MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'drug therapy'. Sat, 03 Sep 2011 02:30:56 +0100 http://www.medworm.com/index.php?rid=5077690&cid=t_135871_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fthe-best-time-to-be-treated-for-a-dvt%2F2011.07.28 You know I am a cancer survivor – 15 years down the road from a leukemia diagnosis and enjoying a 10 year remission. So whenever something seems weird about my health it’s cancer coming back, right? Wrong! Just how wrong was proven last night. I am writing this from my hospital bed in Seattle. The first symptom of a possible problem came three days ago when I had soreness in my right calf. A pulled muscle? Maybe. But I had not noticed straining it. Back at the gym the next day I had soreness again but thought it was no big deal. Last night it was worse. It hurt some to walk. I got home and, after my wife and son were asleep, got ready for bed. I had a slight fever and then noticed the right calf was not only sore, but swollen and warm. Very strange. I’d never seen that before. Trying... Better Health blogs http://www.medworm.com/rss/comments.php?id=5077690 Thu, 28 Jul 2011 18:00:02 +0100 5077690 http://www.medworm.com/index.php?rid=4758709&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2011%2F04%2F27%2Fjournal-of-the-american-medical-association-2011-vol-305-no-5%2F The objective of this study is to perform a systematic review and meta-analysis of published randomised controlled trials (RCTs) to determine the overall risk of fatal adverse effects (FAEs) associated with bevacizumab, an angiogenesis inhibitor, used in conjunction with chemotherapy. The article concludes that in a meta-analysis of RCTs, bevacizumab in combination with chemotherapy or biological therapy, compared with chemotherapy alone, was associated with increased treatment-related mortality. An NHS Athens password is required to access this article online, alternatively contact the Library for a copy of this article Filed under: Athens Password, Current Awareness, E-Journals, Journals Tagged: Bevacizumab, Cancer, Drug Therapy, Fatal Adverse Effects, Randomised Controlled Trials (Sourc... Fade Library blogs http://www.medworm.com/rss/comments.php?id=4758709 Wed, 27 Apr 2011 10:26:16 +0100 4758709 http://www.medworm.com/index.php?rid=4592397&cid=t_135871_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Ftalk-is-cheap-unless-its-talk-therapy%2F2011.03.14 Gardiner Harris had a [recent] article in the New York Times called “Talk Doesn’t Pay So Psychiatrists Turn to Drug Therapy.” The article is a twist on an old Shrink Rap topic, “Why your Shrink Doesn’t Take Your Insurance.” Only in this article the shrink does take your insurance, he just doesn’t talk to you. With his life and second marriage falling apart, a man said he needed help. But the psychiatrist, Dr. Donald Levin, stopped him and said: “Hold it. I’m not your therapist. I could adjust your medications, but I don’t think that’s appropriate.” Dr. Levin sees 40 patients a day. And he’ss 68 years old. This guy is amazing. There’s no way I could see 40 patients a day for even one day. He’s worried about his retireme... Better Health blogs http://www.medworm.com/rss/comments.php?id=4592397 Mon, 14 Mar 2011 21:00:00 +0100 4592397 http://www.medworm.com/index.php?rid=4554651&cid=t_135871_109_f&fid=34750&url=http%3A%2F%2Fpsychcentral.com%2Fblog%2Farchives%2F2011%2F03%2F06%2Fpsychiatry-doesnt-do-psychotherapy-anymore%2F Despite a trend that started as early as the late 1980s, Gardiner Harris writing in The New York Times yesterday seems to bemoan the fact that most psychiatrists don’t practice psychotherapy any longer. Perhaps Harris should have interviewed Dr. Danny Carlat, who nearly a year ago wrote about his experiences as a modern psychiatrist (in the The New York Times Magazine, no less). Psychiatrists nowadays are generally poorly trained in psychotherapy, so they spend most of their time prescribing psychiatric medications. (Dr. Carlat’s book, Unhinged is well worth the read for further background about modern psychiatry.) So I wasn’t sure why I was reading this in the “Money and Policy” section of the Times. Surely it’s not news that psychiatry is no longer pra... World of Psychology blogs http://www.medworm.com/rss/comments.php?id=4554651 Sun, 06 Mar 2011 17:16:39 +0100 4554651 http://www.medworm.com/index.php?rid=4411481&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2011%2F01%2F28%2Fnursing-times-2010-vol-107-no-3%2F This article comprises of a short briefing on safe and effective care for patients on anticoagulant therapy. Contact the Library for a copy of this article Filed under: Journals Tagged: Anticoagulant Therapy, Cardiac Thromboembolism, Deep Vein Thrombosis, Drug Therapy, Pulmonary Embolism, Thrombophilia, Venous Thromboembolism (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=4411481 Fri, 28 Jan 2011 13:57:57 +0100 4411481 http://www.medworm.com/index.php?rid=4119219&cid=t_135871_113_f&fid=39278&url=http%3A%2F%2Fblogsite.mdbuyline.com%2F%3Fp%3D73 Asthma, a chronic disease, affects over 23 million Americans and causes over 444,000 hospitalizations and 3,447 deaths per year.  But now, bronchial thermoplasty is being developed as an exciting new non-drug therapy for severe asthma.   Bronchial thermoplasty is a recently-approved outpatient procedure that consists of a single-use catheter and RF controller delivered with a bronchoscope.  The treatment uses RF energy to reduce the airway’s smooth muscle tissue from the lining, thus, decreasing the ability of the airway’s smooth muscles to constrict.  I spoke with Dr. Alan Leff, MD, an authority on asthma treatments, and he explained, “Generally, treatment options for severe asthma are not too good. Although there are currently more convenient pharmaceuticals available for les... MD Buyline blogs http://www.medworm.com/rss/comments.php?id=4119219 Wed, 27 Oct 2010 14:31:09 +0100 4119219 http://www.medworm.com/index.php?rid=3635691&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F06%2F07%2Fimplementing-value-based-pricing-for-pharmaceuticals-in-the-uk%2F Title: Implementing value-based pricing for pharmaceuticals in the UK Skinny: Report from the 2020 Health think tank explores both the opportunities and limitations of ‘value-based pricing’ (VBP) as applied to innovative medicines pricing, and seeks to identify the barriers to be overcome if it is to be introduced in ways which genuinely enhance the UK’s overall approach to patented medicines pricing and spending. Publisher: 2020 Health Size of Publication: 69p. Published: March 2010 Filed under: Financial Management, Grey Literature, Health Economics, NHS, Pharmaceutical Industry Tagged: Drug Therapy, Financial Management, Grey Literature, Health Economics, NHS, Pharmaceutical Industry, Value-Based Pricing (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3635691 Mon, 07 Jun 2010 13:09:24 +0100 3635691 http://www.medworm.com/index.php?rid=3635695&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F06%2F07%2Fheart-2010-vol-96-no-9%2F Contents page Fade Fave: Advances in antiplatelet treatment for acute coronary syndromes Fade Skinny: Recent publications of TRITON-TIMI (prasugrel) as well as PLATO (ticagrelor) have introduced new and potent antiplatelet agents, but at the same time have left clinicians with multiple choices without clear directions regarding the most appropriate use of these agents. Finds both prasugrel and ticagrelor are potent antiplatelet agents with improved ischaemic benefits in comparison with clopidogrel. The improved benefit, however, comes at the price of increased bleeding. As such, careful patient selection and balancing of benefit-risk is warranted to optimise their use in clinical practice. (NHS Athens is required to access this article online) Filed under: Athens Password, Current Awarene... