MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'gout'. Sat, 03 Sep 2011 02:21:33 +0100 http://www.medworm.com/index.php?rid=5174865&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FSbGm4lXB2Kw%2F Welcome back. This was a long weekend thanks to the hurricane that swept past the Pharmalot corporate campus and inundated the surrounding region. We are slowly returning to our usual form and reviving our spirits with a needed cup of stimulation. We hope those of you who suffered the storm are doing well. As the Morning Mayor used to say: Every brand new day should be unwrapped like a precious gift. Meanwhile, as we get into gear, here are a few items that should be of interest… Roche Sees Government Austerity Bolstering Diagnostics Unit (Bloomberg News) FDA Asks Novartis For More Data On Gout Drug (Reuters) Pfizer Wins FDA Approval For Targeted Lung Cancer Med (Bloomberg News) India’s Piramal Wants To Buy Ailing Biotechs (Financial Times) More Than Half Of CRO Sales Are Made ... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=5174865 Mon, 29 Aug 2011 12:25:42 +0100 5174865 http://www.medworm.com/index.php?rid=4862921&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FbtRrdLyDk40%2F Earlier this year, a scandal erupted after KV Pharmaceuticals won approval for its Makena drug to prevent premature births and charged $1,500 for treatment, an eye-popping increase for a med that was previously available from compounding pharmacies for $10 to $20 for decades. The move was possible because the FDA approval came with marketing exclusivity under the Orphan Drug Act (see here). The episode prompted accusations of price gouging and forced the FDA to decline to pursue compounders (read this and this). Moreover, the red-hot controversy focused renewed attention on older drugs that are repurposed, win FDA approval and gain a lock on the market that allows prices to be increased dramatically. And so Herb Kohl, who chairs the Senate Special Committee on Aging, and three members of t... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4862921 Wed, 25 May 2011 12:03:41 +0100 4862921 http://www.medworm.com/index.php?rid=4862925&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FYGVnVGNyT4k%2F Hello, everyone, and top of the morning to you. A lovely day is emerging here on the Pharmalot corporate campus, although this will be a busy one as we prepare for those meetings and deadlines. We know you relate, so please join us for a cup of stimulation - our flavor today is Rain Forest Nut. Or grab a bottle of water if you prefer. Meanwhile, here are some tidbits from around the world, such as it is. Hope your day is swell and you achieve your goals. See you later… SEC Expected To Act On Whistleblower Program (Washington Post) Deaths In Pfizer Arthritis Drug Trial Are Under A Microscope (Reuters) Vertex And Its Small, But Experienced Sales Force (Dow Jones) Watson Pays $562M For Generic Drug Developer (Reuters) Bayer and J&J’s Xarelto Prevented Repeat Strokes In Analys... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4862925 Wed, 25 May 2011 12:02:24 +0100 4862925 http://www.medworm.com/index.php?rid=4159248&cid=t_137238_88_f&fid=38129&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Flifeinthefastlane%2FWZHV%2F%7E3%2FQ0X83v71m6M%2F Time to challenge that cerebral cortex and put on those 'mental' dancing shoes as we trip the light fantastic of medical trivia, and lift the latch on the cage of the tiger of tease...so watch out for baboons as you embark on the Funtabulously, Frivolous Friday Five...but first some Corrections (Source: Life in the Fast Lane) Life in the Fast Lane blogs http://www.medworm.com/rss/comments.php?id=4159248 Fri, 12 Nov 2010 09:24:48 +0100 4159248 http://www.medworm.com/index.php?rid=4040796&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FSCuTbxtXbQE%2F Rise and shine, another day has arrived. And we are happy to say that so have we. After an unexpected two-day disappearance due to technical problems, we have returned as fresh as ever. So while we brew the mandatory cup of stimulation in the official Pharmalot cafeteria, please join us as we peruse the news of the world. Have a great day, everyone, and stay in touch… Will Bristol-Myers Buy Actelion? (Reuters) Health Care Fraud In Europe Is Rising (PharmaTimes) FDA To Push For More Investment In Science (Reuters) China’s API Suppliers May Have A Bright Future (OutsourcingPharma) Controversy Erupts Over Gout Drug Price Hike (MedPage Today) Vical Signs Deal To Make HIV Vaccine (Associated Press) Novo Nordisk Invests $73M Into US Plant Expansion (InPharma-Technologist) UK’s... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4040796 Thu, 07 Oct 2010 11:51:23 +0100 4040796 http://www.medworm.com/index.php?rid=4023137&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FTeWjAuI5TVk%2F And so another work will soon draw to a close. How will you spend the weekend? Picking apples? Taking a nap? Staring at the leaves gathering in your yard? For our part, we will watch one of the short people on the football field and take another golfing (miniature golfing, that is). Oh yes, the official Pharmalot mascots need a walk. We hope you have swell plans yourself. Meanwhile, here is the news of the world. And whatever you do this weekend, enjoy and be safe… Medicare Donut Hole Will Be A Boon To Pharma (Bloomberg News) Ex-Mylan Managers Enter Plea (Pittsburgh Post-Gazette) FDA Orders Most Colchicine Pills Off The Market (MedPage Today) Court Dismisses Suit Against Savient For Hiding Data (Associated Press) Eli Lilly Chases New Drugs (The New York Times) Meet The Judge Overseei... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4023137 Fri, 01 Oct 2010 11:38:12 +0100 4023137 http://www.medworm.com/index.php?rid=3973117&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2Fb2h0UB6N-As%2F Rise and shine, everyone. Another day is upon us. But this is a good thing. As one of our favorite sages, the Morning Mayor, used to say: Every brand new day should be unwrapped like a precious gift. While you tug on the ribbon, we will brew the mandatory cup of stimulation and poke around for interesting items. Here, in fact, are a few to help you get started. Have a good one and stay in touch… Roche Rules Out Merging R&D With Genentech (Reuters) Abbott To Close Canadian Baby Formula Plant (Brockville Recorder & Times) China’s BGI And Merck Form Alliance (Bio-IT World) Abbott Fights To Keep Meridia Diet Pill On The Market (Reuters) K-V Pharmaceutical Secures A $20M Loan (Fox Business) Genentech CEO Resigns From Dendreon Board (Xconomy) Cell Therapeutics Appeals FDA R... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3973117 Wed, 15 Sep 2010 11:51:18 +0100 3973117 http://www.medworm.com/index.php?rid=3733295&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FtiZRdI29YBA%2F Here’s a lesson in social media. A number of rheumatologists are battling with URL Pharma over its new Colcrys med for treating gout, which is essentially a version of a very old drug called colchicine. Specifically, they complained about pricing on an online message board, and the drugmaker’s general counsel responded by sending letters to some docs about the “potential risks and liabiilty” of using unapproved versions, The Wall Street Journal writes. URL Pharma didn’t threaten to sue, but warned the docs their comments expose them to liability lawsuits from injured patients. “These are shake-down letters to silence” critics, John Goldman, an Atlanta rheumatologist, tells the paper. He criticized URL in his postings for conducting limited research... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3733295 Wed, 07 Jul 2010 21:23:26 +0100 3733295 http://www.medworm.com/index.php?rid=3645056&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FNaS_mp6oKTA%2F Top of the morning to you. Hope you feel refreshed and energetic. And why not? As the Morning Mayor used to say: ‘Every brand new day should be unwrapped like a precious gift.’ Nothing like a gentle reminder to look on the sunny side, yes? Meanwhile, here are a few items to keep you moving in the right direction. Have a great day and do stay in touch… FDA To Review New Morning After Pill (USA Today) Regeneron, New Drugs And Big Partners (Bloomberg News) Glaxo Cancer Drug Bounced Again By UK’s NICE (Reuters) Pfizer Halts Sale Of Vaccine Linked To Bleeding Calve Syndrome (Herald Scotland) Charles River Shareholder Opposes WuXi Deal (Outsourcing Pharma) Merck Insomnia Drug Improves Sleep: Study (Reuters) Bayer To Emphasize Sales Growth Over Margins (Reuters) pic courte... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3645056 Wed, 09 Jun 2010 11:49:24 +0100 3645056 http://www.medworm.com/index.php?rid=3460394&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FYkwzytadgm4%2F Talk about unintended consequences. Nearly four years ago, the FDA moved to tighten regulation on unapproved drugs, which were sold well before the agency was created. There were about 70 drugs that were grandfathered and considered safe to use, although there were never any proven studies. So the FDA began offering exclusive marketing rights in exchange for conducting clinical trials. So what happened? One company called URL Pharma ran studies on colchicine, a centuries-old salve for gout, and received a three-year deal from the FDA. URL then raised the price - what used to cost a few pennies per tablet now fetches about $5. Meanwhile, URL has sued other companies for allegedly marketing their long-standing versions illegally, The Wall Street Journal writes. URL notes there was no standar... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=3460394 Mon, 12 Apr 2010 12:43:25 +0100 3460394 http://www.medworm.com/index.php?rid=3197567&cid=t_137238_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F01%2F22%2Fthe-lancet-2009-volume-375-issue-9711%2F Contents Page Fade Fave: Gout Fade Skinny: Seminar on gout, a common arthritis caused by deposition of monosodium urate crystals within joints after chronic hyperuricaemia. It affects 1—2% of adults in developed countries, where it is the most common inflammatory arthritis in men. Diet and genetic polymorphisms of renal transporters of urate seem to be the main causal factors of primary gout. Gout and hyperuricaemia are associated with hypertension, diabetes mellitus, metabolic syndrome, and renal and cardiovascular diseases. Non-steroidal anti-inflammatory drugs and colchicine remain the most widely recommended drugs for treatment of acute attacks. Oral corticosteroids could be an alternative. Patient education, appropriate lifestyle advice, and treatment of comorbidities are an import... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3197567 Fri, 22 Jan 2010 09:55:49 +0100 3197567 http://www.medworm.com/index.php?rid=2890574&cid=t_137238_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F10%2F14%2Fannals-of-rheumatic-diseases-2009-vol-68-no-11%2F contents page Fade Fave: Seasonality and trends in the incidence and prevalence of gout in England and Wales 1994–2007 Fade Skinny: Identifies that the incidence of gout is seasonal. This has implications for the management of patients who currently have gout, and for those who are at risk of future attacks. The decreasing trend in the incidence of acute attacks suggests that patient management is improving. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Current Awareness, E-Journals, Epidemiology, Gout (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2890574 Wed, 14 Oct 2009 10:17:11 +0100 2890574 http://www.medworm.com/index.php?rid=2610869&cid=t_137238_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F07%2F16%2Fannals-of-rheumatic-diseases-2009-volume-68-no-8%2F Contents Page Title: Opportunities for improving medication use and monitoring in gout Fade Skinny: Finds variations in patterns of medication use and monitoring in patients with gout with suboptimal care. A concerted effort is needed to improve the overall care of gout. (Requires NHS Athens Password for Access) Posted in Access from Home, Access from Work, Access in the Library, Athens Password, Current Awareness, E-Journals, Electronic Resources Tagged: Athens Password, Current Awareness, Drug Therapy, E-Journals, Gout (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2610869 Thu, 16 Jul 2009 13:09:06 +0100 2610869 http://www.medworm.com/index.php?rid=2287314&cid=t_137238_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F1GrlpumS7D4%2F I’ve written about gout a few times over at Help My Hurt (Hope for people who have gout and Your coffee may help prevent