MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'enzyme'. Sat, 03 Sep 2011 01:59:48 +0100 http://www.medworm.com/index.php?rid=4394522&cid=t_102167_107_f&fid=36672&url=http%3A%2F%2Fwww.sciencebase.com%2Fscience-blog%2Fscience-news-with-a-spectral-twist-3.html , first 2011 issue of my spectroscopyNOW.com now live Fast-track walking pneumonia test – A new approach to testing for a common form of pneumonia using nanorod arrays to boost SERS signals can cut the time to diagnosis from several days to a mere ten minutes, according to research published in the journal Plos One. Conservation conversation – Improving storage and exposure conditions in conservation of artefacts is crucial to suppressing the fading and degradation of dyes and other components of paintings. Researchers have now used several analytical techniques, including attenuated total reflectance infrared spectroscopy, Raman spectroscopy, reflectance UV-Vis spectroscopy, X-ray fluorescence spectroscopy and optical microscopy, to investigate different conditions on common ... Sciencebase Science Blog blogs http://www.medworm.com/rss/comments.php?id=4394522 Thu, 06 Jan 2011 13:00:58 +0100 4394522 http://www.medworm.com/index.php?rid=3915307&cid=t_102167_160_f&fid=36189&url=http%3A%2F%2Fwww.skinmdblog.com%2F262%2Fwrinkle-prevention-is-smarter-than-fighting-wrinkles-after-theyve-formed%2F A better way than trying to get rid of lines and skin slackening once they have taken hold is practicing ongoing wrinkle prevention. The problem that people have with both stopping wrinkles from forming and eliminating them once they have already made their appearance is the lack of effective anti aging formulas.  Most of these products are made very cheaply, and therefore don’t contain what it is you need. The cosmetic industry is known for using the lowest quality ingredients possible in order to develop their formulas, so that they can maximize their profit margin.  This means that the formula they provide will primarily feature synthetics as ingredients, as the all natural compounds that a person needs in order to look younger require extensive processing. Only a few companies are ... Skin MD blogs http://www.medworm.com/rss/comments.php?id=3915307 Mon, 30 Aug 2010 11:43:07 +0100 3915307 http://www.medworm.com/index.php?rid=3907604&cid=t_102167_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fcan-the-expiration-date-of-harvested-organs-be-extended%2F2010.08.26 Currently, once a donated organ has been harvested it only has a few hours on ice before it “expires.” Lengthening this time period would be an incredible breakthrough that would allow patients in a wider area to potentially receive a transplant and also it would reduce some of the insanity surrounding the time pressures of organ transplantation. One proposed method of extending an organ’s shelf life is to alter the internal cell biology to allow cells to live longer at lower temperatures. The State University of New Jersey Rutgers-Camden just received a $385,419 grant from the NIH to study an enzyme system, AMP phosphatase, and how it can potentially create cold-tolerant Drosophila. The enzyme was originally identified in ice worms as the key enzyme that allows them to s... Better Health blogs http://www.medworm.com/rss/comments.php?id=3907604 Thu, 26 Aug 2010 12:00:26 +0100 3907604 http://www.medworm.com/index.php?rid=3896118&cid=t_102167_160_f&fid=36189&url=http%3A%2F%2Fwww.skinmdblog.com%2F255%2Fwass-your-wrinkle-cream-highly-rated-in-clinical-trials%2F Media coverage and production of anti wrinkle cream ratings in order to help people choose which product is best are in many cases leading the public astray. Oftentimes there is some sort of incentive mired in why a few specific products are chosen for these infamous “top ten lists”, and it more often than not has to do with either money or advertising dollars.  These products are not often selected because of their safety or effectiveness. Take the instant wrinkle removers that could cause you to lose part or total control over the muscles in your face as a perfect example.  The skin care products don’t help with the loss of collagen, elastin, or hyaluronic acid due to enzyme processes , and they don’t do a thing to boost tissue growth. Is it really worth ... Skin MD blogs http://www.medworm.com/rss/comments.php?id=3896118 Mon, 23 Aug 2010 13:33:36 +0100 3896118 http://www.medworm.com/index.php?rid=3757834&cid=t_102167_87_f&fid=36050&url=http%3A%2F%2Fblisstree.com%2Flive%2Ffeeling-full-10-ways-to-fight-the-bloat%2F photo: Thinkstock Bloating doesn’t just make us feel awkward about our bodies, it can also be physically uncomfortable. But we can try these tips to avoid bloating — we’d be willing to try anything to get rid of that tight-pants, always-full feeling. And share your own ways to fight the bloat in the comments section, below. Avoid salt. It makes you retain water