MedWorm: Light Therapy

On the application of light therapy in German-speaking countries. - Fischer R, Kasper S, Pjrek E, Winkler D.

SafetyLit: All (Unduplicated) — Sat, 14 Jan 2012 23:37:58 +0100

Many studies have investigated seasonal affective disorder (SAD; fall-winter-depression) and its treatment with light therapy (LT). However, to the best of our knowledge, no other study has investigated the usage of LT in Europe since 1994. Thus, we perfor... (Source: SafetyLit: All (Unduplicated))

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Alzheimer's Patients Benefit From Light Therapy

Health News from Medical News Today — Fri, 13 Jan 2012 09:00:00 +0100

Exposure to light appears to have therapeutic effects on Alzheimer's disease patients, a Wayne State University researcher has found. In a study published recently in the Western Journal of Nursing Research, LuAnn Nowak Etcher, Ph.D., assistant professor of nursing, reported that patients treated with blue-green light were perceived by their caregivers as having improved global functioning. Caregivers said patients receiving the treatment seemed more awake and alert, were more verbally competent and showed improved recognition, recollection and motor coordination... (Source: Health News from Medical News Today)

On the application of light therapy in German-speaking countries

European Archives of Psychiatry and Clinical Neuroscience — Fri, 06 Jan 2012 16:47:34 +0100

Abstract Many studies have investigated seasonal affective disorder (SAD; fall-winter-depression) and its treatment with light therapy (LT). However, to the best of our knowledge, no other study has investigated the usage of LT in Europe since 1994. Thus, we performed a survey in hospitals with adult psychiatric departments in German-speaking countries by questionnaire. First, a questionnaire was constructed, considering also recent developments in LT. This questionnaire was sent to all hospitals with adult psychiatric departments listed in the “Deutsches Krankenhaus Adressbuch,” which contains hospitals from all German-speaking countries (Germany, Switzerland, and Austria). Non-responders were asked to answer the questionnaire by mail and by phone. We achieved a compl...

Light therapy: Methodological issues from an engineering perspective.

Technology and Health Care — Sun, 01 Jan 2012 05:00:00 +0100

Authors: van Hoof J, Westerlaken AC, Aarts MP, Wouters EJ, Schoutens AM, Sinoo MM, Aries MB Abstract Light therapy is increasingly administered and studied as a non-pharmacologic treatment for a variety of health-related problems, including treatment of people with dementia. Light therapy comes in a variety of ways, ranging from being exposed to daylight, to being exposed to light emitted by light boxes and ambient bright light. Light therapy is an area in medicine where medical sciences meet the realms of physics, engineering and technology. Therefore, it is paramount that attention is paid in the methodology of studies to the technical aspects in their full breadth. This paper provides an extensive introduction for non-technical researchers on how to describe and adjust their met...

Second-generation antidepressants for seasonal affective disorder

NeLM - Mental Health — Wed, 28 Dec 2011 05:00:00 +0100

Source: Cochrane Library Area: Evidence > Drug Class Focused Reviews Background Seasonal affective disorder (SAD) is a seasonal pattern of recurrent depressive episodes that is often treated with second-generation antidepressants (SGAs), light therapy or psychotherapy. Objectives To assess the efficacy and safety of SGAs for the treatment of SAD in adults in comparison with placebo, light therapy, other SGAs or psychotherapy. Search methods We searched the Cochrane Depression, Anxiety and Neuorosis Review Group's specialised register (CCDANCTR) on the 26 August 2011. The CCDANCTR contains reports of relevant randomised controlled trials from The Cochrane Library (all years), EMBASE (1974 to date), MEDLINE (1950 to date) and PsycINFO (1967...

Intense Pulsed-Light Therapy for Proliferative Haemangiomas of Infancy

Clinical and Developmental Immunology — Tue, 27 Dec 2011 23:55:03 +0100

Infantile haemangioma therapy has long been a wait-and-see policy. Since recent development of laser and light therapy, pulsed dye laser has been successfully used for treating superficial haemangiomas. Few studies have been published about treatment with intense pulsed light (IPL) to assess the risk/benefit of IPL in the treatment of infantile haemangiomas during their early proliferative phase. In the present retrospective cohort study, we retrieved data about a series of 14 Caucasian children (median age: 4.8 months) with infantile haemangiomas treated with Photoderm Vasculight flash lamp. All patients experienced a rapid regression of the haemangiomas after 3 treatments on average. Few adverse events were noted, including ulceration and crusts. No residual scarring and cosmetic damages...

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Second-generation antidepressants for seasonal affective disorder.

Cochrane Database of Systematic Reviews — Tue, 20 Dec 2011 01:00:04 +0100

CONCLUSIONS: Evidence for the effectiveness of SGAs is limited to one small trial of fluoxetine compared with placebo, which shows a non-significant effect in favour of fluoxetine, and two small trials comparing fluoxetine against light therapy, which suggest equivalence between the two interventions. The lack of available evidence precludes the ability to draw any overall conclusions on the use of SGAs for SAD. Further larger RCTs are required to expand and strengthen the evidence base on this topic, and should also include comparisons with psychotherapy and other SGAs.Data on adverse events were sparse, and a comparative analysis was not possible. Therefore the data we obtained on adverse effects is not robust and our confidence in the data is limited. Overall, up to 27% of participants ...

Ultraviolet-based therapy for vitiligo: What's new?

Indian Journal of Dermatology, Venereology and Leprology — Sat, 17 Dec 2011 05:00:00 +0100

Iltefat H Hamzavi, Henry W Lim, Zain U SyedIndian Journal of Dermatology, Venereology, and Leprology 2012 78(1):42-48Vitiligo is an ancient disease in which depigmented and hypopigmented macules appear on the skin. It is a disfiguring condition that may lead to severe psychological trauma. Among the many treatment modalities available for use in vitiligo, those using light therapy, and in particular ultraviolet (UV) light, are some of the most effective treatments. UV-based therapy includes phototherapy (narrowband UVB), photochemotherapy (psoralens with UVA), and targeted phototherapy (excimer laser and excimer lamp). It is important for any practitioner of UV-based therapy to understand the efficacy of each treatment type, as well as their respective adverse effects. In order to take ful...

Are You SAD This Winter? Coping with Seasonal Affective Disorder

Psych Central — Thu, 15 Dec 2011 22:35:54 +0100

Seasonal affective disorder (SAD) goes beyond the winter blues. It goes beyond feeling tired or sad or disliking winter. SAD is a form of clinical depression that occurs in the winter, according to Kelly Rohan, Ph.D, associate professor of psychology at the University of Vermont, whose research focuses on SAD. It starts around fall or winter, as the days get shorter and darker, and typically remits in the spring or summer. SAD affects around 14 million Americans, according to author and SAD specialist Norman E. Rosenthal, M.D., in his book Winter Blues: Everything You Need to Know to Beat Seasonal Affective Disorder. (About 14 percent of American adults struggle with the winter blues.) People with SAD experience a variety of physical, emotional and cognitive symptoms that impairs their da...

A Randomized Controlled Trial of Cognitive-Behavior Therapy Plus Bright Light Therapy for Adolescent Delayed Sleep Phase Disorder

Sleep — Fri, 02 Dec 2011 20:45:23 +0100

Conclusions:CBT plus BLT for adolescent DSPD is effective for improving multiple sleep and daytime impairments in the immediate and long-term. Studies evaluating the treatment effectiveness of each treatment component are needed.Clinical Trial Information:Australia – New Zealand Trials Registry Number: ACTRN12610001041044.Citation:Gradisar M; Dohnt H; Gardner G; Paine S; Starkey K; Menne A; Slater A; Wright H; Hudson JL; Weaver E; Trenowden S. A randomized controlled trial of cognitive-behavior therapy plus bright light therapy for adolescent delayed sleep phase disorder. SLEEP 2011;34(12):1671-1680. (Source: Sleep)

The effects of blue-enriched light treatment compared to standard light treatment in seasonal affective disorder

Journal of Affective Disorders — Thu, 01 Dec 2011 14:23:58 +0100

Conclusion: The lack of superiority of high intensity blue-enriched light over standard bright light treatment does not clearly support nor rule out the possibility of an important role for the circadian system or the blue sensitive non-visual image forming system in general, in the pathophysiology of SAD. The lack of a difference between conditions may also be the result of a saturated response to the high light intensities used. Recent data indeed suggest that low intensity blue-enriched light may be as effective as standard bright light treatment. The possibility of improving light therapy for SAD patients by applying light of shorter duration or at lower light intensities is highly relevant for optimizing treatment and will help to clarify the role of the circadian system and/or the no...

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[Sleep and its disorders in the elderly].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz — Mon, 28 Nov 2011 00:07:58 +0100

Authors: Happe S Abstract Restorative sleep is an important factor for preservation of health and quality of life. Sleep quality is associated with age, i.e., sleep disorders occur more frequently particularly after the age of 75 years. Furthermore, sleep shows an association with female gender, inactivity, dissatisfaction with social life, depressive symptoms, pain, intake of sedatives, genetic predisposition, and increased morbidity and mortality in the elderly. Strategies for improving sleep should include (1) effective treatment of organic diseases and mental disorders, (2) elimination of social life factors that impair sleep quality, (3) light therapy and other nonpharmacological treatment options for longer periods, and (4) short-term use of sleep medication as required. For...

