This is a selection of articles from the April 2007 archive. Click here for this month's Biomedical Science headlines.
A single-quantum methyl (13)C-relaxation dispersion experiment with improved sensitivity.
discuss this article
Source: Journal of Bimolecular NMR - April 27, 2007 Authors: Lundström P, Vallurupalli P, Religa TL, Dahlquist FW, Kay LE Tags: J Biomol NMR Source Type: info
Activity of human P450 2D6 in biphasic solvent systems
discuss this article
Source: Biotechnology and Bioengineering - April 27, 2007 Authors: Jin Zhao, Elaine Tan, Julian Ferras, Karine Auclair Source Type: info
Ozone Therapy in Induced Endotoxemic Shock. II. The Effect of Ozone Therapy Upon Selected Histochemical Reactions in Organs of Rats in Endotoxemic Shock
discuss this article
Source: Inflammation - April 26, 2007 Tags: Inflammation Source Type: info
InXy and SeXy, compact heterologous reporter proteins for mammalian cells
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: David A. Fluri, Jens M. Kelm, Guillaume Lesage, Marie Daoud-El Baba, Martin Fussenegger Source Type: info
A novel solid-liquid two-phase partitioning bioreactor for the enhanced bioproduction of 3-methylcatechol
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: George P. Prpich, Andrew J. Daugulis Source Type: info
Proteome analysis of antibody-producing CHO cell lines with different metabolic profiles
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: Deborah E. Pascoe, David Arnott, Eleftherios T. Papoutsakis, William M. Miller, Dana C. Andersen Source Type: info
Production of lentiviral vectors by large-scale transient transfection of suspension cultures and affinity chromatography purification
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: María Mercedes Segura, Alain Garnier, Yves Durocher, Helene Coelho, Amine Kamen Source Type: info
Influence of microbial growth kinetics on steady state multiplicity and stability of a two-step nitrification (SHARON) model
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: Eveline I.P. Volcke, Mihaela Sbarciog, Mia Loccufier, Peter A. Vanrolleghem, Erik J.L. Noldus Source Type: info
Elucidation of the mechanism and end products of glutaraldehyde crosslinking reaction by X-ray structure analysis
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: Yariv Wine, Noa Cohen-Hadar, Amihay Freeman, Felix Frolow Source Type: info
A systematic analysis of backbone amide assignments achieved via combinatorial selective labelling of amino acids.
discuss this article
Source: Journal of Bimolecular NMR - April 26, 2007 Authors: Jeremy Craven C, Al-Owais M, Parker MJ Tags: J Biomol NMR Source Type: info
Effect of moderate electric field on the metabolic activity and growth kinetics of Lactobacillus acidophilus
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: L. Loghavi, S.K. Sastry, A.E. Yousef Source Type: info
A genetic time-delay circuitry in mammalian cells
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: Wilfried Weber, Beat P. Kramer, Martin Fussenegger Source Type: info
Maximum entropy reconstruction of joint phi, psi-distribution with a coil-library prior: the backbone conformation of the peptide hormone motilin in aqueous solution from phi and psi-dependent J-couplings.
discuss this article
Source: Journal of Bimolecular NMR - April 26, 2007 Authors: Massad T, Jarvet J, Tanner R, Tomson K, Smirnova J, Palumaa P, Sugai M, Kohno T, Vanatalu K, Damberg P Tags: J Biomol NMR Source Type: info
Size comparison between proteins PEGylated with branched and linear poly(ethylene glycol) molecules
discuss this article
Source: Biotechnology and Bioengineering - April 26, 2007 Authors: Conan J. Fee Source Type: info
Computational methods in protein structure prediction
discuss this article
Source: Biotechnology and Bioengineering - April 23, 2007 Authors: C.A. Floudas Source Type: info
Viral technology enters a new phase
discuss this article
Source: Biotechnology and Bioengineering - April 23, 2007 Source Type: info
Why some grow less while eating more
discuss this article
Source: Biotechnology and Bioengineering - April 23, 2007 Source Type: info
Management of the mammalian cell factory
discuss this article
Source: Biotechnology and Bioengineering - April 23, 2007 Source Type: info
Cellulose pretreatment and hydrolysis: Plant cell wall deconstruction
discuss this article
Source: Biotechnology and Bioengineering - April 23, 2007 Source Type: info
Protein-protein interaction site mapping using NMR-detected mutational scanning.
