This is a selection of articles from the December 2007 archive. Click here for this month's Drugs & Pharmacology headlines.
Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations.
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Source: Drug Resistance Updates - December 29, 2007 Authors: Lopiccolo J, Blumenthal GM, Bernstein WB, Dennis PA Tags: Drug Resist Updat Source Type: info
Advances in Treatment for Ankylosing Spondylitis and Other Rheumatic Conditions -- Efficacy and Safety of TNF Inhibitors
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Source: Medscape Pharmacist Headlines - December 28, 2007 Tags: Rheumatology Source Type: info
Vildagliptin Effective Monotherapy for Treatment-Naive Elderly Type 2 Diabetics
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Source: Medscape Pharmacist Headlines - December 28, 2007 Tags: Diabetes & Endocrinology Source Type: info
Influence of Selected Formulation Variables on the Preparation of Enzyme-entrapped Eudragit S100 Microspheres
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Source: AAPS PharmSciTech - December 27, 2007 Source Type: info
Orlistat-Associated Adverse Effects and Drug Interactions: A Critical Review.
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Source: Drug Safety - December 27, 2007 Tags: Abstract HTML PDF (216 K) Source Type: info
Adenovirus viral interleukin-10 inhibits adhesion molecule expressions induced by hypoxia/reoxygenation in cerebrovascular endothelial cells.
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Source: Acta Pharmacologica Sinica - December 27, 2007 Authors: Kang H, Yang PY, Rui YC Tags: Acta Pharmacol Sin Source Type: info
EFFECTS OF SWIMMING EXERCISE AND SOYBEAN SUPPLEMENTATION ON THE IMMUNE FUNCTIONS OF RATS FED A HIGH-FAT DIET
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Source: Clinical and Experimental Pharmacology and Physiology - December 27, 2007 Tags: article Original Articles Source Type: info
PPAR-γ ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo
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Source: Investigational New Drugs - December 27, 2007 Tags: Investigational New Drugs Source Type: info
AMP-ACTIVATED PROTEIN KINASE ACTIVATION AS A STRATEGY FOR PROTECTING VASCULAR ENDOTHELIAL FUNCTION
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Source: Clinical and Experimental Pharmacology and Physiology - December 26, 2007 Tags: article Brief Review Source Type: info
Benefits and Risks of Antipsychotic Polypharmacy: An Evidence-Based Review of the Literature
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Source: Drug Safety - December 24, 2007 Authors: Tranulis, ConstantinSkalli, LeilaLalonde, PierreNicole, LucStip, Emmanuel Tags: Review Article Source Type: info
Skeletal muscle expresses the extracellular cyclic AMP–adenosine pathway
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Source: British Journal of Pharmacology - December 24, 2007 Authors: T ChiavegattiV L CostaM S AraújoR O Godinho Source Type: info
Pfizer receives approvable letter from US FDA for dalbavancin
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Source: NeLM Headline News - December 23, 2007 Tags: 5.1 Antibacterial drugs, Bacterial, New drugs, Food & amp; Drug Administration (FDA) Source Type: info
Trends in the consumption of opioid analgesics in Spain. Higher increases as fentanyl replaces morphine
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Source: European Journal of Clinical Pharmacology - December 23, 2007 Tags: European Journal of Clinical Pharmacology Source Type: info
Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes
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Source: European Journal of Clinical Pharmacology - December 22, 2007 Tags: European Journal of Clinical Pharmacology Source Type: info
Tandutinib, an oral, small-molecule inhibitor of FLT3 for the treatment of AML and other cancer indications
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Source: IDrugs - December 21, 2007 Authors: Y Cheng and K Paz Source Type: info
Society for Neuroscience – 37th Annual Meeting - Experimental pharmacotherapeutics for schizophrenia and addiction
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Source: IDrugs - December 21, 2007 Authors: U Jahnke Source Type: info
Xenon(Xenon, XE-133) Gas [Bristol-Myers Squibb]
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Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - December 21, 2007 Source Type: info
Zometa(Zoledronic Acid) Injection, Solution, Concentratefor Intravenous Use [Novartis Pharmaceuticals Corporation]
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Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - December 21, 2007 Source Type: info
Conferences Diary
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Source: IDrugs - December 21, 2007 Source Type: info
Heparin Lock Flush Solution (Pre-Filled 5 ml in 12 ml Syringes)
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Source: Drugs.com - FDA MedWatch Alerts - December 21, 2007 Source Type: info
Novel chemotherapy for tuberculosis: chemotherapeutic potential of econazole- and moxifloxacin-loaded PLG nanoparticles.
