MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'increased risk'. Sat, 03 Sep 2011 02:58:27 +0100 http://www.medworm.com/index.php?rid=3448809&cid=t_102786_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2010%2F04%2F08%2Fbabys-size-related-to-diabetes-study-says%2F Filed under: Daily NewsSmaller-than-normal babies have higher rates of type 2 diabetes when they grow up, but doctors have never understood why, until now. According to scientists, who published their findings in Nature Genetics, there are two genetic regions that affect a baby's size at birth. One of them is also linked with developing diabetes later in life. The research, which involved analyzing the results of more than 38,000 Europeans from 19 different studies, confirms that people who inherit two copies of a variant gene have a 25 percent higher risk of diabetes in adulthood than those who do not. "Our study shows that genes are part of the reason why babies born with a lower birth weight are more at risk of type 2 diabetes 50 or 60 years later," Rachel Freathy, Ph.D., a Sir Henr... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=3448809 Wed, 07 Apr 2010 23:00:00 +0100 3448809 http://www.medworm.com/index.php?rid=3251154&cid=t_102786_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2010%2F02%2Fdowns-syndrome-trisomy-21%2F Pathophysiology congenital mental retardation caused by trisomy 21 (an extra chromosome 21) Signs and Symptoms 1) moderate mental retardation progressing to severe mental retardation (IQ of 30 in adulthood) 2) characteristic mongoloid facies – flat nasal bridge, epicanthic folds, oblique palpebral fissures 3) short stature and obesity 4) spade-like hands with simian creases 5) speckled irises (Brushfield’s spots) 6) hypotonia 7) congenital heart defects – VSD, ASD, tetralogy of Fallot, and patent ductus arteriosus Associated Conditions 1) increased incidence with advanced maternal age (1/30 live births at age 45 years) and previous child with Down syndrome 2) increased incidence of leukemia (especiallly ALL), Alzheimer’s disease (25-50%) by age 35 years), Hirschspru... Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=3251154 Sun, 07 Feb 2010 23:10:19 +0100 3251154 http://www.medworm.com/index.php?rid=863732&cid=t_102786_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F09%2F11%2Fprevention-zeroes-in-on-families-of-heart-disease-sufferers%2F Filed under: Family history, PreventionEarlier this year, my great-aunt passed away suddenly from an unknown heart condition. Her doctor recommended that all of her siblings, children, and nieces and nephews be screened for heart problems as well, flagging them at a higher risk for developing cardiovascular disease. Thankfully, no problems were uncovered, but they are now aware of the higher risk associated with having heart disease in our family.Scottish researchers believe that if family members of those with known heart disease were singled out as high-risk and their risk factors gotten under control, up to 40% of early deaths from cardiac events could be prevented. Even so, this type of flagging system is rarely used, even though it is common procedure among families with genetic cance... The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=863732 Tue, 11 Sep 2007 04:00:00 +0100 863732 http://www.medworm.com/index.php?rid=658843&cid=t_102786_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F06%2F05%2Fdiabetics-taking-avandia-caught-in-volley-of-debate%2F Filed under: Type 2, Adult Onset, DrugsFor those of you following the Avandia story in the news, you're probably wondering how the patients currently taking Avandia are feeling. Are they flushing the pills down the toilet? What about the patients enrolled in GlaxoSmithKline's current Avandia clinical trial -- are they dropping out like flies? If you are unfamiliar with the Avandia debate, news broke last week that Avandia, a popular diabetes drug, may increase the risk of heart attack. A 43% higher risk. It may depend on the specialty of your doctor. BusinessWeek has reported endocrinologists tend to be more skeptical of the study, noting its weaknesses compared to original, more rigorous clinical trials. Many cardiologists and drug safety experts give the study more weight, and remain wo... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=658843 Tue, 05 Jun 2007 04:00:00 +0100 658843 http://www.medworm.com/index.php?rid=650906&cid=t_102786_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F06%2F01%2Favandia-controversy-stirs-congress-to-investigate-fda%2F Filed under: Type 2, Adult Onset, Drugs, Research, Daily News Remember learning about "checks and balances" in U.S. History class? When state leaders gathered in 1787 to draft the Constitution, they established three branches of government (legislative/executive/judicial) to protect individual freedom and prevent government from abusing its own power. Now, Congress is questioning the balance of powers over at the Food and Drug Administration (FDA). Republicans and Democrats in the House and Senate have called for an investigation into the FDA in the wake of the New England Journal of Medicine study which suggests the popular diabetes medication, Avandia, significantly increases the risk of heart attacks. A House hearing is set for June 6. Original trials by the drug's maker, GlaxoSmithKlin... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=650906 Fri, 01 Jun 2007 04:00:00 +0100 650906 http://www.medworm.com/index.php?rid=644950&cid=t_102786_87_f&fid=34867&url=http%3A%2F%2Fwww.thediabetesblog.com%2F2007%2F05%2F30%2Fpopular-diabetes-drug-avandia-poses-heart-attack-risk-for-type-2%2F Filed under: Type 2, Adult Onset, DrugsWhen my mom was first diagnosed with diabetes in the late 1990s, her internist prescribed Rezulin, a popular diabetes drug approved in 1997. Then one day the phone rang. Her internist called to alert her Rezulin was causing fatal liver failure and he wanted her off the drug immediately. Now Avandia, a popular diabetes drug which helps sensitize the body to insulin, is on the hotseat. A recent study published in the New England Journal of Medicine by Dr. Steven Nissen and statistician Kathy Wolski at the Cleveland Clinic suggests Avandia significantly raises the risk of heart attack for type 2 diabetics. Nissen pooled results of nearly 28,000 people across dozens of studies, revealing a 43 percent higher risk of heart attack for Avandia users compared ... The Diabetes Blog blogs http://www.medworm.com/rss/comments.php?id=644950 Wed, 30 May 2007 04:00:00 +0100 644950