MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'general interest'. Sat, 03 Sep 2011 02:27:14 +0100 http://www.medworm.com/index.php?rid=5181696&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2Fd2VJaccZ2K0%2F Check it out: Tempest Milky Way from Randy Halverson on Vimeo. And this, with the winter sky in time lapse photography: Sub Zero – winter night timelapse from Randy Halverson on Vimeo. (Source: The Doctor Is In) The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=5181696 Thu, 01 Sep 2011 23:38:38 +0100 5181696 http://www.medworm.com/index.php?rid=4959995&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2FiMBgUWNcbdY%2F Word of my demise, widespread and nefarious as it has been, is most assuredly premature. I must put these scurrilous rumors to rest… But life has been, well, most interesting… The past year or so has been one of the most challenging in many a season, on a number of fronts. Professionally, the passage of Obamacare has made it abundantly clear that the independent private practitioner is a dying breed, and likely will disappear — with the exception of cash-only, concierge-style arrangements — within the next few years. The administrative burden is crushing — unfunded mandates, such as pay-for-performance, compliance programs, HIPAA, mandated “government certified” EMRs (even though existing, non-certified ones are fully functional), and intrusive, ab... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=4959995 Tue, 21 Jun 2011 22:02:32 +0100 4959995 http://www.medworm.com/index.php?rid=3467813&cid=t_96624_109_f&fid=34750&url=http%3A%2F%2Fpsychcentral.com%2Fblog%2Farchives%2F2010%2F04%2F14%2Fsketching-a-more-realistic-portrait-of-science-in-practice%2F One of the most notable developments in the book business in the last decade or so has been the rise of the likes of Malcolm Gladwell (The Tipping Point, Blink, Outliers, etc.), Steven Leavitt, Stephen Dubner (Freakonomics, SuperFreakonomics), Ian Ayres (Super Crunchers), and Nicholas Taleb (Fooled by Randomness, The Black Swan). All of their books are best-sellers; all of them have been embraced as business books, management books, and general interest books. For anyone trained in the sciences, this is a thrilling development, a sure sign that scientific thinking has enthralled the public. This welcome development was an inspiration for writing my new book, titled Numbers Rule Your World: The Hidden Influence of Probability and Statistics on Everything You Do (McGraw-Hill, 2010). As a lon... World of Psychology blogs http://www.medworm.com/rss/comments.php?id=3467813 Wed, 14 Apr 2010 10:02:20 +0100 3467813 http://www.medworm.com/index.php?rid=3339629&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2Ff5DV6a8cuuM%2F I’ve been incommunicado for a while, in no small part for reasons shortly forthcoming. But lest you be left completely high and dry, here’s a little nugget for you. The WSJ has a book review of Son of Hamas which will definitely be on my reading list when it comes out: Mosab Yousef is the son of Sheikh Hassan Yousef, a founder and leader of the Palestinian terrorist group Hamas. Throughout the last decade, from the second Intifada to the current stalemate, he worked alongside his father in the West Bank. During that time the younger Mr. Yousef also secretly embraced Christianity. And as he reveals in his book “Son of Hamas,” out this week, he became one of the top spies for Israel’s internal security arm, the Shin Bet. Matt Kaminski describes the book as follo... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=3339629 Sat, 06 Mar 2010 16:55:43 +0100 3339629 http://www.medworm.com/index.php?rid=3137645&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2010%2F01%2F02%2Fikinase%2F http://appshopper.com/medical/ikinase Posted in General Interest (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=3137645 Sat, 02 Jan 2010 23:51:42 +0100 3137645 http://www.medworm.com/index.php?rid=3120402&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2FC0haS0tnU9I%2F Here’s wishing you all a very blessed a Merry Christmas! Enjoy your family, the great food, and the time off. And be mindful of its meaning: Now in those days a decree went out from Caesar Augustus, that a census be taken of all the inhabited earth. This was the first census taken while Quirinius was governor of Syria. And everyone was on his way to register for the census, each to his own city. Joseph also went up from Galilee, from the city of Nazareth, to Judea, to the city of David which is called Bethlehem, because he was of the house and family of David, in order to register along with Mary, who was engaged to him, and was with child. While they were there, the days were completed for her to give birth. And she gave birth to her firstborn son; and she wrapped Him in cloths, an... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=3120402 Fri, 25 Dec 2009 09:44:08 +0100 3120402 http://www.medworm.com/index.php?rid=3048059&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2FUNBSx1XO1So%2F     You’ll never look at raindrops the same way again. Check it out. (HT: OrthoCath Blog) (Source: The Doctor Is In) The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=3048059 Wed, 02 Dec 2009 01:14:57 +0100 3048059 http://www.medworm.com/index.php?rid=2469938&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2009%2F06%2F09%2Foff-targets%2F Just when you thought this stuff was easy… Turns out: * Gleevec & Nilotinib hit ‘α-carbonic anhydrase‘ (wiki). (not to mention p38ß) * Sorafenib hits P38 (new structure), * GW-5074 (cRaf inhibitor) weakly hits glutamate dehydrogenase (~2uM, new structure, wiki). Posted in General Interest (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=2469938 Wed, 10 Jun 2009 02:26:54 +0100 2469938 http://www.medworm.com/index.php?rid=2442727&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2009%2F05%2F29%2Faurigenes-insights%2F A Big thanks to Aurigene’s [colorblind] scientists who have been gracious enough to share with us this presentation given in India at a recent med-chem conference. Structural Insights into