MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'cystic fibrosis'. Sat, 03 Sep 2011 02:03:10 +0100 http://www.medworm.com/index.php?rid=5062499&cid=t_131195_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2F_zpfd5XXIyY%2F Early next year, a drug for cystic fibrosis is expected to be reviewed by the FDA and it is a moment the Cystic Fibrosis Foundation has been waiting years to occur. The non-profit has invested $75 million and approval of the drug - which was developed by Vertex Pharmaceuticals with support from the foundation - would provide a new treatment for patients. And CFF will get a new revenue stream. Why? As Nature writes: CFF has a stake in the intellectual property underlying the drug and is entitled to royalties. So-called venture philanthropy is increasing among foundations, which are managing research projects, making funding dependent on projects reaching predetermined milestones and potentially reaping a return. They are also trying to keep control in the event obstacles emerge. Not surpris... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=5062499 Mon, 25 Jul 2011 14:59:40 +0100 5062499 http://www.medworm.com/index.php?rid=4841485&cid=t_131195_88_f&fid=38129&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Flifeinthefastlane%2FWZHV%2F%7E3%2FgebRDS6VN2s%2F Patients are often a source of inspiration and hope. One such stand out individual is Nathan Charles. (Source: Life in the Fast Lane) Life in the Fast Lane blogs http://www.medworm.com/rss/comments.php?id=4841485 Thu, 19 May 2011 01:47:55 +0100 4841485 http://www.medworm.com/index.php?rid=4658627&cid=t_131195_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2Fz32nDiD2ons%2F Good morning, everyone. How are you today? A busy agenda awaits us here on the Pharmalot corporate campus, where we have a pile of meetings and deadlines to attack. We trust you can relate. To cope, yes, we are downing a cup or two of stimulation. As always, we invite you to join us. And to get you started, here are some tidbits from the world at large. Hope your day goes well and do stay in touch… Sonova Execs Resign After Insider Trading Probe (Bloomberg News) Gilead And Yale Former Cancer Research Deal (Reuters) Valeant Offers To Buy Cephalon For $5.7 Billion (Bloomberg News) Glaxo’s Lovaza Partner Pronova Settles Patent Row With Apotex (Reuters) UK’s NICE Rejects Bristol-Myers’ Orencia Drug (Dow Jones) Vertex CF Drug Shows Promising Results (Mass High Tech) Merc... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4658627 Wed, 30 Mar 2011 11:41:48 +0100 4658627 http://www.medworm.com/index.php?rid=3529786&cid=t_131195_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fwhen-a-patient-outgrows-a-childhood-disease%2F2010.05.04 At a [recent] session on caring for adult survivors of pediatric diseases, Bradley J. Benson, FACP, and Niraj Sharma, FACP, had some interesting statistics to share. For example, more than 90% of children with a chronic or disabling health condition are expected to live more than 20 years, meaning they’ll eventually need an internist’s care, and every year more than 500,000 children with special healthcare needs turn 18. As Dr. Sharma noted, “We’re not talking about a handful of folks.” (more…) *This blog post was originally published at ACP Internist* (Source: Better Health) Better Health blogs http://www.medworm.com/rss/comments.php?id=3529786 Tue, 04 May 2010 14:00:00 +0100 3529786 http://www.medworm.com/index.php?rid=3443683&cid=t_131195_87_f&fid=38368&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FDisruptiveWomenInHealthCare%2F%7E3%2Fd1P7Gpd4uCk%2F Beth Sufian is one of the oldest survivors of Cystic Fibrosis. As an attorney, the Houstonian has fought for the medical rights of thousands of patients — even from her own hospital bed — and travels the country teaching parents how to advocate for their children. She took a few minutes to talk with Disruptive Women’s Wendy Grossman. Q: You’ve dedicated your career to fighting for people living with CF. A: Yes. Q: Can you tell me a little bit about your work? A: Working with CF is about half of what I do — the other half is serious medical conditions. Q: Like what? A: I run a hotline for people with CF from all over the country to call and get information about health insurance and benefits and rights and employment. We’ve been in existence since 1998, and w... Disruptive Women in Health Care blogs http://www.medworm.com/rss/comments.php?id=3443683 Wed, 07 Apr 2010 12:17:26 +0100 3443683 http://www.medworm.com/index.php?rid=3420565&cid=t_131195_111_f&fid=39123&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fnursingcomments%2Ftdtc%2F%7E3%2FxU95Ht2k1g4%2F           Cystic fibrosis or CF is an inherited disease involving epithelial cells.  