MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'hodgkin'. Sat, 03 Sep 2011 03:02:20 +0100 http://www.medworm.com/index.php?rid=4118944&cid=t_285970_88_f&fid=38129&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Flifeinthefastlane%2FWZHV%2F%7E3%2FWAKfyhUbUq0%2F Time to challenge that cerebral cortex and put on those 'mental' dancing shoes as we trip the light fantastic of medical trivia, and lift the latch on the cage of the tiger of tease...so watch out for baboons as you embark on the Funtabulously, Frivolous Friday Five... (Source: Life in the Fast Lane) Life in the Fast Lane blogs http://www.medworm.com/rss/comments.php?id=4118944 Fri, 29 Oct 2010 00:05:31 +0100 4118944 http://www.medworm.com/index.php?rid=3666242&cid=t_285970_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F06%2Fsystems-biology-approach-shows-myb-and-foxm1-as-master-regulators-of-germinal-center-proliferation.html Back from a relaxing stay-cation as well as ASCO meeting--The June 2010 issue of Molecular Systems Biology has a fascinating study identifying MYB and FOXM1 as "master regulators" of germinal center proliferation in lymph nodes.  Why should we as pathologists care about this?What piqued my curiosity here was a connection with my previous post summarizing what I learned at USCAP on the molecular pathology of diffuse large B-cell lymphoma (DLBCL) regarding dysregulated genes in DLBCL (including MYC) and identification of three gene expression subgroups, including the "germinal center B-cell-like" group.The authors use some fascinating and powerful techniques around a systems biology approach to find master regulator genes controlling specific cellular processes (in ... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=3666242 Wed, 16 Jun 2010 02:24:22 +0100 3666242 http://www.medworm.com/index.php?rid=3505152&cid=t_285970_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F04%2Fpart-3-molecular-testing-in-lymphoma-uscap-2010.html Final recap from Dr. Adam Bagg's lecture at USCAP 2010 on molecular testing in lymphoma.  The highpoint of the lecture for me was his comments on diffuse large B-cell lymphoma (DLBCL) since this is the most common lymphoma type we see in our practice.  It so happens that there have been some recent papers that I've read that complement Dr. Bagg's lecture notes and I cite those below.  I think if you consider his comments and have a look at these papers, you should be well-prepared for the next DLBCL you see.DLCBL is the most common lymphoma in adults but it is a heterogeneous clinical, morphological, immunophenotypic, molecular, and genetic "category."  Some differences in clinical behavior can be predicted by the recognition of certain between... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=3505152 Mon, 26 Apr 2010 15:00:00 +0100 3505152 http://www.medworm.com/index.php?rid=3501724&cid=t_285970_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F04%2Fpart-2-molecular-testing-in-lymphoma-uscap-2010.html This is continuation from my previous "recap of USCAP" post on Dr. Adam Bagg's presentation on molecular testing in lymphoma from the Special Course on basic molecular biology at the 2010 USCAP meeting. This post deals with his comments on follicular lymphoma.The cytogenetic hallmark of follicular lymphoma (FL) is t(14;18)(q32,;q21) involving the IgH chain gene on chromosome 14 and BCL2 on chromosome 18 and this translocation is identified in about 90% of cases of FL. This translocation results in overexpression of bcl-2 protein which protects the cell from apoptosis.  Most of the remaining 10% of cases that do not show the translocation show bcl-2 protein overexpression by other mechanisms.This translocation is not specific for FL and can be seen in up to 2... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=3501724 Sat, 24 Apr 2010 15:33:24 +0100 3501724 http://www.medworm.com/index.php?rid=3429468&cid=t_285970_155_f&fid=38412&url=http%3A%2F%2Fpathlabmed.typepad.com%2Fsurgical_pathology_and_la%2F2010%2F03%2Fmolecular-testing-in-lymphoma-uscap-2010.html More from the Special Course, "Basic Principles and Practice of Molecular Pathology in Cancer," that I attended at the USCAP 2010 meeting.Dr. Adam Bagg delivered a lively presentation on molecular testing in lymphoma as part of the Special Course, "Basic Principles and Practice of Molecular Pathology in Cancer" at USCAP 2010.  This is part 1 of my take-home points: Rearrangements are the most clinically relevant genetic changes in hematolymphoid malignancies and can be generally divided into two broad categories-- Quantitative (that is, physiologic/antigen receptor gene rearrangements): detecting homogeneity (monoclonal) versus heterogeneity (polyclonal).  This is more characteristic of lymphoid malignancies.  The prototype is where a contextual... The Daily Sign-Out blogs http://www.medworm.com/rss/comments.php?id=3429468 Thu, 01 Apr 2010 04:21:45 +0100 3429468 http://www.medworm.com/index.php?rid=4245503&cid=t_285970_136_f&fid=35285&url=http%3A%2F%2Fwww.glamour.com%2Fhealth-fitness%2Fblogs%2Flife-with-cancer%2F2009%2F05%2Frefusing-treatment-you-wont-be.html Have you guys seen this crazy story? About a mom who is refusing to have her child go through chemotherapy for one of the most beatable cancers out there...hodgkins lymphoma. It's a religious thing—the family believes in natural healing methods. They are actually attempting to treat a completely curable disease with "herbal supplements, vitamins, ionized water and other natural alternatives." You may disagree with me but I have to say... (Source: Life with Cancer) Life with Cancer blogs http://www.medworm.com/rss/comments.php?id=4245503 Wed, 20 May 2009 14:00:30 +0100 4245503