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This is a selection of articles from the November 2007 archive. Click here for this month's Drugs & Pharmacology headlines.

Dual roles of NF-κB in cell survival and implications of NF-κB inhibitors in neuroprotective therapy1 discuss this article
Source: Acta Pharmacologica Sinica - November 30, 2007 Tags: article Review Source Type: journals

FDA Approves Cymbalta for Maintenance Treatment of Major Depressive Disorder discuss this article
Source: Drugs.com - New Drug Approvals - November 30, 2007 Source Type: journals

Formulation of Controlled-Release Baclofen Matrix Tablets: Influence of Some Hydrophilic Polymers on the Release Rate and In Vitro Evaluation discuss this article
Source: AAPS PharmSciTech - November 30, 2007 Source Type: journals

Novel risk-sharing scheme puts the spotlight on biomarkers discuss this article
Source: Nature Reviews Drug Discovery - November 30, 2007 Authors: Bethan Hughes Tags: News and Analysis Source Type: journals

Effects of GSM 1800 MHz on dendritic development of cultured hippo-campal neurons1 discuss this article
Source: Acta Pharmacologica Sinica - November 30, 2007 Tags: article Original Articles Source Type: journals

Enhanced sensitivity of hepatocellular carcinoma cells to chemotherapy with a Smac-armed oncolytic adenovirus1 discuss this article
Source: Acta Pharmacologica Sinica - November 30, 2007 Tags: article Original Articles Source Type: journals

METHYLENE BLUE INCREASES CONTRALATERAL TESTICULAR ISCHAEMIA–REPERFUSION INJURY AFTER UNILATERAL TESTICULAR TORSION discuss this article
Source: Clinical and Experimental Pharmacology and Physiology - November 30, 2007 Tags: article Original Articles Source Type: journals

Naltrexone Hyrdochloride(Naltrexone Hydrochloride) Tablet, Film Coated [Mallinckrodt Inc.] discuss this article
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 30, 2007 Source Type: journals

Anzemet(Dolasetron Mesylate) Injection [Sanofi-Aventis U.S. LLC] discuss this article
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 30, 2007 Source Type: journals

Assessment of Pharmacokinetics and Pharmacodynamic Effects Related to Abuse Potential of a Unique Oral Osmotic-Controlled Extended-Release Methylphenidate Formulation in Humans discuss this article
Source: The Journal of Clinical Pharmacology - November 29, 2007 Authors: Parasrampuria, D. A., Schoedel, K. A., Schuller, R., Gu, J., Ciccone, P., Silber, S. A., Sellers, E. M. Tags: Pharmacokinetics and Pharmacodynamics Source Type: journals

Suspension of UK marketing authorisations for aprotinin (Trasylol) discuss this article
Source: NeLM Headline News - November 28, 2007 Tags: 2.11 Antifibrinolytic drugs and haemostatics, Cardiac Surgery, Adverse Drug Reactions, Medicines and Healthcare products Regulatory Agency (MHRA), Product Licence Changes, Unlicenced medicines Source Type: journals

The potential link between atherosclerosis and the 5-lipoxygenase pathway: investigational agents with new implications for the cardiovascular field discuss this article
Source: Expert Opinion: Expert Opinion on Investigational Drugs: Table of Contents - November 28, 2007 Tags: Review Source Type: journals

Lung cancer and regular use of aspirin and nonaspirin nonsteroidal anti-inflammatory drugs discuss this article
Source: Pharmacoepidemiology and Drug Safety - November 28, 2007 Authors: Judith P. Kelly, Patricia Coogan, Brian L. Strom, Lynn Rosenberg Source Type: journals

Topiramate: First report of heat stroke: 3 case reports. discuss this article
Source: Reactions Weekly - November 27, 2007 Tags: HTML Source Type: journals

Risperidone: Enuresis in children with autistic disorder: 2 case reports. discuss this article
Source: Reactions Weekly - November 27, 2007 Tags: HTML Source Type: journals