Epithelial cells are found lining the skin, sweat glands, and respiratory, gastrointestinal and genitourinary tracts.  In people with cystic fibrosis, the epithelial cells do not function properly.  These impaired cells cause abnormal regulation of the flow of salts and water.  The result is abnormal secretions such as a thick, sticky mucus that clogs the lungs.  It is a life-threatening disorder that causes severe lung damage and nutritional deficiencies.  The affected gene, which is inherited from a child’s parents, is a recessive gene.  With recessive genes, children need to inherit two copies of the gene, one from each parent, in order to have the disease.  If children inherit on... Nursing Comments blogs http://www.medworm.com/rss/comments.php?id=3420565 Wed, 24 Mar 2010 11:02:58 +0100 3420565 http://www.medworm.com/index.php?rid=3390713&cid=t_131195_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F03%2F22%2Farchives-of-dermatology-2010-vol-146-no-2%2F Contents page Fade Fave: Cystic Fibrosis Presenting With Dermatitis Fade Skinny: Given the frequent delay in diagnosis, as well as the increased morbidity and mortality associated with protein-energy malnutrition in these patients, it is important to consider cystic fibrosis as a possible diagnosis in any infant presenting with a rash and other signs of malnutrition. The relative contribution of specific nutritional deficiencies and the degree to which they influence and interact with each other in producing the dermatitis remain unclear, although they may all affect a common underlying metabolic pathway. (NHS Athens is required to access this article online) Filed under: Athens Password, Current Awareness, E-Journals, Journals Tagged: Athens Password, CF, Current Awareness, Cystic Fibro... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3390713 Mon, 22 Mar 2010 10:42:09 +0100 3390713 http://www.medworm.com/index.php?rid=2725170&cid=t_131195_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FmAHdOFzlaMI%2F Antibiotics are normally used to treat the wide variety of bacterial infections, however they are ineffective against viruses (like the flu and colds) and fungal infections. And while genetic diseases can be treated with therapy and proper management, the gene will always be defective. AND, antibiotics are not known or normally used to treat genetic defects. Well, this antibiotic may be the exception. Israeli scientists have modified a potent antibiotic that may allow it to treat cystic fibrosis and other genetic diseases caused by “stop mutations”. The anti-bacterial antibiotic gentamicin is one of the highly toxic antibiotics called aminoglycosides that  doctors only use when less powerful drugs prove ineffective. but gentamicin is extremely toxic and lethal when taken long te... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2725170 Fri, 21 Aug 2009 12:14:00 +0100 2725170 http://www.medworm.com/index.php?rid=2588195&cid=t_131195_87_f&fid=36069&url=http%3A%2F%2Ffrankiespeakingfrankly.blogspot.com%2F2009%2F07%2Fswine-flu-recuperation.html Today I feel better. Yesterday after posting that I was on the mend I then seemed to take a turn for the worse - my temperature started to rise again, I developed pain across one side of my chest, started to sweat a lot and sensed my cough was changing into something maybe worse. So after 10 days of fighting this thing and feeling completely exhausted, I accepted it was about time to start antibiotics since my infection was likely turning bacterial. I started to read about pneumonia and decided I didn't want to take the risk.I then started to worry about my father who seemed worse than myself and not really getting better either. I called my mother and insisted that she call the doctor the next morning whether he agreed or not. My father, in the typical British manner, prefers to struggle ... Frankie Speaking Frankly blogs http://www.medworm.com/rss/comments.php?id=2588195 Thu, 09 Jul 2009 21:22:00 +0100 2588195 http://www.medworm.com/index.php?rid=2382685&cid=t_131195_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F0fnUw1d66vc%2F Ashkenazi Jews are known to have an average IQ between 107-115, putting half of the ethnic group into the genius range. Unfortunately, Ashkenazi Jews are also plague with genetic diseases! One fourth of the population is a carrier of one of several genetic conditions, which include Tay-Sachs Disease, Canavan, Niemann-Pick, Gaucher, Familial Dysautonomia, Bloom Syndrome, Fanconi anemia, Cystic Fibrosis and Mucolipidosis IV. A “carrier” for a gene means that the person carries only one copy of the gene. The gene is not expressed in that person’s trait or phenotype. However, marrying another carrier or someone with two copies of the gene may produce children with the trait. For example, a carrier for blue eyes may have a different eye color but has children with blue eyes. When talk... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2382685 Sun, 03 May 2009 04:27:25 +0100 2382685 http://www.medworm.com/index.php?rid=2365162&cid=t_131195_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F3408TIqVfgc%2F “Two lungs are better than one - when it comes to lung transplantations,” thanks to a new study that looked at the long-term survival rates of patients who had lung transplants. Lung transplantation may be an option for people with cystic fibrosis , emphysema, idiopathic pulmonary fibrosis , or sarcoidosis , although there may be other illnesses in the group as well. The study, done by researchers from Johns Hopkins, found that having both lung replaced by healthy lungs because if one lung is left behind, there may be some residual (left over) parts of the disease, which could end up causing problems. The researchers also point out that “when both lungs are replaced, the new lungs, which must breathe together as a pair, are already adapted to each other.” The encour... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2365162 Thu, 23 Apr 2009 11:53:54 +0100 2365162 http://www.medworm.com/index.php?rid=2323426&cid=t_131195_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FLmqN9HEpWLc%2F Some men have more success than others in producing children, genetically speaking, that is. Large European family, circa 1950s. New findings have identified a gene that endows some men more reproductive prowess than their neighbor, according to an article by The Scientist. And the secret is a switch in amino acids within one gene – from an amino acid called methionine to valine. Carole Ober of the University of Chicago, presented her findings at the Sackler Colloquium on Evolution in Health and Medicine in Washington, DC and she found that “men who carried two copies of the valine allele were 2.6 times more likely to conceive than men with two copies of the methionine allele at the same locus”. Man, that’s double the advantage! The gene in the spotlight? CFTR, or cystic fibrosis t... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2323426 Wed, 08 Apr 2009 14:04:00 +0100 2323426 http://www.medworm.com/index.php?rid=1829055&cid=t_131195_87_f&fid=34825&url=http%3A%2F%2Fwww.wesleyjsmith.com%2Fblog%2F2008%2F09%2Fgenetically-altering-pigs-to-find-cure.html This is an example of how animal research can lead to tremendous alleviation of human suffering. Pigs are being genetically altered to have CF and cloned for use in research. From the story:Cystic fibrosis (CF) is triggered when a person inherits two copies of a faulty gene carried by about one in 25 of the population. The disorder causes widespread damage to internal organs, especially the lungs and gut, by clogging them with thick, sticky mucus.Now a team at the University of Missouri has developed a pig which appears to closely mimic the disease. The striking similarities suggest that the pigs will help improve understanding and may also speed discovery of new treatments.Animal rights activists would say that the pigs lives are as important and valuable as all those people with cystic f... Secondhand Smoke blogs http://www.medworm.com/rss/comments.php?id=1829055 Fri, 26 Sep 2008 04:45:00 +0100 1829055 http://www.medworm.com/index.php?rid=1711832&cid=t_131195_134_f&fid=36049&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FDiabetesNotes%2F%7E3%2FxtpddU9lR8g%2F Doctors have found that 80 per cent of Tasmanians with cystic fibrosis over the age of 18 have diabetes. Cystic fibrosis is a disease of the mucous and sweat glands. There is hopes that this discovery will increase life expectancy. “They are now put on to insulin once or twice or four times a day and we are seeing benefits in their lung function, their weight is going back up and they are, we hope, going to do better for longer,” he said. via ABS News    Tags: connection between the diseases, cystic fibrosis, Diabetes, linkShare This (Source: Diabetes Notes) Diabetes Notes blogs http://www.medworm.com/rss/comments.php?id=1711832 Sun, 17 Aug 2008 18:49:31 +0100 1711832 http://www.medworm.com/index.php?rid=1709713&cid=t_131195_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2008%2F08%2Fby-secretary-or-by-professional-report.html