Acceleration of the Meckel Syndrome by Near-Infrared Light Therapy

Karger Publishers — Thu, 24 Nov 2011 23:00:00 +0100

Nephron Extra 2011;1:224–234 (DOI:10.1159/000332046) (Source: Karger Publishers)

Boosting Your Serotonin Activity

Psychology Today Depression Center — Thu, 17 Nov 2011 17:05:04 +0100

Decreased serotonin activity can lead to feeling a little down, or having difficulty finishing things, or getting annoyed easily, or being impulsive. Fortunately there are several easy ways to boost serotonin that don't involve a prescription or buying "supplements" from some website in your spam folder. Primary Topic: Neuroscience read more (Source: Psychology Today Depression Center)

The Consumer: Light Boxes May Help Melt Those Winter Blues

NYT — Tue, 15 Nov 2011 18:50:07 +0100

Bright-light therapy is the treatment of choice for many Americans who suffer the winter blues, but many experts say it is underused. (Source: NYT)

Well Blog: Light Therapy for Dark Days

NYT Health — Mon, 14 Nov 2011 22:40:36 +0100

For the millions of Americans who suffer from mild to severe winter blues, bright-light therapy is the treatment of choice, with response rates comparable with those of antidepressants (Source: NYT Health)

Cure Winter Blues With Light Therapy

NPR Health and Science — Fri, 11 Nov 2011 18:00:00 +0100

Or The Beach — Seasonal depression, or seasonal affective disorder, affects some five percent of Americans in the winter as daily sunlight hours dwindle. Psychiatrist Richard A. Friedman discusses the evolutionary origins of the winter blues, and treatments ranging from light therapy to a trip to the beach.» E-Mail This » Add to Del.icio.us (Source: NPR Health and Science)

Shedding light on seasonal depression

The Irish Times - Health — Tue, 08 Nov 2011 12:10:38 +0100

MEDICAL MATTERS:Can light therapy relieve symptoms of Sad, writes MUIRIS HOUSTON (Source: The Irish Times - Health)

NIH researchers design a light therapy that targets and destroys cancer cells in mice

National Institutes of Health (NIH) News Releases — Mon, 07 Nov 2011 13:57:00 +0100

Researchers have designed a light-based therapy that allows the selective destruction of tumor cells in mice without harming surrounding normal tissue. This method of cancer therapy could theoretically work against tumors in humans, such as those of the breast, lung, prostate, as well as cancer cells in the blood such as leukemias, say scientists from the National Cancer Institute (NCI), part of NIH. (Source: National Institutes of Health (NIH) News Releases)

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The Nuts and Bolts of Low-level Laser (Light) Therapy.

Annals of Biomedical Engineering — Wed, 02 Nov 2011 04:00:00 +0100

Authors: Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR Abstract Soon after the discovery of lasers in the 1960s it was realized that laser therapy had the potential to improve wound healing and reduce pain, inflammation and swelling. In recent years the field sometimes known as photobiomodulation has broadened to include light-emitting diodes and other light sources, and the range of wavelengths used now includes many in the red and near infrared. The term "low level laser therapy" or LLLT has become widely recognized and implies the existence of the biphasic dose response or the Arndt-Schulz curve. This review will cover the mechanisms of action of LLLT at a cellular and at a tissular level and will summarize the various light sources and principles of dosimetry that...

Effect of 810 nm light on nerve regeneration after autograft repair of severely injured rat median nerve

Lasers in Surgery and Medicine — Thu, 20 Oct 2011 03:42:33 +0100

ConclusionThese results suggest that LT can accelerate functional recovery and improve the quality of nerve regeneration after autograft repair of severely injured peripheral nerves. Lasers Surg. Med. 43:901‐906, 2011. © 2011 Wiley Periodicals, Inc. (Source: Lasers in Surgery and Medicine)

Low-Level Laser Light Therapy Improves Cognitive Deficits and Inhibits Microglial Activation after Controlled Cortical Impact in Mice

Journal of Neurotrauma — Thu, 22 Sep 2011 03:12:09 +0100

Journal of Neurotrauma , Vol. 0, No. 0. (Source: Journal of Neurotrauma)

Latitude and psoriasis prevalence

Journal of the American Academy of Dermatology — Sun, 18 Sep 2011 01:35:52 +0100

To the Editor: Two important factors influencing psoriasis prevalence rates include climate and ethnicity, although these relationships are complicated. The ultraviolet index is of interest given the popular and effective treatment modality of light therapy, and known effects of weather patterns on psoriasis. (Source: Journal of the American Academy of Dermatology)

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Five medical apps the FTC will likely remove

mobihealthnews — Fri, 09 Sep 2011 18:03:09 +0100

This week the Federal Trade Commission made an unprecedented move to remove two medical apps from the Apple AppStore and Android Market on grounds that they made unsubstantiated efficacy claims. The apps both offered “light therapy” to treat a user’s acne. Both developers were ordered to pay back the monies they made by selling the [...] (Source: mobihealthnews)

Depression Scores Associate With Chronotype and Social Jetlag in a Rural Population.

Chronobiology International — Tue, 06 Sep 2011 04:00:00 +0100

Authors: Levandovski R, Dantas G, Fernandes LC, Caumo W, Torres I, Roenneberg T, Hidalgo MP, Allebrandt KV Abstract In public health, mood disorders are among the most important mental impairments. Patients with depressive episodes exhibit daily mood variations, abnormal patterns in sleep-wake behavior, and in the daily rhythms of several endocrine-metabolic parameters. Although the relationship between the sleep/circadian processes and mood disorders is poorly understood, clock-related therapies, such as light therapy, sleep deprivation, and rigid sleep schedules, have been shown to be effective treatments. Several studies investigated the relationship between circadian phenotype (chronotype) and depression. These focused mainly on urban populations and assessed diurnal preference...

Targeted 307 nm UVB‐phototherapy in psoriasis. A pilot study comparing a 307 nm excimer light with topical dithranol

Skin Research and Technology — Sat, 03 Sep 2011 23:00:00 +0100

ConclusionsThe 307 nm excimer light therapy for plaque type psoriasis was equipotent to twice daily topical dithranol. Efficacy, safety, and convenience suggest that targeted UVB therapy with quasi monochromatic light is a new useful treatment option for patients with limited psoriatic plaques. (Source: Skin Research and Technology)

[Polarized light acts as epigenetic factor in inhibition of inflammation; a genome wide expression analysis in recurrent respiratory diseases of children.]

Orvosi Hetilap — Thu, 01 Sep 2011 04:00:00 +0100

Conclusions: Improved clinical symptoms and modified gene expression profile of lymphocytes reveals anti-inflammatory effect upon whole body polarized light irradiation. Orv. Hetil., 2011, 152, 1492-1499. PMID: 21893480 [PubMed - as supplied by publisher] (Source: Orvosi Hetilap)

Effectiveness of environment-based interventions for people with Alzheimer's disease and related dementias.

The American Journal of Occupational Therapy — Thu, 01 Sep 2011 04:00:00 +0100

Authors: Padilla R Abstract A systematic review of evidence for the efficacy of environment-based interventions on the affect, behavior, and performance of people with Alzheimer's disease and related dementias was conducted as part of the American Occupational Therapy Association's Evidence-Based Literature Review Project. Thirty-three reports met inclusion criteria. Results suggest that ambient music, aromatherapy, and Snoezelen are modestly effective in reducingagitation but do not consistently have long-term effects. Visually complex environments that give the illusion of barriers deter people from wandering to unsafe places but do not reduce the urge to wander. Evidence that bright light therapy can aid in regulating mood and the sleep-wake cycle and thus help people remain awa...

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Shining a healing light on skin problems

The Irish Times - Health — Mon, 29 Aug 2011 23:50:15 +0100

Visible red veins can undermine confidence, but laser-light therapy offers a solution, writes ELEANOR FITZSIMONS (Source: The Irish Times - Health)

Intense Pulsed Light Therapy for Lupus Pernio.

Actas Dermo-Sifiliograficas — Thu, 25 Aug 2011 23:00:00 +0100

Authors: Rosende L, Del Pozo J, de Andrés A, Pérez Varela L PMID: 21872833 [PubMed - as supplied by publisher] (Source: Actas Dermo-Sifiliograficas)

Abnormal Hypothalamic Response to Light in Seasonal Affective Disorder. - Vandewalle G, Hébert M, Beaulieu C, Richard L, Daneault V, Garon ML, Leblanc J, Grandjean D, Maquet P, Schwartz S, Dumont M, Doyon J, Carrier J.

SafetyLit: All (Unduplicated) — Sat, 13 Aug 2011 04:06:57 +0100

BACKGROUND: Vulnerability to the reduction in natural light associated with fall/winter is generally accepted as the main trigger of seasonal affective disorder (SAD), whereas light therapy is a treatment of choice of the disorder. However, the relationshi... (Source: SafetyLit: All (Unduplicated))

Severe mood dysregulation: In the “light” of circadian functioning

Medical Hypotheses — Wed, 10 Aug 2011 04:00:00 +0100

Abstract: Severe affective and behavioral dysregulation, labeled as severe mood dysregulation (SMD), is a widely spread phenomenon among adolescent psychiatric patients. This phenotype constitutes severe impairment across multiple settings, including various symptoms, such as non-episodic anger, mood instability, and hyperarousal. Moreover, SMD patients often show depression and reduced need for sleep. Despite a lifetime prevalence of 3.3%, systematic research is still scarce, and treatments that have been established do not account for the range of symptoms present in SMD. Considering the circadian dysfunctions, two hormones, melatonin and cortisol, are essential. When these hormones are dysregulated, the circadian rhythm gets out of synchrony. Since evidence is emerging showing that the ...

Abnormal Hypothalamic Response to Light in Seasonal Affective Disorder

Biological Psychiatry — Mon, 08 Aug 2011 04:00:00 +0100

Conclusions: These results point to the posterior hypothalamus as the neurobiological substrate involved in specific aspects of SAD, including a distinctive response to light and altered emotional responses. (Source: Biological Psychiatry)

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Bright-Light Therapy in the Treatment of Mood Disorders

Neuropsychobiology : Last 20 articles — Thu, 28 Jul 2011 23:00:00 +0100

Neuropsychobiology 2011;64:152–162 (DOI:10.1159/000328950) (Source: Neuropsychobiology : Last 20 articles)

Genome-wide gene expression study indicates the anti-inflammatory effect of polarized light in recurrent childhood respiratory disease

Inflammation Research — Sun, 10 Jul 2011 05:52:23 +0100

Conclusions The improved clinical symptoms and modified gene expression profile of lymphocytes reveals an anti-inflammatory effect of whole-body polarized light irradiation. Content Type Journal ArticlePages 1-8DOI 10.1007/s00011-011-0357-yAuthors A. Falus, Department of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, HungaryM. Fenyő, Polárium Ltd, Budapest, HungaryK. Éder, Department of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, 1089 Budapest, HungaryA. Madarasi, Szt. János Hospital, Budapest, Hungary Journal Inflammation ResearchOnline ISSN 1420-908XPrint ISSN 1023-3830 (Source: Inflammation Research)

In Vitro Evaluation of Chloroaluminum Phthalocyanine Nanoemulsion and Low-Level Laser Therapy on Human Skin Dermal Equivalents and Bone Marrow MesenchymalStem Cells.

