This is a selection of articles from the February 2007 archive. Click here for this month's Drugs & Pharmacology headlines.
Report: Dementia costs UK £17 billion per year and cases increasing
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Source: NeLM Headline News - February 28, 2007 Tags: 4.11 Drugs for dementia, Dementia, National Health Service, Healthcare statistics / epidemiology, Health Economics Source Type: news
Effects of medical therapy on insulin resistance and the cardiovascular system in Polycystic Ovary Syndrome
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Source: NeLM Headline News - February 28, 2007 Tags: 6.1.2 Oral antidiabetic drugs, 7.3.1 Combined hormonal contraceptives, Endocrinology, Obstetrics & amp; Gynaecology Source Type: news
Positive association between gastro-oesophageal reflux disease and irritable bowel syndrome in a Chinese population
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Source: Alimentary Pharmacology and Therapeutics - February 28, 2007 Source Type: news
Association and linkage analysis of COL1A1 and AHSG gene polymorphisms with femoral neck bone geometric parameters in both Caucasian and Chinese nuclear families5
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Source: Acta Pharmacologica Sinica - February 28, 2007 Tags: Original Articles Source Type: news
Comparative study of doxorubicin-loaded poly(lactide-co-glycolide) nanoparticles prepared by single and double emulsion methods.
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Source: European Journal of Pharmaceutics and Biopharmaceutics - February 28, 2007 Authors: Tewes F, Munnier E, Antoon B, Ngaboni Okassa L, Cohen-Jonathan S, Marchais H, Douziech-Eyrolles L, Soucé M, Dubois P, Chourpa I Tags: Eur J Pharm Biopharm Source Type: news
The concentration-dependent effects of ethanol on Caenorhabditis elegans behaviour
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Source: The Pharmacogenomics Journal - February 27, 2007 Authors: P H MitchellK BullS GlautierN A HopperL Holden-DyeV O'Connor Source Type: news
Low frequency of CYP2D6 poor metabolizers among schizophrenia patients
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Source: The Pharmacogenomics Journal - February 27, 2007 Authors: A LLerenaP DoradoE M Peñas-LLedóM C CáceresA De la Rubia Source Type: news
Docs don't want pharmacies to share Rx data
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Source: Drug Topics - News - February 26, 2007 Source Type: news
Use of benzodiazepines and benzodiazepine receptor agonists during pregnancy: maternal characteristics
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Source: Pharmacoepidemiology and Drug Safety - February 26, 2007 Authors: Birgitta Norstedt Wikner, Carl-Olav Stiller, Bengt Källén, Charlotte Asker Source Type: news
Use of other EPO agents may also increase risk
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Source: Drug Topics - News - February 26, 2007 Source Type: news
FTY720 suppresses interleukin-1β-induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism
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Source: British Journal of Pharmacology - February 26, 2007 Authors: C XinS RenW EberhardtJ PfeilschifterA Huwiler Source Type: news
Licensing Highlights
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Source: IDrugs - February 26, 2007 Authors: J Bright, J Shumoogam and S Tear Source Type: news
AMPA receptor potentiators as cognitive enhancers
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Source: IDrugs - February 26, 2007 Authors: MJ O'Neill and S Dix Source Type: news
The interaction of host genetic factors and Helicobacter pylori infection
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Source: Inflammopharmacology - February 25, 2007 Tags: Inflammopharmacology Source Type: news
High dose zinc linked to increased genitourinary admissions.
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Source: Reactions Weekly - February 24, 2007 Tags: HTML Source Type: news
Hydroxychloroquine: Toxic myopathy leading to respiratory failure in an elderly patient: case report.
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Source: Reactions Weekly - February 24, 2007 Tags: HTML Source Type: news
Lenograstim: Marrow expansion in a child: case report.
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Source: Reactions Weekly - February 24, 2007 Tags: HTML Source Type: news
Rituximab: Bronchiolitis obliterans with organising pneumonia: case report.