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3635695 Mon, 07 Jun 2010 09:50:59 +0100 3635695 http://www.medworm.com/index.php?rid=3635699&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F06%2F07%2Fheart-2010-vol-96-no-8%2F Heart 2010 (Vol. 96 No. 8) Contents page Fade Fave: The effect of optimal medical therapy on 1-year mortality after acute myocardial infarction Fade Skinny: Assesses whether the benefits of combining spirin, β-blockers, statins, renin angiotensin system (RAS) blockers and thienopyridines (termed optimal medical therapy, OMT), will result in a reduction of mortality in clinical practice. Finds that OMT over 1 year was associated with a significantly lower mortality of patients with acute myocardial infarction in clinical practice. However OMT is provided to less than half of eligible patients leaving room for substantial improvement. (NHS Athens is required to access this article online) Filed under: Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Current Awarene... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3635699 Mon, 07 Jun 2010 09:27:28 +0100 3635699 http://www.medworm.com/index.php?rid=3197567&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F01%2F22%2Fthe-lancet-2009-volume-375-issue-9711%2F Contents Page Fade Fave: Gout Fade Skinny: Seminar on gout, a common arthritis caused by deposition of monosodium urate crystals within joints after chronic hyperuricaemia. It affects 1—2% of adults in developed countries, where it is the most common inflammatory arthritis in men. Diet and genetic polymorphisms of renal transporters of urate seem to be the main causal factors of primary gout. Gout and hyperuricaemia are associated with hypertension, diabetes mellitus, metabolic syndrome, and renal and cardiovascular diseases. Non-steroidal anti-inflammatory drugs and colchicine remain the most widely recommended drugs for treatment of acute attacks. Oral corticosteroids could be an alternative. Patient education, appropriate lifestyle advice, and treatment of comorbidities are an import... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3197567 Fri, 22 Jan 2010 09:55:49 +0100 3197567 http://www.medworm.com/index.php?rid=3182151&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F01%2F17%2Fjournal-of-the-american-medical-association-2010-vol-303-no-2%2F This article examines whether injecting platlet-rich plasma (PRP) would improve outcome in chronic midportion Achilles tendinopathy. An NHS Athens password is required to access this article online. Posted in Current Awareness, Journals Tagged: Achilles Tendinopathy, Drug Therapy (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3182151 Sun, 17 Jan 2010 18:38:51 +0100 3182151 http://www.medworm.com/index.php?rid=3182152&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F01%2F17%2Fjournal-of-the-american-medical-association-2010-vol-303-no-1%2F This article aims to explore whether antidepressant medications have a specific pharmacological effect relative to pill placebo for patients with less severe depression. The objective of this research is to estimate the relative benefit of medication vs placebo across a wide range of initial symptom severity in patients diagnosed with depression. An NHS Athens password is required to access this article online. Posted in Current Awareness, Journals Tagged: Antidepressants, Depression, Drug Therapy, Placebo (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3182152 Sun, 17 Jan 2010 18:22:35 +0100 3182152 http://www.medworm.com/index.php?rid=3167059&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F01%2F13%2Farchives-of-internal-medicine-2009-vol-170-no-1%2F contents page Fade Fave: Improving Prescription Drug Warnings to Promote Patient Comprehension Fade Skinny: Evaluates whether the use of “enhanced print” drug warnings could improve patient comprehension beyond a current standard. It finds simple, explicit language on warning labels can increase patient understanding; the addition of appropriate icons is particularly useful for adults with lower literacy skills. Evidence-based standards are needed to promote patient-centered prescription labeling practices. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Current Awareness, Drug Therapy, E-Journals, Patient Information (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3167059 Wed, 13 Jan 2010 10:55:58 +0100 3167059 http://www.medworm.com/index.php?rid=3145922&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F01%2F06%2Fnhs-european-office-policy-priorities-2010%2F Title: NHS European Office: policy priorities 2010 The Skinny: Identifies the following priorities for the NHS European Office in monitoring and disseminating information about risks arising from EU regulation in the following areas. Patient mobility Research and Innovation Competition and Public Procurement Employment Quality and Safety of Health Care Pharmaceuticals and Medical Devices Environment Commercial Transactions Publisher: NHS Confederation Size of Publication: 2p Published: 05/01/2010 Posted in Grey Literature, Legislation, NHS, Public Sector, Quality Tagged: Commercial Transactions, Commissioning, Competition, Drug Therapy, Employment, Environment, European Union, Grey Literature, Health and Safety, Horizon Scanning, Innovation, Legislation, Medical Technology, Patient Mobil... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3145922 Wed, 06 Jan 2010 13:50:17 +0100 3145922 http://www.medworm.com/index.php?rid=3111365&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F22%2Fjournal-of-the-american-medical-association-2009-vol-302-no-23%2F The objective of this study is to determine the efficacy, safety, and tolerabilityof tarenflurbil. An NHS password is needed to access this journal online. A print copy if available from the library. Posted in Current Awareness, Journals Tagged: Alzheimers Disease, Drug Therapy, Research (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3111365 Tue, 22 Dec 2009 13:57:33 +0100 3111365 http://www.medworm.com/index.php?rid=3111366&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F22%2Fjournal-of-clinical-pathology-2009-vol-62-no-12%2F contents page Fade Fave: Drug-related cardiac pathology Fade Skinny: Discusses drug-related cardiotoxic effects of antineoplastic agents, psychotropic medications, heavy metals, substances of abuse, promotility agents, antihistamines, antimicrobials, antiarrhythmic agents and hypersensitivity myocarditis. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Current Awareness, Drug Therapy, E-Journals, Pathology, Toxicity (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3111366 Tue, 22 Dec 2009 13:52:19 +0100 3111366 http://www.medworm.com/index.php?rid=3089222&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F14%2Farchives-of-internal-medicine-2009-vol-169-no-21%2F contents page Fade Fave: Meta-analysis of the Impact of 9 Medication Classes on Falls in Elderly Persons Fade Skinny: Identifies an increasing recognition that the use of certain medications contributes to falls in seniors. Updates a previously completed meta-analysis looking at the association of medication use and falling to include relevant drug classes and new studies that have been completed since a previous meta-analysis. Finds the use of sedatives and hypnotics, antidepressants, and benzodiazepines demonstrated a significant association with falls in elderly individuals. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Current Awareness, Drug Therapy, E-Journals, Falls, Older People (Source: Fa... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3089222 Mon, 14 Dec 2009 20:30:40 +0100 3089222 http://www.medworm.com/index.php?rid=3084717&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F14%2Fdosage-of-oseltamivir-in-children-under-6-months-of-age-in-the-swine-flu-pandemic%2F Title: Dosage of oseltamivir in children under 6 months of age in the swine flu pandemic Skinny: Provides information about changes to the dose of oseltamivir in children under 6 months of age during an influenza pandemic outbreak and the steps that need to be taken to ensure a safe transition to the new dosage. Publisher: DH Size of Publication: 5p. Published: 19/11/2009 Posted in Grey Literature, Infants, Influenza, Pandemic, Prescribing Tagged: Drug Therapy, Grey Literature, H1N1, Infants, Influenza, Pandemic (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3084717 Mon, 14 Dec 2009 14:30:04 +0100 3084717 http://www.medworm.com/index.php?rid=3084720&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F14%2Fauthorisation-of-antiviral-medicines-guidance-on-the-use-of-fp10ss-forms-and-antiviral-authorisation-vouchers-during-the-h1n1-swine-flu-pandemic-in-england-2%2F Title: Authorisation of antiviral medicines – Guidance on the use of FP10SS forms and Antiviral Authorisation Vouchers during the H1N1 (swine flu) pandemic in England Skinny: Updated guidance to inform the NHS about the new Antiviral Authorisation Vouchers for children under 1 year of age issued in November 2009. This follows the European Commission decision to accept the advice of the European Medicines Evaluation Agency to change the recommended dose of Tamiflu for children under 6 months of age during an influenza pandemic outbreak. These Antiviral Authorisation Vouchers include the new dosage regimen for oseltamivir  and will ensure that children under one year of age get the recommended dose for their age and weight. Publisher: DH Size of Publication:28p. Published: 20/11/2009 ... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3084720 Mon, 14 Dec 2009 12:30:54 +0100 3084720 http://www.medworm.com/index.php?rid=3084730&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F14%2Fheart-2009-vol-95-no-23%2F Contents page Fade Fave: Psychotropic medication use and risk of adverse cardiovascular events in women with suspected coronary artery disease: outcomes from the Women’s Ischemia Syndrome Evaluation (WISE) study Fade Skinny: Investigates the relation between psychotropic medication use and adverse cardiovascular (CV) events in women with symptoms of myocardial ischaemia undergoing coronary angiography. Finds that factors related to psychotropic medication such as depression refractory to treatment, or medication use itself, are associated with adverse CV events in women with suspected myocardial ischaemia. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Current Awareness, Drug Therapy, E-Journals, H... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3084730 Mon, 14 Dec 2009 09:30:46 +0100 3084730 http://www.medworm.com/index.php?rid=3044685&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F01%2Fgovernment-response-to-professor-sube-banerjee%25e2%2580%2599s-report-on-the-prescribing-of-anti-psychotic-drugs-to-people-with-dementia%2F Title: Government response to Professor Sube Banerjee’s report on the prescribing of anti-psychotic drugs to people with dementia Skinny: Government response to Professor Sube Bannerjee’s independent clinical review of the use of anti-psychotic drugs.  This was conducted in recognition of widespread concern about the over-prescription of anti-psychotic drugs, and as part of the priority being given to improving care for people with dementia. Publisher: DH Size of Publication: 2p. Published: 12/11/2009 Posted in Alzheimers Disease, Dementia, Grey Literature, NHS Tagged: Alzheimers Disease, Anti-Psychotics, Dementia, Drug Therapy, Ethics, Grey Literature (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3044685 Tue, 01 Dec 2009 08:40:20 +0100 3044685 http://www.medworm.com/index.php?rid=3044686&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F01%2Fthe-use-of-antipsychotic-medication-for-people-with-dementia-time-for-action-a-report-for-the-minister-of-state-for-care-services%2F Title: The use of antipsychotic medication for people with dementia: Time for action. A report for the Minister of State for Care Services Skinny: Clinical review of the use of anti-psychotic drugs conducted in recognition of widespread concern about the over-prescription of anti-psychotic drugs, and as part of the priority being given to improving care for people with dementia. Publisher: DH Size of Publication: 63p. Published: 12/11/2009 Posted in Alzheimers Disease, Dementia, Grey Literature, Older People Tagged: Alzheimers Disease, Anti-Psychotics, Drug Therapy, Ethics, Grey Literature (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3044686 Tue, 01 Dec 2009 08:35:36 +0100 3044686 http://www.medworm.com/index.php?rid=3039736&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F11%2F30%2Fconsultation-on-proposals-for-the-innovation-pass-pilot%2F Title: Consultation on proposals for the Innovation Pass pilot Skinny: Seeks views from the NHS, industry and other stakeholders on the Government’s proposals for an Innovation Pass pilot.  These proposals will be revised in light of comments received as part of this consultation and will be used to inform the first set of decisions for the pilot in 2010/1.  The Innovation Pass will make selected innovative medicines available on the NHS for a time-limited period, prior to a NICE appraisal.  Funding will be drawn from a new ring-fenced £25m budget, set aside exclusively for the Innovation Pass. The Pass gives earlier access to innovative drugs for patients with the greatest need, and at the same time it will facilitate the collection of further information to support a subsequent NIC... