MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'chromatin'. Sat, 03 Sep 2011 02:28:24 +0100 http://www.medworm.com/index.php?rid=3519621&cid=t_104593_131_f&fid=35005&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Ffungalcompgenomics%2F%7E3%2F8T_DqOMWXGw%2F Check out Zach Lewis’s Chromatin Chronicles for all good things about chromatin biology and epigenetics. (Source: Fungal Genomes and Comparative Genomics) Fungal Genomes and Comparative Genomics blogs http://www.medworm.com/rss/comments.php?id=3519621 Fri, 30 Apr 2010 16:03:35 +0100 3519621 http://www.medworm.com/index.php?rid=2832338&cid=t_104593_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F9r0qn2IL2dM%2F For many of us, GENETICS is a intimidating topic. Don’t worry, I feel the same way around technology and computer language. When we start reading sentences where half the words are foreign, then it can seem way over our heads. And I think people have an idea that genetics is important to medicine and health care, but what role it plays (and how genes act) might be where the questions are. So that’s why I’m adding a regular feature to explain the basics and call it “What we need to know to get genetics” or something like that. Obviously, this won’t be the “complete course in Genetics 101” or “Genetics for Dummies” (there’s a already a Genetics For Dummies (For Dummies (Math & Science))’ target=_blank>book on that) but hopefully the outlines below would be... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2832338 Fri, 25 Sep 2009 04:39:47 +0100 2832338 http://www.medworm.com/index.php?rid=2026813&cid=t_104593_132_f&fid=35016&url=http%3A%2F%2Fpeanutbutter.wordpress.com%2F2008%2F12%2F09%2Fmelting-away-misconceptions-the-strucure-of-the-mitotic-chromosome%2F I am sure many of you remember sitting in a science class as a child, or an early undergraduate course, being taught about cell replication. How DNA is passed from one cell to the next via either mitosis or meiosis in order to effect DNA replication and gene expression, so that the genetic information content of the DNA can be passed from one generation to the next. DNA can be organised inside packages within cells. These packages are called chromatin, which are found inside the nuclei of eukaryotic cells and the nucleoid of prokaryotic cells. Chromatin [1] is a complex combination of DNA, RNA and protein that forms a chromosome. To date, the commonly accepted hypothesis is that chromatin can take the following three organisational forms DNA wrapping around nucleosomes - The “be... peanutbutter blogs http://www.medworm.com/rss/comments.php?id=2026813 Wed, 10 Dec 2008 11:39:25 +0100 2026813 http://www.medworm.com/index.php?rid=2011145&cid=t_104593_131_f&fid=34990&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fepigeneticsnews%2F%7E3%2F458418742%2F While Landes Bioscience made headway by debuting a journal devoted solely to epigenetics (Epigenetics), BMC has really opened the door to epigenetics research by debuting the first open-access journal devoted to epigenetics. Epigenetics & Chromatin is a new open-access option for researchers wanting to make their research available to a wider audience. The co-editors, Steven Henikoff and Frank Grosveld, are open to a wide range of topic areas: Epigenetics & Chromatin will publish articles aimed at understanding how gene and chromosomal elements are regulated and their activities maintained during cell division, self-renewal, differentiation and environmental alteration. Epigenetic research encompasses studies that use model systems to discover and investigate epigenetic mechanisms,... Epigenetics News blogs http://www.medworm.com/rss/comments.php?id=2011145 Wed, 19 Nov 2008 14:02:36 +0100 2011145 http://www.medworm.com/index.php?rid=1727806&cid=t_104593_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2008%2F07%2F23%2Ffrom-zero-to-hero-hmgb1-protein-found-to-promote-dna-repair-prevents-cancer%2F “An abundant chromosomal protein [HMGB1] that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of the National Academies of Science.” “An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=1727806 Wed, 23 Jul 2008 20:42:04 +0100 1727806 http://www.medworm.com/index.php?rid=557060&cid=t_104593_131_f&fid=34990&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fepigeneticsnews%2F%7E3%2F110697865%2F A new paper available today in PLoS Genetics suggests that a mammal-specific protein (DMRT7) related to the invertebrate sexual regulators Doublesex and MAB-3 controls the transition from meiotic sex chromosome inactivation to postmeiotic sex chromatin in males (1). Genes related to the sexual regulator Doublesex of Drosophila have been found to control sexual development in a wide variety of animals, ranging from roundworms to mammals. In this paper, we investigate the function of the Dmrt7 gene, one of seven related genes in the mouse. Female mammals are XX and males are XY, a chromosomal difference that presents specific challenges during the meiotic phase of male germ cell development. Some of these are thought to be overcome by incorporating the X and Y chromo- somes into a specialize... Epigenetics News blogs http://www.medworm.com/rss/comments.php?id=557060 Fri, 20 Apr 2007 20:40:49 +0100 557060 http://www.medworm.com/index.php?rid=485891&cid=t_104593_131_f&fid=34990&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fepigeneticsnews%2F%7E3%2F99479414%2F Nature has published a letter from researchers at the German Cancer Research Center involving their implication of the gene Gadd45a in one of the black boxes of epigenetic mechanisms: demethylation. DNA methylation is an epigenetic modification that is essential for gene silencing and genome stability in many organisms. Although methyltransferases that promote DNA methylation are well characterized, the molecular mechanism underlying active DNA demethylation is poorly understood and controversial. Here we show that Gadd45a (growth arrest and DNA-damage-inducible protein 45 alpha), a nuclear protein involved in maintenance of genomic stability, DNA repair and suppression of cell growth, has a key role in active DNA demethylation. Gadd45a overexpression activates methylation-silenced reporte... Epigenetics News blogs http://www.medworm.com/rss/comments.php?id=485891 Mon, 05 Mar 2007 14:54:20 +0100 485891