and bloat up. Drink lots of water. If you’re hydrated, you’re body will avoid storing up lots of water. Ditch the straw. Drinking through a straw increases the amount of air you swallow, which would make you bloated. Don’t eat gassy foods. Carbonated drinks, lentils, wheat bran, and artichokes make you gassy (which can be more uncomfortable than bloating alone). Grab fiber. Eating fiber helps everyth... Breastfeeding 1-2-3 blogs http://www.medworm.com/rss/comments.php?id=3757834 Thu, 15 Jul 2010 20:40:17 +0100 3757834 http://www.medworm.com/index.php?rid=2862086&cid=t_102167_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F10%2Freverse-transcription.html Retroviruses are unique among animal viruses in that their replication requires the recombination of their own genetic material with that of the infected host cell. Two virus-encapsulated enzymes, reverse transcriptase and integrase, are dedicated to provirus formation. Reverse transcriptase, using a packaged cellular tRNA primer to initiate DNA synthesis from the viral RNA template, generates linear double-stranded DNA within the context of the reverse transcription nucleoprotein complex. The integrase enzyme processes the neo-synthesised DNA ends as the preintegration complex moves toward the cell nucleus. After finding a suitable chromatin acceptor site, the integrase recombines the processed DNA ends with a cell chromosome. For further details on the mechanisms of viral DNA synthesis, ... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2862086 Mon, 05 Oct 2009 10:58:00 +0100 2862086 http://www.medworm.com/index.php?rid=2295402&cid=t_102167_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2Fj4uxM6ckVXQ%2F Asians would know what I’m talking about. You drink a few sips of alcohol and suddenly, you feel nauseated and hot, you face turns beet red, and your heart beats faster. Known as the “Asian Glow” or “Asian Flush”, this reaction to alcohol is a risk factor for cancer of the esophagus, one of the deadliest in the world. The alcohol flushing response is an inherited genetic trait – deficiency in the enzyme aldehyde dehydrogenase 2 (ALDH2)- common among one third of Japanese, Chinese and Koreans. Here’s how the enzyme works: In normal individuals, alcohol is broken down into a non-toxic forms by the action of two enzymes. Alcohol dehydrogenase (ADH) oxidizes alcohol into acetaldehyde. Acetaldehyde is a carcinogen that causes DNA damage, so the final steps in the metabolism of a... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2295402 Wed, 25 Mar 2009 14:26:56 +0100 2295402 http://www.medworm.com/index.php?rid=2187748&cid=t_102167_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D6147 Scientists in Japan have identified an enzyme which appears to suppress breast cancer and they hope the finding will spur new therapies to control the second most common cancer in the world.read more | digg story from the Malaysian Medical Resources Japan scientists identify cancer-suppressing enzyme (Source: Malaysian Medical Resources) Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=2187748 Sat, 14 Feb 2009 05:00:00 +0100 2187748 http://www.medworm.com/index.php?rid=2060979&cid=t_102167_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D5676 Swedish researchers have found that an enzyme that aids sexual performance in human males helps spruce trees develop stronger root systems. Think we can all agree we don’t need healthy spruce treesread more | digg story from the Malaysian Medical Resources Enzyme good for sex also good for trees (Source: Malaysian Medical Resources) Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=2060979 Mon, 22 Dec 2008 05:00:00 +0100 2060979 http://www.medworm.com/index.php?rid=1863027&cid=t_102167_149_f&fid=35784&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FTheChemBlog%2F%7E3%2F414995883%2F Well deserved, Roger Tsein, Osamu Shimomura and Martin Chalfie will share the prize for their work on GFP.  The work is seminal in many regards, not the least of which is because it makes shit glow and glowing is way cooler then Pd couplings.  It’s important to note that I think Tsein should STILL RESPOND TO EMAILS no matter how many stupid fucking prizes he wins.  But that’s fine. GFP is a very interesting molecule with amazingly bizarre chemistry at its core.  Central to the protein is a fluorphore - a conjugated heteroaromatic cluster - that emits green light.  Roger’s first publication on the subject was in 1995, iirc, so it took him a little more than 10 years to snag the highest honor in sciences for his efforts.  