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3039736 Mon, 30 Nov 2009 14:46:16 +0100 3039736 http://www.medworm.com/index.php?rid=2993725&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F11%2F15%2Fbristol-myers-squibb-pharmaceuticals-ltd-r-on-the-application-of-v-national-institute-for-health-and-clinical-excellence-2009%2F Title: Bristol-Myers Squibb Pharmaceuticals Ltd, R (on the application of) v National Institute for Health and Clinical Excellence [2009] The Skinny: Challenges of the decision of the defendant, the National Institute for Health and Clinical Excellence (NICE) refusing to recommend the use of abatacept (ABA) for treatment in connection with rheumatoid arthritis in the National Health Service in the United Kingdom. Publisher: Bailii Size of Document: Webpage Case No.:EWHC 2780 (Admin) (06 November 2009) Posted in Jurisprudence Tagged: Arthiritis, Cost Effectiveness, Drug Therapy, Evidence Based Practice, Jurisprudence (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2993725 Sun, 15 Nov 2009 12:11:20 +0100 2993725 http://www.medworm.com/index.php?rid=2989101&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F11%2F13%2Fthe-lancet-2009-volume-374-issue-9702%2F Contents Page Fade Fave: 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study Fade Skinny: In the 2·8 years of the Diabetes Prevention Program (DPP) randomised clinical trial, diabetes incidence in high-risk adults was reduced by 58% with intensive lifestyle intervention and by 31% with metformin, compared with placebo. This 10 year follow-up finds that incidences in the former placebo and metformin groups fell to equal those in the former lifestyle group, but the cumulative incidence of diabetes remained lowest in the lifestyle group. Prevention or delay of diabetes with lifestyle intervention or metformin can persist for at least 10 years. (Print Subscription Held by the Fade Library) Posted in Current Awareness, Journals Tagged: Cur... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2989101 Fri, 13 Nov 2009 12:08:47 +0100 2989101 http://www.medworm.com/index.php?rid=2930908&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F10%2F27%2Fmanaging-patients%25e2%2580%2599-medicines-after-discharge-from-hospital%2F Title: Managing patients’ medicines after discharge from hospital Skinny: Report that raises concerns that : GPs and hospitals do not always exchange enough information about medicines, and don’t share it on time. In a minority of GP practices (17%), administrative staff rather than clinical staff update records, and they don’t have the clinical skills to check whether medications are right. There’s not enough being done to talk to patients themselves about their medications, either when they’re discharged from hospital or in the longer term. Monitoring and learning from serious incidents is patchy. Publisher: Care Quality Commission Size of Publication: 56p Published: 27/10/2009 Tool: Managing patients’ medicine after discharge – self-assessment tool North West Report: Stu... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2930908 Tue, 27 Oct 2009 13:00:00 +0100 2930908 http://www.medworm.com/index.php?rid=2842445&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F09%2F29%2Fpandemic-influenza-recommendations-on-the-use-of-antiviral-medicines-for-pregnant-women-women-who-are-breastfeeding-and-children-under-the-age-of-one-year%2F Title: Pandemic influenza guidance on pregnancy, breastfeeding and children under the age of one The Skinny: Supplemental to the Department of Health guidance:  Pandemic influenza: guidance on preparing maternity services. It reinforces and clarifies the advice in the main guidance, and provides advice for the use of antiviral medicines in women who are breastfeeding. It also gives details of the safety and efficacy of these medicines. This document has been updated in September 2009 with new information on: the dose of oseltamivir for children aged 6 months and over and up to one year of age and treatment of pregnant women Publisher: DH Size of Publication: 6p Published: 29/09/2009 Posted in Grey Literature, Infants, Influenza, NHS, Pandemic Tagged: Breastfeeding, Drug Therapy, Grey Li... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2842445 Tue, 29 Sep 2009 18:37:18 +0100 2842445 http://www.medworm.com/index.php?rid=2842447&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F09%2F29%2Fauthorisation-of-antiviral-medicines-guidance-on-the-use-of-fp10ss-forms-and-antiviral-authorisation-vouchers-during-the-h1n1-swine-flu-pandemic-in-england%2F Title: Authorisation of antiviral medicines – Guidance on the use of FP10SS forms and Antiviral Authorisation Vouchers during the H1N1 (swine flu) pandemic in England The Skinny: New guidance document on the use of Antiviral Authorisation Vouchers. This guidance has been issued for two reasons: authorisation of antiviral medicines using Antiviral Authorisation Vouchers as well as specifically endorsed FP10SS forms has now been enabled. a change in the recommended dose for oseltamivir for children 6 months and over and up to 1 year of age from 2mg/kg to 3mg/kg has been announced by the European Commission. This guidance contains useful information on: when Antiviral Authorisation Vouchers / FP10SS forms can be used to authorise antiviral medicines, how Antiviral Authorisation Vouch... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2842447 Tue, 29 Sep 2009 17:12:08 +0100 2842447 http://www.medworm.com/index.php?rid=2751834&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F09%2F01%2Fheart-2009-vol-95-no-18%2F Contents page Fade Fave: Therapeutic strategies after coronary stenting in chronically anticoagulated patients: the MUSICA study Fade Skinny:Finds that in patients receiving oral anticoagulant therapy (OAT), triple therapy (TT) was the most commonly used regimen after stenting percutaneous coronary intervention and stent implantation (PCI-S). Double antiplatelet therapy (DAT) was associated with the lowest rate of bleeding events and a similar efficacy to TT in patients at low thromboembolic risk. TT should probably be restricted to patients at moderate–high thromboembolic risk. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals, Heart Diseases Tagged: Athens Password, Coronary Stents, Current Awareness, Drug Therapy, E-Journa... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2751834 Tue, 01 Sep 2009 13:25:35 +0100 2751834 http://www.medworm.com/index.php?rid=2751835&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F09%2F01%2Fthe-lancet-2009-volume-374-issue-9691%2F Contents Page Fade Fave:Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials Fade Skinny:The phosphodiesterase-4 inhibitor roflumilast can improve lung function and prevent exacerbations in certain patients with chronic obstructive pulmonary disease (COPD). Investigates whether roflumilast would reduce the frequency of exacerbations requiring corticosteroids in patients with COPD.  Finds that since different subsets of patients exist within the broad spectrum of COPD, targeted specific therapies could improve disease management. (Print Subscription Held by the Fade Library) Posted in Current Awareness, Journals Tagged: COPD, Current Awareness, Drug Therapy, Journals (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2751835 Tue, 01 Sep 2009 12:19:56 +0100 2751835 http://www.medworm.com/index.php?rid=2751840&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F09%2F01%2Fthe-safer-management-of-controlled-drugs-annual-report-2008%2F Title: The safer management of controlled drugs – Annual report 2008 The Skinny: Details significant progress in implementing regulations introduced in response to the Shipman Inquiry, to monitor controlled drugs but finds there are still important parts of the system that need to be improved. Publisher: Care Quality Commission Size of Publication: 76p Published: 27/08/2009 Posted in Grey Literature, NHS, Pharmacy, Quality Tagged: Drug Therapy, Grey Literature, Health and Safety, Management, NHS, Pharmacy, Quality (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2751840 Tue, 01 Sep 2009 11:28:19 +0100 2751840 http://www.medworm.com/index.php?rid=2724797&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F08%2F21%2Fchemotherapy-services-in-england-ensuring-quality-and-safety%2F Title: Chemotherapy Services in England: Ensuring quality and safety The Skinny: Final report from the National Chemotherapy Advisory Group takes account of the responses received during the consultation period.  