MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'genomic'. Sat, 03 Sep 2011 02:06:33 +0100 http://www.medworm.com/index.php?rid=4734247&cid=t_239478_112_f&fid=34971&url=http%3A%2F%2Fblog.drmalpani.com%2F2011%2F04%2Fpgd-cgh-is-it-of-any-use.html The newest IVF technology uses a fancy new technique which marries IVF and genetics. This is called PGD ( preimplantation genetic diagnosis) with CGH ( comparative genomic hybridisation) and there are lots of press releases and articles touting this as the newest breakthrough !Doctors , like all big boys, love to play with new toys - and the newer the better ! This is especially true when they have expensive new technological tools, which no other competitor has. Doctors can be very competitive - and are always trying to be one-up on each other. An easy way of being different is to use the newest technology - but the trouble is that never is not always better ( though newer is always more expensive !)Because these new tools are so expensive , doctors need to use them extensively, to justif... The Patient's Doctor blogs http://www.medworm.com/rss/comments.php?id=4734247 Tue, 19 Apr 2011 02:45:00 +0100 4734247 http://www.medworm.com/index.php?rid=3858383&cid=t_239478_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FOMw0S5fJrXc%2F Top of the morning to you. And a sunny one it is. Hope your day is getting off to a good start. As for us, we have the usual laundry list of meetings and deadlines, which calls for a cup of stimulation or three. So please join us as we brace for day ahead. And of course, drop us a line if you hear something interesting. We always enjoy a bit of insight. Meanwhile, have a great day… Gilead May Get FDA Warning Letter (San Francisco Business Journal) Genzyme Will Need An Extra Year To Fix Manufacturing Woes (Bloomberg News) Lilly To Lay Off 500 More Employees (Indianapolis Star) Merck Prostate Cancer Merits More Attention: Study (Bloomberg News) Sanofi Strikes Personalized Medicine Deal With Scripps (PharmaTimes) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3858383 Wed, 11 Aug 2010 11:09:41 +0100 3858383 http://www.medworm.com/index.php?rid=3378671&cid=t_239478_131_f&fid=35743&url=http%3A%2F%2Fthegenesherpa.blogspot.com%2F2010%2F03%2Fmoment-of-clarity-some-dtcg-is-not-bad.html Ok,Here is the G-d's honest truth. Not all SNP/DTCG companies are bad. What do I mean by bad? Not all SNP/DTCG companies misrepresented that which is not medically useful as medically useful.I look at Pathway and Counsyl for example. Fast followers looking to say what they do and mean what they say.Some of these DTCG tests could be clinically relevant and useful. The problem I have, is that there is no point at which I can say, "Hey I just want the clinically relevant stuff!" No ear wax please.I need that as a clinician. If I want a huge panel of say CYP450 tests, where do I go? there are some labs that do this and charge and arm and a leg. One company, who I used charged the patient thousands of dollars because insurance wouldn't pick it up.That cannot ever happen again.With the addition ... Gene Sherpas: Personalized Medicine and You blogs http://www.medworm.com/rss/comments.php?id=3378671 Thu, 18 Mar 2010 12:52:00 +0100 3378671 http://www.medworm.com/index.php?rid=3089211&cid=t_239478_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F15%2Fgovernment-response-to-the-house-of-lords-science-and-technology-committee-inquiry-into-genomic-medicine%2F Title: Government response to the House of Lords Science and Technology Committee Inquiry into Genomic Medicine Skinny: The Government response to the House of Lords Science and Technology CommitteeInquiry into Genomic Medicine . The response reinforces the Governments commitment to genetics research and aims to maintain the UK’s position as a world-leader in associated health research, development and innovation. It clearly sets out how the Government will continue to ensure the NHS is ready for future developments and that new technologies are properly developed and translated into clinical practice Publisher: DH Size of Publication: 35p. Published: 14/12/2009 Posted in Genetics, Grey Literature, NHS Tagged: Genetics, Genomic Medicine, Grey Literature (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3089211 Tue, 15 Dec 2009 14:00:36 +0100 3089211 http://www.medworm.com/index.php?rid=2970207&cid=t_239478_87_f&fid=38368&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FDisruptiveWomenInHealthCare%2F%7E3%2FVbmPZlSqcW4%2F This month, Disruptive Women welcomes Patrick F. Terry, a self-proclaimed “JAD” (Just