And while Karl received chemotherapy to kill off any lingering cancer cells, he must undergo cancer surgery once again.Karl, who plans to play in the NABC All-Star game in Atlanta on March 31, will return to Boise on April 2 for surgery to remove cancerous lymph nodes.The lymph node cancer was identified in January, but Karl, 23, kept his condition private until his team lost to New Mexico State in the Western Athletic Conference tournament semifinals. This ended the Broncos' season. And now begins Karl's second go-round with cance... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=489979 Wed, 21 Mar 2007 04:00:00 +0100 489979