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This is a selection of articles from the February 2008 archive. Click here for this month's Biomedical Science headlines.

Basic Blue Skies Research in the UK: Are we losing out?email this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Biomedical Discovery and Collaboration - February 29, 2008 Authors: Belinda Linden Source Type: info

Scaling, growth and cyclicity in biology: a new computational approachemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Theoretical Biology and Medical Modelling - February 29, 2008 Authors: Pier Paolo Delsanto, Antonio S Gliozzi and Caterina Guiot Source Type: info

Circulating vascular endothelial growth factor and systemic inflammatory markers in patients with stable and exacerbated chronic obstructive pulmonary diseaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Clinical Science - February 29, 2008 Authors: Arschang Valipour, Martin Schreder, Michael Wolzt, Sleman Saliba, Sonja Kapiotis, Philipp Eickhoff, Otto Chris Burghuber Source Type: info

Modeling individual-specific human optic nerve head biomechanics. Part I: IOP-induced deformations and influence of geometry.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Biomechanics and Modeling in Mechanobiology - February 29, 2008 Authors: Sigal IA, Flanagan JG, Tertinegg I, Ethier CR Tags: Biomech Model Mechanobiol Source Type: info

Impact of target mRNA structure on siRNA silencing efficiency: A large-scale studyemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 28, 2008 Authors: Joseph A. Gredell, Angela K. Berger, S. Patrick Walton Source Type: info

Immunocytochemical demonstration of polyamines in nucleoli and nucleiemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 27, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Sensitivity of Optical Fiber Sensor Based on Surface Plasmon Resonance: Modeling and Experimentsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Plasmonics - February 27, 2008 Tags: Plasmonics Source Type: info

Effects of Traditional Chinese Medicine on Endotoxin and Its Receptors in Rats with Non-Alcoholic Steatohepatitisemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Inflammation - February 27, 2008 Tags: Inflammation Source Type: info

Japanese Encephalitis Virus Envelope Protein Mitigates TNF-α mRNA Expression in RAW264.7 Cellsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Inflammation - February 27, 2008 Tags: Inflammation Source Type: info

Modeling individual-specific human optic nerve head biomechanics. Part II: influence of material properties.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Biomechanics and Modeling in Mechanobiology - February 27, 2008 Authors: Sigal IA, Flanagan JG, Tertinegg I, Ethier CR Tags: Biomech Model Mechanobiol Source Type: info

Sampling and sensitivity analyses tools (SaSAT) for computational modellingemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Theoretical Biology and Medical Modelling - February 27, 2008 Authors: Alexander Hoare, David G Regan and David P Wilson Source Type: info

Expediting the adaptation processemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 27, 2008 Source Type: info

Stable mammalian cell reporter gene assays in lipophilic chemical screeningemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 27, 2008 Source Type: info

Improving cell performance by engineering oxygen transportemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 27, 2008 Source Type: info

A competitive edge in membrane chromatographyemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 27, 2008 Source Type: info

Retractionemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 27, 2008 Source Type: info

Exfoliation of gastric pit-parietal cells into the gastric lumen associated with a stimulation of isolated rat gastric mucosa in vitro: a morphological study by the application of cryotechniquesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 26, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Three-dimensional immunofluorescent double labelling using polyclonal antibodies derived from the same species: enterocytic colocalization of chylomicrons with Golgi apparatusemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 26, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Thyroid hormone receptor α1–β1 expression in epididymal epithelium from euthyroid and hypothyroid ratsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 26, 2008 Tags: Histochemistry and Cell Biology Source Type: info

NIGMS Image Galleryemail this article save this article to My Clippings discuss this articlediscuss this article
Source: NIGMS Multimedia - February 25, 2008 Authors: National Institute of General Medical Sciences Source Type: info

Lipid droplet changes in proliferating and quiescent 3T3 fibroblastsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 23, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Use of reverse micelles in membrane protein structural biology.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Bimolecular NMR - February 23, 2008 Authors: Van Horn WD, Ogilvie ME, Flynn PF Tags: J Biomol NMR Source Type: info

Design and validation of a system to simulate coronary flexure dynamics on arterial segments perfused ex vivo.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Biomechanics and Modeling in Mechanobiology - February 23, 2008 Authors: Vanepps JS, Londono R, Nieponice A, Vorp DA Tags: Biomech Model Mechanobiol Source Type: info