Avandia's boxed warning revised to include heart attack. discuss this article
Source: Reactions Weekly - November 27, 2007 Tags: HTML Source Type: journals

Amiodarone: Bone marrow granulomas and hyperthyroidism in elderly patients: 2 case reports. discuss this article
Source: Reactions Weekly - November 27, 2007 Tags: HTML Source Type: journals

Atorvastatin interaction: Interaction with concomitant fluconazole leading to rhabdomyolysis in an elderly patient: case report. discuss this article
Source: Reactions Weekly - November 27, 2007 Tags: HTML Source Type: journals

Tacrolimus: Optic neuritis in an elderly renal transplant recipient: case report. discuss this article
Source: Reactions Weekly - November 27, 2007 Tags: HTML Source Type: journals

Lamotrigine appears promising in the treatment of compulsive skin picking,. discuss this article
Source: Inpharma Weekly - November 27, 2007 Tags: HTML Source Type: journals

EU product launches. discuss this article
Source: Inpharma Weekly - November 27, 2007 Tags: HTML Source Type: journals

The Role of Xanthine Oxidase in Thiopurine Metabolism: A Case Report. discuss this article
Source: Therapeutic Drug Monitoring - November 27, 2007 Tags: Abstract HTML PDF (149 K) Source Type: journals

Population Pharmacokinetic Model of Carbamazepine Derived from Routine Therapeutic Drug Monitoring Data. discuss this article
Source: Therapeutic Drug Monitoring - November 27, 2007 Tags: Abstract HTML PDF (196 K) Source Type: journals

Acknowledgement. discuss this article
Source: Drug Safety - November 27, 2007 Tags: HTML PDF (108 K) Source Type: journals

Health Care Costs and Medication Adherence Associated with Initiation of Insulin Pen Therapy in Medicaid-Enrolled Patients with Type 2 Diabetes: A Retrospective Database Analysis. discuss this article
Source: Clinical Therapeutics - November 27, 2007 Authors: Pawaskar MD, Camacho FT, Anderson RT, Cobden D, Joshi AV, Balkrishnan R Tags: Clin Ther Source Type: journals

Key Articles and Guidelines in the Management of Acute Coronary Syndromes and in Percutaneous Coronary Intervention: 2007 Update discuss this article
Source: Pharmacotherapy: Official Journal of the American College of Clinical Pharmacy - November 27, 2007 Authors: Paul P DobeshSara D BrouseWilliam E DagerSarah A SpinlerZachary StacyBarbara S Wiggins Source Type: journals

NPCi blog: Awareness, agreement, adoption and adherence to hypertension guideline recommendations discuss this article
Source: NeLM Headline News - November 26, 2007 Source Type: journals

Marketing application for vorinostat filed in Europe for the treatment of advanced, refractory cutaneous T-Cell lymphoma discuss this article
Source: NeLM Headline News - November 26, 2007 Source Type: journals

EC approves temsirolimus (Torisel) for advanced renal cell carcinoma discuss this article
Source: NeLM Headline News - November 26, 2007 Source Type: journals

Erratum discuss this article
Source: Inflammopharmacology - November 26, 2007 Tags: Inflammopharmacology Source Type: journals

Idiopathic chronic facial pain: Tricyclic antidepressant drug action is not due to free radical scavenging (antioxidant) activity discuss this article
Source: Inflammopharmacology - November 26, 2007 Tags: Inflammopharmacology Source Type: journals

Cefuroxime axetil: First report of cutaneous lupus erythematosus: case report discuss this article
Source: Reactions - November 26, 2007 Tags: Short communication Source Type: journals

Varicella zoster virus vaccine live: Chickenpox in an infant: case report discuss this article
Source: Reactions - November 26, 2007 Tags: Short communication Source Type: journals

Atorvastatin interaction: Interaction with concomitant fluconazole leading to rhabdomyolysis in an elderly patient: case report discuss this article
Source: Reactions - November 26, 2007 Tags: Short communication Source Type: journals

