This is a selection of articles from the March 2007 archive. Click here for this month's Biomedical Science headlines.
Strategy for selecting and characterizing linker peptides for CBM9-tagged fusion proteins expressed in E. coli
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Source: Biotechnology and Bioengineering - March 29, 2007 Authors: Mojgan Kavoosi, A. Louise Creagh, Douglas G. Kilburn, Charles A. Haynes Source Type: news
Online medium-throughput respirometry-based OTR measurements in magnetically stirred cultures
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Source: Biotechnology and Bioengineering - March 28, 2007 Authors: Simone Brethauer, Martin Held, Sven Panke Source Type: news
The tip of the iceberg
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Source: Biotechnology and Bioengineering - March 27, 2007 Source Type: news
Factoring in apoptosis inhibition in rFVIII production
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Source: Biotechnology and Bioengineering - March 27, 2007 Source Type: news
Control of hepatic differentiation via cellular aggregation in an alginate microenvironment
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Source: Biotechnology and Bioengineering - March 27, 2007 Authors: Tim Maguire, Alexander E. Davidovich, Eric J. Wallenstein, Eric Novik, Nripen Sharma, Henrik Pedersen, Ioannis P. Androulakis, Rene Schloss, Martin Yarmush Source Type: news
The investigator with two watches: Incongruities observed in 'omics' approaches
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Source: Biotechnology and Bioengineering - March 27, 2007 Source Type: news
Peptides derived from a secretory yeast library restore factor VIII activity in the presence of an inhibitory antibody
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Source: Biotechnology and Bioengineering - March 27, 2007 Authors: Christa Mersich, Werner Billes, Ingrid Pabinger, Alois Jungbauer Source Type: news
Simplified inclusion body processing
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Source: Biotechnology and Bioengineering - March 27, 2007 Source Type: news
Microbial production of hydrogen and ethanol from glycerol-containing wastes discharged from a biodiesel fuel production plant in a bioelectrochemical reactor with thionine
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Source: Biotechnology and Bioengineering - March 27, 2007 Authors: Shinsuke Sakai, Tatsuo Yagishita Source Type: news
Process development for the electroenzymatic synthesis of (R)-methylphenylsulfoxide by use of a 3-dimensional electrode
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Source: Biotechnology and Bioengineering - March 27, 2007 Authors: S. Lütz, K. Vuorilehto, A. Liese Source Type: news
A scaffold for the Chinese hamster genome
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Source: Biotechnology and Bioengineering - March 27, 2007 Authors: Katie F. Wlaschin, Wei-Shou Hu Source Type: news
Tissue engineering with electric fields: immobilisation of mammalian cells in multilayer aggregates using dielectrophoresis
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Anil Sebastian, Anne-Marie Buckle, Gerard H. Markx Source Type: news
Optimization of fed-batch parameters and harvest time of CHO cell cultures for a glycosylated product with multiple mechanisms of inactivation
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Ryan S. Senger, M. Nazmul Karim Source Type: news
Significance analysis of time-series transcriptomic data: A methodology that enables the identification and further exploration of the differentially expressed genes at each time-point
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Bhaskar Dutta, Robert Snyder, Maria I. Klapa Source Type: news
Fibronectin and culture temperature modulate the efficacy of an avidin-biotin binding system for chondrocyte adhesion and growth on biodegradable polymers
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Wei-Bor Tsai, Peng-Yuan Wang, Yung Chang, Min-Cheng Wang Source Type: news
Acid-catalyzed steam pretreatment of Lodgepole pine and subsequent enzymatic hydrolysis and fermentation to ethanol
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Shannon M. Ewanick, Renata Bura, John N. Saddler Source Type: news
A scaleable manufacturing process for pro-EP-B2, a cysteine protease from barley indicated for celiac sprue
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Harmit Vora, James McIntire, Pawan Kumar, Milind Deshpande, Chaitan Khosla Source Type: news
Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models
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Source: Theoretical Biology and Medical Modelling - March 26, 2007 Authors: Michaela Vossen, Michael Sevestre, Christoph Niederalt, In-Jin Jang, Stefan Willmann and Andrea N Edginton Source Type: news