Rapid translation of fermentation process performanceemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 22, 2008 Source Type: info

Understanding growth factor synergies in cell and tissue engineeringemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 22, 2008 Source Type: info

Queuine promotes antioxidant defense system by activating cellular antioxidant enzyme activities in cancer.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Bioscience Reports - February 22, 2008 Authors: Pathak C, Jaiswal YK, Vinayak M Tags: Biosci Rep Source Type: info

Biostimulation of uranium: Temperature matters!email this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 22, 2008 Source Type: info

Designing sulfur-containing polyesters to like microbesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Biotechnology and Bioengineering - February 22, 2008 Source Type: info

Characterization of human passive muscles for impact loads using genetic algorithm and inverse finite element methods.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Biomechanics and Modeling in Mechanobiology - February 22, 2008 Authors: Chawla A, Mukherjee S, Karthikeyan B Tags: Biomech Model Mechanobiol Source Type: info

Dehydroepiandrosterone and Dehydroepiandrosterone Sulphate in Atopic Allergy and Chronic Urticariaemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Inflammation - February 21, 2008 Tags: Inflammation Source Type: info

Galectin-1 induced activation of the apoptotic death-receptor pathway in human Jurkat T lymphocytesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 21, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Endocytic downregulation of ErbB receptors: mechanisms and relevance in canceremail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 21, 2008 Tags: Histochemistry and Cell Biology Source Type: info

BioMagResBank (BMRB) as a partner in the Worldwide Protein Data Bank (wwPDB): new policies affecting biomolecular NMR depositions.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Bimolecular NMR - February 21, 2008 Authors: Markley JL, Ulrich EL, Berman HM, Henrick K, Nakamura H, Akutsu H Tags: J Biomol NMR Source Type: info

Beyond the Oncogene Paradigm: Understanding Complexity in Cancerogenesis.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Acta Biotheoretica - February 21, 2008 Authors: Bizzarri M, Cucina A, Conti F, D'Anselmi F Tags: Acta Biotheor Source Type: info

Strong Near-infrared Avalanche Photoluminescence from Ag Nanowire Arraysemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Plasmonics - February 19, 2008 Tags: Plasmonics Source Type: info

Ryanodine receptor type-1 (RyR1) expression and protein S-nitrosylation pattern in human soleus myofibres following bed rest and exercise countermeasureemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 19, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Local expression of toll like receptor 4 at the site of ruptured plaques in patients with acute myocardial infarctionemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Clinical Science - February 19, 2008 Authors: Yuh Ishikawa, Mamoru Satoh, Tomonori Itoh, Yoshitaka Minami, Yuji Takahashi, Motoyuki Nakamura Source Type: info

Serum Pro-hepcidin Levels in Rheumatoid Arthritis and Systemic Lupus Erythematosusemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Inflammation - February 17, 2008 Tags: Inflammation Source Type: info

Imaging and imagination: understanding the endo-lysosomal systememail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 15, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Exposure to pro-inflammatory cytokines upregulates MMP-9 synthesis by mesenchymal stem cells-derived osteoprogenitorsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 15, 2008 Tags: Histochemistry and Cell Biology Source Type: info

The peroxisome: still a mysterious organelleemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 15, 2008 Tags: Histochemistry and Cell Biology Source Type: info

A General Formalism for Tissue Morphogenesis Based on Cellular Dynamics and Control System Interactions.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Acta Biotheoretica - February 15, 2008 Authors: Forest L, Demongeot J Tags: Acta Biotheor Source Type: info

Comparison of multiple crystal structures with NMR data for engrailed homeodomain.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Bimolecular NMR - February 15, 2008 Authors: Religa TL Tags: J Biomol NMR Source Type: info

Enhanced NMR signal detection of imino protons in RNA molecules containing 3' dangling nucleotides.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Bimolecular NMR - February 14, 2008 Authors: Amborski AN, Johnson PE Tags: J Biomol NMR Source Type: info

Effect of the Number of Patches in a Multi-patch SIRS Model with Fast Migration on the Basic Reproduction Rate.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Acta Biotheoretica - February 14, 2008 Authors: Kouokam E, Auger P, Hbid H, Tchuente M Tags: Acta Biotheor Source Type: info

Evolution and RNA Relics. A Systems Biology View.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Acta Biotheoretica - February 14, 2008 Authors: Demongeot J, Glade N, Moreira A Tags: Acta Biotheor Source Type: info

