MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'endogenous'. Sat, 03 Sep 2011 02:35:59 +0100 http://www.medworm.com/index.php?rid=4742151&cid=t_434226_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FtrJDCC5fq7w%2F Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease or Lou Gehrig’s disease, is a fatal disorder of unknown etiology. The disease involves degeneration of motor neurons, leading to paralysis, respiratory failure, and death within five years. A viral etiology for ALS has been suggested but never proven. Retroviruses have been considered because they cause motor neuron disease in mice, and HIV-1 and HTLV-1 cause ALS-like symptoms in humans. Sera from some ALS patients have been shown to contain elevated levels of reverse transcriptase, an enzyme found in retrovirus particles. RNAs encoding this enzyme have now been found in the brains of ALS patients, and their origin appears to be the human endogenous retrovirus HERV-K. Reverse transcriptase is a retroviral enzyme ... virology blog blogs http://www.medworm.com/rss/comments.php?id=4742151 Fri, 22 Apr 2011 16:40:03 +0100 4742151 http://www.medworm.com/index.php?rid=4723288&cid=t_434226_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2F6EfTXFJ1g-4%2F Discussion about CROI at ViroBlogy Land cover and West Nile virus disease (Am Journ Trop Med Hyg) Construction of recombinant poxviruses (Methods Mol Biol) Geographic Information System TWiV on Facebook Letters read on TWiV 129 Weekly Science Picks Rich – Polyxeni Potter and EID covers Dickson – American Museum of Natural History Alan – Moon Trees (EurekAlert! article) Vincent – Infection Landscapes Listener Picks of the Week Didier  - The Vaccines (MySpace) /Sven-Urban – The Science of Discworld by Terry Pratchett Garren – Omega Tau podcast Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twi... virology blog blogs http://www.medworm.com/rss/comments.php?id=4723288 Sun, 17 Apr 2011 15:46:13 +0100 4723288 http://www.medworm.com/index.php?rid=4531629&cid=t_434226_139_f&fid=38879&url=http%3A%2F%2Ftraffic.libsyn.com%2Ftwiv%2FTWiV122.mp3 Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Welkin Johnson On episode #122 of the podcast This Week in Virology, the complete TWiV crew teams up with Welkin Johnson to explore the other AIDS epidemic, infection of monkeys with simian immunodeficiency virus, and its restriction by the cellular protein TRIM5. Right click to download TWiV #122 (77 MB .mp3, 147 minutes). Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Edwin Kilbourne, MD, 1920-2011 Evolution of TRIM5-CypA in Old World monkeys (PLoS Pathogens) Balancing selection and evolution of Old World TRIM5 (PNAS) TRIM5 and cross-species transmission of a primate retrovirus (PLoS... virology blog blogs http://www.medworm.com/rss/comments.php?id=4531629 Sun, 27 Feb 2011 15:35:09 +0100 4531629 http://www.medworm.com/index.php?rid=4337542&cid=t_434226_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Ftraffic.libsyn.com%2Ftwiv%2FTWiV114.mp3 Hosts: Vincent Racaniello, Alan Dove, and Rich Condit On episode #114 of the podcast This Week in Virology, Vincent, Alan, and Rich revisit ten compelling virology stories of 2010. Right click to download TWiV #114 (64 MB .mp3, 88 minutes). Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio. Ten virology stories of 2010: XMRV, CFS, and prostate cancer (TWiV 113, 99, 98, 94, 89, 76, 70, 65) The ongoing saga of polio eradication (TWiV 110, 79) Viruses interact with the miRNA/siRNA system (TWiV 108, 72) Endogenous viruses – retro and beyond (TWiV 105, 91, 88, 65) Dengue virus progress and new outbreak (TWiV 111, 95, 82) Colony collapse disorder (TWiV 104) David Baltimore (TWiV 100) Ode... virology blog blogs http://www.medworm.com/rss/comments.php?id=4337542 Sun, 02 Jan 2011 17:43:12 +0100 4337542 http://www.medworm.com/index.php?rid=4121690&cid=t_434226_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Ftraffic.libsyn.com%2Ftwiv%2FTWiV105.mp3 Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit On episode #105 of the podcast This Week in Virology, Vincent, Dickson, Alan, and Rich review eradication of rinderpest, endogenous hepatitis B virus in the zebra finch genome, and identification of the cell receptor for an extinct retrovirus. Download TWiV #105 (66 MB .mp3, 92 minutes) Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio. Links for this episode: Eradication of rinderpest Rinderpest in the Merck Veterinary Manual Rinderpest summary (pdf) Manual on the preparation of rinderpest contingency plans Walter Plowright obituary The Plowright vaccine Measles evolution from rinderpest Endogenous hepadnaviruses in the ge... virology blog blogs http://www.medworm.com/rss/comments.php?id=4121690 Sun, 31 Oct 2010 17:55:39 +0100 4121690 http://www.medworm.com/index.php?rid=3911739&cid=t_434226_109_f&fid=34750&url=http%3A%2F%2Fpsychcentral.com%2Fblog%2Farchives%2F2010%2F08%2F27%2Fect-the-electric-personality-change%2F Patrice was misery incarnate. Unlike some of my depressed patients, who lived the proverbial life of quiet desperation, Patrice did not hide her suffering. She wept. She moaned. She regaled our walk-in clinic with a kind of biblical keening, which, understandably, attracted the attention of our clinic director. He took me aside one day and said, as gently as possible, “You really need to do something with that lady.” He was right, of course, and thus far I had done little to help Patrice, despite months of treatment. Aside from being poor and dealing with some physical limitations, Patrice had no discernible cause for her chronic depression. Her marriage was good, and despite her straitened circumstances, Patrice lived in a modest but comfortable home. Unlike many depressed patients, P... World of Psychology blogs http://www.medworm.com/rss/comments.php?id=3911739 Fri, 27 Aug 2010 16:26:14 +0100 3911739 http://www.medworm.com/index.php?rid=3762821&cid=t_434226_139_f&fid=38879&url=http%3A%2F%2Fwww.twiv.tv%2Fvincent.mp3 Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Welkin Johnson On episode #91 of the podcast This Week in Virology, Vincent, Dickson, Alan, Rich and Welkin discuss the nature, origin, and evolution of endogenous retroviruses (ERVs), and the recent finding of endogenous filovirus genomes in mammals. Download TWiV #91 (64 MB .mp3, 89 minutes) Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio. Links for this episode: Welkin blogs at Small Things Considered Constructing primate phylogenies from ancient retrovirus sequences (PNAS) Filoviruses are ancient and integrated into mammalian genomes (BMC Evol Biol) Synthetic cells: Momentous breakthrough or ethical morass? (To The ... virology blog blogs http://www.medworm.com/rss/comments.php?id=3762821 Sun, 18 Jul 2010 04:41:39 +0100 3762821 http://www.medworm.com/index.php?rid=3702851&cid=t_434226_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Fwww.twiv.tv%2FTWiV088.mp3 Hosts: Vincent Racaniello, Alan Dove, and Marc Pelletier On episode #88 of the podcast This Week in Virology, Vincent, Alan, and Marc discuss using a virus for beetle control, RNA based gene therapy for AIDS, and reconstitution of a endogenous human retrovirus. This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $75-$500 off a Drobo. To enter a drawing to receive 50% off the manufacturers suggested retail price of a Drobo S or FS at drobostore.com, fill out the questionnaire here. Download TWiV #88 (68 MB .mp3, 91 minutes) Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with Stitcher Radio. Links for this episode: Controlling the palm rhinoceros beetle with a virus The viro... virology blog blogs http://www.medworm.com/rss/comments.php?id=3702851 Sun, 27 Jun 2010 15:03:35 +0100 3702851 http://www.medworm.com/index.php?rid=3560233&cid=t_434226_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Flow-dose-naltrexone-medical-revolution-or-pseudoscience%2F2010.05.13 On SBM we have documented the many and various ways that science is abused in the pursuit of