It aims to improve the quality and safety of chemotherapy services for adult patients with either solid cancers or haematological malignancies and many of the recommendations are applicable in the care of children and young people. Highlights the need to improve both elective chemotherapy services and acute oncology services. Publisher: DH Size of Publication: 71p Published: 21/08/2009 Posted in Adults, Cancer, Grey Literature, NHS, Quality Tagged: Cancer, Drug Therapy, Grey Literature, NHS, Quality (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2724797 Fri, 21 Aug 2009 13:43:00 +0100 2724797 http://www.medworm.com/index.php?rid=2709079&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F08%2F18%2Fthe-lancet-2009-volume-374-issue-9689%2F Contents Page Fade Fave:Antithrombotic management of patients with prosthetic heart valves: current evidence and future trends Fade Skinny:Reviews antithrombotic therapies for patients with prosthetic heart valves and management of thromboembolic complications. Advances in antithrombotic therapy and valve technologies are likely to improve the management of patients with prosthetic heart valves in developed countries, identifies unmet need and potential for benefit from these new therapies is in developing countries. (Print Subscription Held by the Fade Library) Posted in Current Awareness Tagged: Current Awareness, Drug Therapy, Heart Diseases, Journals, Prostethics, Surgery (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2709079 Tue, 18 Aug 2009 10:03:39 +0100 2709079 http://www.medworm.com/index.php?rid=2610869&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F07%2F16%2Fannals-of-rheumatic-diseases-2009-volume-68-no-8%2F Contents Page Title: Opportunities for improving medication use and monitoring in gout Fade Skinny: Finds variations in patterns of medication use and monitoring in patients with gout with suboptimal care. A concerted effort is needed to improve the overall care of gout. (Requires NHS Athens Password for Access) Posted in Access from Home, Access from Work, Access in the Library, Athens Password, Current Awareness, E-Journals, Electronic Resources Tagged: Athens Password, Current Awareness, Drug Therapy, E-Journals, Gout (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2610869 Thu, 16 Jul 2009 13:09:06 +0100 2610869 http://www.medworm.com/index.php?rid=2404961&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F05%2F13%2Ffungal-nail-infection-onychomycosis-%25e2%2580%2593-management%2F Title: Fungal nail infection (onychomycosis) – Management Source: Clinical Knowledge Summaries The Skinny: Details diagnosis, treatment and patient advice in relation to fungal nail infection. Date of publication: May 2009 Publication type: Clinical Knowledge Summary Acknowledgement: http://cks.library.nhs.uk Posted in Clinical Knowledge Summary Tagged: Diagnosis, Drug Therapy, Mycoses, Nails, Patient Information, Self Care (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2404961 Wed, 13 May 2009 08:37:04 +0100 2404961 http://www.medworm.com/index.php?rid=2404962&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F05%2F13%2Ffungal-skin-infection-%25e2%2580%2593-body-and-groin-%25e2%2580%2593-management%2F Title: Fungal skin infection – body and groin – Management Source: Clinical Knowledge Summaries The Skinny: Fungal infection of the skin is caused by dermatophytes, and is also known as ringworm or tinea, this summary covers diagnosis, investigations,  advice, treatment and referral for instances on the body and groin. Date of publication: May 2009 Publication type: Clinical Knowledge Summary Acknowledgement: http://cks.library.nhs.uk Posted in Clinical Knowledge Summary Tagged: Diagnosis, Drug Therapy, Mycoses, Nails, Patient Information, Self Care (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2404962 Wed, 13 May 2009 08:31:22 +0100 2404962 http://www.medworm.com/index.php?rid=2404963&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F05%2F13%2Ffungal-skin-infection-%25e2%2580%2593-foot-%25e2%2580%2593-management%2F Title: Fungal skin infection – foot – Management Source: Clinical Knowledge Summaries The Skinny: Fungal infection of the foot (athlete’s foot or tinea pedis) is a superficial skin infection of the feet and toes, predominantly caused by dermatophytes, this summary covers diagnosis, investigations,  advice, treatment and referral for instances on the body and groin. Date of publication: May 2009 Publication type: Clinical Knowledge Summary Acknowledgement: http://cks.library.nhs.uk Posted in Clinical Knowledge Summary Tagged: Diagnosis, Drug Therapy, Mycoses, Nails, Patient Information, Self Care (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2404963 Wed, 13 May 2009 08:29:02 +0100 2404963 http://www.medworm.com/index.php?rid=2404965&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F05%2F13%2Fgiant-cell-arteritis-%25e2%2580%2593-management%2F Title: Giant cell arteritis – Management Source: Clinical Knowledge Summaries The Skinny: Giant Cell Ateritis is a systemic inflammatory vasculitis of unknown etiology that affects medium- and large-sized arteries . It is a disease of elderly persons and can result in a wide variety of systemic, neurologic, and ophthalmologic complications. Visual loss is one of the most significant causes of morbidity in GCA. Permanent visual impairment may occur in as many as 60% of patients. This summary details initial management, the need for shared care, treatment and advice and information for the patient. Date of publication: May 2009 Publication type: Clinical Knowledge Summary Acknowledgement: http://cks.library.nhs.uk Posted in Clinical Knowledge Summary Tagged: Drug Therapy, OphthalmologySha... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2404965 Wed, 13 May 2009 07:20:40 +0100 2404965 http://www.medworm.com/index.php?rid=2404966&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F05%2F13%2Fpolymyalgia-rheumatica-%25e2%2580%2593-management%2F Title: Polymyalgia rheumatica – Management Source: Clinical Knowledge Summaries The Skinny: Polymyalgia rheumatica (PMR) is a condition which causes inflammation of large muscles. It mainly affects people over the age of 65. It is rare in people under 60. About 4 in 10,000 people over the age of 60 develop PMR each year. Women are three times more likely to be affected than men. This summary contains details of initial and ongoing management, referral and patient information and advice. Date of publication: May 2009 Publication type: Clinical Knowledge Summary Acknowledgement: http://cks.library.nhs.uk Posted in Ooops Missed Category! Tagged: Drug Therapy, Muscles, Muscular Diseases, Older People, Pain, Prescriptions (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2404966 Wed, 13 May 2009 07:19:17 +0100 2404966 http://www.medworm.com/index.php?rid=2367339&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F25%2Frivaroxaban-for-the-prevention-of-venous-thromboembolism%2F Title: Rivaroxaban for the prevention of venous thromboembolism Source: NICE The Skinny: This guidance is about when rivaroxaban should be used to reduce the risk of thromboembolism in adults who have surgery to replace their hip or knee joints in the NHS in England and Wales. It explains guidance (advice) from NICE (the National Institute for Health and Clinical Excellence). It does not cover using rivaroxaban to reduce the risk of venous thromboembolism in adults who have had other types of surgery. Documents For healthcare professionals: TA170 Venous thromboembolism - rivaroxaban: guidance (23p, 190.93 Kb) TA170 Venous thromboembolism - rivaroxaban: guidance (MS Word format) (23p, 553.5 Kb) TA170 Venous thromboembolism - rivaroxaban: quick ref guide(2p, 42.73 Kb) Documents For patient... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367339 Sat, 25 Apr 2009 05:57:47 +0100 2367339 http://www.medworm.com/index.php?rid=2367347&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2F100%2F Title: Rheumatoid arthritis: the management of rheumatoid arthritis in adults Source: NICE The Skinny:Rheumatoid arthritis is a long-term disease in which joints in the body become inflamed, causing pain, swelling and stiffness. It is known as an ‘autoimmune disease’ because it is caused when the body’s immune system, which normally fights infection, starts to attack healthy joints. Rheumatoid arthritis can be very painful and affect a person’s ability to carry out everyday tasks. It is not known why rheumatoid arthritis develops, and there is no cure. Understanding of the disease has improved, and there are now effective treatments that can help ease the pain and symptoms, and slow down the disease. It is very important that treatment is started early to minimise d... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367347 Wed, 15 Apr 2009 09:41:31 +0100 2367347 http://www.medworm.com/index.php?rid=2367352&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2Fcore-interventions-in-the-treatment-and-management-of-schizophrenia-in-primary-and-secondary-care-update%2F Title: Core interventions in the treatment and management of schizophrenia in primary and secondary care (update) Source: NICE The Skinny: Updates and replaces: Schizophrenia: core interventions in the treatment and management of schizophrenia in primary and secondary care. NICE clinical guideline 1 (2002) Guidance on the use of newer (atypical) antipsychotic drugs for the treatment of schizophrenia. NICE technology appraisal guidance 43 (2002) Documents For healthcare professionals: CG82 Schizophrenia (update): NICE guideline (41p, 256.26 Kb) CG82 Schizophrenia (update): NICE guideline (MS Word format) (41p, 605 Kb) CG82 Schizophrenia (update): full guideline (399p, 3.16 Mb) CG82 Schizophrenia (update): full guideline - clinical evidence summary tables (194p, 2.54 Mb) CG82 Schizophren... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367352 Wed, 15 Apr 2009 09:38:28 +0100 2367352 http://www.medworm.com/index.php?rid=2367355&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2Fearly-and-locally-advanced-breast-cancer-diagnosis-and-treatment%2F Title: Early and locally advanced breast cancer: diagnosis and treatment Source: NICE The Skinny: This guideline covers: some of the tests and treatments that patients with early and locally advanced breast cancer should be offered, in particular: – reducing the amount of surgery under your arm – breast reconstruction when breast conservation is not possible – chemotherapy and endocrine treatments – biological treatments. It does not specifically look at: the care of patients with advanced breast cancer or those with rare or non-cancerous tumours of the breast the care of people who do not have breast cancer themselves but have a family history of the disease. This guideline updates the following technology appraisals: TA107 Breast cancer (early) - trastuzumab (published Augu... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367355 Wed, 15 Apr 2009 09:38:01 +0100 2367355 http://www.medworm.com/index.php?rid=2367358&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2Fmedicines-adherence-involving-patients-in-decisions-about-prescribed-medicines-and-supporting-adherence%2F Title: Medicines adherence: involving patients in decisions about prescribed medicines and supporting adherence Source: NICE The Skinny:  Guidance about enabling patients to make informed choices by involving and supporting them in decisions about prescribed medicines. It explains guidance (advice) from NICE (the National Institute for Health and Clinical Excellence) to the NHS in England and Wales. Documents For healthcare professionals: CG76 Medicines adherence: NICE guideline (30p, 204.99) CG76 Medicines adherence: NICE guideline (MS Word format) (30p, 659.5 Kb) CG76 Medicines adherence: full guideline (364p, 1.27 Mb) CG76 Medicines adherence: quick reference guide (12p, 348.46 Kb) CG76 Medicines adherence: full guideline, appendix A (9p, 100.32 Kb) CG76 Medicines adherence: full guid... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367358 Wed, 15 Apr 2009 09:35:42 +0100 2367358 http://www.medworm.com/index.php?rid=2367360&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2Fadvanced-breast-cancer-diagnosis-and-treatment%2F Title: Advanced breast cancer: diagnosis and treatment Source: NICE The Skinny: Updates and replaces NICE technology appraisal guidance 62 (published May 2003), 54 (published December 2002) and 30 (published September 2001). The advice in the NICE guideline describes the tests, treatment, care and support that patients with advanced breast cancer should be offered. It does not specifically describe the care of patients with early breast cancer or those with rare or non-cancerous tumours of the breast. Documents For healthcare professionals: CG81 Advanced breast cancer: NICE guideline (26p, 222.55 Kb) CG81 Advanced breast cancer: NICE guideline (MS Word format) (26p, 586 Kb) CG81 Advanced breast cancer: full guideline (122p, 3.03 Mb) CG81 Advanced breast cancer: quick reference guide (14p... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367360 Wed, 15 Apr 2009 09:34:41 +0100 2367360 http://www.medworm.com/index.php?rid=2367363&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2Fborderline-personality-disorder-bpd%2F Title: Borderline personality disorder: treatment and management Source: NICE The Skinny: Covers the care, treatment and support that people with borderline personality disorder should be offered. Documents For healthcare professionals: CG78 Borderline personality disorder (BPD): NICE guideline, (41p., 270.06 Kb) CG78 Borderline personality disorder (BPD): NICE guideline (MS Word format), (41p, ,642.5 Kb) CG78 Borderline personality disorder (BPD): full guideline, interim proof copy, (495p., 2.94 Mb) CG78 Borderline personality disorder (BPD): quick reference guide, (20p, 502.26 Kb) Documents For patients, carers and the public: CG78 Borderline personality disorder (BPD): understanding NICE guidance, (16p, 287.69 Kb) CG78 Borderline personality disorder (BPD): understanding NICE guid... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367363 Wed, 15 Apr 2009 09:33:31 +0100 2367363 http://www.medworm.com/index.php?rid=2367369&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2Fsunitinib-for-the-first-line-treatment-of-advanced-andor-metastatic-renal-cell-carcinoma%2F Title: Sunitinib for the first-line treatment of advanced and/or metastatic renal cell carcinoma Source: NICE The Skinny: NICE has been appraising the use of bevacizumab, sorafenib, sunitinib and temsirolimus for the treatment of advanced and/or metastatic renal cell carcinoma. Sunitinib is recommended as a possible first drug treatment for people with advanced and/or metastatic renal cell carcinoma if: immunotherapy (for example, interferon alfa) would be suitable for them and they are mobile and can do light housework or office work. When assessing people with disabilities, healthcare professionals should bear in mind that a person’s disability might also affect their level of physical activity. They should make adjustments for this. Specialists should not stop prescribing sunitinib ... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367369 Wed, 15 Apr 2009 09:32:23 +0100 2367369 http://www.medworm.com/index.php?rid=2367373&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F04%2F15%2Famantadine-oseltamivir-and-zanamivir-for-the-treatment-of-influenza-review-of-existing-guidance-no-58%2F Title: Amantadine, oseltamivir and zanamivir for the treatment of influenza (review of existing guidance No. 58) Source: NICE The Skinny: Recommendations about oseltamivir and zanamivir should not reduce efforts to give vaccination (also called the flu jab) to people for whom it is recommended in national guidelines. The guidance does not cover widespread epidemics. Oseltamivir and zanamivir are recommended as possible treatments for people with flu if all of the following apply: the person is in an ‘at-risk’ group the person has a ‘flu-like illness’ and can start treatment within 48 hours (36 hours for zanamivir treatment in children) of the first sign of symptoms. the flu virus is known to be going around and it is likely that a flulike illness has been caused by... Fade Library blogs http://www.medworm.com/rss/comments.php?id=2367373 Wed, 15 Apr 2009 09:31:54 +0100 2367373 http://www.medworm.com/index.php?rid=1990572&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F11%2F26%2Fdefinitely-not-the-fifth-largest-city-in-france-new-nice-guidelines%2F Attention deficit hyperactivity disorder (ADHD) Osteoporosis- primary prevention Osteoporosis - secondary prevention Lung cancer (non-small cell) – erlotinib Electrically-stimulated intravesical chemotherapy for superficial bladder cancer Laparoscopic prostatectomy for benign prostatic obstruction Transabdominal artificial bowel sphincter implantation for faecal incontinence Posted in Clinical Governance, Clinical Guidelines, NHS   Tagged: Bladder Cancer, Clinical Guidelines, Drug Therapy, Faecal Incontinence, Hyperactivity, Lung Cancer, Osteoporosis, Surgery    (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1990572 Wed, 26 Nov 2008 07:15:04 +0100 1990572 http://www.medworm.com/index.php?rid=1960519&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F11%2F13%2Fchemotherapy-services-in-england-ensuring-quality-and-safety-a-report-from-the-national-chemotherapy-advisory-group-draft-for-consultation%2F aims to bring about a step change in the quality and safety of chemotherapy services for adult patients with either solid cancers or haematological malignancies. The report sets out a framework for planning and monitoring services based on a care pathway model and the actions that need to be taken by commissioners and providers to ensure high quality care. Posted in Cancer, Clinical Governance, Grey Literature   Tagged: Cancer, Care Pathways, Commissioning, Drug Therapy, Grey Literature, Health and Safety, Quality, Strategic Planning    (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1960519 Thu, 13 Nov 2008 15:29:27 +0100 1960519 http://www.medworm.com/index.php?rid=1870545&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F10%2F11%2Fpolicies-and-practices-for-mental-health-in-europe%2F (Briefing Document and Fact sheet) from the World Health Organization European Regional Office provides data not hitherto available on mental health policy and practice across the European Region. It also highlights important information gaps. Policies and practices for mental health in Europe allows for country to country comparisons on indicators such as numbers of psychiatrists, financing, community services, training of workforce, prescription of anti-depressants and representation of users and carers. Data for the 42 Member States involved was obtained from ministries of health.  The report finds that Britain leads the way in Europe when it comes to mental health provision,  but there is more to do to bring it up to the standard of our physical health services Posted in Grey Litera... Fade Library blogs http://www.medworm.com/rss/comments.php?id=1870545 Sat, 11 Oct 2008 09:08:47 +0100 1870545 http://www.medworm.com/index.php?rid=1825429&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F09%2F24%2Fnice-to-meet-you-to-meet-you-latest-nice-guidance%2F Attention deficit hyperactivity disorder (ADHD) Chronic Kidney Disease Identifying and supporting people most at risk of dying prematurely Venous Thromboembolism - dabigatran Influenza (prophylaxis) - zanamivir, amantadine and oseltamivir Autologous pancreatic islet cell transplantation for improved glycaemic control after pancreatectomy Balloon catheter dilation of paranasal sinus ostia for chronic sinusitis Posted in NHS, Quality   Tagged: Clinical Guidelines, Diabetes, Drug Therapy, Hyperactivity, Influenza, Kidney Diseases, Mortality, Surgery, Thromboembolism, Transplantation Services    (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1825429 Wed, 24 Sep 2008 10:50:16 +0100 1825429 http://www.medworm.com/index.php?rid=1790190&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F09%2F13%2Ftop-up-payments-for-drugs-in-england%2F How are top-ups distinct from other charges in the NHS and why have they become such a contentious issue now? This briefing from the King’s Fund gives some background on the relevant legislation and guidance in this area.  It: describes how top-ups are distinct from other charges in the NHS and why they have become such a contentious issue now outlines the relevant legislation and guidance in this area sets out the opposing positions on top-ups You can listen speakers in the debate held at the King’s Fund on the topic here. (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1790190 Sat, 13 Sep 2008 12:26:51 +0100 1790190 http://www.medworm.com/index.php?rid=1543004&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F06%2F25%2Ftwice-as-nice-im-in-paradise-latest-nice-guidelines%2F Lumbar infusion test for the investigation of normal pressure hydrocephalus (IP) Implantation of multifocal (non-accommodative) intraocular lenses during cataract surgery (IP) Stent insertion for bleeding oesophageal varices (IP) Transcatheter aortic valve implantation for aortic stenosis (IP) Surgical repair of vaginal wall prolapse using mesh (IP) Rimonabant for the treatment of overweight and obese patients (TA) Head and neck cancer - cetuximab (TA) Psoriasis- adaliumamb (TA) (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1543004 Wed, 25 Jun 2008 06:58:39 +0100 1543004 http://www.medworm.com/index.php?rid=1537841&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F06%2F21%2Fshould-topping-up-be-allowed%2F looks at the issues surrounding whether or not patients should be able