discuss this article
Source: Journal of Bimolecular NMR - April 20, 2007 Authors: Baminger B, Ludwiczek ML, Kontaxis G, Knapp S, Konrat R Tags: J Biomol NMR Source Type: info
Editorial.
discuss this article
Source: Journal of Bimolecular NMR - April 14, 2007 Authors: Wüthrich K Tags: J Biomol NMR Source Type: info
The NMR structure of the domain II of a chloroplastic NifU-like protein OsNifU1A.
discuss this article
Source: Journal of Bimolecular NMR - April 13, 2007 Authors: Kumeta H, Ogura K, Asayama M, Katoh S, Katoh E, Teshima K, Inagaki F Tags: J Biomol NMR Source Type: info
Can visco-elastic phase separation, macromolecular crowding and colloidal physics explain nuclear organisation?
discuss this article
Source: Theoretical Biology and Medical Modelling - April 12, 2007 Authors: Francisco J Iborra Source Type: info
Introduction of David G. Nathan, MD: 2006 Association of American Physicians George M. Kober Medal
discuss this article
Source: Journal of Clinical Investigation - April 11, 2007 Authors: Benz, E. J. Tags: Supplement Source Type: info
A novel method of encapsulating and cultivating adherent mammalian cells within collagen microcarriers
discuss this article
Source: Biotechnology and Bioengineering - April 10, 2007 Authors: Ta-Jen Wu, Hsiu-Hsuan Huang, Yuan-Ming Hsu, Shaw-Ruey Lyu, Yng Jiin Wang Source Type: info
Optimal thermotolerance of bifidobacterium bifidum in gellan-alginate microparticles
discuss this article
Source: Biotechnology and Bioengineering - April 9, 2007 Authors: Ming-Ju Chen, Kun-Nan Chen, Yi-Tzu Kuo Source Type: info
On the use of the T-RExTM tetracycline-inducible gene expression system in vivo
discuss this article
Source: Biotechnology and Bioengineering - April 9, 2007 Authors: Vasily N Dobrovolsky, Robert H Heflich Source Type: info
Functional genome-wide analysis of antibody producing NS0 cell line cultivated at different temperatures
discuss this article
Source: Biotechnology and Bioengineering - April 9, 2007 Authors: Halina Swiderek, Mohamed Al-Rubeai Source Type: info
Effect of doxycycline-regulated protein disulfide isomerase expression on the specific productivity of recombinant CHO cells: thrombopoietin and antibody
discuss this article
Source: Biotechnology and Bioengineering - April 9, 2007 Authors: Chaya Mohan, Soon Hye Park, Joo Young Chung, Gyun Min Lee Source Type: info
Hydrogen sulphide production from elemental sulphur by Desulfovibrio desulphuricans in an anaerobic bioreactor
discuss this article
Source: Biotechnology and Bioengineering - April 9, 2007 Authors: Claudio Escobar, Loreto Bravo, José Hernández, Leandro Herrera Source Type: info
Tracer measurements reveal experimental evidence of biofilm consolidation
discuss this article
Source: Biotechnology and Bioengineering - April 9, 2007 Authors: Eoin Casey Source Type: info
Optimal fed batch cultivation when mass transfer becomes limiting
discuss this article
Source: Biotechnology and Bioengineering - April 9, 2007 Authors: John Villadsen, Kiran R. Patil Source Type: info
Structure and shear strength of microbial biofilms as determined with confocal laser scanning microscopy and fluid dynamic gauging using a novel rotating disc biofilm reactor
discuss this article
Source: Biotechnology and Bioengineering - April 9, 2007 Authors: Roland B. Möhle, Timo Langemann, Marian Haesner, Wolfgang Augustin, Stephan Scholl, Thomas R. Neu, Dietmar C. Hempel, Harald Horn Source Type: info
NMR assignment of the E. coli type 1 pilus protein FimF.
