MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'infarction'. Sat, 03 Sep 2011 02:04:36 +0100 http://www.medworm.com/index.php?rid=5029211&cid=t_161714_150_f&fid=35777&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FPharmalot%2F%7E3%2F2TajULYXlqU%2F Last month, a widely publicized study raised concerns about the safety of the blockbuster Spiriva inhaler that is used to treat chronic obstructive pulmonary disease. The meta-analysis published in the British Medical Journal found that, when administered in the mist form known as Respimat, there was a 52 percent increase in mortality risk compared with a placebo (see here). Not surprisingly, Boehringer Ingelheim, which makes the inhaler, disagreed. And in disputing the findings, the drugmaker made a point of saying the results were not based on new clinical evidence and that the meta-analysis relied on already publicly available data. BI also maintained that “robust evidence” has also been published about the safety of the older, powder version known as HandiHaler (read the statement)... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=5029211 Thu, 14 Jul 2011 16:25:23 +0100 5029211 http://www.medworm.com/index.php?rid=4828881&cid=t_161714_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fheart-attack-survivors-should-avoid-certain-pain-medicines-nsaids%2F2011.05.17 This study looked at patients who had already had an MI.  But for those patients, the over-the-counter pain relievers should be avoided.  Many patients with heart disease also have arthritis or other pain syndromes.  We need to come up with safe treatments for pain or use “safer” NSAIDs like low dose Naprosyn or Ibuprofen only when the benefit is weighed with the risk. Just because something is sold without a prescription does not mean it is without risk.  Tell your doctor every medication you take. *This blog post was originally published at EverythingHealth* (Source: Better Health) Better Health blogs http://www.medworm.com/rss/comments.php?id=4828881 Tue, 17 May 2011 12:00:00 +0100 4828881 http://www.medworm.com/index.php?rid=4803135&cid=t_161714_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fcalcium-supplements-good-for-your-bones-but-bad-for-your-heart%2F2011.05.10 Calcium is good for us, right? Milk products are great sources of calcium, and we’re told to emphasize milk products in our diets. Don’t (or can’t) eat enough dairy? Calcium supplements are very popular, especially among women seeking to minimize their risk of osteoporosis. Osteoporosis prevention and treatment guidelines recommend calcium and vitamin D as an important measure in preserving bone density and reducing the risk of fractures. For those who don’t like dairy products, even products like orange juice and Vitamin Water are fortified with calcium. The general perception seemed to be that calcium consumption was a good thing – the more, the better. Until recently. In a pattern similar to that I described with folic acid, there’s new safety signals from trials with calciu... Better Health blogs http://www.medworm.com/rss/comments.php?id=4803135 Tue, 10 May 2011 13:00:59 +0100 4803135 http://www.medworm.com/index.php?rid=4615110&cid=t_161714_88_f&fid=38129&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Flifeinthefastlane%2FWZHV%2F%7E3%2FgbEuKJm-LT8%2F Brilliant images illustrating the art of myocardial infarct localisation by ECG interpretation. (Source: Life in the Fast Lane) Life in the Fast Lane blogs http://www.medworm.com/rss/comments.php?id=4615110 Mon, 21 Mar 2011 11:52:44 +0100 4615110 http://www.medworm.com/index.php?rid=4045095&cid=t_161714_87_f&fid=39187&url=http%3A%2F%2Fgetbetterhealth.com%2Fsex-and-your-defibrillator%2F2010.10.08 Have a defibrillator and feel like getting frisky? For the first time that I can recall, there’s a very helpful article published in Circulation addresses the concerns of implantable cardiac defibrillator (ICD) patients and sexual activity. There’s all kinds of helpful tidbits, like this one: A study of 1,774 patients who had experienced an acute myocardial infarction showed that sexual activity was a likely contributor in fewer than 1 percent of cases. In fact, regular physical exertion, such as that associated with sexual activity, was associated with a decreased risk of cardiac events in patients. Now that’s helpful! Recall that defibrillators are designed to detect rapid, potentially life-threatening arrhythmias. Most of the time, sexual activity does not lead to hea... Better Health blogs http://www.medworm.com/rss/comments.php?id=4045095 Fri, 08 Oct 2010 14:00:00 +0100 4045095 http://www.medworm.com/index.php?rid=4040502&cid=t_161714_83_f&fid=34856&url=http%3A%2F%2Finsidesurgery.com%2F2010%2F10%2Fmyocardial-infarction-signs-symptoms%2F Dressler’s syndrome, “crushing” chest pain (Source: Inside Surgery) Inside Surgery blogs http://www.medworm.com/rss/comments.php?id=4040502 Thu, 07 Oct 2010 06:19:27 +0100 4040502 http://www.medworm.com/index.php?rid=3802423&cid=t_161714_105_f&fid=35048&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FMedicineAndMan%2F%7E3%2FkTgtjIRu6nA%2F Interstroke Study published in the Lancet identified that 10 risk factors caused 88-90% of all strokes (both hemorrhagic and ischemic). 