MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'flu vaccine'. Sat, 03 Sep 2011 02:03:35 +0100 http://www.medworm.com/index.php?rid=4424238&cid=t_142092_87_f&fid=39261&url=http%3A%2F%2Fvactruth.com%2F2011%2F02%2F01%2Ffearful-uk-healthcare-workers-refuse-flu-vaccine-us-nurse-fired%2F The side effects of the flu vaccine have been causing many UK healthcare workers to question its safety. The latest figures show the uptake for the vaccine has been as low as 26%. Professor David Salisbury, director of immunization, told Nursing Times that the healthcare professionals were making a big mistake and risked not only their own lives, but the lives of their patients. (http://www.nursingtimes.net/nursing-practice…) Salisbury, a firm believer in vaccines, represents the Joint Committee on Vaccination and Immunizations as the Medical Secretary for the Department of Health. The JCVI is an independent expert advisory committee that advises Ministers on matters relating to the provision of vaccination and immunisation services. This means that Professor Salisbury would have ful... vactruth.com blogs http://www.medworm.com/rss/comments.php?id=4424238 Tue, 01 Feb 2011 15:57:17 +0100 4424238 http://www.medworm.com/index.php?rid=4352713&cid=t_142092_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fthe-slippery-slope-of-anti-vaccine-complacency%2F2011.01.15 I got a package in the mail today: My very own (complimentary) copy of Paul Offit’s new book, “Deadly Choices; How the Anti-Vaccine Movement Threatens Us All.” Needless to say, I can’t wait to read it. Not coincidentally, Dr. Offit has been making the rounds of interviews in the wake of the book’s release. Although I haven’t heard any of them directly, I did see a reference to this NPR interview on the FaceBook page of an old friend, who quoted from it thusly: IRA FLATOW:  You write that some pediatricians will not see kids who are not vaccinated. Is that a good solution to the problem? DR. PAUL OFFIT: I don’t know what’s a good solution to that problem. And I feel tremendous sympathy for the clinician who’s in private practice. On the one hand, and my wife sort ... Better Health blogs http://www.medworm.com/rss/comments.php?id=4352713 Sat, 15 Jan 2011 15:00:02 +0100 4352713 http://www.medworm.com/index.php?rid=4343127&cid=t_142092_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Finfluenza-its-not-just-the-flu%2F2011.01.13 One of our readers suggested that I review the book The Great Influenza: The Epic Story of the Deadliest Plague in History, by John M. Barry. It’s not a new book (it was published in 2004) but it is very pertinent to several of the issues that we have been discussing on this blog, especially in regards to the current anti-vaccine movement. It’s well worth reading for its historical insights, for its illumination of the scientific method, and for its accurate reporting of what science has learned about influenza. In the great flu epidemic of 1918, influenza killed as many people in 24 weeks as AIDS has killed in 24 years. It’s hard to even imagine what that must have been like, but this book helps us imagine it. It tells horror stories: Children found alone and starving beside the cor... Better Health blogs http://www.medworm.com/rss/comments.php?id=4343127 Thu, 13 Jan 2011 20:00:51 +0100 4343127 http://www.medworm.com/index.php?rid=4302944&cid=t_142092_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FnGdRrBA1bCU%2F photo: Thinkstock If you happen to be traveling in the U.K. these days, you may want to bring along some over-the-counter cold and flu medicine. In just the last week, there’s been a 60% increase in people who are critically ill with the flu in Britain (from 460 to 738). Most of those patients had not been vaccinated and were in high-risk groups for certain strains of the flu. In all, almost 40 people in the U.K. died from the flu in 2010. I just spent the Christmas holidays in London and Brighton, and can personally attest that everywhere I went (hotel, pub, restaurant, shop, train, tube) there was at least one person sitting next to me who was sneezing into a tissue or coughing into a handkerchief. (I also went to Paris, and the same was true there.) Unfortunately, toward the end o... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=4302944 Sun, 02 Jan 2011 00:34:35 +0100 4302944 http://www.medworm.com/index.php?rid=4302127&cid=t_142092_87_f&fid=39261&url=http%3A%2F%2Fvactruth.com%2F2010%2F12%2F31%2Fgovernment-against-giving-children-flu-vaccine%2F News in from the UK government. Last night ministers and senior government advisers ruled against the flu vaccine for children under five. Their decision was made despite the current flu epidemic in the UK. Reports say that 39 people have died from flu since October, four of these were under the age of five. Daily Mail reporter Sophie Borland who took up the story wrote (http://www.dailymail.co.uk/health…): “The latest figures show that an epidemic has now broken out among children under four and levels have reached a ten-year high. But ministers and senior Government advisers last night ruled that the immunisation programme for those aged six months to five years – which was quietly cancelled earlier this year – would not have significant ‘gain’.” Why the sudden turn aro... vactruth.com blogs http://www.medworm.com/rss/comments.php?id=4302127 Sat, 01 Jan 2011 00:39:25 +0100 4302127 http://www.medworm.com/index.php?rid=4285203&cid=t_142092_87_f&fid=39261&url=http%3A%2F%2Fvactruth.com%2F2010%2F12%2F23%2Fsanofi-pasteur-plays-santa-and-pays-for-children-to-take-part-in-vaccine-trials%2F With Christmas nearly here and the flu season well and truly under way, Sanofi Pasteur is playing Santa Claus this year. Not only is the drug giant offering free flu vaccines to children, but they are paying parents $350 to use them as guinea pigs in flu vaccine trials. With many health departments already out of flu vaccines this year, parents in Overland Park, Kansas are allowing their children to have the untested vaccines instead. One official said clinical trials may be the way to go for some parents. Radiant Research is conducting phase three testing of a new quadrivalent influenza vaccine. Dr. Carl Petit, the lead investigator for Radiant Research, reassures parents that the side effects, if any, are only minimal. A parent will rake in $350 per child (between the ages of six months ... vactruth.com blogs http://www.medworm.com/rss/comments.php?id=4285203 Thu, 23 Dec 2010 22:21:49 +0100 4285203 http://www.medworm.com/index.php?rid=4245011&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FsoDQyobQdZg%2F Influenza researcher Peter Palese visited yesterday and spoke about “Pandemic influenza: Past and Future”. A key part of his talk was a review of his efforts to produce a universal influenza vaccine which protects against all strains. He used the following graph to make the point that when influenza pandemic strains emerge, there is insufficient time to deliver a vaccine using current technology. Image source: CIDRAP The graph depicts the percentage of visits for influenza-like illness (ILI – the red line) and distribution of the swine-origin influenza vaccine (blue line) from September 2009 to May 2010 in the US. At the peak of ILI at the end of October 2009, fewer than 20 million doses of vaccine had been shipped. By the time 120 million doses had been distributed, infe... virology blog blogs http://www.medworm.com/rss/comments.php?id=4245011 Thu, 09 Dec 2010 17:15:05 +0100 4245011 http://www.medworm.com/index.php?rid=4197073&cid=t_142092_87_f&fid=39261&url=http%3A%2F%2Fvactruth.com%2F2010%2F11%2F22%2Fhow-government-and-pharmaceutical-companies-gamble-with-your-childs-life%2F The large number of adverse reactions to influenza vaccine this year led the government to suspend the vaccine for children across Australia. Nationally, there were 1,729 adverse events reported to the Therapeutic Goods Administration (TGA). After analysis the TGA stated there were 1,152 reports of fever and 123 reports of convulsions in children under 5 within 24 hours of the vaccine being administered. In Western Australia (WA) 517 children had adverse reactions, of which 72 had febrile convulsions. Prof. Collignon, director of the infectious diseases unit at Canberra hospital states that this is a very high rate of adverse reactions when the risk of dying of swine flu last winter was one in a million). The adverse reactions were linked to CSL’s 2010 trivalent influenza vaccine Fluvax ... vactruth.com blogs http://www.medworm.com/rss/comments.php?id=4197073 Mon, 22 Nov 2010 22:50:50 +0100 4197073 http://www.medworm.com/index.php?rid=4125008&cid=t_142092_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fvaccines-top-10-reasons-to-get-your-shots%2F2010.11.01 Vaccines have saved more lives than any other medical intervention in history. They are incredibly safe and effective and are well-tolerated by most people. In the US, the Centers For Disease Control and Prevention (CDC) carefully reviews all reports of adverse reactions that could be associated with vaccines. Over decades of review, they have found that the rate of potential severe reactions is so low that they cannot even calculate a risk. There are many vaccines available for babies, children, and adults. Please check these vaccine schedules to make sure that you and your family are fully protected from vaccine-preventable diseases. (Or you can ask your doctor/nurse to review your vaccine needs with you in person.) Vaccines for ages 0-6 click here. Vaccines for ages 7-18 click here. Vac... Better Health blogs http://www.medworm.com/rss/comments.php?id=4125008 Mon, 01 Nov 2010 17:00:32 +0100 4125008 http://www.medworm.com/index.php?rid=4096785&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FvAP_q8lu_8s%2F After my lecture on influenza pathogenesis and evolution at the Northeast Laboratory Conference 2010 in Portland, Maine, I was asked if it is necessary to receive the influenza vaccine every year. This question was precipitated by my statement that the 2010-11 trivalent influenza vaccine contains the same swine-origin H1N1 strain as last year’s monovalent vaccine. That virus has not undergone sufficient antigenic drift to necessitate the formulation of a new vaccine. There are two main considerations* when deciding whether to be immunized yearly against influenza: the nature of the vaccine and age of the recipient. Last year’s seasonal influenza vaccine for the northern hemisphere contained the following strains: A/Brisbane/59/2007 (H1N1) A/Brisbane/10/2007 (H3N2) B/Brisbane/60/2008 ... virology blog blogs http://www.medworm.com/rss/comments.php?id=4096785 Fri, 22 Oct 2010 21:59:55 +0100 4096785 http://www.medworm.com/index.php?rid=4074068&cid=t_142092_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Funscientific-medicine-what%25e2%2580%2599s-the-harm%2F2010.10.14 Any promoter of science-based medicine often faces the question: “What’s the harm?” What is the harm if people try treatment