MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'gabitril'. Sat, 03 Sep 2011 03:02:20 +0100 http://www.medworm.com/index.php?rid=3468020&cid=t_204576_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FX2JmApk8MdI%2F Several widely used anticonvulsants, including Pfizer’s Neurontin, may increase the risk of suicide, attempted suicide and violent death in patients taking them for the first time, according to a study in the Journal of the American Medical Association. Compared with Johnson & Johnson’s Topamax (known generically as topiramate), the study found increased suicide risks for new patients using Neurontin (sold generically as gabapentin); GlaxoSmithKline’s Lamictal; Novartis’ Trileptal, or Cephalon’s Gabitril. Researchers also found an increased risk with Abbott Labs’ Depakine and Epilim, which is sold by Sanofi-Aventis. The findings come two years after the FDA required anticonvulsants to carry a warning they double the risk of suicidal thoughts and beh... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3468020 Wed, 14 Apr 2010 12:04:48 +0100 3468020 http://www.medworm.com/index.php?rid=3012449&cid=t_204576_109_f&fid=35671&url=http%3A%2F%2Fwww.anxietyinsights.info%2Fabstract_effects_of_the_gabareuptake_inhibitor_tiagabine_o.htm Discussion: Whereas tiagabine did not show beneficial effects on clinical symptoms in PD compared to placebo, results of challenge experiments suggest effects of TGB on sensitivity to experimentally induced panic. Source... © Georg Thieme Verlag KG Stuttgart   New York (Source: Latest entries from www.anxietyinsights.info) Latest entries from www.anxietyinsights.info blogs http://www.medworm.com/rss/comments.php?id=3012449 Fri, 20 Nov 2009 06:33:00 +0100 3012449 http://www.medworm.com/index.php?rid=1841010&cid=t_204576_109_f&fid=34800&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FClinicalPsychologyAndPsychiatryACloserLook%2F%7E3%2F407457566%2Fgabitril-goes-down.html Gabitril (tiagabine) is an antiseizure medication from Cephalon, which just forked out a cool $425 million to settle charges that it marketed several drugs for unapproved conditions, including Provigil and Gabitril. Government investigators claimed that Gabitril was marketed as a treatment for anxiety, which is too bad considering that it struck out in three clinical trials against a placebo. Each study found no evidence that Gabitril was better than a sugar pill. Gabitril was also allegedly marketed as a treatment for pain. I was unable to locate a single controlled study examining the efficacy of Gabitril for pain, though there were a small number of uncontrolled (i.e., not very useful) studies suggesting that maybe Gabitril could be used to treat pain. Regarding sleep, the placebo-contr... Clinical Psychology and Psychiatry: A Closer Look blogs http://www.medworm.com/rss/comments.php?id=1841010 Tue, 30 Sep 2008 17:14:00 +0100 1841010 http://www.medworm.com/index.php?rid=1841253&cid=t_204576_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F406366468%2F This looks to be the biggest such case involving a biotech. And this involves three - count ‘em, three - drugs that were allegedly marketed for years on an off-label basis in order to greatly widen the potential patient populations, according to court documents. The Cephalon payment includes $375 million in a nationwide Medicaid fraud settlement and $50 million for a corporate criminal plea (here’s the settlement agreement). The drugs in question - Actiq, a “medicated lozenge on a handle” approved only for pain in cancer patients and later linked to some 100 deaths; the Gabitril epilepsy med for adults and children over 12 years, but was pitched as an alternative to Valium and Zanax, and for treating for depression; and Provigil, a narcolepsy med that was promoted f... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1841253 Mon, 29 Sep 2008 15:43:39 +0100 1841253