MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'growth factor'. Sat, 03 Sep 2011 02:37:47 +0100 http://www.medworm.com/index.php?rid=4664103&cid=t_396138_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2011%2F04%2Fsquamous-cell-carcinoma-skin%2F Pathophysiology neoplasm of keratinizing epidermal cells Signs and Symptoms 1) presents in variable forms – ulcerated nodule, superficial erosion, or verrucous papule or plaque 2) ill-defined margins 3) can be fixed to underlying structures 4) has metastatic potential (1%-3%) Histology/Gross Pathology premalignant forms – 1) actinic keratoses 2) actinic cheilitis 3) Bowen’s disease Associated Conditions 1) cumulative exposure to sunlight (especially UV-B) 2) arsenic 3) cyclic aromatic hydrocarbons in tar and soot 4) cigarette smoking and oral tobacco 5) chronic immunosuppression 6) HIV 7) burns 8) chronic ulceration/wounds 9) xeroderma pigmentosa 10) some forms of albinism Biochemistry 1) considered an angiogenic tumor 2) inactivation of p53 tumor-suppressor gene 3) downr... Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=4664103 Fri, 01 Apr 2011 05:59:54 +0100 4664103 http://www.medworm.com/index.php?rid=4168208&cid=t_396138_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2FWoFKcVzc854%2F Mention the phrase ‘white paper’ and an authoritative guide to a particular policy issue may spring to mind. Of course, white papers may also be nothing more than promotional thoughts dressed up as think pieces. And that’s what the FDA has decided the Ipsen Group did in creating and distributing a paper about Insulin-like Growth Factor Deficiency, an affliction in which growth is inhibited. In a recently disclosed warning letter, the agency took Ipsen to task for omitting important risk info and broadenening the indication for its Increlex treatment. But the underlying issue was that the white paper wasn’t really a white paper and there were several tell-tale signs that offer some interesting insight into agency thinking on such situations. To wit, the FDA noted the... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=4168208 Mon, 15 Nov 2010 17:13:53 +0100 4168208 http://www.medworm.com/index.php?rid=3460419&cid=t_396138_167_f&fid=38576&url=http%3A%2F%2Fwww.drbriffa.com%2Fblog%2F2010%2F04%2F12%2Fcan-milk-cause-acne%2F My post last Friday concerned my ‘love-hate’ relationship with dairy products – I generally like the way they taste, but am also acutely aware that they can quite-often trigger health issues in myself and others. I first leaned this when the elimination of cow’s milk products 20-odd years ago eliminated my eczema too. Other symptoms [...] (Source: Dr John Biffa's Blog) Dr John Biffa's Blog blogs http://www.medworm.com/rss/comments.php?id=3460419 Mon, 12 Apr 2010 11:52:10 +0100 3460419 http://www.medworm.com/index.php?rid=2614008&cid=t_396138_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2F26P7O1fRDg0%2F I know this sounds off-topic for a human-health blog, but bear with me in this: Dog researchers have discovered a gene event that may have implications for understanding human dwarfism. Published early in Science, scientists found that those cute-looking short-legged dog pedigrees that include Bassett Hounds and Dachshunds are products of a single mutational event in the dog evolution. Somewhere in evolution when dogs separated from the wolves, a mutation caused certain dogs to have short legs, and that mutation was preserved through time to create the modern-day short-leg breeds like the dachshund, corgi, Pekingese and basset hound. In these dogs, scientists found an extra copy of a gene that codes for a growth-promoting protein called fibroblast growth factor 4 (FGF4). The extra gene ... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2614008 Fri, 17 Jul 2009 19:28:50 +0100 2614008 http://www.medworm.com/index.php?rid=1918042&cid=t_396138_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2Fjvux56F3-bg%2F Malnourishment in a pregnant woman has a lasting effect on her child’s DNA. This was the implications of a new study on children born during the famine of World War II. Scientists studied the DNA of children who were born to women starved during the 1944 Hunger Winter in the Netherlands. They analyzed a gene called insulin-like growth factor 2 or IGF2, an important growth hormone. Methyl groups that attach to IGF2 very early in fetal development determine how much of the growth hormone is made later, and protect the DNA from damage. The scientists found that those children (now in their 60s)  who were exposed to famine in the first trimester of pregnancy had lesser methyl groups in the IGF2 gene than their siblings of the same sex. Loss of methylation in IGF2 has previously b... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=1918042 Thu, 30 Oct 2008 11:00:46 +0100 1918042 http://www.medworm.com/index.php?rid=1727802&cid=t_396138_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2008%2F08%2F03%2Fcombination-targeted-therapy-with-sorafenib-bevacizumab-shows-antitumor-activity%2F The results from a recent Phase I solid tumor clinical trial indicate that combination targeted therapy with sorafenib and bevacizumab produces anti-tumor activity (and enhanced toxicity) with respect to 43% of the ovarian cancer patients enrolled in that trial. Sorafenib (Nexavar®) inhibits the Raf kinase and vascular endothelial growth factor (VEGF) receptor. Bevacizumab (Avastin®) is [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=1727802 Mon, 04 Aug 2008 02:36:13 +0100 1727802