Current Medicinal Chemistry — Sun, 03 Jul 2011 23:00:00 +0100

This article describes the preparation of a nanocarrier for the controlled release of a photosensitizer compound associated with low-level light therapy for skin wound healing treatment and applicable to other skin diseases. A biological model was used as an in vitro skin equivalent based on a three-dimensional culture of fibroblasts and mesenchymal stem cells and denominated by dermal equivalent (DE). Results show that it is possible to use the photomodulation process to control the wound healing in a scratching process and to induce the biomolecules release, both of which are related with the inflammatory wound healing process. In the studies, the MMP-2 and MMP-9 expression from zymography analyses were evaluated. All results showed a dependence on enzymatic activity relating to lowlevel...

Amelioration of oral mucositis pain by NASA near-infrared light-emitting diodes in bone marrow transplant patients

Supportive Care in Cancer — Sat, 02 Jul 2011 21:31:40 +0100

Conclusion Phototherapy demonstrated a significant reduction in patient-reported pain as measured by the WHO criteria in this patient population included in this study. Improvement trends were noted in most other assessment measurements. Content Type Journal ArticlePages 1-11DOI 10.1007/s00520-011-1223-8Authors Brian D. Hodgson, Pediatric Dentistry, Marquette University School of Dentistry, 1801 W. Wisconsin Ave., Rm. 326, Milwaukee, WI 53233, USADavid M. Margolis, Pediatric Oncology, Medical College of Wisconsin, 8701 Watertown Plank Road, Wauwatosa, WI 53226, USADonna E. Salzman, Education and Clinical Services BMT Program, University of Alabama at Birmingham, 2000 6th Avenue South, Birmingham, AL 35233, USADan Eastwood, Division of Biostatistics, Medical College o...

Laser and intense pulsed light therapy for the treatment of hypertrophic scars: a systematic review

British Journal of Dermatology — Mon, 27 Jun 2011 23:00:00 +0100

AbstractHypertrophic scars are difficult to improve and remain a therapeutic challenge. Several lasers and light sources were evaluated in the past decades and showed to improve hypertrophic scars. However, a systematic review is not available. To assess current evidence of efficacy of all laser and intense pulsed light therapies used in the treatment of hypertrophic scars, we performed a systematic review searching electronic databases MEDLINE, EMBASE and CENTRAL. The quality of the controlled clinical trials was evaluated according to the Cochrane Collaboration’s tool for assessing risk of bias. Thirteen articles involving seven different lasers met the inclusion criteria. Most evidence was found for the pulsed dye laser (PDL) 585 nm (8 studies), followed by the PDL 595 nm (2 studies),...

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Laser and intense pulsed light therapy for the treatment of hypertrophic scars: a systematic review.

The British Journal of Dermatology — Mon, 27 Jun 2011 23:00:00 +0100

Authors: Vrijman C, van Drooge AM, Limpens CE, Bos JD, van der Veen JP, Spuls PI, Wolkerstorfer A Hypertrophic scars are difficult to improve and remain a therapeutic challenge. Several lasers and light sources were evaluated in the past decades and showed to improve hypertrophic scars. However, a systematic review is not available. To assess current evidence of efficacy of all laser and intense pulsed light therapies used in the treatment of hypertrophic scars, we performed a systematic review searching electronic databases MEDLINE, EMBASE and CENTRAL. The quality of the controlled clinical trials was evaluated according to the Cochrane Collaboration's tool for assessing risk of bias. Thirteen articles involving seven different lasers met the inclusion criteria. Most evidence was foun...

Depot Based Drug Delivery System for the Management of Depression - A Review.

Current Drug Delivery — Tue, 21 Jun 2011 23:00:00 +0100

Authors: Pilaniya U, Khatri K, Patil UK Depression is a common mental disorder discerns with depressed mood, loss of interest, the primary treatment methods are drug therapy, electroconvulsive therapy, psychotherapy, light therapy, vagus nerve stimulation, etc. A number of innovative delivery systems have been developed to address suboptimal therapy outcomes by enhancing drug delivery, assuring efficacy of treatment, reducing side effects, improving compliance and drug targeting specific locations resulting in a higher efficiency. Depot delivery offers the advantage of a very high loading, controlled release of drug for an extended period of time and reduces frequency of dosing. The increase in AUC and decrease in Cmax reflects that the depot formulations could reduce the toxic complic...

Light Therapy for Seniors in Long Term Care

Journal of the American Medical Directors Association — Fri, 17 Jun 2011 04:00:00 +0100

Conclusion: Blue light treatment led to significant cognitive improvements compared with placebo red light and may be a promising environmental intervention to reduce cognitive symptoms in elderly, long-term care residents. (Source: Journal of the American Medical Directors Association)

Efficacy of excimer light therapy (308 nm) for palmoplantar pustulosis with the induction of circulating regulatory T cells

Experimental Dermatology — Mon, 13 Jun 2011 23:00:00 +0100

Abstract: In this open‐label study, we investigated the efficacy of excimer light (308 nm) with a filter to cut off wavelengths below 297 nm for the treatment of palmoplantar pustulosis (PPP). Twenty patients with PPP were recruited and treated once a week for a total of 30 sessions. Patient response was assessed every 10 sessions based on the Palmoplantar Pustulosis Area and Severity Index (PPPASI) score. Levels of Th17 cells and regulatory T cells (Treg) in the peripheral blood in patients with PPP were also evaluated. Mean PPPASI score was 19.5 at baseline, 13.2 at 10 treatments, 10.9 at 20 treatments and 9.5 at 30 treatments. Th17 levels after excimer therapy were not significantly different from those at baseline. In contrast, Treg levels after excimer therapy were significan...

Improvement in Fatigue, Sleepiness, and Health-Related Quality of Life with Bright Light Treatment in Persons with Seasonal Affective Disorder and Subsyndromal SAD

Anesthesiology Research and Practice — Mon, 13 Jun 2011 14:17:40 +0100

Conclusion. Fatigue, excessive daytime sleepiness, and health-related quality of life improve in a similar way as depressed mood following treatment with bright light. The treatment was effective irrespective of the severity of the disorder, that is, for persons with SAD and subsyndromal SAD. (Source: Anesthesiology Research and Practice)

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Principles and Practice of Cutaneous Laser and Light Therapy

Clinics in Plastic Surgery — Sun, 05 Jun 2011 23:00:00 +0100

Laser technology has evolved rapidly in the last 2 decades. The theory of selective photothermolysis guides the proper selection and use of lasers to safely and effectively treat patients. This review summarizes the basic concepts and adjustable parameters for laser devices, emphasizing the importance of selective photothermolysis in clinical practice. It then covers the clinical applications of laser devices, including vascular lesions, hair removal, tattoo removal, facial rejuvenation, and fractional resurfacing. The authors intend to make the reader feel comfortable with the proper selection and application of lasers to treat their patients. (Source: Clinics in Plastic Surgery)

Effectiveness of light therapy for depression among active duty service members: A nonrandomized controlled pilot trial.

Complementary Therapies in Medicine — Tue, 31 May 2011 23:00:00 +0100

Authors: Lande RG, Williams LB, Gragnani C, Albert Tsai The authors investigated the potential effectiveness of light therapy as an augmentation treatment for depression among active duty service members. PMID: 21641522 [PubMed - in process] (Source: Complementary Therapies in Medicine)

Mother Nature's Impact on Mood and Creativity

Psychology Today Depression Center — Wed, 18 May 2011 21:19:58 +0100

Sometimes weather blues can be a benefit for creativity.read more (Source: Psychology Today Depression Center)

Stroke Survivors Recovering Lost Vision With Non-Invasive Light Therapy

Health News from Medical News Today — Fri, 13 May 2011 15:00:00 +0100

Statistics show that stroke is a leading cause of serious long-term disability and, although each person is unique, stroke can affect people similarly with comparable disabilities such as partial blindness due to visual field loss - a condition previously believed to be untreatable. In honor of National Stroke Awareness Month, NovaVision, Inc... (Source: Health News from Medical News Today)

Vitamin D Treatments Target Psoriasis

WebMD Health — Thu, 12 May 2011 23:46:27 +0100

Ultraviolet light therapy and vitamin D creams are widely prescribed treatments for psoriasis, and now a new study may help explain why they work for so many patients. (Source: WebMD Health)

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The usefulness of bright light therapy for patients after oesophagectomy

Intensive and Critical Care Nursing — Mon, 09 May 2011 15:42:49 +0100

Conclusion: We conclude that postoperative bright light exposure adjusted the sleep–wakefulness cycle and improved the bed rest of patients. It was also indicated that bright light therapy is useful for reducing postoperative delirium. (Source: Intensive and Critical Care Nursing)

Ocular hazards of blue-light therapy in dermatology

Journal of the American Academy of Dermatology — Tue, 03 May 2011 04:00:00 +0100

Blue-light phototherapy has become important in the treatment of many dermatologic conditions and as a result continue to be developed. Although blue-light therapy is successful, research shows that excessive ocular blue-light exposure may contribute to age-related macular degeneration and other vision problems. As blue-light therapy becomes increasingly more popular for clinical and at-home use, patients and operators of blue-light devices should be aware of its associated ocular hazards. Protective eyewear should be carefully selected and implemented with each therapy session to guard against the development of retinal disease. (Source: Journal of the American Academy of Dermatology)

Vitamin D Deficiency in Patients Receiving Home Parenteral Nutrition.

