MedWorm: Laser Therapy

Facial angiofibromas treated with topical rapamycin: An excellent choice with fast response.

Dermatol Online J — Mon, 06 Feb 2012 12:54:18 +0100

We report the 6th case of facial AF treated with topical rapamycin, 1 percent, once per day. An excellent response was achieved surprisingly rapidly. We propose this option as a safe and effective therapy. PMID: 22301052 [PubMed - in process] (Source: Dermatol Online J)

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Transcranial laser therapy for acute ischemic stroke: a pooled analysis of NEST‐1 and NEST‐2

International Journal of Stroke — Thu, 02 Feb 2012 05:00:00 +0100

ConclusionsThis pooled analysis support the likelihood that transcranial laser therapy is effective for the treatment of acute ischemic stroke when initiated within 24 h of stroke onset. If ultimately confirmed, transcranial laser therapy will change management and improve outcomes of far more patients with acute ischemic stroke. (Source: International Journal of Stroke)

Platelet‐Rich Plasma Combined with Fractional Laser Therapy for Skin Rejuvenation

Dermatologic Surgery — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionPRP with fractional laser treatment is a good combination therapy for skin rejuvenation. Keratinocyte and fibroblast proliferation and collagen production can explain the capacity of PRP to increase dermal elasticity. (Source: Dermatologic Surgery)

Therapeutic ultrasound for carpal tunnel syndrome.

Cochrane Database of Systematic Reviews — Thu, 26 Jan 2012 08:18:08 +0100

CONCLUSIONS: There is only poor quality evidence from very limited data to suggest that therapeutic ultrasound may be more effective than placebo for either short- or long-term symptom improvement in people with CTS. There is insufficient evidence to support the greater benefit of one type of therapeutic ultrasound regimen over another or to support the use of therapeutic ultrasound as a treatment with greater efficacy compared to other non-surgical interventions for CTS, such as splinting, exercises, and oral drugs. More methodologically rigorous studies are needed to determine the effectiveness and safety of this intervention for CTS. PMID: 22259004 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)

Photocoagulation of dermal blood vessels with multiple laser pulses in an in vivo microvascular model

Lasers in Surgery and Medicine — Tue, 24 Jan 2012 05:00:00 +0100

ConclusionsThe MLP approach can induce blood vessel photocoagulation at much lower RE per pulse as compared to SLP. The 5 Hz fr and the need for two pulses are achievable with modern laser technology, which makes the MLP approach practical in the clinical management of PWS birthmarks. Lasers Surg. Med. © 2012 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)

Bevacizumab for the Treatment of Retinopathy of PrematurityBevacizumab for the Treatment of Retinopathy of Prematurity

Medscape Today Headlines — Mon, 23 Jan 2012 16:16:35 +0100

How does intravitreal bevacizumab monotherapy compare with conventional laser therapy for the treatment of retinopathy of prematurity? Medscape Ophthalmology (Source: Medscape Today Headlines)

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A Randomized Controlled Trial of Fractional Laser Therapy and Dermabrasion for Scar Resurfacing

Dermatologic Surgery — Mon, 23 Jan 2012 05:00:00 +0100

ConclusionFractionated CO2 laser therapy should be considered a safe alternative for surgical scar resurfacing on the face. The safety profile exceeds that of dermabrasion, and it has a quicker clinical recovery and equivalent cosmetic efficacy. (Source: Dermatologic Surgery)

Time to consider a new treatment protocol for aggressive posterior retinopathy of prematurity?

Acta Ophthalmologica — Mon, 23 Jan 2012 05:00:00 +0100

Conclusions: Given the high complication rate of the extensive laser treatment for zone I ROP, it is worth considering anti‐vascular endothelial growth factor treatment as an alternative therapy. Further knowledge concerning side effects and long‐term ocular and systemic outcome is warranted before this drug becomes general clinical practice. (Source: Acta Ophthalmologica)

Low-Level Laser Therapy Improves Visual Acuity in Adolescent and Adult Patients with Amblyopia

Photomedicine and Laser Surgery — Wed, 11 Jan 2012 17:36:27 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Low Level Laser Therapy (LLLT) and World Association for Laser Therapy (WALT) Dosage Recommendations

Photomedicine and Laser Surgery — Tue, 10 Jan 2012 20:41:34 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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Effect of Adjunctive Low Level Laser Therapy (LLLT) on Nonsurgical Treatment of Chronic Periodontitis

Photomedicine and Laser Surgery — Tue, 10 Jan 2012 20:41:31 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Chronic gingivitis: the prevalence of periodontopathogens and therapy efficiency

European Journal of Clinical Microbiology and Infectious Diseases — Thu, 05 Jan 2012 17:05:22 +0100

Abstract The purpose of this study was to determine the level of gingival inflammation and the prevalence of periodontopathogenic microorganisms in adolescents with chronic gingivitis, as well as to compare the effectiveness of two approaches in gingivitis treatment-basic therapy alone and basic therapy + adjunctive low-level laser therapy (LLLT). After periodontal evaluation, the content of gingival pockets of 140 adolescents with gingivitis was analyzed by multiplex PCR for the presence of P. gingivalis, A. actinomycetemcomitans, T. forsythensis and P. intermedia. Subsequent to bacteria detection, the examinees were divided into two groups with homogenous clinical and microbiological characteristics. Group A was subjected to basic gingivitis therapy, and group B underwent ...

The Effect of 670-nm Low Laser Therapy on Herpes Simplex Type 1

Photomedicine and Laser Surgery — Wed, 04 Jan 2012 15:39:32 +0100

Photomedicine and Laser Surgery Jan 2012, Vol. 30, No. 1: 37-40. (Source: Photomedicine and Laser Surgery)

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Near Infrared Transcranial Laser Therapy Applied at Various Modes to Mice following Traumatic Brain Injury Significantly Reduces Long-Term Neurological Deficits

Journal of Neurotrauma — Wed, 04 Jan 2012 14:34:45 +0100

Journal of Neurotrauma , Vol. 0, No. 0. (Source: Journal of Neurotrauma)

Low‐level laser therapy for closed‐head traumatic brain injury in mice: effect of different wavelengths

Lasers in Surgery and Medicine — Sun, 01 Jan 2012 05:00:00 +0100

ConclusionsThe effectiveness of 810 nm agrees with previous publications, and together with the effectiveness of 660 nm and non‐effectiveness of 730 and 980 nm can be explained by the absorption spectrum of cytochrome oxidase, the candidate mitochondrial chromophore in transcranial LLLT. Lasers Surg. Med. © 2012 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)

Treatment of Mucosal Vascular Malformations With Variable-Pulse Neodymium:Yttrium-Aluminum-Garnet Laser.

Actas Dermo-Sifiliograficas — Fri, 30 Dec 2011 05:00:00 +0100

CONCLUSIONS: Given its efficacy and ease of use, Nd:YAG may become a treatment of choice for mucosal vascular lesions. Comparative studies are now required to assess its potential superiority over other treatment options. PMID: 22209896 [PubMed - as supplied by publisher] (Source: Actas Dermo-Sifiliograficas)

Photorejuvenation using long‐pulsed alexandrite and long‐pulsed neodymium:yttrium–aluminum–garnet lasers: A pilot study of clinical outcome and patients’ satisfaction in Koreans

The Journal of Dermatology — Thu, 29 Dec 2011 05:00:00 +0100

AbstractLong‐pulsed 755‐nm alexandrite and long‐pulsed 1064‐nm neodymium:yttrium–aluminum–garnet (Nd:YAG) lasers have been used for photorejuvenation of the face. The aim of this study was to investigate the safety and efficacy of long‐pulsed alexandrite and long‐pulsed Nd:YAG lasers for photorejuvenation in Korea. One hundred and sixteen Korean patients with photo‐aged facial skin were enrolled. Sixty‐two patients with facial pigmentation underwent long‐pulsed alexandrite laser treatment. Eleven patients that wanted to improve facial pigmentation with minimal pain had quasi‐long‐pulsed alexandrite laser treatment. Forty three patients had long‐pulsed Nd:YAG laser therapy. Outcome assessments included standard photographs and global evaluation by blinded investi...

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In Vitro effect of low-level laser therapy on typical oral microbial biofilms.

Braz Dent J — Sun, 25 Dec 2011 03:42:03 +0100

Authors: Basso FG, Oliveira CF, Fontana A, Kurachi C, Bagnato VS, Spolidório DM, Hebling J, Costa CA Abstract The aim of this study was to evaluate the effect of specific parameters of low-level laser therapy (LLLT) on biofilms formed by Streptococcus mutans, Candida albicans or an association of both species. Single and dual-species biofilms - SSB and DSB - were exposed to laser doses of 5, 10 or 20 J/cm2 from a near infrared InGaAsP diode laser prototype (LASERTable; 780 ± 3 nm, 0.04 W). After irradiation, the analysis of biobilm viability (MTT assay), biofilm growth (cfu/mL) and cell morphology (SEM) showed that LLLT reduced cell viability as well as the growth of biofilms. The response of S. mutans (SSB) to irradiation was similar for all laser doses and the biofilm growth wa...

Effect of low-level laser therapy on proliferation, differentiation, and adhesion of steroid-treated osteoblasts

Lasers in Medical Science — Wed, 21 Dec 2011 20:07:00 +0100

Abstract There has recently been constant effort to evaluate therapies that may have a positive effect on bone regeneration. However, there are few studies in the literature on the effects of low-level laser therapy (LLLT) involving tissues treated with anabolic steroids. The present study evaluated the effects of LLLT (AsGaAl 780 nm, 3 J/cm2, 10 mW, beam spot of 0.04 cm2, total energy 0.12 J) on the proliferation, adhesion, and differentiation of osteoblasts cultured in the presence of nandrolone decanoate (ND). The MTT method was employed to evaluate cell proliferation and adhesion. Cell differentiation was evaluated by measuring alkaline phosphatase activity. There was a significant decrease in cell proliferation in the irradiated group treated w...

Spectroscopic and histological evaluation of wound healing progression following Low Level Laser Therapy (LLLT)

Journal of Biophotonics — Sat, 17 Dec 2011 13:50:52 +0100

AbstractThe present study focuses on the evaluation of the effect of He‐Ne laser on tissue regeneration by monitoring collagen synthesis in wound granulation tissues in Swiss albino mice using analysis of laser induced fluorescence (LIF) and light microscopy techniques. The spectral analyses of the wound granulation tissues have indicated a dose dependent increase in collagen levels during the post‐wounding days. The histological examinations on the other hand have also shown a significant increase in collagen deposition along with the reduced edema, leukocytes, increased granulation tissue, and fibroblast number in the optimal laser dose treated group compared to the non‐illuminated controls. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim) (Source: Journal of Biophotonics...

Efficacy of low level laser therapy associated with exercises in knee osteoarthritis: a randomized double-blind study.