health (or making money from those who are pursuing health). One such method is to take a new, but reasonable, scientific hypothesis and run with it, long past the current state of the evidence. We see this with the many bogus stem cell therapy clinics that are popping up in parts of the world with lax regulation. This type of medical pseudoscience is particularly challenging to deal with, because there is a scientific paper trail that seems to support many of the claims of proponents. The claims themselves may have significant plausibility, and parts of the claims may in fact be true. Efforts to educate the public about such treatments are frustrated by the mainstream media’s lazy tendency to di... Better Health blogs http://www.medworm.com/rss/comments.php?id=3560233 Thu, 13 May 2010 12:00:52 +0100 3560233 http://www.medworm.com/index.php?rid=3166775&cid=t_434226_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2F7ABuOXRMEo4%2F The chromosomal DNA of several mammals has been found to contain sequences related to the nucleoprotein (N) gene of bornaviruses, enveloped viruses with a negative-strand RNA genome. I am amazed by this finding. How did bornaviral DNA get in our chromosomes, and what is it doing there? A search of the human genome sequence revealed DNA copies of the bornaviral N protein gene. This 370 amino acid viral protein is wrapped around the viral RNA, where it functions during RNA synthesis. Four different insertions of N protein DNA were found, all encoding proteins that are shorter than the viral counterpart.  DNA encoding bornaviral N protein was also found in the genomes of the chimpanzee, gorilla, orangutan, rhesus macaque, lemur, Garnett’s galago, African elephant, Cape hyrax, rat, mou... virology blog blogs http://www.medworm.com/rss/comments.php?id=3166775 Wed, 13 Jan 2010 15:22:03 +0100 3166775 http://www.medworm.com/index.php?rid=3163493&cid=t_434226_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2010%2F01%2Fretrovirus-book-published.html Published this month (January 2010):Retroviruses: Molecular Biology, Genomics and Pathogenesis Edited by: Reinhard Kurth and Norbert Bannert Published: 2010   ISBN: 978-1-904455-55-4Price: GB £159 or US $310 Written by the top retroviral specialists, this book reviews the genomics, molecular biology, and pathogenesis of these important viruses, comprehensively covering all the recent advances. Topics include: host and retroelement interactions, endogenous retroviruses, retroviral proteins and genomes, viral entry and uncoating, reverse transcription and integration, transcription, splicing and RNA transport, pathogenesis of oncoviral infections, pathogenesis of immunodeficiency virus infections, retroviral restriction factors molecular vaccines and correlates of protection, gamma... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=3163493 Tue, 12 Jan 2010 08:56:00 +0100 3163493 http://www.medworm.com/index.php?rid=2984913&cid=t_434226_122_f&fid=35068&url=http%3A%2F%2Fbrainwindows.wordpress.com%2F2009%2F11%2F11%2Fendogenous-dark-chromophore-imaging-via-modulated-simulated-emission%2F Here is an interesting paper, Imaging chromophores with undetectable fluorescence by stimulated emission microscopy, from Sunny Xie’s group.  They pump the sample with a excitation laser while simultaneously hitting it with a longer wavelength laser to induce stimuated emission. The pump laser is modulated at a high frequency which they can pick up and amplify with a lock-in amplifier. Theory and illumination schematic In two examples of imaging from a mouse ear, (above) shows the distribution of TBO, a photodynamic therapy drug, following drug administration, (below, red) shows the distribution of hemoglobin in blood vessles. How specific is the detection of endogenous chromophores?  They report that 60nm is the absolute detection limit, but this is for a pure chromophore in wa... Brain Windows blogs http://www.medworm.com/rss/comments.php?id=2984913 Thu, 12 Nov 2009 04:21:38 +0100 2984913