modalities that are not based upon good science, that are anecdotal, or provide only a placebo benefit? There are generally two premises to this question. The first is that most “alternative” placebo interventions are directly harmless. The second is that direct harm is the only type worth considering. Both of these premises are wrong. The pages of Science Based Medicine (SBM) are filled with accounts of direct harm from unscientific treatments: Argyria from colloidal silver, death from chelation therapy, infection or other complications from acupuncture, burns from ear candleing, stroke from chiropractic neck manipulation — the list goes on. ... Better Health blogs http://www.medworm.com/rss/comments.php?id=4074068 Thu, 14 Oct 2010 14:00:50 +0100 4074068 http://www.medworm.com/index.php?rid=4018185&cid=t_142092_87_f&fid=39261&url=http%3A%2F%2Fvactruth.com%2F2010%2F09%2F30%2Ftall-tales-and-other-vaccine-myths%2F Catherine J. Frompovich Vactruth.com 09/30/2010 Autumn finally has arrived in the Northern Hemisphere in 2010 along with admonitions to get the annual flu vaccination to prevent contracting any of the various strains that now circumnavigate the globe, including one or two that may have resulted from scientific ‘tinkering’. Daily, if not hourly, prompts appear on radio and television about going to a local pharmacy or other health care facility to get immunized. The fear campaign has begun in earnest and, naturally, we need to wonder about the scientific facts associated with vaccine research and flu vaccines, in particular. So let’s examine some of the tall tales and other vaccine myths that also circumnavigate the globe as part of media flu hype and spin. Children Are parents aware ... vactruth.com blogs http://www.medworm.com/rss/comments.php?id=4018185 Thu, 30 Sep 2010 14:19:11 +0100 4018185 http://www.medworm.com/index.php?rid=3998996&cid=t_142092_87_f&fid=39261&url=http%3A%2F%2Fvactruth.com%2F2010%2F09%2F24%2Fflu-vaccine-caused-over-1000-adverse-reactions%2F Christina England Vactruth.com 09/24/2010 Yesterday, the Sydney Herald reported an astounding 1000 plus reports of adverse reactions following the flu vaccine, Fluvax. These reports included 100 reports of febrile convulsions. In her report, journalist Carol Bennett stated: “It showed the CSL-produced Fluvax and Fluvax Junior may have caused two to three hospital admissions due to seizure for every admission from flu it prevented”. // Febrile convulsions are caused when a child’s body rapidly overheats resulting in a seizure. The NetDoctor website gives insight into what a child suffering from a febrile convulsion looks like: The attack often begins with the child losing consciousness, and shortly afterwards the body, legs and arms go stiff. The head is thrown backwards and t... vactruth.com blogs http://www.medworm.com/rss/comments.php?id=3998996 Fri, 24 Sep 2010 19:05:03 +0100 3998996 http://www.medworm.com/index.php?rid=3976502&cid=t_142092_87_f&fid=39261&url=http%3A%2F%2Fvactruth.com%2F2010%2F09%2F14%2Fvaccine-acceptance-statistics-for-2009%2F Catherine Frompovich Vactruth.com 09/14/2010 There’s an adage that goes something like this: You can fool some of the people some of the time, but you can’t fool all the people all the time. Well, there just may be a report that bears out that contention, in my opinion. Recently I came across The Rand Corporation’s November 2009 report Seasonal Influenza Vaccine Use by Adults in the U.S., which I’d like to parse. First and foremost, I found it interesting that the Rand survey was “conducted under contract with GlaxoSmithKline (GSK).” On the front page of that report this statement appears: The RAND Corporation is a nonprofit research organization providing objective analysis and effective solutions that address the challenges facing the public and private sectors around the wor... vactruth.com blogs http://www.medworm.com/rss/comments.php?id=3976502 Tue, 14 Sep 2010 06:30:50 +0100 3976502 http://www.medworm.com/index.php?rid=3929168&cid=t_142092_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2010%2F09%2Finformation-2010-flu-season-vaccine%2F Some tips on the getting the flu vaccine this year and getting covered for H1N1. (Source: Inside Surgery) Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=3929168 Fri, 03 Sep 2010 03:23:40 +0100 3929168 http://www.medworm.com/index.php?rid=3895841&cid=t_142092_87_f&fid=34872&url=http%3A%2F%2Fblisstree.com%2Ffeel%2F196462%2F Sleepy Swine Flu: The H1N1 vaccine could be linked to narcolepsy. (via Mercola Blog) Post from: BlissTree (Source: Healthbolt) Healthbolt blogs http://www.medworm.com/rss/comments.php?id=3895841 Mon, 23 Aug 2010 15:40:18 +0100 3895841 http://www.medworm.com/index.php?rid=3831561&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FxXce5vGUKuo%2F And so another work week will soon draw to a close. And not a moment too soon. There is much tidying up to do around the Pharmalot corporate campus. Moreover, we look forward to a respite in order to catch up on some reading and tend to the shortest of short people. What about you? Any special plans? Gearing up for vacation, perhaps? Whatever you do, enjoy. And see you soon… Cypress Bioscience Rejects Ramius Buyout Offer (Reuters) Glaxo Signs Dry Powder Deal With Vecture (PharmaTimes) Teva Version Of Lovenox Due Shortly (Reuters) ACIP Says CSL Flu Shot For Kids To Be Avoided (Associated Press) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3831561 Fri, 06 Aug 2010 12:07:31 +0100 3831561 http://www.medworm.com/index.php?rid=3767014&cid=t_142092_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2010%2F07%2Fdr-mark-prausnitz-working%2F Dr. Mark Prausnitz of Georgia Tech and colleagues are working on patch that can deliver the seasonal flu vaccine to replace the need to stick people with needles in the arm to administer it. The patches, which are at least five years away from market, would deliver the flu vaccine via microneedles that pierce through the skin after being placed for about ten minutes. (Source: Inside Surgery) Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=3767014 Mon, 19 Jul 2010 23:33:22 +0100 3767014 http://www.medworm.com/index.php?rid=3676899&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FZRxrE7wS55A%2F Good morning, everyone. How are you today? The weekend is just around the corner, of course, and that means looking ahead to…. what? We expect to frolic with some industry types at a soiree and, otherwise, lounge around the Pharmalot corporate campus to catch up on some reading. As for you, we hope your plans are exciting. Meanwhile, here are a few news items of the world. Have a great time and, by the way, do remember to call Dad… Sanofi-Aventis Prostate Cancer Drugs Wins FDA Approval (Reuters) UK’s NICE Approves Amgen’s Prolia (Bloomberg News) Walgreens Launches Mobile Prescription Reminders (EWeek) Malaysia Forecast To Lead Generics Growth In Asia (PharmaTimes) Pharma Urged To Develop More Orphan Drugs (Bloomberg News) Pfizer Biotech Drug Tops Placebo In Knee Pai... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3676899 Fri, 18 Jun 2010 11:48:30 +0100 3676899 http://www.medworm.com/index.php?rid=3671695&cid=t_142092_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fwho-and-h1n1-conflict-of-interest%2F2010.06.17 On June 11, 2009, Dr. Margaret Chan, the director general of the World Health Organization (WHO), declared that the H1N1 flu that was then spreading around the world was an official pandemic. This triggered a series of built-in responses in many countries, including stockpiling anti-viral medications and preparing for a mass H1N1 vaccination program. At the time the flu was still in its “first wave” and the fear was that subsequent waves, as the virus swept around the world, would become more virulent and/or contagious –- similar to what happened in the 1918 pandemic. This did not happen. At least our worst fears were not realized. The H1N1 pandemic, while serious, simmered through the winter of 2009-2010, producing a less than average flu season, although with some worrisome differe... Better Health blogs http://www.medworm.com/rss/comments.php?id=3671695 Thu, 17 Jun 2010 14:00:41 +0100 3671695 http://www.medworm.com/index.php?rid=3570060&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FeNQ5UJZLh9c%2F A controversy appears to be emerging in Australia over payments made to parents who have enrolled children as young as six months old in H1N1 flu vaccine trials sponsored by GlaxoSmithKline. In some instances, parents were enrolling three children at a time and receiving $900, according to The Herald Sun, which notes the payments may breach national ethical guidelines. Parents of healthy children up to 10 years old are receiving $300 for each child to participate in the trial, which involves two needles, two blood tests and medical monitoring for each child. A spokeswoman for AusTrials, which runs the trials for Glaxo, confirmed to the paper that the payments were made and that, so far, 110 children participated. However, an anonymous critic complained to the Sun that parents were, effecti... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3570060 Mon, 17 May 2010 15:40:16 +0100 3570060 http://www.medworm.com/index.php?rid=3457791&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Fwww.twiv.tv%2FTWiV077.mp3 Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich revisit circovirus contamination of Rotarix, then discuss poxvirus-like replication of mimivirus in the cell cytoplasm, and whether seasonal influenza immunization increases the risk of infection with the 2009 H1N1 pandemic virus. This episode is sponsored by Data Robotics Inc. Use the promotion code TWIVPOD to receive $50 off a Drobo or $100 off a Drobo S. Win a free Drobo S! Contest rules here. Download TWiV #77 (60 MB .mp3, 83 minutes) Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email. Links for this episode: Contamination of Rotarix vaccine with porcine circovirus 1 DNA Do you want to know what is in your vaccines? Take the poll Mimivirus replicates in the cell cytopl... virology blog blogs http://www.medworm.com/rss/comments.php?id=3457791 Sun, 11 Apr 2010 14:36:56 +0100 3457791 http://www.medworm.com/index.php?rid=3342895&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2F9mZdMGJ-j_o%2F Welcome to the working week. We hope your weekend was pleasant and relaxing. Now, though, the routine has returned - deadlines and meetings beckon. To prepare, we are brewing the required cup of stimulation. So grab one yourself, or perhaps a bottle of water is preferred, and get ready for the plunge. Meanwhile, here are a few items to help you along. Have a great day, everyone… Roche Suspends Rheumatoid Arthritis Drug Trial After Deaths (Reuters) AstraZeneca’s Colon Cancer Drug Fails Test (Bloomberg News) Pfizer’s Jeff Kindler Woos Ratiopharm (Reuters) A ‘Miracle’ Cancer Drug At $48,000 (Bloomberg News) Xenoport To Cut Staff By Half (San Jose Business Journal) Dutch Government Wants To Sell Flu Vaccines Back (Reuters) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3342895 Mon, 08 Mar 2010 13:36:06 +0100 3342895 http://www.medworm.com/index.php?rid=3266701&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FNzr5kGw2Wnw%2F Influenza A viruses typically cause severe respiratory disease mainly in the very young or the elderly. The 2009 swine-origin H1N1 virus is unusual because it preferentially infects individuals under 35 years of age. We’ve previously noted that being older is a good defense against 2009 H1N1 influenza virus, in part because older people have antibodies that block infection. Experiments done in mice show that immunization with 1918-like or classical H1N1 swine influenza viruses protects against infection with 2009 H1N1 virus. When mice are inoculated intranasally with a high dose of the 2009 H1N1 influenza virus, the virus replicates in the lungs and leads to significant weight loss and lethality. After a sublethal virus dose the mice develop protective antibodies that protect agains... virology blog blogs http://www.medworm.com/rss/comments.php?id=3266701 Thu, 11 Feb 2010 20:17:26 +0100 3266701 http://www.medworm.com/index.php?rid=3250975&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Fwww.twiv.tv%2FTWiV069.mp3 Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich review recent outbreaks of mumps in the UK, US, and Israel, protection of mice against 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 vaccines, and a virus-like particle vaccine for chikungunya virus. This episode is sponsored by Data Robotics Inc. Use the promotion code VINCENT to receive $50 off a Drobo or $100 off a Drobo S. Win a free Drobo S! Contest rules here. Download TWiV #69 (59 MB .mp3, 82 minutes) Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email. Links for this episode: Mumps outbreak in Israel (ProMedMail and Eurosurveillance; thanks Lenn!) and Iowa Retraction of Wakefield vaccines- autism study Immunization with 1918-like and classical sw... virology blog blogs http://www.medworm.com/rss/comments.php?id=3250975 Mon, 08 Feb 2010 03:22:28 +0100 3250975 http://www.medworm.com/index.php?rid=3175595&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Fwww.radiosandysprings.com%2Fpodcasts%2FInfectiousDiseaseJan04.2010.mp3 I was recently interviewed on Radio Sandy Springs by Sharon Sanders of FluTrackers. We talked about pandemic influenza H1N1 virus. Listen to the show below. Download Infectious Disease Hour January 4 2010 (20 MB .mp3, 57 minutes) Radio Sandy Springs 1620 AM is a low-powered Atlanta-based talk radio station that simulcasts on the Internet.  They broadcast a weekly ‘Infectious Disease Update’ with interviews with clinicians, scientists, researchers, and even historians. You can find an archive of recent Infectious Disease Hour shows here. (Source: virology blog) virology blog blogs http://www.medworm.com/rss/comments.php?id=3175595 Thu, 14 Jan 2010 22:00:33 +0100 3175595 http://www.medworm.com/index.php?rid=3146211&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2Fg1TfFi2DmLU%2F Nice to see you again. Hope the day is getting off to a good start. It is the middle of the week, though, and after the holiday break, this can only mean one thing - lots of meetings, deadlines and projects to prepare. So as you dig in, here are a few things to help you along. As for us, the time has come for a cup of stimulation. May your day go well… Europe Seeks To Reduce H1N1 Vaccine Inventory (SwissInfo.ch) Glaxo Centralizes HR Functions (EmployeeBenefits.co) WARF Wins Patent Lawsuit Over Enzyme (Chicago Tribune) FDA Cancels Panel Review For Cymbalta (Reuters) Glaxo’s Witty Succeeds Higgins As EFPIA Chief (PharmaTimes) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3146211 Wed, 06 Jan 2010 12:50:31 +0100 3146211 http://www.medworm.com/index.php?rid=3139244&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FBhRTdzgW53Y%2F That’s the contention by more than a dozen members of the Parliamentary Assembly of the Council of Europe, which reportedly plans to conduct an inquiry into the influence that drugmakers may have had on the World Health Organization, scientists and governments. A resolution was introduced last month by Wolfgang Wodarg, a member of Germany’s Social Democratic Party who chairs the PACE health committee, and it reads: “In order to promote their patented drugs and vaccines against flu, pharmaceutical companies have influenced scientists and official agencies, responsible for public health standards, to alarm governments worldwide. They have made them squander tight health care resources for inefficient vaccine strategies and needlessly exposed millions of healthy people to th... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3139244 Mon, 04 Jan 2010 15:09:04 +0100 3139244 http://www.medworm.com/index.php?rid=3126477&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2F9F6kjjjpdzY%2F In healthy individuals, the first encounter with a virus leads to a primary antibody response. When an infection occurs with the same or a similar virus, a rapid antibody response occurs that is called the secondary antibody response. Antibodies are critical for preventing many viral infections, including influenza. But reinfection may occur if we encounter the same virus before the primary response is complete. Recently three cases of confirmed infection with 2009 influenza H1N1 were reported in Chile. The first patient had laboratory confirmed infection; treatment with oseltamivir resolved symptoms after 48 hours. Twenty days later the patient developed a second bout of laboratory confirmed influenza which was treated with amantadine. The second patient acquired laboratory confirmed i... virology blog blogs http://www.medworm.com/rss/comments.php?id=3126477 Mon, 28 Dec 2009 21:09:44 +0100 3126477 http://www.medworm.com/index.php?rid=3123415&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FNolJ6_Tk678%2F FDA Approves A High Dose Seasonal Influenza Vaccine Specifically Intended for People Ages 65 and Older Accelerated approval process used in vaccine approval Press Release The U.S. Food and Drug Administration approved Fluzone High-Dose, an inactivated influenza virus vaccine for people ages 65 years and older to prevent disease caused by influenza virus subtypes A and B. People in this age group are at highest risk for seasonal influenza complications, which may result in hospitalization and death. Annual vaccination remains the best protection from influenza, particularly for people 65 and older. Fluzone High-Dose was approved via the accelerated approval pathway. FDA’s accelerated approval pathway helps safe and effective medical products for serious or life-threatening diseases beco... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=3123415 Sun, 27 Dec 2009 13:20:39 +0100 3123415 http://www.medworm.com/index.php?rid=3078960&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FjEBJUSa75y0%2F Before the development of cell culture, many viruses were propagated in embryonated chicken eggs. Today this method is most commonly used for growth of influenza virus. The excellent yield of virus from chicken eggs has led to their widespread use in research laboratories and for vaccine production. In fact the vast majority of influenza vaccines – both inactivated and infectious – are produced in chicken eggs. How is influenza virus propagated in eggs? The illustration below shows a cutaway view of an embryonated chicken egg. The different routes of inoculation into the egg are shown, as well as the different compartments in which viruses replicate. For propagation of influenza virus, pathogen-free eggs are used 11-12 days after fertilization. The egg is placed in front of a ... virology blog blogs http://www.medworm.com/rss/comments.php?id=3078960 Thu, 10 Dec 2009 20:51:51 +0100 3078960 http://www.medworm.com/index.php?rid=3066736&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2Fmi1H3VMeQDU%2F If you have been reading this blog you know I believe that those who write about viruses must always make sure that they get the science right. I’m always on the lookout for violations. Are there any problems with the plush toys produced by Giant Microbes? I came across the influenza plush toy in my desk this weekend. The color – green – and the two eyes are gratuitous additions that have nothing to do with reality. Of course, virus particles are too small to have color, but a colorless – or eyeless – toy line would have little appeal to children. What about that elongated shape? Influenza virions are pleomorphic; they are generally spherical, but filamentous particles are often observed in fresh clinical isolates. So the shape is acceptable. But the soft velv... virology blog blogs http://www.medworm.com/rss/comments.php?id=3066736 Mon, 07 Dec 2009 22:19:43 +0100 3066736 http://www.medworm.com/index.php?rid=3059364&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FnChi-DNuUM4%2F When will the 2009 swine-origin influenza virus become a seasonal strain? While prediction is very hard, especially of the future (at least according to Yogi Berra), examining past pandemics can be informative. The 1968 pandemic began with the emergence of a novel H3N2 influenza virus in Hong Kong in July 1968. First isolates (stars) were obtained globally throughout the summer. The previous seasonal H2N2 strain was last isolated in August 1968 in Australia and was subsequently not seen again. There were sporadic H3N2 outbreaks for several months (hatched lines). Epidemic spread (solid lines) ensued in the northern hemisphere throughout the winter, and then ceased in the spring of 1969. In the southern hemisphere the first epidemic occurred from January through October. There were second ... virology blog blogs http://www.medworm.com/rss/comments.php?id=3059364 Fri, 04 Dec 2009 22:17:32 +0100 3059364 http://www.medworm.com/index.php?rid=3056284&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Fwww.virology.ws%2FCUvaccines2009.mov Today I lectured on viral vaccines in the Immunology course at the Morningside Heights campus of Columbia University. I used poliovirus and influenza virus vaccines to illustrate general principles of immunization. My thanks to the engaged students who asked excellent questions! Here is a video of my lecture. Thanks to ScreenFlow, I was able to record my audio along with the slides and post it here the same day. Next semester I’ll be teaching a new undergraduate virology course at Columbia University, and I plan to upload similar videos of each lecture – 26 in all. I’ll post more information here about that course in early 2010. Download ‘Vaccines’ video. 