Clinical Rehabilitation — Wed, 14 Dec 2011 05:00:00 +0100

Conclusion: Our findings suggest that low level laser therapy when associated with exercises is effective in yielding pain relief, function and activity on patients with osteoarthritis of the knees. PMID: 22169831 [PubMed - as supplied by publisher] (Source: Clinical Rehabilitation)

Fifty Years of Ophthalmic Laser Therapy [Editorial]

Archives of Opthalmology — Mon, 12 Dec 2011 05:00:00 +0100

(Source: Archives of Opthalmology)

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Effect of Low-Level Laser Therapy in the Treatment of Burning Mouth Syndrome: A Case Series

Photomedicine and Laser Surgery — Wed, 07 Dec 2011 16:09:54 +0100

Photomedicine and Laser Surgery Dec 2011, Vol. 29, No. 12: 793-796. (Source: Photomedicine and Laser Surgery)

Effect of low-level laser therapy on cochlear hair cell recovery after gentamicin-induced ototoxicity

Lasers in Medical Science — Sat, 03 Dec 2011 16:49:59 +0100

Abstract Cochlear hair cells are the sensory receptors of the auditory system. It is well established that antibiotic drugs such as gentamicin can damage hair cells and cause hearing loss. Rescuing hair cells after ototoxic injury is an important issue in hearing recovery. Although many studies have indicated a positive effect of low-level laser therapy (LLLT) on neural cell survival, there has been no study on the effects of LLLT on cochlear hair cells. Therefore, the aim of this study was to elucidate the effects of LLLT on hair cell survival following gentamicin exposure in organotypic cultures of the cochlea of rats. The cochlea cultures were then divided into a control group (n = 8), a laser-only group (n = 8), a gentamicin-only group (n = 8) and a gentamic...

Virginia Tech's Rylander wins national biomedical engineering award

EurekAlert! - Medicine and Health — Thu, 01 Dec 2011 05:00:00 +0100

(Virginia Tech) Marissa Nichole Rylander, an associate professor at Virginia Tech faculty, combines nanotechnology, laser therapy, and dynamic imaging to study tumor progression and to develop novel cancer treatments. (Source: EurekAlert! - Medicine and Health)

Immediate vesicular eruption caused by topical 23% lidocaine 7% tetracaine ointment in a patient scheduled for laser therapy: a new adverse drug reaction

Journal of Cosmetic Dermatology — Thu, 01 Dec 2011 05:00:00 +0100

We report the cases of two patients who presented for ablative laser therapy. Immediately after application of 23% lidocaine and 7% tetracaine mixed in an ointment base, the patients developed a diffuse eruption of vesicles and bullae on a well‐demarcated erythematous base. The patients’ lesions resolved after <1 week with gentle skin care. One patient developed macules of postinflammatory hyperpigmentation which faded over 2 months. One patient chose to cancel his laser therapy because of concerns over reproducing this adverse reaction, while the second will proceed using a different topical anesthetic agent. While topical anesthetic agents should generally be considered safe, they are not without risks. These cases illustrate a previously unreported adverse event. Clinicians s...

The Insertion of Self Expanding Metal Stents With Flexible Bronchoscopy Under Sedation for Malignant Tracheobronchial Stenosis: A Single-Center Retrospective Analysis.

Archivos de Bronconeumologia — Thu, 01 Dec 2011 05:00:00 +0100

CONCLUSION: Ultraflex stents offer a safe and effective therapy for patients who are inoperable or unresectable that otherwise would have no alternative therapy. It has an immediate beneficial effect upon patients, not only through symptom relief but, in some, through prolongation of life. Survival data is no worse than other studies using different varieties of stents and insertion techniques indicating its longer-term efficacy. Moreover, this report highlights the feasibility of performing this procedure successfully in a respiratory unit, without the need for general anesthesia. PMID: 22137422 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)

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Formation of Fibrosis After Nonablative and Ablative Fractional Laser Therapy

Dermatologic Surgery — Mon, 28 Nov 2011 05:00:00 +0100

ConclusionsAssuming that the dermal response is comparable in AD, PIH, and BN, at the given settings, ablative FLT may induce fibrosis, whereas treatment with nonablative FLT does not. Whether formation of fibrosis has to be regarded as dermal remodeling or a subtle subclinical form of scarring should be investigated in future research. (Source: Dermatologic Surgery)

Efficacy of 308‐nm Xenon Chloride Excimer Laser in Pityriasis Alba

Dermatologic Surgery — Mon, 28 Nov 2011 05:00:00 +0100

ConclusionThe 308‐nm excimer laser is an effective therapeutic option for PA. (Source: Dermatologic Surgery)

Acneiform rash due to epidermal growth factor receptor inhibitors: high-level laser therapy as an innovative approach

Lasers in Medical Science — Fri, 25 Nov 2011 17:59:52 +0100

Abstract Acneiform rash associated with epidermal growth factor receptor inhibitors frequently presents facial manifestations. The treatment modality for such lesions still needs to be elucidated. The aim of this original report was to evaluate the effectiveness of high-level laser therapy in reducing the severity of facial acneiform rash induced by cetuximab, an epidermal growth factor receptor inhibitors. Four patients with metastatic colorectal cancer and two patients with head and neck cancer showing cetuximab-induced facial rash were treated by high-level laser therapy in two 8-min-long consecutive sessions/day over a 4-day treatment. Patients wore protective glasses to prevent eye damage related to laser light. Subsequently, patients were seen once a week for up to 2...

How to Report Low-Level Laser Therapy (LLLT)/Photomedicine Dose and Beam Parameters in Clinical and Laboratory Studies

Photomedicine and Laser Surgery — Tue, 22 Nov 2011 17:21:56 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Treatment of residual pockets with photodynamic therapy, diode laser, or deep scaling. A randomized, split-mouth controlled clinical trial

Lasers in Medical Science — Mon, 21 Nov 2011 18:08:57 +0100

Using 5-Aminolevulinic Acid and Pulsed Dye Laser for Photodynamic Treatment of Oral Leukoplakia [Original Article]

Archives of Otolaryngology — Mon, 21 Nov 2011 05:00:00 +0100

Conclusions Photodynamic therapy with 5-aminolevulinic acid and pulsed dye laser could be used to achieve regression of oral leukoplakia. The treatment is safe and well tolerated. An application time of 1.5 hours and laser radiant exposure of 8 J/cm2 with 1.5-ms pulse time were found to be the optimal settings in this study. The high-power laser used in this study allows completion of laser therapy within 1 to 3 minutes. Further studies are necessary to determine the optimal laser radiant exposure and drug application to maximize the response rate. Trial Registration clinicaltrials.gov Identifier: NCT00571974 (Source: Archives of Otolaryngology)

Successful treatment of cutaneous venous malformations in a blue rubber bleb nevus syndrome patient by Nd:YAG laser

British Journal of Dermatology — Sat, 19 Nov 2011 05:00:00 +0100

Conclusion: Nd:YAG laser therapy is effective in the treatment of mucocutaneous lesions in patients suffering from Blue Rubber Bleb Nevus Syndrome. (Source: British Journal of Dermatology)

Successful treatment of cutaneous venous malformations in a blue rubber bleb nevus syndrome patient by Nd:YAG laser.

The British Journal of Dermatology — Sat, 19 Nov 2011 05:00:00 +0100

Conclusion: Nd:YAG laser therapy is effective in the treatment of mucocutaneous lesions in patients suffering from Blue Rubber Bleb Nevus Syndrome. PMID: 22098394 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Theralase Introduces Low Priced Laser Series

HSMN NewsFeed — Thu, 17 Nov 2011 12:56:39 +0100

New TLC-900 Laser Series Offers Theralase's Renowned Clinical Performance at Lower Prices TORONTO, ONTARIO--(Healthcare Sales & Marketing Network)- Theralase Technologies Inc. (TSX-V: TLT.V ) announced today that it has launched a new version of the hig... DevicesTheralase Technologies, TLC-900 series, Low Level Laser Therapy, laser (Source: HSMN NewsFeed)

Fractional CO2 Laser Improves Postburn Hypertrophic ScarsFractional CO2 Laser Improves Postburn Hypertrophic Scars

Medscape Today Headlines — Wed, 16 Nov 2011 21:22:25 +0100

Fractional CO2 laser therapy is an effective, well-tolerated treatment for postburn hypertrophic scars, and it appears safe for patients with dark skin. Medscape Medical News (Source: Medscape Today Headlines)

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Prevention of recurrent herpes labialis outbreaks through low-intensity laser therapy: a clinical protocol with 3-year follow-up

Lasers in Medical Science — Tue, 15 Nov 2011 16:48:47 +0100

Content Type Journal ArticleCategory Brief ReportPages 1-7DOI 10.1007/s10103-011-1019-6Authors Carlos de Paula Eduardo, Special Laboratory of Lasers in Dentistry – LELO, Department of Restorative Dentistry, Faculdade de Odontologia da Universidade de São Paulo, São Paulo, BrazilLetícia Mello Bezinelli, Hematology and Bone Marrow Transplantation, Hospital Israelita Albert Einstein – HIAE, São Paulo, BrazilFernanda de Paula Eduardo, Hematology and Bone Marrow Transplantation, Hospital Israelita Albert Einstein – HIAE, São Paulo, BrazilRoberta Marques da Graça Lopes, Hematology and Bone Marrow Transplantation, Hospital Israelita Albert Einstein – HIAE, São Paulo, BrazilKaren Müller Ramalho, Special Laboratory of Lasers in Dentistry – LELO, Department of Restorative Denti...

Development of a minimally invasive laser needle system: effects on cortical bone of osteoporotic mice

Lasers in Medical Science — Mon, 14 Nov 2011 16:54:51 +0100

Abstract Many studies have shown the positive effects of low-level laser therapy in the treatment of bone disease. However, laser radiation is scattered in the skin surface which reduces the initial photon density for tissue penetration and consequently the therapeutic efficacy. We developed a minimally invasive laser needle system (MILNS) to avoid laser scattering in tissue and investigated its stimulatory effects in the cortical bone of osteoporotic mice. The MILNS was designed to stimulate cortical bone directly by employing fine hollow needles to guide 100 μm optical fibers. The study animals comprised 12 mice which were subjected to sciatic denervation of the right hind limb and were randomly divided into two groups, a sham group and a laser group which were tre...

The Electrosurgical Knife in an Optimized Intermittent Cutting Mode for the Endoscopic Treatment of Benign Web-Like Tracheobronchial Stenosis.

Archivos de Bronconeumologia — Thu, 10 Nov 2011 05:00:00 +0100

CONCLUSION: The use of this technique is effective for the treatment of benign web-like tracheobronchial stenosis as all the patients showed clinical and functional improvement, and less than 50% required a second intervention. In comparison with laser therapy, an advantage of this technique is that less fibrin is produced, probably due to the reduced anti-coagulation effect. PMID: 22079133 [PubMed - as supplied by publisher] (Source: Archivos de Bronconeumologia)

Agminated, Eruptive Pyogenic Granuloma‐Like Lesions Developing over Congenital Vascular Stains

Pediatric Dermatology — Tue, 08 Nov 2011 05:00:00 +0100

We report three infants who developed agminated pyogenic granulomas over congenital vascular malformations, all of which had an aggressive growth pattern. There were no precipitating events such as laser therapy or surgery. Lesions were excised. (Source: Pediatric Dermatology)

Glomuvenous Malformations (Familial generalized multiple glomangiomas).