The detailed mechanisms of the actual biosynth... The Chem Blog blogs http://www.medworm.com/rss/comments.php?id=1863027 Wed, 08 Oct 2008 21:51:33 +0100 1863027 http://www.medworm.com/index.php?rid=1531951&cid=t_102167_107_f&fid=36698&url=http%3A%2F%2Fminingdrugs.blogspot.com%2F2008%2F06%2Fopenastexviewer.html As posted by Noel and Rich was the Java-based AstexViewer just got LGPLed and voila! Here it is, the OpenAstexViewer for structure-based drug design.I personally was especially interested in the electron density functionality and how easy it would be creating a view on an enzymatically active-site.As example I used Lisinopril an ACE (Angiotensin-converting enzyme) inhibitor. This class is seen as one of the success stories of rational drug design, based on the structural biology of carboxypeptidase A and medicinal chemistry.My first thought was using Captopril, the initial drug for this class, but I could not find an electron density map and had to pick another example. Since the PDB structure (2C6N) of Lisinopril has a deposited electron density map this was now used.After downloading the... Mining Drug Space blogs http://www.medworm.com/rss/comments.php?id=1531951 Thu, 19 Jun 2008 17:58:00 +0100 1531951 http://www.medworm.com/index.php?rid=1461250&cid=t_102167_149_f&fid=35784&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FTheChemBlog%2F%7E3%2F295529089%2F It has been a while, but I knew that the AMAZING quality coming out of the journal of Food Chemistry would get me to come back for more.  Indeed, a great one from Yaguang Luo (DOI: 10.1016/j.foodchem.2008.02.070) taught me just oodles of facts: Enzymatic browning is a widespread color reaction occurring in fruits and vegetables and tea leaves. The browning reaction requires the presence of oxygen, phenolic compounds and polyphenol oxidases (PPO) and is usually initiated by the enzymatic oxidation of monophenols into o-diphenols and o-diphenols into quinones, which undergo further non-enzymatic polymerization leading to the formation of pigments. Although enzymatic browning is beneficial to the color and flavor development of certain food items such as tea, coffee and cocoa, it impairs the... The Chem Blog blogs http://www.medworm.com/rss/comments.php?id=1461250 Thu, 22 May 2008 03:41:44 +0100 1461250 http://www.medworm.com/index.php?rid=1030201&cid=t_102167_151_f&fid=35823&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FAddictionInbox%2F%7E3%2F185381961%2Fcyp2d6-factor.html Enzymes And Drug AbuseDifferent drugs effect different people differently.Drugs are broken down into their constituent waste products by specific sets of enzymes. A subset of the human population, variously estimated at 3% to 7%, are categorized as “poor metabolizers.” For them, a drug’s recommended dosage is often far too high. The culprit is a gene variant that codes for a liver enzyme called cytochrome P450 isoenzyme 2D6, known in shorthand as CYP2D6. Poor metabolizers produce less of this crucial enzyme, which means that drugs are broken down and excreted at a much slower pace. In these people, the recommended dose results in higher drug concentrations. This obviously can make a crucial difference in how a person reacts to the drugs.About one out of 20 people has a mutation in th... Addiction Inbox blogs http://www.medworm.com/rss/comments.php?id=1030201 Thu, 15 Nov 2007 19:32:00 +0100 1030201 http://www.medworm.com/index.php?rid=802195&cid=t_102167_132_f&fid=35006&url=http%3A%2F%2Fnsaunders.wordpress.com%2F2007%2F08%2F16%2Fbioinformaticians-take-heart%2F It’s difficult for bioinformaticians to publish in so-called “high impact” journals at all, never mind as first author. Many of us are not group leaders with tightly-defined research programs; we are the “go to” guys, happy to apply our skills to any dataset that comes our way. In academia at least, we’re caught somewhere between research scientist and IT support. It can be a frustrating life. So it’s good to see that Nature, a journal not renowned for publishing articles with a strong computational biology component, has seen fit to publish this: Structure-based activity prediction for an enzyme of unknown function Hermann, JC et al. (2007) Nature 448: 775-779. Abstract | Full text | N & V It’s a fascinating piece of work. The authors ... What You're Doing Is Rather Desperate blogs http://www.medworm.com/rss/comments.php?id=802195 Thu, 16 Aug 2007 03:20:42 +0100 802195 http://www.medworm.com/index.php?rid=707363&cid=t_102167_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F07%2F01%2Frecipe-for-healthy-living-roasted-brussel-sprouts%2F Filed under: Colon and Rectal Cancer, Prevention, All Cancers, Nutrition, Cancer prevention foods, Vitamins and nutrients, Recipe Healthy LivingBrussel sprouts contain good amounts of vitamin A, vitamin C, folic acid and dietary fiber. Moreover, they are believed to protect against colon cancer, due to their containing sinigrin. They contain three types of phyto's, all shown to have either protective qualities against cancer, or enzyme producing qualities that have been shown during research to fight cancer cells in different ways.When boiling foods they tend to lose some of the vitamins and nutrients into the water. So here is a roasted brussel sprout recipe that is very easy to prepare and the brussel sprouts keep their natural nutty flavor.Vicki's Roasted Brussel Sprouts1 lb Brussels sp... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=707363 Sun, 01 Jul 2007 04:00:00 +0100 707363 http://www.medworm.com/index.php?rid=623510&cid=t_102167_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F05%2F18%2Fthe-enzyme-that-slows-a-racing-heart-naturally%2F Filed under: Daily newsIt seems like pacemakers and other implanted devices like ICD's have been in the news a lot lately, for different reasons. Here is some good news that is somewhat related, and may mean that in the future some people will get to avoid surgery: scientists have discovered an enzyme that works to put the brakes on a racing heartbeat. A person's heart rate is set by a single cell within the heart, called the pacemaker cell, and a naturally occurring enzyme called Pak 1 has been found to interact specifically with that cell -- telling it to slow things down.This discovery will obviously have a potentially huge effect on treatments, drugs, and the lives of people living with heart disease.Read | Permalink | Email this | Linking Blogs ... The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=623510 Fri, 18 May 2007 04:00:00 +0100 623510 http://www.medworm.com/index.php?rid=623480&cid=t_102167_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F05%2F18%2Fdiabetes-drug-may-be-fast-tracked-for-breast-cancer%2F Filed under: Breast Cancer, Drug, Research, Daily newsDrugs currently in trials for obesity and diabetes may soon be fast-tracked for use in the fight against breast cancer. Typically, it takes many years to research and develop new drugs. But these already-developed drugs, if successful, could reach the market much quicker.The drugs, believed to work by blocking the enzyme PTP1B, could help breast cancer patients because the enzyme is found in high levels in about 40 percent of these patients.Studies on mice show blocking production of the enzyme significantly slowed tumor development. In some cases, it stopped the spread of the cancer and it might even stop some tumors from forming.This is "very important and surprising," says one researcher who remarked that the excitement over this dis... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=623480 Fri, 18 May 2007 04:00:00 +0100 623480 http://www.medworm.com/index.php?rid=602388&cid=t_102167_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F05%2F10%2Fno-more-fat-free-dieting%2F Filed under: ResearchScientists have found a way for mice to eat whatever kind and however much fat in their diets and still not run any risk of getting heart disease. They deleted the gene that produces the enzyme ACAT2, which usually works in the body by converting cholesterol and other fats into forms that stick more easily and sometimes end up causing blocked vessels.Of course, like all studies based on mice, there's no word yet if the same principles will hold true in people. The hope is obviously that it does, and that a drug can be developed to inhibit the enzyme in humans, therefore reducing or maybe even eliminating a person's risk for developing heart disease.Here's to hoping! That would big.Read | Permalink | Email this | Linking Blogs |&n... The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=602388 Thu, 10 May 2007 04:00:00 +0100 602388 http://www.medworm.com/index.php?rid=480944&cid=t_102167_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F03%2F18%2Fblood-pressure-treatment-helps-shrink-lung-cancer-tumors%2F This study, published in the journal Cancer Research, is the first demonstration of the effect in animals.Read | Permalink | Email this | Linking Blogs | Comments (Source: The Cancer Blog) The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=480944 Sun, 18 Mar 2007 04:00:00 +0100 480944 http://www.medworm.com/index.php?rid=478744&cid=t_102167_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F03%2F14%2Fstop-your-insulin-inhibitions%2F Filed under: Type 2, Adult Onset, Diet, Lifestyle, ResearchKnocking out the gene for a peptide associated with insulin was shown to protect mice against the harmful effects of a high-fat diet. Urocortin 3 plays a role in the increased production of insulin in response to high caloric intake in animals. Scientists found that by removing the urocortin 3 gene from mice, they did not develop the age-related insulin resistance and high blood sugar observed in the normal control mice. The metabolisms of normal mice were compared to the metabolisms of those without the urocortin 3 gene. When placed on a high caloric diet for three months, the mice without the urocortin 3 gene packed on the same amount of weight but had lower insulin levels. But these mice also had lower blood sugar, improved gluc... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=478744 Wed, 14 Mar 2007 04:00:00 +0100 478744