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Source: International Journal of Antimicrobial Agents - December 21, 2007 Authors: Ahmad Z, Pandey R, Sharma S, Khuller GK Tags: Int J Antimicrob Agents Source Type: info
New pneumococcal vaccine 'does save lives' - as more parents urged to vaccinate their children
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Source: NeLM Headline News - December 20, 2007 Source Type: info
FDA Approvals: Cymbalta, Sprycel, Seroquel XR
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Source: Medscape Pharmacist Headlines - December 20, 2007 Tags: Pharmacist Source Type: info
FDA's final rule requires warning for nonoxynol 9 OTC contraceptives
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Source: Drug Topics - Hot off the Press - December 20, 2007 Source Type: info
Modeling of drug-transporter interactions using structural information
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Source: Current Opinion in Drug Discovery & Development - December 20, 2007 Authors: S Winiwarter and C Hilgendorf Source Type: info
The presence of beta2-adrenoceptors sensitizes alpha2A-adrenoceptors to desensitization after chronic epinephrine treatment
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Source: BMC Pharmacology - December 20, 2007 Authors: Tasneem Bawa-Khalfe, Ghazi F Altememi, Chitra D Mandyam, Lindsay A Schwarz, Douglas C Eikenburg and Kelly M Standifer Source Type: info
Targeting HIV Attachment and Entry for Therapy.
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Source: Advances in Pharmacology - December 19, 2007 Authors: Strizki J Tags: Adv Pharmacol Source Type: info
Viral drug resistance and fitness.
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Source: Advances in Pharmacology - December 19, 2007 Authors: Quiñones-Mateu ME, Moore-Dudley DM, Jegede O, Weber J, J Arts E Tags: Adv Pharmacol Source Type: info
New drug application submitted to US FDA for ferumoxytol for iron deficiency anaemia in patients with chronic kidney disease
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Source: NeLM Headline News - December 19, 2007 Tags: 9.1.3 Drugs used in hypoplastic, haemolytic, and renal anaemias, Anaemias, Renal medicine, Drugs in renal failure, Food & amp; Drug Administration (FDA) Source Type: info
DiclofenacSodiumInjection(Dyloject): In Postoperative Pain
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Source: Drugs - December 19, 2007 Authors: McCormack, Paul L.Scott, Lesley J. Tags: Adis Drug Profile Source Type: info
Seliciclib, a cell-cycle modulator that acts through the inhibition of cyclin-dependent kinases
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Source: Expert Opinion: Expert Opinion on Drug Discovery: Table of Contents - December 19, 2007 Tags: article Case History Source Type: info
Commentary on the Clinical Relevance of Concentration/QTc Relationships for New Drug Candidates
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Source: The Journal of Clinical Pharmacology - December 19, 2007 Authors: Bloomfield, D., Krishna, R. Tags: Commentaries Source Type: info
Pharmacokinetic Profiles of Controlled-Release Hydrogel Polymer Vaginal Inserts Containing Misoprostol
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Source: The Journal of Clinical Pharmacology - December 19, 2007 Authors: Powers, B. L., Wing, D. A., Carr, D., Ewert, K., Spirito, M. D. Tags: Pharmacokinetics Source Type: info
Letter to the Editor
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Source: The Journal of Clinical Pharmacology - December 19, 2007 Authors: Tressler, C. S., Bean, G. W. Tags: Letter to the Editor Source Type: info
Pharmacological Treatment of Early Multiple Sclerosis.
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Source: Drugs - December 18, 2007 Tags: Abstract HTML PDF (194 K) Source Type: info
Post-Hoc Analysis of a Head-to-Head Hyaluronic Acid Comparison in Knee Osteoarthritis Using the 2004 OMERACT-OARSI Responder Criteria *.
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Source: Clinical Drug Investigation - December 18, 2007 Tags: Abstract HTML PDF (215 K) Source Type: info
NACDS commends House for passing pro-soldier, pro-savings bill
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Source: Drug Topics - Hot off the Press - December 18, 2007 Source Type: info
Prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in female outpatients in South Korea: a multicentre study in 2006.