67 MB .mov video file 247 MB .wmv video file (Source: virology blog) virology blog blogs http://www.medworm.com/rss/comments.php?id=3056284 Wed, 02 Dec 2009 23:18:04 +0100 3056284 http://www.medworm.com/index.php?rid=3047871&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FfPQVRzxWswg%2F The New York Times has published an editorial entitled “The Swine Flu, as of Now” which presents their views of the current influenza pandemic. The piece covers the number of infections, hospitalizations, and deaths; the distribution of vaccines, and lists those most at risk for severe disease. It begins with a positive view: So far, the news about swine flu is better than expected. The pandemic may have reached its peak and is heading downward in all regions of the country; weekly deaths from the swine flu have started to decline; the virus remains relatively mild; there seem to be few claims of serious side effects from the vaccine; and despite widespread complaints about shortages, vaccine supplies are steadily building up. The wording suggests that the pandemic is over, but... virology blog blogs http://www.medworm.com/rss/comments.php?id=3047871 Tue, 01 Dec 2009 22:25:35 +0100 3047871 http://www.medworm.com/index.php?rid=3016918&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FUuO7_bq9S78%2F A number of readers have asked when we would have information about the safety of the influenza 2009 H1N1 vaccine. The World Health Organization has just released briefing note #16 “Safety of pandemic vaccines” in which they summarize vaccination information from 16 countries in which 80 million doses of vaccine have been administered. Side effects commonly reported include swelling, redness, or pain at the injection site, which usually resolve soon after vaccination. Fever, headache, fatigue, muscle aches, and a variety of allergic reactions, occurring shortly after vaccine administration, have also been reported less frequently. There have been fewer than ten cases of Guillain-Barre syndrome reported in H1N1 vaccine recipients. These numbers are consistent with normal backgro... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016918 Thu, 19 Nov 2009 16:22:20 +0100 3016918 http://www.medworm.com/index.php?rid=3016919&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2F_cPMuuWH1d0%2F Although the influenza 2009 H1N1 vaccine produced by Novartis, Fluvirin, was previously approved for use in the US, the clinical data supporting its safety and immunogenicity had not been released. The company has now issued a media release containing interim clinical data on the effects of the vaccine in humans. According to the company, testing of the vaccine in 4,080 adult and elderly (>65 years) US individuals has revealed that a half dose (3.75 micrograms) without adjuvant “fulfilled immune response criteria associated with protection”. I assume that the latter statement means that hemagglutination inhibition titers of 1:40 or greater were observed, but this is not explicitly stated.  Current US guidelines for the 2009 H1N1 2009 vaccine stipulate that adolescents, adul... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016919 Wed, 18 Nov 2009 22:08:19 +0100 3016919 http://www.medworm.com/index.php?rid=3016922&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FbhhPsUBNuM4%2F GlaxoSmithKline’s inactivated 2009 influenza H1N1 vaccine has been approved by the US Food & Drug Administration and by Health Canada. This action completes the list of pandemic H1N1 vaccines which I previously summarized for the US and Canada. Influenza A (H1N1) 2009 monovalent vaccine is produced by ID Biomedical Corporation of Quebec, a wholly-owned subsidiary of GlaxoSmithKline. The US package insert can be found here (pdf) and the Canadian package insert here. Dosing recommendations for Canada are listed here. Health Canada has also posted a FAQ on the H1N1 vaccine. The ID Biomedical vaccine is available only in multi-dose vials which contain thimerosal. Each 0.5 ml dose contains 15 micrograms of viral antigen. Other components of the vaccine listed at Health Canada include ... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016922 Mon, 16 Nov 2009 15:24:08 +0100 3016922 http://www.medworm.com/index.php?rid=3016923&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2F5Tc0pJIJEx4%2F We’ve made no secret of our enthusiasm for the vaccine against the 2009 H1N1 influenza virus. To help you find locations near you for obtaining both the seasonal and 2009 H1N1 influenza vaccine, Google has developed a feature for the US called the flu shot finder at www.google.com/flushot. Google notes on their blog that this project is just beginning and information has not yet been received about flu shot clinics for many locations. Many locations that are shown are also out of stock. Google has been working with HHS, the Centers for Disease Control and Prevention (CDC) and state and local health agencies to gather information on flu vaccine locations across the country for both the nasal-spray vaccine and the inactivated vaccine shot. Data for locations of flu vaccine are currentl... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016923 Fri, 13 Nov 2009 21:24:37 +0100 3016923 http://www.medworm.com/index.php?rid=3016926&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FqQsjBjTd9LQ%2F The suggestion that yearly immunization against influenza might make children more susceptible to serious disease during a pandemic has generated some controversy. Does this idea have merit? If you have read “Being older is a good defense against 2009 H1N1 influenza”, you are familiar with the concept of ‘heterosubtypic immunity’. After natural infection with influenza virus, the host produces T and B cells directed against internal proteins of the virions. These viral proteins are more conserved among different strains than the surface glycoproteins HA and NA. Upon infection with a different subtype – which occurs during a pandemic – heterosubtypic immunity could limit virus replication and reduce disease and death. Evidence for heterosubtypic immunity to influenza vir... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016926 Fri, 06 Nov 2009 13:00:22 +0100 3016926 http://www.medworm.com/index.php?rid=3016928&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FexJNtCCiQew%2F Why is the incidence of infection with 2009 H1N1 influenza highest among 5-24 year olds, and lowest in those over 65 years of age? Were the oldsters previously infected with a related influenza virus, or is there another explanation? The sera of individuals born in the early part of the 20th century have antibodies that block infection with the 2009 H1N1 virus.  We also know that antibodies that prevent infection with recently circulating seasonal H1N1 viruses do not react with pandemic H1N1 strains. These findings may partly explain the lower incidence of influenza this year in individuals greater than 65 years of age (illustrated). But other factors might also be responsible for safeguarding the older population. Infection of guinea pigs with a 2007 seasonal H1N1 virus confers some prot... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016928 Mon, 02 Nov 2009 22:30:57 +0100 3016928 http://www.medworm.com/index.php?rid=2943954&cid=t_142092_125_f&fid=34820&url=http%3A%2F%2Fwww.dentalblogs.com%2Farchives%2Fadministrator%2Fcranham-on-swine-flu-and-infection-control%2F This is a personal interest for me since my son was premature and is at high risk for flu and illness. We’re always on top of these things. The Swine Flu has been a little blown out of proportion by the media in my opinion, but whatever strain of flu exists, it’s good for professionals to think at a high level for infection control – from how we wash hands to always wearing gloves to covering surfaces to sterilizing handpieces and lasers. It’s a great time to review these procedures that prevent disease transmission. We don’t need to go crazy, but we need to prioritize infection control. I think staff vaccinations should be a personal decision for each individual, not mandated by the government. For me, I get the vaccine, but I haven’t yet gotten the H1N1 vaccine because it’s... dental blog for dentists about dentistry blogs http://www.medworm.com/rss/comments.php?id=2943954 Thu, 29 Oct 2009 19:27:17 +0100 2943954 http://www.medworm.com/index.php?rid=3016929&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FAxucwQXP7OQ%2F “Do Women Need Such Big Flu Shots?” suggests that we would have more doses of influenza 2009 H1N1 vaccine if we accounted for the biological differences between men and women. The idea is that women generate a stronger antibody response than men, and therefore require less vaccine. Does this idea have scientific support? The opinion is based in part on a study carried out in 2004-05, in which adults were immunized with full (15 micrograms) or half-doses of trivalent inactivated influenza vaccine. This vaccine, made by Aventis Pasteur, contains influenza H3N2, H1N1, and B strains. Serum samples obtained before immunization and 21 days later were assayed for antibody response to each strain of influenza by hemagglutination-inhibtion. I’ve taken the data on geometric mean se... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016929 Wed, 28 Oct 2009 21:14:19 +0100 3016929 http://www.medworm.com/index.php?rid=2934431&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Fwww.quackcast.com%2Fspodcasts%2Ffiles%2Fpodcast_34.mp3 My interminable 2.5 hour commute this morning was made tolerable by listening to the Quackcast #35 from Mark Crislip, “Flu vaccine efficacy and 18 taradiddles”. In this excellent and highly recommended episode, Dr. Crislip addresses the contention that the influenza virus vaccine is worthless. To make it even easier for you to listen to this episode, I’ve embedded the podcast in this post, so you just have to click on the audio player below. I do have one criticism: Dr. Crislip uses the term antibiotics to describe drugs that inhibit viral replication. I recognize that Mark is aware of the proper name for antiviral drugs. To enable meaningful discussions, everyone should know that the terms antibiotic and antiviral have very different meaning. (Source: virology blog) virology blog blogs http://www.medworm.com/rss/comments.php?id=2934431 Tue, 27 Oct 2009 16:17:40 +0100 2934431 http://www.medworm.com/index.php?rid=2923329&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FV7maD4f_5g8%2F A study has found older African Americans are less likely to get a flu shot than are older non-Hispanic whites. It’s not uncommon to hear about differences in certain illnesses and approach to illnesses, depending on race or culture, or even genetics. For example, it’s known that African Americans have a higher risk of developing high blood pressure (hypertension). However, when it’s a behavior, such as avoiding a vaccination, it’s important for the medical community to understand why this is happening. Researchers in Buffalo, NY, looked at the reasons why older African Americans may be reluctant to get a flu shot and they found several factors: Many thought that vaccines provided life-long immunity, not just a few months It wasn’t understood by many that the... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2923329 Fri, 23 Oct 2009 21:16:29 +0100 2923329 http://www.medworm.com/index.php?rid=3016933&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FnP-2UGV1rsc%2F The influenza A (H1N1) 2009 vaccine produced by GlaxoSmithKline has been approved by Canada Health. Here is some information on the vaccine to supplement what I’ve provided about the US counterparts. The Canadian vaccine, called Arepanrix H1N1, is supplied in two parts. One contains inactivated H1N1 influenza virus, and the second consists of AS03 adjuvant (DL-a-tocopherol, squalene, polysorbate 80). Before injection the virus and adjuvant are mixed. The vaccine is provided in 10-dose vials and therefore contains thimerosal. More information on the amounts of these components can be found at the Canada Health website (”Product Information Leaflet Arepanrix™ H1N1 AS03-Adjuvanted H1N1 Pandemic Influenza Vaccine”). Health Canada approved the vaccine based on limited clinic... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016933 Thu, 22 Oct 2009 21:51:19 +0100 3016933 http://www.medworm.com/index.php?rid=3016935&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FaU1wBkg6Y00%2F There have been many interesting responses to my recent post, “Are you receiving the influenza 2009 H1N1 vaccine?” Some individuals have already been immunized or plan to do so shortly. Others are concerned about the safety and efficacy of the monovalent preparations. As pointed out recently in a Nature editorial, “Mass-vaccination campaigns…must take public concerns into account”, and “officials should focus on providing people with the information they need to make good choices for themselves.” Here are some facts about the influenza H1N1 vaccine for those who haven’t yet made up their minds whether or not to be immunized. Four companies are licensed to produce the 2009 H1N1 influenza vaccine for the US – CSL Limited, Novartis Vaccine... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016935 Tue, 20 Oct 2009 12:00:39 +0100 3016935 http://www.medworm.com/index.php?rid=2904582&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Fwww.virology.ws%2Fsciencepodcasters-flu.mp3 Because of concerns about the safety and efficacy of the new vaccine against 2009 H1N1 influenza (”swine flu”) Marc Pelletier, PhD from Futures in Biotech and I teamed up to record a public service announcement to encourage vaccination. This announcement addresses safety and side effects, which are expected to be similar to those from any influenza vaccine. Ginger Campbell MD, an emergency room physician, and host of Brain Science Podcast and Sciencepodcasters.org, was kind enough to add her recommendations to the announcement. I encourage you to listen the the announcement and share it with others. You are welcome to place it on websites, blogs, and podcasts. A copy of the mp3 file can be downloaded here. (Source: virology blog) virology blog blogs http://www.medworm.com/rss/comments.php?id=2904582 Sun, 18 Oct 2009 01:08:59 +0100 2904582 http://www.medworm.com/index.php?rid=3016938&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FNyB9oyXmaoI%2F All the evidence I’ve seen so far points to a poor uptake of the influenza 2009 H1N1 vaccine in the United States. This is not good news – inadequate immunization means more infections and more deaths. A few weeks ago I asked a class of about 50 students in a course on Emerging Infections whether they would receive the 2009 influenza H1N1 vaccine. None of them raised their hands. Yesterday, I taught seven high school biology classes about viruses; I asked each group (about 30 students) if they were going to get immunized. About 5 out of over 200 students said they would. My informal poll may not be indicative of the mood of the entire nation, but there is no doubt that the vaccine is in trouble. You would have to be living in a cave to realize that fear about the 2009 H1N1 vacc... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016938 Wed, 14 Oct 2009 18:53:08 +0100 3016938 http://www.medworm.com/index.php?rid=3016942&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2F9putlidlfbI%2F Here at Columbia University Medical Center, all employees and students may receive, at no charge, influenza vaccine every year. I just went to the lobby of the Milstein Hospital, showed my ID, and received the seasonal influenza vaccine. Here is the proof: As I’ve written before, vaccine records provide interesting information. The medical center administration has clearly printed many of these slips to accommodate those who will be receiving the pandemic H1N1 vaccine in a few weeks. Below ‘Seasonal Influenza Vaccine’, which is checked, is ‘H1N1 Vaccine #1 DOSE’. They have left open the possibility that more than one dose will be required, despite a published study – using CSL vaccine -  that one dose induces protective immunity. The nurse who administ... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016942 Fri, 02 Oct 2009 18:27:28 +0100 3016942 http://www.medworm.com/index.php?rid=2855667&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FmGuXEn8fmQ4%2F If you’ve been waiting for the H1N1 (swine flu) nasal flu vaccine, FluMist, it will be available next week in some parts of the United States, but in limited quantities as this is the first shipment. Different states have different strategies for who will be the first to be vaccinated, either by FluMist or the traditional injection. Some states, such as Illinois want to vaccinate their first responders, while others, such as Alaska, want to vaccinate the preschoolers first. Pennsylvania will be targeting it’s elementary school-age children first. The FluMist isn’t for everyone. Because it contains a weakened live virus, it is not for people with health problems, but for healthy people who are in high risk groups. Those who are chronically ill must wait for the injection, ... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2855667 Fri, 02 Oct 2009 12:08:07 +0100 2855667 http://www.medworm.com/index.php?rid=2846511&cid=t_142092_125_f&fid=34820&url=http%3A%2F%2Fwww.dentalblogs.com%2Farchives%2Fadministrator%2Fmandatory-flu-shots-for-medical-dental-workers%2F There is a drive on for all healthcare workers to receive both seasonal influenza and H1N1 vaccinations. New York is the first state to require all healthcare workers, who have direct patient contact at hospitals, hospices, health centers or even home care, to get flu shots – both the seasonal flu and the H1N1 when it becomes available in October. The logic used here is based on the fact that traditionally only about 50 percent of all healthcare are vaccinated during a normal flu season, even though their patients, obviously have a tendency to be more susceptible to the complications of the flu. Additionally, the Hospital Corporation of America is requiring 120,000 employees to be vaccinated as well as MedStar with 25,000 employees. These required inoculations are being met with resistan... dental blog for dentists about dentistry blogs http://www.medworm.com/rss/comments.php?id=2846511 Wed, 30 Sep 2009 13:01:07 +0100 2846511 http://www.medworm.com/index.php?rid=2851969&cid=t_142092_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FPiFMx9Tdeck%2F Countries all over the world are taking serious steps to stop the swine flu pandemic. China began its mass vaccination last week. And by October 5, the United States will distribute the first wave of swine flu vaccines, good for 6 million to million people. But the swiftness of government health agencies and the World Health Organization to address this issue is evidence about how rapid the H1N1 influenza virus has spread. It bears repeating that we need to take precautions in protecting ourselves and our families against the H1N1. What symptoms do you look for in swine flu? The symptoms of swine flu are similar to regular season flu, so report to your doctor if you have any symptoms. You will not know just from the symptoms what kind of flu you have. I know it can seem very confusing wit... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2851969 Tue, 29 Sep 2009 05:54:05 +0100 2851969 http://www.medworm.com/index.php?rid=2842704&cid=t_142092_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FPiFMx9Tdeck%2F Countries all over the world are taking serious steps to stop the swine flu pandemic. China began its mass vaccination last week. And by October 5, the United States will distribute the first wave of swine flu vaccines, good for 6 million to million people. But the swiftness of government health agencies and the World Health Organization to address this issue is evidence about how rapid the H1N1 influenza virus has spread. It bears repeating that we need to take precautions in protecting ourselves and our families against the H1N1. What symptoms do you look for in swine flu? The symptoms of swine flu are similar to regular season flu, so report to your doctor if you have any symptoms. You will not know just from the symptoms what kind of flu you have. I know it can seem very confusing w... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2842704 Tue, 29 Sep 2009 05:54:05 +0100 2842704 http://www.medworm.com/index.php?rid=2839010&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FaKtNJyoYU7I%2F Mark your calendars for November 5th. That’s the day that vaccines for the H1N1 virus are set to arrive in the U.S. The first shipments will go out to doctors and clinics based on a list provided from each state. The first shipment will include the nasal vaccine and then move on to the injectable variety. According to USA Today, four million doses of injectable vaccine are due in the initial run “with another 10 million to 20 million doses due weekly.” In other words, they shouldn’t run out. So be sure to get your shot. Image: sxc.hu. Post from: Blisstree Flu Vaccines to Arrive November 5th (Source: A Hearty Life) A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2839010 Sun, 27 Sep 2009 23:18:00 +0100 2839010 http://www.medworm.com/index.php?rid=2836243&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FIvTKlUdNWag%2F The H1N1 virus may have spread very quickly and remains a serious disease, but there is some good news at least. The disease has remained stable, and has not changed its genetic makeup. This is positive news for health officials, because that means the vaccines that are being created will likely curb the spread of H1N1. Health officials warn, however, that even though the H1N1 virus has maintained its composition, it doesn’t mean that it is any less serious of a disease. It can still put you in the hospital and in some cases, can kill. But with the vaccine hopefully these instances will be much fewer. Image: sxc.hu. Post from: Blisstree Good News: H1N1 Has Not Genetically Changed (Source: A Hearty Life) A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2836243 Sat, 26 Sep 2009 20:38:34 +0100 2836243 http://www.medworm.com/index.php?rid=2834388&cid=t_142092_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FBy_CVnLcEg0%2F The CDC has just announced that the first wave of swine flu vaccines will be available as early as October 5, a full month earlier than first reported. The supply will be good for 6 million to 7 million people, but the government expects about 250 million doses will be available over time. Of course, first priority goes to the most vulnerable, including healthcare workers, children, young adults and pregnant women. But don’t forget that you should still get a separate vaccine for the seasonal influenza. Neither one is going to protect you from the other virus. Now of the groups that the CDC highly recommends to get protection from the seasonal influenza virus, young adults were added on the list to get the swine flu shot. Don’t find this so strange. Even though this age group general... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2834388 Fri, 25 Sep 2009 20:51:36 +0100 2834388 http://www.medworm.com/index.php?rid=2824344&cid=t_142092_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FrErGt51pNKM%2F With 1.3 billion people inside its borders, China seeks to curtail what could be a massive infection of the H1N1 virus later this winter by a mass immunization campaign this week. About 39,000 residents in Beijing had been inoculated with A/H1N1 flu vaccine by Tuesday afternoon, with 14 cases of adverse reaction, an epidemic control expert said here Wednesday. The number of inoculated residents may be small compared to the total population, but China is gaining praise for being the first country to issue such a campaign, and acting as fast as it did. The Sinovac H1N1 vaccine was approved only on September 3rd, and already 40,000 residents have been vaccinated by this Tuesday afternoon. China has also gained reputation as having the most vigilant response against the swine flu pandemic.... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2824344 Wed, 23 Sep 2009 08:48:39 +0100 2824344 http://www.medworm.com/index.php?rid=2812262&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Fwww.twiv.tv%2FTWiV050.mp3 Hosts: Vincent Racaniello and Jason Rodriguez On episode #50 of the podcast “This Week in Virology”, Vincent and Jason review influenza 2009 H1N1 vaccine trials and protection against the virus conferred by the 1976 swine flu vaccine, then move on to a virus called XMRV and its possible role in prostate cancer. Download TWiV #50 (54 MB .mp3, 74 minutes) Subscribe to TWiV in iTunes, by the RSS feed, or by email Links for this episode: One dose of influenza 2009 H1N1 vaccine without adjuvant is enough Partially completed study on influenza 2009 H1N1 vaccine with MF59 adjuvant 1976 swine flu vaccine induces cross-reactive antibodies against influenza 2009 H1N1 strain Explanation of hemagglutination-inhibition and microneutralization assays FDA approves influenza 2009 H1N1 vaccine... virology blog blogs http://www.medworm.com/rss/comments.php?id=2812262 Sun, 20 Sep 2009 14:04:12 +0100 2812262 http://www.medworm.com/index.php?rid=2807795&cid=t_142092_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FXmpN4NVCu0U%2F Finally, we will have protection against the spreading H1N1 influenza! The Foods and Drug Administration just approved four vaccines against the swine flu virus and it looks like the vaccines will be available in a little over a month. Swine Flu H1N1 Vaccine Soon Available Clinical trials proved that the vaccines are safe and only one shot is needed to gain immunity against the virus, and that’s really great news. Most vaccines work best when, and after the booster shot is given so this means that the swine flu vaccine works more quickly than other flu vaccines. So remember, if you’re one of the following people that are in higher priority to be immunized, ask your doctor or pediatrician about its availability. I already told my doctors to call us as soon they have the vaccine so I can... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2807795 Fri, 18 Sep 2009 13:16:01 +0100 2807795 http://www.medworm.com/index.php?rid=2804064&cid=t_142092_117_f&fid=38158&url=http%3A%2F%2Fwww.drneedles.comhttp%3A%2F%2Famericanacupuncture.blogspot.com%2F2009%2F09%2Fh1n1-swine-flu-vaccine.html As a medical physician for over 50 years, I strive to give you the best medical information on controversial medical subjects and let you, the reader, come to your own conclusions. I have no ties to any organization, pharmaceutical, or lobby group. As an practicing medical acupuncturist since 1982, I find western medicine and medical acupuncture are very complimentary that results in astounding healing in pain management, addictions to cigarettes and food, and a host of other maladies. Let me know how we are doing. Your constructive comments are always appreciated. Click the RSS post button on the upper right hand corner if you would like to receive by email our future medical blogs.Visit http://www.americanacupuncture.com/ for more detailed information on healing.THE H1N1 SWINE FLU VACCIN... Dr. Needles Medical Blogs blogs http://www.medworm.com/rss/comments.php?id=2804064 Wed, 16 Sep 2009 20:41:00 +0100 2804064 http://www.medworm.com/index.php?rid=2800495&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FAI8WuyYGRGk%2F FDA Approves Vaccines for 2009 H1N1 Influenza Virus Approval Provides Important Tool to Fight Pandemic The U.S. Food and Drug Administration announced today that it has approved four vaccines against the 2009 H1N1 influenza virus. The vaccines will be distributed nationally after the initial lots become available, which is expected within the next four weeks. “Today’s approval is good news for our nation’s response to the 2009 H1N1 influenza virus,” said Commissioner of Food and Drugs Margaret A. Hamburg, M.D. “This vaccine will help protect individuals from serious illness and death from influenza.” The vaccines are made by CSL Limited, MedImmune LLC, Novartis Vaccines and Diagnostics Limited, and sanofi pasteur Inc. All four firms manufacture the H1N1 vaccines usin... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2800495 Wed, 16 Sep 2009 01:36:04 +0100 2800495 http://www.medworm.com/index.php?rid=3016948&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2F2seSIAybp2o%2F Would influenza virus be the same pathogen if it could not undergo reassortment of its segmented RNA genome? This is the question being asked in the wake of the development of a method to prevent the free assortment of influenza viral RNAs. The process of influenza virus replication includes the incorporation of eight viral RNAs into each newly synthesized virion. This process, called packaging, depends upon specific RNA sequences in each genome segment. By swapping the packaging sequences for the nonstructural protein (NS) and HA genes, a virus was produced which replicated but lost the ability to independently reassort the HA or NS gene. The authors note that the other influenza A virus RNA segments could be modified in a similar way to reduce or eliminate their ability to form reassorta... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016948 Tue, 15 Sep 2009 12:00:10 +0100 3016948 http://www.medworm.com/index.php?rid=3016950&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FMeR-H0aFsuQ%2F An Australian group has reported results of a clinical trial to determine the safety and immunogenicity of a 2009 pandemic H1N1 influenza virus vaccine. Twenty-one days after the first of two scheduled doses, the vaccine proved to be immunogenic in adults. This is good news, as many had believed that two doses of the vaccine would be needed to achieve adequate protective immune responses. A total of 240 individuals were enrolled in the trial and given 15 or 30 microgram doses of an inactivated, H1N1 vaccine propagated in eggs by CSL Biotherapies, Parkville, Australia. Anti-influenza antibody titers were measured at enrollment and 21 days after each vaccination, by hemaggultination-inhibition (HI) and microneutralization assays. A single 15-µg or 30-µg dose of the H1N1 vaccine produced a ... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016950 Fri, 11 Sep 2009 02:14:04 +0100 3016950 http://www.medworm.com/index.php?rid=2768542&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FJAeje41exuk%2F This week I had the pleasure of joining Chris Montera and his friends on “EMS Garage”, a weekly podcast for Emergency Medical Services professionals. We discussed basic information about the 2009 pandemic influenza H1N1 strain such as transmission and immunization plans, and what EMS personnel can do to help prevent the spread of infection. It was a pleasure podcasting with this crew – they are engaging and proud of their work. They are the ones who respond to emergencies, so head on over to EMS Garage to find EMS news, ambulance information, information for paramedics and EMTs, education, and just general fun. Listen to episode #51 to learn why Chris called it “Spit Shields UP H1N1″. (Source: virology blog) virology blog blogs http://www.medworm.com/rss/comments.php?id=2768542 Sat, 05 Sep 2009 13:00:23 +0100 2768542 http://www.medworm.com/index.php?rid=2765647&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FLXJa_UWB1Fs%2F The Advisory Committee on Immunization Practices (ACIP) has released its recommendations on the use of influenza A (H1N1) 2009 monovalent vaccine. Here is my summary of the salient points. The report begins with information on who is contracting pandemic 2009 H1N1 influenza. The median age of persons with laboratory-confirmed infections in the United States is 12 years. The highest incidence of infection is among persons aged 5-24 years, and the lowest is in persons over 65 years of age. Similar findings have been reported in other countries. Comparison of the age distribution of hospitalized persons with laboratory-confirmed novel influenza A (H1N1) also shows a striking difference compared with seasonal influenza, as shown in the figure. As we have discussed previously, the reduced susc... virology blog blogs http://www.medworm.com/rss/comments.php?id=2765647 Fri, 04 Sep 2009 11:30:57 +0100 2765647 http://www.medworm.com/index.php?rid=2757384&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FvXxeKrVVsmA%2F There has been a great deal of discussion about the use of adjuvants to improve the immunogenicity of vaccines against the 2009 H1N1 pandemic influenza strain. What effect do these compounds have on the immune response? Adjuvants are compounds added to vaccines that stimulate the immune response. They are often used when the antigen is in short supply, or does not induce a good antibody response. Because the 2009 H1N1 pandemic influenza strains do not replicate well in eggs, it has been suggested that adjuvants be used to ensure that there is sufficient supply of vaccine. A recent study demonstrates very clearly the effect of adjuvants on the immune response. Mice were immunized with egg-produced 2009 H1N1 influenza vaccine with or without the adjuvant MF59. A boost inoculation was given o... virology blog blogs http://www.medworm.com/rss/comments.php?id=2757384 Wed, 02 Sep 2009 03:16:11 +0100 2757384 http://www.medworm.com/index.php?rid=2751979&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FlehVy7pI4yM%2F Several stores and drugstore chains are offering free flu shots for people looking for work and those who are uninsured or low cost shots, making it more affordable for preventative health. CVS will offer 100,000 free seasonal flu shots (approx $3 million value) those who are job hunting. They are also offering low cost vaccinations at no-appointment walk in clinics throughout the United States. Walgreens, which also provides low-cost vaccinations, will provide $1 million worth of vaccinations to those who are unemployed. Although not free, Rite Aid Corp is offering seasonal vaccinations beginning today and Walmart will be starting in mid-September. If you go to this Walmart site, you can put in your zip code to see if a store near you is participating. For Rite Aid’s schedule and... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2751979 Tue, 01 Sep 2009 02:55:43 +0100 2751979 http://www.medworm.com/index.php?rid=2747830&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Fmedia.rawvoice.com%2Fpmn_twiv%2Fwww.twiv.tv%2FTWiV047.mp3 Hosts: Vincent Racaniello and Dick Despommier On episode #47 of the podcast “This Week in Virology”, Vincent and Dick discuss influenza virus-like particle vaccines produced in insect and plant cells, rapid sharing of influenza research, and answer listener questions about cytomegalovirus, viral evolution and symbiosis and much more. Download TWiV #47 (51 MB .mp3, 71 minutes) Subscribe to TWiV in iTunes, by the RSS feed, or by email Links for this episode: A Farm on Every Floor Influenza virus-like particles in insect and plant cells PLoS Currents: Influenza Transmission of 2009 H1N1 influenza virus to turkeys [Thanks Debbie!] Baxter produces Vero cell H1N1 vaccine [Thanks Peter!] Boundaries of Darwinism podcast [Thanks David!] Phages in human intestine: papers one, t... virology blog blogs http://www.medworm.com/rss/comments.php?id=2747830 Sun, 30 Aug 2009 14:57:38 +0100 2747830 http://www.medworm.com/index.php?rid=2737435&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FlGqfipZRMAM%2F Two different influenza vaccines will be available in the fall of 2009. One will be a trivalent preparation comprising seasonal influenza H3N2 and H1N1 strains, plus an influenza B virus strain. A monovalent vaccine will also be available against the 2009 pandemic H1N1 strain. Many readers of virology blog have asked why these four virus strains will not be combined into a single, tetravalent formulation. I posed this question to Dr. Ruben Donis, chief of the molecular virology and vaccines branch at the U.S. Centers for Disease Control and Prevention. Here is his answer. Some of the reasons that make tetravalent influenza vaccine less attractive at this time: Regulatory considerations: there have been no clinical trials with tetravalent influenza vaccines, and there is little time to do... virology blog blogs http://www.medworm.com/rss/comments.php?id=2737435 Wed, 26 Aug 2009 14:27:55 +0100 2737435 http://www.medworm.com/index.php?rid=2726967&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2Fp7SovphIZeY%2F A new type of vaccine against influenza, made with virus-like particles, has been shown to protect ferrets from infection with the 2009 H1N1 swine-origin strain. What is a virus-like particle, and how is it produced? If you have been taking influenza 101, you know that new virus particles are produced in infected cells by budding. During this process, the membrane bulges from the cell and is eventually pinched off to form a free particle. These virus particles contain the viral RNA segments, and an assortment of viral proteins including PA, PB1, PB2, NP, M1, M2, HA, and NA. But not all of those viral proteins are needed to produce an influenza virus particle. When only the viral HA, NA, and M1 proteins are synthesized in cells, particles are released from cells that look very much like in... virology blog blogs http://www.medworm.com/rss/comments.php?id=2726967 Wed, 19 Aug 2009 14:03:47 +0100 2726967 http://www.medworm.com/index.php?rid=2741082&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FLvYl3XSE39M%2F The Centers for Disease Control and Prevention (CDC) would like to know what the public feels about the impending H1N1 influenza vaccination program this fall. The agency plans to conduct ten meetings in different parts of the United States to learn if the public would like a massive vaccination campaign, or a reduced effort. The meetings will take place throughout August in Colorado, Nebraska, Alabama, California, Indiana, Texas, Pennsylvania, Massachusetts, Washington, and New York. You must make an online reservation to attend one of these meetings. Do you think this is a good idea? Does the CDC care what the public thinks about what the size of the vaccine campaign should be, or is this a tactic to calm down a confused and concerned public? I’m interested in learning what the re... virology blog blogs http://www.medworm.com/rss/comments.php?id=2741082 Mon, 03 Aug 2009 20:38:02 +0100 2741082 http://www.medworm.com/index.php?rid=2741084&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FBRdGyNPRH4s%2F A few weeks ago I asked readers to find the errors in the following statement concerning an experimental influenza vaccine produced by Protein Sciences which involves synthesis of the viral HA protein in insect cells. They warned that the virus could mutate during the southern hemisphere’s flu season before returning north in a more lethal form in autumn, in a pattern similar to that seen in the deadly 1918 flu pandemic, which claimed an estimated 20 to 50 million lives around the globe. The CDC (Centers for Disease Control and Prevention) sent us a dead virus, which is perfectly safe, and then we extracted genetic information from that virus. The statement ‘in a pattern similar to that seen in the deadly 1918 flu pandemic’ is wrong. There is no evidence that mutation le... virology blog blogs http://www.medworm.com/rss/comments.php?id=2741084 Thu, 30 Jul 2009 13:00:08 +0100 2741084 http://www.medworm.com/index.php?rid=2653839&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FQ6VClekX2-M%2F In case of emergencies, people often wonder how it’s decided who gets what. In a situation such as the H1N1 pandemic, the question becomes, who gets vaccinated first and if there are limited stores of vaccines, who has priority? The Advisory Committee on Immunization Practices today issued its recommendations and vaccine guidelines for H1N1 vaccine . They target 5 groups: Pregnant women Health care and emergency services personnel Children and young adults to age 24 years Caregivers and caregiver contacts of children under 6 months old Otherwise healthy adults with certain chronic health conditions It’s estimated that these five groups cover half of the American population, about 159 million. However, there could come to pass a situation where there isn’t enough vaccine... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2653839 Wed, 29 Jul 2009 22:06:12 +0100 2653839 http://www.medworm.com/index.php?rid=2741087&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FkmedLUVeABE%2F The antibody response is crucial for preventing many viral infections and may also contribute to resolution of infection. When a vertebrate is infected with a virus, antibodies are produced against many epitopes on multiple virus proteins. A subset of these antibodies can block virus infection by a process that is called neutralization. Antibodies can neutralize viral infectivity in a number of ways, as summarized in the illustration. They may interfere with virion binding to receptors, block uptake into cells, prevent uncoating of the genomes in endosomes, or cause aggregation of virus particles. Many enveloped viruses are lysed when antiviral antibodies and serum complement disrupt membranes. Non-neutralizing antibodies are also produced after viral infection. Such antibodies bind ... virology blog blogs http://www.medworm.com/rss/comments.php?id=2741087 Fri, 24 Jul 2009 13:00:28 +0100 2741087 http://www.medworm.com/index.php?rid=2611124&cid=t_142092_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FY1vjWbXit88%2F A disturbing OpEdNews.com article led me to find out if there was truth to the claim that swine flu vaccination causes a paralyzing muscular disorder. In 1976, concerns about a global pandemic swine flu led the U.S. government on a national vaccination program. After an increasing number of vaccinated persons developed a rare neurological disorder called Guillain-Barre Syndrome, the government stopped the program. Guillain-Barre Syndrome (GBS) is a rare disorder where the body’s immune system attack the nervous system, causing a wide range of symptoms that range from mild tingling sensation to complete paralysis. In most cases the patient completely recovers but there is no known cure for the syndrome. The exact cause of the the syndrome is unknown, but the most common trigger is bact... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2611124 Thu, 16 Jul 2009 20:16:24 +0100 2611124 http://www.medworm.com/index.php?rid=2741106&cid=t_142092_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FcyFQyC8pDX4%2F This week’s pop quiz involves analysis of an AFP news article entitled “US company makes first batch of swine flu vaccine“. The article reports that Protein Sciences has been awarded a contract from the US Department of Health and Human Services to produce a vaccine by synthesizing the viral HA protein in insect cells. Here are two paragraphs from the article: They warned that the virus could mutate during the southern hemisphere’s flu season before returning north in a more lethal form in autumn, in a pattern similar to that seen in the deadly 1918 flu pandemic, which claimed an estimated 20 to 50 million lives around the globe. The CDC (Centers for Disease Control and Prevention) sent us a dead virus, which is perfectly safe, and then we extracted genetic informat... virology blog blogs http://www.medworm.com/rss/comments.php?id=2741106 Wed, 24 Jun 2009 17:42:34 +0100 2741106 http://www.medworm.com/index.php?rid=2447474&cid=t_142092_87_f&fid=36050&url=http%3A%2F%2Fwww.blisstree.com%2Fbreastfeeding123%2Fvaccine-information-from-dr-bob-sears%2F Pediatrician Dr. Bob Sears makes it his business to stay on top of the latest developments and news regarding vaccinations. He is the author of The Vaccine Book: Making the Right Decision for Your Child. He spoke on the topic of vaccines at the La Leche League conference I went to last weekend. Posing with Dr. Bob Sears after his lecture La Leche League conferences are great because children are welcome at the lectures. As I chased my 10-month-old around the back of the room (until she finally fell asleep in the sling as you can see above), I managed to take in a lot of valuable information from the lecture. Dr. Sears discussed the occurrence and severity of various childhood illnesses, how vaccinations have affected the prevalence of those illnesses, toxins in vaccines, delayed and alter... Breastfeeding 1-2-3 blogs http://www.medworm.com/rss/comments.php?id=2447474 Mon, 01 Jun 2009 02:15:47 +0100 2447474 http://www.medworm.com/index.php?rid=2398858&cid=t_142092_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FIVizdA_ax24%2F The World Health Organization (WHO) says that “at least two influenza shots will be needed to protect against both the seasonal form of the disease and the new swine flu.” An advisory group meets May 14th, however, before drug makers will be given the go-ahead to producing a swine flu vaccine. Part of this decision rests in the manufacturers and when they will be ready to make the new virus, officially known as A/H1N1. In just a couple short weeks, the virus has spread to countries including the United States. However, WHO wants to make certain the vaccine for “regular” flu is readily available before any new strains are created. Image: sxc.hu. Share and Enjoy: Post from: Blisstree WHO Says Two Flu Shots Are Necessary (Source: A Hearty Li... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2398858 Fri, 08 May 2009 09:18:23 +0100 2398858 http://www.medworm.com/index.php?rid=1880161&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F420425765%2F Another shiny day here in the nation’s medicine chest. As always, we are getting an early start and readying our ritual cup of stimulation before researching a few interesting items for you. Meanwhile, here are some others to help you get started on your day. Hope all goes well… Bush Signs Anti-Piracy Law (Reuters) Schwarz Pharma To Expand US Plant, Add Jobs (Indianapolis Business Journal) Sanofi-Aventis To Sell Seasonal Flu Vaccine In China (Yahoo/Reuters) Pfizer To Overhaul Packaging In UK (Packaging News) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1880161 Tue, 14 Oct 2008 10:46:57 +0100 1880161 http://www.medworm.com/index.php?rid=1466098&cid=t_142092_97_f&fid=35050&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmaGazette%2F%7E3%2F296835314%2Fflu_vaccine_may_be_impaired_by.html A new study by Dr. Luc B. S. Gelinck from Leiden University Medical Center, the Netherlands found that TNF inhibitors that are used to treat rheumatoid arthritis impairs the immune response to the influenza vaccine and may leave those patients who use the arthritis drugs more vulnerable to catching the flu.The study found that while the flu vaccine was still effective in patients using TNF inhibitors 4 weeks after the vaccination antibodies for the anti-TNF group were lower than for the group not taking the TNF inhibitors. Despite the differences, the study found that the protection rate was high amongst all groups of patients.The researchers concluded that an annual flu shot, as suggested by current guidelines, is the best protection against the flu for everyone including those takin... PharmaGazette blogs http://www.medworm.com/rss/comments.php?id=1466098 Fri, 23 May 2008 16:00:03 +0100 1466098 http://www.medworm.com/index.php?rid=1230301&cid=t_142092_127_f&fid=34828&url=http%3A%2F%2Fdrclouthier.blogspot.com%2F2008%2F02%2Fflu-vaccine-craziness-continued.html This is one of the craziest headlines I have seen in a long time. This would be like me telling my patients that they should take echinacea to strengthen their immune system even though it is completely ineffective for strengthening the immune system. I got a real chuckle out of this article and thought you should get one to. You will also notice that there are no statistics anywhere in the article that support the need for the flu shot in the first place. If you have a lead on some real statistical analysis of the flu vaccines and their effectiveness I would love to see them. (Source: Dr. Steve Clouthier) Dr. Steve Clouthier blogs http://www.medworm.com/rss/comments.php?id=1230301 Thu, 14 Feb 2008 03:39:00 +0100 1230301 http://www.medworm.com/index.php?rid=2879664&cid=t_142092_123_f&fid=39040&url=http%3A%2F%2Fparentingsense.blogspot.com%2F2008%2F02%2Fwhat-to-do-about-flu.html How to Prevent or Deal with the Flu (Influenza)It’s winter, and the cold and flu season has definitely hit! According to the Centers for Disease Control and Prevention (CDC), up to 20% of people get the flu each season and 36,000 people will die from it. The best way to deal with the flu is to prevent it. Once you have it though, there are several ways you can try to get over it more comfortably.Is it a cold or is it the flu?With both the common cold and influenza, you may get a runny nose, cough and fever. With flu, however, the symptoms typically last longer than a week and the fever may run higher (above 102 F, for instance). People also often get body aches with the flu and may be bedridden. Sometimes, having the flu can lead to a more serious illness such as pneumonia.What to do abo... Dr. Shu Says blogs http://www.medworm.com/rss/comments.php?id=2879664 Thu, 07 Feb 2008 16:06:00 +0100 2879664 http://www.medworm.com/index.php?rid=1108785&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F203542386%2F We would love to do so. But that will have to wait for another day. Perhaps, however, you can indulge. Before you do, you may want to peek at a few of these tidbits, which make for wonderful table banter…. Bayer Discontinues Prostate Cancer Drug (Yahoo/AP) Consort Medical Feels The Loss Of Exubera (In-PharmaTechnologist) Novavax Bird Flu Vaccine Shows Promise (Yahoo/AP) Rite-Aid Loss Is Bigger Than Expected (Yahoo/Reuters) Keata Pharma Buys Pfizer’s Ontario Plant (CBC.ca) Romania Sets Sale Price For State-Owned Drugmaker (Reuters) Share / E-mail (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1108785 Thu, 20 Dec 2007 17:57:10 +0100 1108785 http://www.medworm.com/index.php?rid=1085561&cid=t_142092_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F12%2F11%2Fthe-controversy-around-vaccines.html By Dov Michaeli MD, Ph.DSometimes, When I read something extraordinarily egregious or stupid I catch myself shaking my head in disbelief. I even mutter to myself a few choice expletives. Here are 2 items from the New York Times appearing on 2 consecutive days.“ The New Jersey Public Health Council is expected to vote tomorrow on a rule that would require flu vaccines for any child entering day care or preschool. If it is approved, New Jersey would become the first state in the country to impose that mandate. “The flu vaccine is one of four that the council will consider. There is a vaccine that would be given to children entering day care or preschool to protect against pneumonia and two others that would be given to those entering sixth grade: one to guard against meningococca... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=1085561 Tue, 11 Dec 2007 03:39:46 +0100 1085561 http://www.medworm.com/index.php?rid=1046705&cid=t_142092_97_f&fid=35050&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmaGazette%2F%7E3%2F189368392%2Fflu_shots_for_all_in_britain_i.html British Health Secretary Alan Johnson unveiled plans to provide vaccines for the entire population should there ever be a flu pandemic.While announcing that he had signed an agreement to secure enough flu vaccine for the entire country, Johnson stated that a flu pandemic was "one of the most severe risks" that Britain is facing. In the event of an outbreak the vaccine would be developed based on the specific strain.The last flu pandemic struck in 1968 and lead to approximately 80,000 death in Britain and over 1 million death worldwide.A pandemic is a global outbreak of a new influenza virus for which there is no vaccine and for which people have no immunity. The disease spreads quickly from person to person and causes serious illness, even death. It can sweep acros... PharmaGazette blogs http://www.medworm.com/rss/comments.php?id=1046705 Fri, 23 Nov 2007 14:00:20 +0100 1046705 http://www.medworm.com/index.php?rid=979217&cid=t_142092_97_f&fid=35050&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmaGazette%2F%7E3%2F174988547%2Fflumist_now_recommended_for_ch.html The Advisory Committee on Immunization Practices (ACIP) is now recommending that FluMist for children in the 2 to 5 year old bracket. Previously, the nasal spray was only for children over the age of 5.FluMist, by MedImmune, is a nasal spray flu vaccine that is a substitute for the flu vaccine. Approved in 2003 for people between the ages of 5 and 49, the FDA has now approved it for use in children 2 - 5 as well.The Committee did not advocate for FluMist over traditional flu shots but merely approved it as an alternative for children who fear needles. The ACIP also approved that the government extend its coverage to include FluMist. This means those children who are eligible for Medicaid, Native American children, Alaskan Native children and some who don't have insurance will have... PharmaGazette blogs http://www.medworm.com/rss/comments.php?id=979217 Thu, 25 Oct 2007 19:15:01 +0100 979217 http://www.medworm.com/index.php?rid=886292&cid=t_142092_97_f&fid=35050&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmaGazette%2F%7E3%2F159005866%2Ffda_approves_flumist_for_child_1.html MedImmune Inc. announced that the FDA has now approved FluMist™ for use in children as young as 24 months. The expansion in age now allows for FluMist™ to be used on people from ages 2 - 59. FluMIst(TM) is an Intranasal Influenza Virus Vaccine that is approved for immunization against influenza A and B. A study of over 4,000 children between the ages of two and five saw a 54% decrease in cases of the flu in children who received FluMIst™ as opposed to those that received a traditional flu shot. FluMist differs from the traditional flu shot in that it consists of live, weakened viruses that help stimulate an immune response to influenza. Pedro Piedra, M.D., professor, Department of Molecular Virology and Microbiology, and Pediatrics, Baylor College of Medicine said &q... PharmaGazette blogs http://www.medworm.com/rss/comments.php?id=886292 Thu, 20 Sep 2007 13:56:37 +0100 886292 http://www.medworm.com/index.php?rid=817759&cid=t_142092_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F147303691%2F Have Glaxo and Novartis stumbled yet again? That’s the question raised in a look at Protein Sciences, a much smaller company using a DNA technology to develop flu vaccines that may prove faster than the methods being used by its much bigger rivals, Bloomberg News reports. Losing the flu-shot race may be the latest in a series of setbacks for both drugmakers, which are building plants that are part of a $1 billion US initiative to produce millions of inoculations within six months of an outbreak of a deadly flu. But Protein Sciences, with just 40 employees, is close to winning approval for a method that would cut the time at least in half. Novartis is investing $600 million to build a cell-based flu-shot plant in North Carolina, and has won a $221 million US government for clinical t... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=817759 Thu, 23 Aug 2007 12:43:53 +0100 817759