MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'dna genetics'. Sat, 03 Sep 2011 02:13:04 +0100 http://www.medworm.com/index.php?rid=4615331&cid=t_175863_131_f&fid=35008&url=http%3A%2F%2Fscienceroll.com%2F2011%2F03%2F21%2Fgene-expression-profiles-in-peripheral-blood-for-the-diagnosis-of-autoimmune-diseases%2F It’s a pleasure to share the great news that we just published our review in Trends in Molecular Medicine under the title, Gene expression profiles in peripheral blood for the diagnosis of autoimmune diseases. We looked at the literature and wrote about whether peripheral blood can be used for the diagnosis of autoimmune diseases or the prediction of the effectiveness of therapies. We also came up with a decision tree and a set of proposed guides in order to facilitate inter-disciplinary collaborations. The paper is not publicly available, but if you are interested, I’d be happy to send it to you via e-mail. Gene expression profiling in clinical genomics has yet to deliver robust and reliable approaches for developing diagnostics and contributing to personalized medicine. Owing... ScienceRoll blogs http://www.medworm.com/rss/comments.php?id=4615331 Mon, 21 Mar 2011 14:59:28 +0100 4615331 http://www.medworm.com/index.php?rid=4238060&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F8t7CGdV2eQ4%2F Does DNA determine if your fella cheats on you? If your guy’s a sleazebag, he may want to blame genetics. (via Vitamin G) Post from: BlissTree (Source: Genetics and Health) Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=4238060 Mon, 06 Dec 2010 21:19:57 +0100 4238060 http://www.medworm.com/index.php?rid=3223022&cid=t_175863_139_f&fid=38879&url=http%3A%2F%2Fwww.virology.ws%2F003_W3310_10.mp4 Download: .wmv (333 MB) | .mp4 (75 MB) Visit the virology W3310 home page for a complete list of course resources. (Source: virology blog) virology blog blogs http://www.medworm.com/rss/comments.php?id=3223022 Fri, 29 Jan 2010 22:00:18 +0100 3223022 http://www.medworm.com/index.php?rid=2018512&cid=t_175863_107_f&fid=36672&url=http%3A%2F%2Fwww.sciencebase.com%2Fscience-blog%2Ftop-ten-snps.html If you ever thought genetics was only about disease, then check out the popular SNPs list on SNPedia. A SNP (pronounced “snip”) is a single nucleotide polymorphism, which in BradSpeak(TM) is basically a difference in a bit of your DNA that makes you different from the rest. Anyway, here’s the Top Five SNPs that might be described as having no obvious direct medical importance. rs1815739 sprinters vs endurance athletes (I reckon I lack both) rs7495174 green eye color and rs12913832 for blue eye color rs6152 can prevent baldness (this was discovered far too late for me) rs1805009 determines red hair (some “comedians” might suggest this be swapped to the second list below) rs17822931 determines earwax (and presumably how well your ears stay clear of insect ... Sciencebase Science Blog blogs http://www.medworm.com/rss/comments.php?id=2018512 Fri, 05 Dec 2008 13:00:15 +0100 2018512 http://www.medworm.com/index.php?rid=1952957&cid=t_175863_105_f&fid=36987&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FIvorKovicMd%2F%7E3%2F449620703%2F TIME magazine picked top 50 innovations of 2008. Among them there are some related to medicine. 1. The Retail DNA Test 14. The Bionic Hand 21. The Synthetic Organism 24. Bionic Contacts 33. Biomechanical Energy Harvester 50. A Camera For the Blind (Source: Ivor Kovic, M.D.) Ivor Kovic, M.D. blogs http://www.medworm.com/rss/comments.php?id=1952957 Tue, 11 Nov 2008 15:04:41 +0100 1952957 http://www.medworm.com/index.php?rid=1334493&cid=t_175863_133_f&fid=35096&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2F259893636%2F In a new study, scientists at the University of Washington and Cold Spring Harbor Laboratories have found that rates of genetic deletions and duplications are three to four times higher in people with schizophrenia. These genetic mutations are more likely to disrupt that brain’s signaling genes, which affect brain development. Further, researchers found that “most patients have different mutations” which cause them to have schizophrenia. (While autism was once referred to as child schizophrenia, they are different diagnoses; here’s an interesting note about this at Left Brain/Right Brain.) As today’s Science Daily reports: Some deletions and duplications are common and found in all humans. The researchers studied such mutations that were found only in individu... Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1334493 Fri, 28 Mar 2008 22:17:49 +0100 1334493 http://www.medworm.com/index.php?rid=1288425&cid=t_175863_133_f&fid=35096&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAutismVox%2F%7E3%2F248045931%2F Deal in an Autism Case Fuels Debate on Vaccine is the headline for an article in today’s New York Times by Gardiner Harris about the case of Hannah Poling, the 9-year-old autistic child whose “pre-existing mitochondrial disorder…. was ‘aggravated’ by her shots,” as was conceded last week by the government in the Court of Federal Claims. Unfortunately, the New York Times does not present the full scope of the debate and makes it seem that there are two clear-cut sides, scientists and government officials, and parents of autistic children. Two officials from the CDC, Dr. Julie Geberding and Dr. Edwin Trevathan are quoted in the article, and three parents, John Gilmore of Autism United, Lyn Redwood of Safe Minds, and Rita Shreffler of the National Autism Association (NAA). Wha... Autism Vox blogs http://www.medworm.com/rss/comments.php?id=1288425 Sat, 08 Mar 2008 21:00:41 +0100 1288425 http://www.medworm.com/index.php?rid=1132178&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F212104559%2F    Male Down’s Syndrome with trisome at chromosome 21 People with Down’s Syndrome are less likey to get solid tumor cancers, research from Johns Hopkins University has revealed. Up to 95% of Down’s syndrome cases are caused by “trisomy 21″, in which the baby has three, rather than two, copies of chromosome 21, and the hundreds of genes it contains. Advances in medical management of Down’s Syndrome patients has increased life expectancy from around 30 years of age to over 60 years of age.  This increase led to some studies finding that adults with Down’s syndrome appear to have less chance of developing certain cancers which involved “solid” tumors. On mouse studies, the Johns Hopkins team pinpointed a single gene, Ets2, and found t... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1132178 Sun, 06 Jan 2008 16:13:30 +0100 1132178 http://www.medworm.com/index.php?rid=1121280&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F207949694%2F Brain cells  I just love this following article which tells us that there could be enough computing ability in just one brain cell to allow human and animals to feel! There is one question that springs to mind, though … if we have so many billion neurons each with the capability of storing vast amounts of information … why am I increasingly unable to retain the simplest of facts?  Think I need to upgrade my brain model! The brain has 100 billion neurons but scientists had thought they needed to join forces in larger networks to produce thoughts and sensations. The complexity of the human brain and how it stores countless thoughts, sensations and memories are still not fully understood. However, a research team from the Humboldt University in Germany and the Erasmus Medical... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1121280 Sat, 29 Dec 2007 09:01:28 +0100 1121280 http://www.medworm.com/index.php?rid=1114450&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F205539070%2F The University of Michigan study titled “Nature vs. Nurture in Ventral Visual Cortex: An fMRI Study of Twins has published  evidence that our brains are hardwired before birth to recognize faces and places. But in contrast, the neural circuitry we use to recognize words develops mainly as a result of experience. Professor Thad Polk, lead author of the study comments: “There’s been a big debate about whether face recognition is a function we’re wired to perform for survival. This is the first study to look at that question using brain imaging in twins.” Polk and his colleagues used functional MRI to examine brain activity in sets of identical and fraternal twins who viewed pictures of faces, houses, chairs, made-up words and abstract control images. Faces, ho... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1114450 Mon, 24 Dec 2007 09:34:30 +0100 1114450 http://www.medworm.com/index.php?rid=1100152&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F201727862%2F Men whose mothers, sisters or daughters test positive for BRCA 1 and/or 2 - the breast cancer causing gene mutations - have an increased risk of developing the disease but are often unaware of that risk.  