Analysis of lipid hydrolytic activity by esterase on blotting membrane followed by separation using non-denaturing two-dimensional gel electrophoresis
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Youji Shimazaki, Masayuki Miyamoto Source Type: news
Effluent recirculation to improve perchlorate reduction in a fixed biofilm reactor
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Hyeoksun Choi, JoAnn Silverstein Source Type: news
Enzyme-linked immunosorbent assay of Escherichia coli O157:H7 in surface enhanced poly(methyl methacrylate) microchannels
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Source: Biotechnology and Bioengineering - March 26, 2007 Authors: Yunling Bai, Wei-Cho Huang, Shang-Tian Yang Source Type: news
Aligned Silver Nanoparticles on Rippled Silicon Templates Exhibiting Anisotropic Plasmon Absorption
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Source: Plasmonics - March 11, 2007 Tags: Plasmonics Source Type: news
Combined removal of sulfur compounds and nitrate by autotrophic denitrification in bioaugmented activated sludge system
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Source: Biotechnology and Bioengineering - March 10, 2007 Authors: I. Manconi, A. Carucci, P. Lens Source Type: news
Binding and enrichment of Escherichia coli spheroplasts expressing inner membrane tethered scFv antibodies on surface immobilized antigens
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Sang Taek Jung, Ki Jun Jeong, Brent L. Iverson, George Georgiou Source Type: news
Monitoring denitrification by pH-stat titration
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Elena Ficara, Roberto Canziani Source Type: news
Asymmetric alkene reduction by yeast Old Yellow Enzymes and by a novel Zymomonas mobilis reductase
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: André Müller, Bernhard Hauer, Bettina Rosche Source Type: news
An annotated bibliography of C.J. van der Klaauw with notes on the impact of his work.
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Source: Acta Biotheoretica - March 9, 2007 Authors: Dubbeldam JL Tags: Acta Biotheor Source Type: news
Selection and initial characterization of novel peptide ligands that bind specfically to human blood outgrowth endothelial cells
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Anka N. Veleva, Stuart L. Cooper, Cam Patterson Source Type: news
Kinetics of in vivo bone deposition by bone marrow stromal cells within a resorbable porous calcium phosphate scaffold: a X-ray computed microtomography study
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Papadimitropoulos A, Mastrogiacomo M, Peyrin F, Molinari E, Komlev VS, Rustichelli F, Cancedda R Source Type: news
Monitoring of dissolved oxygen and cellular bioenergetics within a pancreatic substitute
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Jeffrey D. Gross, R.C. Long Jr., I. Constantinidis, A. Sambanis Source Type: news
Natural Genome-Editing Competences of Viruses.
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Source: Acta Biotheoretica - March 9, 2007 Authors: Witzany G Tags: Acta Biotheor Source Type: news
Fed-batch bioreactor process scale-up from 3-L to 2500-L scale for monoclonal antibody production from cell culture
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Jeng-Dar Yang, Canghai Lu, Brad Stasny, Joseph Henley, Woodrow Guinto, Carlos Gonzalez, Joseph Gleason, Monica Fung, Brett Collopy, Michael Benjamino, Jennifer Gangi, Melissa Hanson, Elisabeth Ille Source Type: news
Validation of a two-parameter quantitative structure activity relationship as a legitimate tool for rational re-design of horseradish peroxidase
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Lisa M. Colosi, Qingguo Huang, Walter J. Weber Jr. Source Type: news
Optimal design of metabolic flux analysis experiments for anchorage-dependent mammalian cells using a cellular automaton model
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Adam L. Meadows, Siddhartha Roy, Douglas S. Clark, Harvey W. Blanch Source Type: news
Influence of the pH on (open) mixed culture fermentation of glucose, a chemostat study
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Margarida F Temudo, Robbert Kleerebezem, Mark van Loosdrecht Source Type: news
The lipase-catalyzed hydrolysis of lutein diesters in non-aqueous media is favored at extremely low water
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: J. Mauricio Mora-Pale, Sandra Pérez- Munguía, Jessica C. González- Mejía, Jonathan S. Dordick, Eduardo Bárzana Source Type: news
Design and application of an oscillatory compression device for cell constructs
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Source: Biotechnology and Bioengineering - March 9, 2007 Authors: Theresa R. Cassino, Roger Anderson, Brian J. Love, William R. Huckle, Diane K. Seamans, Kimberly Forsten-Williams Source Type: news
Asymmetric Karplus curves for the protein side-chain (3) J couplings.