gout). It’s a very painful condition of the joints and it most often hits the big toe, although it can affect other joints as well  (ankles, knees, wrists, fingers, and elbows). More men get it than women. Your body produces uric acid, a waste product that’s in your blood and urine. The uric acid can build up and cause stiff, swollen, red joints. If you’ve ever had a gout attack, you’ll likely do just about anything to prevent another. A new study has shown that vitamin C may help reduce the risk of gout in men. The study, which appeared in the latest issue of the Archives of Internal Medicine , involved following almost 47,000 men from 198... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2287314 Mon, 23 Mar 2009 05:00:07 +0100 2287314 http://www.medworm.com/index.php?rid=2188853&cid=t_137238_83_f&fid=38209&url=http%3A%2F%2Forthopodduffy.medbrains.net%2F2009%2F02%2F14%2Fan-orange-a-day%2F The most common form of inflammatory arthritis in men is gout and hyperuricemia is a precursor of gout. For at least 25 years, metabolic studies have shown that serum uric acid levels can be reduced by taking high doses of vitamin C (ascorbic acid). What is still to be determined is the exact mechanism by which the vitamin is successful in lowering the uric acid levels and the optimum amount of ascorbic acid needed to do that on a daily or other basis. X. Gao et al (J Rheumatology. 2008; 35(9):1853-1858) used a population-based study to examine the association between Vitamin C intake and serum uric acid using a group of 1387 men. The participants were a subsample of the Health Professional Follow-up Study, which started in 1986. It has a total population of 51,529 male... Orthopod online and blogging blogs http://www.medworm.com/rss/comments.php?id=2188853 Sun, 15 Feb 2009 20:14:56 +0100 2188853 http://www.medworm.com/index.php?rid=2134822&cid=t_137238_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2Fk5n1HQOj_qg%2F As we get older we are less likely to throw things away. This was a great problem with my mother, if she couldn’t use something well maybe someone else could. I remember going into her medicine chest to get an aspirin and all of these bottles fell out, scary isn’t it? Upon looking at her medications, I found that some were outdated others written by different doctors, they were also purchased at different pharmacies. I had to convince her to let me toss the outdated medications, we also called the doctors and pharmacies to see if she was putting herself in harms way. If you see more then one doctor you should always supply them with a complete list of your medications. The list needs to include vitamins as well as herbs, because they may react to other prescriptions, always use the sa... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2134822 Mon, 26 Jan 2009 15:00:00 +0100 2134822 http://www.medworm.com/index.php?rid=1991567&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F464959599%2F A bit dreary here in the nation’s medicine chest as we awake to gray skies and a slight drizzle. Still, our spirits are high. And despite the looming holiday here in the US, there is much to do. So time to get started. Here are a few items to help you along. Hope your day is meaningful… AstraZeneca, Abraxis To End Cancer Drug Trial (Reuters) Lilly Outsources Clinical-Data Management (PharmaTimes) Roche Agrees To Pay $50M For Memory Pharma (The Star-Ledger) Crestor Scrips Rise After Jupiter Study (Reuters) Schering-Plough Sees 5 NDAs In 2009 (Dow Jones) FDA Panel OKs New Gout Drug (WebMD) Avandia Riskier Than Actos For Older Diabetics (Philly.com) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1991567 Tue, 25 Nov 2008 11:48:34 +0100 1991567 http://www.medworm.com/index.php?rid=1981291&cid=t_137238_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F460701919%2F And so another work week is about to come to a close. Although today is not yet over, is it? Perhaps another meeting or deadline looms. So as you prepare, here are a few items to help ease the way. Meanwhile, we hope you enjoy your weekend, whatever you do. As always, thanks for stopping by… Glaxo Signs China JV Deal For Flu Vaccine (Dow Jones) No Heart Risk With Takeda Gout