Kinase Inhibition More like this please! Posted in General Interest (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=2442727 Sat, 30 May 2009 01:54:00 +0100 2442727 http://www.medworm.com/index.php?rid=2442728&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2009%2F05%2F25%2Fallosterism-a-diatribe%2F So just what is an allosteric kinase inhibitor? Google’s I’m feelin lucky hit ? (āl’ō-stěr’ĭz’əm) A change in the activity and conformation of an enzyme resulting from the binding of a compound at a site on the enzyme other than the active binding site. Wikipedia? Nothing special. Etymology of the word? The word comes to us via a conjunction of the Greek Allos:”another, else, latter, other, alias, another” & the chemical adjective Steric: “Of or relating to the spatial arrangement of atoms in a molecule;” Further along this theme the chemist will be familiar with the use of the term ’steric’ and recognize that a ’steric interaction’ is one where two atoms or moeities simply cannot occupy the same... KinasePro blogs http://www.medworm.com/rss/comments.php?id=2442728 Mon, 25 May 2009 04:28:33 +0100 2442728 http://www.medworm.com/index.php?rid=2349713&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2009%2F04%2F19%2Faacr-2%2F Send Structures / Will Post! Email me smiles/inchi/chemdraw/iupac - whatever.  Structure and a corporate number is good enough, but any other info - feel free. (please include whether you want to be anon) Posted in General Interest (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=2349713 Mon, 20 Apr 2009 01:56:05 +0100 2349713 http://www.medworm.com/index.php?rid=2268749&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2009%2F03%2F16%2Fits-all-the-rage%2F Kinase-Blogging is rightly where it’s at these day’s MoTD: Got: Sutent? Biohealth Investor: Got Sutent Too. Derek: Wants to know if the field is still hot. OPD: Still makin’em Shaji: Has something to say And Sammy read a paper (though has peculiar taste in music.) to celebrate I’ll be hitting the post button a couple times over the next few days. Posted in General Interest (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=2268749 Mon, 16 Mar 2009 05:26:15 +0100 2268749 http://www.medworm.com/index.php?rid=2027016&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2008%2F12%2Fhello-kitty-hospital.html If I owned my own hospital, all the nurses would have to wear Hello Kitty scrubs. Taiwan beat me to the punch."Describing the objectives of the hospital, (the director) said: "I wish that everyone who comes here, mothers who suffer while giving birth and children who suffer from an illness, can get medical care while seeing these kitties and bring a smile to their faces, helping forget about discomfort and recover faster."Me too, Mr. Tsai. Me too.But my blog genderanalyzer just took a serious beating.via Ace.UPDATE: Not everyone likes the idea, according to Dr. Rob. I think they should have to stay in the Dora the Explorer hospital then. (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=2027016 Wed, 10 Dec 2008 20:10:00 +0100 2027016 http://www.medworm.com/index.php?rid=2017777&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2F477299085%2F   Here’s a collection of archival photographs from Pearl Harbor, Dec 7th 1941. Most were obtained from the naval archives. (more…) (Source: The Doctor Is In) The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=2017777 Sun, 07 Dec 2008 07:38:08 +0100 2017777 http://www.medworm.com/index.php?rid=1939679&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2008%2F11%2F05%2Frational-design%2F ? ~ F(x) has some thoughts. Ever since Captopril, I’ve always thought ‘rational design’ to be over-rated and over-sold.  We can do an awful lot without pin-point accuracy, and frankly we don’t have to understand why something is safe and effective to make it so.  Perhaps Ashutosh has tickled a nerve by bringing it up, but I fail to understand why people prefer this fanciful delusion of rational design to the reality of knowledge-based trial and error, but the primary literature is chock full-o-nuts claiming to be a lot smarter then they really are.  But I digress… On non-oncology indications, of course Fasudil was approved in Japan in 1995 for ‘vascular spasms in the brain’ or some suchness, and is in Ph3 in the US for a few indications.  Pfize... KinasePro blogs http://www.medworm.com/rss/comments.php?id=1939679 Thu, 06 Nov 2008 02:54:46 +0100 1939679 http://www.medworm.com/index.php?rid=1933258&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2F441168806%2F Richard Neuhaus: An Election About the Nature of the Church: American Babylon is our culture. It is not the culture of our choice, although, given the other cultures on offer, it may be the culture we would choose if we had a choice. It is certainly the culture in which we have been chosen and for which we have a measure of responsibility. The irrepressible human aspiration toward the transcendent, toward that which at the core of our being we know to be our destined home, takes many different forms. That aspiration is our religion, whether or not we call it by the name of a religion. The aspiration may be stifled or misplaced, but it cannot be denied; at least it cannot be denied for long. When, as Augustine teaches, our loves and loyalties are rightly ordered, we recognize that the only ... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=1933258 Mon, 03 Nov 2008 17:17:12 +0100 1933258 http://www.medworm.com/index.php?rid=1924704&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2008%2F10%2F31%2Fboo-2%2F Posted in General Interest       (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=1924704 Sat, 01 Nov 2008 03:12:18 +0100 1924704 http://www.medworm.com/index.php?rid=1901963&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2008%2F10%2F23%2Fch-pi%2F Kissei’s done a little math on LCK ligands and suggests the stablization owes to those methyl’s. BMCL Cool, yah ,so, umm, like, thats why they gotta be flat. Posted in General Interest, Lck       (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=1901963 Fri, 24 Oct 2008 12:28:14 +0100 1901963 http://www.medworm.com/index.php?rid=1894947&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2008%2F10%2Fmedical-oddities.html Number 4 - World's largest handOddee is a very interesting site. I'm hooked!Check out the cat bomb. (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=1894947 Wed, 22 Oct 2008 07:47:00 +0100 1894947 http://www.medworm.com/index.php?rid=1880150&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2008%2F10%2F15%2Fucbs-got-a-chart%2F go check it out. Posted in clinical, General Interest       (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=1880150 Thu, 16 Oct 2008 01:20:16 +0100 1880150 http://www.medworm.com/index.php?rid=1825638&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2008%2F09%2Fhow-affirmative-action-damaged-our.html "The mortgage bubble was essentially a bet on the purportedly increased creditworthiness of the bottom half of the American population. After three decades of the home ownership rate stalling at around 64 percent, a series of federal initiatives to increase minority and low-income ownership helped push the rate up to just below 70 percent. The housing bubble ... never made much sense. The lower half of American society, where the new homeowners had to come from, isn’t getting better educated, is not settling down to more stable family structures, and is not developing a more rigorous code of honor about paying debts.Nor was the government doing much of anything to help the bottom half earn more in order to afford home ownership. Indeed, by not enforcing the laws against illegal immigrati... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=1825638 Wed, 24 Sep 2008 07:34:00 +0100 1825638 http://www.medworm.com/index.php?rid=1790308&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2F391880883%2F Charles Gibson’s interview of Sarah Palin is the buzz of the blogs the past few days. In particular, was Charlie’s challenge on her prayer for the troops, taken out of context and misquoted, yet asserted by Gibson to be her “exact words.” He then followed up with the question “Are we fighting a holy war?” Gibson, who has worked hard to maintain his media image as a fatherly, soft-spoken news anchor, was revealed, unsurprisingly, to be quite a partisan. No news there — his questions seemed tailored to echo the Obama campaign message, that she is inexperienced, out of her league in foreign policy, a Bush clone, and a religious extremist. But the real essence of his question about her prayer for the troops was not his mangling of its context, nor his ... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=1790308 Sat, 13 Sep 2008 23:18:14 +0100 1790308 http://www.medworm.com/index.php?rid=1764213&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2008%2F09%2F05%2Fbest-of-kp%2F In case you came late to the party, here’s some of my favorites: The Kinaverse Approved Kinase Inhibitors Ph3 Kinase inhibitors S—-O Cl—-O Note the RSS feed of my reading list. Also note comments are closed - email me if you’ve got something to say, or start your own blog.  Go on - Its fun. (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=1764213 Fri, 05 Sep 2008 04:10:42 +0100 1764213 http://www.medworm.com/index.php?rid=1720546&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2008%2F08%2F20%2Fat-least-its-free%2F The new ‘Perspective‘: Some useful information bracketed by useless commentary. Affinity is not even a check-box on the road to an approved drug.  What’s stopping 99.9% of real compounds coming from real programs isn’t potency.  This makes a discussion of how many hydrogen bonds to the hinge are in approved drugs totally irrelevant. Fact Check: >> Ruboxistaurin is not an approved drug. >> Fasudil is only approved in Japan. >> And you forgot Tasigna (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=1720546 Thu, 21 Aug 2008 01:08:19 +0100 1720546 http://www.medworm.com/index.php?rid=1668697&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2008%2F07%2F30%2Ffirst-jacs-in-how-long%2F 1st   I’m still retired. 2nd  This is the first JACS in about 10 years worth reading: (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=1668697 Thu, 31 Jul 2008 01:35:52 +0100 1668697 http://www.medworm.com/index.php?rid=1522085&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2008%2F06%2Fdreaded-hand-tissue.html An unfortunately common practice around these parts is for patients to hold onto a Kleenex for a prolonged period of time. Not a thin, billowy pristine one fresh out of the box, nor one carefully folded for convenient storage just in case it's required. No, I'm talking about the dreaded hand tissue, molded into a crusty tubular shape by the combination of absorbing various bodily secretions and applying what's left of Grandma's grip strength.Now I don't know about you, but when I'm done with a Kleenex I throw it away immediately. The sole purpose of such tissue is to use it to collect stuff that you don't want to get on your hands. Otherwise you'd just blow your nose in your hand and wipe it on your jeans, right? These patients missed that memo, it seems. They clandestinely hold onto their... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=1522085 Mon, 16 Jun 2008 05:26:00 +0100 1522085 http://www.medworm.com/index.php?rid=1501441&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2F307456062%2F Threat of world Aids pandemic among heterosexuals is over, report admits: A quarter of a century after the outbreak of AIDS, the World Health Organization (WHO) has accepted that the threat of a global heterosexual pandemic has disappeared. In the first official admission that the universal prevention strategy promoted by the major Aids organizations may have been misdirected, Kevin de Cock, the head of the WHO’s department of HIV/AIDS said there will be no generalized epidemic of AIDS in the heterosexual population outside Africa. Dr. de Cock, an epidemiologist who has spent much of his career leading the battle against the disease, said understanding of the threat posed by the virus had changed. Whereas once it was seen as a risk to populations everywhere, it was now recognized tha... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=1501441 Sun, 08 Jun 2008 17:34:01 +0100 1501441 http://www.medworm.com/index.php?rid=1446062&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2008%2F05%2Fwhere-i-stand.html OK, I'm hooked. You can look me up under "scalpel." (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=1446062 Thu, 15 May 2008 20:20:00 +0100 1446062 http://www.medworm.com/index.php?rid=1367931&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2F268824839%2F Still trying to stay one step ahead of the snapping alligators, so here’s another older post, hopefully worth your time — Dr. Bob   Damn!, I hate these calls… Lying on my desk, clipped to a yellow manila binder, is a single sheet of paper. Its pleasant color format and sampled photomicrograph belie the gravity of its content: Adenocarcinoma, Gleason grade 9, involving 60% of the specimen. How do you deliver a death sentence? Your first impression of Charlie is his sheer mass: 50 years young, healthy as a horse, built like a tank, a former football player turned popular coach at a local high school. He arrived at my office after seeing his family physician for an acute illness, with fever, chills, and problems urinating. His doctor had diagnosed a urinary tract infec... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=1367931 Sat, 12 Apr 2008 07:05:20 +0100 1367931 http://www.medworm.com/index.php?rid=1340623&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2Fdocisinblog%2FwNlq%2F%7E3%2F261739344%2F   White dogs can’t dance…. On forgiveness & race: An Open Letter to Senator Obama Neuhaus on ‘The Speech’: quietly demolishing Obam Obama Dana: The Strange Ways of Black Folk Watch out for customers with swinging watches: ‘Hypnotist’ thief hunted in Italy Elephants in the living room: QandO on the Medicare and Social Security financial black hole. Let’s expand these programs, shall we? Mug not, lest ye be mugged: A Victim Treats his Mugger to Dinner. Here’s another, somewhat different approach: “And then I kicked him in the teeth”. That’s all for now, God bless, back soon. (Source: The Doctor Is In) The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=1340623 Tue, 01 Apr 2008 05:13:24 +0100 1340623 http://www.medworm.com/index.php?rid=1229243&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2008%2F02%2Fwhat-is-torture.html There's a very interesting but somewhat one-sided discussion about the subject over at Sid's place, so I thought I'd bring it over here for my readers to have a go at the topic. Here are my thoughts:Torture is basically putting someone in an uncomfortable situation to try to influence their behavior. The difficulty is drawing the line to decide what is allowed treatment of prisoners and what is not.Is harsh questioning torture? Is a cold room? How cold? What about making someone stand up for a long time in one place? Or listen to music they don't like? Or depriving them of sleep? Heck, so far that sounds like my third year surgery rotation. Our special forces go through much more hostile training than that, although I understand the difference that since it is on a voluntary basis and that... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=1229243 Wed, 13 Feb 2008 19:25:00 +0100 1229243 http://www.medworm.com/index.php?rid=1138085&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2008%2F01%2F7-weird-facts-about-me.html Food Edition1) My favorite snack is raw green bell peppers sprinkled with salt. But I hate the yellow ones. The red ones are OK.2) I eat pickled jalapeño peppers right out of the jar. Trappey's are the best, because they are crunchy, not soggy.3) I love pistachios, cashews, walnuts, pecans, almonds, and especially hazelnuts. But not mixed into brownies or ice cream. Never, ever.4) And I don't really like peanuts at all. But I like Snickers and Reese's Cups.5) And yet peanut butter disgusts me. My little sister used to chase me around the house with it.6) When I work nights, I live off Stouffer's frozen meals. But I don't bring them to work. I only eat before I leave for work and when I get home from work. Swedish meatballs and French bread pizza are my favorites.7) I'm addicted to candy, ... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=1138085 Wed, 09 Jan 2008 06:25:00 +0100 1138085 http://www.medworm.com/index.php?rid=1131936&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2008%2F01%2Fbest-day-ever.html Thank you, Tom Meents. You, sir, are a total badass.While I'm sorry to say that my son is more of a Grave Digger fan, you are personally responsible for making my daughter breathlessly exclaim that this was the best day of her whole life. And for that I am eternally grateful. She'd never been to a Monster Truck event before, but now she's hooked, thanks mostly to you. You were simply amazing.I watched tonight as you repeatedly punished your left front tire (purposefully, I suspect) until it became flat before the entire wheel was finally torn from its axle. When you continued to aggressively execute jumps on only three wheels before finally plowing into the retaining wall to close the show, you gave all of us fans not only our money's worth but a memory that will last forever.Congratulatio... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=1131936 Sun, 06 Jan 2008 08:24:00 +0100 1131936 http://www.medworm.com/index.php?rid=1104335&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F12%2Fperception-of-time.html Why Time Seems to Slow Down in EmergenciesBy Charles Q. Choi, special to LiveScience.com (my new favorite website, but I can't find a direct link to the article, so I reprinted the whole thing)In The Matrix, the hero Neo could dodge bullets because time moved in slow motion for him during battles. Indeed, in the real world, people in danger often feel as if time slowed down for them.This warping of time apparently does not result from the brain speeding up from adrenaline when in danger. Instead, this feeling seems to be an illusion, scientists now find.To see if danger makes people experience time in slow motion, scientists at Baylor College of Medicine in Houston tried scaring volunteers. However, roller coasters and other frightening amusement park rides did not cause enough fear to mak... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=1104335 Wed, 19 Dec 2007 03:53:00 +0100 1104335 http://www.medworm.com/index.php?rid=1087705&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F12%2F11%2Fkinasepro-done%2F Thank you for taking part in this just-over-a-year-long experiment known affectionately industry-wide as: KinasePro. Its been a fun ride, and through the 504 posts, 840 comments, and 400,000 page-views I’ve learned a great deal from all of you. In addition to KinasePro I have a handful of other medicinal chemistry related projects in the works, but frankly keeping this site updated is just getting in the way of getting them done. These endeavors will hit the world-stage in the coming year, so send me an email if you’d like to be updated as they comes of age. So long, and thanks for all the fish. (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=1087705 Tue, 11 Dec 2007 19:13:19 +0100 1087705 http://www.medworm.com/index.php?rid=993375&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F30%2Fboo%2F (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=993375 Wed, 31 Oct 2007 01:44:54 +0100 993375 http://www.medworm.com/index.php?rid=977425&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F25%2Fselective-vs-nonselective%2F There are a handful of ways to visualize selectivity among kinase inhibitors after you’ve had them Profiled. The gold standard has become the Ambit panel:   (from the Nature Biotech paper) A simple chart will get the job done: or a heat map like Amphoras’: If you prefer a reductionist approach you’ve always been able to take it down to a single number with fold shift from its nearest neighbor. And now it looks like there may be a statistically more meaningful number with the recent J Med Chem on applying the Gini Coefficient to kinase inhibitor selectivty. In case you missed it, check out the spreadsheet in the supporting info. (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=977425 Thu, 25 Oct 2007 05:33:01 +0100 977425 http://www.medworm.com/index.php?rid=965329&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F19%2Fweekend-reading%2F Imagine that, a Chem Rev I’m actually going to read? (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=965329 Sat, 20 Oct 2007 03:23:06 +0100 965329 http://www.medworm.com/index.php?rid=962696&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F18%2Fcl-o%2F I am somewhere between faithless and agnostic on the role of through space ‘halogon bonding’, but earlier a reader pointed us towards a review on the subject from within the recent kinase-thematic issue of Current Topics in Medicinal Chemistry. With this as a backdrop, here’s another very interesting structure from SGC: 2VAG is Clk1 bound to a dichloroindole. If it is indeed as potent as has been suggested to me, then I might be moving towards believer status. The animation shows their earlier 1z57 with Hymenialdisine, a somewhat more traditional kinase inhibitor. (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=962696 Fri, 19 Oct 2007 04:17:14 +0100 962696 http://www.medworm.com/index.php?rid=943168&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F10%2Fsteal-this-document%2F You may have noticed the Ro5 tab above. Here’s the spreadsheet. To the best of my knowledge it’s the most complete list of clinical stage kinase inhibitors in existence. There are bound to be errors and omissions though, so while I of course don’t want anything proprietary please send me references and structures as appropriate. I appreciate the help. (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=943168 Thu, 11 Oct 2007 05:36:16 +0100 943168 http://www.medworm.com/index.php?rid=932035&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F10%2Fscientist-creates-artificial-life-form.html This is an exciting and somewhat frightening step in our advancement of knowledge. Quantum scientific breakthroughs can be used for the good of humanity, or they can create inconceivable horrors. And like nuclear fission, this technology will probably do both. But once the box has been opened, you can't close it back."Craig Venter, the controversial DNA researcher involved in the race to decipher the human genetic code, has built a synthetic chromosome out of laboratory chemicals and is poised to announce the creation of the first new artificial life form on Earth.The DNA sequence is based on the bacterium Mycoplasma genitalium which the team pared down to the bare essentials needed to support life, removing a fifth of its genetic make-up. The wholly synthetically reconstructed chromosome,... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=932035 Sat, 06 Oct 2007 12:00:00 +0100 932035 http://www.medworm.com/index.php?rid=932140&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F05%2Fread-anything-good-lately%2F Got any advice for somebody who wants to know everything there is to know about Kinases in Drug Discovery? Here’s all I’ve got: Two reviews: Current Signal Transduction 2007, 67-95 Current Medicinal Chemistry 2006, 1735-1748 A book: (haven’t read it yet) Protein Tyrosine Kinases: From Inhibitors to Useful Drugs Some more books: (that look like I should probably want to read them) Progress in Medicinal Chemistry Progress in Heterocyclic Chemistry And did I mention I have a reading list on my reading list? (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=932140 Sat, 06 Oct 2007 01:37:24 +0100 932140 http://www.medworm.com/index.php?rid=928084&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F04%2Fone-year-in%2F   …and for some peculiar reason people keep on clicking. (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=928084 Fri, 05 Oct 2007 00:49:27 +0100 928084 http://www.medworm.com/index.php?rid=928085&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F04%2Fberkeleytube%2F Among the first to recognize that intellectuals are allowed to use YouTube too… UC