discuss this article
Source: Journal of Bimolecular NMR - April 7, 2007 Authors: Gossert AD, Hiller S, Fiorito F, Wüthrich K Tags: J Biomol NMR Source Type: info
(1)H, (13)C and (15)N resonance assignments of rabbit prion protein (91-228).
discuss this article
Source: Journal of Bimolecular NMR - April 6, 2007 Authors: Li J, Mei FH, Xiao GF, Guo CY, Lin DH Tags: J Biomol NMR Source Type: info
Assignment of (1)H, (13)C, and (15)N resonances for SF2 RNA recognition motif 2.
discuss this article
Source: Journal of Bimolecular NMR - April 6, 2007 Authors: Tintaru AM, Hautbergue GM, Hounslow AM, Lian LY, Wilson SA, Craven CJ Tags: J Biomol NMR Source Type: info
Silica-immobilized enzymes for multi-step synthesis in microfluidic devices
discuss this article
Source: Biotechnology and Bioengineering - April 5, 2007 Authors: Heather R. Luckarift, Bosung S. Ku, Jonathan S. Dordick, Jim C. Spain Source Type: info
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Bell, H. S., Dufes, C., O'Prey, J., Crighton, D., Bergamaschi, D., Lu, X., Schatzlein, A. G., Vousden, K. H., Ryan, K. M. Tags: Research Article Source Type: info
Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Tsou, C.-L., Peters, W., Si, Y., Slaymaker, S., Aslanian, A. M., Weisberg, S. P., Mack, M., Charo, I. F. Tags: Research Article Source Type: info
Acceptance of the 2006 Kober Medal: 2006 Association of American Physicians George B. Kober Medal
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Nathan, D. G. Tags: Supplement Source Type: info
CD40Ig treatment results in allograft acceptance mediated by CD8+CD45RClow T cells, IFN-{gamma}, and indoleamine 2,3-dioxygenase
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Guillonneau, C., Hill, M., Hubert, F.-X., Chiffoleau, E., Herve, C., Li, X.-L., Heslan, M., Usal, C., Tesson, L., Menoret, S., Saoudi, A., Le Mauff, B., Josien, R., Cuturi, M. C., Anegon, I. Tags: Research Article Source Type: info
The transition metal gallium disrupts Pseudomonas aeruginosa iron metabolism and has antimicrobial and antibiofilm activity
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Kaneko, Y., Thoendel, M., Olakanmi, O., Britigan, B. E., Singh, P. K. Tags: Research Article Source Type: info
In this issue
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Tags: In This Issue Source Type: info
SPDEF regulates goblet cell hyperplasia in the airway epithelium
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Park, K.-S., Korfhagen, T. R., Bruno, M. D., Kitzmiller, J. A., Wan, H., Wert, S. E., Khurana Hershey, G. K., Chen, G., Whitsett, J. A. Tags: Research Article Source Type: info
When illness goes public: Celebrity patients and how we look at medicine
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Boxer, G. J., Boxer, L. A. Tags: Book Review Source Type: info
Embryonic endocrine pancreas and mature {beta} cells acquire {alpha} and PP cell phenotypes upon Arx misexpression
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Collombat, P., Hecksher-Sorensen, J., Krull, J., Berger, J., Riedel, D., Herrera, P. L., Serup, P., Mansouri, A. Tags: Research Article Source Type: info
gp130 receptor ligands as potential therapeutic targets for obesity
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Febbraio, M. A. Tags: Science in Medicine Source Type: info
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet {beta} cell, regeneration
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Desai, B. M., Oliver-Krasinski, J., De Leon, D. D., Farzad, C., Hong, N., Leach, S. D., Stoffers, D. A. Tags: Research Article Source Type: info
Yin and yang interplay of IFN-{gamma} in inflammation and autoimmune disease
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Zhang, J. Tags: Commentary Source Type: info
Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Sadakata, T., Washida, M., Iwayama, Y., Shoji, S., Sato, Y., Ohkura, T., Katoh-Semba, R., Nakajima, M., Sekine, Y., Tanaka, M., Nakamura, K., Iwata, Y., Tsuchiya, K. J., Mori, N., Detera-Wadleigh, S. D., Ichikawa, H., Itohara, S., Yoshikawa, T., Furuichi, Tags: Research Article Source Type: info
HOX deregulation in acute myeloid leukemia