Dermatol Online J — Tue, 08 Nov 2011 04:35:03 +0100

Authors: Brauer JA, Anolik R, Tzu J, Meehan S, Lieber CD, Geronemus RG Abstract A 15-year-old boy with a diagnosis of generalized multiple glomangiomas was referred for evaluation and treatment of enlarging and increasingly painful lesions on his right ankle. The patient underwent a series of two treatments with long-pulsed KTP 1064 nm laser that resulted in substantial improvement in appearance and decreased pain. Generalized glomuvenous malformations, or multiple glomangiomas, are the less common presentation of proliferation of glomus cells and may have extracutaneous involvement. Whereas surgical management is often employed and definitive for solitary lesions, interventions such as laser therapy, may be beneficial for improvement of functional impairment and cosmesis as was ob...

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Combination treatment of 10,600 nm ablative carbon dioxide fractional laser and narrow band UVB in refractory non-segmental vitiligo: A prospective, randomized half-body comparative study.

The British Journal of Dermatology — Fri, 04 Nov 2011 04:00:00 +0100

Conclusions: This study suggests that fractional CO2 laser therapy followed by NB-UVB could be used effectively and safely as an alternative modality for the treatment of refractory vitiligo. PMID: 22050270 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Combination treatment of 10,600 nm ablative carbon dioxide fractional laser and narrow band UVB in refractory non‐segmental vitiligo: A prospective, randomized half‐body comparative study

British Journal of Dermatology — Fri, 04 Nov 2011 04:00:00 +0100

Conclusions: This study suggests that fractional CO2 laser therapy followed by NB‐UVB could be used effectively and safely as an alternative modality for the treatment of refractory vitiligo. (Source: British Journal of Dermatology)

Combination treatment by 10 600 nm ablative fractional carbon dioxide laser and narrowband ultraviolet B in refractory nonsegmental vitiligo: a prospective, randomized half‐body comparative study

British Journal of Dermatology — Fri, 04 Nov 2011 04:00:00 +0100

Conclusions This study suggests that fractional CO2 laser therapy followed by NB‐UVB phototherapy could be used effectively and safely as an alternative modality for the treatment of refractory vitiligo. (Source: British Journal of Dermatology)

Effects of low-level laser therapy in combination with physiotherapy in the management of rotator cuff tendinitis

Lasers in Medical Science — Thu, 03 Nov 2011 16:55:09 +0100

The objective of this study was to evaluate the possible additive effects of low-power laser treatment in combination with conventional physiotherapy endeavors in these patients. A total of 50 patients who were referred to the Physical Medicine and Rehabilitation Clinic with shoulder pain and rotator cuff disorders were selected. Pain severity measured with visual analogue scale (VAS), abduction, and external rotation range of motion in shoulder joint was measured by goniometry, and evaluation of daily functional abilities of patients was measured by shoulder disability questionnaire. Twenty-five of the above patients were randomly assigned into the control group and received only routine physiotherapy. The other 25 patients were assigned into the experimental group and received conv...

The Effect of 670-nm Low Laser Therapy on Herpes Simplex Type 1

Photomedicine and Laser Surgery — Wed, 02 Nov 2011 15:27:16 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

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The Nuts and Bolts of Low-level Laser (Light) Therapy.

Annals of Biomedical Engineering — Wed, 02 Nov 2011 04:00:00 +0100

Authors: Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR Abstract Soon after the discovery of lasers in the 1960s it was realized that laser therapy had the potential to improve wound healing and reduce pain, inflammation and swelling. In recent years the field sometimes known as photobiomodulation has broadened to include light-emitting diodes and other light sources, and the range of wavelengths used now includes many in the red and near infrared. The term "low level laser therapy" or LLLT has become widely recognized and implies the existence of the biphasic dose response or the Arndt-Schulz curve. This review will cover the mechanisms of action of LLLT at a cellular and at a tissular level and will summarize the various light sources and principles of dosimetry that...

Neurodevelopmental outcomes after laser therapy for twin-twin transfusion syndrome: a systematic review and meta-analysis.

Obstetrics and Gynecology — Tue, 01 Nov 2011 04:00:00 +0100

CONCLUSION: : A small number (11.1%) of cases of twin-twin transfusion syndrome treated with laser therapy are affected with neurologic impairment that manifests during infancy. A strict follow-up of apparently healthy neonates is warranted. PMID: 22015883 [PubMed - in process] (Source: Obstetrics and Gynecology)

Coronally advanced flap adjunct with low intensity laser therapy: a randomized controlled clinical pilot study.

Journal of Clinical Periodontology — Tue, 01 Nov 2011 04:00:00 +0100

CONCLUSION: Within the limitations of this study, the results indicated that LILT may improve the predictability of CAF in multiple recessions. PMID: 22092477 [PubMed - in process] (Source: Journal of Clinical Periodontology)

Patient responses to Er:YAG laser when used for conservative dentistry

Lasers in Medical Science — Mon, 31 Oct 2011 16:58:22 +0100

This study may be relevant when determining the overall satisfaction of patients with this new technology. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s10103-011-1012-0Authors Carlo Fornaini, TELEO Laboratory, Faculty of Dentistry, University of Nice-Sophia Antipolis (France), 24, Avenue des Diables Bleus, 06357 Nice Cedex, FranceDavid Riceputi, TELEO Laboratory, Faculty of Dentistry, University of Nice-Sophia Antipolis (France), 24, Avenue des Diables Bleus, 06357 Nice Cedex, FranceLaurence Lupi-Pegurier, TELEO Laboratory, Faculty of Dentistry, University of Nice-Sophia Antipolis (France), 24, Avenue des Diables Bleus, 06357 Nice Cedex, FranceJean Paul Rocca, TELEO Laboratory, Faculty of Dentistry, University of Nice-Sophia Antipolis (France), 24, Aven...

Comparison of the long - term effectiveness of physiotherapy programs with low - level laser therapy and pulsed magnetic field in patients with carpal tunnel syndrome.

Advances in Medical Sciences — Sat, 29 Oct 2011 04:00:00 +0100

Conclusions: Although after LLL as well as PMF therapy clinical improvement was observed, the most significant differences were registered after the second series and persisted for up to 6 months in both groups. PMID: 22037175 [PubMed - as supplied by publisher] (Source: Advances in Medical Sciences)

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Iatrogenic laser complications

Clinics in Dermatology — Sat, 22 Oct 2011 04:59:17 +0100

Abstract: Modern aesthetic laser technology treatment options offer minimally invasive, more affordable alternatives to traditional cosmetic surgery, with the promise of reduced downtime for the patient. Laser therapy can significantly improve the appearance of the skin; however, these procedures also carry potential risks. This contribution will provide a brief overview of current treatment modalities and review potential complications. Emphasis will be on placed on achieving best practices for the prevention of undesired outcomes and optimizing clinical management if complications occur. (Source: Clinics in Dermatology)

Low-level laser irradiation, cyclooxygenase-2 (COX-2) expression and necrosis of random skin flaps in rats

Lasers in Medical Science — Thu, 20 Oct 2011 15:52:46 +0100

Abstract Skin flaps are still a matter of concern among surgeons, as failures can occur leading to flap necrosis. However, low-level laser irradiation has been reported as an effective tool to improve the viability of ischemic flaps, yet its mechanisms of action remain unclear. We investigated the effect of low-level laser irradiation on the viability of random skin flaps in rats and determined COX-2 expression in the flap pedicle. The study animals comprised 24 EPM-1 Wistar rats which were randomly allocated into three equal groups. A cranially based dorsal random skin flap measuring 10 × 4 cm was created in all the animals. In one group, laser irradiation was simulated (sham group), and in the other two groups the animals were irradiated at 12 points with 0.29&...

Low-level laser therapy improves repair following complete resection of the sciatic nerve in rats

Lasers in Medical Science — Tue, 18 Oct 2011 15:57:36 +0100

Abstract The aim of this study is to analyze the effects of low-level laser therapy (LLLT) on the regeneration of the sciatic nerve in rats following a complete nerve resection. Male Wistar rats were divided into a control injury group, injury groups irradiated with a 660-nm laser at 10 or 50 J/cm2, and injury groups irradiated with an 808-nm laser at 10 or 50 J/cm2. Treatment began 24 h following nerve resection and continued for 15 days. Using the sciatic functional index (SFI), we show that the injured animals treated with 660 nm at 10 and 50 J/cm2 had better SFI values compared with the control injury and the 808-nm groups. Animals irradiated with the 808-nm laser at 50 J/cm2 show higher values for fiber density than do control animals....

Low-level diode laser therapy reduces lipopolysaccharide (LPS)-induced bone cell inflammation

Lasers in Medical Science — Sat, 15 Oct 2011 15:47:28 +0100

Conclusions: low-level diode laser treatment increased the MG63 cell proliferative ability and decreased the expression of inflammatory mediators in MG63 cells. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s10103-011-1006-yAuthors Tsui Hsien Huang, Graduate School of Dentistry, Chung Shan Medical University Hospital, Chung Shan Medical University, 110, section 1, Chien Kuo N Road, Taichung City, 40201 TaiwanYu Chuan Lu, Graduate School of Dentistry, Chung Shan Medical University Hospital, Chung Shan Medical University, 110, section 1, Chien Kuo N Road, Taichung City, 40201 TaiwanChia Tze Kao, Graduate School of Dentistry, Chung Shan Medical University Hospital, Chung Shan Medical University, 110, section 1, Chien Kuo N Road, Taichung City, 40201 Taiwan ...

Narrow-band red LED light promotes mouse hair growth through paracrine growth factors from dermal papilla

Journal of Dermatological Science — Thu, 13 Oct 2011 04:00:00 +0100

Sevaral clinical reports have suggested that hair growth is promoted by low-level laser therapy (LLLT), defined as therapy using red-beam or near-infrared laser with a wavelength of 600–1100nm and an output power of 1–500mW, since Mester et al. reported effect of LLLT on hair growth in 1967. However, the irradiation area of laser system is small, and most systems are expensive and relatively immobile. On the other hand, light emitting diode (LED) light has many advantages related to safety and superior portability compared to UV and laser therapies, because they are low-coherent, quasi-monochromatic and non-thermal. We developed a new narrow-band LED (Mignon belle LT-1 Crystalline by MIGNON BELLE CO., LTD., Osaka, Japan), and utilized this red LED (638nm with half band width 3nm) to ex...

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PEODDN Treated With a Combination Erbium/CO2 LaserPEODDN Treated With a Combination Erbium/CO2 Laser

Medscape Today Headlines — Tue, 11 Oct 2011 12:02:20 +0100

Porokeratotic eccrine ostial and dermal duct nevus is an uncommon disease that presents early in childhood. Treatment is often unsuccessful, but for this 12-year-old, laser therapy proved effective. Dermatology Online Journal (Source: Medscape Today Headlines)

Endovenous ablation (radiofrequency and laser) and foam sclerotherapy versus conventional surgery for great saphenous vein varices.

