MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'carpenter'. Sat, 03 Sep 2011 02:32:20 +0100 http://www.medworm.com/index.php?rid=4984687&cid=t_295903_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2F8Pxx2sLGKGM%2F After months of controversy, an FDA advisory panel yesterday voted unanimously to uphold an earlier agency decision to yank the breast cancer indication for Avastin, a widely used sold by Roche and its Genentech unit (see this). The run-up to the two-day meeting was highly contentious as the drugmaker accused the FDA panel of bias, there were behind-the-scenes debates over potential conflicts of interest among expert speakers, and patients and their families organized protests - online and in person. Clearly, more was at stake than the fate of a best-selling med, which remains available for treating other cancers. The hearing was also a referendum of sorts on the veracity of the FDA accelerated approval program and, by extension, the agency itself. We asked Daniel Carpenter, the Allie S. F... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4984687 Thu, 30 Jun 2011 12:45:07 +0100 4984687 http://www.medworm.com/index.php?rid=3746986&cid=t_295903_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2F-CbIiY0mVwQ%2F This report could change the Avandia game entirely. For one, if Marciniak’s view is widely held at the FDA (or it’s widely shared among its advisory committee), then we no longer have a case in which the clinical trials point one way and the observational evidence points the other way. More important, because Marciniak is a CDER reviewer, we no longer have a case in which the FDA’s ‘trialists’ are entirely at odds with its ‘observationalists.’ In other words, Marciniak’s memo may create doubt among many CDER medical reviewers who favor randomized clinical trials but who may come to doubt GSK’s credibility in running them. That kind of loss of trust can be severely destructive for a company. As far as I can tell, Marciniak’s voice is a new one in this debate, and combine... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3746986 Mon, 12 Jul 2010 13:09:05 +0100 3746986 http://www.medworm.com/index.php?rid=2611140&cid=t_295903_135_f&fid=35274&url=http%3A%2F%2Facidrefluxweb.com%2F%3Fp%3D3820 About a month ago, during the height of my Lithium/France Farmer withdrawal state of mind, I took out my dogs to Allen Gardens off leash area. Though never at the butcher, but more of a crack house large dog side, but where all the little princess, mob dogs, and people who don’t realize a puppy who will grow up to be a 100 pounds at nine weeks does not mix with very wee adult dogs. I began my ritual off equipping myself with the iPod headphones in , and dark sunglasses on. This equipment is necessary to escape the Mylie Cyrus-like adoration the little 2.5-pound Chihuahua gets while out and about. The sun was out, I was into my music, and then suddenly while trying to get into my apartment a friend of mine was opening the door for me, and another woman outside was just staring at me. ... acidrefluxweb.com blogs http://www.medworm.com/rss/comments.php?id=2611140 Thu, 16 Jul 2009 17:18:26 +0100 2611140 http://www.medworm.com/index.php?rid=2786022&cid=t_295903_109_f&fid=38951&url=http%3A%2F%2Fcarlatpsychiatry.blogspot.com%2F2009%2F07%2Fold-friends-battle-it-out-over-dsm-v.html Yesterday, Psychiatric Times published this response to the Allen Frances critique of DSM-V. It is written by William Carpenter, who is Professor of Psychiatry at the University of Maryland, and the chairman of the DSM-V work group on psychosis.Carpenter begins his response by saying that Allen Frances is an "old friend," although from the tenor of this article, "old" may be the operative word. I know Dr. Carpenter myself, having interviewed him for the March 2007 issue of The Carlat Psychiatry Report, and having chatted with him here and there at APA meetings. He's a southern gentleman, and I found him very forthcoming and honest about a range of issues, including his refreshing skepticism of the value of some of the newer atypical antipsychotics. He has done some consultation with drug c... The Carlat Psychiatry Blog blogs http://www.medworm.com/rss/comments.php?id=2786022 Wed, 08 Jul 2009 14:47:00 +0100 2786022 http://www.medworm.com/index.php?rid=2142578&cid=t_295903_136_f&fid=37852&url=http%3A%2F%2Fdonnatrussell.com%2F2009%2F01%2F28%2Ftwelve-tips-for-the-cancer-patient%2F 1) You are sick. You have an incurable disease. You are in the fight of your life. All the happy images of cancer you’ve seen on TV? Forget them. 2) You will be tired. You will be sad. You will be irritable. You will feel guilty for being a lousy parent/friend/coworker. 