MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'interferon'. Sat, 03 Sep 2011 02:09:33 +0100 http://www.medworm.com/index.php?rid=4636109&cid=t_111302_139_f&fid=38879&url=http%3A%2F%2Ftraffic.libsyn.com%2Ftwiv%2FTWiV121.mp3 Hosts: Vincent Racaniello, Michael Katze, Michael Gale, Deborah Fuller, and Shawn Iadonato Episode #121 of the podcast This Week in Virology is a conversation about careers in virology, systems biology, innate immunity, and antiviral research recorded at the University of Washington in Seattle. Download TWiV #121 (65 MB .mp3, 90 minutes). To download, right-click or control-click on the link, then select save as. Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, or by email, or listen on your mobile device with the Microbeworld app. Links for this episode: A systems biology approach to infectious disease research (mBio) Infectious Curiosity (thanks, Gopal!) Astronomy Cast (thanks, Jacob!) The Journal of Negative Results (thanks, Patricia!) Scientist Solutions... virology blog blogs http://www.medworm.com/rss/comments.php?id=4636109 Sun, 20 Feb 2011 23:23:10 +0100 4636109 http://www.medworm.com/index.php?rid=3672051&cid=t_111302_151_f&fid=35818&url=http%3A%2F%2Frecoveryissexy.com%2Falcohol-and-hepatitis%2F In conclusion alcohol abuse is associated with an accelerated progression of liver injury, leading to an earlier development of cirrhosis, higher incidence of cancer of the liver, and higher death rates. Abstinence from alcohol could reverse some of these deleterious effects. Research report; Gitto S, Micco L, Conti F, Andreone P, Bernardi M. Alcohol and viral hepatitis: a mini-review. Dig Liver Dis. 2009 Jan;41(1):67-70. See also; Hep C Factsheet Hepatitis B If you have healthcare training this manual may help. Hazelden Books and Categories Faith It Till You Make It Recovery Books, Medallions & DVD's (Source: Recovery Is Sexy.com) Recovery Is Sexy.com blogs http://www.medworm.com/rss/comments.php?id=3672051 Thu, 17 Jun 2010 16:13:00 +0100 3672051 http://www.medworm.com/index.php?rid=3193805&cid=t_111302_111_f&fid=36048&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FAHeartyLife%2F%7E3%2F0LUJ4zuNX0s%2F Multiple sclerosis is a neurological disease that strikes most often in adults who are just getting going with their life – they’re establishing their careers, starting families, and they have plans. MS is a disease that can progress slowly, allowing those affected by it to live fairly “normal” lives. Unfortunately, others deteriorate quickly to the point that they can’t care for themselves before they die. MS is seen more in northern countries, so there is a theory that sunlight – or lack of sunlight – plays a role in the development of the disease. Canada has the dubious distinction of having the highest rate of MS in the world. What MS Is In MS, the nerves in the central nervous system (CNS), which is made up of the brain and spinal cord, degene... A Hearty Life blogs http://www.medworm.com/rss/comments.php?id=3193805 Thu, 21 Jan 2010 15:53:03 +0100 3193805 http://www.medworm.com/index.php?rid=3044889&cid=t_111302_129_f&fid=36038&url=http%3A%2F%2Fwww.everydayhealth.com%2Fblog%2Ftrevis-life-with-multiple-sclerosis-ms%2Fhalt-ms-and-stem-cell-research%2F My wife, Caryn and I were talking the other day about my next options for MS disease modifying therapies. As many of you know, interferon treatments are out for me.  Copaxone is prohibitively expensive (and because of Medicare Part B, I am not eligible for drug company assistance) and I’ve used my lifetime maximum of Novantrone.  That would seem to leave Tysabri as our only (FDA approved) option. Then we started talking about the HALT-MS (high-dose immunosuppression and autologous stem cell transplantation for MS) study as a possible option.  HALT-MS is an experimental treatment for multiple sclerosis which is showing some very impressive results. The problem is…well the problems are many.  The first problem was that I didn’t know as much about the treatment as I should! I ma... Life with MS blogs http://www.medworm.com/rss/comments.php?id=3044889 Mon, 30 Nov 2009 22:40:07 +0100 3044889 http://www.medworm.com/index.php?rid=2886210&cid=t_111302_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F10%2Finfluenza-non-structural-protein-1.html The non-structural protein 1 (NS1) of influenza virus is a potent antagonist of the cellular antiviral interferon (IFN) response. It is a multifunctional protein with two domains, a dsRNA binding domain (RBD) and an effector domain (ED) which interacts with various cellular proteins. Although, initially sequestration of dsRNA was considered the primary mechanism for countering IFN, subsequent studies have shown that the interactions of ED with various cellular proteins are likely involved. NS1 is shown to be a virulence determinant, especially in the highly pathogenic H5N1 viruses that are currently a threat for another influenza pandemic. Among various influenza virus strains, NS1 is relatively well conserved with major differences occurring in the linker region and the C-terminus, where... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2886210 Mon, 12 Oct 2009 15:34:00 +0100 2886210 http://www.medworm.com/index.php?rid=2868674&cid=t_111302_77_f&fid=37259&url=http%3A%2F%2Fwww.horizonpress.com%2Fblogger%2F2009%2F10%2Frnai-gene-therapy-to-control-hepatitis.html Hepatitis C virus (HCV) is a leading cause of chronic hepatitis and its sequels, end-stage liver disease and hepatocellular carcinoma, are the most common indications for liver transplantation. The current standard treatment, pegylated-interferon-alpha in combination with ribavirin, represents a milestone in therapy, but only eradicates the virus in half of the patients, leaving tens of millions without hope for a cure. Therefore, it is urgent to explore novel and more effective therapeutic options. Such advancements could be derived from a better understanding of HCV biology. Progress in this area has accelerated with the application of RNA interference (RNAi) as a discovery tool to investigate viral and host cell factors involved in viral infection. Furthermore, RNAi has high potential a... Microbiology Blog: The weblog for microbiologists. blogs http://www.medworm.com/rss/comments.php?id=2868674 Wed, 07 Oct 2009 15:30:00 +0100 2868674 http://www.medworm.com/index.php?rid=3016947&cid=t_111302_139_f&fid=38879&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2FVirologyBlog%2F%7E3%2FB_kwBKpERVk%2F During a discussion about blogging on the Coast to Coast Bio Podcast, it was suggested that science professors should spend more time writing about their research – by explaining what problems they are trying to solve, how they approach them, and why they are interesting. My goal here at virology blog is mainly to teach virology. But explaining what we do in my virology laboratory can be an effective instructional tool. About five years ago I became very interested in the innate immune response to viral infections. The innate response is considered the first line of immune defense because it is active even before infection begins. Many viral infections are halted by the innate immune system, which responds very quickly – within minutes to hours after infection. The key to innate de... virology blog blogs http://www.medworm.com/rss/comments.php?id=3016947 Fri, 18 Sep 2009 12:00:56 +0100 3016947 http://www.medworm.com/index.php?rid=2712221&cid=t_111302_122_f&fid=34755&url=http%3A%2F%2Fneuropsychological.blogspot.com%2F2009%2F08%2Fbusiness-world-novartis-multiple.html From The Wall Street Journal's Health Blog:AUGUST 17, 2009, 11:12 AM ETNovartis’s Big Plans for Multiple SclerosisBy Jeanne Whalen[snippet]The FDA gave Novartis the green light today to start selling a copy of Betaseron, the multiple sclerosis drug long sold by Bayer.Why would Novartis want to sell somebody else’s years-old drug? Largely to gain experience in the MS marketplace as Novartis plots a future launch of the MS drug FTY720.“It’s a way to build a strong commercial organization and a strong medical organization ahead of FTY,” Novartis pharmaceuticals chief Joe Jimemez told the Health Blog recently.[snippet]Read the full blog entry==========Note: Here is a reference to FTY720:Horga A, & Montalban X. (2008). FTY720 (fingolimod) for relapsing multiple sclerosis. Expert Rev N... BrainBlog blogs http://www.medworm.com/rss/comments.php?id=2712221 Tue, 18 Aug 2009 21:40:00 +0100 2712221 http://www.medworm.com/index.php?rid=2227636&cid=t_111302_129_f&fid=36038&url=http%3A%2F%2Fwww.everydayhealth.com%2Fblog%2Ftrevis-life-with-multiple-sclerosis-ms%2Fviewing-an-ms-lesion-up-close-and-personal%2F Last week, I was invited to attend a meeting of the Washington Biotechnology and Biomedical Association (WBBA), a trade organization of some very bright minds. The evening’s topic was, as you would guess, multiple sclerosis. The panel consisted of a well respected local MS specializing neurologist, a representative of a small bio/pharma company which is studying the next generation of Interferon