GFT projection NMR based resonance assignment of membrane proteins: application to subunit c of E. coli F(1)F (0) ATP synthase in LPPG micelles.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Bimolecular NMR - February 14, 2008 Authors: Zhang Q, Atreya HS, Kamen DE, Girvin ME, Szyperski T Tags: J Biomol NMR Source Type: info

Retrograde traffic in the biosynthetic-secretory routeemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 13, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Immunohistochemical localisation of TRA-1-60, TRA-1-81, GCTM-2 and podocalyxin in the developing baboon kidneyemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 12, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Subcutaneous injection, from birth, of epigallocatechin-3-gallate, a component of green tea, limits the onset of muscular dystrophy in mdx mice: a quantitative histological, immunohistochemical and electrophysiological studyemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 9, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Lysosomes in iron metabolism, ageing and apoptosisemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 8, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Islet β-cell area and hormone expression are unaltered in Huntington’s diseaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 8, 2008 Tags: Histochemistry and Cell Biology Source Type: info

Episode 1: The science of social networksemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Harvard Medical Labcast - February 7, 2008 Authors: Harvard Medical School Office of Public Affairs Source Type: info

In This Issueemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 6, 2008 Source Type: info

The NMR structure of the NIPP1 FHA domain.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Bimolecular NMR - February 6, 2008 Authors: Kumeta H, Ogura K, Adachi S, Fujioka Y, Tanuma K, Kikuchi K, Inagaki F Tags: J Biomol NMR Source Type: info

Determinants of changes in blood glucose response to short-term exercise training in patients with type 2 diabetesemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Clinical Science - February 6, 2008 Authors: Matthew D Hordern, Louise M Cooney, Elaine M Beller, Johannes B Prins, Thomas H Marwick, Jeff S Coombes Source Type: info

Rho GTPases mediated integrin αvβ3 activation in sphingosine-1-phosphate stimulated chemotaxis of endothelial cellsemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Histochemistry and Cell Biology - February 5, 2008 Tags: Histochemistry and Cell Biology Source Type: info

A Mechanistic Investigation of the Algae Growth "Droop" Model.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Acta Biotheoretica - February 5, 2008 Authors: Lemesle V, Mailleret L Tags: Acta Biotheor Source Type: info

Importance of the high molecular weight isoform of adiponectin in improved insulin sensitivity with rosiglitazone treatment in HIV diseaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Clinical Science - February 5, 2008 Authors: Saima Qurashi, Dennis C Mynarcik, Margaret A McNurlan, Hongshik Ahn, Robert Ferris, Marie C Gelato Source Type: info

HIV positive patients treated with protease inhibitors have vascular changes resembling those observed in atherosclerotic cardiovascular diseaseemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Clinical Science - February 5, 2008 Authors: John Lekakis, Sotirios Tsiodras, Ignatios Ikonomidis, John Palios, Garyfalia Poulakou, Loukianos Rallidis, Anastasia Antoniadou, Periklis Panagopoulos, Antonios Papadopoulos, Helen Giamarellou, Dimitrios T Kremastinos Source Type: info

The Double Nucleation Model for Sickle Cell Haemoglobin Polymerization: Full Integration and Comparison with Experimental Data.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Acta Biotheoretica - February 5, 2008 Authors: Medkour T, Ferrone F, Galactéros F, Hannaert P Tags: Acta Biotheor Source Type: info

Imaging Oxygen Distribution in Marine Sediments. The Importance of Bioturbation and Sediment Heterogeneity.email this article save this article to My Clippings discuss this articlediscuss this article
Source: Acta Biotheoretica - February 5, 2008 Authors: Pischedda L, Poggiale JC, Cuny P, Gilbert F Tags: Acta Biotheor Source Type: info

Multipotent adult progenitor cells sustain function of ischemic limbs in miceemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancersemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

Molecular targets for tendon neoformationemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

Claudin-16 and claudin-19 interact and form a cation-selective tight junction complexemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

PPAR{alpha} activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in miceemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

Physiological systems under pressureemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS modelemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

Two tales concerning skeletal muscleemail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

A calculated response: control of inflammation by the innate immune systememail this article save this article to My Clippings discuss this articlediscuss this article
Source: Journal of Clinical Investigation - February 2, 2008 Source Type: info

Loss of PIP5KI{gamma}, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytesemail this article