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Source: Reactions Weekly - February 24, 2007 Tags: HTML Source Type: news
Medicaid access restrictions impact statin use.
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Source: PharmacoEconomics & Outcomes News - February 24, 2007 Tags: HTML Source Type: news
The US NCCN * has updated its Breast Cancer Risk Reduction guidelines.
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Source: PharmacoEconomics & Outcomes News - February 24, 2007 Tags: HTML Source Type: news
In patients with atrial fibrillation, warfarin therapy commenced prior to detection of left atrial thrombus (LAT) reduces the incidence of stroke.
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Source: Inpharma Weekly - February 24, 2007 Tags: HTML Source Type: news
Sevoflurane a possible alternative to nitrous oxide during labour.
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Source: Inpharma Weekly - February 24, 2007 Tags: HTML Source Type: news
When the evidence is strong enough without randomisation.
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Source: Inpharma Weekly - February 24, 2007 Tags: HTML Source Type: news
Tumour concentrations of paclitaxel are markedly increased when it is administered with a cholesterol-rich nanoemulsion (LDE) in women with gynaecologic cancer,.
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Source: Inpharma Weekly - February 24, 2007 Tags: HTML Source Type: news
Lenalidomide with or without dexamethasone in amyloidosis.
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Source: Inpharma Weekly - February 24, 2007 Tags: HTML Source Type: news
Two artesunate-based therapies for malaria are also effective in the treatment of schistosomiasis in children,.
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Source: Inpharma Weekly - February 24, 2007 Tags: HTML Source Type: news
Mapping the contribution of beta3-containing GABAAreceptors to volatile and intravenous general anesthetic actions
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Source: BMC Pharmacology - February 24, 2007 Authors: Anja Zeller, Margarete Arras, Rachel Jurd and Uwe Rudolph Source Type: news
Erythropoietins: mortality warning extends to use in cancer.
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Source: Reactions Weekly - February 23, 2007 Tags: HTML Source Type: news
Pneumococcal vaccination worth it for the elderly in Italy?
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Source: PharmacoEconomics & Outcomes News - February 23, 2007 Tags: HTML Source Type: news
Population pharmacokinetics of melphalan in paediatric blood or marrow transplant recipients
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Source: British Journal of Clinical Pharmacology - February 23, 2007 Tags: Original Articles Source Type: news
EFFECT OF HIGH SALT INTAKE ON LOCAL RENIN–ANGIOTENSIN SYSTEM AND VENTRICULAR DYSFUNCTION FOLLOWING MYOCARDIAL INFARCTION IN RATS
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Source: Clinical and Experimental Pharmacology and Physiology - February 23, 2007 Tags: Original Articles Source Type: news
DIFFERENTIAL EFFECTS OF VASOPRESSINERGIC AND OXYTOCINERGIC PRE-AUTONOMIC NEURONS ON CIRCULATORY CONTROL: REFLEX MECHANISMS AND CHANGES DURING EXERCISE
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Source: Clinical and Experimental Pharmacology and Physiology - February 23, 2007 Tags: Experimental Biology 2006 Activity-Dependent Plasticity in Central Homeostatic Systems Source Type: news
Amiodarone Prophylaxis for Atrial Fibrillation After Cardiac Surgery: Meta-Analysis of Dose Response and Timing of Initiation
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Source: Pharmacotherapy: Official Journal of the American College of Clinical Pharmacy - February 23, 2007 Authors: Mitchell S BuckleyPaul E NolanMarion K SlackJames E TisdaleDaniel E HillemanJack G Copeland Source Type: news
Neuroprotective effect of L-kynurenine sulfate administered before focal cerebral ischemia in mice and global cerebral ischemia in gerbils.
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Source: European Journal of Pharmacology - February 23, 2007 Authors: Gigler G, Szénási G, Simó A, Lévay G, Hársing LG, Sas K, Vécsei L, Toldi J Tags: Eur J Pharmacol Source Type: news
Extent of Supercoiling in Plasmid DNA Vaccines: Should Restrictions be Relaxed?