Cochrane Database of Systematic Reviews — Tue, 11 Oct 2011 01:20:04 +0100

CONCLUSIONS: Currently available clinical trial evidence suggests RFA and EVLT are at least as effective as surgery in the treatment of great saphenous varicose veins. There are insufficient data to comment on USGFS. Further randomised trials are needed. We should aim to report and analyse results in a congruent manner to facilitate future meta-analysis. PMID: 21975750 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)

In vivo vitiligo induction and therapy model : double blind, randomized clinical trial

Pigment Cell Research — Mon, 10 Oct 2011 04:00:00 +0100

In this study, we developed an in vivo vitiligo induction model to explore the underlying mechanisms leading to Koebner’s phenomenon and to evaluate the efficacy of therapeutic strategies. The model consisted of 12 pigmented test regions on the back of generalized vitiligo patients that were exposed to 3 Koebner induction methods: cryotherapy, 755nm laser therapy and epidermal abrasion. In addition, 4 cream treatments (pimecrolimus, tacrolimus, steroid and placebo) were randomly applied. Koebnerization was efficiently induced by all 3 induction methods. In general, cryotherapy was the best method of koebner induction, followed by 755nm laser therapy and epidermal abrasion. Reproducible results were obtained which showed enhanced depigmented surface areas and higher amounts of T lymphocyt...

In vivo vitiligo induction and therapy model: double‐blind, randomized clinical trial

Pigment Cell Research — Mon, 10 Oct 2011 04:00:00 +0100

In this study, we developed an in vivo vitiligo induction model to explore the underlying mechanisms leading to Koebner’s phenomenon and to evaluate the efficacy of therapeutic strategies. The model consisted of 12 pigmented test regions on the back of generalized vitiligo patients that were exposed to three Koebner induction methods: cryotherapy, 755 nm laser therapy, and epidermal abrasion. In addition, four cream treatments (pimecrolimus, tacrolimus, steroid and placebo) were randomly applied. Koebnerization was efficiently induced by all three induction methods. In general, cryotherapy was the best method of Koebner induction, followed by 755 nm laser therapy and epidermal abrasion. Reproducible results were obtained, which showed enhanced depigmented surface areas and higher amo...

In vivo vitiligo induction and therapy model: double-blind, randomized clinical trial.

Pigment Cell and Melanoma Research — Mon, 10 Oct 2011 04:00:00 +0100

In this study, we developed an in vivo vitiligo induction model to explore the underlying mechanisms leading to Koebner's phenomenon and to evaluate the efficacy of therapeutic strategies. The model consisted of 12 pigmented test regions on the back of generalized vitiligo patients that were exposed to three Koebner induction methods: cryotherapy, 755 nm laser therapy, and epidermal abrasion. In addition, four cream treatments (pimecrolimus, tacrolimus, steroid and placebo) were randomly applied. Koebnerization was efficiently induced by all three induction methods. In general, cryotherapy was the best method of Koebner induction, followed by 755 nm laser therapy and epidermal abrasion. Reproducible results were obtained, which showed enhanced depigmented surface areas and higher amoun...

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Endovenous laser therapy: Evolution of practice

International Journal of Surgery — Thu, 06 Oct 2011 22:52:32 +0100

Aim: Endovenous Laser Therapy (EVLT) is a popular treatment for varicose veins typically carried out in an office setting. We aimed to assess the evolution of EVLT practice in a tertiary care vascular surgical unit. (Source: International Journal of Surgery)

Endo-venous laser therapy (EVLT) for treatment of symptomatic varicose veins: A retrospective audit of 970 cases experience at university hospital Lewisham

International Journal of Surgery — Thu, 06 Oct 2011 22:52:31 +0100

Objectives: EVLT is an established effective treatment of varicose veins. Its aim is to accomplish haemodynamic elimination of incompetent truncal veins through endothermal damage of the vein wall causing occlusion. We analysed all cases of EVLT at University Hospital Lewisham since 2007. (Source: International Journal of Surgery)

Blood Loss Comparison During Transurethral Resection of Prostate and High Power GreenLight™ Laser Therapy Using Isotopic Measure of Red Blood Cells Volume

Journal of Endourology — Wed, 05 Oct 2011 19:10:04 +0100

Journal of Endourology Oct 2011, Vol. 25, No. 10: 1655-1659. (Source: Journal of Endourology)

A randomised clinical trial of the effect of low-level laser therapy for perineal pain and healing after episiotomy: A pilot study.

Midwifery — Wed, 05 Oct 2011 04:00:00 +0100

CONCLUSIONS: this pilot study showed that LLLT did not accelerate episiotomy healing. Although there was a reduction in perineal pain mean scores in the experimental group, we cannot conclude that the laser relieved perineal pain. This study led to the suggestion of a new research proposal involving another irradiation protocol to evaluate LLLT's effect on perineal pain relief. PMID: 21982202 [PubMed - as supplied by publisher] (Source: Midwifery)

A preliminary study of hardness and modulus of elasticity in sheep mandibles submitted to distraction osteogenesis and low-level laser therapy

International Journal of Oral and Maxillofacial Surgery — Sat, 01 Oct 2011 04:00:00 +0100

The objective this study is validate the use of nanoindentation tests in research and to assess the quality of newly formed bone in sheep mandibles submitted to Distraction osteogenesis (DO) and low-level laser therapy (LLLT) based on hardness and modulus of elasticity values. We also aim to determine the best moment for the application of laser therapy. (Source: International Journal of Oral and Maxillofacial Surgery)

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Osteonecrosis of the maxilla induced by use of bisphosphonate: a case report

International Journal of Oral and Maxillofacial Surgery — Sat, 01 Oct 2011 04:00:00 +0100

This report describes the clinical case of an oncologic patient treated with zoledronic acid who developed maxillary osteonecrosis after an extraction. The surgical treatment consisted of partial maxillectomy associated with low-level laser therapy. The patient recovered uneventfully and has been receiving dental treatment for oral rehabilitation. Although recurrence of this type of necrotic lesion is frequent, this patient is currently free of any recurrence. (Source: International Journal of Oral and Maxillofacial Surgery)

Functional Improvement After Ablative Fractional Laser Treatment of a Scar Contracture

PM and R — Sat, 01 Oct 2011 04:00:00 +0100

Since first reported in 2004 [], fractional laser therapy has been used for a range of skin indications, including photoaging, dyschromia, melasma, actinic keratoses, and acne scarring []. This technique involves the generation of noncontiguous columnar microscopic thermal wounds that penetrate the skin at depths up to approximately 2 mm with a single pulse. The adjacent untreated skin provides a reservoir of viable tissue, which permits rapid re-epithelialization and dermal remodeling while minimizing potential complications such as infection or worsening scarring [] (). Most laser scar therapy to date has focused on cosmesis. Only a few reports in the literature describe functional improvements in traumatic scars and scar contractures after fractional laser treatment, often as incidental...

Cytomorphometric and clinical investigation of the gingiva before and after low-level laser therapy of gingivitis in children

Lasers in Medical Science — Thu, 29 Sep 2011 06:16:07 +0100

Abstract Gingival epithelial cells are the first physical barrier against periodontal pathogenic microorganisms. Bacterial products may penetrate the epithelium and directly disturb its integrity. We investigated the clinical and cytomorphological status of the gingiva in children with gingivitis before and after low-level laser therapy. The study enrolled 130 children divided into three groups: group 1 comprised 50 children with chronic catarrhal gingivitis who received basic treatment, group 2 comprised 50 children with chronic catarrhal gingivitis who received low-level laser treatment in addition to basic treatment, and group 3 comprised 30 children with healthy gingiva as controls. Oral hygiene and the status of the gingiva were assessed using the appropriate indexes ...

Lasers don't beat surgery for varicose veins

Modern Medicine — Thu, 29 Sep 2011 04:00:00 +0100

New research suggests that laser therapy may be no more effective than the standard saphenous vein-stripping surgery in treating severe varicose veins, Reuters Health reports. (Source: Modern Medicine)

Antiinflammatory effect of low-level laser therapy on Staphylococcus epidermidis endophthalmitis in rabbits

Lasers in Medical Science — Tue, 27 Sep 2011 06:18:10 +0100

Abstract A rabbit model of endophthalmitis was established to evaluate the antiinflammatory effect of low-level laser therapy (LLLT) as an adjunct to treatment for Staphylococcus epidermidis endophthalmitis. Rabbits were randomly divided into three groups to receive intravitreal injections into their left eye: group A received 0.5 mg vancomycin (100 μl), group B received 0.5 mg vancomycin + 0.2 mg dexamethasone (100 μl), and group C received 0.5 mg vancomycin (100 μl) and continuous wave semiconductor laser irradiation (10 mW, λ = 632 nm) focused on the pupil. Slit lamp examination and B-mode ultrasonography were conducted to evaluate the symptoms of endophthalmitis. Polymorphonuclear cells and tumour necrosis factor alph...

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White Gel Pen Easily Marks a Port‐Wine Stain Margin During Pulsed Dye Laser Therapy

Dermatologic Surgery — Tue, 27 Sep 2011 04:00:00 +0100

(Source: Dermatologic Surgery)

Foam injections for varicose veins better for patients and cheaper, study finds

Imperial College News — Mon, 26 Sep 2011 04:00:00 +0100

Foam injections to treat varicose veins cause less pain for patients and could save NHS money compared with laser therapy - News release (Source: Imperial College News)

Mediators involved in retinopathy of prematurity and emerging therapeutic targets

Early Human Development — Fri, 23 Sep 2011 11:36:22 +0100

This article reviews new information available on the molecular pathogenesis of ROP which may result in novel treatments for ROP; it does not discuss the well-known role of oxygen in the development of ROP. (Source: Early Human Development)

Laser for varicose veins no better than surgery

Modern Medicine — Tue, 20 Sep 2011 04:00:00 +0100

NEW YORK (Reuters Health) - Laser therapy of varicose veins doesn't appear to be better than standard surgery, new research suggests. (Source: Modern Medicine)

Quality appraisal of clinical practice guidelines on the use of physiotherapy in rheumatoid arthritis: a systematic review

Rheumatology — Tue, 20 Sep 2011 04:00:00 +0100

Conclusion. Six of eight clinical practice guidelines addressing physiotherapy interventions were recommended or strongly recommended according to the AGREE instrument. In general, guideline recommendations on physiotherapy intervention, from both the recommended guidelines as well as from the not recommended guidelines, lacked detail concerning mode of delivery, intensity, frequency and duration. (Source: Rheumatology)

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Panretinal Photocoagulation for Proliferative Diabetic Retinopathy: Pattern Scan Laser Versus Argon Laser

American Journal of Ophthalmology — Tue, 20 Sep 2011 04:00:00 +0100

Conclusions: When using traditional laser settings, PRP performed with the PASCAL is less effective than that performed with traditional argon laser in effecting lasting regression of retinal neovascularization in the setting of previously untreated high-risk PDR. Physicians may need to change treatment parameters when using PASCAL pattern laser therapy for high-risk PDR. (Source: American Journal of Ophthalmology)

Laser Therapy Matches Standard Varicose Vein Tx (CME/CE)

MedPage Today Dermatology — Mon, 19 Sep 2011 20:17:25 +0100

(MedPage Today) -- Newer laser ablation treatment for varicose veins is just as effective as conventional therapy, researchers found. (Source: MedPage Today Dermatology)

Evaluation of low-level laser therapy in the prevention and treatment of radiation-induced mucositis: A double-blind randomized study in head and neck cancer patients

Oral Oncology — Mon, 12 Sep 2011 04:00:00 +0100

Summary: The purpose of this prospective study was to determine the effect of the low-level laser in the prevention and treatment of mucositis in head and neck cancer patients.A total of 70 patients with malignant neoplasms in the oral cavity or oropharynx were evaluated. The patients were randomized into two low-level laser therapy groups: Group 1 (660nm/15mW/3.8J/cm2/spot size 4mm2) or Group 2 (660nm/5mW/1.3J/cm2/spot size 4mm2) starting on the first day of radiotherapy. Oral mucositis was assessed daily and weekly using the NCI and WHO scales. Oral pain was scored daily with a visual analogue scale before laser application.The patients in Group 1 had a mean time of 13.5days (range 6–26days) to present mucositis grade II, while the patients in Group 2 had a mean time of 9.8days (range ...