JPEN Journal Of Parenteral And Enteral Nutrition — Mon, 02 May 2011 23:00:00 +0100

CONCLUSIONS: In this study of a regional Canadian HPN program, there was a high prevalence of vitamin D deficiency/insufficiency affecting virtually all patients. All patients receiving HPN should be supplemented with vitamin D and have their 25-hydroxyvitamin D levels monitored. Further studies are required to determine optimal methods and dosing of vitamin D replacement using oral supplements or ultraviolet light therapy. (JPEN J Parenter Enteral Nutr. XXXX;xx:xx-xx). PMID: 21540352 [PubMed - as supplied by publisher] (Source: JPEN Journal Of Parenteral And Enteral Nutrition)

Dermaplaning, Topical Oxygen, and Photodynamic Therapy: A Systematic Review of the Literature

Aesthetic Plastic Surgery — Mon, 02 May 2011 05:42:55 +0100

Conclusion Although the evidence supporting these nonsurgical methods is suboptimal, their uses continue to expand. As with any plastic surgery procedure, providing patients with realistic expectations is essential to achieving optimal outcomes and patient satisfaction. Therefore, critical investigation is warranted. In addition, these methods are most effective when included within a comprehensive skin care regimen consisting of sunscreen, vitamin therapy, and lifestyle modification. Content Type Journal ArticlePages 1-9DOI 10.1007/s00266-011-9730-zAuthors Landon Pryor, Plastic and Reconstructive Surgery, Rockford Health System, Rockford, IL 61103, USAChad R. Gordon, Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH, USAEdward W. Swanson, Division of ...

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Bright light treatment of depressive symptoms in patients with restrictive type of anorexia nervosa

Journal of Affective Disorders — Fri, 29 Apr 2011 23:09:06 +0100

Conclusions: The results obtained may suggest that BLT could be an effective non-pharmacological modality for the treatment of depression in patients with AN-R. (Source: Journal of Affective Disorders)

Blue light therapy for basal cell carcinoma has benefits, drawbacks

Modern Medicine — Fri, 29 Apr 2011 22:22:27 +0100

Results of a recent study to determine the effectiveness of noncoherent blue light in the intralesional photodynamic therapy (PDT) of basal cell carcinoma (BCC) found the treatment to be beneficial for a certain subgroup of patients. (Source: Modern Medicine)

Light therapy may help depression in pregnancy

Reuters: Health — Thu, 21 Apr 2011 16:20:55 +0100

NEW YORK (Reuters Health) - Light therapy may improve symptoms in pregnant women with depression, suggests a new study of 27 women in Switzerland. (Source: Reuters: Health)

Circadian Rhythms, Melatonin and Depression.

Current Pharmaceutical Design — Thu, 07 Apr 2011 23:00:00 +0100

Authors: Quera Salva MA, Hartley S, Barbot F, Alvarez JC, Lofaso F, Guilleminault C The master biological clock situated in the suprachiasmatic nuclei of the anterior hypothalamus plays a vital role in orchestrating the circadian rhythms of multiple biological processes. Increasing evidence points to a role of the biological clock in the development of depression. In seasonal depression and in bipolar disorders it seems likely that the circadian system plays a vital role in the genesis of the disorder. For major unipolar depressive disorder (MDD) available data suggest a primary involvement of the circadian system but further and larger studies are necessary to conclude. Melatonin and melatonin agonists have chronobiotic effects, which mean that they can readjust the circadian system. ...

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Noninvasive cutaneous blood flow as a response predictor for visible light therapy on segmental vitiligo: a prospective pilot study

British Journal of Dermatology — Thu, 31 Mar 2011 23:00:00 +0100

Conclusions Normalization of sympathetic dysfunction may account for the efficacy of visible light in treating SV. Evaluation of cutaneous blood flow with and without prior visible light irradiation on cold‐stressed SV lesions may serve as a treatment response predictor. (Source: British Journal of Dermatology)

Light Therapy May Aid Traumatic Brain Injury (CME/CE)

MedPage Today Neurology — Sun, 20 Mar 2011 21:46:25 +0100

(MedPage Today) -- Two patients with long-term deficits from traumatic brain injury (TBI) have shown substantial improvement in cognitive function with transcranial light therapy, investigators reported. (Source: MedPage Today Neurology)

Transcranial LED-Based Light Therapy Effective Self-Administered Treatment For Traumatic Brain Injury

Health News from Medical News Today — Sat, 19 Mar 2011 07:00:00 +0100

At-home, daily application of light therapy via light-emitting diodes (LEDs) placed on the forehead and scalp led to improvements in cognitive function and post-traumatic stress disorder in patients with a traumatic brain injury (TBI), according to a groundbreaking study published in Photomedicine and Laser Surgery, a peer-reviewed journal published by Mary Ann Liebert, Inc. The article is available free online here... (Source: Health News from Medical News Today)

Self-administered light therapy may improve cognitive function after traumatic brain injury

EurekAlert! - Medicine and Health — Thu, 17 Mar 2011 04:00:00 +0100

(Mary Ann Liebert, Inc./Genetic Engineering News) At-home, daily application of light therapy via light-emitting diodes placed on the forehead and scalp led to improvements in cognitive function and post-traumatic stress disorder in patients with a traumatic brain injury, according to a groundbreaking study published in Photomedicine and Laser Surgery, a peer-reviewed journal published by Mary Ann Liebert Inc. (Source: EurekAlert! - Medicine and Health)

Laser treatment for late-stage cancer

Chemistry World | Latest News — Sat, 05 Mar 2011 07:43:42 +0100

Light therapy could be used to treat cancer after it has spread to other areas in the body (Source: Chemistry World | Latest News)

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Recalcitrant Palmoplantar Pustular Psoriasis Treated with Etanercept

Pediatric Dermatology — Thu, 03 Mar 2011 00:00:00 +0100

We report a 10‐year‐old boy presenting with palmoplantar pustular psoriasis, resistant to topical and systemic treatments, who was successfully treated with subcutaneous etanercept (0.4 mg/kg) twice a week for 1 month. Maintenance therapy was extended for 18 months in combination with near ultraviolet light therapy without any adverse effect. Etanercept may be a safe and effective alternative for severe palmoplantar pustular psoriasis in children. (Source: Pediatric Dermatology)

Does outdoor work during the winter season protect against depression and mood difficulties?

Scandinavian Journal of Work, Environment and Health — Tue, 01 Mar 2011 00:00:00 +0100

CONCLUSION: Our study is limited by its cross-sectional design and low statistical power but nevertheless suggests that outdoor work during winter may protect against mood difficulties. If this finding holds true it may have significant impact on workers' health as well as public health in general. Therefore, further studies are recommended. PMID: 21359494 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Work, Environment and Health)

Light therapy as a treatment for epilepsy

Medical Hypotheses — Fri, 18 Feb 2011 00:00:00 +0100

Abstract: From a neurobiological level to epidemiological studies, there are four strands of evidence in the scientific literature that indicate that light therapy could be an effective treatment for some people with epilepsy.(1) Sunlight is important in the endogenous production and regulation of melatonin and vitamin D, both of which influence seizure thresholds. Although melatonin influences seizure thresholds, the relationship is complex. General down-regulating effects may have different effects on seizure thresholds for people with generalised and partial epilepsy syndromes. Specific actions within the hippocampus may mean that patients with temporal lobe epilepsy are particularly susceptible to the endogenous expression of melatonin via inhibitory actions on dopaminergic activity re...

Circadian Rhythm Sleep Disorder, Free-Running Type in a Sighted Male with Severe Depression, Anxiety, and Agoraphobia

Journal of Clinical Sleep Medicine : JCSM — Tue, 15 Feb 2011 12:50:08 +0100

Circadian rhythm sleep disorder, free-running type (CRSD, FRT) is a disorder in which the intrinsic circadian rhythm is no longer entrained to the 24-hour schedule. A unique case of CRSD, FRT in a 67-year-old sighted male is presented. The patient had a progressively delayed time in bed (TIB) each night, so that he would cycle around the 24-h clock approximately every 30 days. This was meticulously documented each night by the patient over the course of 22 years. The patient’s CRSD, FRT was associated with severe depression, anxiety, and agoraphobia. The agoraphobia may have exacerbated the CRSD, FRT. Entrainment and stabilization of his circadian rhythm was accomplished after treatment that included melatonin, light therapy, and increased sleep structure. Keywords: Circadian rhythm...

Light therapy, circa 1939

The Scientist — Tue, 01 Feb 2011 08:00:00 +0100

Before the damaging effects of UV radiation were widely appreciated, physicians saw the sun mostly as a source of healing (Source: The Scientist)

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Dora Colebrook and the evaluation of light therapy.

J R Soc Med AND (has... — Tue, 01 Feb 2011 00:00:00 +0100

Authors: Edwards M PMID: 21282799 [PubMed - in process] (Source: J R Soc Med AND (has...)