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Source: American Journal of Drug Delivery - February 22, 2007 Tags: Abstract HTML PDF (246 K) Source Type: news
Case report: Hypersensitivity to insulin detemir
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Source: NeLM Headline News - February 22, 2007 Tags: 6.1.1 Insulins, Diabetes, Adverse Drug Reactions, New drugs, Allergy Source Type: news
King’s Fund responds to NHS financial performance report
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Source: NeLM Headline News - February 20, 2007 Source Type: news
Study looking at the effect of erythropoietin on quality of life in patients with NSCLC and disease-related anaemia stopped early due to higher survival in the placebo group
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Source: NeLM Headline News - February 20, 2007 Source Type: news
Conscientious Objection: A Pharmacist's Right or Professional Negligence?
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Source: Medscape Pharmacist Headlines - February 20, 2007 Tags: Pharmacist Source Type: news
Pyrazole trk kinase inhibitors for the treatment of cancerAstraZeneca: WO06087538 and WO06087530
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Source: Expert Opinion: Expert Opinion on Therapeutic Patents: Table of Contents - February 20, 2007 Tags: Patent Evaluation Source Type: news
Postoperative pain management: new, convenient analgesic therapies
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Source: Expert Opinion: Expert Opinion on Pharmacotherapy: Table of Contents - February 19, 2007 Tags: Review Source Type: news
Comparison of outcome of two antibiotic prophylaxis regimes for sternal wound infection in high risk patients following CABG
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Source: NeLM Headline News - February 19, 2007 Tags: 5.1 Antibacterial drugs, Bacterial, Cardiac Surgery, Preventative medicines Source Type: news
Intensive insulin treatment during cardiac surgery has no benefits and may be harmful
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Source: NeLM Headline News - February 19, 2007 Tags: Cardiac Surgery, Endocrinology, 6.1.1 Insulins Source Type: news
Darifenacin: a muscarinic M3-selective receptor antagonist for the treatment of overactive bladder
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Source: Expert Opinion: Expert Opinion on Pharmacotherapy: Table of Contents - February 19, 2007 Tags: Drug Evaluation Source Type: news
Management of cancer from an unknown primary
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Source: Expert Opinion: Expert Opinion on Pharmacotherapy: Table of Contents - February 19, 2007 Tags: Review Source Type: news
Abacavir sulfate/lamivudine/zidovudine fixed combination in the treatment of HIV infection
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Source: Expert Opinion: Expert Opinion on Pharmacotherapy: Table of Contents - February 19, 2007 Tags: Drug Evaluation Source Type: news
Immunogenicity screening in protein drug development
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Source: Expert Opinion: Expert Opinion on Biological Therapy: Table of Contents - February 19, 2007 Tags: Technology Evaluation Source Type: news
Role of monoclonal antibodies in tumor-specific immunity
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Source: Expert Opinion: Expert Opinion on Biological Therapy: Table of Contents - February 19, 2007 Tags: Review Source Type: news
Erythropoiesis-stimulating agent (Aranesp)
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Source: West Midlands Centre for Adverse Drug Reactions - February 19, 2007 Authors: anthony.cox Tags: FDA ADRs Source Type: news
Groups collaborate on pneumonia guidelines
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Source: Drug Topics - Drug Information - February 19, 2007 Source Type: news
In vivo and in vitro antiviral activity of hyperoside extracted from Abelmoschus manihot (L) medik.
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Source: Acta Pharmacologica Sinica - February 18, 2007 Authors: Wu LL, Yang XB, Huang ZM, Liu HZ, Wu GX Tags: Acta Pharmacol Sin Source Type: news
ORAL OLIGOFRUCTOSE-ENRICHED INULIN SUPPLEMENTATION IN ACUTE ULCERATIVE COLITIS IS WELL TOLERATED AND ASSOCIATED WITH LOWERED FAECAL CALPROTECTIN
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Source: Alimentary Pharmacology and Therapeutics - February 17, 2007 Source Type: news
Clomifene: Manic delirium in a patient with bipolar I disorder: case report.