Hypersensitivity to be added to strontium ranelate label discuss this article
Source: Reactions - November 26, 2007 Tags: Short communication Source Type: journals

Mipomersen sodium is a promising treatment for hypercholesterolaemia, and has a favourable safety profile discuss this article
Source: Inpharma - November 26, 2007 Tags: Short communication Source Type: journals

Dasatinib for the treatment of Philadelphia chromosome-positive chronic myelogenous leukaemia after imatinib failure discuss this article
Source: Expert Opinion: Expert Opinion on Pharmacotherapy: Table of Contents - November 26, 2007 Tags: Drug Evaluation Source Type: journals

Pharmacotherapy for bronchiectasis discuss this article
Source: Expert Opinion: Expert Opinion on Pharmacotherapy: Table of Contents - November 26, 2007 Tags: Review Source Type: journals

PhRMA encouraged by number of HIV therapies in development discuss this article
Source: Drug Topics - Drug Information - November 26, 2007 Source Type: journals

Conferences Diary discuss this article
Source: IDrugs - November 26, 2007 Source Type: journals

Discovery on Target 2007 - CHI's Fifth Annual Conference. RNAi for Drug Discovery and Therapeutics discuss this article
Source: IDrugs - November 26, 2007 Authors: Y Shen Source Type: journals

Gender-specific vascular effects elicited by chronic ethanol consumption in rats: a role for inducible nitric oxide synthase discuss this article
Source: British Journal of Pharmacology - November 26, 2007 Authors: C R TirapelliS Y FukadaA YogiA Z ChignaliaR C TostesD BonaventuraV L LanchoteF Q CunhaA M de Oliveira Source Type: journals

AACR-NCI-EORTC - 19th Symposium. Molecular Targets and Cancer Therapeutics - Part 2 discuss this article
Source: IDrugs - November 26, 2007 Authors: B Searle and T Collins Source Type: journals

Rule-based standardised switching of drugs at the interface between primary and tertiary care discuss this article
Source: European Journal of Clinical Pharmacology - November 25, 2007 Tags: European Journal of Clinical Pharmacology Source Type: journals

Infliximab dose escalation vs. initiation of adalimumab for loss of response in Crohn’s disease: a cost-effectiveness analysis discuss this article
Source: Alimentary Pharmacology and Therapeutics - November 23, 2007 Tags: article Original articles Source Type: journals

Schizophrenia drug gains new indication for maintenance treatment discuss this article
Source: Drug Topics - Hot off the Press - November 23, 2007 Source Type: journals

Triptolide inhibits NF-kappaB activation and reduces injury of donor lung induced by ischemia/reperfusion. discuss this article
Source: Acta Pharmacologica Sinica - November 23, 2007 Authors: He JK, Yu SD, Zhu HJ, Wu JC, Qin ZH Tags: Acta Pharmacol Sin Source Type: journals

Fluvastatin inhibits activation of JAK and STAT proteins in diabetic rat glomeruli and mesangial cells under high glucose conditions. discuss this article
Source: Acta Pharmacologica Sinica - November 23, 2007 Authors: Shi YH, Zhao S, Wang C, Li Y, Duan HJ Tags: Acta Pharmacol Sin Source Type: journals

Silencing livin gene by siRNA leads to apoptosis induction, cell cycle arrest, and proliferation inhibition in malignant melanoma LiBr cells. discuss this article
Source: Acta Pharmacologica Sinica - November 23, 2007 Authors: Wang H, Tan SS, Wang XY, Liu DH, Yu CS, Bai ZL, He DL, Zhao J Tags: Acta Pharmacol Sin Source Type: journals

Cost Effectiveness of Lopinavir/Ritonavir Tablets Compared with Atazanavir plus Ritonavir in Antiretroviral-Experienced Patients in the UK, France, Italy and Spain discuss this article
Source: Clinical Drug Investigation - November 22, 2007 Authors: Simpson, Kit N.Jones, Walter J.Rajagopalan, RukminiDietz, Birgitta Tags: Original Research Article Source Type: journals