Light Therapy For Early-Stage Laryngeal Cancer Is A Voice-Saver

Health News from Medical News Today — Mon, 31 Jan 2011 10:00:00 +0100

Light, or photodynamic, therapy can help preserve the voice and vocal cord function for patients with early stage laryngeal (voice box) cancer, according to a study from Henry Ford Hospital in Detroit. "Photodynamic therapy is an effective treatment for early laryngeal squamous cell carcinomas, offering patients a less invasive option with fewer side effects than other therapies, while preserving the voice," says study co-author Vanessa G. Schweitzer, FACS, M.D., a senior staff physician in the Department of Otolaryngology-Head & Neck Surgery at Henry Ford. The study was presented Jan... (Source: Health News from Medical News Today)

Dora Colebrook and the evaluation of light therapy

JRSM — Mon, 31 Jan 2011 00:00:00 +0100

(Source: JRSM)

Voice-saver: Light therapy for early-stage laryngeal cancer

ScienceDaily Headlines — Sat, 29 Jan 2011 16:00:00 +0100

A new study finds light, or photodynamic therapy, can help preserve the voice in patients with early stage laryngeal cancer. Photodynamic therapy works by destroying deadly cancer cells without harming surrounding healthy tissue by using a powerful laser and a nontoxic, light-activated drug. It also has fewer side-effects than radiation and surgery. (Source: ScienceDaily Headlines)

Light Therapy for Early Stage Laryngeal Cancer is Voice Saver

Disabled World — Fri, 28 Jan 2011 18:04:02 +0100

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Garden weed extract 'fights skin cancer'

NHS News Feed — Fri, 28 Jan 2011 17:00:00 +0100

Conclusion This phase I study has demonstrated the clinical effects of the Euphorbia peplus extract in patients with non-melanoma skin cancers for whom surgery was either not desirable or appropriate. This is early research that has not yet compared this new treatment with others. It does however form an important step on the pathway to developing PEP500 into an established treatment. The positive results mean that larger, comparative research will follow. There are two main types of skin cancer: malignant melanomas, which are less common but more serious, and non-melanoma skin cancers, which are very common, especially in older age groups. About three-quarters of non-melanoma skin cancers are basal cell and the remainder are squamous cell carcinoma, both of which are associated with sun ...

Voice-saver: Light therapy for early-stage laryngeal cancer

EurekAlert! - Medicine and Health — Fri, 28 Jan 2011 05:00:00 +0100

(Henry Ford Health System) A new study from researchers at Henry Ford Hospital finds light, or photodynamic therapy, can help preserve the voice in patients with early stage laryngeal cancer. Photodynamic therapy works by destroying deadly cancer cells without harming surrounding healthy tissue by using a powerful laser and a nontoxic, light-activated drug. It also has fewer side-effects than radiation and surgery. (Source: EurekAlert! - Medicine and Health)

Bright Light Treatment May Improve Nonseasonal Depressive Symptoms

Medscape Today Headlines — Fri, 21 Jan 2011 14:54:46 +0100

A new study suggests bright light therapy improves both mood and sleep efficiency in elderly patients with nonseasonal major depressive disorder. Medscape Medical News (Source: Medscape Today Headlines)

Estimation of Human Circadian Phase via a Multi-Channel Ambulatory Monitoring System and a Multiple Regression Model

Journal of Biological Rhythms — Thu, 20 Jan 2011 00:00:00 +0100

Reliable detection of circadian phase in humans using noninvasive ambulatory measurements in real-life conditions is challenging and still an unsolved problem. The masking effects of everyday behavior and environmental input such as physical activity and light on the measured variables need to be considered critically. Here, we aimed at developing techniques for estimating circadian phase with the lowest subject burden possible, that is, without the need of constant routine (CR) laboratory conditions or without measuring the standard circadian markers, (rectal) core body temperature (CBT), and melatonin levels. In this validation study, subjects (N = 16) wore multi-channel ambulatory monitoring devices and went about their daily routine for 1 week. The devices measured a large number of ph...

Use of complementary and alternative medicine at Norwegian and Danish hospitals

BMC Complementary and Alternative Medicine — Tue, 18 Jan 2011 00:00:00 +0100

Conclusions: The extent of CAM being offered has increased substantially in Norway during the first decade of the 21st century. This might indicate a shift in attitude regarding CAM within the conventional health care system. (Source: BMC Complementary and Alternative Medicine)

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What is the Dose of Light Therapy for Seasonal Affective Disorder?

PediatricEducation.org — Mon, 17 Jan 2011 00:19:22 +0100

Discussion Seasonal affective disorder was first systematically described in 1984. It can occur at different times of the year but predominantly winter and less commonly summer. The DSM IV criteria includes: There is a temporal relationship between the onset of major depressive episodes and a particular time of year. Full remissions (or a change from depression to mania or hypomania) also occur at a characteristic time of year. In the last two years, two major depressive episodes have occurred that demonstrate the temporal seasonal relationships defined in the two criteria above and no nonseasonal major depressive episodes have occurred during the same period. Seasonal major depressive episodes substantially outnumber the nonseasonal major depressive episodes that may have occurred over t...

Casting Good Light for Senior Mood

Psychology Today Depression Center — Thu, 13 Jan 2011 22:33:10 +0100

It is well known that in the senior population, many factors can contribute to poor mood: low nutrient status, hormonal imbalance, changes of life, other health conditions, and loss of loved ones.One study from the Netherlands suggests that changes in circadian rhythm and how your brain's biological clock operates can also play an important role. A recent study of 89 depressed patients over the age of 60 years were split into two groups: one group was given 1 hour of either 7500 lux bright pale blue light therapy in the morning or dim red light, as a control. The elderly patients who had the blue light therapy had better mood, better sleep, and a more balance melatonin response. Melatonin is the hormone released in the early evening when the outside light dims. This hormone is a cruci...

The Use of 808-nm Light Therapy to Treat Experimental Chronic Osteomyelitis Induced in Rats by Methicillin-Resistant Staphylococcus Aureus

Photomedicine and Laser Surgery — Tue, 11 Jan 2011 04:42:12 +0100

Photomedicine and Laser Surgery , Vol. 0, No. 0. (Source: Photomedicine and Laser Surgery)

The Human Circadian System Adapts to Prior Photic History.

The Journal of Physiology — Mon, 10 Jan 2011 00:00:00 +0100

Authors: Chang AM, Scheer FA, Czeisler CA Light is the most potent stimulus for synchronizing the endogenous circadian timing system to the 24-hour day. The timing, intensity, duration, pattern, and wavelength of light are known to modulate photic resetting of the circadian system and acute suppression of melatonin secretion. The effect of prior photic history on these processes, however, is not well understood. Although previous studies have shown that light history affects the suppression of melatonin in response to a subsequent light exposure, here, we show for the first time that a very dim light history, as opposed to a typical indoor room illuminance, amplifies the phase-shifting response to a subsequent sub-saturating light stimulus by 60-70%. This greater efficacy provides evid...

Well: Light Therapy for Depression

NYT Health — Thu, 06 Jan 2011 21:15:11 +0100

Light therapy is typically recommended for seasonal affective disorder, but more patients with depression may benefit from the treatment. (Source: NYT Health)

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Light Therapy May Brighten Up Depressed Seniors (CME/CE)

MedPage Today Geriatrics — Tue, 04 Jan 2011 01:43:02 +0100

(MedPage Today) -- Literally shining a light on a darkened mind may help older patients with major depression -- with three weeks of home-based light therapy producing a significant improvement in mood and sleep, according to the results of a Dutch randomized trial. (Source: MedPage Today Geriatrics)

Is Blue Light Bad for SAD?

Dr. Weil Q and A — Thu, 30 Dec 2010 09:23:20 +0100

I was disturbed to read that treating SAD with blue light may cause retinal damage. I've been using light therapy for years, and my current light "box" gives off blue light. Can you provide additional information on this issue? (Source: Dr. Weil Q and A)

A randomized controlled trial of visible-light therapy for the prevention of oral mucositis

Oral Oncology — Fri, 17 Dec 2010 00:00:00 +0100

The objective of this study was to assess the efficacy of a novel visible-light therapy (VLT) device for the prevention of oral mucositis in hematopoietic stem cell transplantation (HSCT) patients. A VLT-device suitable for intra-oral use was applied to 20 patients undergoing HSCT. The study design was placebo-controlled, randomized and double-blind. Oral mucositis was assessed using the OMAS and WHO scales. Oral pain and acceptance levels were scored by the patient using a 10-step scale. Patients were evaluated once a week until day 21 post-HSCT. Mucositis rate, severity and pain score were compared. At the third visit, 1week post-HSCT, mucositis rates were significantly lower in the treatment group (for both WHO and OMAS p=0.02). Mucositis was also less severe in the treatment group (for...

Future research into the treatment of vitiligo: where should our priorities lie? Results of the vitiligo priority setting partnership

British Journal of Dermatology — Fri, 03 Dec 2010 00:00:00 +0100

Conclusions: The top ten research areas for the treatment of vitiligo provide guidance for researchers and funding bodies, to ensure that future research answers questions that are important to both clinicians and patients. (Source: British Journal of Dermatology)

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Future research into the treatment of vitiligo: where should our priorities lie? Results of the vitiligo priority setting partnership.

The British Journal of Dermatology — Fri, 03 Dec 2010 00:00:00 +0100

Beat the Blues This Winter

Al Sears, MD Natural Remedies — Wed, 24 Nov 2010 08:37:32 +0100

Dear Health Conscious Reader, Your body depends on getting enough sunlight every day to function properly. Nature designed you that way. Our ancestors lived outdoors every moment of their lives. They hunted meat, fish and fowl. They ate, worked, gathered, celebrated, worshipped and mourned under the sun. So your cells, organs, bones and tissues evolved to rely on sunlight. But just before the turn of the 20th century, our living conditions changed. It started with the invention of the light bulb, which gave us an artificial way to generate light. The industrial revolution soon followed, and people started migrating to the cities and working indoors. This migration indoors combined with modern medical advice has altered our native relationship with the sun forever. Modern medicine tells yo...