Retinoblastoma in Central America: Report from the Central American Association of Pediatric Hematology Oncology (AHOPCA)

Pediatric Blood and Cancer — Fri, 09 Sep 2011 04:00:00 +0100

ConclusionsProtocol‐directed therapy for retinoblastoma in Central America is possible. Patients present with advanced disease and outcome is significantly worse than in middle and high‐income countries. Refusal and abandonment of therapy are societal events that affect outcome. Initiatives aimed at improving early diagnosis, while dedicated treatment centers are developed, are critical. Pediatr Blood Cancer © 2011 Wiley‐Liss, Inc. (Source: Pediatric Blood and Cancer)

Treatment guidelines of lymphatic malformations of the head and neck

Oral Oncology — Fri, 09 Sep 2011 04:00:00 +0100

Summary: Lymphatic malformations, traditionally called lymphangiomas, are diseases caused by development errors of the lymphatic system. About 90% of the cases occur within 2years of age, except a few cases which occur in adulthood, and approximately 75% of the lesions are located in the head and neck region. The lesions can grow rapidly with infection, trauma or bleeding, resulting in disfigurement as well as severe impairment of respiration, swallow and speech. Although lymphatic malformations are benign lesions, they rarely resolve spontaneously, their infiltrating nature coupled with the difficulty in distinguishing involved vital structures of head and neck from adjacent normal tissues makes complete surgical resection even more difficult. The likelihood of postsurgical recurrence and...

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Dose response effects of 810 nm laser light on mouse primary cortical neurons

Lasers in Surgery and Medicine — Thu, 01 Sep 2011 04:00:00 +0100

ConclusionsThe results suggest that LLLT at lower fluences is capable of inducing mediators of cell signaling processes which in turn may be responsible for the beneficial stimulatory effects of the low level laser. At higher fluences beneficial mediators are reduced and high levels of Janus‐type mediators such as ROS and NO (beneficial at low concentrations and harmful at high concentrations) may be responsible for the damaging effects of high‐fluence light and the overall biphasic dose response. Lasers Surg. Med. © 2011 Wiley‐Liss, Inc. (Source: Lasers in Surgery and Medicine)

T287 low level laser therapy in geriatric patients with low back pain

European Journal of Pain Supplements — Thu, 01 Sep 2011 04:00:00 +0100

(Source: European Journal of Pain Supplements)

F278 reduction of pain in lymphangioma by applying low level laser therapy (lllt). a case report

European Journal of Pain Supplements — Thu, 01 Sep 2011 04:00:00 +0100

(Source: European Journal of Pain Supplements)

Analgesic effect of high intensity laser therapy in knee osteoarthritis.

Collegium Antropologicum — Thu, 01 Sep 2011 04:00:00 +0100

Authors: Stiglić-Rogoznica N, Stamenković D, Frlan-Vrgoc L, Avancini-Dobrović V, Vrbanić TS Abstract Knee osteoarthritis (KOA), the most common type of osteoarthritis (OA), is associated with pain and inflammation of the joint capsule, impaired muscular stabilization, reduced range of motion and functional disability. High-intensity laser therapy (HILT) involves higher-intensity laser radiation and causes minor and slow light absorption by chromophores. Light stimulation of the deep structures, due to high intensity laser therapy, activates cell metabolism through photochemical effect. The transmissions of pain stimulus are slowed down and result in a quick achievement of pain relief. The aim of our research was to investigate the prompt analgesic effect of HILT on patients wit...

[Complex Umbilical Cord Vein Pulsations in Cases with Twin-Twin Transfusion Syndrome: Prognostic Implications.]

Ultraschall in der Medizin — Sun, 28 Aug 2011 23:00:00 +0100

CONCLUSION: CP patterns are more frequently found in the recipient twin and are associated with a considerably high mortality rate. Studying the umbilical vein flow pattern in TTTS may provide additional information for counseling and prognosis similar to that obtained by expensive fetal echocardiography. PMID: 21877316 [PubMed - as supplied by publisher] (Source: Ultraschall in der Medizin)

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Effects of low-level laser therapy (808 nm) on isokinetic muscle performance of young women submitted to endurance training: a randomized controlled clinical trial

Lasers in Medical Science — Thu, 25 Aug 2011 15:48:16 +0100

This study tested whether endurance training associated with LLLT could increase human muscle performance in isokinetic dynamometry when compared to the same training without LLLT. The primary objective was to determine the fatigue index of the knee extensor muscles (FIext) and the secondary objective was to determine the total work of the knee extensor muscles (TWext). Included in the study were 45 clinically healthy women (21 ± 1.78 years old) who were randomly distributed into three groups: CG (control group), TG (training group) and TLG (training with LLLT group). The training for the TG and TLG groups involved cycle ergometer exercise with load applied to the ventilatory threshold (VT) for 9 consecutive weeks. Immediately after each training session, LLLT was applied t...

WITHDRAWN: Interventions for treating acute and chronic Achilles tendinitis.

Cochrane Database of Systematic Reviews — Sat, 20 Aug 2011 17:00:05 +0100

CONCLUSIONS: There is insufficient evidence from randomised controlled trials to determine which method of treatment is the most appropriate for the treatment of acute or chronic Achilles tendinitis. Further research is warranted. PMID: 21833940 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)

Diabetic distal symmetric polyneuropathy: Effect of low-intensity laser therapy

Lasers in Medical Science — Fri, 19 Aug 2011 06:40:59 +0100

This study clearly demonstrated a significant positive effect of LILT on improvement of nerve conduction velocity on diabetic distal symmetric polyneuropathy (DSP). This finding supports the therapeutic potential of LILT in DSP. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s10103-011-0977-zAuthors Mohammad Ebrahim Khamseh, Endocrine Research Center (Firouzgar), Institute of Endocrinology and Metabolism (Hemmat Campus), Tehran University of Medical Sciences, Tehran, IranNooshafarin Kazemikho, Endocrine Research Center (Firouzgar), Institute of Endocrinology and Metabolism (Hemmat Campus), Tehran University of Medical Sciences, Tehran, IranRokhsareh Aghili, Endocrine Research Center (Firouzgar), Institute of Endocrinology and Metabolism (Hemmat Campus), T...

Anti‐VEGF for the treatment of diabetic macular edema

Acta Ophthalmologica — Sat, 13 Aug 2011 09:18:59 +0100

Conclusion New therapeutic approaches based on intravitreal injections of anti‐VEGF molecules offer new hope for the management of diabetic macular edema. However, randomized studies are needed in order to attest longterm safety and efficacy profiles. (Source: Acta Ophthalmologica)

Effect of low-level laser therapy after rapid maxillary expansion on proliferation and differentiation of osteoblastic cells

Lasers in Medical Science — Sat, 13 Aug 2011 06:05:24 +0100

Abstract The aim of this study was to investigate the osteoblastic activity of cells derived from the midpalatal suture upon treatment with low-level laser therapy (LLLT) after rapid maxillary expansion (RME). A total of 30 rats were divided into two groups: experimental I (15 rats with RME without LLLT) and experimental II (15 rats with RME + LLLT). The rats were euthanized at 24 h, 48 h, and 7 days after RME, when the osteoblastic cells derived from the rats’ midpalatal suture were explanted. These cells were cultured for periods up to 17 days, and then in vitro osteogenesis parameters and gene expression markers were evaluated. The cellular doubling time in the proliferative stage (3–7 days) was decreased in cultured cells harvested from the...

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Noninterruption of Warfarin Therapy is Safe and Does not Compromise Outcome in Patients Undergoing Endovenous Laser Therapy (EVLT)

Vascular and Endovascular Surgery — Thu, 11 Aug 2011 23:00:00 +0100

Conclusion: Endovenous laser therapy can be safely performed and does not compromise target vessel ablation in patients receiving oral anticoagulation warfarin therapy. Warfarin therapy should not be routinely interrupted in patients undergoing this procedure. (Source: Vascular and Endovascular Surgery)

Comparison of the effects of low-level laser therapy and low-intensity pulsed ultrasound on the process of bone repair in the rat tibia

Revista Brasileira de Fisioterapia — Thu, 11 Aug 2011 17:13:34 +0100

CONCLUSION: Both devices used in this study were able to accelerate the bone healing process in rats. (Source: Revista Brasileira de Fisioterapia)

Blood Loss Comparison During Trans-Urethral Resection of Prostate and High Power GreenLight™ Laser Therapy Using Isotopic Measure of Red Blood Cells Volume

Journal of Endourology — Thu, 11 Aug 2011 15:23:13 +0100

Journal of Endourology , Vol. 0, No. 0. (Source: Journal of Endourology)

Functional and morphometric differences between the early and delayed use of phototherapy in crushed median nerves of rats

Lasers in Medical Science — Thu, 11 Aug 2011 06:57:08 +0100

This study evaluated the functional and quantitative differences between the early and delayed use of phototherapy in crushed median nerves. After a crush injury, low-level laser therapy (GaAs) was applied transcutaneously at the injury site, 3 min daily, with a frequency of five treatments per week for 2 weeks. In the early group, the first laser treatment started immediately after surgery, and in the delayed group, after 7 days. The grasping test was used for functional evaluation of the median nerve, before, 10, and 21 days after surgery, when the rats were killed. Three segments of the median nerve were analyzed histomorphometrically by light microscopy and computer analysis. The following features were observed: myelinated fiber and axon diameters, myelin she...

Dowling-Degos Disease involving the vulva and back: Case report and review of the literature.

Dermatol Online J — Wed, 10 Aug 2011 18:30:03 +0100

We report a patient with the sporadic form of the disease who developed pigmented macules in the rarely involved sites of the lower back and vulva. Her vulvar lesions were treated with Er:YAG laser ablation. PMID: 21810386 [PubMed - in process] (Source: Dermatol Online J)

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Bisphosphonate-related osteonecrosis: laser-assisted surgical treatment or conventional surgery?