1. Hypertension 2. Current smoking 3. Low waist to hip ratio 4. Unhealthy diet 5. Lack of regular exercise 6. Moderate or high alcohol intake 7. Psychosocial stress 8. Depression 9. High ratio of apoB to apoA1 lipoprotein (i.e. high cholesterol) 10. Diabetes Reference: Interstroke Study, Lancet addthis_url = 'http%3A%2F%2Fmedicineandman.com%2Fblog%2F2010%2F07%2F29%2F10-risk-factors-cause-90-of-stroke%2F'; addthis_title = '10+Risk+Factors+cause+90%25+of+Strokes'; addthis_pub = ''; (Source: Medicine and Man) Medicine and Man blogs http://www.medworm.com/rss/comments.php?id=3802423 Thu, 29 Jul 2010 23:09:47 +0100 3802423 http://www.medworm.com/index.php?rid=3721720&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F07%2F02%2Foxygen-therapy-for-acute-myocardial-infarction%2F Cochrane Review: Oxygen therapy for acute myocardial infarction The Skinny: Finds no conclusive evidence from randomised controlled trials to support the routine use of inhaled oxygen in patients with acute Acute Myocardial Infarction. A definitive randomised controlled trial is urgently required given the mismatch between trial evidence suggestive of possible harm from routine oxygen use and recommendations for its use in clinical practice guidelines. Filed under: Cardiovascular Diseases, Clinical Governance, Current Awareness, Evidence Based Practice, Heart Diseases Tagged: Current Awareness, Evidence Based Practice, Myocardial Infarction, Oxygen Therapy, Systematic Reviews (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3721720 Fri, 02 Jul 2010 10:06:07 +0100 3721720 http://www.medworm.com/index.php?rid=3635699&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2010%2F06%2F07%2Fheart-2010-vol-96-no-8%2F Heart 2010 (Vol. 96 No. 8) Contents page Fade Fave: The effect of optimal medical therapy on 1-year mortality after acute myocardial infarction Fade Skinny: Assesses whether the benefits of combining spirin, β-blockers, statins, renin angiotensin system (RAS) blockers and thienopyridines (termed optimal medical therapy, OMT), will result in a reduction of mortality in clinical practice. Finds that OMT over 1 year was associated with a significantly lower mortality of patients with acute myocardial infarction in clinical practice. However OMT is provided to less than half of eligible patients leaving room for substantial improvement. (NHS Athens is required to access this article online) Filed under: Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Current Awarene... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3635699 Mon, 07 Jun 2010 09:27:28 +0100 3635699 http://www.medworm.com/index.php?rid=3595548&cid=t_161714_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D8564 There’s an old joke which goes something like this: Patient: Doctor, is it OK to have sex after my heart attack? Doctor: It’s OK but no undue excitement, so only with the wife. On a serious note, it is something which is probably under-discussed particularly in the Asian context where open talk about sex are relatively “taboo” and where both doctors and patients are rather reticent about discussing this issue. Nevertheless, it is an important topic, particular for patients recovering from a heart attack, and it is timely that our cardiologist blogger has posted about Sex after a heart attack. HOTM’s wise words: The lesson I learn is that sex is part of normal life and age is no barrier. Even following a heart attack, many still wish to have sex. However, becau... Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=3595548 Mon, 24 May 2010 23:00:00 +0100 3595548 http://www.medworm.com/index.php?rid=3501541&cid=t_161714_105_f&fid=38964&url=http%3A%2F%2Fdrwes.blogspot.com%2F2010%2F04%2Fcosts-of-heart-attack.html Quite a bit, according to some:According to an article from the National Business Group on Health, the average total (editor's note: lifetime) cost of a severe heart attack–including direct and indirect costs–is about $1 million. Direct (lifetime) costs include charges for hospitals, doctors and prescription drugs, while the indirect costs include lost productivity and time away from work. The average (lifetime) cost of a less severe heart attack is about $760,000. Amortized over 20 years, that’s $50,000 per year for a severe heart attack and $38,000 per year for a less severe heart attack.I'm all for maintaining a healthy lifestyle, but before we get all hot and bothered about performing more testing to "prevent" a heart attack as a means to save health care costs going forward, rem... Dr. Wes blogs http://www.medworm.com/rss/comments.php?id=3501541 Sat, 24 Apr 2010 14:59:00 +0100 3501541 http://www.medworm.com/index.php?rid=3501542&cid=t_161714_105_f&fid=38964&url=http%3A%2F%2Fdrwes.blogspot.com%2F2010%2F04%2Fcould-heart-attack-during-trial-help.html Perhaps:Assistant U.S. Attorney Christopher Graveline wrote in a motion that after the judge told the jury about the heart attack “many jurors in their body language and facial expressions, rightly expressed concern for Mr. Cicchetti.” The prosecutor said the government did not object to the judge telling the jury about the heart attack because it assumed that Cicchetti would be prosecuted later before a different jury.