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Source: International Journal of Antimicrobial Agents - December 18, 2007 Authors: Kim ME, Ha US, Cho YH Tags: Int J Antimicrob Agents Source Type: info
Effects of antiepileptic drugs on neurophysiologic abnormalities subtending migraine
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Source: Drug Development Research - December 18, 2007 Authors: Marina de Tommaso Tags: Research Article Source Type: info
Looking in the wrong place? The search for an ideal migraine preventative
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Source: Drug Development Research - December 18, 2007 Authors: Geoffrey A. Lambert Tags: Research Commentary Source Type: info
Nonoxynol 9 (N9) OTC Contraceptive Products
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Source: Drugs.com - FDA MedWatch Alerts - December 18, 2007 Source Type: info
Buprenorphine/morphine: Coma and respiratory insufficiency: case report
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Heparin/warfarin: Phlegmasia caerulea dolens following heparin withdrawal: case report
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Ropivacaine: Neurotoxicity in an elderly patient: case report
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Etanercept: Recall injection site reactions: 2 case reports
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Carbocisteine: Pneumonia (first report) in an elderly patient: case report
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Paediatric patients at risk for glucocorticoid-induced osteoporosis benefit from treatment with alendronic acid
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Source: Reactions - December 17, 2007 Tags: Research article Source Type: info
Bleomycin: Oxygen toxicity of the lungs: case report
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Sevoflurane: Fatal liver failure in an elderly patient: case report
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Phenytoin: Purple glove syndrome leading to distal limb ischaemia in a catheterised patient: case report
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Ciclosporin: Exacerbation of atopic dermatitis with increased IgE levels: 4 case reports
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Source: Reactions - December 17, 2007 Tags: Short communication Source Type: info
Prasterone [dehydroepiandrosterone] may slow the development of chronic complications in type 2 diabetes mellitus
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Source: Inpharma - December 17, 2007 Tags: Research article Source Type: info
Baclofen battles alcoholism, cirrhosis no barrier
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Source: Inpharma - December 17, 2007 Tags: Short communication Source Type: info
Voriconazole and itraconazole appear to be equally efficacious for paracoccidioidomycosis
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Source: Inpharma - December 17, 2007 Tags: Research article Source Type: info
Single company pharma funding leads to hyped conclusions?
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Source: Inpharma - December 17, 2007 Tags: Short communication Source Type: info
Assessing the risk of triple-class antiretroviral failure
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Source: Inpharma - December 17, 2007 Tags: Short communication Source Type: info
Abatacept: the first T lymphocyte co-stimulation modulator, for the treatment of rheumatoid arthritis
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Source: Expert Opinion: Expert Opinion on Biological Therapy: Table of Contents - December 17, 2007 Tags: article Source Type: info
Infliximab in dermatological treatment: beyond psoriasis
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Source: Expert Opinion: Expert Opinion on Biological Therapy: Table of Contents - December 17, 2007 Tags: article Source Type: info
Varenicline (brand name Champix▼) European wide review
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Source: West Midlands Centre for Adverse Drug Reactions - December 17, 2007 Authors: admin Tags: EMEA Source Type: info
European CHMP issues negative opinion on eprodisate (Kiacta™) for treatment of Amyloid A amyloidosis
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Source: NeLM Headline News - December 16, 2007 Tags: New drugs, European Agency for the Evaluation of Medicinal Products (EMEA), Renal medicine, Infections Source Type: info
Pharmacokinetics and Pharmacodynamics of Ceftobiprole, an Anti-MRSA Cephalosporin with Broad-Spectrum Activity
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Source: Clinical Pharmacokinetics - December 15, 2007 Authors: Murthy, BinduSchmitt-Hoffmann, Anne Tags: Review Article Source Type: info
Anaesthetics/midazolam: Uvular oedema following regional anaesthesia: case report.
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Source: Reactions Weekly - December 14, 2007 Tags: HTML Source Type: info
Sodium tetradecyl sulfate: Anaphylaxis: case report.
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Source: Reactions Weekly - December 14, 2007 Tags: HTML Source Type: info
Iron: Acute iron poisoning: case report.
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Source: Reactions Weekly - December 14, 2007 Tags: HTML Source Type: info
Didanosine: Fanconi's syndrome and nephrogenic diabetes insipidus: case report.
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Source: Reactions Weekly - December 14, 2007 Tags: HTML Source Type: info
Phenytoin: Toxic epidermal necrolysis in an elderly patient undergoing brain radiotherapy: case report.
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Source: Reactions Weekly - December 14, 2007 Tags: HTML Source Type: info
Healthcare costs are predicted to increase vastly in the US within the next 75 years,.
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Source: PharmacoEconomics & Outcomes News - December 14, 2007 Tags: HTML Source Type: info
Patient-directed intervention cost effective for CRC screening.
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Source: PharmacoEconomics & Outcomes News - December 14, 2007 Tags: HTML Source Type: info
Eculizumab significantly improves and stabilises kidney function in patients with paroxysmal nocturnal haemoglobinuria,.
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Source: Inpharma Weekly - December 14, 2007 Tags: HTML Source Type: info
Grass pollen allergy vaccine for SAR improves QOL.
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Source: Inpharma Weekly - December 14, 2007 Tags: HTML Source Type: info
Clevidipine may burst hypertension bubble.
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Source: Inpharma Weekly - December 14, 2007 Tags: HTML Source Type: info