A Dad), as our Man of the Month. Q: So, where should we start? You have been involved with founding a number of ground breaking biotechnology companies, life science research foundations, trade associations, philanthropic groups, and a whole host of public policy organizations. A: I enjoy thinking ahead and trying to do the next new thing to advance science, biomedical research, and the business of patient-centered health care. I’m very impatient for change. I consider myself an unrepentant insurgent, renegade, and rabble rouser. I think that is the most powerful disruptive technology there is. That’s why I love the Disruptive Women in Health Care Blog. But honestly, everything I do is i... Disruptive Women in Health Care blogs http://www.medworm.com/rss/comments.php?id=2970207 Fri, 06 Nov 2009 19:44:25 +0100 2970207 http://www.medworm.com/index.php?rid=2553000&cid=t_239478_87_f&fid=38368&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FDisruptiveWomenInHealthCare%2F%7E3%2FJvZlJEPNyj8%2F I’ve been tasked with presenting the genetic and rare disease perspective on comparative effectiveness. I’ll dispense with ‘rare’ right away.  If by rare, we mean single gene disorders, then perhaps it is a useful designation. If by rare, we just mean the equivalent of the US definition of orphan disease, i.e., less than 200,000 people in the US, then we should ask a few questions. In the old model of test and drug development, the ‘block buster, body count’, model, rare was a useful designation.  In a system built for BIG, then rare needed a boost.  In the new age of personalized medicine, all conditions are rare. In fact, they are usually an N of 1 after factoring in the myriad of genes involved, epigenetics, environment and so on.  As we enter new... Disruptive Women in Health Care blogs http://www.medworm.com/rss/comments.php?id=2553000 Sun, 28 Jun 2009 19:14:59 +0100 2553000 http://www.medworm.com/index.php?rid=2442310&cid=t_239478_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2Fzy4jy2NE4Io%2F Otherwise known as the Victorian Ape Woman, “Bearded Lady” Julia Pastrana was a circus act in 19th century Europe. Hers was an extremely rare genetic syndrome that baffled and fascinated the public since she was first exhibited by her husband. Pastrana has a genetic syndrome known as hypertrichosis terminalis where straight coarse hair covered her entire face and body, and her teeth and gums were irregular. "Bearded Lady" Julia Pastrana has rare genetic condition. Image: Public Domain New research released Thursday uncovered the exact genetic mutation responsible for  conditions similar to Pastrana’s. Published in the May 12st issue of the American Journal of Human Genetics, the study looked into three large Chinese Han families with autosomal-dominant congenital generali... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2442310 Fri, 22 May 2009 03:41:00 +0100 2442310 http://www.medworm.com/index.php?rid=2390175&cid=t_239478_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FNEmnSTQkrV4%2F Last month I told you about an innovative partnership that brings community healthcare into the 21st century. The Genomic Medicine Institute was launched at Silicon Valley’s El Camino Hospital together with DNA Direct to enable physicians and their patients access to leading-edge genomic services. Physician studying DNA radiograph. Image: Newscom Genomic Medicine Institute was created so that patients can be better directed in their decisions about their medical conditions, especially when it comes to using genetic tests and counseling. For example, when someone finds out she has breast cancer, one of the questions that is asked is will she pass it to her daughter? Should she tell her sisters about it? Should she have mastectomy? Should her daughter have mastectomies? Difficult quest... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2390175 Wed, 06 May 2009 17:42:41 +0100 2390175 http://www.medworm.com/index.php?rid=2349271&cid=t_239478_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FKh3crT2YFwY%2F In recent years, more and more genetic tests and therapies have become available for patients, physicians and the interested individual. But how does one know which tests to take or are appropriate for one’s condition? And what do we do after we have the test results on our hands? Can our physician help us? Image: Newscom This March, the Genomic Medicine Institute was launched at El Camino Hospital in Monterey, California in response to the emerging opportunities and challenges that the genomic era has introduced. El Camino partnered with DNA Direct to become the first community hospital to integrate genomic medical services into its routine healthcare and provide El Camino physicians and their patients with access to leading edge genomic-based technologies. I had the pleasure of talking... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2349271 Mon, 13 Apr 2009 03:40:00 +0100 2349271 http://www.medworm.com/index.php?rid=1908827&cid=t_239478_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FS-mK9MQbTzk%2F Welcome to the 39th edition of Gene Genie, the carnival of clinical genetics and personalized medicine.   Personalized genomics are all over the news lately, so let’s jump right and see what’s going on. Personalized Genetics  The financial troubles of deCODE Genetics continue to grow following the massive layout last March. Eye on DNA touches on the (im)practicality of genetic testing during recessions. Genome Alberta joins the enthusiastic PG crowd when Mike Spear showed his own genetic test results at a student conference. Gene Sherpas take a swipe at 23andMe for allowing genetic data to be used to make medical decision.’ It’s not only personalized genomes that are becoming public. The Daily Scan features Her2 testing errors, a venue where a woma... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1908827 Mon, 27 Oct 2008 05:44:47 +0100 1908827 http://www.medworm.com/index.php?rid=1837917&cid=t_239478_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F405651364%2F This article was published on Highlight HEALTH. Other Articles You May LikeThe Cancer Genome Atlas Reports Molecular Characterization of Brain TumorsFunding of Childhood Cancer, NF Research in JeopardyIndividual Genetics, Coffee Consumption, BRCA1 and Breast CancerThe Trust and Credibility of Healthcare Blogs (Source: Highlight HEALTH) Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1837917 Sun, 28 Sep 2008 20:21:52 +0100 1837917 http://www.medworm.com/index.php?rid=1750129&cid=t_239478_132_f&fid=35028&url=http%3A%2F%2Flurena.vox.com%2Flibrary%2Fpost%2Fdecipher.html%3F_c%3Dfeed-rss The Database of Chromosomal Imbalance and Phenotype in Humans using Ensembl Resources Nigel Carter Morning Session, 2 September (11th MGED Meeting, 1-4 September, 2008) Genomic disorders, e.g. Down's Syndrome (3 copies of chromosome 21). Need gen... Read and post comments | Send to a friend (Source: Systems Biology & Bioinformatics) Systems Biology & Bioinformatics blogs http://www.medworm.com/rss/comments.php?id=1750129 Tue, 02 Sep 2008 09:35:39 +0100 1750129 http://www.medworm.com/index.php?rid=1556680&cid=t_239478_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F322982346%2F This article was published on Highlight HEALTH. Related articlesGenomic Medicine: An Educational Resource from Helix HealthMore Education Decreases the Risk of Death Gene Genie #32 - Googling the GenieNirvana in the Right Hemisphere: A Stroke of InsightChiropractic Adjustments and Artery Dissection: Is Your Neck in Safe Hands? (Source: Highlight HEALTH) Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1556680 Mon, 30 Jun 2008 04:56:07 +0100 1556680 http://www.medworm.com/index.php?rid=1467131&cid=t_239478_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F297549151%2F Conclusion That concludes the 32nd edition of Gene Genie. My thanks to everyone who submitted an article. You can find more information about the carnival as well as the hosting schedule and past editions at the Gene Genie Website. The next edition will be hosted at Neurophilosophy on June 8th. References Google Backs Harvard Scientist’s 100,000-Genome Quest (Update2). Bloomberg.com 2008 Feb 29. Pearson H. Genetics: what is a gene? Nature. 2006 May 25;441(7092):398-401. View abstract Gotlib et al. HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression. Biol Psychiatry. 2008 May 1;63(9):847-51. Epub 2007 Nov 19. View abstract McGowan et al. Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brain. PLoS ... Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1467131 Sun, 25 May 2008 04:01:35 +0100 1467131 http://www.medworm.com/index.php?rid=1452161&cid=t_239478_107_f&fid=36585&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FHighlightHEALTH%2F%7E3%2F293251081%2F This article was published on Highlight HEALTH. Related articlesCancer Research Carnival #7Lack of Health Insurance Increases Risk of Cancer DeathThe Best of Highlight HEALTH 2007 - The Year in ReviewIndividual Genetics, Coffee Consumption, BRCA1 and Breast CancerTreating Cancer with Personalized Medicine (Source: Highlight HEALTH) Highlight HEALTH blogs http://www.medworm.com/rss/comments.php?id=1452161 Mon, 19 May 2008 13:01:35 +0100 1452161 http://www.medworm.com/index.php?rid=965185&cid=t_239478_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F10%2F20%2Fin-praise-of-the-knockout-mouse.html By Dov Michaeli MD, Ph.DTis the season of the Nobel, and we, ordinary mortals, should rejoice. Global warming was acknowledged as real yet again, sneering antediluvian conservatives notwithstanding. The prize for Chemistry was given for discovery of reactions occurring of the surface of solids—which enabled the invention of none other than the iPOD, among others. The prize for Economics was give for something that I really don’t understand, despite my earnest efforts. And the prize for Physiology and Medicine was given for something that sounds straight out of the boxing ring: the knockout mouse. But this is something too important to dismiss with a shrug and rolled eyes. This technology is already giving us something far more important than the iPOD—it’s a huge ste... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=965185 Sat, 20 Oct 2007 05:48:41 +0100 965185 http://www.medworm.com/index.php?rid=852557&cid=t_239478_107_f&fid=35026&url=http%3A%2F%2Fphylogenomics.blogspot.com%2F2007%2F09%2Fretraction-i-was-buzzing-off-about-bees.html Recently I wrote a post about the recent study on bees associated with colony collapse disorder. After receiving a well thought out email from one of the authors on the study I have decided to retract my blog and apologize to the authors of the bee study. I rushed out my blog without really considering the evidence and the data very carefully and accept that I screwed this one up big time. The study is much more complex and comprehensive that I led people to believe. In part this was due to lack of detail in the actual manuscript but alas most of the fault lies with me - in not trying to contact the authors for more detail before mouthing off.So I am giving myself a new award - the genomic jerk award. Hopefully there will be no more recipients.This is from the "Tree of Life" blog ( http://... The Tree of Life blogs http://www.medworm.com/rss/comments.php?id=852557 Sat, 08 Sep 2007 20:07:00 +0100 852557 http://www.medworm.com/index.php?rid=838866&cid=t_239478_107_f&fid=35026&url=http%3A%2F%2Fphylogenomics.blogspot.com%2F2007%2F09%2Fquality-genomic-reporting-award-seeking.html Well, Genome Technology magazine got on my case for being a bit too snarky with my "awards" sayingIf Jonathan Eisen Offers You an Award, You Probably Want to DeclineFair enough. I can be both passive aggressive and just plain aggressive about my opinions on how things should be done out there. And yes I have ended up focusing frequently on the negative (which is the case for both the awards I have begun dishing out here - the Adaptationomics Award and the Overselling Genomics Award). Plus, my giving out the latest award has taken away a bit from what should be an enormous positive vibe for the latest Wolbachia paper by Julie Dunning Hotopp and Jack Werren and colleagues, which is a spectacular piece of science.So I have decided to try and be positive (occasionally) and have created a new a... The Tree of Life blogs http://www.medworm.com/rss/comments.php?id=838866 Tue, 04 Sep 2007 03:07:00 +0100 838866 http://www.medworm.com/index.php?rid=572351&cid=t_239478_131_f&fid=34975&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FThePersonalGenome%2F%7E3%2F112158485%2Fvideo_rep_louis.html Here is Representative Louise Slaughter (D-NY) discussing the importance of GINA on the House floor yesterday: (If you're reading via RSS, you might need to go to my site to view the embedded video) The bill passed in the House 420-3.  If you're curious, the 3 Nays were Representative Jeff Flake (R-AZ), Representative Ed Royce (R-CA), and Representative Ron Paul (R-TX). --H.R. 493, Genetic Information Nondiscrimination Act  (PDF) Full proceedings from the Congressional Record, April 25, 2007, ~20 pages (PDF) (Source: The Personal Genome) The Personal Genome blogs http://www.medworm.com/rss/comments.php?id=572351 Thu, 26 Apr 2007 04:00:00 +0100 572351 http://www.medworm.com/index.php?rid=498767&cid=t_239478_107_f&fid=35009&url=http%3A%2F%2Fsciencesque.wordpress.com%2F2007%2F03%2F23%2Frandom-omim-search-term-of-the-day-instance%2F So, having been let down by the Random Word Genie yesterday, I mustered up some courage and again sought guidance in my journey though the human genome. The Genie revealed unto me that I shall search the OMIM database with the term “instance“. Thus