Lasers in Medical Science — Tue, 02 Aug 2011 06:18:44 +0100

Abstract Bisphosphonates (BSPs) are used for the treatment of multiple myeloma, metastatic breast and lung cancer, Paget's disease, osteoporosis, hypercalcemia due to malignancy, and many other skeletal diseases. BSPs reduce osteoclastic functions, which result in bone resorption. Bisphosphonates-related osteonecrosis of jaws (BRONJ) is a newly developed term that is used to describe the significant complication in patients receiving bisphosphonates. BSPs are known to exhibit an anti-angiogenetic effect that initiates tissue necrosis of the hard tissue. There is currently no consensus on the correct approach to this issue. The aim of this retrospective study is to compare the effects of laser surgery with biostimulation to conventional surgery in the treatment of BSP-induc...

Letter to Editor

European Journal of Vascular and Endovascular Surgery — Tue, 02 Aug 2011 04:00:00 +0100

In their paper titled “Five-year Results of a Randomised Clinical Trial of Endovenous Laser Ablation of the Great Saphenous Vein with and without Ligation of the Saphenofemoral Junction”, Disselhoff et al. investigated whether additional crossectomy is advantageous in laser treatment of varicosity. The authors’ conclusion that crossectomy does not improve the long-term outcome is incomprehensible. Sclerotherapy was performed in 18 patients due to insufficient lateral branches of the saphenofemoral junction. Sclerotherapy was most likely performed in those patients who had not responded to laser therapy without crossectomy; this therefore signified a disadvantage for the surgical study arm. (Source: European Journal of Vascular and Endovascular Surgery)

Histomorphological and Angiogenic Analyzes of Skin Epithelium After Low Laser Irradiation in Hairless Mice

Sun, 31 Jul 2011 23:00:00 +0100

This study analyzes skin of the masseteric region of mice from the HRS/J strain after three different application regimens (three, six or ten applications per regimen) of low intensity laser at 20 J/cm2 and 40 mW for 20 sec on alternate days. Three experimental groups according to the number of laser applications (three, six or ten) and three control groups (N = 5 animals for each group) were used. On the third day after the last irradiation, all animals were sacrificed and the skin was removed and processed to analyze the relative occupation of the test area by each epithelial layer and the aspects of neovascularization. Data were submitted to statistical analyzes. The irradiated groups compared to their respective controls at each period of time, showed no significant difference in relat...

Histomorphological and Angiogenic Analyzes of Skin Epithelium After Low Laser Irradiation in Hairless Mice.

Anatomical Record — Sun, 31 Jul 2011 23:00:00 +0100

This study analyzes skin of the masseteric region of mice from the HRS/J strain after three different application regimens (three, six or ten applications per regimen) of low intensity laser at 20 J/cm(2) and 40 mW for 20 sec on alternate days. Three experimental groups according to the number of laser applications (three, six or ten) and three control groups (N = 5 animals for each group) were used. On the third day after the last irradiation, all animals were sacrificed and the skin was removed and processed to analyze the relative occupation of the test area by each epithelial layer and the aspects of neovascularization. Data were submitted to statistical analyzes. The irradiated groups compared to their respective controls at each period of time, showed no significant difference in rel...

A retrospective analysis of low dose, intranasal injected bevacizumab (Avastin) in hereditary haemorrhagic telangiectasia

European Archives of Oto-Rhino-Laryngology — Sat, 30 Jul 2011 15:53:09 +0100

Abstract The constantly recurring epistaxis means a great reduction of quality of life for patients with hereditary haemorrhagic telangiectasia (HHT). As yet, an ideal treatment has not been found. Vascular endothelial growth factor (VEGF) has been described as a possible new therapy. In particular, the success of submucosal doses <100 mg has not been analysed before. We injected bevacizumab (Avastin) submucosally in addition to Nd:YAG laser therapy. Doses <7.5 mg were used. To investigate the effect of these additional injections in comparison to laser therapy alone, a retrospective analysis was done. For this purpose a standardized patient questionnaire was completed, which included recording the patients’ Epistaxis Severity Score (ESS) before and after ...

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Scleroderma and Raynaud's Phenomenon Improve with High‐Peak Power Laser Therapy: A Case Report

Dermatologic Surgery — Sun, 24 Jul 2011 23:00:00 +0100

The authors have indicated no significant interest with commercial supporters. (Source: Dermatologic Surgery)

Red (660 nm) and infrared (830 nm) low-level laser therapy in skeletal muscle fatigue in humans: what is better?

Lasers in Medical Science — Thu, 21 Jul 2011 18:12:59 +0100

Abstract In animal and clinical trials low-level laser therapy (LLLT) using red, infrared and mixed wavelengths has been shown to delay the development of skeletal muscle fatigue. However, the parameters employed in these studies do not allow a conclusion as to which wavelength range is better in delaying the development of skeletal muscle fatigue. With this perspective in mind, we compared the effects of red and infrared LLLT on skeletal muscle fatigue. A randomized double-blind placebo-controlled crossover trial was performed in ten healthy male volunteers. They were treated with active red LLLT, active infrared LLLT (660 or 830 nm, 50 mW, 17.85 W/cm2, 100 s irradiation per point, 5 J, 1,785 J/cm2 at each point irradiated, total 20 J irr...

Phototherapy with low-level laser affects the remodeling of types I and III collagen in skeletal muscle repair

Lasers in Medical Science — Thu, 14 Jul 2011 16:50:04 +0100

Abstract The purpose of this article was to analyze the photobiomodulator role of low-level laser therapy (LLLT) on the skeletal muscle remodeling following cryoinjury in rats, focusing the types I and III collagen proteins. Laser phototherapy has been employed to stimulate repair in different tissues. However, its role in skeletal muscle remodeling is not yet well clarified, especially its effect on the collagen component of the extracellular matrix. Fifty adult Wistar rats were divided into four groups: control, sham, cryoinjury, and laser-treated cryoinjury. Laser irradiation was performed three times a week on the injured region using the InGaAlP (indium-gallium-aluminum-phosphorous) laser (660 nm; beam spot of 0.04 cm2, output power of 20 mW, power densi...

Novian Health Receives FDA Approval To Study Breast Cancer Therapy

Medical Design Online News — Thu, 14 Jul 2011 12:15:00 +0100

Novian Health, developer of Novilase Breast Therapy, announced that the US Food and Drug Administration (FDA) has granted investigational device exemption (IDE) approval for the company to start a multi-center study of its Novilase Interstitial Laser Therapy (ILT) System (Source: Medical Design Online News)

Influence of low-level laser therapy on wound healing in nicotine-treated animals

Lasers in Medical Science — Wed, 13 Jul 2011 06:18:24 +0100

In this study we investigated the healing of open wounds created on the back of rats treated with nicotine with or without LLLT. Of 115 animals, 59 received subcutaneous injections of saline solution, and the others received subcutaneous injections of nicotine (3 mg/kg body weight), twice a day throughout the study period. After 30 days, skin wounds were created on the back of the animals. The animals receiving saline injections were divided into two groups: group 1 (G1, n = 29), in which the wounds were left untreated, and group 2 (G2, n = 30), in which the wounds were treated with LLLT (GaAlAs, 660 nm, 30 mW, 5.57 J/cm2 per point, 0.39 J, 13 s per point, 0.42 W/cm2). The animals receiving nicotine injections were also divided into two groups...

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Effects of Low-Level Laser Therapy on the Oxidative Metabolism and Matrix Proteins in the Rat Masseter Muscle

Photomedicine and Laser Surgery — Tue, 12 Jul 2011 03:09:17 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress

Lasers in Medical Science — Fri, 08 Jul 2011 06:32:36 +0100

Abstract The aim of this work was to evaluate the effects of low-level laser therapy (LLLT) on exercise performance, oxidative stress, and muscle status in humans. A randomized double-blind placebo-controlled crossover trial was performed with 22 untrained male volunteers. LLLT (810 nm, 200 mW, 30 J in each site, 30 s of irradiation in each site) using a multi-diode cluster (with five spots - 6 J from each spot) at 12 sites of each lower limb (six in quadriceps, four in hamstrings, and two in gastrocnemius) was performed 5 min before a standardized progressive-intensity running protocol on a motor-drive treadmill until exhaustion. We analyzed exercise performance (VO2 max, time to exhaustion, aerobic threshold and anaerobic threshold), levels of oxidativ...

Stability of dental implants after irradiation with an 830-nm low-level laser: a double-blind randomized clinical study

Lasers in Medical Science — Wed, 06 Jul 2011 05:56:01 +0100

Abstract Little is known about the benefits of low-level laser therapy (LLLT) on improvement of stability of dental implants. The aim of this randomized clinical study was to assess the LLLT effect on implants stability by means of resonance frequency analysis (RFA). Thirty implants were distributed bilaterally in the posterior mandible of eight patients. At the experimental side, the implants were submitted to LLLT (830 nm, 86 mW, 92.1 J/cm2, 0.25 J, 3 s/point, at 20 points), and on the control side, the irradiation was simulated (placebo). The first irradiation was performed in the immediate postoperative period, and it was repeated every 48 h in the first 14 days. The initial implant stability quotient (ISQ) of the implants was measured...

Effect of 980-nm GaAlAs diode laser irradiation on healing of extraction sockets in streptozotocin-induced diabetic rats: a pilot study

Lasers in Medical Science — Wed, 06 Jul 2011 05:55:59 +0100

In this study, we examined the effect of LLLT (low-level laser therapy) on the healing of extraction sockets in diabetic and healthy rats. Forty-eight Sprague-Dawley rats were divided into normal (n = 24) and diabetic (n = 24) rats, and streptozotocin (STZ) injection was used to induce diabetes in the latter. The left and right maxillary first molars of all the rats were extracted. In the non-diabetic rats, the left extraction sockets were not irradiated (group 1) and the right ones were irradiated daily for 3, 5, 7, and 14 days after extraction with a galium-aluminum-arsenide (GaAlAs) diode laser (group 2), and in the diabetic rats, similarly the left ones were not irradiated (group 3) and the right ones were irradiated (group 4). Specimens acquired at these intervals we...

In Vitro Evaluation of Chloroaluminum Phthalocyanine Nanoemulsion and Low-Level Laser Therapy on Human Skin Dermal Equivalents and Bone Marrow MesenchymalStem Cells.

Current Medicinal Chemistry — Sun, 03 Jul 2011 23:00:00 +0100

This article describes the preparation of a nanocarrier for the controlled release of a photosensitizer compound associated with low-level light therapy for skin wound healing treatment and applicable to other skin diseases. A biological model was used as an in vitro skin equivalent based on a three-dimensional culture of fibroblasts and mesenchymal stem cells and denominated by dermal equivalent (DE). Results show that it is possible to use the photomodulation process to control the wound healing in a scratching process and to induce the biomolecules release, both of which are related with the inflammatory wound healing process. In the studies, the MMP-2 and MMP-9 expression from zymography analyses were evaluated. All results showed a dependence on enzymatic activity relating to lowlevel...

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Physiotherapy in hip and knee osteoarthritis: development of a practice guideline concerning initial assessment, treatment and evaluation.

