MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'clinical studies'. Sat, 03 Sep 2011 02:26:59 +0100 http://www.medworm.com/index.php?rid=4862926&cid=t_90012_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2Fq283udIKjWI%2F In another effort to shed light on untoward relationships, the FDA has just issued a draft guidance on financial conflicts of interest for clinical investigators and the drugmakers that enlist their assistance. The document is designed to revise a 10-year set of rules and address an issue that has grown increasingly contentious in recent years. “During the intervening years, interest has grown in the public disclosure of industry financial arrangements with physicians,” the agency writes. The “FDA is striving to achieve a proper balance between transparency and the right to privacy of clinical investigators with respect to their financial arrangements as expressed in the agency’s protection of privacy regulation.” The guidance would require any drugmaker to submit... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4862926 Tue, 24 May 2011 15:43:46 +0100 4862926 http://www.medworm.com/index.php?rid=4600795&cid=t_90012_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FfXx2YtVF-qo%2F More clinical trials may be run overseas, but work has not dried up in the US. In fact, a robust Phase I industry continues, but there are concerns since many volunteers supplement their incomes by enrolling in trials as often as possible. Consequently, sponsors and investigators worry data will be skewed by people who enroll too soon after participating in other trials. Patient advocates, meanwhile, worry about the risks participants may face from exposure to some meds and follow-up care. And so once again, the notion of a national Phase I clinical trial registry is being raised. The latest call for action comes from a pair of physicians who published a commentary piece this week in the Journal of the American Medical Association. In their view, a registry is long overdue in the US in ord... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4600795 Wed, 16 Mar 2011 15:01:29 +0100 4600795 http://www.medworm.com/index.php?rid=4277834&cid=t_90012_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Favastin-the-fdas-disappointing-decision%2F2010.12.21 “With this disappointing decision, the FDA has chosen to place itself between patients and their doctors by rationing access to a life-extending drug. . . We can’t allow this government takeover of health care to continue any longer.” That quote, courtesy of this morning’s [Dec 17th] Washington Post, incensed me to such a degree that I am writing this blog despite the two deadlines I have today. The speaker is Sen. David Vitter (R-La). The “disappointing decision” he refers to: The FDA’s decision to remove the breast cancer indication for Avastin (bevacizumab). I wrote about this earlier, and you can read the post here, but that was before yesterday’s [Dec 16th] decision. I’m not going to comment here on the benefits or risks of Avasti... Better Health blogs http://www.medworm.com/rss/comments.php?id=4277834 Tue, 21 Dec 2010 16:00:00 +0100 4277834 http://www.medworm.com/index.php?rid=4230157&cid=t_90012_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fpatient-centered-outcomes-research-will-patients-be-involved%2F2010.12.05 A year ago Gangadhar Sulkunte shared his story here about how he and his wife became e-patients of necessity, and succeeded, resolving a significant issue through empowered, engaged research. As today’s guest post shows, he’s now actively engaged in thinking about healthcare at the level of national policy, as well – and he calls for all patients to speak up about this new issue. – Dave I recently came across a Pauline Chen piece in the New York Times, “Listening to Patients Living With Illness.” It refers to a paper by Dr. Wu et al, ”Adding The Patient Perspective To Comparative Effectiveness Research.” According to the paper and the NY Times article, Dr. Wu and his co-authors propose: Making patient-reported outcomes a more routine part of clinical studi... Better Health blogs http://www.medworm.com/rss/comments.php?id=4230157 Sun, 05 Dec 2010 19:00:34 +0100 4230157 http://www.medworm.com/index.php?rid=1216588&cid=t_90012_117_f&fid=36026&url=http%3A%2F%2Fblog.healthtalk.com%2Fzimney%2Fhawthorne-for-heart-failure-good-news-and-bad-news%2F If you are an advocate of using natural remedies and you suffer from chronic heart failure, there’s good news on the beneficial effects of the herbal extract hawthorn. A recent analysis of 14 double-blind, randomized, placebo-controlled clinical studies (the best types of medical studies available) found that oral preparations using hawthorn leaf and flower extracts improved both symptoms and heart function in patients with chronic heart failure. But before you rush off to the pharmacy or use the Internet to order hawthorn products, please bear in mind the following facts: • Chronic heart failure is an extremely serious medical condition that requires careful diagnosis, ongoing monitoring and complex medical therapy • Most of the people in the 14 medical studies were receiving hawtho... Dr. Z's Medical Report blogs http://www.medworm.com/rss/comments.php?id=1216588 Thu, 07 Feb 2008 22:09:39 +0100 1216588 http://www.medworm.com/index.php?rid=677007&cid=t_90012_86_f&fid=35599&url=http%3A%2F%2Fshrlibrary.blogspot.com%2F2007%2F06%2Ffun-in-sun-update.html Since our first posting on Vitamin D and its Cancer fighting powers from May 24th the Canadian Cancer Society has announced its recommendations to increase the daily dosage of the sunshine medicine. The society now suggests that Canadians should be taking 1,000 international units of Vitamin D daily during fall and winter when sunshine is not all that powerful here in the Great White North. Subsequently, the CBC website has reported that since the Canadian Cancer Society has released its recommendation the sales of Vitamin D have skyrocketed.Links:Vitamin D: Boning up on the sunshine vitamin - news story from the CBC websiteCancer Study Boosts Vitamin D Sales - news story from the CBC websiteCanadian Cancer Society Vitamin D Recommendation - Press Releasehttp://feeds.feedburner.com/blogspo... SHR Medical Library blogs http://www.medworm.com/rss/comments.php?id=677007 Tue, 12 Jun 2007 20:08:00 +0100 677007 http://www.medworm.com/index.php?rid=611076&cid=t_90012_85_f&fid=34662&url=http%3A%2F%2Fscienceblogs.com%2Fdrcharles%2F2007%2F05%2Fthe_good_news_and_the_bad_news.php The vaccine against human papillomavirus has become somewhat of a rockstar. The CDC and major advisory councils are recommending it. Some state legislatures are voting to make its administration to young girls mandatory. Women's rights groups are generally behind the cause of vaccination as another empowerment for women's bodies. Opportunists are selling t-shirts. Conservative groups are predictably rallying against the vaccine, worried that it will lead to increased promiscuity ala their fears over the condom, the bikini, and Elvis. But is the rockstar really as good as its billing touts? Maybe. Read the rest of this post... | Read the comments on this post... (Source: The Examining Room of Dr. Charles) The Examining Room of Dr. Charles blogs http://www.medworm.com/rss/comments.php?id=611076 Thu, 10 May 2007 18:23:25 +0100 611076 http://www.medworm.com/index.php?rid=554444&cid=t_90012_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F04%2F19%2Fno-food-no-problem%2F This study evaluated the safety for individuals with type 1 diabetes and to identify factors associated with success. Patients intending to fast were instructed on insulin dose adjustments, frequent glucose monitoring and when to terminate the fast. The study included 56 subjects who intended to fast -- 37 successfully completed the study. Individuals terminated their fast in the presence of either hypoglycaemia or hyperglycaemia. Overall, adherence to the protocol was high. Successful fasters had greater reductions in insulin dosage and higher HbA1c levels. There were no differences between individuals taking intermittent insulin injections and those with continuous infusion pumps. There were no serious side-effects of fasting. Results concluded that type 1 diabetics can successfully par... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=554444 Thu, 19 Apr 2007 04:00:00 +0100 554444 http://www.medworm.com/index.php?rid=488689&cid=t_90012_85_f&fid=34662&url=http%3A%2F%2Fscienceblogs.com%2Fdrcharles%2F2007%2F03%2Fno_more_duct_tape_for_warts.php From the Archives of Dermatology (as summarized in Journal Watch): In a study receiving extensive media attention, duct tape performed no better than placebo at treating warts in adults. Researchers randomized 90 patients -- with average wart duration of about 10 years -- in double-blind fashion to receive moleskin and transparent duct tape (intervention) or moleskin alone (control) wrapped around their warts. By 2 months, roughly 20% of patients in both groups had resolution of the target wart. Writing in the Archives of Dermatology, the authors identify possible reasons their results differ from an earlier study of duct tape in pediatric patients, including the age differences between the two populations and the fact that, for blinding purposes, they used transparent duct tape in t... The Examining Room of Dr. Charles blogs http://www.medworm.com/rss/comments.php?id=488689 Wed, 21 Mar 2007 12:50:42 +0100 488689 http://www.medworm.com/index.php?rid=462689&cid=t_90012_85_f&fid=34662&url=http%3A%2F%2Fscienceblogs.com%2Fdrcharles%2Fupload%2F2007%2F03%2Fmouse.jpg When we consider the common house mouse, we often conjure tales of frantic housewives and brooms, or perhaps the more benign Christmas mouse (which does not even stir on Christmas Eve). But according to ongoing research, the common house mouse may be a player in a much more nefarious tale - that of breast cancer in women. Growing evidence suggests that breast cancer may be partly caused by infection with a retrovirus known as human mammary tumor virus (HMTV). It is closely linked to mouse mammary tumor virus (MMTV) which causes breast cancer in mice. MMTV and HMTV are 95% genetically identical, and MMTV is known to jump species. Mus domesticus, the common house mouse, has been a commensal pest with formerly nomadic humans since the dawn of farming and those permanent settlements we call ... The Examining Room of Dr. Charles blogs http://www.medworm.com/rss/comments.php?id=462689 Fri, 09 Mar 2007 14:17:28 +0100 462689