MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'germ cell'. Sat, 03 Sep 2011 02:46:11 +0100 http://www.medworm.com/index.php?rid=4122024&cid=t_416849_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2010%2F10%2F31%2Fgirls-with-stage-i-ovarian-germ-cell-tumors-can-safely-skip-chemotherapy-until-recurrence%2F Researchers from Dana-Farber/Children’s Hospital Cancer Center found that as many as 50 percent of young girls treated for germ-cell ovarian tumors may be safely spared chemotherapy using a “watch and wait” strategy to determine whether follow-up treatment is needed. Researchers from Dana-Farber/Children’s Hospital Cancer Center (DF/CHCC) found that as many as 50 percent of young girls [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=4122024 Sun, 31 Oct 2010 22:23:31 +0100 4122024 http://www.medworm.com/index.php?rid=4074464&cid=t_416849_155_f&fid=39055&url=http%3A%2F%2Fjulesberman.blogspot.com%2F2010%2F10%2Fgerm-cell-tumor-web-page-available.html The recent blog series on germ cell tumors has been packaged into a single web page available at:http://www.julesberman.info/factoids/germcell.htm- © 2010 Jules Berman key words: carcinogenesis, neoplasia, neoplasms, tumor development, tumour development, tumor biology, tumour biology, carcinogenesis (Source: Specified Life) Specified Life blogs http://www.medworm.com/rss/comments.php?id=4074464 Thu, 14 Oct 2010 12:12:00 +0100 4074464 http://www.medworm.com/index.php?rid=4040802&cid=t_416849_155_f&fid=39055&url=http%3A%2F%2Fjulesberman.blogspot.com%2F2010%2F10%2Fgerm-cell-cancers-of-testes-conclusion.html This is the last entry on a series of blogs on germ cell cancers of the testes.I've added forward and backward links for each of the blogs in the series, so you can visit the first blog in the series and click forward or backward through the sequential entries.Basically, in this series, we showed, using the SEER public use data files, that there has been a large increase in the incidence of germ cell cancers of the testis in white non-Hispanic males since the first SEER observation year (1973) up to the most recent data year (2007).Along with the increase in seminomatous germ cell cancers was a lesser but parallel increase in the non-seminomatous germ cell cancers of the testis, when compared in birth cohort populations. The seminomatous and non-seminomatous germ cell cancers, though deriv... Specified Life blogs http://www.medworm.com/rss/comments.php?id=4040802 Thu, 07 Oct 2010 20:38:00 +0100 4040802 http://www.medworm.com/index.php?rid=4036957&cid=t_416849_155_f&fid=39055&url=http%3A%2F%2Fjulesberman.blogspot.com%2F2010%2F10%2Fexplaining-rise-in-testicular-germ-cell.html In yesterday's blog we saw that the rise in testicular cancer rates in white males showed a parallel increase in seminomatous and non-seminomatous germ cell cancers among birth cohorts.What can explain this increase?There is one class of conditions that is overwhelmingly associated with the development of germ cell tumors of the testis: disorders of sex development of the testes.[1] Among the conditions within this general group are testicular dysgenesis, testicular feminization (insensitivity to androgens), and cryptorchidism. Disorders of sex development of the testis raise the incidence of intratubular germ cell neoplasia or of gonadoblastoma, both of which are testicular precancers. As you might expect, along with the observed increase in testicular germ cell cancers in white males, th... Specified Life blogs http://www.medworm.com/rss/comments.php?id=4036957 Wed, 06 Oct 2010 12:31:00 +0100 4036957 http://www.medworm.com/index.php?rid=4036958&cid=t_416849_155_f&fid=39055&url=http%3A%2F%2Fjulesberman.blogspot.com%2F2010%2F10%2Fexplaining-germ-cell-cancer-rates.html In yesterday's blog we explained how the precancer of testicular germ cell tumors, intratubular germ cell neoplasia, gives rise to seminomas (differentiated germinomatous lineage) and non-seminomas (tumors of pluripotent progenitor cells that are not of germ cell lineage).In the first blog of this series on germ cell tumors , we noted that the increase in occurrences of seminomas has outpaced the occurrences of the nonseminomatous germ cell tumors. Here