Acta Reumatologica Portuguesa — Fri, 01 Jul 2011 04:00:00 +0100

Conclusions: This update of a Dutch physiotherapy practice guideline on HKOA included 11 recommendations on the initial assessment, treatment and evaluation. The implementation of the guideline in clinical practice needs further evaluation. PMID: 22113602 [PubMed - as supplied by publisher] (Source: Acta Reumatologica Portuguesa)

Expanding the Role of Endovenous Laser Therapy: Results in Large Diameter Saphenous, Small Saphenous, and Anterior Accessory Veins

Annals of Vascular Surgery — Thu, 30 Jun 2011 23:00:00 +0100

Conclusions: Complication rates and closure rates are not significantly different for veins of diameter ≥1 cm and smaller veins. Although more energy is used, this has not translated into higher complication rates, thus making EVLT safe and effective for large vein closure. Significantly higher failure and complication rates were seen in SSV and AAV treatment as compared with GSV treatment. (Source: Annals of Vascular Surgery)

Recent developments in laser therapy for BPH

Trends in Urology, Gynaecology and Sexual Health — Thu, 30 Jun 2011 23:00:00 +0100

AbstractA new generation of lasers for photoselective vaporisation of the prostate operating at 180 watts of power has been introduced for the treatment of benign prostatic hyperplasia. The product was designed to speed up the lasering process and improve fibre durability, while maintaining the safety profile of previous generations. Roger Kirby reviews the history of laser therapy, and discusses whether the treatment can be considered a viable alternative to transurethral resection of the prostate. Copyright © 2011 Wiley Interface Ltd (Source: Trends in Urology, Gynaecology and Sexual Health)

Noninvasive Body Contouring with Radiofrequency, Ultrasound, Cryolipolysis, and Low-Level Laser Therapy

Clinics in Plastic Surgery — Thu, 30 Jun 2011 23:00:00 +0100

This article discusses current noninvasive body-contouring modalities, including suction massage devices, radiofrequency energy, high-frequency focused ultrasound, cryolipolysis, and low-level light laser therapy devices. It also discusses imminent technologies awaiting approval by the Food and Drug Administration, reviews the basic science and clinical effects behind each of these existing and emerging technologies, addresses patient selection and clinical applications of each modality, and discusses the applicability and economics of providing noninvasive lipolysis services in office. (Source: Clinics in Plastic Surgery)

Laser and intense pulsed light therapy for the treatment of hypertrophic scars: a systematic review

British Journal of Dermatology — Mon, 27 Jun 2011 23:00:00 +0100

AbstractHypertrophic scars are difficult to improve and remain a therapeutic challenge. Several lasers and light sources were evaluated in the past decades and showed to improve hypertrophic scars. However, a systematic review is not available. To assess current evidence of efficacy of all laser and intense pulsed light therapies used in the treatment of hypertrophic scars, we performed a systematic review searching electronic databases MEDLINE, EMBASE and CENTRAL. The quality of the controlled clinical trials was evaluated according to the Cochrane Collaboration’s tool for assessing risk of bias. Thirteen articles involving seven different lasers met the inclusion criteria. Most evidence was found for the pulsed dye laser (PDL) 585 nm (8 studies), followed by the PDL 595 nm (2 studies),...

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Laser and intense pulsed light therapy for the treatment of hypertrophic scars: a systematic review.

The British Journal of Dermatology — Mon, 27 Jun 2011 23:00:00 +0100

Authors: Vrijman C, van Drooge AM, Limpens CE, Bos JD, van der Veen JP, Spuls PI, Wolkerstorfer A Hypertrophic scars are difficult to improve and remain a therapeutic challenge. Several lasers and light sources were evaluated in the past decades and showed to improve hypertrophic scars. However, a systematic review is not available. To assess current evidence of efficacy of all laser and intense pulsed light therapies used in the treatment of hypertrophic scars, we performed a systematic review searching electronic databases MEDLINE, EMBASE and CENTRAL. The quality of the controlled clinical trials was evaluated according to the Cochrane Collaboration's tool for assessing risk of bias. Thirteen articles involving seven different lasers met the inclusion criteria. Most evidence was foun...

Tennis elbow

Clinical Evidence — Mon, 27 Jun 2011 22:11:40 +0100

New option(s) added for: Autologous whole blood injections New option added. Categorised as Unknown effectiveness, as we found no RCT evidence to assess the effects of this intervention. Platelet-rich plasma injections New option added. Categorised as Unknown effectiveness, as we found no RCT evidence to assess the effects of this intervention. Manipulation New option added with two systematic reviews. Categorised as Unknown effectiveness, as there remains insufficient good-quality evidence to assess the effects of manipulation on tennis elbow. Combination physical therapies New option added with 5 systematic reviews. Categorised as Unknown effectiveness, as th...

Efficacy and safety of bronchoscopic laser therapy in patients with tracheal and bronchial obstruction: a retrospective single institution report

The Clinical Respiratory Journal — Sun, 26 Jun 2011 23:00:00 +0100

Conclusion: Bronchoscopic laser therapy is a generally safe and effective method to regain airway patency in cases with tracheal or bronchial obstruction and to treat haemoptysis. We observed clinical improvement in terms of reduced dyspnea or controlled haemoptysis in 93% of our patients.Please cite this paper as: Hermes A, Heigener D, Gatzemeier U, Schatz J and Reck M. Efficacy and safety of bronchoscopic laser therapy in patients with tracheal and bronchial obstruction: a retrospective single institution report. Clin Respir J 2011; DOI:10.1111/j.1752‐699X.2011.00247.x. (Source: The Clinical Respiratory Journal)

Low-intensity infrared laser increases plasma proteins and induces oxidative stress in vitro

Lasers in Medical Science — Thu, 23 Jun 2011 16:33:10 +0100

Abstract Low-intensity laser therapy is based on the excitation of endogenous chromophores in biotissues and free-radical generation could be involved in its biological effects. In this work, the effects of the low-intensity infrared laser on plasma protein content and oxidative stress in blood from Wistar rats were studied. Blood samples from Wistar rats were exposed to low-intensity infrared laser in continuous wave and pulsed-emission modes at different fluencies. Plasma protein content and two oxidative stress markers (thiobarbituric acid-reactive species formation and myeloperoxidase activity) were carried out to assess the effects of laser irradiation on blood samples. Low-intensity infrared laser exposure increases plasma protein content, induces lipid peroxidation,...

Histological and immunohistochemical evaluation of new epithelium after removal of oral leukoplakia with Nd:YAG laser treatment

Lasers in Medical Science — Mon, 20 Jun 2011 14:17:54 +0100

In conclusion, this is the first prospective study to show that clinical healing of leukoplakia treated by laser surgery may be accompanied by altered cell turnover in 20% of the cases. Ki67, as a marker of proliferative status, may be a prognostic indicator in the mucosa replacing the lesion. Content Type Journal ArticlePages 1-6DOI 10.1007/s10103-011-0941-yAuthors Lucio Montebugnoli, Department of Oral Science, University of Bologna, Via S. Vitale 59, 40125 Bologna, ItalyFrancesca Frini, Postgraduate School of Oral and Maxillofacial Surgery, University of Bologna, Bologna, ItalyDavide Bartolomeo Gissi, Department of Oral Science, University of Bologna, Via S. Vitale 59, 40125 Bologna, ItalyAndrea Gabusi, Department of Oral Science, University of Bologna, Via S. Vitale 59, 40125 ...

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Specifically requesting surgical tattoo removal: are deep personal motivations involved?

Journal of the European Academy of Dermatology and Venereology — Sat, 18 Jun 2011 16:31:57 +0100

Conclusions Patients seeking surgical removal were aware of the limits and risks of the technique. They expressed intense personal reasons for wanting radical surgical removal. The possibility of surgical tattoo removal should be accessible to patients if the tattoo is small and discussion reveals strong personal motivation. (Source: Journal of the European Academy of Dermatology and Venereology)

Dual Effect of low‐level laser therapy (LLLT) on the acute lung inflammation induced by intestinal ischemia and reperfusion: Action on anti‐ and pro‐inflammatory cytokines

Lasers in Surgery and Medicine — Thu, 16 Jun 2011 22:19:02 +0100

ConclusionThe results indicate that the LLLT attenuates the i‐I/R‐induced acute lung inflammation which favor the IL‐10 production and reduce TNF generation. Lasers Surg. Med. 43:410–420, 2011. © 2011 Wiley‐Liss, Inc. (Source: Lasers in Surgery and Medicine)

Induction of autologous mesenchymal stem cells in the bone marrow by low‐level laser therapy has profound beneficial effects on the infarcted rat heart

Lasers in Surgery and Medicine — Thu, 16 Jun 2011 22:19:01 +0100

ConclusionThe application of LLLT to autologous BM of rats post‐MI offers a novel approach to induce BM‐derived MSCs, which are consequently recruited from the circulation to the infarcted heart and markedly attenuate the scarring process post‐MI. Lasers Surg. Med. 43:401–409, 2011. © 2011 Wiley‐Liss, Inc. (Source: Lasers in Surgery and Medicine)

Unilateral nevoid telangiectasia syndrome: A case report and review of the literature.

Dermatol Online J — Mon, 13 Jun 2011 05:45:04 +0100

We report on a 43-year-old Caucasian female who presented with bright red macules in a unilateral distribution in the left C5-8 and L3-5 dermatomes. Histopathologic examination showed superficial papillary dermal telangiectasia with minimal chronic inflammation. Immunohistochemical stains for estrogen and progesterone receptors (ER/PR) were negative. A diagnosis of unilateral nevoid telangiectasia syndrome (UNTS) was given. UNTS is an uncommon disorder first described by Alfred Blaschko in 1899. It is comprised of telangiectasias occurring in a predominantly unilateral dermatomal distribution and often affecting the trigeminal, cervical, and upper thoracic dermatomes. It can be either congenital or acquired and has a 2:1 female:male ratio. UNTS has been reported in relation to hyperestroge...

Reply

American Journal of Obstetrics and Gynecology — Mon, 13 Jun 2011 04:00:00 +0100

We thank Dr Bernirschke for his valuable comments regarding our recent article. Although we did consider assessing the complete obliteration of all anastomotic vessels as the outcome to assess the proficiency of laser ablation for twin-twin transfusion syndrome (TTTS), such an outcome would require placental injection studies to be performed after birth. There are major limitations to this method. The demise of 1 or both twin fetuses after laser therapy will affect the placental angioarchitecture so that injection studies would not be possible. Therefore, the placental studies are only possible for dual survivors with an intact placenta at the delivery. We would agree that in an ideal setting, recovery of placentas after delivery would provide more insight in the underlying pathology of TT...

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A systematic review with meta-analysis of the effect of low-level laser therapy (LLLT) in cancer therapy-induced oral mucositis

Supportive Care in Cancer — Fri, 10 Jun 2011 06:31:17 +0100

Conclusions There is consistent evidence from small high-quality studies that red and infrared LLLT can partly prevent development of cancer therapy-induced OM. LLLT also significantly reduced pain, severity and duration of symptoms in patients with cancer therapy-induced OM. Content Type Journal ArticlePages 1-9DOI 10.1007/s00520-011-1202-0Authors Jan Magnus Bjordal, Centre for Evidence-Based Practice, Bergen University College-HiB, Moellendalsvn. 6, 5009 Bergen, NorwayRene-Jean Bensadoun, Service d’Oncologie Radiothérapique, CHU de Poitiers, BP 577, 86021 Poitiers Cedex, FranceJan Tunèr, Grängesberg Dental Clinic, Grängesberg, SwedenLucio Frigo, University of Cruzeiro do Sul, Sao Miguel Paulista, SP, BrazilKjersti Gjerde, Department of Clinical Odontology, U...

