MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'genome project'. Sat, 03 Sep 2011 02:40:55 +0100 http://www.medworm.com/index.php?rid=3463592&cid=t_290186_87_f&fid=38368&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FDisruptiveWomenInHealthCare%2F%7E3%2FyKMxlwsv7PI%2F It’s been awhile since I read a book that has influenced  my thinking.  Maybe it’s because I don’t read as many books for “fun” as I used to.  Maybe it’s because I’ve been pre-occupied with ARRA and HITECH related work or my graduate school course on medical ethics or my teenager’s triumphs and despair as she awaited college acceptance decisions.   But there I was driving in my car listening to a National Public Radio (NPR) segment.  Actually it was Fresh Air with Terry Gross. For the next several minutes I found myself drawn in by an interview with a science journalist named Rebecca Skloot, who wrote a book called “The Immortal Life of Henrietta Lacks.” Now I’ve worked in the health care field for more than 35 years and lived in the Maryland-DC area for... Disruptive Women in Health Care blogs http://www.medworm.com/rss/comments.php?id=3463592 Tue, 13 Apr 2010 12:33:05 +0100 3463592 http://www.medworm.com/index.php?rid=2752088&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FM8OLs7FOhjI%2F Persistence really pays off, and this is especially true in genetic studies. After 35 years of combined research, a father-and-son team has finally identified the source of the gene that causes the heart’s electricity to go awry. For three hundred years, a South African family has been plagued by progressive familial heart block, a disease of the electrical system of the heart. The disease causes an affected person to have irregular heart beats, fainting spells, seizures or sudden death. The risk is greatest soon after birth, during puberty and early twenties and returns in the middle age, and a timely installment of a pacemaker is the best treatment. Using data from the human genome project, Professors Andries and Paul Brink were able to trace the origin of this disease to one man: A... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2752088 Tue, 01 Sep 2009 03:13:01 +0100 2752088 http://www.medworm.com/index.php?rid=2688838&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FjqxKb-XZnKA%2F Thirteen years and US $10 billion later, the first of several human genomes were completely sequenced in 2003 in what is now known as The Human Genome Project. From then on, scientists dreamed of and aimed to get the cost of DNA sequencing down to $1,000 per person. Although the running cost was around $250,000 per genome last year, well, that’s still thousands more expensive than most people can afford. No wonder only seven people have had their DNA fully sequenced! But that could all change from now on. A whole genome has been sequenced for only $50,000. Stanford engineer Stephen R. Quake invented the Heliscope Single Molecule Sequencer and sequenced his own DNA in one week – one short week! – using only three staff personnel, which was much faster and cheaper than first project... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2688838 Tue, 11 Aug 2009 05:06:56 +0100 2688838 http://www.medworm.com/index.php?rid=2683961&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FM32MyPH8T1w%2F Just a short note and congratulations to Dr. Francis Collins for being confirmed as director of the National Institutes of Health. Francis Collins is new NIH director According to the Associated Press, Collins was confirmed by the US Senate yesterday via voice vote (say “aye” or “nay”), so I’d have to say this was an even easier confirmation than Judge Sonia Sotomayor, who took her oath today from Chief Justice Roberts as the first Hispanic justice of the US Supreme Court after a non-event of hearings. Collins is a familiar face and name at the NIH, having been one of the prime-movers of the human genome project as head of the Human Genome Research Institute for 15 years. He also authored the controversial book “The Language of God: A Scientist Presents Evidence for Belief ” ... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2683961 Sun, 09 Aug 2009 01:40:00 +0100 2683961 http://www.medworm.com/index.php?rid=2645476&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FSHq0DHhi37g%2F It looks like Proctor & Gamble scientists have just discovered the secret to youthful skin: it’s in 1,500 genes. Using data from the Human Genome Project, P&G scientists identified some 1,500 genes that are responsible for how skin ages. Of those, up to 700 genes control how skin collects and retains moisture. Genomics has key to keeping skin healthy and young. According to an article in the Daily Mail, there are separate ways that skin ages, and each of these are controlled by their own set of genes: Collagen (the protein that gives skin its structure and strength) degrades. Skin loses its ability to keep it hydrated. Fewer skin cells are produced with time. Wrinkles are produced when the skin becomes more inflamed. Age weakens our skin’s natural defense against free-radicals... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2645476 Tue, 28 Jul 2009 08:01:28 +0100 2645476 http://www.medworm.com/index.php?rid=2452494&cid=t_290186_93_f&fid=36982&url=http%3A%2F%2Fprep4md.blogspot.com%2F2009%2F06%2Fhow-accurate-is-this.html Lecturer explains how humans came to have 46 chromosomes while chimpanzees have 48 and discusses the evolutionary significance of this discvery.Its the first time I hear this argument, so I would like to know what you think of it.Thanks for reading :) ... http://prep4md.blogspot.com/ (Source: My M.D. Journey!) My M.D. Journey! blogs http://www.medworm.com/rss/comments.php?id=2452494 Thu, 04 Jun 2009 00:25:00 +0100 2452494 http://www.medworm.com/index.php?rid=2442308&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2Fw9bjwy5bfkw%2F Francis Collins, one of the major players who cracked the genetic code, is in final talks for taking the helm of the National Institutes of Health, reports the Bloomberg News. As director of the National Human Genome Research Institutes (NHGRI) for 15 years, Collins spearheaded efforts to map the human genetic code. With a lot of help from J. Craig Venter at Celera, the project was completed ahead of schedule in 2003, and opened up a plethora of applications and implications for research into our genetic blueprint. Collins resigned from the NHGRI position last year, in his own words, to have “greater latitude than my current position allows to pursue other potential positions of service without encountering any possible conflicts of interest, whether real or perceived." Post from:... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2442308 Tue, 26 May 2009 20:18:12 +0100 2442308 http://www.medworm.com/index.php?rid=2441375&cid=t_290186_93_f&fid=36982&url=http%3A%2F%2Fprep4md.blogspot.com%2F2009%2F05%2Fgenomics-and-future-of-medicine-francis.html The molecular understanding of disease has transformed the pharmaceutical industry. In the future, one can anticipate an increasing number of new drugs whose derivation depended upon a precise genomic understanding of disease. National Human Genome Research Director Dr. Francis Collins explains how genomics could play a role in medicine by improving public health.Thanks for reading :) ... http://prep4md.blogspot.com/ (Source: My M.D. Journey!) My M.D. Journey! blogs http://www.medworm.com/rss/comments.php?id=2441375 Tue, 26 May 2009 16:37:00 +0100 2441375 http://www.medworm.com/index.php?rid=2150842&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FniC0Uc_RKKA%2F   After describing himself as an “unemployed geneticist”, Francis Collins now reveals that he has been “working night and day” with the White House transition for health and human services with Tom Daschle.  Now that that’s over, he is ready to discuss the progress that personalized medicine needs for it to move forward in a responsible way. Francis Collins, the public face of the human genome research and former director of the National Human Genome Research Institute, spoke to biomedical researchers, biotech execs and policy people at a meeting in Washington DC organized by the Personalized Medicine Coalition. "If we’re serious about preventive medicine, and using personalized genomics to inform that, we’re not going to change the genome," he s... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2150842 Sun, 01 Feb 2009 14:54:00 +0100 2150842 http://www.medworm.com/index.php?rid=2131849&cid=t_290186_93_f&fid=36982&url=http%3A%2F%2Fprep4md.blogspot.com%2F2009%2F01%2Fintroduction-to-genomics.html Genomics is the study of the genomes of organisms. The field includes intensive efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping efforts. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of single genes, their functions and roles, something very common in today's medical and biological research, and a primary focus of molecular biology, does not fall into the definition of genomics, unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.For the United States Environmental Protection Age... My M.D. Journey! blogs http://www.medworm.com/rss/comments.php?id=2131849 Sat, 24 Jan 2009 16:48:00 +0100 2131849 http://www.medworm.com/index.php?rid=2086995&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2Fzo4bcOvHNoQ%2F With the new administration comes a new NIH Director and the name that has been heard most often is none other than Francis Collins, former director of the National Human Genome Research Institute. While with the NHGRI, Collins led the Human Genome Project that has become the foundation for almost every mapping project in the field. He also paved the way to have genetic data become open source and freely available to the wider scientific community. So, is Collins the shoo-in to head the bigger National Institute of Health leadership? When asked, all Collins replied was, “No comment.” What’s your take? Want Collins in or not? Take the poll at Genome Technology. Image: Newscom Tags: francis-collins, human genetics, human-genome-project, national institutes of health, re... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2086995 Thu, 08 Jan 2009 06:36:36 +0100 2086995 http://www.medworm.com/index.php?rid=1889028&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2Fr8fMfElnjtQ%2F It’s the Sunday edition of Genetics and Health so let’s sum up some of the genetic research and news that came up this week. A grand rounds lecture "Molecular Genetics of Colorectal Cancer" by Vincent Yang presents an overview on the role of genes in colorectal carcinoma, and shares initial findings on a cell cycle modulator gene. The NY Times article, "Man Who Helped Set the Stage for Nobel-Winning Work Has Left Science" profiles Dr. Douglas C. Prasher, the scientist who provided the essential piece of evidence that helped the work of Nobel Price Chemistry winners Roger Y. Tsien and Martin Chalfie. You’ll be surprised to find out Dr. Prasher’s latest employment. A "pleasure" gene is behind an obese person’s insatiable desire t... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1889028 Mon, 20 Oct 2008 03:22:05 +0100 1889028 http://www.medworm.com/index.php?rid=944703&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F10%2Finteresting-readers.html Over the last week I have been working on a little personal genome search project. I was contacted by one of my readers to help her find someone to "donate" her genome to. Initially I was surprised to receive such a request. Especially because I have railed against using the genome for a crystal ball.But she was vehement that she wanted to donate her genome. Now I Have to tell you that I was then convinced of her altruism. She didn't know where to turn so we began with the usual suspects Dr Church, Dr Collins, Dr Rothberg, Hodosh. But when we were turned away a window opened.I turns out Dr Venter's Institute is looking to turn out 10k genomes in 10 years. The perfect project.....provided these subjects have appropriate care providers to help out......Since Helix Health is taking patients n... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=944703 Thu, 11 Oct 2007 22:17:00 +0100 944703 http://www.medworm.com/index.php?rid=925496&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F10%2F18-hours-to-vote.html Lots of things have transpired since Sunday. I would like to say first, sorry for no posts since Monday. I was preparing for my presentation at the Connecticut conference for the American College of Physicians. Second, I need more submissions for the Genie this weekend. I will be hosting my second and am looking forward to reviewing some great posts. Third, Navigenics is ready to unleash its technology on some unsuspecting consumers in '08. I know at Helix Health we are ready for the wave of "What does this mean?" "What should I do health wise?" etc.etc. etc.In fact,We just received a call from a wonderful consumer of the so-called SNP market for nutritional supplements. The big problem here is that there are SOME SNPs which actually predict risk for disease. But what do they get for a rep... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=925496 Wed, 03 Oct 2007 20:32:00 +0100 925496 http://www.medworm.com/index.php?rid=894330&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F09%2Fscientists-and-sherpa-urge-caution.html According to a recent post at Medical News Today a new article will be published in Science urging caution with the availability of genomic sequencing. I have commented on it several times and now feel like we are beating a dead horse. Listen, if you want your genome to help you decide what clothes to wear, or perfume, or as a trophy. Then go out and get one. I will never stop you from getting your genome as a novelty. But if you want to use your WHOLE genome to make healthcare decisions.......... Well, you better get a second opinion. The only genetic testing that will work for healthcare has nothing to do with whole genome analysis.......for now. So why get your genome? Because, if you get it once you never have to do it again? Well, you saw how that worked out for the iPHONE right?On a ... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=894330 Sun, 23 Sep 2007 18:03:00 +0100 894330 http://www.medworm.com/index.php?rid=869670&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F09%2Fattorney-general-genetic-counselor-and.html Today my phone blew up. I had five different Venture Capital firms call me to pick my brain about "The New deal with Illumina" as well as "Viability of Microarrays in Pharmaceuticals"I must say thank you to those who called. I look forward to speaking with each of your esteemed groups.That being said......I must say that there is a general consensus of the physician side that the time for whole genome analysis for your health is not now. I agree. An excellent scientist Dr Bettinger over at the Genetic Genealogist posed a great question."What is your opinion on Gap Phase?....." "that inevitably long period of time between (1) the availability of inexpensive whole-genome sequencing, and (2) the point when the medical field produces enough specialists in genetics to handle the work load." Wel... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=869670 Thu, 13 Sep 2007 23:47:00 +0100 869670 http://www.medworm.com/index.php?rid=856908&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F09%2Fgene-genie-and-georges-blog.html First....Gene Genie is up at Cancer Genetics. Thanks to Ramunas who put up an excellent edition!!Second and even more importantly......My excellent Chief of Genetic Counseling brought George Church's blog to my attention. My gosh....His evaluation is right on point. His question is a wonderful one...... Great now we have genomes....so what. How do we get to systems biology? Once we have systems biology on point, we will then have truly personalized medicine. We will be able to manipulate the systems....and physicians will become engineers, systems analysts....So when will we get there? How will we get there? My gut says there are 25 different signalling systems and perhaps four different common pathways....these will corroborate with the 4 humours........ Welcome back Galen and great to se... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=856908 Mon, 10 Sep 2007 01:31:00 +0100 856908 http://www.medworm.com/index.php?rid=844123&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F09%2F1000-genomes-coming-soon.html I have been looking at the genome of Craig Ventner. What Surprises me is that we haven't do this sooner. If you haven't heard the diploid genotype of Craig Ventner is up. And several of my buddy bloggers have posted on it. Blaine posted on it here and has a nice wrap up.From The Canadian site The Globe and MailMost experts predict that routinely reading individual genomes will become a reality within five years as the technology to unravel the six billion chemical units that make up DNA gets faster and cheaper. Kathy Siminovitch, director of genomic medicine at Toronto's Mount Sinai Hospital and the Samuel Lunenfeld Research Institute, noted that the first Human Genome Project rang in at roughly $1-billion (U.S). But with the new generation of "ultra-fast" DNA sequencing machines that have... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=844123 Wed, 05 Sep 2007 23:30:00 +0100 844123 http://www.medworm.com/index.php?rid=821661&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F08%2Fcheck-out-my-colleauge-ogan-gurel-md.html I am sitting on the Phone with the good doctor Ogan Gurel. He is an excellent blogger that always never ceases to amaze me with his posts. From his site"Ogan is chairman of the Aesis Group which provides consulting services in the life sciences and healthcare sectors to clients that have included biopharma/medtech companies, hospitals & health systems, private equity firms, venture capital groups and hedge funds. As a healthcare technology expert and futurist, he has been a frequent conference speaker worldwide, addressing the issue of emerging technologies and their impact on the future of healthcare with particular focus on convergent medical technologies"He was interviewed by INTimeTV. It is an excellent example of how we often forget that there is more than genomics is personalized... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=821661 Fri, 24 Aug 2007 16:47:00 +0100 821661 http://www.medworm.com/index.php?rid=765052&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F07%2Fwhat-good-is-map.html Imagine being stranded on a raft......An object is floating in the water. You paddle hard to get it. Once you do, you realize its a map. Hooray, you can finally find some land. Or can you? There are some significant questions to ask yourself prior to having any utility gained from that map.Can you read the map? I used to be in the Navy. We learned how to read nautical maps. But my father, a retired colonel in the Army, would have no clue where to begin. Imagine someone who had no training......Where are you on that map? If you have no orientation, how could you hope to navigate. Where does the sun rise? Simple question. However, when asked almost 15% of Americans do not know the answer. What is on the land you will be paddling to? If you paddle hard to get there only to find out that there... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=765052 Sun, 29 Jul 2007 15:59:00 +0100 765052 http://www.medworm.com/index.php?rid=687111&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F06%2Fpersonalized-medicine-since-1986.html First I would like to apologize for the lack of postings on interesting topics lately. I am glad that others have picked up my slack. Notably Hsien and Bertalan's interesting posts this week. Or for an in depth post on the politics of health care and the reform movement check out VentureBeatWhat I want to pay attention to today is the question I inevitably get asked when I speak to other physicians. "Is what you say feasible in a 7 minute consult world?" The answer is inevitably NO. I do not feel in my heart of hearts that we will ever be able to practice personalized medicine in a 7 minute consult world.What's needed is a Revolution. We need a place where the patient has access to their records and their physicians 24/7. We need a place where the patient is given the skills to understand ... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=687111 Thu, 14 Jun 2007 02:18:00 +0100 687111 http://www.medworm.com/index.php?rid=687116&cid=t_290186_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2007%2F06%2Fdr-collins-reports-from-front-lines.html In the second of my 3 maybe 4 part post I will detail Dr Collins' report from the Front Lines of the Revolution!First some notable quotes"2007 is going to be a landmark year in Genomics and Medicine""We all have ticking timebombs in our genome, you could guess most of them from family history.........But not all of them""We shall have the major genetic risk factors for common diseases in 2-3 years or less"Without further ado I will break his talk down into sections. Dr Collins', feel free to correct anything in this."Notes From the Front Lines"DNA sequencing is undergoing a revolution. I almost felt that he had been reading The Sherpa prior to giving this lecture. I had commented on 454 recently. On powerpoint he showed the technology behind 454 and Illumina. he did not comment on nanopore... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=687116 Tue, 05 Jun 2007 15:15:00 +0100 687116 http://www.medworm.com/index.php?rid=570138&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F111916095%2F Celebrating the fourth anniversary of the completion of the Human Genome Project. DNA Day 2007 is today! Tags: dna day, genetics, genes, genome, dna, human genome project (Source: Genetics and Health) Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=570138 Wed, 25 Apr 2007 17:52:10 +0100 570138 http://www.medworm.com/index.php?rid=509402&cid=t_290186_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F105251315%2F Dr. Francis Collins, Director of the National Human Genome Research Institute, was on NPR’s Fresh Air today and PZ Myers wasn’t impressed with the strong religious message. He [Francis Collins] claims that science is only valid in investigating nature, and that it is inappropriate for examining ideas beyond nature … which begs the question of whether there is anything beyond nature. We also hear that science and spirit are complementary and different tools, but of course we aren’t told how the tool of spirit is applied to anything. We’re told that the intricacy and complexity of the human genome instills a sense of awe, and that it represents a glimpse of God’s creative genius — again, begging the question. When asked whether it was appropriate for Clinto... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=509402 Thu, 29 Mar 2007 23:22:23 +0100 509402