A Canadian online survey to evaluate awareness and treatment satisfaction in individuals with moderate to severe plaque psoriasis

International Journal of Dermatology — Wed, 24 Nov 2010 04:16:15 +0100

Conclusions Most respondents with moderate to severe psoriasis were unaware of all treatment options; systemic treatments were not commonly utilized. Treatment satisfaction rates were low, highlighting the need to ensure greater patient education on and use of available therapeutic options. (Source: International Journal of Dermatology)

Therapeutics for Circadian Rhythm Sleep Disorders

Sleep Medicine Clinics — Tue, 23 Nov 2010 05:44:31 +0100

The sleep-wake cycle is regulated by the interaction of endogenous circadian and homeostatic processes. The circadian system provides timing information for most physiologic rhythms, including the sleep and wake cycle. In addition, the central circadian clock located in the suprachiasmatic nucleus of the hypothalamus has been shown to promote alertness during the day. Circadian rhythm sleep disorders arise when there is a misalignment between the timing of the endogenous circadian rhythms and the external environment, or when there is dysfunction of the circadian clock or its entrainment pathways. The primary synchronizing agents of the circadian system are light and melatonin. Light is the strongest entraining agent of circadian rhythms, and timed exposure to bright light is often used in...

Intense Pulsed Light Therapy

Obstetrics and Gynecology Clinics — Sat, 20 Nov 2010 10:41:16 +0100

Intense Pulsed Light (IPL) is an FDA-approved photo therapy for the treatment of a variety of conditions such as acne and hirsutism. It utilizes the principle of selective photothermolysis. Photothermolysis allows a specific wavelength to be delivered to a chromophore of a designated tissue while leaving the surrounding tissue unaffected. The results of IPL are similar to that of laser treatments but it offers the advantage of a relative low cost. It is a safe and rapid treatment with minimal discomfort to the patient. (Source: Obstetrics and Gynecology Clinics)

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Noninvasive cutaneous blood flow assessment as a response predictor for visible light therapy on segmental vitiligo: A prospective pilot study

British Journal of Dermatology — Fri, 19 Nov 2010 05:07:20 +0100

Conclusions: Normalization of sympathetic dysfunction may be accountable for visible light’s efficacy on treating SV. Evaluation of cutaneous blood flow with or without prior visible light irradiation on cold‐stressed SV lesions may serve as a treatment response predictor. (Source: British Journal of Dermatology)

Noninvasive cutaneous blood flow assessment as a response predictor for visible light therapy on segmental vitiligo: A prospective pilot study.

The British Journal of Dermatology — Thu, 18 Nov 2010 00:00:00 +0100

Conclusions: Normalization of sympathetic dysfunction may be accountable for visible light's efficacy on treating SV. Evaluation of cutaneous blood flow with or without prior visible light irradiation on cold-stressed SV lesions may serve as a treatment response predictor. PMID: 21087230 [PubMed - as supplied by publisher] (Source: The British Journal of Dermatology)

Spectral quality of light modulates emotional brain responses in humans [Neuroscience]

Proceedings of the National Academy of Sciences — Tue, 09 Nov 2010 00:00:00 +0100

Light therapy can be an effective treatment for mood disorders, suggesting that light is able to affect mood state in the long term. As a first step to understand this effect, we hypothesized that light might also acutely influence emotion and tested whether short exposures to light modulate emotional brain responses. During functional magnetic resonance imaging, 17 healthy volunteers listened to emotional and neutral vocal stimuli while being exposed to alternating 40-s periods of blue or green ambient light. Blue (relative to green) light increased responses to emotional stimuli in the voice area of the temporal cortex and in the hippocampus. During emotional processing, the functional connectivity between the voice area, the amygdala, and the hypothalamus was selectively enhanced in the...

Stelara (ustekinumab) and Remicade (infliximab) are effective if Enbrel (etanercept) stops working in psoriasis

Clinical Cases and Images — Thu, 28 Oct 2010 13:46:00 +0100

About 7.5 million Americans suffer from psoriasis, a lifelong disorder characterized by inflammation of skin and, often, the joints.Stelara, Remicade, and Enbrel are all biologics -- drugs made of genetically engineered proteins -- that are generally used to treat patients who aren't responding to traditional therapies such as light therapy and methotrexate.Remicade and Enbrel both block tumor necrosis factor-alpha (TNF-alpha), a chemical produced by immune cells that fuels inflammation, much like gas on a fire. Stelara targets two proteins, interleukin 12 and interleukin 23, that also drive the inflammatory process.References:Study Shows Stelara and Remicade Are Both Effective if Enbrel Stops Working. WebMD, 2010.Image source: Crystal structure of human IL-12, Wikipedia, public domain. ...

Types of Hair Loss and Treatment Options, Including the Novel Low-Level Light Therapy and Its Proposed Mechanism

Medscape Today Headlines — Thu, 07 Oct 2010 11:38:42 +0100

An overview of the mechanisms of low-level light therapy, a promising new approach to treatment of hair loss in both men and women. Southern Medical Journal (Source: Medscape Today Headlines)

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Seasonal affective disorder treatment: Choosing a light box

MayoClinic.com Full Feed — Fri, 01 Oct 2010 05:00:00 +0100

Seasonal affective disorder treatment — Get tips for choosing a light therapy box. (Source: MayoClinic.com Full Feed)

Broadband light therapy fights signs of skin aging

Modern Medicine — Thu, 30 Sep 2010 23:00:00 +0100

It is well-documented that intense pulsed light (IPL) is effective in skin rejuvenation. Spanning a wider visible spectrum, broadband light (BBL) is at least as effective, and though some may be skeptical, one expert says years of IPL or BBL treatment can be effective for combating skin aging. (Source: Modern Medicine)

Socioeconomic factors outweigh climate in the regional difference of suicide death rate in Taiwan

Psychiatry Research — Thu, 02 Sep 2010 09:53:52 +0100

Abstract: The present study explored both socioeconomic and climatic factors to obtain a more comprehensive view of the asymmetric regional suicide death rate during 1998–2006 in Taiwan. The annual suicide death rate, population and meteorological data from 19 cities/counties in Taiwan were analysed by multiple regression. Five socioeconomic (sex ratio, no spouse, aged, unemployment and low income) and three climatic (temperature, rainfall and sunshine) factors were identified as significant, explaining 59.0% of the variance in the total suicide death rate. ‘Without spouse’ and ‘aged’ were associated with the highest risk, while ‘low income with financial aids’ was strongly protective. The most influential climatic factor was ‘temperature,’ which was negatively correlated...

Clinical Inquiries: Does exercise alleviate symptoms of depression?

The Journal of Family Practice — Tue, 31 Aug 2010 23:00:00 +0100

Authors: Gill A, Womack R, Safranek S Yes. Exercise reduces patient-perceived symptoms of depression when used as monotherapy (strength of recommendation [SOR]: B, meta-analysis of randomized controlled trials [RCTs] with significant heterogeneity). It relieves symptoms as effectively as cognitive behavioral therapy (CBT) or pharmacologic anti-depressant therapy (SOR: B, meta-analysis) and more effectively than bright light therapy (SOR: B, meta-analysis). Resistance exercise and mixed exercise (resistance and aerobic) work better than aerobic exercise alone (SOR: B, meta-analysis). High-frequency exercise is more effective than low-frequency exercise (SOR: B, small RCT). "Mindful" exercise, which has a meditative focus, such as tai chi and yoga, also reduces symptoms of depression (SO...

Sleep and Bipolar Episodes - A Vicious Circle

About.com Bipolar Disorder — Sat, 28 Aug 2010 23:00:00 +0100

Scientists are exploring the link between "clock" genes and bipolar disorder. For example, 2008 study found that a mutation in the core clock gene in mice produced hyperactivity and mania-like behavior. And as I wrote in Mood Disorders and Sleep, a short night can actually cause manic or hypomanic episodes. There's a lot of variance. I find that insomnia has a depressive effect on my mood, while hypersomnia (sleeping too much) is a symptom of my depression. Yet when I am hypomanic, I do have a decreased need for sleep. I am at my best when I consistently get 8 or 9 hours of restful sleep - or is it that I get 8 or 9 hours of sleep when I'm at my best? Some tricyclic antidepressants such as Elavil (amitriptyline) are known to have a beneficial effect on sleep, but the side effects, partic...

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Light treatment clears psoriasis as it boosts vitamin D levels

NaturalNews.com — Fri, 20 Aug 2010 07:00:00 +0100

(NaturalNews) According to the National Institutes of Health (NIH) about 7.5 million Americans suffer from the chronic, autoimmune skin disease called psoriasis that causes irritated, flaky and thick patches of red skin; some forms of psoriasis are also associated with joint pain. Most medical treatment for the often painful and quality-of-life robbing disease center around controlling symptoms with medications like cortisone. But now research just published in the August issue of the Archives of Dermatology indicates there's a non-drug way to clear and maybe cure the disease naturally -- exposure to vitamin D boosting UV-B light.Comprising the "tanning rays" from the sun that are blocked by sunscreen and long feared for supposedly causing wrinkles and "age spots", UV-B light, it turns out...

'Happy chair' to beat winter blues

Scotsman.com News - Health — Thu, 19 Aug 2010 23:37:14 +0100

A SPECIAL "happy chair" created to give much-needed light therapy to people suffering the winter blues has been designed by a student in Scotland. (Source: Scotsman.com News - Health)

Vitamin D not behind UVB's psoriasis benefit

Reuters: Health — Tue, 17 Aug 2010 18:20:23 +0100

NEW YORK (Reuters Health) - Ultraviolet light therapy lessens the symptoms of psoriasis and simultaneously raises vitamin D levels, a new study shows. However, increased vitamin D is probably unrelated to light therapy's benefits for psoriasis, the researchers say. (Source: Reuters: Health)

Vitamin D Not Behind UVB's Psoriasis Benefit

MedlinePlus Health News — Tue, 17 Aug 2010 17:20:23 +0100

Ultraviolet light therapy lessens the symptoms of psoriasis and simultaneously raises vitamin D levels, a new study shows. However, increased vitamin D is probably unrelated to light therapy's benefits for psoriasis, the researchers say.Source: Reuters Health Related MedlinePlus Pages: Psoriasis, Vitamin D (Source: MedlinePlus Health News)

Treating Acne Vulgaris: Systemic, Local and Combination Therapy

Medscape Today Headlines — Tue, 17 Aug 2010 10:36:36 +0100

Is light therapy the future of acne management? Expert Review of Clinical Pharmacology (Source: Medscape Today Headlines)

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Multi-centre imaging project aims at better diagnosis of brain conditions

OnMedica Latest News — Mon, 02 Aug 2010 23:00:00 +0100

Researchers say innovation vital to combat diseases of an ageing populationRelated items from OnMedicaCelebrities back brain donation campaignTwo new gene discoveries offer Alzheimer's hopeAlcohol 'reduces Alzheimer's risk'Old people unable to access mental health services Light therapy may help dementia patients (Source: OnMedica Latest News)

Circadian Rhythm Phase Advance with Dawn Simulation Treatment for Winter Depression

Journal of Biological Rhythms — Mon, 02 Aug 2010 16:29:38 +0100

A naturalistic pattern of dawn simulation (93 min, 0.001-250 lux) delivered to sleeping patients with winter depression has clinical efficacy similar to postawakening bright light therapy. The authors tested the circadian phase-shifting capacity of the dawn signal in a placebo-controlled, randomized 3-week field trial using 4 photic or nonphotic comparators: 30-min, 10,000-lux bright light therapy; a 13-min, 250-lux light pulse at the end of sleep; and high- and low-density negative air ionization timed to match the dawn. Bright light and dawn treatments both produced average phase advances of ~30 min, while the pulse and ion exposure had minimal effect. The authors conclude that very dim, incremental levels of light at the end of the night, with a dominant red component through eyelid fil...