Regulation of Therapeutic Research is Compromising the Interests of Patients1. discuss this article
Source: International Journal of Pharmaceutical Medicine - November 21, 2007 Tags: Abstract HTML PDF (201 K) Source Type: journals

Hearing in Children With Fetal Alcohol Spectrum Disorder (FASD). discuss this article
Source: Can J Clin Pharmacol - November 21, 2007 Authors: Cohen-Kerem R, Bar-Oz B, Nulman I, Papaioannou VA, Koren G Tags: Can J Clin Pharmacol Source Type: journals

Meta-analysis of studies investigating one-year effectiveness of transdermal nicotine patches for smoking cessation discuss this article
Source: NeLM Headline News - November 21, 2007 Tags: 4.10 Drugs used in substance dependence, Smoking Source Type: journals

Oligostilbenoids from Shorea gibbosa and their cytotoxic properties against P-388 cells discuss this article
Source: Journal of Natural Medicines - November 21, 2007 Tags: Journal of Natural Medicines Source Type: journals

Physiologically based approaches towards the prediction of pharmacokinetics: in vitro–in vivo extrapolation discuss this article
Source: Expert Opinion: Expert Opinion on Drug Metabolism & Toxicology: Table of Contents - November 21, 2007 Tags: Review Source Type: journals

Dose-response effect of ellagic acid on circulatory antioxidants and lipids during alcohol-induced toxicity in experimental rats discuss this article
Source: Fundamental and Clinical Pharmacology - November 21, 2007 Tags: article ORIGINAL ARTICLES Source Type: journals

Although Raynaud's phenomenon is common, it usually only requires pharmacological treatment in some patients. discuss this article
Source: Drugs & Therapy Perspectives - November 20, 2007 Tags: Abstract HTML PDF (162 K) Source Type: journals

Benefit from beta-blockade after MI is seen early discuss this article
Source: NeLM Headline News - November 20, 2007 Source Type: journals

DoH publication: Research evidence on the effectiveness of self care support discuss this article
Source: NeLM Headline News - November 20, 2007 Source Type: journals

Keppra(Levetiracetam) Tablet, Film Coated Keppra(Levetiracetam) Solution [UCB Inc.] discuss this article
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - November 20, 2007 Source Type: journals

Prasugrel: greater platelet inhibition than clopidogrel discuss this article
Source: Inpharma - November 19, 2007 Tags: Research article Source Type: journals

BioRx has launched a SC human immune globulin therapy [Vivaglobin] in the US for immunoglobulin replacement in patients with PIDD discuss this article
Source: Inpharma - November 19, 2007 Tags: Short communication Source Type: journals

Stem cell therapy news from AHA discuss this article
Source: Inpharma - November 19, 2007 Tags: Short communication Source Type: journals

Cycloserine may increase the efficacy of exposure therapy in patients with obsessive-compulsive disorder (OCD) discuss this article
Source: Inpharma - November 19, 2007 Tags: Research article Source Type: journals

Beclometasone/formoterol for asthma cost saving in Spain discuss this article
Source: Inpharma - November 19, 2007 Tags: Research article Source Type: journals

Antipsychotic compliance valuable in schizophrenia discuss this article
Source: Inpharma - November 19, 2007 Tags: Research article Source Type: journals

Molecular mechanisms of cellular senescence and immortalization of human cells discuss this article
Source: Expert Opinion: Expert Opinion on Therapeutic Targets: Table of Contents - November 19, 2007 Tags: Review Source Type: journals

Age Intervention Eyelash discuss this article
Source: Drugs.com - FDA MedWatch Alerts - November 19, 2007 Source Type: journals

The leptin hypothesis of depression: a potential link between mood disorders and obesity? discuss this article
Source: Current Opinion in Pharmacology - November 19, 2007 Authors: Lu XY Tags: Curr Opin Pharmacol Source Type: journals

New injectable antibiotic welcomed with open arms discuss this article
Source: Drug Topics - Drug Information - November 19, 2007 Source Type: journals

Guidance on the assessment of pain in older people