3) You will feel lazy and unfocused. You will find that your old interests now seem like chores. 4) You will hear lots and lots of advice on how to beat cancer. Unless that advice is coming from an oncologist, ignore it. 5) You will make people nervous. You will lose some friends. You will miss them. 6) You will miss yourself. You will miss the life you had before cancer. 7) You will make new friends. You may not love them the way you loved your old friends. You may not even like them very much. But you will find comf... Donna Trussell blogs http://www.medworm.com/rss/comments.php?id=2142578 Thu, 29 Jan 2009 20:12:08 +0100 2142578 http://www.medworm.com/index.php?rid=2138987&cid=t_295903_136_f&fid=37852&url=http%3A%2F%2Fdonnatrussell.com%2F2009%2F01%2F28%2Ftwelve-tips-for-the-cancer-patient%2F 1) You are sick. You have an incurable disease. You are in the fight of your life. All the happy images of cancer you’ve seen on TV? Forget them. 2) You will be tired. You will be sad. You will be irritable. You will feel guilty for being a lousy parent/friend/coworker. 3) You will be lazy and unfocused. You will find that your old interests now seem like chores. 4) You will hear lots and lots of advice on how to beat cancer. Unless that advice is coming from an oncologist, ignore it. 5) You will make people nervous. You will lose some friends. You will miss them. 6) You will miss yourself. You will miss the life you had before cancer. 7) You will gain new friends. You may not love them the way you loved your old friends. You may not even like them very much. But you will find comfor... Donna Trussell blogs http://www.medworm.com/rss/comments.php?id=2138987 Wed, 28 Jan 2009 15:29:37 +0100 2138987 http://www.medworm.com/index.php?rid=1868734&cid=t_295903_109_f&fid=36089&url=http%3A%2F%2Fthesituationist.wordpress.com%2F2008%2F10%2F11%2Fthe-situation-of-punishment-and-forgiveness%2F Benedict Carey had an interesting piece last week in the New York Times, titled “Citizen Enforcers Take Aim.”  Here are some excerpts. * * * The public urge for punishment that helped delay the passage of Washington’s economic rescue plan is more than a simple case of Wall Street loathing, according to scientists who study the psychology of forgiveness and retaliation. The fury is based in instincts that have had a protective and often stabilizing effect on communities throughout human history. Small, integrated groups in particular often contain members who will stand up and — often at significant risk to themselves — punish cheaters, liars and freeloaders. Scientists debate how common these citizen enforcers are, and whether an urge to punish infractions amounts to an... The Situationist blogs http://www.medworm.com/rss/comments.php?id=1868734 Sat, 11 Oct 2008 11:03:18 +0100 1868734 http://www.medworm.com/index.php?rid=1575644&cid=t_295903_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F325735091%2F A Harvard University professor defended research suggesting the FDA was too hasty in approving drug, which the agency has criticized as mistaken, The Wall Street Journal writes. The professor, Daniel Carpenter, acknowledged that the FDA had identified mistakes in his study, which was published by the New England Journal of Medicine in March. But he said that the FDA’s own records also had errors, and that after he made necessary corrections, his original finding still held: Drugs the FDA has approved soon before a regulatory deadline have been more likely to develop severe safety problems later on, the paper continues. Between 1993 and 2005, the 88 drugs approved near the FDA’s deadline had a 15 percent chance of being flagged for severe safety problems, either a Black Box warn... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1575644 Thu, 03 Jul 2008 11:57:03 +0100 1575644