A Clinician's Guide to Using Light Therapy [Reviews]

Psychiatric Bulletin — Mon, 02 Aug 2010 09:00:52 +0100

(Source: Psychiatric Bulletin)

Laser, light therapy may help treat stubborn nail disorders

Modern Medicine — Sat, 31 Jul 2010 23:00:00 +0100

Nail diseases are an important component of any dermatologist's practice. In many cases, treatment of nail conditions is difficult, as penetration of topical medications through the nail plate is challenging. Light therapy, which is able to travel through tissues and focus on specific targets without damage to surrounding normal skin or nail, would be a welcome option in the therapy of any nail disorder. (Source: Modern Medicine)

Introduction to experimental and clinical studies using low‐level Laser (light) therapy (LLLT)

Lasers in Surgery and Medicine — Sat, 31 Jul 2010 23:00:00 +0100

(Source: Lasers in Surgery and Medicine)

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Effect of pulsing in low‐level light therapy

Lasers in Surgery and Medicine — Sat, 31 Jul 2010 23:00:00 +0100

Abstract (Source: Lasers in Surgery and Medicine)

Prophylactic low‐level light therapy for the treatment of hypertrophic scars and keloids: A case series

Lasers in Surgery and Medicine — Sat, 31 Jul 2010 23:00:00 +0100

Abstract (Source: Lasers in Surgery and Medicine)

Effect of pulsing in low-level light therapy

Lasers in Surgery and Medicine — Mon, 19 Jul 2010 23:00:00 +0100

Low level light (or laser) therapy (LLLT) is a rapidly growing modality used in physical therapy, chiropractic, sports medicine and increasingly in mainstream medicine. LLLT is used to increase wound healing and tissue regeneration, to relieve pain and inflammation, to prevent tissue death, to mitigate degeneration in many neurological indications. While some agreement has emerged on the best wavelengths of light and a range of acceptable dosages to be used (irradiance and fluence), there is no agreement on whether continuous wave or pulsed light is best and on what factors govern the pulse parameters to be chosen.The published peer-reviewed literature was reviewed between 1970 and 2010.The basic molecular and cellular mechanisms of LLLT are discussed. The type of pulsed light sources avai...

Varying ratios of wavelengths in dual wavelength LED photomodulation alters gene expression profiles in human skin fibroblasts

Lasers in Surgery and Medicine — Mon, 19 Jul 2010 23:00:00 +0100

LED photomodulation has been shown to profoundly influence cellular behavior. A variety of parameters with LED photomodulation can alter cellular response in vitro. The effects of one visible and one infrared wavelength were evaluated to determine the optimal ratio to produce a net increase in dermal collagen by altering the ratio of total energy output of each wavelength. The ratio between the two wavelengths (590 and 870 nm) was shifted in 25% increments.Human skin fibroblasts in culture were exposed to a 590/870 nm LED array with total combined energy density fixed at 4.0 mW/cm.. The ratio of 590/870 nm tested parameters were: 100/0%, 75/25%, 50/50%, 25/75%, and 0/100%. These ratios were delivered using pulsed duty cycle of exposure (250 milliseconds "on" time/100 milliseconds "off" tim...

Prophylactic low-level light therapy for the treatment of hypertrophic scars and keloids: A case series

Lasers in Surgery and Medicine — Mon, 19 Jul 2010 23:00:00 +0100

Hypertrophic and keloid scars result from alterations in the wound healing process. Treating abnormal scars remains an important challenge. The aim of this case series was to investigate the effectiveness of near infrared (NIR) light emitting diode (LED) treatment as a prophylactic method to alter the wound healing process in order to avoid or attenuate the formation of hypertrophic scars or keloids.Three patients (age 27-57) of phototypes I-III with hypertrophic scars or keloids due to acne or surgery participated in this case series. Following scar revision by surgery or CO2 laser ablation on bilateral areas, one scar was treated daily by the patient at home with non-thermal, non-ablative NIR LED (805 nm at 30 mW/cm2) for 30 days. Efficacy assessments, conducted up to a year post-treatme...

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Ocular Complication of Intense Pulsed Light Therapy: Iris Photoablation

Dermatologic Surgery — Wed, 14 Jul 2010 23:00:00 +0100

The authors have indicated no significant interest with commercial supporters. (Source: Dermatologic Surgery)

Praying for Rain, Thanks to Summer Seasonal Affect Disorder

Psychology Today Anxiety Center — Thu, 08 Jul 2010 17:13:01 +0100

Today my home in the San Francisco Bay Area is completely socked in by thick fog. Seriously, I can't even see the house across the street. July 4 was a total washout: As usual, we couldn't see the fireworks over the bay, and just heard dim thumps through the chilly fog. I just received a voicemail message (because I'm not big on actually answering my phone) from someone who lives a mile away."It's freezing. Summers in this town are horrible," she said.They are -- if you actually crave sunshine.Which I do, but apparently there is a form of Seasonal Affect Disorder whose sufferers hate sunshine and strive to avoid it. Bright summer days without a cloud in the sky depress these folks. A story from Seattle's KIRO radio today looks into this small subset of a syndrome much better known for maki...

Introduction to experimental and clinical studies using low-level Laser (light) therapy (LLLT)

Lasers in Surgery and Medicine — Wed, 30 Jun 2010 23:00:00 +0100

No Abstract. (Source: Lasers in Surgery and Medicine)

Laser, light therapy useful in combating signs of sun exposure on chest, neck

Modern Medicine — Wed, 30 Jun 2010 05:55:40 +0100

Photoaging of the neck and chest is a common concern among patients. One of the most frequent clinical presentations is poikiloderma of Civatte (PC). First described by French dermatologist Achille Civatte in 1923, it is characterized by brown to pink patches of superficial atrophy, telangiectasia and mottled hyper- and hypopigmentation. (Source: Modern Medicine)

The Intensity and Duration of Exposure to Light Can Affect the Circadian Rhythm

NCCAM Featured Content — Mon, 21 Jun 2010 14:49:51 +0100

Circadian rhythms are the physical, mental, and behavioral changes that occur over the course of a day, responding primarily to light and darkness in the environment. Special non-image forming cells in the eye's retina that contain melanopsin (a pigment involved in the regulation of nonvisual responses) and are sensitive to blue light are known to affect these daily rhythms. These nonvisual responses also have been noted with higher intensity light levels. Now, new research reveals that green light and the cones and rods in the retina used for vision are also involved. The research, published in Science Translational Medicine, examined how melatonin (a major hormone associated with human sleeping patterns) responds to different wavelengths of light and suggests that light therapy for sleep...

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Bright light therapy improves sleep disturbances in soldiers with combat PTSD, research finds

ScienceDaily Headlines — Tue, 15 Jun 2010 14:53:53 +0100

Bright light therapy has significant effects on sleep disturbances associated with combat-related post-traumatic stress disorder, according to new research. (Source: ScienceDaily Headlines)

Light therapy by blue LED improves wound healing in an excision model in rats

Injury — Tue, 15 Jun 2010 14:00:11 +0100

Conclusion: In contrast to previous studies, we showed that also blue light significantly influences wound healing. Furthermore, our data suggest that light therapy can play an important role in normotrophic wound healing by affecting keratin expression. Illumination would provide an easily applicable, safe and cost-effective treatment of surface wounds. (Source: Injury)

Bright Light Therapy Improves Sleep in PTSD

Medscape Medical News Headlines — Thu, 10 Jun 2010 16:00:55 +0100

Bright light therapy helps relieve sleep disturbances in soldiers with posttraumatic stress disorder (PTSD), according to preliminary findings reported this week in San Antonio at the 24th annual meeting of the Associated Professional Sleep Societies LLC. Reuters Health Information (Source: Medscape Medical News Headlines)

Bright Light Helps Soldiers Sleep

Medical Headlines From Ivanhoe.com — Tue, 08 Jun 2010 05:00:00 +0100

(Ivanhoe Newswire) -- Bright light therapy has demonstrated beneficial effects on sleep disturbances associated with combat-related post-traumatic stress disorder (PTSD), and it also produced a moderate improvement in PTSD symptoms and depression. (Source: Medical Headlines From Ivanhoe.com)

Sleep Disturbances In Soldiers With Combat PTSD Improved By Bright Light Therapy

Health News from Medical News Today — Mon, 07 Jun 2010 09:00:00 +0100

Bright light therapy has significant effects on sleep disturbances associated with combat-related post-traumatic stress disorder, according to a research abstract that will be presented Monday, June 7, 2010, in San Antonio, Texas, at SLEEP 2010, the 24th annual meeting of the Associated Professional Sleep Societies LLC. Results indicate that bright light therapy produced a significantly greater improvement than placebo in sleep disturbances specific to PTSD. Bright light therapy also produced a moderate improvement in PTSD symptoms and depression... (Source: Health News from Medical News Today)

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Bright light therapy improves sleep disturbances in soldiers with combat PTSD

EurekAlert! - Social and Behavioral Science — Mon, 07 Jun 2010 04:00:00 +0100

(American Academy of Sleep Medicine) Bright light therapy produced a significantly greater improvement than placebo in sleep disturbances specific to PTSD. Bright light therapy also produced a moderate improvement in PTSD symptoms and depression. The study involved 16 soldiers with combat-related PTSD who served in Operation Enduring Freedom or Operation Iraqi Freedom. Eight soldiers received 10,000 lux of bright light therapy for 30 minutes each day, and eight participants received sham treatment with an inactivated negative ion generator. (Source: EurekAlert! - Social and Behavioral Science)

Rosacea treatment: Can light therapy reduce symptoms?