These men face a 14 percent lifetime risk of developing prostate cancer as well as a 6 percent lifetime risk of developing male breast cancer . Much time and effort is spent advising and counseling females and their female relatives but little or no time spent with male relatives. Male blood relatives of BRCA gene carriers should speak to their physicians about organizing a regular prostate screen and a breast physical examination. Elaine Warburton Share This (Source: Genetics and Health) Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1100152 Mon, 17 Dec 2007 17:00:36 +0100 1100152 http://www.medworm.com/index.php?rid=1085651&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F198607638%2F  A sickle cell compared with with a normal red blood cell Further to my blog on retrieving stem cells from skin cells , scientists in Alabama and Massachusetts have reported a key next step when they used the stem cell technique to give mice with sickle cell anemia a healthy new blood supply. Lead researcher Tim Townes, molecular genetics chief at the University of Alabama, Birmingham, created a strain of mice bearing the human genes for sickle cell, a devastating inherited disease of deformed red blood cells that can’t carry enough oxygen. Townes paired with prominent stem cell scientist Rudolf Jaenisch of the Whitehead Institute in Cambridge, Mass., to reprogram skin from those mice into embryonic-like stem cells. They coaxed the newly engineered cells to grow into blood-producin... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1085651 Tue, 11 Dec 2007 13:24:25 +0100 1085651 http://www.medworm.com/index.php?rid=1084241&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F198270797%2F Yay!  At last common sense prevails! The UK’s Human Genetics Commission (HGC) has just issued an enormous tome on the subject of genetic testing called ‘More Genes Direct’ (recommended weekend read!) The report discusses the imminent explosion of genetic testing and the fact there is very little regulation or independent validation about test claims.  The HGC is concerned that in the wrong hands, genetic testing could do more harm than good. This has also been highlighted by the FDA but the FDA has made huge inroads in reviewing, analysing and assessing genetic tests in order to produce gold standard protocols.  This I have discovered first hand when I met them in Washington recently and they used Agendia’s Mammaprint breast cancer prognostic microarray as a... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1084241 Mon, 10 Dec 2007 22:04:16 +0100 1084241 http://www.medworm.com/index.php?rid=1084243&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F198244374%2F This blog should have been posted a while back, so apologies if appears a little behind the times! Recently James Watson and Craig Venter let it be known that they had their genomes sequenced and analysed.  Each reported their respective predispositions to various diseases. Bearing in mind it cost several $bn  to sequence the first human genome, for a cool $350K you can be one of the first to have your genome sequenced! Knome of Cambridge, Massachusettes, USA is offering 20 individuals the opportunity to have their genome sequenced.  They will have over 20,000 genes analysed and their predisposition to over 2,000 common and rare diseases assessed by a team of geneticists, clinicians and bioinformatics. For further information visit www.knome.com Elaine Warburton Share This (Source: Gene... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1084243 Mon, 10 Dec 2007 20:49:56 +0100 1084243 http://www.medworm.com/index.php?rid=1031111&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F185718392%2F Oh yes! At last research to cheer me up! I just had to write about this research by the Universities of Pittsburg and California. Women with curvy figures (like myself!) are likely to be brighter than waif-like counterparts and may well produce more intelligent offspring. The bigger the difference between a woman’s waist and hips the better.  The researchers speculated this was to do with fatty acids around their hips.  In this area the fat is likely to be Omega-3 which could improve the woman’s own mental abilities as well as her unborn child. … I’m not entirely convinced, but I can but dream! Elaine Warburton Genetics and Health correspondent www.geneticsandhealth.com Share This (Source: Genetics and Health) Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1031111 Fri, 16 Nov 2007 11:10:43 +0100 1031111 http://www.medworm.com/index.php?rid=1027132&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F184907254%2F Writing ths article has made me feel somewhat queasy but hey this is a good use of us girls monthly ‘curse’! Cryo-Cell, a US company has launched a service for women to store their own stem cells taken from their menstrual blood - as a future health insurance. It charges $499 (£238) for processing and a year’s storage.  Richard Branson’s Virgin Health Bank already offers umbilical cord blood banking for around $3,000 (£1,500). Cryo-Cell say one menstrual cycle has the potential to produce millions of stem cells but it may take several years for these menstrual stem cells to be developed into potential readily available commerical therapies. The main stem cell regulatory authorities are not impressed! Elaine Warburton Genetics and Health correspondent www.genetics... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1027132 Wed, 14 Nov 2007 22:50:45 +0100 1027132 http://www.medworm.com/index.php?rid=993226&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F177627476%2F It’s the last day of Breast Awareness month, so I thought this post would be quite apt! This year sees the tenth anniversary of the discovery of breast cancer gene BRCA2! According to estimates of lifetime risk, about 13.2% of women will develop breast cancer, compared with estimates of 36% to 85% with an altered BRCA2 gene.  So, if you have an altered BRCA2 gene you’re 3-7 times more likely to develop breast cancer than women without the gene. The groundbreaking discovery has given women with a family history of the disease real reason to celebrate with the greatest gift of all - extending lives and proactive choices about their care. For further information on the BRCA genes and BRCA testing visit: www.myriad.com and www.opaldia.com Elaine Warburton Share This (Source: Ge... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=993226 Wed, 31 Oct 2007 10:06:46 +0100 993226 http://www.medworm.com/index.php?rid=985634&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F176164320%2F The whole topic of ‘junk DNA’ fascinates me.  How can any part of DNA be considered junk?  It must have had a role at some stage. DNA is too perfect to have junk parts! I found this article in Science Daily about junk DNA and the subsequent finding that a part of it played a major role in controlling genes. Excepts of the article are as follows .. “A study by researchers at the ‘Yale Stem Cell Center’ for the first time demonstrates that piRNAs, a recently discovered class of tiny RNAs, play an important role in controlling gene function. These piRNAs are mainly derived from so -called junk DNA and had escaped the attention of generations of geneticists and molecular biologists when Haifan Lin, Director of Yale’s Stem Cell Center discovered them in mam... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=985634 Sun, 28 Oct 2007 10:24:26 +0100 985634 http://www.medworm.com/index.php?rid=972754&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F173887410%2F The Genetics and Health post on the GeneBase DNA Ancestry project provoked untold negative criticism particularly against readers who had experienced indifferent customer service and ambiguous results.  I came across this article in Medical News Today which presents findings by Prof Deborah Bolnick at The University of Texas, Austin. “Although many people rely on commercially available genetic tests for insights into their ancestry, the tests have significant limitations according to Deborah Bolnick, assistant professor of anthropology at The University of Texas at Austin.In “The Science and Business of Genetic Ancestry Testing,” which appears in the Oct. 19 issue of Science, Bolnick and 13 researchers from universities across the nation call upon the scientific commun... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=972754 Tue, 23 Oct 2007 16:28:35 +0100 972754 http://www.medworm.com/index.php?rid=950906&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F170084440%2F Good news for us early birds who grit their teeth to get through the afternoon because our evolutionary bio-rhythms are at their lowest ebb. Research by Liverpool’s John Moores University has shown that the mere thought of an afternoon siesta can help reduce the risk of a heart attack.  The length of the nap is irrelevant as it is in the minutes just before we drop off when the beneficial changes to our body take place. At this point blood pressure drops taking the strain off the heart. Next time I think about an afternoon siesta, I’ll know it’s in my genes and it’s doing me good …! Elaine Warburton Share This (Source: Genetics and Health) Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=950906 Mon, 15 Oct 2007 10:58:26 +0100 950906 http://www.medworm.com/index.php?rid=865524&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F155405477%2F Great news for those of us who love singing but are not appreciated by our family and friends who cringe at our warbling!  Blame it on being tone deaf?  Not anymore!  Apparently only 1 in 20 of us have inherited amusia, the medical term for tone deafness. Tests have shown that some people with bad singing voices hear music just fine. Amusics are a smaller group with a perceptual problem, they can’t pick out differences in pitch or follow the simplest tunes. Brain scans haven’t revealed major anatomical differences in amusics, but more sophisticated tests have uncovered some subtle variations.  