MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'glioblastoma multiforme'. Sat, 03 Sep 2011 02:21:47 +0100 http://www.medworm.com/index.php?rid=3529860&cid=t_144868_111_f&fid=39123&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fnursingcomments%2Ftdtc%2F%7E3%2FTefcGgH1jvk%2F           Glioblastoma multiforme (GBM) is by far the most common and most malignant of the glial tumors.  Attention was recently drawn to this form of brain cancer when Senator Ted Kennedy was diagnosed with glioblastoma and ultimately died from it.  It is a deadly brain tumor.  Of the estimated 17,000 primary brain tumors diagnosed in the United States each year, approximately 60% are gliomas.  GBM is an aggressive malignant brain tumor that grows in the glial cells, affecting the nervous system.  According to the National Brain Tumor Society, glioblastoma accounts for approximately 23 percent of all primary brain tumors diagnosed in the U.S.  The prognosis for individuals with glioblastoma depends upon how early the tumor is detected and how quickly treatments begin.  Th... Nursing Comments blogs http://www.medworm.com/rss/comments.php?id=3529860 Mon, 03 May 2010 16:21:23 +0100 3529860 http://www.medworm.com/index.php?rid=3262547&cid=t_144868_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2010%2F02%2Fastrocytoma%2F Pathophysiology 1) primary brain tumor dervied from astrocytes 2) wide variation in differentiation – grade 1 (astrocytoma), grade 2 (anaplastic astrocytoma), grade 3 (glioblastoma multiforme) Signs and Symptoms 1) headaches (especially on waking) 2) vomiting 3) confusion leading to obtundation and coma 4) seizures 5) transtentorial (with fixed and dilated pupils due to CN III damage) or foramen magnum herniation Characteristic Test Findings Radiology – 1) poorly demarcated mass on MRI and CT scan 2) grade 3 – often crosses the midline and assumes “butterfly shpae” 3) grade 3 often with hemorrhage and frequent necrosis Histology/Gross Pathology Grade 1 – 1) well-differentiated astrocytes with a matrix of thin glial processes; but, grossly, tumor is poorl... Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=3262547 Thu, 11 Feb 2010 03:21:34 +0100 3262547 http://www.medworm.com/index.php?rid=2398855&cid=t_144868_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FtSlALmqbICA%2F A cancer medication already available for other cancers, such as breast cancer, has now been given the FDA-go ahead to be used for a type of brain cancer, called glioblastoma multiforme (GBM). Senator Edward Kennedy was diagnosed last year with brain cancer called glioma. GBM is the most advanced of this type of brain cancer. The FDA reported yesterday: The U.S. Food and Drug Administration recently approved Avastin (bevacizumab) to treat patients with glioblastoma multiforme (GBM) when this form of brain cancer continues to progress following standard therapy. GBM is a rapidly progressing cancer that invades brain tissue and can impact physical activities and mental abilities. It affects about 6,700 persons in the United States every year. Following initial treatment with surgery, radiati... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2398855 Sun, 10 May 2009 11:00:41 +0100 2398855 http://www.medworm.com/index.php?rid=2032968&cid=t_144868_115_f&fid=34670&url=http%3A%2F%2Fsumerdoc.blogspot.com%2F2008%2F12%2Fglioblastoma-multiforme-mri.html These are post gd images of a biopsy proven case of GBM showing characteristic non-homogenous enhancement, necrotic areas, spread along white matter tracts and perilesional edema. Teleradiology ProvidersFrom Sumer's Radiology Site http://www.sumerdoc.blogspot.com -The Top Radiology Magazine. Teleradiology Providers at www.teleradproviders.com Mail us at teleradproviders@gmail.com (Source: Sumer's Radiology Site) Sumer's Radiology Site blogs http://www.medworm.com/rss/comments.php?id=2032968 Thu, 11 Dec 2008 09:48:00 +0100 2032968 http://www.medworm.com/index.php?rid=1938846&cid=t_144868_115_f&fid=34670&url=http%3A%2F%2Fsumerdoc.blogspot.com%2F2008%2F11%2Fmulticentric-glioblastoma-multiforme.html We present here a case of multicentric GBM identified with MRI. This is a 73 yr old man, Look at the spread across the corpus callosum and along the white matter tracts in the posterior limb of the internal capsule and into cerebral peduncle.Dr.Sumer K Sethi, MDSr Consultant Radiologist ,VIMHANS and CEO-Teleradiology ProvidersEditor-in-chief, The Internet Journal of Radiology Director, DAMS (Delhi Academy of Medical Sciences) From Sumer's Radiology Site http://www.sumerdoc.blogspot.com -The Top Radiology Magazine. Teleradiology Providers at www.teleradproviders.com Mail us at teleradproviders@gmail.com (Source: Sumer's Radiology Site) Sumer's Radiology Site blogs http://www.medworm.com/rss/comments.php?id=1938846 Thu, 06 Nov 2008 10:09:00 +0100 1938846 http://www.medworm.com/index.php?rid=839150&cid=t_144868_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2F151910480%2F The experimental compound cyclopamine was previously known to shut down a critical cell-signaling pathway (Hedgehog) in the most common and aggressive type of adult brain cancer: glioblastoma multiforme. Now, according to Johns Hopkins scientists, cyclopamine have been able to successfully kill cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy. According to Charles G. Eberhart, M.D., Ph.D., associate professor of pathology, ophthalmology and oncology, who led the work: “Our study lends evidence to the idea that the lack of effective therapies for glioblastoma may be due to the survival of a rare population of cancer stem cells that appear immune to conventional radiation and chemotherapy. Hedgehog inhibition kills these cancer stem cells... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=839150 Tue, 04 Sep 2007 05:46:43 +0100 839150 http://www.medworm.com/index.php?rid=660453&cid=t_144868_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F06%2F06%2Fcancer-by-the-numbers-glioblastoma-multiforme%2F Filed under: Brain Cancer, Cancer by the NumbersGlioblastoma Multiforme (GBM), also known as a grade IV astrocytoma, is the most common and most aggressive type of primary brain tumor. Although GBM can occur at any age, the disease is most commonly diagnosed after the age of 50. I wanted to discuss this type of cancer and add it to the Cancer by the Numbers feature because it has directly affected my family. My 39-year-old uncle died of the disease in 1987. He only survived a year after diagnosis. It is disheartening that this disease has not seen any strides in improved survival rates over all these years. The Numbers GBM accounts for 52 percent of all primary brain tumor cases. Brain tumors account for one in every 100 cancers diagnosed annually in the United States. Most malignant brain... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=660453 Wed, 06 Jun 2007 04:00:00 +0100 660453