MayoClinic.com - Ask a Specialist — Fri, 28 May 2010 01:45:04 +0100

Rosacea treatment — Light therapy may be helpful for some people. (Source: MayoClinic.com - Ask a Specialist)

Accidental cure ends 50 years of psoriasis

Telegraph Health — Fri, 14 May 2010 18:47:37 +0100

Doctor's Diary: How an 'accident' can reveal the definitive remedy for an ailment and walnuts can lower cholestrol. (Source: Telegraph Health)

Infrared radiation has potential antidepressant and anxiolytic effects in animal model of depression and anxiety

Sun, 09 May 2010 23:00:00 +0100

Conclusions: These results indicate that chronic infrared radiation might produce antidepressant- and anxiolytic-like effects. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)

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Circadian rhythms and depression.

Australian Family Physician — Fri, 30 Apr 2010 23:00:00 +0100

This article discusses circadian rhythms and the disruption to them associated with depression, and reviews nonpharmaceutical and pharmaceutical interventions to shift circadian rhythms. DISCUSSION: Features of depression suggestive of a disturbance to circadian rhythms include early morning waking, diurnal mood changes, changes in sleep architecture, changes in timing of the temperature nadir, and peak cortisol levels. Interpersonal social rhythm therapy involves learning to manage interpersonal relationships more effectively and stabilisation of social cues, such as including sleep and wake times, meal times, and timing of social contact. Bright light therapy is used to treat seasonal affective disorders. Agomelatine is an antidepressant that works in a novel way by targeting melatonergi...

Adenovirus-mediated LIGHT gene modification in murine B-cell lymphoma elicits a potent antitumor effect.

Cellular and Molecular Immunology — Sun, 25 Apr 2010 23:00:00 +0100

Authors: Hu G, Liu Y, Li H, Zhao D, Yang L, Shen J, Hong X, Cao X, Wang Q Here, we investigated the antitumor effect of adenovirus-mediated gene transfer of LIGHT, the tumor-necrosis factor (TNF) superfamily member also known as TNFSF14, in the murine A20 B-cell lymphoma. LIGHT gene modification resulted in upregulated expression of Fas and the accessory molecule-intercellular adhesion molecule-1 (ICAM-1) on A20 cells and led to enhanced A20 cell apoptosis. LIGHT-modified A20 cells effectively stimulated the proliferation of T lymphocytes and interferon (IFN)-gamma production in vitro. Immunization of BALB/c mice with a LIGHT-modified A20 cell vaccine efficiently elicited protective immunity against challenge with the parental tumor cell line. Adenovirus-mediated gene transfer of LIGHT...

Complementary and Alternative Medicine for the Treatment of Depressive Disorders in Women

The Psychiatric Clinics of North America — Mon, 12 Apr 2010 16:06:23 +0100

This article reviews several CAM treatments for depressive disorders in women, with a focus on major depressive disorder across the reproductive life cycle. The CAM therapies selected for this review (ie, S-adenosylmethionine, omega-3 fatty acids, St John's wort, bright light therapy, acupuncture, and exercise) were based on their prevalence of use and the availability of randomized, placebo-controlled data. Further study is necessary to delineate the role of specific CAM therapies in premenstrual syndrome, premenstrual dysphoric disorder, antepartum and postpartum depression, lactation, and the menopausal transition. (Source: The Psychiatric Clinics of North America)

Alaska Northern Lights Offers Bright Light Therapy To Combat Common Health Problems

Health News from Medical News Today — Thu, 01 Apr 2010 00:00:00 +0100

Alaska Northern Lights manufactures a bright light therapy box that aids in treating chronic health problems such as seasonal affective disorder (SAD), depression, bipolar disorder and sleep problems. Sufferers of SAD, a form of clinical depression, include up to 25 percent of those living in northern latitudes who experience varying degrees of SAD during winter months when there is less natural light. Night shift workers are also susceptible to SAD which affects over one third of the population, or about 10.8 million Americans... (Source: Health News from Medical News Today)

Spring Forward, Fall Back Into Depression?

About.com Depression — Mon, 15 Mar 2010 05:42:01 +0100

While many look forward to Daylight Saving Time and having more light at the end of the day, others, especially those with seasonal affective disorder (SAD), may find themselves slipping back into depression at this time of year. SAD, according to experts, is caused by a disturbance in our circadian rhythm. Light entering into the eye controls this rhythm; but, during the winter months when days are shorter we may not be exposed to sufficient light during the morning hours, throwing our circadian rhythm off-balance and creating the symptoms of SAD (depression, fatigue and a craving for sweets). For those with SAD, the longer days of spring bring relief from depression. The arrival of Daylight Saving Time, however, may cause a temporary return of these symptoms as you are forced to once...

Health news: Potato juice cures indigestion and how light therapy helps skin conditions

the Mail online | Health — Tue, 09 Mar 2010 09:10:22 +0100

Health stories from around the world this week include a new study which found drinking potato juice daily can help indigestion. (Source: the Mail online | Health)

Seasonal affective disorder increasingly a workplace issue

Los Angeles Times - Science — Thu, 04 Mar 2010 01:20:00 +0100

Some employees seek adjustments for SAD, serious depression triggered by limited daylight. One teacher sued a school district that refused to move her from a windowless basement room. Since she was hired two years ago as a medical assistant, Jennifer Simonsis has come to an agreement with her employer: During the winter, she gets time off to see her doctor, frequent breaks and help in setting up a light-therapy lamp at her desk. (Source: Los Angeles Times - Science)

Peginterferon--2b: Exacerbation of psoriasis, treated with UVB light therapy: case report

Reactions — Mon, 01 Mar 2010 14:50:10 +0100

(Source: Reactions)

Quiz Page March 2010: Pruritus in Advanced CKD

American Journal of Kidney Diseases — Fri, 26 Feb 2010 15:56:18 +0100

A 55-year-old man with a history of hypertension, type 2 diabetes, and advanced chronic kidney disease (CKD) presented with generalized pruritus for > 6 months. The patient had no history of allergic or atopic disease. Physical examination showed generalized xerosis and hyperpigmentation of the trunk (). No papules, pustules, or vesicles were noted, but hyperkeratosis and heavy crusting were present on both palms (). Routine blood tests showed the following values: urea nitrogen, 49 mg/dL (17.4 mmol/L); serum creatinine, 5.3 mg/dL (468.5 μmol/L, estimated glomerular filtration rate, 12.5 mL/min/1.73 m2 [0.21 mL/s/1.73 m2]); calcium, 9.2 mg/dL (2.3 mmol/L); phosphate, 5.2 mg/dL (1.6 mmol/L); and hemoglobin, 6.4 g/dL (64 g/L). Despite treatment with topical emollients, oral antihistamine, a...

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Prevention of depression and sleep disturbances in elderly with memory-problems by activation of the biological clock with light - a randomized clinical trial

Trials — Tue, 23 Feb 2010 00:00:00 +0100

This study investigates whether long-term daily bright light prevents worsening of sleep-wake rhythms and depressive symptoms in elderly people with memory complaints. Patients with early Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) and Subjective Memory Complaints (SMC), between the ages of 50 and 75, are included in a randomized double-blind placebo-controlled trial. For the duration of two years, patients are exposed to ~10,000 lux in the active condition or ~300 lux in the placebo condition, daily, for two half-hour sessions at fixed times in the morning and evening. Neuropsychological, behavioral, physiological and endocrine measures are assessed at baseline and follow-up every five to six months.DiscussionIf bright light therapy attenuates the worsening of sleep-wake rhy...

Can You Treat Acne With an iPhone App?

WebMD Health — Fri, 12 Feb 2010 20:24:29 +0100

Some dermatologists are skeptical about the effectiveness of an iPhone app that promises to treat acne with light therapy. (Source: WebMD Health)

Impact of ambient bright light on agitation in dementia

International Journal of Geriatric Psychiatry — Wed, 27 Jan 2010 00:00:00 +0100

To evaluate the effect of ambient bright light therapy (BLT) on agitation among institutionalized persons with dementia.High intensity, low glare ambient lighting was installed in activity and dining areas of a state psychiatric hospital unit in North Carolina and a dementia-specific residential care facility in Oregon. The study employed a cluster-unit crossover design involving four ambient lighting conditions: AM bright light, PM bright light, All Day bright light, and Standard light. Sixty-six older persons with dementia participated. Outcome measures included direct observation by research personnel and completion by staff caregivers of the 14-item, short form of the Cohen-Mansfield Agitation Inventory (CMAI).Analyses of observational data revealed that for participants with mild/mode...

New Dementia Tzar appointed by Department of Health

OnMedica Latest News — Mon, 25 Jan 2010 00:00:00 +0100

New dementia director will oversee national dementia strategyRelated items from OnMedicaGovernment failing on dementia care Plans launched to curb over-use of antipsychoticsMajority of people fear 'getting old'Light therapy may help dementia patientsElderly patients often receive undignified care (Source: OnMedica Latest News)