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Source: Reactions Weekly - February 16, 2007 Tags: HTML Source Type: news
Linezolid: Optic neuropathy in a child: case report.
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Source: Reactions Weekly - February 16, 2007 Tags: HTML Source Type: news
Cotrimoxazole/clindamycin/primaquine: Exanthema and methaemoglobinaemia: case report.
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Source: Reactions Weekly - February 16, 2007 Tags: HTML Source Type: news
Testosterone enantate: Prostate cancer (first report) in an elderly patient who had received radiotherapy: case report.
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Source: Reactions Weekly - February 16, 2007 Tags: HTML Source Type: news
Early steroid withdrawal regimen effective in renal transplant.
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Source: Inpharma Weekly - February 16, 2007 Tags: HTML Source Type: news
Shionogi has launched 0.5% oxycodone [OxiNorm] powder for cancer pain in Japan.
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Source: Inpharma Weekly - February 16, 2007 Tags: HTML Source Type: news
Cutting the use of benzodiazepines among the elderly by over 50% did not lead to a corresponding decrease in hip fractures,.
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Source: Inpharma Weekly - February 16, 2007 Tags: HTML Source Type: news
FDA-approved phenylephrine decongestant dose questioned.
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Source: Inpharma Weekly - February 16, 2007 Tags: HTML Source Type: news
Quadrivalent recombinant HPV vaccine: safety concerns.
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Source: Inpharma Weekly - February 16, 2007 Tags: HTML Source Type: news
Model-based drug development applied to oncology
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Source: Expert Opinion: Expert Opinion on Drug Discovery: Table of Contents - February 16, 2007 Tags: Review Source Type: news
Review article: update on gastro-oesophageal reflux disease in children
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Source: Alimentary Pharmacology - February 16, 2007 Tags: Review articles Source Type: news
PTI-821: sustained-release oxycodone using gel-cap technology
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Source: Expert Opinion: Expert Opinion on Investigational Drugs: Table of Contents - February 16, 2007 Tags: Drug Evaluation Source Type: news
The CoPrescription of Contraindicated Drugs With Statins: Continuing Potential for Increased Risk of Adverse Events.
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Source: American Journal of Therapeutics - February 16, 2007 Tags: Abstract HTML PDF (112 K) Source Type: news
Effect of Itraconazole on Pharmacokinetics of Paroxetine: The Role of Gut Transporters.
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Source: Therapeutic Drug Monitoring - February 16, 2007 Tags: Abstract HTML PDF (74 K) Source Type: news
Validation of Immunological Biomarkers for the Pharmacodynamic Monitoring of Immunosuppressive Drugs in Humans.
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Source: Therapeutic Drug Monitoring - February 16, 2007 Tags: Abstract HTML PDF (325 K) Source Type: news
Involvement of reactive oxygen species on the apoptotic mechanism induced by IFN-alpha2b in rat preneoplastic liver.
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Source: Biochemical Pharmacology - February 16, 2007 Authors: Quiroga AD, Alvarez MD, Parody JP, Ronco MT, Francés DE, Pisani GB, Carnovale CE, Carrillo MC Tags: Biochem Pharmacol Source Type: news
Application to FDA for new treatment indications of sitagliptin (Januvia) for diabetes mellitis
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Source: NeLM Headline News - February 15, 2007 Tags: 6.1.2 Oral antidiabetic drugs, Diabetes, Licence extension, Food & amp; Drug Administration (FDA) Source Type: news
FDA Approvals: OTC alli and Tirosint
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Source: Medscape Pharmacist Headlines - February 15, 2007 Tags: Pharmacist Source Type: news
National Prescribing Centre (NPC): Achieving Concordance for Taking Medicines
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