drugs for multiple sclerosis and the Medical Director of the Swedish Neuroscience Institute. Information passed along at the meeting was comprehensive and very interesting. I’m still pouring over my copies of the PowerPoint slides for future blog topics. One thing, however, struck me so completely that I thought I’d share it with you this Monday. I saw an MS lesion. Now, I know we’ve all se... Life with MS blogs http://www.medworm.com/rss/comments.php?id=2227636 Mon, 02 Mar 2009 21:38:27 +0100 2227636 http://www.medworm.com/index.php?rid=2019567&cid=t_111302_117_f&fid=38204&url=http%3A%2F%2Fprofjelinek.medbrains.net%2F2008%2F11%2Fholistic-management-of-ms%2F Dr Craig Hassed, well known Monash University academic, and author of the books ‘Know Thyself: The Stress Release Programme”, “New Frontiers in Medicine: The Body as the Shadow of the Soul”, and the recent bestseller “The Essence of Health”, has published a very good online summary of the optimal management of MS. Visit  http://www.mindfood.com/at-mag-wellbeing-condition-multiple-sclerosis.seo New Frontiers [...] (Source: Achieving Optimal Health) Achieving Optimal Health blogs http://www.medworm.com/rss/comments.php?id=2019567 Sat, 08 Nov 2008 02:59:59 +0100 2019567 http://www.medworm.com/index.php?rid=1052558&cid=t_111302_109_f&fid=35671&url=http%3A%2F%2Fwww.anxietyinsights.info%2Ffda_recommends_additional_neuropsychiatric_warnings_for_infl.htm According to a media report, staff at the FDA are recommending that new warnings regarding psychiatric adverse events be added to the US labels for oseltamivir (Tamifluont ®) and zanamivir (Relenza®). Although similar concerns with oseltamivir were first raised two years ago following twelve reported cases of fatalities in Japan, the FDA concluded at that time that there was insufficient evidence for a causal association with the drug. The FDA did however add a caution to the US oseltamivir label urging that patients be closely monitored for abnormal behavior, such as delirium or self-injury. In the current review, FDA staff have looked at 596 cases of neuropsychiatric events linked to oseltamivir (75% of which occurred in Japan), including five reports of delirium in pediatric pat... Latest entries from www.anxietyinsights.info blogs http://www.medworm.com/rss/comments.php?id=1052558 Tue, 27 Nov 2007 08:17:00 +0100 1052558 http://www.medworm.com/index.php?rid=650892&cid=t_111302_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F06%2F01%2Finterferon-may-improve-survival-in-advanced-liver-cancer%2F Filed under: Drug, Liver Cancer, Research, SurgeryInterferon is an immune stimulating agent. According to an article recently published in the Annals of Surgery, administration of interferon following surgery may improve survival among patients with advanced hepatitis B-related hepatocelluar carcinoma. Hepatocelluar carcinoma (HCC) is the most common type of liver cancer. Unfortunately for this disease, recurrences often happen after surgical removal of the cancer. Researchers continue to evaluate ways to reduce these recurrences. A clinical trial was conducted to evaluate the use of interferon following surgery in patients with HCC. The trial included 80 patients, one group received the interferon after surgery and the other group received no further treatment. The researchers found that ... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=650892 Fri, 01 Jun 2007 04:00:00 +0100 650892 http://www.medworm.com/index.php?rid=536614&cid=t_111302_87_f&fid=34865&url=http%3A%2F%2Fwww.thecancerblog.com%2F2007%2F04%2F11%2Ffda-needs-more-time-with-wyeth-kidney-cancer-drug%2F Filed under: Drug, Research, Daily newsThe Food and Drug Administration (FDA) will take an additional three months to review Wyeth's kidney cancer drug Torisel -- the first of five new medications the company plans to introduce this year.The FDA needs more time to investigate data on tumor growth in patients taking Torisel. If all goes well, the drug will be one of only three to effectively hold off incurable kidney cancer. The other two drugs are Pfizer's Sutent and Bayer AG's Nexavar.Robert Ruffolo, president of Wyeth Research, says he is encouraged by the review process so far. And he is optimistic about launching the product in late 2007.Studies show Torisel, which will cost patients about $30,000 per year, prolonged survival by 50 percent in those faring poorly with kidney cancer. The... The Cancer Blog blogs http://www.medworm.com/rss/comments.php?id=536614 Wed, 11 Apr 2007 04:00:00 +0100 536614