“It is only natural for the jury to feel sympathy for Mr. Cicchetti’s condition and this sympathy may well play into its consideration of the evidence against Mr. Cicchetti especially in light of his defense that he is a sick harmless older man who is only guilty of loving motorcycles and cocaine.”“The government believes that allowing Mr. Cicchetti to continue i... Dr. Wes blogs http://www.medworm.com/rss/comments.php?id=3501542 Sat, 24 Apr 2010 14:39:00 +0100 3501542 http://www.medworm.com/index.php?rid=3314640&cid=t_161714_105_f&fid=38964&url=http%3A%2F%2Fdrwes.blogspot.com%2F2010%2F02%2Fdont-abandon-manual-blood-pressure.html ... they might help preserve myocardium:333 consecutive adult patients with a suspected first acute myocardial infarction were randomly assigned in a 1:1 ratio by computerised block randomisation to receive primary percutaneous coronary intervention with (n=166 patients) versus without (n=167) remote conditioning (intermittent arm ischaemia through four cycles of 5-min inflation and 5-min deflation of a blood-pressure cuff). Allocation was concealed with opaque sealed envelopes. Patients received remote conditioning during transport to hospital, and primary percutaneous coronary intervention in hospital. The primary endpoint was myocardial salvage index at 30 days after primary percutaneous coronary intervention, measured by myocardial perfusion imaging as the proportion of the area at ris... Dr. Wes blogs http://www.medworm.com/rss/comments.php?id=3314640 Fri, 26 Feb 2010 21:55:00 +0100 3314640 http://www.medworm.com/index.php?rid=3104974&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F19%2Fheart-2010-vol-96-no-1%2F Contents page Fade Fave: Epidemiology: Out-of-hospital cardiac arrest in South Asian and white populations in London: database evaluation of characteristics and outcome Fade Skinny: Compares out-of-hospital cardiac arrest (OOHCA) characteristics in white and South Asian populations within Greater London. Supports the emerging view that South Asians’ high mortality from coronary heart disease reflects higher incidence rather than higher case fatality. South Asians had an OOHCA at a significantly younger age. The study demonstrates the importance of ethnic coding within the emergency services. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Current Awareness, E-Journals, Epidemiology, Ethnic Groups, H... Fade Library blogs http://www.medworm.com/rss/comments.php?id=3104974 Sat, 19 Dec 2009 05:56:53 +0100 3104974 http://www.medworm.com/index.php?rid=3084732&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F14%2Foccupational-and-environmental-medicine-2009-volume-66-number-12%2F Fade Fave: Traffic particles and occurrence of acute myocardial infarction: a case–control analysis Fade Skinny: Models exposure to traffic particles using a latent variable approach and investigated whether long-term exposure to traffic particles is associated with an increase in the occurrence of acute myocardial infarction (AMI) using data from a population-based coronary disease registry. Provides some support for an association between long-term exposure to traffic particles and risk of AMI. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Air Pollution, Athens Password, Current Awareness, E-Journals, Heart Diseases, Myocardial Infarction, Pollution (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3084732 Mon, 14 Dec 2009 09:00:07 +0100 3084732 http://www.medworm.com/index.php?rid=3084734&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F12%2F14%2Fheart-2009-vol-95-no-22%2F Contents page Fade Fave: Potential survival gains in the treatment of myocardial infarction Fade Skinny: Evaluates the potential impact of complete implementation of guideline recommendations in myocardial infarction (MI) care, and contrast this with new innovations. Finds that potential gains from improved clinical effectiveness in MI care are likely to compare favourably with benefits achieved though innovations, and should inform priorities in research and implementation strategies for improving MI outcomes. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Athens Password, Clinical Effectiveness, Current Awareness, E-Journals, Guidelines, Myocardial Infarction (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=3084734 Mon, 14 Dec 2009 08:30:17 +0100 3084734 http://www.medworm.com/index.php?rid=2924774&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2009%2F10%2F25%2Fheart-2009-vol-95-no-21%2F Contents page Fade Fave: Effects of air pollution on the incidence of myocardial infarction Fade Skinny: Systematic review finding some evidence that short-term fluctuations in air pollution affect the risk of Myocardial Infarction. However, further studies are needed to clarify the nature of these effects and identify vulnerable populations and individuals. (NHS Athens is required to access this article online) Posted in Athens Password, Current Awareness, E-Journals Tagged: Air Pollution, Athens Password, Current Awareness, E-Journals, Heart Diseases, Myocardial Infarction (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=2924774 Sun, 25 Oct 2009 09:04:55 +0100 2924774 http://www.medworm.com/index.php?rid=2785998&cid=t_161714_109_f&fid=38950&url=http%3A%2F%2Fwww.shockmd.com%2F2009%2F09%2F04%2Fchocolate-lowers-cardiac-mortality-after-first-acute-myocardial-infarction%2F Chocolate consumption was associated with lower cardiac mortality in a dose dependent manner in patients free of diabetes surviving their first Acute Myocardial Infarction. In contrast, intake of other sweets was not associated with cardiac or total mortality. Now be aware that Dr Shock is extremely biased when it comes to chocolate but this conclusion is based on a study done in Sweden and recently published in the Journal of Internal Medicine. This was an observational study, in need of confirmation by more scientifically superior designs such as a study with a large scale, long-term, controlled randomized trials. Having said all this what they did was following 1169 patients without diabetes who were hospitalized for a confirmed nonfatal first acute myocardial infarction (”heart ... Dr Shock MD PhD blogs http://www.medworm.com/rss/comments.php?id=2785998 Fri, 04 Sep 2009 07:09:41 +0100 2785998 http://www.medworm.com/index.php?rid=2576524&cid=t_161714_87_f&fid=38368&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FDisruptiveWomenInHealthCare%2F%7E3%2FCUMEh6hQNJg%2F Should managed care sue patients? We arrive at the dawn of yet-another health reform effort with laws and regulations already in place to protect patients. These arose in past decades when the healer-patient relationship was eroding, presumably at the hands of uncaring clinicians and for-profit medical enterprises.    The list of those rights was extensive and today’s debates are adding to the mix – guaranteed coverage despite pre-existing conditions comes to mind. The discussion of patient rights has always been politically attractive and I won’t denigrate any one of them. I’m not just writing from a policy perspective, but a personal one as well. I’m a patient, too. The discussions of patients’ rights, however, has neglected the flip side of rights—responsibilities on the... Disruptive Women in Health Care blogs http://www.medworm.com/rss/comments.php?id=2576524 Mon, 06 Jul 2009 19:43:58 +0100 2576524 http://www.medworm.com/index.php?rid=2458187&cid=t_161714_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2FDedSv3aWBdc%2F If you have had a heart attack (a myocardial infarction ), chances are you’ve been living with exhaustion and fatiuge - sometimes extreme exhaustion - since your heart attack. If it helps, you’re not the only one. It seems that exhaustion is common after having a heart attack and it often makes people think that their whole situation is chronic. Researchers say that around half of the patients in their study of 200 patients said that they felt quite fatigued still 4 months after their heart attack. Interestingly, what the patients reported was that the fatigue was new and different, not like what they had experienced before. The exhaustion wasn’t connected to anything particular, such as increased activity or staying up late, but that it could strike at any time at all. Y... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=2458187 Sat, 06 Jun 2009 11:00:11 +0100 2458187 http://www.medworm.com/index.php?rid=2311095&cid=t_161714_105_f&fid=35048&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FMedicineAndMan%2F%7E3%2FmKkkYfx8ets%2F We report that cardiomyocytes renew, with a gradual decrease from 1% turning over annually at the age of 25 to 0.45% at the age of 75. Fewer than 50% of cardiomyocytes are exchanged during a normal life span.” This finding opens up possibilities of targeting medications to regenerating the heart muscle that is destroyed in a heart attack, thereby preventing a host of complications including heart failure (post myocardial infarction congestive heart failure is the number one cause of heart failure in the United States and is the major contributer of morbidity & mortality after heart attack). Reference: Science, US News addthis_url = 'http%3A%2F%2Fmedicineandman.com%2Fblog%2F2009%2F04%2F04%2Fregenerating-heart-muscles-to-treat-heart-failure%2F'; addthis_title = 'Regenerating+h... Medicine and Man blogs http://www.medworm.com/rss/comments.php?id=2311095 Sat, 04 Apr 2009 19:58:54 +0100 2311095 http://www.medworm.com/index.php?rid=1960815&cid=t_161714_105_f&fid=35048&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FMedicineAndMan%2F%7E3%2F452379995%2F Animated video explaining how coronary angioplasty with stent insertion is performed. Also called percutaneous coronary intervention (PCI), it is the procedure of choice for most cases of heart attack. Coronary artery bypass grafting is performed for severe disease as in involvement of all 3 coronary vessels or left main coronary artery.   