MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'cas'. Sat, 03 Sep 2011 02:31:58 +0100 http://www.medworm.com/index.php?rid=4512478&cid=t_172908_115_f&fid=38592&url=http%3A%2F%2Fwww.radiolopolis.com%2Findex.php%2Fmy-profile%2Fmy-blog%2Finteractive-stack-viewer-for-radiology-cases-tutorial.html How to use the interactive stack viewer1-Toolbar:The toolbar is available at the bottom of the viewer It offers many features:1.    Full Mode: toggle screen normal/full mode2.    High Quality Button: load HQ version of the current shown Image.3.    Pan Button: when selected Read More... (Source: Radiolopolis Blogs) Radiolopolis Blogs blogs http://www.medworm.com/rss/comments.php?id=4512478 Wed, 23 Feb 2011 20:11:26 +0100 4512478 http://www.medworm.com/index.php?rid=2785966&cid=t_172908_107_f&fid=36698&url=http%3A%2F%2Fminingdrugs.blogspot.com%2F2009%2F09%2F50-million-chemicals-and-accelerating.html (via NatureNews) As reported by the Chemical Abstract Service (CAS) have they reached 50 million registered chemical entities.Here some numbers to think aboutCAS needed 33 years for registering the first 10 million compounds, that is one new compound every 101.5 seconds.the last 9 months CAS registered 10 million compounds, in other words, every 2.3 seconds a new compound was created !So, chemistry has improved its efficiency 44 times !This resulted in a drastically increasing patenting rate as mentioned by David Bradley. O.k. what happens now to your actual lead structure series? Don't panic! Just get enough money for mining CAS directly ... mmmh ... just kidding.Second choice? Extract all 50 million structures from PDF patents, which is really difficult and noisy, I mean it.Third choice?... Mining Drug Space blogs http://www.medworm.com/rss/comments.php?id=2785966 Thu, 10 Sep 2009 19:07:00 +0100 2785966 http://www.medworm.com/index.php?rid=2772554&cid=t_172908_107_f&fid=36672&url=http%3A%2F%2Fwww.sciencebase.com%2Fscience-blog%2F50-million-chemicals.html Chemical Abstracts Service (CAS) will announce the 50 millionth registered chemical substance in its Registry, tomorrow (8th September). According to the email I received from a CAS spokesman, “The number itself represents an important milestone both for researchers and CAS, but even more significant is the pace of scientific discovery around the world.” Roger Schenck, Manager of the Content Planning Department at CAS, adds that, “More scientific literature is being published and we have noticed an explosive growth of patent literature since 1998 that accounts for the rapid growth of substance information available.” By contrast, it took 33 years for CAS to register 10 million compounds, a milestone reached in 1990. It’s intriguing to think that two decades af... Sciencebase Science Blog blogs http://www.medworm.com/rss/comments.php?id=2772554 Mon, 07 Sep 2009 12:00:48 +0100 2772554 http://www.medworm.com/index.php?rid=2424171&cid=t_172908_107_f&fid=36698&url=http%3A%2F%2Fminingdrugs.blogspot.com%2F2009%2F05%2Fpeer-recognition-and-building.html "Experts will want to contribute to coworkers who need them, who will hear them, who will respect them and who may even thank them. ... Rather than asking, How do we incentivise people to share their knowledge? It would be more useful to ask, How do we develop relationships across the globe that will set in motion more knowledge sharing?" [slightly generalized after Nancy Dixon]"Today there seems to be a new distribution model that is emerging. One that is based on people’s ability to publically syndicate and distribute messages — aka content — in an open manner. This has been a part of the internet since day one — yet now its emerging in a different form — it's not pages, it's streams, its social and so its syndication." [John Borthwick]Recently, there are many efforts ongoing... Mining Drug Space blogs http://www.medworm.com/rss/comments.php?id=2424171 Tue, 19 May 2009 19:16:00 +0100 2424171 http://www.medworm.com/index.php?rid=2017621&cid=t_172908_132_f&fid=35014&url=http%3A%2F%2Fharijay.wordpress.com%2F2008%2F12%2F05%2Fa-naive-biochemist-wakes-up-to-the-closed-world-of-chemical-abstracts-and-such%2F We have a project in the lab that involves screening small molecule inhibitors that inhibit the transport activity of a membrane protein on a “lab scale”  . Having identified one such inhibitor we intended to look for similar molecules that share the same substructure . Substructure query is a standard procedure in chemical informatics . In the past I have screencast the use of the Sigma-Aldrich service to identify molecules from sigmas catalog based on similarity .  However  considering the wealth of biochemically relevant  information PUBCHEM offers , I was curious to try out the substructure query at PUBCHEM .  This Pubchem service works great and is very feature rich ( screencast coming soon) and gave me several molecules which could be of interest in my screen. T... The Omics world blogs http://www.medworm.com/rss/comments.php?id=2017621 Fri, 05 Dec 2008 16:18:55 +0100 2017621 http://www.medworm.com/index.php?rid=1980527&cid=t_172908_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F11%2F21%2Fthis-week%25e2%2580%2599s-journal-arrivals-at-the-fade-library%2F BMJ 2008 (Vol 337, No 7680) Contents Page Fade Fave Article: Effect of social deprivation on blood pressure monitoring and control in England: a survey of data from the quality and outcomes framework Fade Skinny: Implementation of performance indicators in primary care and pay for performance in 2004, blood pressure monitoring and control have improved substantially. Improvements in achievement have been accompanied by the near disappearance of the achievement gap between least and most deprived areas. (Online access with NHS Athens password) Education for Primary Care (Vol 19 No 6) Contents Page Fade Fave Article: The current state and value of deanery-managed continuing professional development in primary care: the general practice appraisers’ perspective Fade Skinny: Identifies that ... Fade Library blogs http://www.medworm.com/rss/comments.php?id=1980527 Fri, 21 Nov 2008 10:10:21 +0100 1980527 http://www.medworm.com/index.php?rid=1288690&cid=t_172908_107_f&fid=36698&url=http%3A%2F%2Fminingdrugs.blogspot.com%2F2008%2F03%2Fcas-numbers-are-not-public-domain-are.html "Work created before the existence of copyright and patent laws also form part of the public domain. The Bible and the inventions of Archimedes are in the public domain. However, copyright may exist in translations or new formulations of this work." [Wikipedia]As posted by Tony is the Chemical Abstract Service (CAS) discouraging using their CAS services for assigning correct CAS numbers to structures for any third party database. Wikipedia is a source of structures, which is public domain due to its GNU FDL. Still, this does not imply that any translation of structures, e.g. CAS numbers, are in the public domain, too. Honestly, this raises a serious problem for curating CAS numbers on Wikipedia and this raises indeed the question, if they should not be dropped from Wikipedia, and any other... Mining Drug Space blogs http://www.medworm.com/rss/comments.php?id=1288690 Sat, 08 Mar 2008 09:00:00 +0100 1288690