MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'dengue fever'. Sat, 03 Sep 2011 02:21:42 +0100 http://www.medworm.com/index.php?rid=5028218&cid=t_141286_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fdengue-fever-mosquito-born-illness-now-found-in-texas-florida-and-hawaii%2F2011.07.13 Dengue fever is a viral (flavivrus) disease transmitted by Aedes albopictus and female A. aegypti mosquitoes. It is estimated that 50 to 100 million people in more than 100 countries are infected each year with dengue viruses. There are four different types of dengue virus, and there is no cross-immunity, so a person may be stricken with dengue fever four times in his life. The most active feeding times for dengue vector mosquitoes is for a few hours after daybreak and in the afternoon for a few hours just after dark (dusk). As opposed to the night-feeding mosquitoes that transmit malaria, these species tend to be “urban,” may also feed during daylight hours (also indoors, in the shade, and during overcast weather), and are known to bite below the waist. Dengue fever is seen chiefly in... Better Health blogs http://www.medworm.com/rss/comments.php?id=5028218 Wed, 13 Jul 2011 22:00:00 +0100 5028218 http://www.medworm.com/index.php?rid=3975407&cid=t_141286_46_f&fid=38787&url=http%3A%2F%2Fmsf.ca%2Fblogs%2Fphotos%2F2010%2F09%2F16%2Fhonduras-2%2F Due to an alarming increase in the number of dengue cases in Honduras this year, Medecins Sans Frontieres (MSF) has launched an emergency intervention in Tegucigalpa, the capital of Honduras, where the highest rate of affected people has been reported. In addition to providing medical care, MSF is fighting the dengue outbreak with ‘vector control’. This means tackling the mosquitoes that spread the disease. MSF mobile teams fumigate the houses, with the aim of breaking the mosquitoes’ cycle of reproduction. MSF plans to fumigate 4,400 houses during this intervention. Families and pets must leave their houses while the fumigation team works, and they have to wait half an hour before re-entering. (Source: MSF Blogs) MSF Blogs blogs http://www.medworm.com/rss/comments.php?id=3975407 Thu, 16 Sep 2010 09:00:56 +0100 3975407 http://www.medworm.com/index.php?rid=3822849&cid=t_141286_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2010%2F08%2Fdengue-fever-outbreak-florida%2F Dengue fever, a tropical infectious disease carried by mosquitoes is making a comeback in Florida. Two species of insect – Aedes aegypti and Aedes albopictus have caused 34 cases this summer. (Source: Inside Surgery) Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=3822849 Wed, 04 Aug 2010 22:43:12 +0100 3822849 http://www.medworm.com/index.php?rid=3776613&cid=t_141286_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2Fk-LiTj0Ymho%2F Hello, everyone. Sincere apologies for the delayed start, but we were experiencing those ubiquitous technical difficulties that can stop you dead in your tracks. Nonetheless, we are soldiering on. And so here are a few tidbits that you may have missed. Meanwhile, we are reaching for yet another cup of stimulation to compensate for the disturbances. Hope your day goes well… Merck Buys Vaccine Unit From Hawaii Biotech (Honolulu Star-Advertiser) Glaxo Takes New AIDS Drug To Final Test Stage (Reuters) Lilly Closes $180M Deal For Alnara Pharmaceuticals (Associated Press) Teva Agrees To End IP Suit Over Aricept Patent (Law360) FDA Accepts MannKind Resubmission For Affrezza (PharmaTimes) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3776613 Wed, 21 Jul 2010 14:23:13 +0100 3776613 http://www.medworm.com/index.php?rid=2751363&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F09%2Fpassive-immunotherapy-for-dengue-fever.html Dengue is currently endemic in more than one hundred countries around the world. It causes approximately 50-100 million infections annually, including 250,000-500,000 cases of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). According to the World Health Organization (WHO), two fifths of the world population is at risk of dengue virus (DENV) infection. It has been suggested that globalization and climate change have had a significant impact on the emergence of DENV in new areas. No vaccine or therapy against DENV is currently approved for use in humans, and alternative strategies to control DENV infection are urgently needed, particularly because the design of such strategies may also inform efforts in vaccine design. Current research focuses on the prophylaxis/therapeutic potenti... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2751363 Tue, 01 Sep 2009 11:06:00 +0100 2751363 http://www.medworm.com/index.php?rid=2751365&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F09%2Fnovel-therapeutic-approaches-for-dengue.html Dengue has emerged as the most common mosquito-borne viral disease of humans in the past three decades. There are no available vaccines or antivirals against DENV. Currently, vector control is the only method for prevention of the disease. Development of a successful vaccine would require for it to be effective against all four DENV serotypes, economical, and provide long-term protection. Antivirals directed against one or more stages of the virus life cycle are likely to form an important part of dengue disease therapeutics. The strategies that have been used in the past towards development of an effective antiviral against dengue, as well as those being employed currently are discussed in light of information from structural biology, computational biology and molecular virology, highligh... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2751365 Tue, 01 Sep 2009 10:59:00 +0100 2751365 http://www.medworm.com/index.php?rid=2751368&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F09%2Fdengue-virus-vaccine-development.html A safe and effective vaccine for the control of Dengue Virus disease is urgently needed and long overdue. Because each of the four dengue virus serotypes can cause the full spectrum of dengue disease, vaccination must protect against each serotype. An unprecedented number of vaccine candidates are in development and under clinical evaluation, with live attenuated vaccines being the most advanced. Considerable effort is also being made in the development of inactivated, subunit protein, virus vectored, and DNA vaccine candidates. The need to elicit protective immunity without predisposing for antibody-mediated enhanced disease, the need for rapid and tetravalent protection, and the need for an economical vaccine have presented challenges in the development pathway. Nevertheless, innovative ... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2751368 Tue, 01 Sep 2009 10:57:00 +0100 2751368 http://www.medworm.com/index.php?rid=2751370&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F09%2Fdengue-virus-mosquito-interactions.html Dengue/dengue hemorrhagic fever is the most important vector-borne viral disease globally, with over half of the world's population living at risk of infection. While vaccines for other flaviviruses such as yellow fever, Japanese encephalitis and tick-borne encephalitis have been developed, dengue vaccine development is complicated by the need to incorporate all four virus serotypes into a single formulation. The only way to prevent dengue transmission presently is to reduce the vector population. Research focuses on the latest information on mosquito-dengue virus interaction, with the overall goal of identifying areas of research where improved understanding would likely contribute to our ability to predict and prevent cyclical epidemics.from Eng-Eong Ooi and Duane J. Gubler in Frontiers ... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2751370 Tue, 01 Sep 2009 10:55:00 +0100 2751370 http://www.medworm.com/index.php?rid=2751373&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F09%2Fmodulation-of-antiviral-response-by.html Dengue Virus (DENV) produces a wide range of human illness, ranging from asymptomatic infections to hemorrhagic and potentially fatal disease. Severe disease is associated with high viremia, immune enhancement of sequential infections, and exacerbated inflammatory response. DENV is sensed in mammalian cells by endosomal and cytoplasmic receptors and stimulates the type-1 interferon (IFNα/ β) response. Secreted IFNα/ β stimulates JAK/STAT signaling, which results in the activation of IFNα/ β- stimulated genes that lead the infected cells toward the establishment of an antiviral response. Genomic technology has enabled the identification of a remarkable list of genes induced in human host cells in response to DENV infection. The results define antiviral and pro-inflammatory responses m... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2751373 Tue, 01 Sep 2009 10:53:00 +0100 2751373 http://www.medworm.com/index.php?rid=2751375&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F09%2Fdengue-virus-replication.html As for all plus-stranded RNA viruses, dengue virus (DENV) genomic RNA is infectious. Transfection of full length DENV RNA genome into a susceptible cell triggers a complete cycle of viral replication. Construction of cDNA clones together with reverse genetics has proven to be a valuable tool to uncover genetic determinants of viral replication and to understand the function of the viral untranslated regions (UTRs). Translation initiation and initiation of RNA synthesis occur at the 5' and 3' terminal regions of the genome, respectively, and rely on complex RNA-RNA and RNA- protein interactions. The DENV 5'UTR contains two defined RNA structures, Stem-Loop A and Stem-Loop B, which have distinct functions during the process of viral RNA synthesis. The viral 3'UTR contains three domains with ... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2751375 Tue, 01 Sep 2009 10:51:00 +0100 2751375 http://www.medworm.com/index.php?rid=2751377&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F09%2Fdengue-virus-replication-complex.html Replication of all positive-stranded RNA viruses investigated so far occurs in close association with virus-induced intracellular membrane structures. Dengue virus (DENV), as a member of the family Flaviviridae, also induces such extensive rearrangements of intracellular membranes, called replication complex (RC). These RCs seem to contain viral proteins, viral RNA and host cell factors. However, the biogenesis of the RC and the three-dimensional organisation is to the most part unclear.from Sven Miller, Ines Romero-Brey, and Ralf Bartenschlager in Frontiers in Dengue Virus ResearchFurther reading: Dengue VirusFull range of books on microbiology at Microbiology Books (Source: Microbiology Blog: The weblog for microbiologists.) Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2751377 Tue, 01 Sep 2009 10:49:00 +0100 2751377 http://www.medworm.com/index.php?rid=2751380&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F09%2Fflaviviruses-translation-and-processing.html Positive strand RNA viruses, including flaviviruses, generally utilize the translational machinery of the host to synthesize viral proteins either in a cap-dependent or cap-independent manner to produce polyprotein precursors which are then processed into mature proteins. Polyprotein processing is accomplished by the concerted action of host and viral proteases. While some viruses, such as the hepatitis C virus code for more than one protease to perform distinct functions, flaviviruses code for a novel two-component serine protease which participates in early and late stages of the viral life cycle.from R. Padmanabhan and Alex Y. Strongin in Frontiers in Dengue Virus ResearchFurther reading: Dengue VirusFull range of books on microbiology at Microbiology Books (Source: Microbiology Blog: T... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2751380 Tue, 01 Sep 2009 10:43:00 +0100 2751380 http://www.medworm.com/index.php?rid=2297640&cid=t_141286_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F03%2Fdengue-virus.html Dengue virus (DENV), a mosquito-borne flavivirus, is the causative agent of dengue fever, currently one of the most significant emerging disease challenges to global public health. Although dengue is an old disease, recent decades have seen an unprecedented increase in the geographic range, incidence, and severity of infection. The virus infects 100 million people annually and is endemic in many tropical and sub-tropical regions in the world. At present, neither a licensed vaccine nor anti-viral drugs are available to control dengue disease, prompting a plethora of research initiatives aimed at understanding the molecular and cellular virology, genomics, and evolution of this important virus.Further reading: Frontiers in Dengue Virus ResearchFull range of books on microbiology at Microbiol... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2297640 Wed, 25 Mar 2009 14:33:00 +0100 2297640 http://www.medworm.com/index.php?rid=1886391&cid=t_141286_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D4934 This is what the Health Minister is saying in the press. Only 30% of dengue patients seek help within the first three days of falling ill, making it harder for the authorities to control the spread of the illness. Health Minister Datuk Liow Tiong Lai said the delay in detecting dengue cases had made it tougher for the authorities to implement effective control measures, such as fogging. The problem with this scenario is making a diagnosis of dengue fever in the first three days of having fever is extremely difficult as it is indistinguishable from any other severe viral fever. One may suspect it in a patient with fever, headache and bodyaches (but hey, that could be just a case of ‘flu for instance) but the typical rash won’t appear till about the fifth day of the illness. Pla... Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=1886391 Thu, 16 Oct 2008 04:00:00 +0100 1886391 http://www.medworm.com/index.php?rid=1114452&cid=t_141286_87_f&fid=35052&url=http%3A%2F%2Fwomensbioethics.blogspot.com%2F2007%2F12%2Fglobal-warming-spreads-tropical-disease.html (Source: Women's Bioethics Blog) Women's Bioethics Blog blogs http://www.medworm.com/rss/comments.php?id=1114452 Mon, 24 Dec 2007 00:07:00 +0100 1114452 http://www.medworm.com/index.php?rid=811316&cid=t_141286_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F146262652%2F As dengue fever increasingly becomes a disease of the affluent, especially in Asia, drugmakers are showing more interest in developing treatment, according to a recent report in Nature (subscription required). Dengue fever, a mosquito-transmitted disease that causes severe fever accompanied by joint and muscle pain, infects at least 50 million people a year in more than 100 countries, mostly in the tropics. But unlike many developing world diseases, dengue affects people at all levels of income. “This is not a disease of the poverty-stricken, rural farmer,” Scott Halstead, scientific director of the Pediatric Dengue Vaccine Initiative in Seoul told Nature. In some developing countries, “the richer you are, the more likely you are to get dengue.” And the weather the... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=811316 Mon, 20 Aug 2007 21:33:23 +0100 811316