Drug: FDA (Reuters) Pfizer Still Interested In Obesity Drugs (Reuters) FDA Clears Glaxo Promacta Blood Clot Drug (Yahoo/AP) FDA Panel Backs New Use For J&J Catheter (Yahoo/AP) CombinatoRx Cuts More Jobs (The Boston Globe) (Source: Pharmalot) Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1981291 Fri, 21 Nov 2008 12:20:48 +0100 1981291 http://www.medworm.com/index.php?rid=1926894&cid=t_137238_88_f&fid=38129&url=http%3A%2F%2Fsandnsurf.medbrains.net%2F2008%2F11%2Flessons-from-our-past%2F Thanks to Holly Tucker from Wonders and Marvels for re-stimulating my love of medical history. There is a wealth of information hidden in chronicles from the past - with much of it still pertinent to medicine today. Just wanted to share the concluding statement from an dissertation on gout by William Cadogan (1711 - 1797).  Cadogan had suffered from gout [...] (Source: Life in the Fast Lane) Life in the Fast Lane blogs http://www.medworm.com/rss/comments.php?id=1926894 Sun, 02 Nov 2008 06:32:35 +0100 1926894 http://www.medworm.com/index.php?rid=1657119&cid=t_137238_115_f&fid=34670&url=http%3A%2F%2Fsumerdoc.blogspot.com%2F2008%2F07%2Fcraniovertebral-gout.html This is an old male patient who is a known case of gout with raised uric acid levels and neck pain. MRI cervical spinhe revealed C1-2 erosions and marrow edema, with retro-odontoid soft tissue which is isointense on T1 WI and hypointense on T2 WI. There was no significant post gadolinium enhancement. CT scan revealed erosive disease and retro-odontoid high density soft tissue. There was no evidence of tuberculosis and rheumatoid factor repeatedly was negative. Although rare but still possible gouty cystal deposition was the provisional diagnosis made and patient was followed up after 3 months with no serial change.Dr.Sumer K Sethi, MDConsultant Radiologist ,VIMHANS and CEO-Teleradiology Providers Editor-in-chief, The Internet Journal of Radiology Director, DAMS (Delhi Academy of Medical Sc... Sumer's Radiology Site blogs http://www.medworm.com/rss/comments.php?id=1657119 Sat, 26 Jul 2008 10:17:00 +0100 1657119 http://www.medworm.com/index.php?rid=1097207&cid=t_137238_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F12%2F16%2Ffructose-its-a-big-part-of-the-problem.html By Dov Michaeli MD, Ph.DHave you ever looked at the list of ingredients on the foods you buy? I can guarantee that you’ll be hard put to find even one item that does not contain fructose in one form or another: it could be straight fructose, or masquerading as corn syrup, or sucrose (table sugar) whose content is 50% fructose. I recently checked 10 items in my foray to the local Safeway store; of the packaged foods, all ten contained fructose in one form or another. It's found in ketchup, fruits, jellies, pastries, and many processed foods. Even sugar substitutes can have high fructose corn syrup in them. So what of it? Plenty.Fructose and metabolic syndromeOne of the hallmarks of metabolic syndrome diagnosis is insulin resistance. What it basically means is the following: When gluco... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=1097207 Sun, 16 Dec 2007 00:45:48 +0100 1097207 http://www.medworm.com/index.php?rid=891464&cid=t_137238_117_f&fid=34612&url=http%3A%2F%2Fwww.thedoctorweighsin.com%2Fjournal%2F2007%2F9%2F21%2Fwhats-all-the-fuss-about-lead.html Poor Mattel; three huge recalls of lead-tainted toys, despite conscientious testing efforts. Those babe-in-the-woods quality control experts were no match to the wily new capitalists from China, determined to maximize profit. Isn’t that the name of the game?What’s next? A toxic Barbie? That may actually be a blessing in disguise.But, it’s not only toys. Here is an item from today’s San Jose Mercury:Lunchbox warning: Health officials say toss themUNSAFE LEVEL OF LEAD FOUND IN GIVEAWAYSBy Steven HarmonMediaNews Sacramento BureauArticle Launched: 09/21/2007 01:33:38 AM PDTSACRAMENTO - "The state's public health department asked parents Thursday to toss certain Chinese-made lunchboxes potentially containing dangerous levels of lead - the same ones it distribut... The Doctor Weighs In blogs http://www.medworm.com/rss/comments.php?id=891464 Fri, 21 Sep 2007 23:33:33 +0100 891464