is a graph, produced from the SEER public use data sets, of the crude occurrences of seminoma and non-seminoma testicular germ cell tumors, in white males, since 1973.The light blue bars are the seminomas, and the maroon bars are the non-seminomatous germ cell tumors of the testes. Since 1973, the seminomas increased from a number much lowe... Specified Life blogs http://www.medworm.com/rss/comments.php?id=4036958 Tue, 05 Oct 2010 15:47:00 +0100 4036958 http://www.medworm.com/index.php?rid=4013597&cid=t_416849_155_f&fid=39055&url=http%3A%2F%2Fjulesberman.blogspot.com%2F2010%2F09%2Fnon-seminomatous-germ-cell-tumors.html In yesterday's blog, we examined the enormous increase in the incidence of seminomatous germ cell tumors occurring in white non-Hispanic males.There are two categories of germ cell tumors: seminomatous and non-seminomatous.The seminomatous tumors are tumors composed predominantly of a single cell type, the gonocyte. The non-neoplastic gonocyte would normally produce sperm cell in the testis. Seminomas are permitted to contain a few neoplastic trophoblasts, but otherwise, seminomas are composed of a population of large, round, monomorphic cells. The other type of germ cell tumors is the non-seminomatous tumors, and these tumors are composed of malignant cells resembling those of the pluripotent primitive embryonic (from the early embryo) or extra-embryonic (from the placenta) malignant cell... Specified Life blogs http://www.medworm.com/rss/comments.php?id=4013597 Mon, 27 Sep 2010 19:00:00 +0100 4013597 http://www.medworm.com/index.php?rid=4003451&cid=t_416849_155_f&fid=39055&url=http%3A%2F%2Fjulesberman.blogspot.com%2F2010%2F09%2Fgerm-cell-tumors-problems.html Germ cell tumors are very rare neoplasms that occur most often in young adults and children.For a variety of reasons, which I'll try to explain in the next few blog posts, much of what we think we understand about these tumors is highly confusing and probably wrong.Considering that these are rare tumors, you might accept a certain degree of ignorance, but sometimes the mysteries that surround rare tumors must be solved before we can make any headway understanding the more common tumors.Also, for some strange reason, the incidence of seminomatous germ cell tumors of the testes, in the white population, has been increasing over the past 35 years (at least).Here are the numbers, computed from the SEER (the U.S. National Cancer Institute's Surveillance Epidemiology and End Results) public use ... Specified Life blogs http://www.medworm.com/rss/comments.php?id=4003451 Mon, 27 Sep 2010 12:40:00 +0100 4003451 http://www.medworm.com/index.php?rid=3266858&cid=t_416849_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2010%2F02%2Fovarian-tumors-primary%2F Pathophysiology 1) neoplastic transformation of the ovaries (can be malignant or benign) 2) classified by cell origin of abnormal growth – epithelial (70%), sex cord stromal (5%-10%), or germ cell (15%-20%) tumors Signs and Symptoms 1) abdominal pain 2) bloating 3) urinary frequency 4) constipation 5) palpable pelvic mass on gynecologic exam 6) granulosa cell tumor (type of sex cord stromal tumor) causes vaginal bleeding and precocious puberty 7) Sertoli/Leydig cell tumors cause virilization and hirsuitism generally do not become symptomatic until late stage Characteristic Test Findings Laboratory – 1) presence of CA-125 tumor marker (occurs in 85% of patients, but very controversial when used as a screening test because other conditions cause increased levels) 2) increased se... Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=3266858 Fri, 12 Feb 2010 03:46:51 +0100 3266858 http://www.medworm.com/index.php?rid=2934818&cid=t_416849_115_f&fid=34670&url=http%3A%2F%2Fsumerdoc.blogspot.com%2F2009%2F10%2Fdermoid-ovary-ct.html Classical CT image of an ovarian dermoid. Reported by Teleradiology ProvidersFrom Sumer's Radiology Site http://www.sumerdoc.blogspot.com -The Top Radiology Magazine. Teleradiology Providers at www.teleradproviders.com Mail us at teleradproviders@gmail.com (Source: Sumer's Radiology Site) Sumer's Radiology Site blogs http://www.medworm.com/rss/comments.php?id=2934818 Tue, 27 Oct 2009 18:06:00 +0100 2934818