MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'developments'. Sat, 03 Sep 2011 02:31:10 +0100 http://www.medworm.com/index.php?rid=4631565&cid=t_143228_129_f&fid=27216&url=http%3A%2F%2Flifewithadhd.com%2Fadhd-research%2Fresearch-for-adhd-latest-developments.php The FDA is still worried about the effects of certain ADHD medications on children who are at risk. Latest research does not seem to offer any reassurance or hope. The latest news is that in the long term ADHD medications seem to offer little benefit. Their efficacy seems to be reduced to the short term alleviation of ADHD symptoms such as behavioural problems, over excitability and disruptive behaviour. Medical authorities are still worried about the ease with which prescriptions of antipsychotics are written by doctors. Research for ADHD is now concentrating on the causes of ADHD but also on the safety of ADHD medications. It should also be looking at ADHD natural and homeopathic cures but, given the world we live in, I think that is a faint hope ! Latest research on ADHD has homed in on... Life With ADHD blogs http://www.medworm.com/rss/comments.php?id=4631565 Thu, 24 Mar 2011 00:00:00 +0100 4631565 http://www.medworm.com/index.php?rid=4139419&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50220604%2Fkombiglyzea_xr_fdaapproved_for_adult_type_2_diabetes.php KOMBIGLYZE™ XR - product of Bristol-Myers Squibb and AstraZeneca - got US FDA approval as treatment of type 2 diabetes in adults. The first and only once-a-day metformin extended-release (XR) plus dipeptidyl peptidase-4 (DPP-4) inhibitor combination tablet offering strong glycemic control across glycosylated hemoglobin levels (HbA1c), fasting plasma glucose (FPG) and post-prandial glucose (PPG), KOMBIGLYZE™ XR is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes when treatment with both saxagliptin and metformin is appropriate. ... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=4139419 Sat, 06 Nov 2010 01:56:35 +0100 4139419 http://www.medworm.com/index.php?rid=4119514&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50220604%2Ffish_oils_may_activate_antidiabetes_genes.php © zimpenfishAccording to a new mice study led by researchers from the National Taiwan University, polyunsaturated fatty acid (PUFA) fish oils may activate genes that regulate fat cell differentiation and glucose dispersal. Published in Journal of Nutritional Biochemistry, the study suggests that supplementation with fish oils activates the transcription factor PPARγ -- a target for many anti-diabetic drugs. PPARγ (peroxisome-proliferator-activated receptor γ) is considered an important transcription factor in regulating fat cell (adipocyte) differentiation and is also known to play a vital role ... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=4119514 Tue, 26 Oct 2010 13:43:04 +0100 4119514 http://www.medworm.com/index.php?rid=3845249&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fdiabetes_and_dementia.php © DerrickTIn the absence of a cure for cognitive impairment, researchers have recently found that interventions for diabetes prevention could be an effective way of reducing dementia. Karen Ritchie, PhD (French National Institute of Health and Medical Research (INSERM) in Montpellier) and colleagues, reported in the British Medical Journal: Diabetes was one of four potentially modifiable factors that, if eliminated or improved, would reduce rates of dementia in the general population. The percentage of dementia cases that hypothetically would be avoided if ... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=3845249 Sun, 08 Aug 2010 21:53:32 +0100 3845249 http://www.medworm.com/index.php?rid=3641229&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fbecton_dickinson_launched_the_worlds_smallest_pen_needle_for_diabetics.php Photo CreditThere is a misconception among both healthcare professionals and people living with diabetes that a person's body type or body mass index (BMI) dictates whether they need a longer needle to effectively inject insulin. The fact is that recent studies have shown that shorter, thinner needles are just as effective and less painful than longer needles, helping many people living with diabetes have a better injection experience. Becton Dickinson - a global medical technology leader - has just announced the launch of ... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=3641229 Tue, 08 Jun 2010 02:40:40 +0100 3641229 http://www.medworm.com/index.php?rid=3471996&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fartificial_pancreas_for_type_1_diabetes_is_becoming_a_reality.php © adriguIn type 1 diabetes, the pancreas doesn't produce enough insulin to control blood sugar levels. Now, a study and editorial published online April 14 in Science Translational Medicine reported that a bihormonal closed-loop artificial pancreas using a computer algorithm may tighten glycemic control in patients with type 1 diabetes while lowering risk for hypoglycemia. The said study was conducted by a research team from Boston University in Massachusetts led by Firas H. El-Khatib, PhD. An automated control of blood sugar levels (like ... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=3471996 Thu, 15 Apr 2010 05:05:37 +0100 3471996 http://www.medworm.com/index.php?rid=3460354&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fnanovaccine_reverses_type_1_diabetes_in_mice.php © euthmanType 1 diabetes or juvenile diabetes is an autoimmune disease. The white blood cells called T cells attack the insulin-producing beta cells in the pancreas. Such is the case also in diseases like lupus, rheumatoid arthritis and multiple sclerosis. While scientists already know the cause of type 1 diabetes, they haven't found a way to treat autoimmunity without impairing the body's immune system. Now a nanovaccine maybe able to do just that in humans as it has already worked in mice experiments. The ... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=3460354 Mon, 12 Apr 2010 01:16:17 +0100 3460354 http://www.medworm.com/index.php?rid=3449086&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fprint_flyers_for_mecamylamine_as_treatment_for_diabetic_macular_edema.php © atomicjeepDiabetic macular edema is a complication of diabetes that, if left untreated, may result to vision impairment, blurriness, or blindness in diabetic patients. Currently, the standard of treatment for diabetic macular edema has been glycemic control, optimal blood pressure control, and macular focal/grid laser photocoagulation. A new early-stage human clinical trial has shown that a new topical drug called mecamylamine, was safe and and may offer researchers a new approach to prevent and treat diabetic macular edema. In the study published recently in ... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=3449086 Thu, 08 Apr 2010 07:32:01 +0100 3449086 http://www.medworm.com/index.php?rid=2442391&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Ftriglycerides_and_diabetic_neuropathy.php © Thirteen Of Clubs Diabetic neuropathy - a consequence of diabetes - is a condition characterized by damaged or lost nerves resulting to numbness, tingling and pain, most often in the hands, arms, le... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=2442391 Mon, 25 May 2009 08:30:23 +0100 2442391 http://www.medworm.com/index.php?rid=2381039&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fdiabetes_drug_januvia_may_trigger_pancreatitis_pancreatic_cancer.php A new study from UCLA's Larry L. Hillblom Islet Research Center found that the type 2 diabetes drug sitagliptin - sold in pill form as Januvia - could lead to a form of low-grade pancreatitis in s... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=2381039 Thu, 30 Apr 2009 13:46:20 +0100 2381039 http://www.medworm.com/index.php?rid=2376584&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fsaliva_test_noninvasive_method_to_detect_diabetes.php © juhansonin On May 15, at the American Association of Clinical Endocrinologists (AACE) 18th Annual Meeting & Clinical Congress in Houston, Texas, a new research promoting saliva test in detecting... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=2376584 Tue, 28 Apr 2009 22:20:40 +0100 2376584 http://www.medworm.com/index.php?rid=2270283&cid=t_143228_87_f&fid=36438&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FCato-at-liberty%2F%7E3%2FXYybhcwyYBE%2F You might have trouble telling which country is the world’s superpower with the world’s largest economy, and which is the still relatively poor nation attempting to push its way onto the international stage. Reports the New York Times: The Chinese premier Wen Jiabao expressed concern on Friday about the safety of China’s $1 trillion investment in American government debt, the world’s largest such holding, and urged the Obama administration to provide assurances that its investment would keep its value in the face of a global financial crisis. Speaking at a news conference at the end of the Chinese parliament’s annual session, Mr. Wen said he was “worried” about China’s holdings of Treasury bonds and other debt, and that China was watching United States economic deve... Cato-at-liberty blogs http://www.medworm.com/rss/comments.php?id=2270283 Mon, 16 Mar 2009 15:46:17 +0100 2270283 http://www.medworm.com/index.php?rid=1980905&cid=t_143228_133_f&fid=35129&url=http%3A%2F%2Fwhitterer-autism.blogspot.com%2F2008%2F11%2Fdont-fretyet.html From back in the late Summer and into early AutumnI dive into the house weighed down with several tones of groceries that will pre-cook in the car if I don’t off-load them before the school run. I have approximately 20 minutes to put away the shopping, clear the decks and prepare my brain. As we only have cats, I worry unduly about the dog deposit on the lawn, as it’s evidence of a breach of security rather than an additional chore. I am in mid freezer pack when I glance out of the window to see half a dozen semi clad youthful persons, together with their cars and several miles of open sleeping bags strewn across the drive way. My daughter has returned from her latest camping expedition. Her pals are also tree hugger