addthis_url = 'http%3A%2F%2Fmedicineandman.com%2Fblog%2F2008%2F11%2F13%2Fangioplasty-and-bypass-surgery-education-videos%2F'; addthis_title = 'Angioplasty+and+Bypass+Surgery+education+videos'; addthis_pub = ''; (Source: Medicine and Man) Medicine and Man blogs http://www.medworm.com/rss/comments.php?id=1960815 Fri, 14 Nov 2008 01:05:29 +0100 1960815 http://www.medworm.com/index.php?rid=1891914&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F10%2F20%2Ftreatment-of-heart-attack-national-guidance-final-report-of-the-national-infarct-angioplasty-project-niap%2F Prefaced in the weekends media, the National Infarct Angioplasty Project (NIAP) is a feasibility study looking at how far primary angioplasty can be rolled out as the main treatment for heart attack in place of clot-busting drugs.  Treatment of heart attack national guidance: final report of the National Infarct Angioplasty Project (NIAP) concludes, it is feasible to roll out primary angioplasty for the majority of England within acceptable treatment times and is being published to encourage best practice. Posted in Grey Literature, Heart Diseases, NHS, Surgery   Tagged: Angioplasty, Clinical Guidelines, Grey Literature, Heart Diseases, Myocardial Infarction, NHS, Surgery    (Source: Fade Library) Fade Library blogs http://www.medworm.com/rss/comments.php?id=1891914 Mon, 20 Oct 2008 14:12:53 +0100 1891914 http://www.medworm.com/index.php?rid=1802761&cid=t_161714_105_f&fid=35048&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FMedicineAndMan%2F%7E3%2F394728779%2F Bisphenol A (BPA) has been suspected of being toxic since 1930 when it was found to disrupt the hormones in rats. Now 78 years later, JAMA has published a study which lends further support to the toxic effects of BPA. The first major epidemiological study of bisphenol A, a common ingredient in baby bottles and drink containers, suggests that relatively higher doses of the chemical double the risk of diabetes and cardiovascular disease. Reference: Science Bisphenol A is used extensively in epoxy resins lining food and beverage containers and as a monomer in polycarbonate plastics in many consumer products. Widespread and continuous exposure to BPA, primarily through food but also through drinking water, dental sealants, dermal exposure, and inhalation of household dusts, is evident from... Medicine and Man blogs http://www.medworm.com/rss/comments.php?id=1802761 Wed, 17 Sep 2008 03:27:09 +0100 1802761 http://www.medworm.com/index.php?rid=1773247&cid=t_161714_105_f&fid=35048&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FMedicineAndMan%2F%7E3%2F385961864%2F Chest comes in many varieties! For the purpose of developing heart attack there are 3 criteria that need to be considered: Description - Has 2 sub criteria:- Location - Central chest pain with radiation typically to the left shoulder (although radiation may occur to the right shoulder, neck and jaw) Quality - crushing, band like around chest, heavy as if somebody is sitting on the chest Precipitating factors - Classically precipitated by activity which is reproducible (i.e. walking 2 blocks every time will result in chest pain) Relieving factors - The pain is relieved by rest or nitroglycerin (the pain goes away within 5-10 minutes after taking nitroglycerin, if it takes longer, pain relief is not due to nitroglycerin and will not be considered a relieving factor) (Picture taken fr... Medicine and Man blogs http://www.medworm.com/rss/comments.php?id=1773247 Sun, 07 Sep 2008 18:19:45 +0100 1773247 http://www.medworm.com/index.php?rid=1733979&cid=t_161714_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D4213 A great video that “tells it like it is” the symptoms of a heart attack. It is imperative that anyone suffering from a heart attack receive treatment as soon as possible. This means getting very quickly to a hospital with CCU facilities. Don’t dilly dally. If possible, pop an aspirin on the way. Pre-hospital treatment in the ambulance with other anti-platelet agents may be beneficial e.g. in STEMI. (originally via Dr Wes) Remember: Time is myocardium a Heart attack (VIDEO) (Source: Malaysian Medical Resources) Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=1733979 Tue, 26 Aug 2008 04:00:00 +0100 1733979 http://www.medworm.com/index.php?rid=1709157&cid=t_161714_87_f&fid=34935&url=http%3A%2F%2Fmedicine.com.my%2Fwp%2F%3Fp%3D4109 Prehospital treatment with tirofiban plus standard anti-platelet therapy improves