MedWorm provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest medical blog items that have been tagged with 'interleukin'. Sat, 03 Sep 2011 02:22:29 +0100 http://www.medworm.com/index.php?rid=4433289&cid=t_155859_136_f&fid=37846&url=http%3A%2F%2Fhealthinfoispower.wordpress.com%2F2011%2F02%2F03%2Ffda-awards-1-6m-orphan-drug-grant-for-clinical-phase-ii-development-of-egen-001-for-treatment-of-ovarian-cancer%2F EGEN, Inc. announced that the Food and Drug Administration (FDA) awarded the company a four-year grant of $1.6 million to assist in the phase II clinical development of EGEN-001, the company’s lead product. EGEN-001 is under clinical development for the treatment of advanced recurrent ovarian cancer. EGEN, Inc. announced that the Food and Drug Administration (FDA) [...] (Source: Libby's H*O*P*E*) Libby's H*O*P*E* blogs http://www.medworm.com/rss/comments.php?id=4433289 Thu, 03 Feb 2011 21:52:52 +0100 4433289 http://www.medworm.com/index.php?rid=2876251&cid=t_155859_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FwUSQad178nc%2F This may sound like a sales pitch, but it’s not. If you’re having problems with your memory, or you want to improve it, then you might want to closely follow the research from this German team  of scientists. Published in the journal for experimental biology (FASEB Journal), German scientists discovered that administering a nasal spay containing interleukin-6 improved the memory of it subjects! According to the paper, Interleukin-6 exerts “neuromodulating influences on the brain, with promoting influences on sleep”. The researchers hypothesized that IL-6 could help consolidate our memories better during sleep, so they administered a nasal spray of IL-6 to test subjects after they read several short stories before bed. The control and test subjects slept and, the next morning... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2876251 Fri, 09 Oct 2009 16:31:00 +0100 2876251 http://www.medworm.com/index.php?rid=2857335&cid=t_155859_146_f&fid=38266&url=http%3A%2F%2Fsleepeducation.blogspot.com%2F2009%2F10%2Fsleep-memory-can-nasal-spray-help-you.html German researchers have tested how a unique nasal spray affects sleep and memory.The study involved a nasal spray containing “interleukin-6.” IL-6 is a cytokine; it is a signaling molecule that transmits information between cells. Seventeen young men spent two nights in a lab, reports a FASEB Journal statement. Each time they read either an emotional or neutral short story. Then they were given either the IL-6 nasal spray or a placebo spray.Declarative memory was tested in the morning after a night of sleep. Participants wrote down as many words as they could remember from the story.Results show that IL-6 distinctly improved the sleep-related consolidation of emotional text material; participants who received the dose of IL-6 could remember more words from the emotional story. The auth... Sleep Education blogs http://www.medworm.com/rss/comments.php?id=2857335 Sat, 03 Oct 2009 10:20:00 +0100 2857335 http://www.medworm.com/index.php?rid=2834387&cid=t_155859_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2Fi_yQInvwMsY%2F This latest FDA approval would bring relief to more than 7.5 million Americans who suffer from a chronic skin disorder called PSORIASIS, which look like red, thick, scaly patches on the skin. Psoriatic patches, which are usually itchy and painful, are inflamed areas where excessive layers of cells had built up on the skin. And now, after extensive and extended testing, the FDA has approved ustekinumab (Stelara) for moderate to severe plaque psoriasis. (See amazing before-and-after photos!) Psoriasis is an auto-immune disease, which means a faulty immune system mistakenly attacks the skin and joints, treating the body like an invader and releasing chemicals that otherwise fight infections and foreign substances. As bad as it already looks, psoriasis affects more than the skin. The dis... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2834387 Sat, 26 Sep 2009 03:56:00 +0100 2834387 http://www.medworm.com/index.php?rid=2458375&cid=t_155859_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FRdUHmqA3XeA%2F My heart breaks when I see photos of children suffering from genetic disorders, such as the nine babies from this story. But this story also lauds to the use of genetically modified organisms for producing drugs for treatment. Recently, scientists discovered a new genetic disorder in nine newborn to 2-week old babies. The infants had swollen bone tissues, bone pain and deformity, and rashes that can range in size from small fluid-filled blisters or pustules to blisters that covered the whole body. The researchers immediately realized they were looking at an unrecognized auto-inflammatory syndrome, where recurring episodes of inflammation occur without any pathogens or immune cells triggering the reaction. All nine babies had mutations of IL1RN, a gene involved in the immune response whic... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2458375 Fri, 05 Jun 2009 20:34:11 +0100 2458375 http://www.medworm.com/index.php?rid=2313445&cid=t_155859_109_f&fid=35671&url=http%3A%2F%2Fwww.anxietyinsights.info%2Fabstract_higher_plasma_interleukin6_il6_level_is_associ.htm Prog Neuropsychopharmacol Biol Psychiatry. 2009 Mar 28;doi:10.1016/j.pnpbp.2009.03.020Higher plasma interleukin-6 (IL-6) level is associated with SSRI- or SNRI-refractory depression Yoshimura R, Hori H, Ikenouchi-Sugita A, Umene-Nakano W, Ueda N, Nakamura J. Department of Psychiatry, University of Occupational and Environmental Health, School of Medicine, 1-1 Iseigaoka, Yahatanishi-ku, Kiatkyushu8078555, Japan In the present study, we compared plasma levels of interleukin-6 (IL-6), tumor necrosis factor-a (TNFa), and brain-derived neurotrophic factor (BDNF) among selective serotonin reuptake inhibitor (SSRI)-or serotonin noradrenaline reuptake inhibitor (SNRI)-responsive depressed patients (n = 31), SSRI-or SNRI-refractory [treatment resistant, ed] depressed patients (n = 20), and healthy ... Latest entries from www.anxietyinsights.info blogs http://www.medworm.com/rss/comments.php?id=2313445 Fri, 03 Apr 2009 07:21:00 +0100 2313445 http://www.medworm.com/index.php?rid=2011175&cid=t_155859_131_f&fid=34989&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FGeneticsHealth%2F%7E3%2FVMF5FyX4uzs%2F This new study is along the lines of vaccine-producing bananas. One of the best uses of genetic engineering of plants is producing rare proteins with medical use in larger quantities. Interleukin-12 is one of those proteins that our bodies produce in regulated quantities, but is very essential for the function of the immune system. Certain immune diseases are the result of having either too little or too much interleukin-12. If scientists can harness enough of the protein for research and therapeutic development, then perhaps certain diseases can be controlled better. New findings published in the journal Biotechnology and Bioengineering found a way for interleukin-12 to be produced artificially inside genetically-modified tobacco in a more efficient way using nutrient mist bioreactors. ... Genetics and Health blogs http://www.medworm.com/rss/comments.php?id=2011175 Thu, 04 Dec 2008 06:49:51 +0100 2011175 http://www.medworm.com/index.php?rid=1689177&cid=t_155859_109_f&fid=35671&url=http%3A%2F%2Fwww.anxietyinsights.info%2Fthe_effects_of_stress_hormones_on_neurotransmission.htm Laboratoire Physiologie Cellulaire de la Synapse and Neurocentre Inserm researchers, working at the NeuroCampus of the Université de Bordeaux, France, have discovered how the stress hormone cortisol regulates brain neurotransmission on the short and long term and enables neuronal connections to adapt. The research, directed by Laurent Groc and Francis Chaouloff, may lead to the identification of new therapeutic targets for psychiatric illnesses such as post-traumatic stress disorder and depression. When we are subjected to a stress, our adrenal glands secrete hormones that affect our entire body. One of these hormones, cortisol, enables us to adapt physically and mentally to the stimulus. With a major or repeated stress that an individual has no control over, however, cortisol is se... Latest entries from www.anxietyinsights.info blogs http://www.medworm.com/rss/comments.php?id=1689177 Fri, 08 Aug 2008 08:58:00 +0100 1689177 http://www.medworm.com/index.php?rid=1683524&cid=t_155859_136_f&fid=36051&url=http%3A%2F%2Ffeeds.b5media.com%2F%7Er%2Fb5media%2FCancerCommentary%2F%7E3%2FPbkU2BRxEJg%2F A research team from Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have showed that combining a dietary agent with a gene-delivered cytokine effectively eliminates human pancreatic cancer cells in mice displaying sensitivity to these highly aggressive and lethal cancer cells. The cytokine used in this study was melanoma differentiation associated gene-7/interleukin-24, known as mda-7/IL-24. The dietary agent, perillyl alcohol (POH), was combined with mda-7/IL-24, which is already used in other cancer treatments. POH is found in a variety of plants, including citrus plants, and has been well-tolerated by patients who have received it in clinical studies. Published in the July issue of Molecular Cancer Therapeutics, their results indicated ... Cancer Commentary blogs http://www.medworm.com/rss/comments.php?id=1683524 Tue, 05 Aug 2008 23:07:29 +0100 1683524 http://www.medworm.com/index.php?rid=1446423&cid=t_155859_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F291591536%2F Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us and we’ll share with it others. That’s right. Send us your announcements and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going, especially with all the layoffs being announced each month. Despite downsizing, there is movement. Here are some of the latest changes. Recognize anyone? Celator Pharmaceuticals hired Scott Jackson as its new ceo; Albireo hired Hans Graffner as chief medical officer; Fate Therapeutics hired Paul Grayson as ceo and president; Fate Therapeutics also hired John Mendlein as chairman; Eurotherm named Steve Blomquist president of Eurotherm USA; MacroGenics hired Jean-Christophe Tellier as exec vp and chief c... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=1446423 Fri, 16 May 2008 11:56:19 +0100 1446423 http://www.medworm.com/index.php?rid=1170199&cid=t_155859_109_f&fid=35671&url=http%3A%2F%2Fwww.anxietyinsights.info%2Fimmune_system_molecule_key_to_stress_triggered_brain_atrophy.htm Acute and chronic stress can have devastating effects on the brain, and Yale School of Medicine researchers have pinpointed one receptor that plays a key role in that harmful cycle, according to a report in the Proceedings of the National Academy of Sciences. "This could provide new targets for the development of antidepressant medications," said Ronald Duman, professor of psychiatry and pharmacology and senior author of the study. Duman said uncontrollable stress is a major contributing factor for neuropsychiatric disorders such as major depression and post-traumatic stress disorders, which have been linked to cellular changes in the hippocampus. The hippocampus regulates emotion and memory storage and is particularly susceptible to stress. But little is known about the underlying mechani... Latest entries from www.anxietyinsights.info blogs http://www.medworm.com/rss/comments.php?id=1170199 Wed, 23 Jan 2008 08:08:00 +0100 1170199 http://www.medworm.com/index.php?rid=1052558&cid=t_155859_109_f&fid=35671&url=http%3A%2F%2Fwww.anxietyinsights.info%2Ffda_recommends_additional_neuropsychiatric_warnings_for_infl.htm According to a media report, staff at the FDA are recommending that new warnings regarding psychiatric adverse events be added to the US labels for oseltamivir (Tamifluont ®) and zanamivir (Relenza®). Although similar concerns with oseltamivir were first raised two years ago following twelve reported cases of fatalities in Japan, the FDA concluded at that time that there was insufficient evidence for a causal association with the drug. The FDA did however add a caution to the US oseltamivir label urging that patients be closely monitored for abnormal behavior, such as delirium or self-injury. In the current review, FDA staff have looked at 596 cases of neuropsychiatric events linked to oseltamivir (75% of which occurred in Japan), including five reports of delirium in pediatric pat... Latest entries from www.anxietyinsights.info blogs http://www.medworm.com/rss/comments.php?id=1052558 Tue, 27 Nov 2007 08:17:00 +0100 1052558 http://www.medworm.com/index.php?rid=1015901&cid=t_155859_109_f&fid=35671&url=http%3A%2F%2Fwww.anxietyinsights.info%2Fabstract_wild_yam_reduces_anxiety_protein_levels.htm Conclusion: These results show that OVX-induced anxiety and changes in neuroimmunological function in the cortex are reversed by dioscorea treatment. Furthermore, individual differences need to be taken into account when psychoneuroimmunological issues are measured and the EPM is a useful tool for determining anxiety levels when examining anxiety-related issues. (Text has been reformatted for clarity; ed.) Source + Full text... Caution:  Some Over-The-Counter (OTC) supplements may interact with prescription medications or be affected by them. Check with your doctor or pharmacist before taking any herbal or OTC supplement while on medication. Most governments do not require dietary supplement makers to demonstrate the safety or effectiveness of their products. Ask your healthcare provi... Latest entries from www.anxietyinsights.info blogs http://www.medworm.com/rss/comments.php?id=1015901 Fri, 09 Nov 2007 07:07:00 +0100 1015901 http://www.medworm.com/index.php?rid=865684&cid=t_155859_150_f&fid=35777&url=http%3A%2F%2Ffeeds.feedburner.com%2F%7Er%2FPharmalot%2F%7E3%2F155473386%2F Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us and we’ll share with it others. That’s right. Send us your announcements and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. Here are some of the latest moves… Synvista Therapeutics appointed John Bedard to its board; Alba Therapeutics named Betsy Van Parijs sr vp, clinical development and medical affairs; Modern Biosciences hired Clive Dix as non-executive chairman; Athersys elected Jeff Randall to its board; Shire named Anita Graham chief admin officer and exec vp of corporate business services; Interleukin Genetics named Tom Gerson as CFO, tapped Jim Weaver as board chair, and hired Nazneen Aziz as R&D vp; Proteon ... Pharmalot blogs http://www.medworm.com/rss/comments.php?id=865684 Wed, 12 Sep 2007 11:29:41 +0100 865684