instructed, let’s venture into the vast expanse of the human genome… Again, as with the previous search term “organizer”, the Genie has lead me into familiar territory. The word “instance” brings up not a gene, but rather a syndrome - PRADER-WILLI SYNDROME (PWS). The reason PWS is familiar to me is because Rachel Wevrick in the Department of Medical Genetics at the University of Alberta has centred her lab around genes associated with this disease. I have seen a number of excellent seminars from her and her studen... Sciencesque blogs http://www.medworm.com/rss/comments.php?id=498767 Sat, 24 Mar 2007 17:26:17 +0100 498767 http://www.medworm.com/index.php?rid=497762&cid=t_239478_107_f&fid=35009&url=http%3A%2F%2Fsciencesque.wordpress.com%2F2007%2F03%2F23%2Frandom-omim-search-term-of-the-day-instance%2F So, having been let down by the Random Word Genie yesterday, I mustered up some courage and again sought guidance in my journey though the human genome. The Genie revealed unto me that I shall search the OMIM database with the term “instance“. Thus instructed, let’s venture into the vast expanse of the human genome… Again, as with the previous search term “organizer”, the Genie has lead me into familiar territory. The word “instance” brings up not a gene, but rather a syndrome - PRADER-WILLI SYNDROME (PWS). The reason PWS is familiar to me is because Rachel Wevrick in the Department of Medical Genetics at the University of Alberta has centred her lab around this very interesting disease. I have seen a number of excellent seminars from her and her students ab... Sciencesque blogs http://www.medworm.com/rss/comments.php?id=497762 Sat, 24 Mar 2007 05:23:24 +0100 497762 http://www.medworm.com/index.php?rid=482901&cid=t_239478_131_f&fid=34975&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FThePersonalGenome%2F%7E3%2F102841383%2Fgenes_in_human_.html 18,308 genes according to Carl Zimmer via PANTHER.  As Carl Zimmer notes, the presumed number of genes in the human genome has been steadily declining over the years.  Early estimates were in the 100K range.  For historical perspective, Lee Rowen won the GeneSweep competition back in 2003 for betting that the human genome contained 25,947 genes -- the lowest estimate in the entire competition. (hat tip, Hsien) -- ORNL, How Many Genes in the Human Genome? (Source: The Personal Genome) The Personal Genome blogs http://www.medworm.com/rss/comments.php?id=482901 Mon, 19 Mar 2007 04:00:00 +0100 482901 http://www.medworm.com/index.php?rid=481452&cid=t_239478_131_f&fid=34975&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FThePersonalGenome%2F%7E3%2F101727676%2Fhodosch_to_run_.html The Archon X Prize for Genomics has appointed Marc Hodosh to lead the $10 million competition.  Hodosh is an entrepreneur and tech geek who recently chaired a robotics competition for segway inventor Dean Kamen.The Archon X Prize will be awarded to the first group that can "build a device and use it to sequence 100 human genomes within 10 days or less, with an accuracy of no more than one error in every 100,000 bases sequenced, with sequences accurately covering at least 98% of the genome, and at a recurring cost of no more than $10,000 per genome."  In other words, the winner must be able to sequence 100 human genomes in 10 days for a $1 million.The X Prize Foundation has published a video describing the competition, check it out: <p><p>&a... The Personal Genome blogs http://www.medworm.com/rss/comments.php?id=481452 Wed, 14 Mar 2007 04:00:00 +0100 481452 http://www.medworm.com/index.php?rid=486524&cid=t_239478_131_f&fid=34996&url=http%3A%2F%2Ftalk.genesanddrugs.com%2F2006%2F11%2F27%2Freading-my-mail%2F I was away for Thanksgiving with family in chilly Seattle. I returned to find 174 comments awaiting moderation. Sadly, all 174 were spam, offering me the usual prescription-drugs-without-prescription, Rolex copies, Prada knockoffs, and a heaping helping of pornography (bestiality has been popular lately). This is pretty much par for the course. Whenever I see one of your real, thoughtful comments about something that’s been posted here, my heart soars. I envy some of those other blogs—mostly political—where a single, not-terribly-profound posting can elicit hundreds of comments. Ah well. Pharmacogenetics and genomic medicine are alive and well. See, for example, the Web site for the Guilford Genomic Medicine Initiative. The Guilford project [Guilford is a county in North Carolina] is... Genes & Drugs Blog blogs http://www.medworm.com/rss/comments.php?id=486524 Mon, 27 Nov 2006 19:16:30 +0100 486524