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Rice, K. L., Licht, J. D. Tags: Commentary Source Type: info
The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Scholl, C., Bansal, D., Dohner, K., Eiwen, K., Huntly, B. J.P., Lee, B. H., Rucker, F. G., Schlenk, R. F., Bullinger, L., Dohner, H., Gilliland, D. G., Frohling, S. Tags: Research Article Source Type: info
Putting pancreatic cell plasticity to the test
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Ferrer, J., Martin, M., Servitja, J. M. Tags: Commentary Source Type: info
Local production of angiotensin II in the subfornical organ causes elevated drinking
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Sakai, K., Agassandian, K., Morimoto, S., Sinnayah, P., Cassell, M. D., Davisson, R. L., Sigmund, C. D. Tags: Research Article Source Type: info
Intersectin links WNK kinases to endocytosis of ROMK1
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: He, G., Wang, H.-R., Huang, S.-K., Huang, C.-L. Tags: Research Article Source Type: info
Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Suh, S. W., Gum, E. T., Hamby, A. M., Chan, P. H., Swanson, R. A. Tags: Research Article Source Type: info
Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Severin, S., Gratacap, M.-P., Lenain, N., Alvarez, L., Hollande, E., Penninger, J. M., Gachet, C., Plantavid, M., Payrastre, B. Tags: Research Article Source Type: info
Genetic analysis of human hematological malignancies rewarded
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Honey, K. Tags: News Source Type: info
Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Lama, V. N., Smith, L., Badri, L., Flint, A., Andrei, A.-C., Murray, S., Wang, Z., Liao, H., Toews, G. B., Krebsbach, P. H., Peters-Golden, M., Pinsky, D. J., Martinez, F. J., Thannickal, V. J. Tags: Research Article Source Type: info
Sickle cell disease: old discoveries, new concepts, and future promise
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Frenette, P. S., Atweh, G. F. Tags: Science in Medicine Source Type: info
Introduction of David G. Nathan, MD: 2006 Association of American Physicians George M. Kober Meda
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Benz, E. J. Tags: Supplement Source Type: info
Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Iwamoto, S., Mihara, K., Downing, J. R., Pui, C.-H., Campana, D. Tags: Research Article Source Type: info
Multi-objective optimization of an industrial penicillin V bioreactor train using non-dominated sorting genetic algorithm
discuss this article
Source: Biotechnology and Bioengineering - April 3, 2007 Authors: Fook Choon Lee, Gade Pandu Rangaiah, Ajay Kumar Ray Source Type: info
Hypoglycemia, functional brain failure, and brain death
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Cryer, P. E. Tags: Commentary Source Type: info
Prenatal dexamethasone exposure induces changes in nonhuman primate offspring cardiometabolic and hypothalamic-pituitary-adrenal axis function
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: de Vries, A., Holmes, M. C., Heijnis, A., Seier, J. V., Heerden, J., Louw, J., Wolfe-Coote, S., Meaney, M. J., Levitt, N. S., Seckl, J. R. Tags: Research Article Source Type: info
Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Rankin, E. B., Biju, M. P., Liu, Q., Unger, T. L., Rha, J., Johnson, R. S., Simon, M. C., Keith, B., Haase, V. H. Tags: Research Article Source Type: info
Artificial lymph nodes induce potent secondary immune responses in naive and immunodeficient mice
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Okamoto, N., Chihara, R., Shimizu, C., Nishimoto, S., Watanabe, T. Tags: Research Article Source Type: info
Generation: The seventeenth-century scientists who unraveled the secrets of sex, life, and growth
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Huhtaniemi, I. T. Tags: Book Review Source Type: info
Thrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model
discuss this article
Source: Journal of Clinical Investigation - April 3, 2007 Authors: Dubois, C., Panicot-Dubois, L., Gainor, J. F., Furie, B. C., Furie, B. Tags: Research Article Source Type: info
HIF-1 and HIF-2: working alone or together in hypoxia?
discuss this article
Sou