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Source: Journal of Bimolecular NMR - March 7, 2007 Authors: Schmidt JM Tags: J Biomol NMR Source Type: news
Rapid and accurate processing method for amide proton exchange rate measurement in proteins.
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Source: Journal of Bimolecular NMR - March 7, 2007 Authors: Koskela H, Heikkinen O, Kilpeläinen I, Heikkinen S Tags: J Biomol NMR Source Type: news
NMR solution structure of the reduced form of thioredoxin 2 from Saccharomyces cerevisiae.
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Source: Journal of Bimolecular NMR - March 6, 2007 Authors: Amorim GC, Pinheiro AS, Netto LE, Valente AP, Almeida FC Tags: J Biomol NMR Source Type: news
Specific volume and adiabiatic compressibility measurements of native and aggregated recombinant human interleukin 1-receptor antagonist: Density differences enable pressure-modulated refolding
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Source: Biotechnology and Bioengineering - March 4, 2007 Authors: Matthew B. Seefeldt, Chris Crouch, Brent Kendrick, Theodore W. Randolph Source Type: news
High-yields and extended serum half-life of human interferon [alpha]2b expressed in tobacco cells as arabinogalactan-protein fusions
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Source: Biotechnology and Bioengineering - March 3, 2007 Authors: Jianfeng Xu, Li Tan, Kenneth J. Goodrum, Marcia J. Kieliszewski Source Type: news
Strong coupling effects during X-pulse CPMG experiments recorded on heteronuclear ABX spin systems: artifacts and a simple solution.
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Source: Journal of Bimolecular NMR - March 3, 2007 Authors: Vallurupalli P, Scott L, Williamson JR, Kay LE Tags: J Biomol NMR Source Type: news
All-atom molecular dynamics simulations using orientational constraints from anisotropic NMR samples.
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Source: Journal of Bimolecular NMR - March 3, 2007 Authors: Sternberg U, Witter R, Ulrich AS Tags: J Biomol NMR Source Type: news
Influence of Silver Colloid Presence on Stilbazolium Merocyanine Emission
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Source: Plasmonics - March 2, 2007 Tags: Plasmonics Source Type: news
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Vaisar, T., Pennathur, S., Green, P. S., Gharib, S. A., Hoofnagle, A. N., Cheung, M. C., Byun, J., Vuletic, S., Kassim, S., Singh, P., Chea, H., Knopp, R. H., Brunzell, J., Geary, R., Chait, A., Zhao, X.-Q., Elkon, K., Marcovina, S., Ridker, P., Oram, J. Tags: Research Article Source Type: news
Role of a CUF1/CTR4 copper regulatory axis in the virulence of Cryptococcus neoformans
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Waterman, S. R., Hacham, M., Hu, G., Zhu, X., Park, Y.-D., Shin, S., Panepinto, J., Valyi-Nagy, T., Beam, C., Husain, S., Singh, N., Williamson, P. R. Tags: Research Article Source Type: news
Prenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disorders
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Mollet, J., Giurgea, I., Schlemmer, D., Dallner, G., Chretien, D., Delahodde, A., Bacq, D., de Lonlay, P., Munnich, A., Rotig, A. Tags: Research Article Source Type: news
A new JCI conflict-of-interest policy
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Neill, U. S., Thompson, C. B., Feldmann, M., Kelley, W. N. Tags: Editorial Source Type: news
The role of CXC chemokines in pulmonary fibrosis
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Strieter, R. M., Gomperts, B. N., Keane, M. P. Tags: Review Series Source Type: news
Francis Crick: Discoverer of the genetic code
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Stevens, C. Tags: Book Review Source Type: news
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Iredale, J. P. Tags: Review Series Source Type: news
Salt, sodium channels, and SGK1