clinical outcomes in patients with ST-elevation myocardial infarction (STEMI), according to research published in The Lancet Looks like just getting aspirin in at the first signs of a heart attack is not enough! a Tirofiban Plus Standard Anti-Platelet Therapy Beneficial for STEMI Patients (Source: Malaysian Medical Resources) Malaysian Medical Resources blogs http://www.medworm.com/rss/comments.php?id=1709157 Fri, 15 Aug 2008 04:00:00 +0100 1709157 http://www.medworm.com/index.php?rid=1563960&cid=t_161714_105_f&fid=35048&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FMedicineAndMan%2F%7E3%2F325390941%2F More conundrums on whether cardiac catheterization is safe for unstable angina (”near heart attack”) or non-ST elevation myocardial infarction (”small heart attacks”). Heart disease is the number one killer of women each year in the United States. Cardiac catheterization is a routine procedure that allows doctors to find potential blockages in coronary arteries in order to help prevent new heart attacks and even death. A recent study finds that high risk women, who do have a heart attack, benefit from this procedure just as much as men. But for some women the procedure may not always be the best option. Reference: JAMA addthis_url = 'http%3A%2F%2Fmedicineandman.com%2Fblog%2F2008%2F07%2F02%2Fcardiac-catheterization-in-women%2F'; addthis_title = 'Cardiac+Cath... Medicine and Man blogs http://www.medworm.com/rss/comments.php?id=1563960 Thu, 03 Jul 2008 02:19:05 +0100 1563960 http://www.medworm.com/index.php?rid=1546568&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2008%2F06%2F26%2F714%2F from the Myocardial Ischaemia National Audit Project (MINAP) finds that MINAP has collected data for eight years (2000–2008), and since it started has accumulated data on over 607,000 patients. It now receives data from all but one hospital that admit heart attack patients in England and Wales. Increased survival from heart attacks has occurred against a background of faster thrombolytic treatment in hospital, the introduction of pre-hospital thrombolysis and primary angioplasty and the improved use of secondary prevention medication. While there is variation between hospitals, most patients with heart attack are treated sooner after calling for professional help than in 2006/7. The use of secondary prevention medication has continued to exceed the national standards. The early... Fade Library blogs http://www.medworm.com/rss/comments.php?id=1546568 Thu, 26 Jun 2008 09:32:42 +0100 1546568 http://www.medworm.com/index.php?rid=1263473&cid=t_161714_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F242443249%2F French researchers announced a striking 15% decrease in admissions of patients with myocardial infarction to emergency wards since the public ban on smoking came into effect in restaurants, hotels and casinos in France last January. This is great news indeed! It just proves further that smoking cessation saves lives. This has also aided in lowering pollution indoors and in outdoor cafes in and around France. Do you think there will be similar results as more bans are in place? Time will tell. via Eurek Alert- European Society of Cardiology Tags: france, heart-attack, myocardial infarction, smoking banShare This (Source: A Hearty Life) A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=1263473 Thu, 28 Feb 2008 01:55:13 +0100 1263473 http://www.medworm.com/index.php?rid=1091279&cid=t_161714_86_f&fid=36669&url=http%3A%2F%2Ffadelibrary.wordpress.com%2F2007%2F12%2F13%2Fcks-is-not-just-for-christmas-but-you-never-thought-it-was%2F The following Prodigy guidance have been reviewed and converted to the Clincal Khowledge Summaries (CKS) format Asthma Conjunctivitis — infective Gingivitis and periodontitis Herpes simplex — oral MI—secondary prevention If you’re not familiar with Clinical Knowledge Summaries, they are concise summaries on the management of 500 commonly encountered scenarios in primary and first-contact care, based on the latest evidence on common acute and chronic diseases and disease prevention. CKS can be accessed from the National Library for Health via your Athens password (register here if you work in the NHS in the North West). If you need any training in using this or any other electronic resources and you work for Liverpool PCT, contact us using the form below. [contact-form] (Sourc... Fade Library blogs http://www.medworm.com/rss/comments.php?id=1091279 Thu, 13 Dec 2007 08:47:13 +0100 1091279 http://www.medworm.com/index.php?rid=1084321&cid=t_161714_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F198083708%2F Here are some links of new publications. All are ideas revisited by me from over the last few months. I read through a lot, and I mean a lot, of science journals and such this morning but the ones that I found the most interesting and news worthy were very similar to research I have shared previous. The new research takes things a step further… Depression linked to death following heart attack…Depression nearly triples the risk of death following a heart attack, even when accounting for other heart attack risk factors, according to research presented today at the American College of Neuropsychopharmacology (ACNP) annual meeting, which showed that among 360 depressed, post myocardial infarction patients followed for more than six years, those who did not recover from their depre... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=1084321 Mon, 10 Dec 2007 14:49:32 +0100 1084321 http://www.medworm.com/index.php?rid=1005311&cid=t_161714_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F180327808%2F Pretty big stuff to report. Researchers out of Wake Forest, National Institute of Health as well as other institutions have discovered a previously undetected chemical process within the oxygen carrying molecule hemoglobin that could have huge implications for cardiovascular disease. Just what does hemoglobin do anyway? In the bloodstream, iron-rich hemoglobin consumes, on contact, any free nitric oxide released by the blood vessels, so the idea that hemoglobin participates in forming nitric oxide had seemed implausible until recently. Basically…hemoglobin is the iron rich oxygen transport protein in the red blood cells. That is the easiest way I know to explain it but you could always Google if you feel the need, haha. But seriously, this new implication for this mighty little molec... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=1005311 Tue, 06 Nov 2007 01:57:08 +0100 1005311 http://www.medworm.com/index.php?rid=927971&cid=t_161714_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F165447073%2F Heart disease of the left main coronary artery has been found to be an inherited condition. Families tend to “share” this form of heart disease. “In our study we focused on the coronary disease pattern underlying coronary artery disease and found that, for left main coronary artery disease, 49 percent of the phenotypic variation that is due to genetic effects was inherited. This substantial heritability is even higher than that for coronary artery disease or myocardial infarction in general.” Why is this important? It can provide for more intensive screening and treatment strategies for patients that have known heart disease clumped in their family. It really does offer some very important clinical implications. Let’s hope we can pinpoint even more aspects of ... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=927971 Thu, 04 Oct 2007 23:39:35 +0100 927971 http://www.medworm.com/index.php?rid=718038&cid=t_161714_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F07%2F06%2Fif-a-heart-attack-happens-are-you-prepared%2F Filed under: Women Heart Health, Men Heart Health, Aging Heart HealthHeart attacks are the #1 cause of death for Americans, and although we spend a lot of time and energy on trying to avoid them, some of us will inevitably still go through the experience -- are you prepared? Whether it's for yourself or someone close to you, do you know what to look for and are you ready to take action? All too often people take much too long to seek treatment, usually because they fail to recognize the symptoms or just don't want to believe it's happening. And heart attacks can't wait -- every second counts! Click here for a review of the basic symptoms to watch for (pressure in the chest, squeezing pain, shortness of breath, feeling of lightheadedness) and what to do if you at all suspect a heart attack ... The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=718038 Fri, 06 Jul 2007 04:00:00 +0100 718038 http://www.medworm.com/index.php?rid=659344&cid=t_161714_132_f&fid=35624&url=http%3A%2F%2Fsuicyte.wordpress.com%2F2007%2F06%2F05%2Fsoul-searching-iii%2F This is the third post of my mini-series on the common susceptibility region for coronary heart disease (CHD) and type 2 diabetes (T2D) on human chromosome 9p21.3. If you have missed the previous parts, they can be found here: I and II. We have seen previously that the authors of the CHD papers have mapped the risk region for coronary heart disease to a short interval of 58 kb, which contains the three SNPs with the strongest risk association (rs1333040, rs2383207 and rs10116277). One of the papers cites HapMap data arguing that this region is part of a larger 190 kb linkage block. I don’t quite understand why this should be relevant though; both groups have tested lots of SNPs within this 190 kb block, all of them showing much weaker association (if any) to the disease risk. This me... Suicyte Notes blogs http://www.medworm.com/rss/comments.php?id=659344 Tue, 05 Jun 2007 22:37:15 +0100 659344 http://www.medworm.com/index.php?rid=658879&cid=t_161714_87_f&fid=34866&url=http%3A%2F%2Fwww.thecardioblog.com%2F2007%2F06%2F04%2Fmission-lifeline-to-battle-the-deadliest-heart-attacks%2F Filed under: American Heart AssociationThe deadliest form of heart attack, which involves total blockage of a heart artery and