MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'cell cycle'. Sat, 03 Sep 2011 02:51:49 +0100 http://www.medworm.com/index.php?rid=3362486&cid=t_163806_122_f&fid=35068&url=http%3A%2F%2Fwww.molecularbrain.com%2Fcontent%2Fdownload%2Fsupplementary%2F1756-6606-3-5-s3.mov Atsushi Miyawaki’s lab has developed a series of neat tools for visualizing cell cycle progress. For zebrafish, the zFucci system consists of two fluorescent proteins, mKO2 and mAG, that are fused to Cdt1 and geminin genes.  Cell cycle- regulated proteolysis of these fusion proteins causes each cell to display orange fluorescence in G1 phase nuclei and green fluorescence in both the nucleus and cytoplasm of S/G2/M phase cells. Video of cell cycle transitions in culture. Click for the video. The last time I saw Atsushi give a talk, he showed an incredible time lapse video from the zebrafish cleavage stage that I haven’t been able to find online.  However, here is a video from later in development of the zebrafish that is still pretty remarkable. Development of a zebrafish visu... Brain Windows blogs http://www.medworm.com/rss/comments.php?id=3362486 Sat, 13 Mar 2010 16:08:39 +0100 3362486 http://www.medworm.com/index.php?rid=1816188&cid=t_163806_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F399892651%2F This article was published on Highlight HEALTH. Other Articles You May LikeNovel Gene Suppresses Tumor Growth in Multiple CancersTumor Suppressors and OncogenesThe Promise of Stem Cells to Repair the HeartMapping Connections in the Human BrainIncreased Coffee Consumption Associated with Lower Risk of Liver Cancer (Source: Highlight HEALTH) Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1816188 Mon, 22 Sep 2008 21:46:49 +0100 1816188 http://www.medworm.com/index.php?rid=1354188&cid=t_163806_132_f&fid=35624&url=http%3A%2F%2Fsuicyte.wordpress.com%2F2008%2F04%2F06%2Frandom-stuff-april-08%2F Here are just two interesting stories I read on other peoples blogs: First, Jake Young at Pure Pedantry blogs about a recent Cell paper by Sakaue-Sawano et al. who present a clever application of protein ubiquitination for visualizing the cell cycle stage of cells in vivo. Lars Juhl Jensen at Buried Treasure has also picked up this story, and those two blogs provide a lot of detail on the method, including a link to a nice video showing HeLa cells passing through 3 cell cycles. In brief, the authors of this paper exploit the fact that several protein ubiquitination systems are only active during particular phases of the cell cycle. On one hand, there is the APC/Cyclosome system, which degrades target proteins only in late mitosis (APC means Anaphase Promoting Complex) and in G1 phase. Conv... Suicyte Notes blogs http://www.medworm.com/rss/comments.php?id=1354188 Sun, 06 Apr 2008 22:32:01 +0100 1354188 http://www.medworm.com/index.php?rid=554442&cid=t_163806_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F04%2F19%2Fmarijuana-halts-lung-cancer-growth-by-half%2F Filed under: Drug, Lung Cancer, Research, Daily newsMore and more media reports are mentioning the potential merits of marijuana. The most recent headlines say the active ingredient in the drug cuts tumor growth in common lung cancers in half and greatly reduces the ability of the cancer to spread.Researchers at Harvard University tested marijuana's main ingredient, delta-tetrahydrocannabinol or THC, in both lab and mouse studies and say their experiments are the first to show THC inhibits the growth of cancer.Researchers are not certain why THC inhibits tumor growth, but it could be that the substance activates molecules that arrest the cell cycle. THC may also interfere with angiogenesis and vascularization, which promotes cancer growth.There is a long way to go in the study of THC. Yet ... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=554442 Thu, 19 Apr 2007 04:00:00 +0100 554442