to buy additional treatments not offered by the NHS. The paper critically evaluates the current system, highlighting how the current inconsistencies must be addressed so that the NHS is not undermined. (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1537841 Sat, 21 Jun 2008 05:47:18 +0100 1537841 http://www.medworm.com/index.php?rid=1472375&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F05%2F28%2Fnicely-nicely-latest-guidance-from-nice%2F Anaemia (cancer-treatment induced) - epoetin (alfa & beta) & darbepoetin (TA) Adalimumab, etanercept and infliximab for ankylosing spondylitis Type 2 Diabetes (review) (CG) Lipid Modification (CG) Canaloplasty for primary open angle glaucoma (IP) Endoaortic balloon occlusion for cardiac surgery (IP) Single incision mid-urethral tape insertion for stress urinary incontinence in women (IP) Workplace physical activity (PH) (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1472375 Wed, 28 May 2008 11:19:59 +0100 1472375 http://www.medworm.com/index.php?rid=1451853&cid=t_135871_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F293059418%2F (Photo credit: Destiny Pharma www.destinypharma.com)  Researchers at UK’s Destiny Pharma believe they have developed a drug which can destroy the most virulent strains of MRSA.  They are testing the drug code named XF-73 in the hope it can be used in hospitals by 2011. Study results of the new drug, which is applied as a gel into patients’ noses, showed methicillin-resistant Staphylococcus aureus bacteria (MRSA) did not develop resistance to the compound despite being exposed to it 55 times. Elaine Warburton  www.geneticsandhealth.com Tags: cgenomics, drug therapy, MRSA, pharmaoShare This (Source: Genetics and Health) Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1451853 Sun, 18 May 2008 21:34:34 +0100 1451853 http://www.medworm.com/index.php?rid=1392474&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F04%2F23%2Fnice-nice-baby-latest-clinical-guidelines-from-nice%2F Allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus Intraoperative red blood cell salvage during radical prostatectomy or radical cystectomy Interstitial photodynamic therapy for malignant parotid tumours Perioperative hypothermia (inadvertent) Ulcerative colitis - infliximab Abatacept for the treatment of rheumatoid arthritis (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1392474 Wed, 23 Apr 2008 07:52:45 +0100 1392474 http://www.medworm.com/index.php?rid=1169549&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F01%2F23%2Fnot-naughty-but-nice-latest-nice-guidelines%2F Interventions in medicines reconcilliation at the point of admission Physical activity and environment Psoriasis - infliximab Ultrasound guided catheterisation of the epidural space Arteriovenous extracorporeal membrane carbon dioxide removal Mesothelioma - Pemetrexed (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1169549 Wed, 23 Jan 2008 09:25:03 +0100 1169549 http://www.medworm.com/index.php?rid=1156737&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F01%2F17%2Fprescribing-costs-in-primary-care-second-report-of-session-2007%25e2%2580%259308%2F Creating a stir in the news today is House of Commons Committee of Public Accounts (2008) Department of Health: Prescribing costs in primary care: Second Report of Session 2007–08: Report, together with formal minutes, oral and written evidence. London: TSO it concludes and recommends: The NHS could save more than £200 million a year, without affecting patient care, by GPs prescribing lower cost but equally effective medicines. Generic drugs should be prescribed The proportion of prescriptions written by chemical name rather than by brand name, known as generic prescribing, rose from 51% in April 1994 to 83% in September 2006. Where it is clinically appropriate, GPs should prescribe those available in generic form. The proportion of lower cost prescriptions for some common condit... Fade Library blogs http://www.medworm.com/rss/comments.php?id=1156737 Thu, 17 Jan 2008 09:17:05 +0100 1156737 http://www.medworm.com/index.php?rid=1140905&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F01%2F10%2Fthe-house-of-commons-health-committee-national-institute-for-health-and-clinical-excellence-first-report-of-session-2007%25e2%2580%259308-volume-i-report-together-with-formal-minutes%2F The report identifies the following problems Topic selection. Only a few selected medical technologies are chosen as suitable for assessment as technology appraisals. There is also far too little emphasis on disinvestment. Here we found NICE’s responses to our questions disingenuous. While few older treatments may do no good at all, many will not be cost-effective; The wider benefits of treatment to society, for example to carers, are not included in NICE’s economic evaluations; NICE often does not have all the information it needs to make a full assessment. It does not have access to all the information the Medicines and Healthcare products Regulatory Agency (MHRA) uses and clinical trials are usually designed without NICE’s work on cost-effectiveness in mind; Experts are no... Fade Library blogs http://www.medworm.com/rss/comments.php?id=1140905 Thu, 10 Jan 2008 09:00:42 +0100 1140905 http://www.medworm.com/index.php?rid=1128576&cid=t_135871_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F01%2F03%2Fnational-care-of-the-dying-audit%2F generic report 2006/2007 considers the care of the dying in five key areas and finds that: Physical Comfort of the Patient  Medication was assessed and non-essential medication was stopped in 93% of patients. Anticipatory prescribing was undertaken for pain relief in 91% of cases, for agitation in 84% of cases, for the prevention of respiratory tract secretions in 80% of cases, for nausea in 80% of cases and for breathlessness in 67% of cases. Inappropriate blood tests and antibiotics were discontinued in 87% and 91% respectively, and recording of ‘not for Cardio Pulmonary Resuscitation’ (where appropriate) documented in 93% of patients. In regard to ongoing care the presence or absence of symptoms could be recorded for patients during the last 24 hours of life. The status ... Fade Library blogs http://www.medworm.com/rss/comments.php?id=1128576 Thu, 03 Jan 2008 16:15:35 +0100 1128576 http://www.medworm.com/index.php?rid=623509&cid=t_135871_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F05%2F18%2Fangioplasty-vs-drug-therapy-could-one-be-better-than-the-other%2F Filed under: Prevention, American Heart Association, Research, Drugs, SurgeryBefore there were stents, angioplasty (without stents) and drugs were the two main weapons used to prevent a second heart attack. A small study in Switzerland found that when comparing groups of symptom-free heart attack survivors who were treated with angioplasty and drugs vs. intensive drug therapy alone found that those in the angioplasty group suffered fewer second heart attacks. But the American Heart Association isn't convinced. Calling the study "intriguing," an AHA spokesperson said the study was too small to be conclusive. In addition, because the patients in the study were treated over a decade ago, it doesn't take into account the advancements made in both types of therapy, as well as the addition of st... The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=623509 Fri, 18 May 2007 04:00:00 +0100 623509