is called an ST-elevation myocardial infarction (STEMI), is hopefully about to get a little less deadly. The American Heart Association is planning to launch a new community-based program called "Mission Lifeline" specifically designed to improve treatment times for patients suffering from this type of heart attack. The plan will focus both on teaching patients to recognize the symptoms of a heart attack sooner and call 911, and on establishing reliable speedy systems to transport the patients in need to appropriately equipped hospitals.Read | Permalink | Email this | Linking Blogs | Comments (Source: The Cardio Blog) The Cardio Blog blogs http://www.medworm.com/rss/comments.php?id=658879 Mon, 04 Jun 2007 04:00:00 +0100 658879 http://www.medworm.com/index.php?rid=645627&cid=t_161714_132_f&fid=35624&url=http%3A%2F%2Fsuicyte.wordpress.com%2F2007%2F05%2F28%2Fsoul-searching-ii%2F In the previous part of this mini-series, I had a closer look at the boundaries for the 9p21.3 risk interval for coronary heart disease (CHD) . Today, I will do the same for the type 2 diabetes (T2D) risk associated with the same chromosome region. The first paper (out of three) describes joint work from the Broad Institute, Lund University and the Novartis Institutes. Similar to the CHD papers discussed yesterday, the authors start with a genome-wide SNP-bases association study , using 386,731 different SNPs and case- and control-groups of almost 1500 subjects each. This looks like a lot of work. After the usual filtering and confirmation experiments, the authors describe novel associations to three different loci: one SNP in the 9p21.3 region near CDKN2A/2B, one in an intron of IGF2BP2, ... Suicyte Notes blogs http://www.medworm.com/rss/comments.php?id=645627 Mon, 28 May 2007 00:35:03 +0100 645627 http://www.medworm.com/index.php?rid=639756&cid=t_161714_132_f&fid=35624&url=http%3A%2F%2Fsuicyte.wordpress.com%2F2007%2F05%2F26%2Fsoul-searching-i%2F Sorry for the delay in starting this mini-series. My job has kept me more busy than I expected, and what I am trying to do here requires a lot of free time, which is currently a very limited resource. Just a brief reminder: in a recent post, I discussed a series of papers (pre-)published in Science, which link the susceptibility to myocardial disease and type 2 diabetes to a common region on human chromosome 9p21.3. Francis Collins has likened this region to the “soul of the genome”, and is this soul that I am going to search for. The effort will be documented here on this blog, and you are all invited to advise me or correct me by using the comment function. In this first part of the series, I will analyze in somewhat more detail what the papers say about the limits of the cri... Suicyte Notes blogs http://www.medworm.com/rss/comments.php?id=639756 Sat, 26 May 2007 12:51:23 +0100 639756 http://www.medworm.com/index.php?rid=639758&cid=t_161714_132_f&fid=35624&url=http%3A%2F%2Fsuicyte.wordpress.com%2F2007%2F05%2F15%2Fsoul-searching-announcement%2F I plan to do an experiment in science blogging. As my may have noticed, an earlier post on this blog addresses a series of recent papers identifying markers with strong association to both myocardial infarction risk and type 2 diabetes. Both markers map to a narrow region on 9p21.3. In an interview, Francis Collins compared this region to the ’soul of the genome’, which many people thought was kind of funny. Nevertheless, there is little doubt that something interesting is going on in this part of the genome. Since I am a generally curious person, I am going to have a closer look at 9p21.3, and I am sure that many other people will do so. Unlike the others, I am going to describe my work, ideas and results in a series of blog posts, here on Suicyte Notes. If anybody else wants ... Suicyte Notes blogs http://www.medworm.com/rss/comments.php?id=639758 Tue, 15 May 2007 20:14:53 +0100 639758 http://www.medworm.com/index.php?rid=639760&cid=t_161714_132_f&fid=35624&url=http%3A%2F%2Fsuicyte.wordpress.com%2F2007%2F05%2F11%2Fheart-and-soul-and-diabetes%2F There is one fundamental question that has been nagging on me since grad school: Where is the seat of the soul in the human genome? Thanks to the relentless search of several groups of scientists [1, 2, 3, 4, 5] , with some help from Francis Collins, we now know the answer: it resides on chromosome 9p21. This is what we learn when reading an article by Nicholas Wade in the online version of The New York Times. This topic also has been blogged before, on The Tree of Life and on iBiome. Here is some background: Myocardial infarction and type 2 diabetes are unrelated multifactorial diseases that are thought to have a genetic component. Since both conditions are severe and quite common, many groups are out to find so-called susceptibility genes, these are gene variants that have a marked influ... Suicyte Notes blogs http://www.medworm.com/rss/comments.php?id=639760 Fri, 11 May 2007 22:42:03 +0100 639760