A recent study caught my eye. Done by multiple centers..... from the Division of Laboratory Systems,* Centers for Disease Control and Prevention, Atlanta, Georgia; the Wadsworth Center, New York State Department of Health, Albany, New York; the Albert Einstein College of Medicine, New York, New York; ARUP Laboratories and the University of Utah, Salt Lake City, Utah; the Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington; San Ramon Valley Primary Care, San Ramon, California; the Genetic Services Laboratory,** Sequenom Incorporated, San Diego, California; and the Department of Human Genetics, Mount Sinai School of Medicine, New York, New York.What did they investigate? Simple....how genetic tests were orderded and how results were given. What really g... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=1709713 Thu, 14 Aug 2008 15:31:00 +0100 1709713 http://www.medworm.com/index.php?rid=1354217&cid=t_131195_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F265595218%2F In addition to raising venture capital and launching stock offerings, Massachusetts biotechs are increasingly turning to another source of funding to support early drug research: nonprofit foundations dedicated to fighting serious diseases, The Boston Globe writes. For instance, the Cystic Fibrosis Foundation, has awarded more than $300 million to for-profit companies over the past decade to help develop cutting-edge therapies, including $192 million in the Boston area. Epix Pharmaceuticals is receiving up to $37 million, in addition to about $12 million it has already received, to help discover new cystic fibrosis drugs. The money is contingent on Epix’s meeting certain goals. Other foundations are following suit. For example: The Juvenile Diabetes Research Foundation said it has gi... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1354217 Mon, 07 Apr 2008 11:12:59 +0100 1354217 http://www.medworm.com/index.php?rid=1275094&cid=t_131195_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F244951595%2F This article was published on Highlight HEALTH. Related articlesHEALTH Highlights - Monday, December 10thHEALTH Highlights - August 21st, 2007HEALTH Highlights - June 1st, 2007HEALTH Highlights - January 14, 2008The Highlight HEALTH Network (Source: Highlight HEALTH) Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1275094 Mon, 03 Mar 2008 17:01:43 +0100 1275094 http://www.medworm.com/index.php?rid=1170147&cid=t_131195_134_f&fid=36049&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FDiabetesNotes%2F%7E3%2F221013906%2F The 1,000 Genomes Project, which is launched today by an international consortium of scientists, aims to identify every genetic variant that is carried by at least 1 per cent of the human race, to unlock how these influence health. When the map is complete in two years’ time, it will include the complete genetic codes of more than 1,000 individuals, providing an index to the human genome that will significantly enhance medical research. This medical research will enhance our knowledge of diseases like diabetes and cystic fibrosis. It is said that all humans are more than 99% similar at the genetic level and it is that 1% variant that explains differences in peoples susceptibility to chronic diseases, medications and infections. This is a very exciting project and is truthfully mind blowi... Diabetes Notes blogs http://www.medworm.com/rss/comments.php?id=1170147 Tue, 22 Jan 2008 14:27:55 +0100 1170147 http://www.medworm.com/index.php?rid=728750&cid=t_131195_149_f&fid=35780&url=http%3A%2F%2Fwalkerma.wordpress.com%2F2007%2F05%2F15%2Frescuing-mutated-genes-as-potential-therapy%2F It’s rare that a disease or disorder can be attributed to a single mutation in a gene let alone to a single gene but in certain cases such as in Cystic Fibrosis and Rett syndrome this is exactly what happens. If you were able to find the gene that was responsible for such a disease you might think that you were well on the way towards developing a treatment or cure, but this has proved not to be the case.  The problem lies in the fact that the mutations that are often associated with disease usually lead to “silencing” of a vital protein, be it an enzyme or receptor, meaning that the protein is non-functional or is not expressed at all. Medicinal chemistry is only good at modulating (ie. inhibiting or activating) proteins that work normally so there is a fundamental... one in ten thousand blogs http://www.medworm.com/rss/comments.php?id=728750 Tue, 15 May 2007 17:32:41 +0100 728750