It’s all to do with the density of the brain’s white matter between the right frontal lobe, where higher thinking occurs, and the right temporal lobes, where basic process... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=865524 Wed, 12 Sep 2007 08:33:22 +0100 865524 http://www.medworm.com/index.php?rid=853140&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F154144870%2F The Holocaust Museum in Houston, Texas is running a new exhibit and lecture series, “Medical Ethics and the Holocaust”.  The series is being opened by James Watson the Nobel Prize-winning scientist whose 1953 co-discovery of DNA’s structure culminated this decade in the mapping of the human genome. Watson heads an impressive roster of speakers, who include three Nobel laureates and such prominent figures as Dr. Francis Collins, the head of the Human Genome Project, and Leon Kass, the former director of President Bush’s Council on Bioethics. Topics range from pre-implantation genetic diagnosis to euthanasia in the movies to performance-enhancing drugs in sports to the United States’ history with eugenics. For further information:  http://www.chron.com/disp/st... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=853140 Sun, 09 Sep 2007 09:53:37 +0100 853140 http://www.medworm.com/index.php?rid=768993&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F139127282%2F Scientists have discovered the first gene which appears to increase the odds of being left-handed. The Oxford University-led team believe carrying the gene may also slightly raise the risk of developing psychotic mental illness such as schizophrenia. The gene, LRRTM1, appears to play a key role in controlling which parts of the brain take control of specific functions, such as speech and emotion. The study appears in the journal Molecular Psychiatry. The brain is set up in an asymmetrical way. In right-handed people the left side of the brain controls speech and language, and the right side controls emotions. However, in left-handed people the opposite is true, and the researchers believe the LRRTM1 gene is responsible for this flip. They also believe people with the LRRTM1 gene may have ... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=768993 Tue, 31 Jul 2007 08:03:07 +0100 768993 http://www.medworm.com/index.php?rid=767592&cid=t_175863_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F138855170%2F On July 24, 2007 the U.S. Food and Drug Administration (FDA) was informed by Targeted Genetics Corporation of Seattle about the death of a patient who received an investigational gene therapy product in a clinical trial for the treatment of active inflammatory arthritis. The product that was being studied uses a particle called a vector that is designed to deliver treatment genes to target cells. The vector used is a recombinant adeno-associated virus (AAV) derived vector and delivers the gene for Tumor-Necrosis Factor -Receptor, with the intent to inhibit a key mediator of inflammation. In the study, the gene therapy was administered into the joint affected by the disease to reduce inflammation and disease in patients with active inflammatory arthritis. More than 100 subjects have been en... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=767592 Mon, 30 Jul 2007 14:40:56 +0100 767592 http://www.medworm.com/index.php?rid=720430&cid=t_175863_107_f&fid=35762&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fscienceblogs%2Fgrrlscientist%2F%7E3%2F131757964%2Fmendels_garden_blog_carnival_n.php tags: DNA, genetics, blog carnivals The 16th edition of Mendel's Garden was published today for you to read and enjoy. Read the comments on this post... (Source: Living the Scientific Life (Scientist, Interrupted)) Living the Scientific Life (Scientist, Interrupted) blogs http://www.medworm.com/rss/comments.php?id=720430 Sun, 08 Jul 2007 23:52:35 +0100 720430 http://www.medworm.com/index.php?rid=418345&cid=t_175863_86_f&fid=34466&url=http%3A%2F%2Fclinicalevidence.blogspot.com%2F2007%2F02%2Fanimation-of-dna-wrapping-and.html "Molecular visualizations of DNA" is a 2003 video illustrating DNA wrapping and replication, credited to the Walter and Eliza Hall Institute of Medical Research, Howard Hughes Medical Institute, and the Dolan DNA Learning Center -- great animations and narration of both processes (found via Nobel Intent). (Source: Clinical Evidence, Searching Tidbits, and Other Minutiae) Clinical Evidence, Searching Tidbits, and Other Minutiae blogs http://www.medworm.com/rss/comments.php?id=418345 Fri, 16 Feb 2007 17:57:00 +0100 418345