Berkeley makes lectures available free: (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=928085 Thu, 04 Oct 2007 23:41:24 +0100 928085 http://www.medworm.com/index.php?rid=919091&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F10%2F01%2Ff-u%2F Ashutosh knows more about Fluorine then you. You Go Now. thx (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=919091 Tue, 02 Oct 2007 02:10:04 +0100 919091 http://www.medworm.com/index.php?rid=848308&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F09%2Fanimals-in-er.html I've been around the block a few times, and I thought I'd seen it all. Until the patient walked into the ER carrying both a small dog and a parrot, that is. Service dogs are nothing new, yet they are still uncommon enough to raise an eyebrow (and a smile).But a service parrot? Interestingly, they have been described.Attention 911 doc.....king me! (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=848308 Fri, 07 Sep 2007 12:07:00 +0100 848308 http://www.medworm.com/index.php?rid=848527&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F09%2F06%2Fasco-07%2F All the virtual meeting stuff is now free: check it out. (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=848527 Fri, 07 Sep 2007 01:36:20 +0100 848527 http://www.medworm.com/index.php?rid=833382&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F08%2Fhearing-loss.html "It's the most common sensory abnormality in the world."A tone that most adults can't hear but kids can.I can't hear the secret tone unless I turn the speakers way up, but it drives my kids crazy. Yeah, it's from last year. I didn't have a blog then. (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=833382 Fri, 31 Aug 2007 12:56:00 +0100 833382 http://www.medworm.com/index.php?rid=822804&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F08%2F25%2Fthe-drug-like-properties-of-clinical-stage-kinase-inhibitors%2F - pretty pictures w/ no data - (more…) (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=822804 Sun, 26 Aug 2007 04:07:50 +0100 822804 http://www.medworm.com/index.php?rid=819667&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F08%2F24%2Frule-of-5%2F (more…) (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=819667 Fri, 24 Aug 2007 04:47:19 +0100 819667 http://www.medworm.com/index.php?rid=815349&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F08%2F21%2Fobligatory-scivee-post%2F looks neet-o (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=815349 Wed, 22 Aug 2007 03:45:01 +0100 815349 http://www.medworm.com/index.php?rid=804513&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F08%2F16%2Fdont-abuse-inventorship-scientist%2F So a guy named Brian Druker wrote this piece on how Gleevec is overpriced, eh? Who is he? Well he appears to have written his own byline in case you hadn’t heard: THE? A quick googlification suggests he has plenty of nice things to say about Brian Druker and his role in Gleevec’s discovery… To his credit he does list Jürg Zimmermann (the named inventor on a series of patents starting with EP564409) as one of the ‘unsung heroes‘ in a history of Gleevec essay. According to Zimmermann the discovery went something like this: etc. ht: spicy ip, via pharmalot (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=804513 Fri, 17 Aug 2007 02:50:32 +0100 804513 http://www.medworm.com/index.php?rid=783892&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F08%2Fset-phasers-tobarf.html New flashlight weapon makes targets throw up."The handheld device (uses) light-emitting diodes to emit super-bright pulses of light at rapidly changing wavelengths, causing disorientation, nausea and even vomiting in whomever it's pointed at."Nice. Teleportation is just around the corner. (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=783892 Tue, 07 Aug 2007 06:06:00 +0100 783892 http://www.medworm.com/index.php?rid=780661&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F08%2Fself-portrait.html As interpreted by the Simpsonizer.h/t 10/10The Simpsons Movie was outstanding, btw. I highly recommend it, and so do my kids. The political commentary was hilarious.Here is a flash game featuring one of the scenes, for those who enjoy such things. If you get past level 12, I'll buy you a dozen donuts. (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=780661 Sun, 05 Aug 2007 21:59:00 +0100 780661 http://www.medworm.com/index.php?rid=769218&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F07%2F31%2Fs-o%2F I thought this was pretty well known, but looking at some recent literature along with Ashutosh, I guess its worth highlighting. The short of it is that if you need it in plane maybe you aughta see what it looks like with a sulfur atom. Dasatinib is one such example where the carbonyl is in plane with a heteroaromatic Sulfur atom, but there are plenty of more where that came from… (more…) (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=769218 Tue, 31 Jul 2007 13:25:06 +0100 769218 http://www.medworm.com/index.php?rid=737681&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F07%2F16%2Fdoes-cdk5%2F For my read, the story is less that MIT CURES PHEAR! and more that, heh - slashdot picked up a kinase related press release - then proceeded to mangle it. Nobody tell Derek. In our study, we employ mice to show that extinction of learned fear depends on counteracting components of a molecular pathway involving the protein kinase Cdk5 MIT Press release; Nature Neuroscience; Falculty page (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=737681 Tue, 17 Jul 2007 01:41:57 +0100 737681 http://www.medworm.com/index.php?rid=728587&cid=t_96624_149_f&fid=35786&url=http%3A%2F%2Fkinasepro.wordpress.com%2F2007%2F07%2F04%2Fhappy-independance-day%2F (Source: KinasePro) KinasePro blogs http://www.medworm.com/rss/comments.php?id=728587 Wed, 04 Jul 2007 12:47:06 +0100 728587 http://www.medworm.com/index.php?rid=675819&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Fdocisinblog.com%2Findex.php%2F2007%2F06%2F10%2Fsunday-suggestions-01%2F One of the features I enjoy on some of my favorite blogs is a periodic summary of interesting things they are reading. After all, if you enjoy reading a blog, and value their thoughts and insights, it makes sense that you might well be interested in the things they find interesting. And so, I will begin an irregular weekly feature regularly on a sporadic basis every seven days or so, or whenever. It’s my hope that both my regular readers will find this enlightening, educational and entertaining. Cool tools I have stumbled across will also be on the docket, as will useful or interesting new sites. And being a narcissist, I will also include some of my own previous posts which are lying in the digital dustbin, blowing off the cobwebs of some prior bloviations for old times’ sake.... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=675819 Sun, 10 Jun 2007 20:27:21 +0100 675819 http://www.medworm.com/index.php?rid=611985&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F05%2Fscamming-scammers.html Nigerian scammers trying to trick foreigners into sending them money are nothing new. You've probably seen their e-mails or at least heard about their schemes. This website is dedicated to turning the tables on these criminals. The participants reveal many examples of incredibly elaborate and hilarious responses to these e-mails, ultimately coaxing several of these scammers into humiliating themselves and spending some of the money they have stolen in ironic role-reversals.One such result is this; a Nigerian scammer reinactment of the famous Monty Python Parrot sketch. It's really pretty funny on it's own merits, but when you consider the context in which it was created, it's terrific. The scambaiter tricked the scammer into creating this video by promising to pay him a large scholarship.T... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=611985 Wed, 16 May 2007 05:27:00 +0100 611985 http://www.medworm.com/index.php?rid=588146&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Fdocisinblog.com%2Findex.php%2F2007%2F05%2F02%2Fducking-hard-questions%2F It’s good to know that science is finally beginning to address larger questions of the meaning of life, rather than wasting time on trivial pursuits such as the origins of the universe. This epiphany came to me upon reading the following news release: WASHINGTON (Reuters) - Several species of ducks have evolved complicated genitals in what appears to be an “arms race” between the sexes, researchers reported on Tuesday. And females may be coming out ahead, said the team of biologists at Yale University in Connecticut and the University of Sheffield in Britain. Their findings not only open a window into a little-studied area of biology, but could help shed light on how evolution works to help both males and females control their own breeding, the researchers said. Patricia ... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=588146 Thu, 03 May 2007 14:04:56 +0100 588146 http://www.medworm.com/index.php?rid=575045&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F04%2Fbig-time.html Thanks to GruntDoc for the referral, Eric Berger, a writer for the Annals of Emergency Medicine kindly included an interview with me in his article on Emergency Medicine bloggers:Inevitably most emergency medicine blogs include descriptions of patients. A doctor will present a case, and make a comment. Often the point is simply to vent—consider this snippet from a screed by the anonymous author of Scalpel or Sword for a patient who got tired of waiting and turned abusive:“Oh, and yelling to the world that you have to go to work at 7:30 a.m. does not buy you any sympathy from the staff or your fellow patients. Are you suggesting that you are more important than these other folks, or that they don’t have to go to work? How insulting. Get your obnoxious (but uninjured) ass back in your ... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=575045 Fri, 27 Apr 2007 20:18:00 +0100 575045 http://www.medworm.com/index.php?rid=554435&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F04%2Ftwo-americas.html There are those of us who cut our own hair, there are many more who pay a nominal fee at Supercuts or some such chain, and there are those who take money from their campaign contributors to pay a Beverly Hills stylist $400 for a haircut. While sitting on a throne getting a pedicure, no doubt.Is it still called a "haircut" if it costs $400? Or is there a fancier name for it? For that much money, he should have gotten a happy ending. (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=554435 Thu, 19 Apr 2007 19:45:00 +0100 554435 http://www.medworm.com/index.php?rid=552990&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F04%2Fmy-new-hobby.html As the latest mass casualty shooting proves once again, if you expect the police to save you from an armed attacker, you are living in a fantasy world. Police officers are useful for investigating the crime after someone is already dead or injured, but they cannot follow you around to protect you from an attack. Your personal protection is your own responsibility. Even when law enforcement officers are on the scene of a violent crime in progress, their tactical protocols often delay them from moving in to assist the victim(s). Violent crime is on the rise, and it is not just crazed lone gunmen causing the trouble. It's a disturbing trend, particularly for those of us who often commute at night.These are my latest two toys: on top, a Smith and Wesson Model 642 (.38 special +P) and on the bo... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=552990 Wed, 18 Apr 2007 17:49:00 +0100 552990 http://www.medworm.com/index.php?rid=528858&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F04%2Fmeteor-collision-averted.html This is a cute video. I consider global warming loonies to be just as histrionically ridiculous as meteor-fearers, btw. But this is a novel answer to the meteor problem, at least. It's only a one minute video, so watch it. Even the most fervent and humorless doomsday scenario devotees amongst you will crack a smile at least. I promise.Meanwhile, despite the impending doom of global warming, there was still snowfall at President Bush's ranch in Crawford, Texas yesterday. In April. Brrrr. Guess I shouldn't have packed away my winter coat. (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=528858 Sun, 08 Apr 2007 07:32:00 +0100 528858 http://www.medworm.com/index.php?rid=478639&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F03%2Fabout-me-meme.html I've been tagged by Superstenogirl for this latest meme. Here's some juicy personal info even my parents probably don't know about me!Favorites:favorite color: blackfavorite food: fried chickenfavorite drink: nonalcoholic = iced tea; alcoholic = Crown and 7favorite ice cream: Godiva white chocolate raspberryfavorite movie: Forrest Gumpfavorite T.V. show: Houston Astros game; I don't watch anything on TV but sportsfavorite store: Circuit CityLove:who was your first crush: Valerie Bertinelli (One Day at a Time) .do you believe in love at first sight: Of course.how long was your longest relationship: 25 years and counting.where was your first date at: Astroworld. My father drove us; I must have been 14. It didn't go too well.Have you:have you ever gone on a blind date: No.have you ever been... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=478639 Tue, 13 Mar 2007 16:54:00 +0100 478639 http://www.medworm.com/index.php?rid=478623&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2007%2F03%2Fhigh-profile-poisonings.html There have been several interesting and deadly poisonings recently. Recall the disfiguring dioxin poisoning of Ukranian politician Viktor Yushchenko a couple of years ago?Then there was the fatal poisoning last year of former Russian agent Alexander Litvinenko by the rare radioactive isotope polonium-210, one gram of which could kill 50 million people.Now we have two Soviet-born Americans who have been diagnosed with thallium poisoning while visiting Russia. How they may have ingested the poison — a colorless, tasteless substance that can be fatal in doses of as little as one gram — was not clear.Also this week, an expert in Russian intelligence, Paul Joyal, was critically injured when he was shot by two men in his driveway only days after he accused the Russian government of involveme... Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=478623 Wed, 07 Mar 2007 17:28:00 +0100 478623 http://www.medworm.com/index.php?rid=480224&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Fdocisinblog.com%2Findex.php%2F2007%2F02%2F20%2Fdeep-waters-2%2F The following essay was originally posted in June 2005. The story is a true one, although the names have been changed.     They say that hell is hot. Sometimes, though, it is very, very cold. Jim loved Alaska–it had been his home since birth. God’s country: wild, unpredictable, spectacular in beauty–there was no place like it on earth. Cities were a necessary evil, with their services and surliness, but out in the wild was where life could be found. Out among the glaciers, the ragged mountains framing the endless blue sky like jagged, broken glass, out where grizzlies snatched salmon from raging rapids, shortening their march to death as they fought wild currents to reach their spawning grounds. Out where eagles graced the sky, soaring above green fir spires and... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=480224 Wed, 21 Feb 2007 06:40:45 +0100 480224 http://www.medworm.com/index.php?rid=480225&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Fdocisinblog.com%2Findex.php%2F2007%2F02%2F11%2Fancient-boundaries-2%2F This is a series on the erosion of moral, cultural, and ethical boundaries in modern society:    ♦ Part 1 — Moving the Ancient Boundaries   Do not move the ancient boundary stone set up   by your forefathers.         – Proverbs 22:28 –   The societal trend evident today — the gradual and progressive shift from spirituality and faith-based life principles, to scientific secular rationalism, and ultimately to postmodernism, which is the triumph of tribalism, radical individualism, and emotionalism over faith and reason — has many manifestations. The frantic pace of a society filled with countless pressures and endless distractions permits us at best to focus only on the immed... The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=480225 Sun, 11 Feb 2007 09:10:33 +0100 480225 http://www.medworm.com/index.php?rid=480226&cid=t_96624_85_f&fid=34967&url=http%3A%2F%2Fdocisinblog.com%2Findex.php%2F2007%2F02%2F09%2Fmore-embryonic-stem-cell-info%2F I’ve recently referenced an excellent article on the huge gap between hype and reality with embryonic stem cell research (as opposed to the real and growing applications of adult stem cells), and Michael Fumento again points out the huge gap between myth and reality here (HT: Instapundit). Maybe the word is starting to get out — although I’m not holding my breath. On a separate note, I’ve been quite busy lately, with several personnel changes in the office in the works, but have a few essays near completion on the Faith series (part 1 and part 2 here), Moving the Ancient Boundaries, as well as updates on the Narrows Bridge construction — so stay tuned. God bless, back soon. (Source: The Doctor Is In) The Doctor Is In blogs http://www.medworm.com/rss/comments.php?id=480226 Fri, 09 Feb 2007 14:21:29 +0100 480226 http://www.medworm.com/index.php?rid=478634&cid=t_96624_88_f&fid=34857&url=http%3A%2F%2Fscalpelorsword.blogspot.com%2F2006%2F08%2Fneed-for-speed.html My patient had an intracranial hemorrhage, so I called her personal physician immediately, followed by the Neurosurgeon on call. The Neurosurgeon arrived in just a few minutes, well before the primary doc. She asked me, "how did he beat me here?"I answered, jokingly, "Porsche."I honestly had no idea what type of car the guy drove, I was just trying to be funny. But he looked at me quizzically, and asked "How did you know?"I replied, "If I was a Neurosurgeon, I would drive a Porsche 911 Turbo."Sure enough, that's what he had. Brand new, too. (Source: Scalpel or Sword?) Scalpel or Sword? blogs http://www.medworm.com/rss/comments.php?id=478634 Tue, 08 Aug 2006 11:06:00 +0100 478634