Treatment of a large congenital melanocytic nevus with dermabrasion and autologous cell suspension (ReCELL®): A case report

Journal of Plastic, Reconstructive and Aesthetic Surgery — Fri, 10 Jun 2011 04:00:00 +0100

We present an illustrated case of a healthy, term, 4 week-old male neonate with a large CMN on his face. The lesion was dermabraded, and non-cultured epithelial autograft harvested from the right post-auricular area was applied.Dressings were no longer required by the 8th post-operative day, and excellent skin pigmentation and texture was achieved by 5 months post-op. (Source: Journal of Plastic, Reconstructive and Aesthetic Surgery)

Topical sucralfate for pain after oral CO2 laser surgery: a prospective, randomized, controlled trial

American Journal of Otolaryngology — Thu, 09 Jun 2011 04:00:00 +0100

Conclusions: This study demonstrated the efficacy of topical sucralfate application in diminishing postoperative pain after CO2 laser therapy for oral leukoplakia. Topical sucralfate can be considered a feasible adjuvant medication for the control of pain after CO2 laser treatment of oral leukoplakia. (Source: American Journal of Otolaryngology)

Laser therapy for twin‐to‐twin transfusion syndrome (TTTS)

Prenatal Diagnosis — Wed, 08 Jun 2011 23:00:00 +0100

AbstractMonochorionic twins are subjected to specific complications which originate in either imbalance or abnormality of the single placenta serving two twins including twin‐to‐twin transfusion syndrome. The diagnosis is well established in overt clinical forms with the association of polyuric polyhydramnios and oliguric oligohydramnios. The best treatment of cases presenting before 26 weeks of gestion is fetoscopic laser ablation of the intertwin anastomoses on the chorionic plate. Although subjected to subtle variations, the core technique follows robust guidelines which could help understanding and acquiring the required skills and experience to perform this procedure. However appropriate and tailored hands‐on training and appropriate perinatal set‐up are critical not only for ...

Short-term effects of high-intensity laser therapy versus ultrasound therapy in the treatment of low back pain: a randomized controlled trial.

European Journal of Physical and Rehabilitation Medicine — Tue, 07 Jun 2011 23:00:00 +0100

CONCLUSION: Our findings obtained after 15 treatment sessions with the experimental protocol suggested greater effectiveness of HILT than of US therapy in the treatment of LBP, proposing HILT as a promising new therapeutic option into the rehabilitation of LBP. PMID: 21654616 [PubMed - as supplied by publisher] (Source: European Journal of Physical and Rehabilitation Medicine)

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Ablative fractional laser therapy as treatment for Becker nevus: A randomized controlled pilot study

Journal of the American Academy of Dermatology — Mon, 06 Jun 2011 04:00:00 +0100

Conclusion: Ablative FLT was moderately effective in some patients with BN. However, postinflammatory hyperpigmentation and relatively negative patient-reported outcomes still preclude ablative FLT from being a standard therapy. Larger studies with different laser settings will be required to optimize this treatment modality. (Source: Journal of the American Academy of Dermatology)

Sclerotherapy: It Is Back and Better

Clinics in Plastic Surgery — Sun, 05 Jun 2011 23:00:00 +0100

This article is a primer for physicians interested in updating their skills in sclerotherapy. It reviews common sclerosants, sclerotherapy techniques, patient evaluation, complications, and recent advancements in sclerotherapy. (Source: Clinics in Plastic Surgery)

Influence of Superpulsed Laser Therapy on Healing Processes Following Tooth Extraction

Photomedicine and Laser Surgery — Wed, 01 Jun 2011 23:51:53 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

Inhibitory effects of visible 650‐nm and infrared 808‐nm laser irradiation on somatosensory and compound muscle action potentials in rat sciatic nerve: implications for laser‐induced analgesia

Journal of the Peripheral Nervous System — Tue, 31 May 2011 23:00:00 +0100

Low‐level laser therapy (LLLT) has been shown in clinical trials to relieve chronic pain and the World Health Organization has added LLLT to their guidelines for treatment of chronic neck pain. The mechanisms for the pain‐relieving effects of LLLT are however poorly understood. We therefore assessed the effects of laser irradiation (LI) on somatosensory‐evoked potentials (SSEPs) and compound muscle action potentials (CMAPs) in a series of experiments using visible (λ = 650 nm) or infrared (λ = 808 nm) LI applied transcutaneously to points on the hind limbs of rats overlying the course of the sciatic nerve. This approximates the clinical application of LLLT. The 650‐nm LI decreased SSEP amplitudes and increased latency after 20 min. CMAP proximal amplitudes and hip/ankle (H/A) rat...

Primary localized cutaneous nodular amyloidosis successfully treated with cyclophosphamide

Australasian Journal of Dermatology — Sun, 29 May 2011 23:00:00 +0100

We present a case of a middle‐aged woman with PLCNA associated with CREST (calcinosis, Raynaud phenomenon, oesophageal motility disorders, sclerodactyly and telangiectasia) syndrome and Sjögren's syndrome responding to cyclophosphamide with no new amyloid deposits and resolution of skin ulceration after many years of resistance to drug therapy. It is important to monitor these patients for progression into systemic amyloidosis. (Source: Australasian Journal of Dermatology)

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Laser hair removal an attractive option for some male patients

Modern Medicine — Sat, 28 May 2011 20:01:27 +0100

Dermatologists whose practices offer laser therapy for hair removal are finding the procedure is becoming increasingly popular among men. "I would say that there is more awareness about hair removal as an option," says Vera Chotzen, M.D., dermatologist and associate director, Laser and Skin Surgery Center of Northern California, Sacramento, Calif. (Source: Modern Medicine)

Flexible bronchoscopy as a valuable diagnostic and therapeutic tool in pediatric intensive care patients: A report on 5 years of experience

Pediatric Pulmonology — Thu, 26 May 2011 23:00:00 +0100

Efficacy of low-level laser therapy in the management of pain, facial swelling, and postoperative trismus after a lower third molar extraction. A preliminary study

Lasers in Medical Science — Thu, 26 May 2011 16:08:41 +0100

Abstract Pain, swelling, and trismus are the most common complications after surgical removal of impacted lower third molars. The aim of this study was to evaluate the analgesic and anti-inflammatory effects of a low-level laser therapy (Laser Smile™, Biolase®, San Clemente, USA) applied to the wound appeared after the surgical removal of impacted lower third molars. A prospective, randomized, and double-blind study was undertaken in 20 healthy patients with two symmetrically impacted lower third molars. The application of a low-level laser was made randomly on one of the two sides after surgery. The experimental side received 5 J/cm2 of energy density, a wavelength of 810 nm, and an output power of 0.5 W. On the control side, a handpiece was applied intra...

Histomorphometric analysis of inflammatory response and necrosis in re-implanted central incisor of rats treated with low-level laser therapy

Lasers in Medical Science — Thu, 26 May 2011 16:08:40 +0100

Abstract Low-level laser therapy is a tool employed in the management of post-operative inflammation process and in the enhancement of reparative process. The aim of the study was to perform histological evaluation of dental and periodontal ligament of rats central upper-left incisor teeth re-implanted and irradiated with low-level laser (InGaAl, 685 nm, 50 J/cm2) 15, 30, and 60 days after re-implantation. Seventy-two male rats had the central upper left incisor removed and kept for 15 min on dry gauze before replantation. Laser was irradiated over the root surface and empty alveolus prior replantation and over surrounding mucosa after the re-implantation. After histological procedures, all slices were analyzed regarding external resorption area and histologi...

Effect of 1,064-nm Nd:YAG laser therapy on GCF IL-1β and MMP-8 levels in patients with chronic periodontitis

Lasers in Medical Science — Wed, 25 May 2011 16:03:16 +0100

This study was performed according to a random split-mouth-design, controlled clinical trial for sulcular debridement on 40 teeth from 20 patients with generalized moderate chronic periodontitis. The periodontal healing outcomes were compared after periodontal treatment with either SRP + NDL at 1 W (test side) or SRP (control side). Plaque index (PI), gingival index (GI), probing pocket depth (PPD), and clinical attachment level (CAL) were recorded, and samples of gingival crevicular fluid (GCF) were taken at baseline and post-therapy (3 and 9 months after treatment). The GCF samples were analyzed for IL-1β and MMP-8. There was postoperative improvement of all clinical parameters in both groups, but test side GI, PPD, and CAL recovery was higher than that of the control side (p...

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Stimulatory effect of low-level laser therapy on root development of rat molars: a preliminary study

Lasers in Medical Science — Wed, 25 May 2011 16:03:14 +0100

Abstract Several studies suggest a biomodulatory influence of low-level laser irradiation in the inflammatory and reparative processes of dental tissues. The aim of this study was to investigate the stimulatory effect of 808-nm laser irradiation on root development of rat molars and also to evaluate the histological reaction of pulp and periapical tissues. Twenty-four 30-day-old Wistar male rats were randomly assigned to three-time and five-time laser therapy groups. After initial x-ray, using mammography equipment, laser energy was applied at a wavelength of 808 nm (2 J/cm2, 100 mW, 20 s) to the midroot area of the lower molars of one side of mouth at repeated intervals of the 48 h. The animals were killed 1 day after the final treatment, and ...

Xanthelasma Palpebrarum Treatment with a 1,450‐nm‐Diode Laser

Dermatologic Surgery — Tue, 24 May 2011 16:28:20 +0100

CONCLUSION The 1,450‐nm‐diode laser treatment is a new, valuable treatment option for xanthelasma palpebrarum, offering relatively mild side effects. Studies including long term follow up and a comparison with alternative treatment modalities are necessary to further assess the clinical utility of this treatment.The authors have indicated no significant interest with commercial supporters. (Source: Dermatologic Surgery)

Study Demonstrates Immediate And Long-Term Benefits Of Laser Treatment For Enlarged Prostate

Health News from Medical News Today — Sun, 22 May 2011 09:00:00 +0100

New research presented at the Annual Meeting of the American Urology Association (AUA) in Washington, DC demonstrates that holmium laser therapy is a safe and durable treatment option for Benign Prostatic Hyperplasia (BPH) - an enlargement of the prostate that affects most men as they age. The study, conducted by researchers from the McGill University Health Centre (MUHC), is the longest comprehensive assessment of this technology to date, and researchers suggest it may now safely be considered the new, size independent, gold standard for treatment of BPH... (Source: Health News from Medical News Today)

Combined use of low level laser therapy and cyclooxygenase-2 selective inhibition on skin incisional wound reepithelialization in mice: a preclinical study

Anais Brasileiros de Dermatologia — Sat, 21 May 2011 16:16:18 +0100

CONCLUSION: The results show that the use of low level laser therapy and ICOX2 in isolation increases epithelial cells, but only low level laser therapy reduced skin keratinocytes. The combined treatment restores innate epithelialization and decreases keratinization in spite of accelerating wound contraction with improvement in the organization of the wound in the skin of mice. (Source: Anais Brasileiros de Dermatologia)