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Pearce, D., Kleyman, T. R. Tags: Commentary Source Type: news
The fundamental basis of inflammatory bowel disease
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Strober, W., Fuss, I., Mannon, P. Tags: Science in Medicine Source Type: news
Immunopathogenesis and therapy of cutaneous T cell lymphoma
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Kim, E. J., Hess, S., Richardson, S. K., Newton, S., Showe, L. C., Benoit, B. M., Ubriani, R., Vittorio, C. C., Junkins-Hopkins, J. M., Wysocka, M., Rook, A. H. Tags: Corrigendum Source Type: news
Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Dahl, M., Bauer, A. K., Arredouani, M., Soininen, R., Tryggvason, K., Kleeberger, S. R., Kobzik, L. Tags: Research Article Source Type: news
High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Pierantoni, G. M., Rinaldo, C., Mottolese, M., Di Benedetto, A., Esposito, F., Soddu, S., Fusco, A. Tags: Research Article Source Type: news
The devil's doctor: Paracelsus and the world of Renaissance magic and science
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: FitzGerald, G. Tags: Book Review Source Type: news
Systemic sclerosis: a prototypic multisystem fibrotic disorder
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Varga, J., Abraham, D. Tags: Review Series Source Type: news
Trichostatin A increases SMN expression and survival in a mouse model of spinal muscular atrophy
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Avila, A. M., Burnett, B. G., Taye, A. A., Gabanella, F., Knight, M. A., Hartenstein, P., Cizman, Z., Di Prospero, N. A., Pellizzoni, L., Fischbeck, K. H., Sumner, C. J. Tags: Research Article Source Type: news
Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Meyer-Lindenberg, A., Straub, R. E., Lipska, B. K., Verchinski, B. A., Goldberg, T., Callicott, J. H., Egan, M. F., Huffaker, S. S., Mattay, V. S., Kolachana, B., Kleinman, J. E., Weinberger, D. R. Tags: Research Article Source Type: news
Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Khoury, J., Ibla, J. C., Neish, A. S., Colgan, S. P. Tags: Research Article Source Type: news
Scavenger receptors clear the air
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Postlethwait, E. M. Tags: Commentary Source Type: news
Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Grammer, A. C., Slota, R., Fischer, R., Gur, H., Girschick, H., Yarboro, C., Illei, G. G., Lipsky, P. E. Tags: Corrigendum Source Type: news
In this issue
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Source: Journal of Clinical Investigation - March 1, 2007 Tags: In This Issue Source Type: news
The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Dickey, C. A., Kamal, A., Lundgren, K., Klosak, N., Bailey, R. M., Dunmore, J., Ash, P., Shoraka, S., Zlatkovic, J., Eckman, C. B., Patterson, C., Dickson, D. W., Nahman, N. S., Hutton, M., Burrows, F., Petrucelli, L. Tags: Research Article Source Type: news
Impaired neutrophil activity and increased susceptibility to bacterial infection in mice lacking glucose-6-phosphatase-{beta}
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Cheung, Y. Y., Kim, S. Y., Yiu, W. H., Pan, C.-J., Jun, H.-S., Ruef, R. A., Lee, E. J., Westphal, H., Mansfield, B. C., Chou, J. Y. Tags: Research Article Source Type: news
Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Schauber, J., Dorschner, R. A., Coda, A. B., Buchau, A. S., Liu, P. T., Kiken, D., Helfrich, Y. R., Kang, S., Elalieh, H. Z., Steinmeyer, A., Zugel, U., Bikle, D. D., Modlin, R. L., Gallo, R. L. Tags: Research Article Source Type: news
Halfway there: the struggle to manage conflicts of interest
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Caplan, A. L. Tags: Personal Perspective Source Type: news
Evolution, not revolution
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Source: Journal of Clinical Investigation - March 1, 2007 Authors: Turka, L. A. Tags: Editorial Source Type: news