types, immune to skin cancer, tidiness and laundry. Bronzed flesh, s... Whitterer on Autism blogs http://www.medworm.com/rss/comments.php?id=1980905 Sun, 23 Nov 2008 07:59:00 +0100 1980905 http://www.medworm.com/index.php?rid=1518754&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fglucose_levelsregulating_gene_identified.php A collaborative study which includes the University of Southern California (USC) has identified the gene responsible for regulating glucose levels. According to Richard M. Watanabe, Ph.D., associate professor of preventive medicine and physiology & biophysics at the Keck School of Medicine of USC and co-senior author of the paper: "Elevations of blood glucose are diagnostic of diabetes. This finding demonstrates there are gene variants that are important for day-to-day regulation of glucose, but they do not appear to play a significant role in disease risk. The identification of these variants increases our basic biologic knowledge about regulation of glucose and may also be useful in future genetic studies to help discriminate between genetic variants that do or do not contribute to ... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1518754 Sat, 14 Jun 2008 08:00:00 +0100 1518754 http://www.medworm.com/index.php?rid=1396314&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fis_oral_insulin_coming_soon.php Previous researches delved into the possibility of an oral insulin. Though most awaited by patients and medical professionals alike, it just is not here yet. It seems there are too many obstacles that havn't been overcomed yet. © leafbug Now, researchers in Texas are reporting that they have found a gel-like material - polymer hydrogel - that may be able to speed up the development of oral insulin. In the report, Nicholas A. Peppas and colleagues point out acid in the stomach destroys insulin, preventing its administration by mouth. Many different research groups worldwide are searching for ways to overcome that obstacle. However, an ideal material for safe, effective oral delivery remains elusive. The new study describes a promising candidate in the form of a polymer hydrogel th... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1396314 Thu, 24 Apr 2008 13:36:19 +0100 1396314 http://www.medworm.com/index.php?rid=1362473&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fnovocellas_human_stem_cells_treat_diabetes_in_mice.php Based in San Diego, California (USA), Novocell Inc. has found a potential in their human embryonic stem cells for diabetes cure. As reported by Novocell's team of researchers in the journal Nature Biotechnology: Human stem cells transformed into nearly normal insulin-producing cells when implanted into mice, possibly offering a way to treat diabetes long-term. The researchers used human embryonic stem cells - the most powerful but the most controversial source of stem cells. "Our data provide the first compelling evidence that human embryonic stem cells can serve as a renewable source of functional insulin-producing cells for diabetes cell replacement therapies," said Emmanuel Baetge, chief scientific officer of Novocell. Yes, human embryonic stem cells are indeed the most power... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1362473 Thu, 10 Apr 2008 01:26:08 +0100 1362473 http://www.medworm.com/index.php?rid=1352752&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Ftb_vaccine_against_type_1_diabetes.php Harvard researchers is testing a already known tuberculosis (TB) vaccine against type 1 diabetes. According to Denise L. Faustman, a Harvard Medical School professor who is helping to lead the study: "Most trials trying to reverse the disease are for new-onset diabetes. This is one of the first trials actually trying to manipulate the immune system in someone who has a long-standing disease. We are using a generic drug that has been around for 80 years and has an impeccable safety profile." The said vaccine is causing low-grade inflammation, thereby preventing abnormal immune cells from destroying cells that produce insulin in the pancreas - which according to scientistss, might be a cure for type 1 diabetes. Find more details from The Harvard Crimson. See full article. Related ... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1352752 Sat, 05 Apr 2008 08:00:00 +0100 1352752 http://www.medworm.com/index.php?rid=1338082&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fvitamin_a_beneficial_against_type_1_diabetes.php First it was Vitamin D against type 1 diabetes. Now, it is Vitamin A against type 1 diabetes. Yeah, Vitamin A - the eye vitamin. High levels of vitamin A may curb the onset of type 1 diabetes by protecting against the attack of insulin-producing beta cells, according to an animal study by American scientists. It has previously been found that vitamin A and antioxidants can regulate the immune system. However, Charles Stephensen, a physiologist for the US Department of Agriculture's Agricultural Research Service (ARS), said that no one has shown the suppressive effect of vitamin A on type 1 diabetes. His study, published in the Journal of Nutrition, investigated this effect in mice and found that vitamin A consumption resulted in lower levels of tumour necrosis factor-alpha (TNF-a... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1338082 Mon, 31 Mar 2008 11:53:25 +0100 1338082 http://www.medworm.com/index.php?rid=1247940&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fstem_cell_therapy_against_diabetes_a_breakthrough.php I just saw this report at the New York Times entitled: Stem Cell Therapy Controls Diabetes in Mice. You know I have such high hopes for stem cell research, especially for the treatment and control of diabetes. According to the said report, the team from the biotechnology company Novocell and the University of Miami researchers was able to make stem cells into insulin-producing cells in mice that kept kept blood sugar at bay. "For those who say there is not much evidence that embryonic stem cells can cure diabetes, there you go," said Dr. Camillo Ricordi, director of the Diabetes Research Institute at the University of Miami, who was not involved in the research. Still, a small number of the mice developed tumors, and some experts said the cells might not be well-characterized enough f... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1247940 Thu, 21 Feb 2008 15:00:31 +0100 1247940 http://www.medworm.com/index.php?rid=1176148&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Findia_type_2_diabetes_herbal_cure_granted_patent.php In Jaipur, the diabetes medicine from Kadamb tree (Mitragyna parvifolia) leaves - developed/invented by Suresh Sharma - has been granted patent by the Controller-General of Patents, India. The composition, containing cadambine and dihydroconchonine, two types of alkaloids found in the tree, has also received an international classification number from the World Trade Organisation (WTO). The inventor of the medicine, Suresh Sharma of Jaipur, says it took him over 20 years and bankruptcy to develop the medicine which has successfully been tried on 1,300 patients suffering from Type II diabetes. When taken for a period ranging from 4-10 months, one of the quninoline alkaloids in the medicine, cadambine, removed insensitivity of insulin receptors situated in adipose tissues of the muscles ... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1176148 Fri, 25 Jan 2008 08:00:00 +0100 1176148 http://www.medworm.com/index.php?rid=1159549&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Flaziness_of_regulatory_tcells_lead_to_type_1_diabetes.php A very interesting finding has been discovered by a research team at McGill University's Department of Microbiology and Immunology. Immunoregulatory T-cells regulate our body's autoimmune reactions. According to the abovementioned research team, in some individuals, such T-cells may become ineffective and become "lazy" overtime - thereby leading to the onset of type 1 diabetes. In diabetes mellitus, or type 1 diabetes, insulin-producing beta islet cells in the pancreas are attacked and destroyed by the body's own immune system. Patients must inject insulin on a regular basis or risk diabetic shock and death, and are also at increased risk for numerous secondary health problems, including blindness, heart attack and stroke. According to Dr. Ciriaco A. Piccirillo, Canada R... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1159549 Fri, 18 Jan 2008 09:43:47 +0100 1159549 http://www.medworm.com/index.php?rid=1156809&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fcaffeine_and_type_2_diabetes.php Would caffeine be bad for diabetes control? According to this report, caffeine could interfere with the body's ability to handle blood sugar, thus worsening type 2 diabetes. The team at Duke University Medical Center in North Carolina found a strong correlation between caffeine intake at mealtime and increased glucose and insulin levels among people with type 2 diabetes. The American Diabetes Association says that at least 90 percent of the 17 million Americans diagnosed with diabetes have type 2, in which the body either does not produce enough insulin or cells ignore the insulin, which the body needs to convert food into energy. The findings are significant enough that the researchers recommend people with diabetes consider reducing or eliminating caffeine from their diets. ... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1156809 Thu, 17 Jan 2008 07:18:44 +0100 1156809 http://www.medworm.com/index.php?rid=1143497&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fstatins_and_diabetes_patients.php In a separate post, I wrote about the anti-cancer properties of statins. Statins are cholesterol-lowering drugs taken by people with cardiovascular conditions. Now, according to a study led by researchers at the Oxford-based Cholesterol Treatment Trialists' Collaboration working with colleagues in Australia, diabetes patients can benefit from statins. But researchers who pooled data on the effects of statins on almost 90,000 people found that a wide variety of patients benefited from the treatment, irrespective of the type of diabetes they had. Diabetes increases the risk of developing cardiovascular diseases and, although previous research has pointed to the potential benefits of taking statins, no researchers have examined this in detail. In the new study, scientists found tha... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1143497 Fri, 11 Jan 2008 08:00:00 +0100 1143497 http://www.medworm.com/index.php?rid=1131110&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fhormone_blocker_found_may_prevent_obesity_and_diabetes.php The hormone called gastric inhibitory polypeptide (GIP) receptor blockade has been found capable of promoting weight loss, improving insulin resistance and reversing diabetes in an animal model. GIP is a peptide hormone that is secreted in response to food. It inhibits the secretion of acids stimulates the releases insulin as part of the digestive process in response to food. It is found in a variety of tissues, including the intestine, heart, stomach, brain and in adipose (fat). While the significance of its action is largely unknown, its potent and prolonged stimulation after a high-fat diet has led researchers to speculate it may play a key role in metabolizing fat. The said study, conducted in mice, showed that blocking GIP activity using (Pro3)GIP with established, high fat die... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1131110 Sat, 05 Jan 2008 02:11:36 +0100 1131110 http://www.medworm.com/index.php?rid=1122551&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fmenin_cause_of_gestational_diabetes.php Some women develop diabetes during pregnancy (gestational diabetes) when the islets cells don't multiply and the body cannot meet the increased demand for insulin - thereby resulting to increases in blood sugar. When a woman is pregnant, she needs to produce more insulin than usual because her body is feeding more cells than normal. A hormone, prolactin, which is abundant during pregnancy, causes more pancreatic islet cells to grow in order to produce the extra insulin. A protein already known to prevent pancreatic cancer by blocking growth of pancreatic cells - called menin - may block the islet cells from multiplying in response to prolactin - resulting to gestational diabetes. Such were the discovery of researchers from Stanford University. When the researchers gave prolactin to... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1122551 Mon, 31 Dec 2007 09:11:06 +0100 1122551 http://www.medworm.com/index.php?rid=1121784&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fvitamin_a_against_type_1_diabetes.php In a laboratory mice study, Agricultural Research Service (ARS) nutrition scientists has shown (for the first time) that high levels of vitamin A can suppress development of type 1 diabetes. Common dietary sources of Vitamin A are pumpkin pie, sweet potatoes, carrots, among others...and then don't forget that Vitamin A supplements are abundantly available in the market. Blood sugar levels of the 45 mice in the experiment were taken regularly to determine onset of diabetes. At about seven months, only 25 percent of those mice eating a high-vitamin-A feed, and 33 percent of those eating grape-powder-enriched feed, had developed type 1 diabetes, while 71 percent of those on non-enriched feed had became diabetic. Differences in levels of a protein called tumor necrosis factor-alpha, ... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1121784 Sat, 29 Dec 2007 16:00:00 +0100 1121784 http://www.medworm.com/index.php?rid=1116718&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fyeastderived_glucose_tolerance_factor_gtf_potential_oral_diabetes_drug.php A substance derived from yeast - called Glucose Tolerance Factor (GTF) - has been discovered by University of Haifa researchers to have the potential in becoming an oral treatment for diabetes and its complications. According to lead researcher Dr. Nitsa Mirsky: "The substance has been effectively tested on rats and the next step is to assess its efficiency in humans. The research is now at the stage where the substance has been successfully tested on diabetic rats and was found to reduce sugar and lipids in the blood of the treated animals. The next stage of the research is to evaluate GTF efficacy in humans." Well, when GTF pass human testing, it will become a treatment as substitute treatment or in conjunction with insulin. Find more details from University of Haifa. See a... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1116718 Wed, 26 Dec 2007 08:10:14 +0100 1116718 http://www.medworm.com/index.php?rid=1112692&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fentelos_signed_agreement_with_jj_pharma_rd_for_diabetes_study.php A biopharmaceutical company utilizing sophisticated mathematical models of human biology to discover and develop new drugs that treat and cure diabetes among other conditions - Entelos - has joint forces with and has entered into an agreement with Johnson & Johnson Pharmaceutical Research & Development, L.L.C. in order to pursue studies on diabetes therapies. As stated James Karis, President and CEO of Entelos: "Finding the optimal therapies and treatment regimens for specific patient types is a key strength of our in silico disease platforms. The deal reinforces Entelos' stated strategy to enable proprietary drug development, particularly in chronic disease areas where multiple drugs, treatment choices, and large differences between patients make it difficult for health-care provi... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1112692 Sat, 22 Dec 2007 11:56:18 +0100 1112692 http://www.medworm.com/index.php?rid=1076370&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fpainless_detection_of_painful_neuropathies.php Neuropathy is a painful nerve condition that affects millions of people with diabetes (diabetes neuropathy) and other patients too! Now, scientists at University of Rochester Medical Center (URMC) (in collaboration with scientists from Lucid Technologies in Rochester in N.Y.) have demonstrated a new painless technique for detecting neuropathies. The painless technique focuses on tiny structures in the skin known as Meissner corpuscles, which encapsulate the endings of microscopic nerves in our hands, feet, and other areas. When someone tickles your feet, or lightly brushes the palm of your hand, or gives you a kiss - it's Meissner corpuscles that are detecting the touch. The tiny structures act like little sensors, allowing us to feel light touch and pressure. ...demonstrated a ne... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1076370 Fri, 07 Dec 2007 09:15:59 +0100 1076370 http://www.medworm.com/index.php?rid=1052367&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fbest_source_of_insulinproducing_islets_for_diabetes_treatment_living_donors.php If you do not know already, islet cells - clusters of insulin-producing pancreatic cells - even from pigs, have been successfully improved the insulin levels of insulin-dependent diabetics (type 1 diabetes). Recent research reported success in transplantation of insulin-producing islet cells from pigs to human. There are even facilities that have raised or are raising healthy, disease-free pigs to meet the high demand on islet cells. Now, according to a new study in Clinical Transplantation, obtaining islet cells (clusters of pancreatic cells that create insulin) from living donors may be the best solution to the shortage of islets available for transplantation. According to study author Dr. Kwang-Won Kim: "Islet cell transplantation is the only known cure for insulin-dependent diabe... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1052367 Tue, 27 Nov 2007 10:27:56 +0100 1052367 http://www.medworm.com/index.php?rid=1018395&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Finsulin_resistance_due_to_inflammation_not_obesity.php Inflammation brought about by immune cells called macrophages are what UCSD (University of California, San Diego) School of Medicine researchers have discovered as the one leading to insulin resistance and type 2 diabetes - opposite to what has been previously associated to the said conditions: obesity. In recent years, it has been theorized that chronic, low-grade tissue inflammation related to obesity contributes to insulin resistance, the major cause of Type 2 diabetes. In research done in mouse models, the UCSD scientists proved that, by disabling the macrophage inflammatory pathway, insulin resistance and the resultant Type 2 diabetes can be prevented. Findings of the said study are published as the feature article of the November 7 issue of Cell Metabolism. Macrophages, found i... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1018395 Sat, 10 Nov 2007 10:20:23 +0100 1018395 http://www.medworm.com/index.php?rid=1003661&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fmenin_pancreatic_protein_providing_clues_to_gestational_diabetes.php Stanford University School of Medicine researchers may have a chance in elucidating the mechanism by which diabetes develops during pregnancy (gestational diabetes), in their discovered pancreatic protein called menin. The pancreatic protein menin was already known to have a role in preventing cancer in the pancreas and other organs - when menin is present it blocks the growth of pancreatic cells, thereby prevents cancer. The said finding about menin could lead to new treatments for all forms of diabetes. The study may help explain why roughly 5 percent of women develop diabetes temporarily while pregnant, a condition called gestational diabetes. That condition is a leading cause of birth defects and can predispose the child to develop diabetes later in life. We already know that ges... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=1003661 Mon, 05 Nov 2007 10:34:23 +0100 1003661 http://www.medworm.com/index.php?rid=993265&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fdiabetes_drug_diamyda_passed_phase_ii_of_type_1_diabetes_trial.php The lead diabetes drug Candidate of Diamyd Medical - Diamyd™ - demonstrated significant efficacy in preserving insulin production in those with type 1 diabetes. The results from the Diamyd™ study demonstrate that the group of 35 recently diagnosed Type 1 diabetes patients that received Diamyd™ produced approximately twice as much meal stimulated insulin (as measured by C-peptide) 15 months after the first treatment as compared to the placebo group (p ~ 0.01). Preserving insulin-production is crucial for delaying the complications associated with long-term diabetes which cost billions of dollars to treat. Diamyd™ has shown statistically significant efficacy not only in type 1 diabetes but also in the autoimmune form of Type 2 diabetes (LADA). The drug works by preserving insulin p... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=993265 Wed, 31 Oct 2007 04:14:35 +0100 993265 http://www.medworm.com/index.php?rid=987205&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fon_other_forms_of_insulin.php Insulin is mostly popular as injection. Researchers are continuously looking and working on the development of oral insulin. Researchers at The Hospital for Sick Children (SickKids) are leading the Canadian component of a multinational clinical study aimed at preventing or delaying type 1 diabetes. The Type 1 Diabetes TrialNet study will examine whether taking insulin orally can prevent or delay diabetes in people who are at risk for the disease. If you check older posts in the blog, the following talks about oral insulin: Oral Insulin Being Tested in Clinical Trials There is Hope for Oral Insulin And who can forget the popularity of inhaled insulin? Pfizer's Exubera being the most popular of them all. But there is bad news, Battle Diabetes Blog reported that Pfizer has disc... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=987205 Mon, 29 Oct 2007 12:17:14 +0100 987205 http://www.medworm.com/index.php?rid=980595&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fdiabetes_drug_januvia_has_new_fdaapproved_uses.php Approved by the FDA in October 2006, the diabetes drug by Merck - Januvia (sitagliptin) - is a prescription medicine being used as part of a treatment programme (including diet and exercise) to lower blood sugar in patients with type 2 diabetes. Januvia is administered either alone or as an adjunctive therapy with certain other drugs, such as metformin and thiazolidinediones. Januvia is a DPP-4 inhibitor: it inhibits glucagon production (the enzyme that increases blood sugar), and stimulates insulin (the enzyme that decreases blood sugar). Now, the FDA has approved new uses for Januvia: could also be used in combination with sulfonylurea and metformin, in cases when the two are not enough to control blood sugarcould be used with metformin as an initial therapy The above follow-up app... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=980595 Fri, 26 Oct 2007 12:37:23 +0100 980595 http://www.medworm.com/index.php?rid=974361&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fdiabecell_capsule_update_on_the_pig_islet_cells_against_diabetes_research.php If you search this blog for pig islet cell transplantation, the following entries will be generated: Pig Islet Cell May Help Solve Diabetes Problem Lab-grown Insulin-producing Cells: A Breakthrough in Diabetes Research Could Pigs be the new soldiers in fighting diabetes? Pig islet cell transplantation (the correct term being xenotransplantation) is a process wherein insulin-producing pig islet cells are transplanted into humans to help with the amount of insulin that will regulate blood sugar levels. Now, here's the most recent update from the study of Melbourne scientists from a study there are conducting in Russia: A Russian woman injected with pig cells four weeks ago has not needed the regular insulin injections she had relied on to keep her type 1 diabetes in checkA second... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=974361 Wed, 24 Oct 2007 06:57:38 +0100 974361 http://www.medworm.com/index.php?rid=957329&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Ffourth_antibody_to_detect_type_1_diabetes_discovered.php Let us be reminded that type 1 diabetes (formerly called juvenile diabetes) is an autoimmune disease by which the body's immune system mistakenly targets the pancreas, killing the cells (pancreatic beta cells) that make insulin. Once the pancreatic beta cells are compromised, there won't be enough insulin in the body to control blood sugar levels. That's why those with type 1 diabetes need external source of insulin to manage their condition. There are antibodies in the human blood (three, previously identified) that are used as measures to detect predisposition (or risk level) to type 1 diabetes. The recent identification of the fourth antibody (ZnT8) will help accurately predict one's predisposition to type 1 diabetes -actually increasing the accuracy to 96 percent... Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=957329 Wed, 17 Oct 2007 11:22:05 +0100 957329 http://www.medworm.com/index.php?rid=928848&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fhormone_leptin_has_potential_role_in_diabetes.php Leptin is a hormone known mainly for regulating appetite control and energy metabolism. Now, it has been found by a new Joslin-led study to play a major role in islet cell growth and insulin secretion. According to Rohit N. Kulkarni,... Continue. (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=928848 Fri, 05 Oct 2007 08:00:00 +0100 928848 http://www.medworm.com/index.php?rid=888598&cid=t_143228_145_f&fid=35710&url=http%3A%2F%2Fksdescartin.wordpress.com%2F2007%2F09%2F20%2Fan-evening-of-more-than-the-past-present-future-part-1%2F Yesterday, September 19th was the kick off for the series of lectures at the Continuing Studies program at Rice University. It was at Sewall Hall at the Rice Campus. Dr. Denton A. Cooley, the pioneer of human heart transplant in the United States, still observably sprightly at 87, was the lecturer for the day. He is currently president and surgeon-in-chief at the Texas Heart Institute; program director for the Texas Heart Institute/Baylor College of Medicine Thoracic Residency Program; and chief of cardiovascular surgery at St. Luke’s Episcopal Hospital. Here are some of my notes on this experience. Dr. Cooley, His Influences, and The People He Worked With He performed the first successful human heart transplant in the United States in 1968. In 1969, he became the first heart surgeon to ... the story of healing blogs http://www.medworm.com/rss/comments.php?id=888598 Thu, 20 Sep 2007 19:25:33 +0100 888598 http://www.medworm.com/index.php?rid=853138&cid=t_143228_145_f&fid=35710&url=http%3A%2F%2Fksdescartin.wordpress.com%2F2007%2F09%2F09%2Fcutting-edge-developments-at-baylor-college-of-medicine-and-the-texas-heart-institute%2F I am very much looking forward to these series of lectures happening in less than a couple of weeks at Rice University. As home to the world-renowned Texas Medical Center, Houston is at the forefront of state-of-the-art medical research and development. Yet the average Houstonian may know very little about the incredible advances being made in their own backyard. In this extraordinary opportunity, doctors and researchers representing two TMC institutions, Baylor College of Medicine and the Texas Heart Institute, will address a variety of cutting-edge developments, including molecular surgery, fetal surgery and new treatments for aging and addiction. Heart surgeon Denton Cooley will kick off the lecture series with a look at the past, present and future of the TMC and its dynamic institut... the story of healing blogs http://www.medworm.com/rss/comments.php?id=853138 Sun, 09 Sep 2007 07:16:01 +0100 853138 http://www.medworm.com/index.php?rid=825517&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fsirt2_sirtuin_protein_key_in_fat_production_and_metabolism.php Sirtuin - proteins found in fat cells - may play a major role in the production and metabolism of fat, which offers new target for the development of treatments in the prevention of obesity and reduction of risk for type... Continue. (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=825517 Fri, 17 Aug 2007 12:54:54 +0100 825517 http://www.medworm.com/index.php?rid=825518&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Finflammatory_cytokines_markers_that_may_predict_type_2_diabetes_in_stillhealthy_people.php Researchers at UCLA have identified three inflammatory cytokines that will serve as molecular markers that will predict diabetes in still-healthy individuals: tumor necrosis factor-alpha (TNF-á)interleukin-6 (IL-6)high-sensitivity C-reactive protein (hs-CRP) Each one of these cytokines (or messenger molecules) may be one... Continue. (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=825518 Thu, 16 Aug 2007 08:01:06 +0100 825518 http://www.medworm.com/index.php?rid=2678811&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fmri_can_be_a_tool_in_the_diagnosis_staging_and_treatment_of_diabetes.php © Muffet A study performed at Massachusetts General Hospital and Harvard Medical School in Boston suggests that a noninvasive imaging (MRI) may aid physicians in the early diagnosis, staging and treat... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=2678811 Thu, 01 Jan 1970 00:00:00 +0100 2678811 http://www.medworm.com/index.php?rid=2657858&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fliragltuide_data_presented_at_nma.php African Americans are 1.6 times more likely to have diabetes than non-Hispanic whites, and almost 15% of all African Americans aged 20 years or older have diabetes. On top of this, despite the wide ra... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=2657858 Thu, 01 Jan 1970 00:00:00 +0100 2657858 http://www.medworm.com/index.php?rid=2512560&cid=t_143228_134_f&fid=36052&url=http%3A%2F%2Fwww.daily-diabetic.com%2F50226711%2Fvictoza_new_diabetes_drug_better_than_byetta.php © RogueSun Media Novo Nordisk has a new diabetes drug under clinical trials - Victoza (liraglutide) - that is proving much better than Byetta (exenatide). From WebMD: Byetta is the first of the clas... (Source: Daily Diabetic) Daily Diabetic blogs http://www.medworm.com/rss/comments.php?id=2512560 Thu, 01 Jan 1970 00:00:00 +0100 2512560